LOCUS       gnlProkkaBLIJHABK_4    22193 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BLIJHABK_4.
ACCESSION   gnlProkkaBLIJHABK_4
VERSION     gnlProkkaBLIJHABK_4
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 08:09:43
            Original ID  :: gnl|Prokka|BLIJHABK_4
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22193
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..2193
                     /NRPS_PKS="Domain: AMP-binding (1-318). E-value: 1.4e-84.
                     Score: 275.9. Matches aSDomain:
                     nrpspksdomains_ctg4_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (426-490). E-value: 7.6e-23. Score:
                     72.4. Matches aSDomain: nrpspksdomains_ctg4_1_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (514-723). E-value:
                     5.4e-25. Score: 81.0. Matches aSDomain:
                     nrpspksdomains_ctg4_1_Thioesterase.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 265;
                     E-value: 1.8e-80)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_1"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-97, bitscore:
                     321.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.7e-13, bitscore:
                     44.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERIRYMIEDSGVKLLLKQSHQQHIEFTGTVLNLDQESNYHKNSL
                     NLENNVQSNNLAYVIYTSGTTGAPKGTLLEHKNVVRLLFNSKNVFDFNEKDTWTLFHSF
                     CFDFSVWEMYGALLYGGKLVIVPKTISKNPIQFLQLLKDEEVTILNQTPSYFYLVKDQE
                     LTHSSCDLKVRKVIFGGESLNPSLLKEWKDKYPDIKLINMYGITETTVHVTYKEITEIE
                     IKDGRSNIGKPIPTLNAYILNEQKELQPIGIQGELYIAGEGLARGYLNRPDLTAEKFVD
                     HPFIPGEKLYRTGDLARWLPEGNIEYLGRIDHQVKIRGYRIEIGEIETALLNMEAVQEA
                     IVVAHENDNGDKALCAYYVASESFAVSEMKEKLSVQMPSYMLPSYFIQLEKMPLTPNGK
                     IDRKELPLPDEKNIQTGVEYVAPRTPIETKLAEIWKDILDIKQVGIQDNFFDIGGDSLK
                     VLKLIQSIKERMRTEISFQTVFNAQTIELLALDLMNGNIKLEDETKFTPITHRGNVNVF
                     CFPSRIGIGMTYIEMAYLLEGDYRIYITDFIHDHTNFDDMIREYAENIVQIQEQGPYVF
                     LGYSGGGNIAFEVAKVMEKKGLEVSDIIMLDTTLWNAEVNKRAMKMLSEVNREHTKVPE
                     WMNTKYVQNKINKFTMYLEQLTNEGVLDSNIHNIVIDNSMTKFKKEWANATTKDYIEYD
                     GYGTHDEILQPEYIDKNVSIVKEILKNINKSVMTSI"
     protocluster    1..22193
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:2193]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..2193
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..22193
                     /SMILES="NC(C(O)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22193
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     aSDomain        4..954
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_1_AMP-binding.1"
                     /evalue="1.40E-84"
                     /label="ctg4_1_AMP-binding.1"
                     /locus_tag="ctg4_1"
                     /protein_end="318"
