LOCUS       gnlProkkaBLIJHABK_21    9926 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BLIJHABK_21.
ACCESSION   gnlProkkaBLIJHABK_21
VERSION     gnlProkkaBLIJHABK_21
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 08:09:43
            Original ID  :: gnl|Prokka|BLIJHABK_21
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9926
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9926
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2:9924]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..9924
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..9926
                     /SMILES="NC(C(C)C)C(=O)N1C(CCC1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9926
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             3..4217
                     /NRPS_PKS="Domain: Condensation_LCL (1-192). E-value:
                     2.6e-79. Score: 258.2. Matches aSDomain:
                     nrpspksdomains_ctg21_1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (359-752). E-value:
                     1.2e-115. Score: 378.3. Matches aSDomain:
                     nrpspksdomains_ctg21_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (857-925). E-value: 6.6e-24. Score:
                     75.8. Matches aSDomain: nrpspksdomains_ctg21_1_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (935-1237). E-value:
                     3.7e-167. Score: 549.2. Matches aSDomain:
                     nrpspksdomains_ctg21_1_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1243-1397). E-value: 1.5e-52.
                     Score: 169.4. Matches aSDomain:
                     nrpspksdomains_ctg21_1_TIGR01720.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     343.1; E-value: 3.8e-104)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_1"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-123, bitscore:
                     399.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.1e-17, bitscore:
                     49.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 8.3e-80, bitscore:
                     255.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKPFDLSQAPLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILI
                     REFGELYNNRNLPALRIQYKDYAVWQEGFKTEDAYKTQEAYWLKQLEGELPVLDLPADH
                     TRPPVRSFAGAKVSFTLDQEVTSGLHKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIV
                     GSPIAGRPHKDLEPILGMFVNTLALRTRPEGGKPFVQYLQEVRETALEAFEHQDYPFEE
                     LVDKLELTRDMSRNPLFDVMFVLQNMDQESLELDEMCLKPAANNGHQTSKFDLTLYAQE
                     QPRGLLTFQMEFSTDLYKKKTIEKWLQYFINMLLSIIKDNKAALGTINILNEDETHYLI
                     HELNLTKIDYPRNETISRLFEMQAEQTPNAVAIVSDTQVFTYEDLNSWANQIASVLQIK
                     GVGPDSVVALLTGRTPELIAGMLGILKAGGAYLPIASDLPVERIAYMLSDSGAALLLQS
                     EKTEKQLLDIECEQIIIEDIQKQGETKNIDSSAGPHSLAYIIYTSGSTGKPKGVMIEQR
                     SVIRLVKNSNYITFTPEDRLLMTSSIGFDVGSFEIFGPLLNGAALHLSDQQTFLDSHQL
                     KRYIEHQGITTIWLTSSLFNHLTEQNEQTFSQLKHLIIGGEALSPSHVNRIRNVCPEVS
                     IWNGYGPTENTTFSTCLHIQKTYELSIPIGRPVGNSTAYILNQWGVLQPVGAVGELCVG
                     GDGVARGYLGRPDLTKEKFVPHPFAPGDRLYRTGDLARWLPDGTIEYVGRIDDQVKVRG
                     YRVELGEIESALRQIDGVKEAAVLARTGQSGSKELFGYISVKAGANAEQVRSLLARSLP
                     NYMIPAYIIEMDTLPLTSNGKLNRKALPEPNFTSKQTYAPPRNDLEDQLVLIWQEVLGI
                     QRIGIEDSFFELGGDSIKALQVSARLGRYGLSLPVSDLFRHPKIKDLSPFIRKSERIIE
                     QGPVQGDVPWTPVQQWFFSQDIEERHHFNQSVMLFHSGRLSENALRPALKKLAEHHDAL
                     RMVYRNDDRRWIQINQGIHESQLYSLRTSDLSQSESGWETQIKQEVADLQQSINLQDGP
                     LLHAALFKTLTGDYLFLAIHHLVVDGVSWRILLEDLSAGYQQAAAGQTIQLPPKTDSYQ
                     EYARRIQEYAQSSKLIREEAYWRNVEEQQAAALPYEIPHHVNIDSSKRDSLNFSLTEAD
                     TAVLLQNVNHAYGTDTQDILLTAASLAICEWTGGSKLRIAMEGHGREHILPELDISRTV
                     GWFTSMYPALISFENHRNELGTALKTVKDTLGRIPNKGVGYGMLKYLTNPENKSITSSK
                     TPEISFNYLGQFNDIERQDTFRPSSLGSGRDITHTWKREQIIEMSAMAADKKLHFNLSY
                     PPARFHRNTMEQLINRIEHFLLDIMKHCAGQQKTEKTLSDFSSQSLTAEDLDSISSLVE
                     EL"
     aSDomain        6..578
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.60E-79"
                     /label="ctg21_1_Condensation_LCL.1"
                     /locus_tag="ctg21_1"
                     /protein_end="192"
                     /protein_start="1"
                     /score="258.2"
                     /tool="antismash"
                     /translation="IKPFDLSQAPLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILIR
                     EFGELYNNRNLPALRIQYKDYAVWQEGFKTEDAYKTQEAYWLKQLEGELPVLDLPADHT
                     RPPVRSFAGAKVSFTLDQEVTSGLHKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVG
                     SPIAGRPHKDLEPILGMFVNTLALRTRP"
     aSModule        6..4193
                     /complete
                     /domains="nrpspksdomains_ctg21_1_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg21_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg21_1_PCP.1"
                     /domains="nrpspksdomains_ctg21_1_Epimerization.1"
                     /domains="nrpspksdomains_ctg21_1_TIGR01720.1"
                     /locus_tags="ctg21_1"
                     /monomer_pairings="Val -> D-Val"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       93..158
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0001"
                     /evalue="5.20E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg21_1"
                     /protein_end="52"
                     /protein_start="30"
                     /score="31.8"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNILIREFGELY"
     CDS_motif       189..218
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0002"
                     /evalue="1.30E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg21_1"
                     /protein_end="72"
                     /protein_start="62"
                     /score="14.6"
                     /tool="antismash"
                     /translation="QYKDYAVWQE"
     CDS_motif       480..569
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0003"
                     /evalue="1.60E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg21_1"
                     /protein_end="189"
                     /protein_start="159"
                     /score="49.4"
                     /tool="antismash"
                     /translation="DIIVGSPIAGRPHKDLEPILGMFVNTLALR"
     CDS_motif       618..737
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0004"
                     /evalue="1.00E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg21_1"
                     /protein_end="245"
                     /protein_start="205"
                     /score="72.6"
                     /tool="antismash"
                     /translation="RETALEAFEHQDYPFEELVDKLELTRDMSRNPLFDVMFVL"
     aSDomain        1080..2258
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_AMP-binding.1"
                     /evalue="1.20E-115"
                     /label="ctg21_1_AMP-binding.1"
                     /locus_tag="ctg21_1"
                     /protein_end="752"
                     /protein_start="359"