                     /protein_start="1"
                     /score="275.9"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="ERIRYMIEDSGVKLLLKQSHQQHIEFTGTVLNLDQESNYHKNSLN
                     LENNVQSNNLAYVIYTSGTTGAPKGTLLEHKNVVRLLFNSKNVFDFNEKDTWTLFHSFC
                     FDFSVWEMYGALLYGGKLVIVPKTISKNPIQFLQLLKDEEVTILNQTPSYFYLVKDQEL
                     THSSCDLKVRKVIFGGESLNPSLLKEWKDKYPDIKLINMYGITETTVHVTYKEITEIEI
                     KDGRSNIGKPIPTLNAYILNEQKELQPIGIQGELYIAGEGLARGYLNRPDLTAEKFVDH
                     PFIPGEKLYRTGDLARWLPEGNIEYLGRIDHQVKIR"
     aSModule        4..2169
                     /complete
                     /domains="nrpspksdomains_ctg4_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg4_1_PCP.1"
                     /domains="nrpspksdomains_ctg4_1_Thioesterase.1"
                     /final_module
                     /locus_tags="ctg4_1"
                     /monomer_pairings="Thr -> Thr"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       169..228
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0001"
                     /evalue="2.30E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg4_1"
                     /protein_end="76"
                     /protein_start="56"
                     /score="29.3"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGAPKGTLLEH"
     CDS_motif       748..837
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0002"
                     /evalue="1.50E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg4_1"
                     /protein_end="279"
                     /protein_start="249"
                     /score="55.6"
                     /tool="antismash"
                     /translation="PIGIQGELYIAGEGLARGYLNRPDLTAEKF"
     CDS_motif       919..984
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0003"
                     /evalue="5.90E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg4_1"
                     /protein_end="328"
                     /protein_start="306"
                     /score="37.5"
                     /tool="antismash"
                     /translation="YLGRIDHQVKIRGYRIEIGEIE"
     aSDomain        1279..1470
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_1_PCP.1"
                     /evalue="7.60E-23"
                     /label="ctg4_1_PCP.1"
                     /locus_tag="ctg4_1"
                     /protein_end="490"
                     /protein_start="426"
                     /score="72.4"
                     /tool="antismash"
                     /translation="ETKLAEIWKDILDIKQVGIQDNFFDIGGDSLKVLKLIQSIKERMR
                     TEISFQTVFNAQTIELLAL"
     aSDomain        1543..2169
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_1_Thioesterase.1"
                     /evalue="5.40E-25"
                     /label="ctg4_1_Thioesterase.1"
                     /locus_tag="ctg4_1"
                     /protein_end="723"
                     /protein_start="514"
                     /score="81.0"
                     /tool="antismash"
                     /translation="NVFCFPSRIGIGMTYIEMAYLLEGDYRIYITDFIHDHTNFDDMIR
                     EYAENIVQIQEQGPYVFLGYSGGGNIAFEVAKVMEKKGLEVSDIIMLDTTLWNAEVNKR
                     AMKMLSEVNREHTKVPEWMNTKYVQNKINKFTMYLEQLTNEGVLDSNIHNIVIDNSMTK
                     FKKEWANATTKDYIEYDGYGTHDEILQPEYIDKNVSIVKEILKNIN"
     CDS_motif       1705..1773
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0004"
                     /evalue="1.10E-09"
                     /label="NRPS-te1"
                     /locus_tag="ctg4_1"
                     /protein_end="591"
                     /protein_start="568"
                     /score="30.6"
                     /tool="antismash"
                     /translation="QEQGPYVFLGYSGGGNIAFEVAK"
     CDS             2343..2618
                     /locus_tag="ctg4_2"
                     /transl_table=11
                     /translation="MIFGSVINENLKDEIVVTVIATGFIEQEKDVTKPQRPSLNQSIKT
                     HNQSVPKREPKREEPQQQNTVSRHTSQPADDTLDIPTFLRNRNKRG"
     CDS             2921..7222
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: -2.1; E-value: 28.0)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_3"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.7e-54, bitscore:
                     179.4, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKTKNRLISSVLSTVVISSLLFPGAAGASSKVTSPSVKKELQS
                     AESIQNKISSSLKKSFKKKEKTTFLIKFKDQANTEKAAKAAVKKARSKKLSAAKTEYQK
                     RSAVVSSLKVTADESQQDVLKYLNTQKDKGNADQIHSYYVVNGIAVHASKEVMEKVAQF
                     PEVEKVLPNEKRQLFKSSSPFNMKKAQKAIKATDGVEWNVDQIDAPKAWALGYDGTGTV
                     VASIDTGVEWNHPALKEKYRGYNPENPNEPENEMNWYDAVAGEASPYDDLAHGTHVTGT
                     MVGSEPDGTNQIGVAPGAKWIAVKAFSEDGGTDADILEAGEWVLAPKDAEGNPHPEMAP
                     DVVNNSWGGGSGLDEWYRDMVNAWRAADIFPEFSAGNTDLFIPGGPGSIANPANYPESF
                     ATGATDINKKLADFSLQGPSPYDEIKPEISAPGVNIRSSVPGQTYEDGWDGTSMAGPHV
                     SAVAALLKQANASLSVDEMEDILTSTAEPLTDSTFPDSPNNGYGHGLVNAFDAVSAVTD
                     GLGKAEGQVSVEGDDQEPPVYQHEKVTEAYEGGSLPLTLTAEDNVSVTSVKLSYKLDQG
                     EWTEITAKRISGDHLKGTYQAEIPDIKGTKLSYKWMIHDFGGHVVSSDVYDVTVKSSIT
                     AGYKQDFETAPGGWVASGTNNNWEWGVPSTGPNTAASGEKVYGTNLTGNYANSANMNLV
                     MPPIKAPDSGSLFLQFKSWHNLEDDFDYGYVFVLPEGEKNWEQAGVYNGKTSSWTEEEI
                     DLSAYKGQNIQVMFNLQSDESIAKEGWYIDDVVLSDKSAGKTVKKNKLGVEKPSGKQKK
                     KPINPKKAKPSANTAVKHQNKAIQPQVLPLRAQVSVVETGKSTYSDQSTGQYTLKHKAG
                     DYTLMAEAYGYQSKTQKVSLKTDQTTQANFTLEEMKKGTLKGTVINKTTGEPVKGASVY
                     VVEDAAVEPAMTNDKGEYTLEAYEGAYTIKVAASGYYSDEFSVELKGDVTKETALKPFV
                     GYPGEIAYDDGTAENANSYFAAGNGWAVKMTLADGKDKGMLTGGLFRFWDTEFPDPGGT
                     EFKVEVYDATGKDGAPGKKIAGPFNAEALRNGEWTKVDLSSKGIMVDKDFYLVYIQSKP
                     DPYSPGLAMDETGKNSGRNWQYIGGQWEPGDEADGNYMIRALVNYEAAVPEITSPTDKS