                     /score="378.3"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEMQAEQTPNAVAIVSDTQVFTYEDLNSWANQIASVLQIKGVGPD
                     SVVALLTGRTPELIAGMLGILKAGGAYLPIASDLPVERIAYMLSDSGAALLLQSEKTEK
                     QLLDIECEQIIIEDIQKQGETKNIDSSAGPHSLAYIIYTSGSTGKPKGVMIEQRSVIRL
                     VKNSNYITFTPEDRLLMTSSIGFDVGSFEIFGPLLNGAALHLSDQQTFLDSHQLKRYIE
                     HQGITTIWLTSSLFNHLTEQNEQTFSQLKHLIIGGEALSPSHVNRIRNVCPEVSIWNGY
                     GPTENTTFSTCLHIQKTYELSIPIGRPVGNSTAYILNQWGVLQPVGAVGELCVGGDGVA
                     RGYLGRPDLTKEKFVPHPFAPGDRLYRTGDLARWLPDGTIEYVGRIDDQVKVR"
     CDS_motif       1266..1304
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0005"
                     /evalue="1.90E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg21_1"
                     /protein_end="434"
                     /protein_start="421"
                     /score="14.8"
                     /tool="antismash"
                     /translation="LGILKAGGAYLPI"
     CDS_motif       1491..1547
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0006"
                     /evalue="1.20E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg21_1"
                     /protein_end="515"
                     /protein_start="496"
                     /score="33.1"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVMIE"
     CDS_motif       2052..2141
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0007"
                     /evalue="5.00E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg21_1"
                     /protein_end="713"
                     /protein_start="683"
                     /score="57.1"
                     /tool="antismash"
                     /translation="PVGAVGELCVGGDGVARGYLGRPDLTKEKF"
     CDS_motif       2223..2288
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0008"
                     /evalue="2.10E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg21_1"
                     /protein_end="762"
                     /protein_start="740"
                     /score="38.9"
                     /tool="antismash"
                     /translation="YVGRIDDQVKVRGYRVELGEIE"
     aSDomain        2574..2777
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_PCP.1"
                     /evalue="6.60E-24"
                     /label="ctg21_1_PCP.1"
                     /locus_tag="ctg21_1"
                     /protein_end="925"
                     /protein_start="857"
                     /score="75.8"
                     /tool="antismash"
                     /translation="EDQLVLIWQEVLGIQRIGIEDSFFELGGDSIKALQVSARLGRYGL
                     SLPVSDLFRHPKIKDLSPFIRKS"
     aSDomain        2808..3713
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_Epimerization.1"
                     /evalue="3.70E-167"
                     /label="ctg21_1_Epimerization.1"
                     /locus_tag="ctg21_1"
                     /protein_end="1237"
                     /protein_start="935"
                     /score="549.2"
                     /tool="antismash"
                     /translation="GDVPWTPVQQWFFSQDIEERHHFNQSVMLFHSGRLSENALRPALK
                     KLAEHHDALRMVYRNDDRRWIQINQGIHESQLYSLRTSDLSQSESGWETQIKQEVADLQ
                     QSINLQDGPLLHAALFKTLTGDYLFLAIHHLVVDGVSWRILLEDLSAGYQQAAAGQTIQ
                     LPPKTDSYQEYARRIQEYAQSSKLIREEAYWRNVEEQQAAALPYEIPHHVNIDSSKRDS
                     LNFSLTEADTAVLLQNVNHAYGTDTQDILLTAASLAICEWTGGSKLRIAMEGHGREHIL
                     PELDISRTVGWFTSMYPALIS"
     CDS_motif       2820..2846
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0009"
                     /evalue="3.90E-03"
                     /label="NRPS-E1"
                     /locus_tag="ctg21_1"
                     /protein_end="948"
                     /protein_start="939"
                     /score="10.4"
                     /tool="antismash"
                     /translation="WTPVQQWFF"
     CDS_motif       2901..2984
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0010"
                     /evalue="6.50E-04"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg21_1"
                     /protein_end="994"
                     /protein_start="966"
                     /score="12.2"
                     /tool="antismash"
                     /translation="SGRLSENALRPALKKLAEHHDALRMVYR"
     CDS_motif       3189..3254
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0011"
                     /evalue="1.50E-12"
                     /label="NRPS-E2"
                     /locus_tag="ctg21_1"
                     /protein_end="1084"
                     /protein_start="1062"
                     /score="39.5"
                     /tool="antismash"
                     /translation="LFLAIHHLVVDGVSWRILLEDL"
     CDS_motif       3660..3707
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0012"
                     /evalue="6.80E-09"
                     /label="NRPS-E5"
                     /locus_tag="ctg21_1"
                     /protein_end="1235"
                     /protein_start="1219"
                     /score="27.7"
                     /tool="antismash"
                     /translation="DISRTVGWFTSMYPAL"
     aSDomain        3732..4193
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_TIGR01720.1"
                     /evalue="1.50E-52"
                     /label="ctg21_1_TIGR01720.1"
                     /locus_tag="ctg21_1"
                     /protein_end="1397"
                     /protein_start="1243"
                     /score="169.4"
                     /tool="antismash"
                     /translation="ELGTALKTVKDTLGRIPNKGVGYGMLKYLTNPENKSITSSKTPEI
                     SFNYLGQFNDIERQDTFRPSSLGSGRDITHTWKREQIIEMSAMAADKKLHFNLSYPPAR
                     FHRNTMEQLINRIEHFLLDIMKHCAGQQKTEKTLSDFSSQSLTAEDLDSI"
     CDS_motif       3756..3818
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0013"
                     /evalue="1.40E-09"
                     /label="NRPS-E6"
                     /locus_tag="ctg21_1"
                     /protein_end="1272"
                     /protein_start="1251"
                     /score="30.2"
                     /tool="antismash"
                     /translation="VKDTLGRIPNKGVGYGMLKYL"
     CDS_motif       3858..3887
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0014"
                     /evalue="4.60E-03"
                     /label="NRPS-E7"
                     /locus_tag="ctg21_1"
                     /protein_end="1295"
                     /protein_start="1285"
                     /score="9.6"
                     /tool="antismash"
                     /translation="PEISFNYLGQ"
     aSDomain        4243..4332
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_NRPS-COM_Nterm.1"
                     /evalue="1.70E-18"
                     /label="ctg21_2_NRPS-COM_Nterm.1"
                     /locus_tag="ctg21_2"
                     /protein_end="30"
                     /protein_start="0"
                     /score="57.5"
                     /tool="antismash"
                     /translation="MTKANSIQDIYPLSYMQEGMLFHSLLQKDS"
     CDS             4243..9924
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-30). E-value: 1.7e-18.