                     YTNKENVTVKGNASPGTTVHIYNGEKEAGETKAAADGTFQTGITLNKGENELTATASTD
                     NGTTDASSPITVTLDQEKPELTLDTPKDGGKTNKETLTVKGVVSDDNLKDVKVNGKKAT
                     ITDGSYSARILLENGSNEIKVIATDLAGNKTTKKAVIDVNFDKPVISGLIPGEDKNLKA
                     GESVKIAFSSAEDLDATFTIRMPLTNARASVQNATELPLREISPGRYEGYWTATSSIKA
                     KGAKVEVIVRDDYGNETRKTANGKLNINTEN"
     CDS             7389..8345
                     /locus_tag="ctg4_4"
                     /transl_table=11
                     /translation="MRQERKESDVKIYLDVIWLLNFCFDALLLLLTAFILKRHVKKRRL
                     VGGAFIGSSIVLLMFTPFSPIVEHPAGKLAFSVVIVVVTFGFKRFRFFFQNLFSFYFAT
                     FLMGGGIIGAHSLLQSNSIVQNGVMITNQTGFGDPISWLFIVGGFPALWFFSKRRIEDI
                     ETKNIQYEERVSVQADLGSQTLHVRGLIDSGNQLYDPLTKTPVMIIYIDKLEPIFGTAE
                     TMIIRNTDPLEAIEQLDESFRFLDKMRLIPYRGVGQQNQFLLCVKPDHVTIMTKEEMIS
                     VDKCLIGISTTKLSADGEFDAIIHPKMLSGKAVKHVS"
     CDS             8408..9127
                     /locus_tag="ctg4_5"
                     /transl_table=11
                     /translation="MKKLKLRLTHLWYKLLMKLGLKSDEVYYIGGSEALPPPLSKDEEQ
                     VLLMKLPNGDQAARAILIERNLRLVVYIARKFENTGINIEDLISIGTIGLIKAVNTFNP
                     EKKIKLATYASRCIENEILMYLRRNNKIRSEVSFDEPLNIDWDGNELLLSDVLGTDDDI
                     ITKDIEANVDKKLLKKALEQLNEREKQIMELRFGLVGEEEKTQKDVADMMGISQSYISR
                     LEKRIIKRLRKEFNKMV"
     CDS             9267..10049
                     /locus_tag="ctg4_6"
                     /transl_table=11
                     /translation="MSRNKVEICGVDTSKLPVLKNEEMRKLFRQLQDEGDDSAREKLVN
                     GNLRLVLSVIQRFNNRGEYVDDLFQVGCIGLMKSIDNFDLSHNVKFSTYAVPMIIGEIR
                     RYLRDNNPIRVSRSLRDIAYKALQVRERLISETSKEPTAEDIAKVLEVPHEEIVFALDA
                     IQDPVSLFEPIYNDGGDPIYVMDQISDERNTDSQWIEELALKEGMRRLNDREKMILRKR
                     FFQGKTQMEVAEEIGISQAQVSRLEKAAIKQMNKNIHQ"
     CDS             10197..10991
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 147.2; E-value:
                     1.1e-44)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MILQLDNVSLKRNGKWILRDIHWKVEEKENWVLYGLNGAGKTALL
                     NMLCSYYFPTSGEMQVLGHEFGKTELGEKLRRKIGLVSAALQQKLYPADSAFEIALSGA
                     YASIGLYETPSKKTREKAIGLLEDLGAIEYADRRYETLSQGEKQRALIARALMADPELL
                     ILDEPVTGLDFIAREKLLDTITYIANKENAPSILYVTHHAEEILPVFDKALLLKQGEVF
                     GSGEIKEMLTNQILSAFFDTPIHVLWNQDRPFLTRAEPITNA"
     CDS             11193..12473
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247:acetylornithine deacetylase (Score: 211.9;
                     E-value: 2.4e-64)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_8"
                     /transl_table=11
                     /translation="MDQQIDSLQKKVEEHKEELIQLAKTLISYQTPAPPARNTEGIQSW
                     IAGYLNELGFSIDKWDVYPGDPNVVGKLKGTDSADYYSLIINGHVDVAEVKEDEKWEHD