                     Score: 57.5. Matches aSDomain:
                     nrpspksdomains_ctg21_2_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-304). E-value:
                     5.9e-118. Score: 385.2. Matches aSDomain:
                     nrpspksdomains_ctg21_2_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (468-865). E-value:
                     2.3e-103. Score: 337.8. Matches aSDomain:
                     nrpspksdomains_ctg21_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (971-1040). E-value: 5.7e-24. Score:
                     76.0. Matches aSDomain: nrpspksdomains_ctg21_2_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1054-1333). E-value:
                     1.2e-103. Score: 338.1. Matches aSDomain:
                     nrpspksdomains_ctg21_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1499-1894). E-value:
                     1.6e-109. Score: 358.1. Matches aSDomain:
                     nrpspksdomains_ctg21_2_AMP-binding.2"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     384.6; E-value: 1.3e-116)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_2"
                     /sec_met_domain="Condensation (E-value: 3.7e-89, bitscore:
                     285.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2e-111, bitscore:
                     359.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-15, bitscore:
                     45.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKANSIQDIYPLSYMQEGMLFHSLLQKDSQAYVEQASFTIEGKV
                     NPQFFQNSINALVERHDIFRTIFISQNVSSPQQVVLRERNVIVLEEDITHLNEAEQSQF
                     IEQWKEKDRDRGFHLQKDVLMRIALIQTGESQYTCIWTFHHIMMDGWCLSIVLKEFLHI
                     YASYVNASPITLEPVQPYGKYIKWLMEQNKEQAVSYWDHYLSGHEQQTVLPKQKKTKGK
                     SRQEHVTFSFSKEESSRLSELAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGSVISGR
                     PAEIEGIEHMVGLFINTMPVRVQGAKTPFLQLIKDMQKDRLAAEAYSYHPLYEIQSRSA
                     VKQGLIDHILVFENYPVQQEIQMLNKQEHASDLFQIHNFTVADETNYSFYLMVAPGEEI
                     HIKMNYDAEQHDRSFVLSVKEHLLNAVSQILNNPNLPPEEIDITTDTEKRQLIGEITDR
                     TPVYETIHEMFEKQAEKTPDAYAVKDQFCSLTYKELNKSANRLARHLRMKGVARQEPVA
                     IMMERSTAFITGVLGILKAGGAIVPVDPHYPADRIRYILHDCGCSHIVSQAHLSSSLED
                     NYIITHPEDIESKIDGSNIKSVNNADDLLYMIYTSGTTGKPKGVQFEHRNMANLLKFEY
                     THSGIDFEADVLQFATPSFDVCYQEIFSALLKGGTLHIVPEAIKRDVPQLFAFINKHHT
                     NIVFLPTAFIKMIFSERELANSFPDGVKHLIAAGEQLMISDLFQDVLRERGIHLHNHYG
                     PSETHVVSTYTIHPGDPIPELPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISGASVA
                     RGYVNHDKLTSDKFSSDPFRPGVIMYRTGDLARRLEDGNIEYIGRADNQVKIRGYRIEP
                     QEIEVTLMNHPDISEAAILIWQDQNGEHELYAYYCSVQKLNAIDLRSYMASDLPEYMIP
                     AKWIWVDSIPLTPNGKVDRAALPGPDASISGNPYTAPRNLLEAKLSQLFEDVLKNGHIG
                     IQDNFFDNGGHSLKATVLMSRIAKEFHVQVSLKDIFAHPTVEGLASIIREAEQNPYAAI
                     EPAEERDTYPVSSAQKRIYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVCKELINRHE
                     PLRTSFASGADDEPVQRIHTEVPFTLSKETTIEGFVRPFDLSQAPLFRAGLIEVSNEKH
                     VLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQQFKKGDSYQKQE
                     TYWQQQFSGDLPILELPTDKRRPAERQFIGGKVTFQLDKEITARIKRLAHKNRSTLYMT
                     LLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRPAGNKTFEEFL
                     KEVRQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVLQNMEQQKLKMNDVQLQ
                     WNDLEHPISKFDISLYVTEHDSELFCQFEYSTALFEKETIQRWASLFTTLVEHTAASPE
                     TELDNISILTKKEERDFIEACHPFEETGYSMNQTLHYALEQQAAKTPDQTAVIFEDGVM
                     TYKELNEQANRIAWELIGRGVKRETTVAIIGKRSPEMLLGIYGILKAGGAYLPIDPDYP
                     EERISFLLEDSGTNILLLQSAGLHVPAFAGEIVYLNQTNSGLTHRFSNPKVDILPQSLA
                     YVIYTSGSTGRPKGVEVEHRSAVNFLNSLQSRYRLKQSDVIMHKTSYSFDASIWELFWW
                     PYAGASVYLLPQGGEKEPEVIAKAIEEQKITAMHFVPSMLHAFLEHIKYRSVPIKTNRL
                     KRVFSGGEQLGTHLVSRFHELLPNVSITNSYGPTEATVEAAFFDCPPHEKLERIPIGKP
                     VHHVRLYILNQNQRMLPAGCIGELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYK
                     TGDVARWLPDGNVEFLGRTD"
     aSDomain        4264..5154
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="5.90E-118"
                     /label="ctg21_2_Condensation_DCL.1"
                     /locus_tag="ctg21_2"
                     /protein_end="304"
                     /protein_start="7"
                     /score="385.2"
                     /tool="antismash"
                     /translation="QDIYPLSYMQEGMLFHSLLQKDSQAYVEQASFTIEGKVNPQFFQN
                     SINALVERHDIFRTIFISQNVSSPQQVVLRERNVIVLEEDITHLNEAEQSQFIEQWKEK
                     DRDRGFHLQKDVLMRIALIQTGESQYTCIWTFHHIMMDGWCLSIVLKEFLHIYASYVNA
                     SPITLEPVQPYGKYIKWLMEQNKEQAVSYWDHYLSGHEQQTVLPKQKKTKGKSRQEHVT
                     FSFSKEESSRLSELAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGSVISGRPAEIEGI
                     EHMVGLFINTMPVRVQ"
     aSModule        4264..7362
                     /complete
                     /domains="nrpspksdomains_ctg21_2_Condensation_DCL.1"
                     /domains="nrpspksdomains_ctg21_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg21_2_PCP.1"
                     /locus_tags="ctg21_2"
                     /monomer_pairings="Pro -> Pro"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       4273..4314
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0001"
                     /evalue="8.80E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="ctg21_2"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.5"
                     /tool="antismash"
                     /translation="YPLSYMQEGMLFHS"
     CDS_motif       4336..4449
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0002"
                     /evalue="1.30E-15"
                     /label="C2_DCL_024-062"
                     /locus_tag="ctg21_2"
                     /protein_end="69"
                     /protein_start="31"
                     /score="49.7"
                     /tool="antismash"
                     /translation="AYVEQASFTIEGKVNPQFFQNSINALVERHDIFRTIFI"
     CDS_motif       4669..4734
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0003"
                     /evalue="5.00E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg21_2"
                     /protein_end="164"
                     /protein_start="142"
                     /score="35.0"
                     /tool="antismash"
                     /translation="FHHIMMDGWCLSIVLKEFLHIY"
     CDS_motif       4780..4818
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0004"
                     /evalue="3.00E-02"
                     /label="C4_DCL_171-183"
                     /locus_tag="ctg21_2"
                     /protein_end="192"
                     /protein_start="179"
                     /score="7.6"
                     /tool="antismash"
                     /translation="PYGKYIKWLMEQN"
     CDS_motif       5053..5148
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0005"
                     /evalue="9.80E-20"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg21_2"
                     /protein_end="302"
                     /protein_start="270"
                     /score="63.0"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPAEIEGIEHMVGLFINTMPVR"
     CDS_motif       5194..5310
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0006"
                     /evalue="1.80E-20"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="ctg21_2"
                     /protein_end="356"
                     /protein_start="317"
                     /score="65.4"
                     /tool="antismash"
                     /translation="QKDRLAAEAYSYHPLYEIQSRSAVKQGLIDHILVFENYP"
     aSDomain        5647..6837
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_AMP-binding.1"
                     /evalue="2.30E-103"
                     /label="ctg21_2_AMP-binding.1"
                     /locus_tag="ctg21_2"
                     /protein_end="865"
                     /protein_start="468"
                     /score="337.8"
                     /specificity="substrate consensus: Pro"
                     /tool="antismash"
                     /translation="FEKQAEKTPDAYAVKDQFCSLTYKELNKSANRLARHLRMKGVARQ
                     EPVAIMMERSTAFITGVLGILKAGGAIVPVDPHYPADRIRYILHDCGCSHIVSQAHLSS
                     SLEDNYIITHPEDIESKIDGSNIKSVNNADDLLYMIYTSGTTGKPKGVQFEHRNMANLL
                     KFEYTHSGIDFEADVLQFATPSFDVCYQEIFSALLKGGTLHIVPEAIKRDVPQLFAFIN
                     KHHTNIVFLPTAFIKMIFSERELANSFPDGVKHLIAAGEQLMISDLFQDVLRERGIHLH
                     NHYGPSETHVVSTYTIHPGDPIPELPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISG
                     ASVARGYVNHDKLTSDKFSSDPFRPGVIMYRTGDLARRLEDGNIEYIGRADNQVKIR"
     CDS_motif       5833..5874
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0007"
                     /evalue="5.20E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg21_2"
                     /protein_end="544"
                     /protein_start="530"
                     /score="13.5"
                     /tool="antismash"
                     /translation="LGILKAGGAIVPVD"
     CDS_motif       6058..6114
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0008"
                     /evalue="1.40E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg21_2"
                     /protein_end="624"
                     /protein_start="605"
                     /score="26.9"
                     /tool="antismash"
                     /translation="YMIYTSGTTGKPKGVQFEH"
     CDS_motif       6496..6522
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0009"
                     /evalue="4.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg21_2"
                     /protein_end="760"