                     PFHPIEKNGLLIGRGASDMKGGMACVLFAVKLIREAGIELPGDLILQSVIGEEVGEAGT
                     LECCKRGYHADFAIVADTSDMHIQGQGGVITGWIEIKSSQTFHDGTRRNMIHAGGGTFG
                     ASAIEKMAKIIAGLGELERHWSIMKSYPGFKPGTNTINPAVIEGGRHAAFIADECRLWI
                     TVHFYPNETHDQVAAEIEDYVNRLSDSDIWLRENRPVFKWGGSSMIEDRGEIFPALEVD
                     PGHPSVLALTASHQKVKRECPIIDVSQSVTDGGWLYDAGIPCVIYGPGDLHNAHSVNEK
                     VSIEQLVEYTKIILDFIISWCSRKKEQ"
     CDS             12556..12801
                     /locus_tag="ctg4_9"
                     /transl_table=11
                     /translation="MISISEFQVKDVVNVSNGKKLGSIGDIDINVTTGKIQAIILGGNG
                     KVLGFFGKEEELVIPWRNIVKIGEDVILVRLSEPHA"
     CDS             12964..13800
                     /locus_tag="ctg4_10"
                     /transl_table=11
                     /translation="MNTYHPFSLTTPSTLMIQDWAQTNQNNKEVIAGFTTKNGGVSQKP
                     FESLNTGLHVHDKDADVVKNREYIADMFNTDLQSWVFADQTHDNRVQKVTQRDRGKGAR
                     EYHTALKATDGLYTNEKNVFLALCFADCVPLFFYDPVKSLVGVAHAGWKGTVKQIGREM
                     VKQWTEKEGSNPSDIYAVIGPSISGACYTVDDRVMDAVRALPVSADLAVNQTAKAQYQL
                     DLKELNRLILMDSGLASEQISVSGLCTESEPSLFYSHRRDQGKTGRMMSFIGMKEA"
     CDS             13807..14499
                     /locus_tag="ctg4_11"
                     /transl_table=11
                     /translation="MRVVDNLRHINERINEACNRSGRSSDEVTVIAVTKYVSPERAQEA
                     VDAGITCLGENRDAELLRKQELIKGNPEWHFIGSLQSRKAKSVVNSVSYIHSLDRLSLA
                     KEIEKRAEGTVRCFVQVNTSLEPSKHGMKKEEVIPFIQELSGFEHILVAGLMTMAPLTD
                     DQDQIRSCFRSLRELRDQVQKLNQPNAPCTELSMGMSNDFEIAIEEGATYIRIGSSLVG
                     NETGGVQQ"
     CDS             14496..14951
                     /locus_tag="ctg4_12"
                     /transl_table=11
                     /translation="MSMKNKLKNFFSMEDEEYEYEYIETERESHEEHEQKEKPAYTGNK
                     PSGKQNVVSLQSVQKSSKVVLSEPRVYAEAQEIADHLKNRRAVVVNLQRIQHDQAKRIV
                     DFLSGTVYAIGGDIQRIGSDIFLCTPDNVDVSGTISELISEDEHQRW"
     CDS             14958..15230
                     /locus_tag="ctg4_13"
                     /transl_table=11
                     /translation="MILYQVFSVLSLLITIYSFALIIYIFMSWVPSTRETAVGRFLASI
                     CEPYLEPFRKIIPPIAMLDISPIVAILVLRFATTGLWGLYRMIAF"
     CDS             15291..16064
                     /locus_tag="ctg4_14"
                     /transl_table=11
                     /translation="MSDIYQHFRKDERAFIDQALEWKRIVQEQYRMKLTDFLDPREQVI
                     LSAVTGQADVGLAFSGGYDRAERKRAILYPEYITPEESDFELQAFNVRYADKFVSVDHR
                     SLLGALMGIGLKRQKFGDIVFSETAVQLIVSADTADFVAAQLTQAGKAAVSLEKIDLSD
                     LNIPAVDVEIRDDTVSSLRLDAVCASMSRQSRQKSQTLVKNGLVKVNWKVVEDPSYIVA
                     EGDMLSIRGFGRCSLTKIEGKTKKDKWRVTFERQK"
     CDS             16158..16652
                     /locus_tag="ctg4_15"
                     /transl_table=11
                     /translation="MPLTPNDIHNKTFTKSFRGYDEDEVNEFLAQVRKDYEIVLRKKTE
                     LEAKVNELDERIGHFANIEETLNKSILVAQEAAEDVKRNSQKEAKLIVREAEKNADRII
                     NESLSKSRKIAMEIEELKKQSKVFRTRFQMLIEAQLDLLKNDDWDHLLEYEVDAVFEEK
                     E"
     CDS             16994..19759
                     /locus_tag="ctg4_16"
                     /transl_table=11
                     /translation="MDFKDTLLMPKTDFPMRGNLPNREPDIQKKWEEEDIYRLVQERTK
                     DRPKFVLHDGPPYANGDIHMGHALNKILKDFIVRYKSMSGYNAPYVPGWDTHGLPIETA
                     LTKNKKVNRKEMSVAEFRKLCEEYAWKQIEGQREQFKRLGVRGDWENPYVTLKPEYEAQ
                     QIRVFGEMAKRGYIYKGLKPVNWSPSSESALAEAEIEYQDKRSASIYVAFGVKDGKGVL
                     ENGERIIIWTTTPWTIPANLGISVHPDLEYSVIAVGEDRFVVASALVENVASACGFDQY
                     EVTRTVKGKDLENIIAEHPLYGRDSLVMLGEHVTTDAGTGCVHTAPGHGEDDFIIGQKY
                     GLDVLCPVDEKGVMTSEAPGFEGMFYDDANKAITQQLDEKGALVKLEFITHSYPHDWRT
                     KKPTIFRATAQWFASIKDFRSDLLDAIKETKWVPEWGEQRLHNMVRDRGDWCISRQRAW
                     GVPIPVFYAENGEPIITDETIEHVSELFRQHGSNIWFEKEAKDLLPEGFTHPGSPNGTF
                     TKEQDIMDVWFDSGSSHQAVLEEREDLVRPADLYLEGSDQYRGWFNSSLSTAVAVTGKA
                     PYKGVLSHGFALDGEGRKMSKSIGNVVVPAKVMKQLGADILRLWVSSVDYQADVRVSDA
                     ILKQVAEVYRKIRNTFRFLHGNLFDFDPKTNAVAVEDLREVDQYMLIKLNKLIDKVKKA
                     YDEYEFAVVYHSIHNFCTIELSSFYLDFAKDIVYIEHADHPDRRSMQTVFYETLLALVK
                     LSAPILPHTADELWSHLTFVEEQSVQLTDMPETIAVPNSEATEEKFDRFMALRDDVLKA
                     LETARNEKIIGKSLEANLKLYPNKENKELLASIKENLSQLFIVSELTISEENEAPNDAQ
                     SFATGKIAVEKAEGEMCERSRVISKDVGANPKYPTLSLRNAEIVEKYYQK"
     CDS             19904..20278
                     /locus_tag="ctg4_17"
                     /transl_table=11
                     /translation="MNDQLTAIYTELLLMKEELQSRLFEYSCFQVSTSPQAAINQKQKA
                     TLIYHIKEELQDVLLALSKIENGTFGYCEETGAPIPLAKLAVLPTARTANDFLYSVQFE
                     KKTLPIWKSTDIEYGQALYE"
     CDS             20381..20845
                     /locus_tag="ctg4_18"
                     /transl_table=11
                     /translation="MLYYMIALLIIAADQLTKWLVVKNMELGQSIPIIDQVFYITSHRN
                     TGAAWGILAGQMWFFYLITTAVIIGIVYYIQRYTKGQGLLGVALGLMLGGAIGNFIDRA
                     VRQEVVDFIHVIIVNYNYPIFNIADSSLCVGVMLLFIQMLLDSGKKKKEQ"
     CDS             20847..21758
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1279:pseudouridine synthase (Score: 271.8; E-value:
                     1.2e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_19"
                     /transl_table=11
                     /translation="MNQIDITASEEQKSERIDKFLASTENDWSRTQVQQWVKDGQVVVN
                     GSAVKANYKIQPGDQVTVTVPEPEALDVLAEPMDLDIYYEDQDVLVVNKPRGMVVHPAP
                     GHLTGTLVNGLMAHCTDLSGINGVMRPGIVHRIDKDTSGLLMVAKNDMAHESLVNQLVN
                     KTVTRKYTAVVHGLISHDDGTIDAPIGRDKKDRQSMTVTRDGKNAVTHFHVLERFQDFT
                     LVECQLETGRTHQIRVHMKYIGFPLAGDPKYGPRKTIDFNGQALHAGVLGFDHPRTGEY