                     /protein_start="751"
                     /score="4.2"
                     /tool="antismash"
                     /translation="YGPSETHVV"
     CDS_motif       6631..6720
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0010"
                     /evalue="6.40E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg21_2"
                     /protein_end="826"
                     /protein_start="796"
                     /score="40.9"
                     /tool="antismash"
                     /translation="PCGVPGELYISGASVARGYVNHDKLTSDKF"
     CDS_motif       6802..6867
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0011"
                     /evalue="6.20E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg21_2"
                     /protein_end="875"
                     /protein_start="853"
                     /score="37.4"
                     /tool="antismash"
                     /translation="YIGRADNQVKIRGYRIEPQEIE"
     aSDomain        7156..7362
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_PCP.1"
                     /evalue="5.70E-24"
                     /label="ctg21_2_PCP.1"
                     /locus_tag="ctg21_2"
                     /protein_end="1040"
                     /protein_start="971"
                     /score="76.0"
                     /tool="antismash"
                     /translation="EAKLSQLFEDVLKNGHIGIQDNFFDNGGHSLKATVLMSRIAKEFH
                     VQVSLKDIFAHPTVEGLASIIREA"
     aSDomain        7405..8241
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.20E-103"
                     /label="ctg21_2_Condensation_LCL.1"
                     /locus_tag="ctg21_2"
                     /protein_end="1333"
                     /protein_start="1054"
                     /score="338.1"
                     /tool="antismash"
                     /translation="DTYPVSSAQKRIYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVC
                     KELINRHEPLRTSFASGADDEPVQRIHTEVPFTLSKETTIEGFVRPFDLSQAPLFRAGL
                     IEVSNEKHVLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQQFKK
                     GDSYQKQETYWQQQFSGDLPILELPTDKRRPAERQFIGGKVTFQLDKEITARIKRLAHK
                     NRSTLYMTLLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRP"
     aSModule        7405..9924
                     /domains="nrpspksdomains_ctg21_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg21_2_AMP-binding.2"
                     /incomplete
                     /locus_tags="ctg21_2"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       7471..7584
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0012"
                     /evalue="5.10E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg21_2"
                     /protein_end="1114"
                     /protein_start="1076"
                     /score="47.8"
                     /tool="antismash"
                     /translation="AYNMPAVLELEGALDVAKLSAVCKELINRHEPLRTSFA"
     CDS_motif       7756..7821
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0013"
                     /evalue="1.70E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg21_2"
                     /protein_end="1193"
                     /protein_start="1171"
                     /score="30.1"
                     /tool="antismash"
                     /translation="MHHIISDGVSVQLLIREFTDLY"
     CDS_motif       7852..7884
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0014"
                     /evalue="9.40E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg21_2"
                     /protein_end="1214"
                     /protein_start="1203"
                     /score="11.9"
                     /tool="antismash"
                     /translation="QYKDYAVWQQQ"
     CDS_motif       8143..8232
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0015"
                     /evalue="2.50E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg21_2"
                     /protein_end="1330"
                     /protein_start="1300"
                     /score="51.9"
                     /tool="antismash"
                     /translation="DIVIGSPIAGRPHADLEAVLGMFVNTLALR"
     CDS_motif       8281..8400
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0016"
                     /evalue="6.20E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg21_2"
                     /protein_end="1386"
                     /protein_start="1346"
                     /score="66.8"
                     /tool="antismash"
                     /translation="RQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVL"
     aSDomain        8740..9924
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_AMP-binding.2"
                     /evalue="1.60E-109"
                     /label="ctg21_2_AMP-binding.2"
                     /locus_tag="ctg21_2"
                     /protein_end="1894"
                     /protein_start="1499"
                     /score="358.1"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="LEQQAAKTPDQTAVIFEDGVMTYKELNEQANRIAWELIGRGVKRE
                     TTVAIIGKRSPEMLLGIYGILKAGGAYLPIDPDYPEERISFLLEDSGTNILLLQSAGLH
                     VPAFAGEIVYLNQTNSGLTHRFSNPKVDILPQSLAYVIYTSGSTGRPKGVEVEHRSAVN
                     FLNSLQSRYRLKQSDVIMHKTSYSFDASIWELFWWPYAGASVYLLPQGGEKEPEVIAKA
                     IEEQKITAMHFVPSMLHAFLEHIKYRSVPIKTNRLKRVFSGGEQLGTHLVSRFHELLPN
                     VSITNSYGPTEATVEAAFFDCPPHEKLERIPIGKPVHHVRLYILNQNQRMLPAGCIGEL
                     YIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNVEFLGRTD"
     CDS_motif       8929..8967
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0017"
                     /evalue="8.00E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg21_2"
                     /protein_end="1575"
                     /protein_start="1562"
                     /score="15.9"
                     /tool="antismash"
                     /translation="GILKAGGAYLPID"
     CDS_motif       9154..9213
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0018"
                     /evalue="2.70E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg21_2"
                     /protein_end="1657"
                     /protein_start="1637"
                     /score="32.1"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVEVEH"
     CDS_motif       9598..9627
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0019"
                     /evalue="4.00E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg21_2"
                     /protein_end="1795"
                     /protein_start="1785"
                     /score="7.1"
                     /tool="antismash"
                     /translation="SYGPTEATVE"
     CDS_motif       9736..9825
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0020"
                     /evalue="5.30E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg21_2"
                     /protein_end="1861"
                     /protein_start="1831"
                     /score="57.1"
                     /tool="antismash"
                     /translation="PAGCIGELYIAGAGVARGYLNRPALTEERF"
ORIGIN
        1 catttatcaa accgtttgat ctcagccaag cgccgctgtt ccgtgcccaa atcgtaaagg
       61 tatcagatga gcggcacctg ttgctggttg atatgcatca catcatttca gacggtgttt
      121 ccgtcaacat tctgattcgg gaattcggcg aactgtacaa caaccggaat cttccggcac
      181 tgcgcattca atataaagat tatgccgtat ggcaagaagg atttaaaaca gaggacgcgt
      241 acaaaacgca ggaggcgtac tggctgaagc agctcgaggg cgagctgcct gtgctggatc
      301 ttccggctga tcatacccgc ccgcctgtac gaagcttcgc gggtgccaag gtctcattta
      361 cgctggatca agaggttaca tccggccttc acaagctggc acgggaaaac ggaagcacac
      421 tgtacatggt gctccttgcg gcttacaccg cgttcttgtc acgcttaagc ggacaggaag
      481 atatcattgt aggatcgcca atcgccggcc ggccgcacaa ggatcttgag ccgatactcg
      541 gcatgtttgt gaacacgttg gcgcttcgga cacgcccgga gggcgggaag ccattcgtac
      601 agtatttgca ggaagtgcgt gaaacagcat tggaagcctt tgagcaccag gattacccgt
      661 tcgaagaact tgtcgataag cttgaattga caagggatat gagcagaaat ccgctgtttg
      721 acgtaatgtt tgttcttcaa aacatggatc aggaatcgtt ggagctggat gagatgtgtc
      781 tcaaacctgc agcaaacaat gggcatcaaa cgtcaaaatt tgatttaacg ctatatgccc
      841 aggaacagcc ccgcggtttg ctgacgttcc aaatggagtt tagtactgac ttatataaga
      901 aaaaaacgat agaaaagtgg cttcaatact tcatcaatat gttactctcc atcatcaaag
      961 acaacaaagc cgctctcgga acaataaata tcctgaatga ggatgagacc cattacctta
     1021 tccacgagct caatcttaca aaaatagatt atccaagaaa tgaaaccatc agcagactct
     1081 ttgaaatgca ggctgaacaa acgcctaatg ctgtagcaat tgtcagcgac acccaagtat
     1141 tcacttacga ggacctgaac agctgggcaa atcaaattgc ctcagttcta cagattaagg
     1201 gtgtagggcc tgatagtgtt gtagccttgt tgacaggcag aacaccagaa ctcattgcag
     1261 gaatgctggg cattctgaaa gccgggggag cctatctgcc tattgcttct gatctgcctg
     1321 ttgaacgaat agcttatatg ctgtcagaca gcggggcggc attactcctt caatctgaaa
     1381 aaacagaaaa acagctatta gacattgaat gtgaacaaat cataatcgaa gatattcaaa
     1441 agcaaggaga aacgaagaac attgattctt cagcagggcc acattcactt gcatatatca
     1501 tttatacctc tggatcaacc ggtaaaccaa agggtgtcat gattgagcag cgaagtgtaa
     1561 ttcgtcttgt taaaaacagc aattatatta catttacacc tgaagaccgc cttcttatga
     1621 catcatcaat cggtttcgac gttgggtcat ttgaaatttt cggaccgttg ctaaatggtg
     1681 ccgctttgca tctgtccgat caacaaacat ttctcgattc ccatcagctt aagaggtaca
     1741 tagaacatca aggaatcaca acgatttggc tgacatcttc tctattcaat catttgacag
     1801 aacaaaatga acaaacattt tcacagctga aacatttgat tataggcgga gaagctttgt
     1861 cgccgagcca cgtcaatcga atcagaaatg tctgccctga agtatcgata tggaatggat
     1921 atggccctac cgaaaataca actttttcga catgccttca cattcaaaaa acatatgaac
     1981 tttccattcc gatcgggcgg ccggttggta attccaccgc ttatatctta aatcaatggg
     2041 gagtgctgca gccggtcgga gctgtcggtg aactttgtgt cggcggagat ggcgtcgcca
     2101 gaggatattt gggccgtcct gatttaacga aagagaaatt tgtcccacat ccatttgcac
     2161 ctggcgatcg actgtatcgc acaggtgatc tggcgcgctg gcttcctgat ggcacaattg
     2221 agtacgttgg ccgtattgat gatcaagtaa aagtcagagg ctatcgggtg gagctgggtg
     2281 aaatcgaatc agcacttcgc caaatagacg gggtcaaaga agcggcggtg ttggcacgta
     2341 caggacagtc agggagcaaa gagctgtttg gctatatcag cgtaaaagca ggcgcgaatg
     2401 ctgaacaagt gcgttctctt ctcgcgcgtt cgctgccaaa ctatatgatc ccggcgtaca
     2461 ttattgaaat ggatactctt ccgctcacat caaacggcaa attgaaccga aaagcacttc
     2521 ctgaaccaaa tttcacatct aaacaaacgt acgctccgcc tcgaaatgac cttgaagacc
     2581 aacttgtgtt gatctggcag gaggttctcg gcatccagag gatcggaata gaggattcgt
     2641 tttttgaatt gggcggagat tcaatcaaag cgcttcaagt ttctgcacgc cttgggcgct
     2701 atgggctaag cttgccggta agtgatttat tccgtcatcc aaagataaag gacttatcac
     2761 catttatccg taagtcagag agaatcatag agcaaggacc cgttcaggga gacgttcctt
     2821 ggacgcctgt tcagcaatgg tttttttcac aagatattga agaaagacac catttcaatc
     2881 agtctgtcat gctattccat tctggacgtt tgtctgaaaa cgcccttaga ccagccttga
     2941 aaaaactggc ggagcatcat gatgcgcttc ggatggtata tcgcaacgat gataggcgat
     3001 ggattcaaat caaccaaggc attcatgagt cacagctata cagcttaaga acctctgatc
     3061 tttcacagtc agaaagcggc tgggagacgc aaatcaaaca agaagttgca gatcttcagc
     3121 aaagcatcaa tttgcaggac ggaccattgt tgcacgccgc tttgtttaaa acactgaccg
     3181 gagattactt gttccttgcg atccatcacc ttgtcgttga tggtgtctca tggcggattt
     3241 tactggagga tttgtcagcc ggatatcaac aagctgctgc aggccagacg atccagcttc
     3301 cgcctaaaac ggattcctac caggaatacg caagacgcat acaggaatat gcccaaagca
     3361 gtaagctgat tcgcgaagag gcgtattggc gaaatgtaga agaacaacaa gctgcagcac
     3421 tgccatatga aataccgcat catgtgaaca tcgactccag caaaagggac tcattaaact
     3481 tttcactgac tgaagcagac accgccgtct tgctgcaaaa cgtcaatcac gcctatggca
     3541 cagatacaca agatattctg ttaaccgcag catccttggc gatttgtgaa tggacaggag
     3601 gaagcaagct ccgtatcgcc atggaaggac acgggagaga acacattctg ccagagttag
     3661 atatcagcag gacggtcggc tggtttacat ccatgtaccc ggccctcata agctttgaaa
     3721 atcataggaa tgagctcgga accgcattaa aaaccgttaa agatacactg ggccggatac
     3781 caaacaaagg ggtaggttac ggtatgctga aataccttac aaaccctgaa aataaaagca
     3841 ttacgtcttc aaaaacacct gaaatcagct ttaactattt gggccagttc aacgacatcg
     3901 aaagacagga caccttccgc ccatcaagcc ttggtagcgg aagggatatc actcatacat
     3961 ggaagcgtga gcaaatcatc gagatgagtg caatggcagc agacaaaaag ctccatttca
     4021 atcttagtta tccgccagcc cgctttcaca gaaacacaat ggagcagctt attaacagga
     4081 ttgaacactt tttgctggac attatgaaac actgtgccgg tcaacagaaa acagaaaaga
     4141 cactgagcga tttcagcagt caatcattaa cagcagagga cttggacagc atatccagct
     4201 tggtggaaga attgtagaaa atcgtgacag ggagacatga acatgacaaa agcgaattca
     4261 attcaggata tttatccgct gtcttacatg caggaaggga tgcttttcca ttccctcctg
     4321 caaaaagatt cacaggcgta tgttgagcaa gcttctttta caatagaagg aaaagtcaac
     4381 ccgcagtttt ttcaaaacag catcaacgct cttgtagaaa gacatgatat tttcagaacg
     4441 atttttatca gccaaaatgt ttcctccccc cagcaggttg ttctgagaga acgaaatgtc
     4501 atcgtactgg aagaagacat tactcattta aacgaggcgg agcaatcaca gtttatcgag
     4561 caatggaaag aaaaggaccg ggaccggggg tttcatttgc aaaaggatgt gctcatgcgc
     4621 atcgctctta ttcaaacggg agagagccag tacacttgta tttggacctt tcatcacatc
     4681 atgatggacg gttggtgcct cagcattgtg ctaaaggagt ttctgcatat ttacgcatct
     4741 tatgtaaatg catcccctat aacattggag ccggtccagc catacggaaa gtatatcaaa
     4801 tggttgatgg agcaaaacaa agagcaggcg gtttcttatt gggaccatta tctttccggc
     4861 cacgaacagc aaaccgtgct cccgaagcag aaaaaaacaa agggaaaaag caggcaggaa
     4921 cacgttacat tttcattctc taaggaagaa agcagcaggc tttcagagct tgctgcaaga
     4981 gaagaagtga cactcagtac gatttttcat accatttggg gcattctgct acaaaaatat
     5041 aataataacg atgacgccgt attcggttct gtcatttcag gaagacccgc ggaaatcgaa
     5101 ggcattgaac atatggtagg tcttttcatt aatacgatgc cggttcgggt gcagggggca
     5161 aaaacgccat ttcttcaact tataaaagat atgcaaaaag accgtcttgc cgctgaagca
     5221 tacagctacc accctttata tgagattcaa tcccgctcag ctgttaagca agggctgatt
     5281 gatcatattc tcgtatttga aaactatccg gtgcagcaag agattcaaat gctgaacaaa
     5341 caggaacatg cttctgatct ttttcagatt cataatttca ctgtcgcaga tgaaaccaac
     5401 tacagctttt atcttatggt ggcgccaggg gaagaaattc atatcaaaat gaactatgat
     5461 gcggagcagc acgatcggtc ttttgtgctc tctgtcaaag agcatcttct gaatgctgta
     5521 tcacaaatct taaataatcc gaatcttcca cctgaagaaa tcgatatcac gacagatact
     5581 gaaaagcggc agctgattgg agaaatcaca gatcgaacac cagtttacga aaccatccat
     5641 gaaatgtttg aaaagcaagc ggaaaagaca ccggatgctt atgctgtaaa ggatcaattc
     5701 tgctcgttaa catacaaaga actgaataaa tcggctaaca gattggcacg gcatttacga
     5761 atgaaaggcg ttgcgagaca ggagcccgtt gcgattatga tggaacgctc aacggcgttt
     5821 atcaccggcg ttcttggaat cttaaaggca ggcggtgcca ttgttccggt tgatccgcat
     5881 tacccggctg acagaatccg ttatattctg catgattgcg gctgttcgca tattgtttca
     5941 caagcgcatc tttcctcatc gttagaagac aattacatta tcactcatcc agaagatatc
     6001 gaaagcaaga tagacggcag taacataaag tcagtcaaca atgctgacga tctgctgtat
     6061 atgatttata catcaggcac aacaggtaaa ccaaagggtg ttcaatttga gcatcgaaac
     6121 atggctaact tgctgaagtt cgaatatact cactccggca ttgactttga agcagatgtt
     6181 ctgcaatttg cgacaccttc cttcgacgtc tgctatcaag aaatattttc tgcgcttctg
     6241 aaaggcggca cactccacat cgtgccagaa gccataaaaa gagatgtgcc tcagctgttt
     6301 gcatttataa acaagcatca tacgaatatt gtgtttctcc caactgcatt tatcaaaatg
     6361 attttcagcg agcgagaact agcgaactcg tttcctgatg gcgtcaaaca cctgatcgca
     6421 gccggggaac aattaatgat ttcagacctt ttccaagatg tgttgcgtga acgcggcata
     6481 cacctgcaca atcattacgg accttcagaa actcatgtgg tatctacgta taccattcat
     6541 cctggagacc ctattcctga gcttccgcca atcggtaaac cgataggctg tactgatcta
     6601 tatattttga atcatcaaaa acagcttcag ccatgcggcg taccaggcga actctatatt
     6661 tccggcgcaa gtgttgccag aggatatgtc aatcacgata aactgacaag cgacaaattt
     6721 tcatccgacc cattcaggcc tggtgtgatc atgtaccgta caggtgattt ggccagacgg
     6781 cttgaagacg gcaacatcga atatatcgga cgggcagaca atcaagtgaa aatcagaggt
     6841 tatcgaattg agccccaaga aatcgaagtc acgttaatga atcatccgga cattagtgag
     6901 gctgccattc tcatctggca agatcaaaac ggtgaacatg aattatacgc ttactattgc
     6961 agtgtacaaa agctgaatgc aatagattta cgcagttata tggctagtga tctcccagaa
     7021 tacatgattc cggcgaaatg gatatgggtt gacagcatac ctcttacccc aaacggaaaa
     7081 gtagatcgcg cagcacttcc ggggccagat gcttcaatca gcggaaaccc atatactgcc
     7141 cctcgaaatc tgttagaggc aaagctttcg caactatttg aagatgtgct aaagaatgga
     7201 catataggca tccaagacaa cttttttgac aatggcggcc actcgttaaa agcaacagtg
     7261 cttatgtcac ggatcgcaaa ggaattccat gtgcaagttt cgcttaagga catctttgct
     7321 catccgactg ttgaaggatt agcttcaatc attcgagagg cagaacaaaa tccgtatgca
     7381 gcaattgaac cagcagaaga aagggataca tatcctgtat cttcggccca aaaacgaatc
     7441 tatgtgcttc aacagcttga tgagggtgtc gcctataaca tgcctgcggt cttagaactg
     7501 gaaggtgcac tggatgtcgc caaactgtct gctgtatgta aagaactgat caatcggcat
     7561 gagccgcttc gaacttcctt tgcatccgga gctgatgacg agccggttca gcgtatccac
     7621 accgaagtgc cgtttacgtt aagtaaagag accactatcg agggatttgt acgtcccttt
     7681 gatctcagcc aggcgccatt atttagagca ggccttatag aagtgtcaaa cgagaagcat
     7741 gtattgctgg tggatatgca ccatatcatt tcagatggcg tatccgttca gctcctaatc
     7801 cgagaattta ccgatcttta tgcaaaccgg cagcttaagc cattgcggat ccaatataaa
     7861 gattacgccg tatggcagca gcaatttaaa aagggagact cgtaccaaaa gcaggagact
     7921 tactggcagc agcagtttag cggggacctt cctatactgg agcttccaac agataaacga
     7981 cgtccggcag aacggcaatt cataggcgga aaagtaacct ttcaattgga caaagagatc
     8041 acggcccgca taaagcggct cgcccataaa aacagaagca cgctttatat gacgcttctc
     8101 gctttgtatt cagccttttt gtctcggtta agcggtcagg atgatatcgt gattggttca
     8161 cctatcgccg gacggcccca tgccgacctt gaagctgttc ttgggatgtt cgtcaataca
     8221 ttggctctcc gtacacgccc ggcgggtaat aagacatttg aggaatttct gaaagaagtc
     8281 agacagacgg cactagaagc gtatgagcat caggattacc cgtttgaaga gcttgtggac
     8341 aaactcggtg tgcagcggga aatgagccgg aatcctttgt ttgacacaac gctagtcctt
     8401 cagaatatgg aacagcaaaa gctaaaaatg aatgatgtac agcttcagtg gaacgacttg
     8461 gagcacccaa tatcaaaatt tgatatttcc ctatacgtta cagagcatga ttccgagctt
     8521 ttctgtcagt ttgaatacag tacagctttg tttgagaaag aaaccatcca aaggtgggcc
     8581 agccttttca ccacgcttgt ggaacataca gctgccagtc ctgaaacaga attggacaat
     8641 atttcaatct taacaaaaaa agaagagaga gatttcattg aagcatgcca tccgtttgag
     8701 gagacgggct attcaatgaa tcaaactctc cactatgcac tcgaacagca ggcagcaaaa
     8761 acgcctgatc agactgccgt tatctttgaa gatggagtga tgacctataa agaattgaac
     8821 gaacaggcta accgtatcgc ctgggagctg atcggacggg gggtaaaacg cgaaacgact
     8881 gttgccatta taggaaagcg gtcacctgaa atgctgcttg gcatttatgg cattcttaaa
     8941 gctggcggcg cttatctgcc cattgacccg gattatccgg aagaacgaat cagctttctg
     9001 ctggaggaca gcggtacaaa cattcttctg cttcagtctg ccggccttca tgttccggca
     9061 tttgcaggag agattgtcta tctcaatcag acaaatagcg ggctgacaca tcgtttttcc
     9121 aatccgaagg tggacattct cccgcaatct ttagcctatg tcatctatac atccggctct
     9181 accggcaggc ctaagggtgt ggaagttgaa catcgatctg cggtgaattt tttgaattcc
     9241 cttcagtccc gctatcggct gaagcaatca gatgtgatta tgcataaaac atcctattca
     9301 ttcgatgctt caatatggga gctgttttgg tggccttatg ccggagcttc tgtttatctg
     9361 cttcctcagg gaggcgaaaa agaacctgaa gtgatcgcga aggccataga agaacaaaag
     9421 atcacagcta tgcattttgt gccttcaatg ctccatgcat ttttagaaca tataaaatat
     9481 cgctctgtac cgattaagac aaacagactc aagcgagtgt tttctggggg agaacagctg
     9541 gggacccatc ttgtctcccg atttcacgag ttgcttccaa atgtttcaat aaccaattcc
     9601 tatgggccaa cggaagcaac cgtagaagct gcattctttg attgtccgcc gcatgaaaaa
     9661 cttgaacgga tcccaattgg aaaacctgtt catcatgtca gattatatat cctgaatcag
     9721 aatcagcgga tgctgcctgc tggatgtatt ggcgaactgt acattgccgg agcgggtgtt
     9781 gccagaggtt atttgaatcg gccggcatta acggaggagc gttttcttga ggacccgttt
     9841 tacccgggtg aacgcatgta caaaacaggg gatgtggcgc gctggctccc tgacgggaat
     9901 gttgaattcc tcgggcgcac ggatga
//