                     VEFEAPLPEDMAELIENLRKNG"
ORIGIN
        1 gaagagcgaa ttcgttacat gattgaggac tcaggagtga aactattatt aaagcaaagc
       61 catcagcagc atatagaatt tactggcaca gtgctaaatc tagatcagga aagtaactat
      121 cataaaaata gcttgaatct tgaaaacaat gtacagtcaa acaatttagc atatgtgatc
      181 tatacgtcag ggacaacagg tgctcccaaa ggcactttgc ttgaacataa aaatgtggtt
      241 cgtctcttgt ttaacagcaa aaatgttttt gattttaatg aaaaagatac gtggacctta
      301 ttccactctt tctgtttcga cttttctgta tgggaaatgt atggagcact tttgtacggt
      361 ggcaaattag taatagtacc aaaaacgata tcaaagaacc cgatacaatt tttacagttg
      421 ttaaaagatg aggaagtaac aattctaaat caaactccta gttattttta tttagtgaaa
      481 gatcaagaat taactcattc ttcttgtgat ttaaaagtga gaaaagtaat ctttggcgga
      541 gaatcattga atccatcttt attaaaagaa tggaaagata aatatccaga cataaagcta
      601 attaatatgt atggtattac agaaacaacc gttcatgtaa catataaaga gattacagaa
      661 atcgaaataa aagatggaag aagtaacatc ggaaaaccga ttcctacatt aaatgcctat
      721 atattaaatg agcaaaaaga attgcagcca atcggaatac agggagagct atatattgcc
      781 ggagagggtc tagctcgagg ctacttaaac cgcccggatt taacggccga aaagtttgtc
      841 gatcatccgt ttatccctgg tgagaaattg tatcgaactg gagaccttgc cagatggtta
      901 ccggaaggta acattgagta tttaggacgg attgaccatc aagtgaaaat acgcggatac
      961 cggattgaaa ttggagaaat tgaaacagct ttattgaata tggaagctgt acaagaagca
     1021 atcgtggttg cgcatgaaaa cgacaatgga gataaagcgt tatgtgcata ctacgttgcg
     1081 agtgaatctt ttgcggtcag tgagatgaaa gagaaattat ctgtccaaat gccaagctac
     1141 atgcttccat cttattttat tcaactggag aaaatgccgc tgacacctaa cgggaaaatt
     1201 gaccgtaagg aactccctct gcctgatgaa aaaaatatcc agacaggggt tgagtatgta
     1261 gcacctcgta caccaattga aacaaagtta gctgagattt ggaaggacat acttgatata
     1321 aaacaagtgg gaatacagga taacttcttt gatataggag gtgattcatt aaaagtatta
     1381 aaactaatac aatctataaa agaacgaatg aggactgaaa tttcatttca aacagtattt
     1441 aatgctcaaa ccattgaatt attagcattg gatctaatga atgggaatat aaaattagaa
     1501 gatgaaacaa agtttacacc aataactcat cgtggaaacg tcaatgtgtt ttgcttcccg
     1561 tctcgcatag gaattgggat gacatatata gagatggctt atttgttaga gggagattat
     1621 agaatatata ttacggactt tattcatgat cacacaaatt ttgatgatat gattcgtgaa
     1681 tatgcagaga atatagttca aatacaagaa caaggtccat atgtatttct ggggtattct
     1741 ggaggaggaa atatagcatt tgaagttgca aaggtaatgg aaaagaaagg attggaagtg
     1801 tcagatataa taatgttaga tacaactctt tggaatgccg aagtaaataa aagagcaatg
     1861 aaaatgctat cagaagttaa tcgtgaacat acaaaggttc cagaatggat gaatacgaaa
     1921 tatgtacaaa ataaaattaa taaatttaca atgtatttgg aacagctaac gaatgaagga
     1981 gtattagatt ctaatattca caatattgta atagataatt caatgactaa atttaaaaag
     2041 gagtgggcaa atgcaacaac aaaagattat atagaatatg atggctatgg gacacatgac
     2101 gaaattttgc aacctgaata tatcgataaa aatgtttcaa tagtcaaaga aatattaaaa
     2161 aatataaaca agtctgttat gacatcgatt taaactgttt ttttaattct aaaatacaga
     2221 gagtattttc cgcgaaatat ttttcctaat aatgtgaaat aagaaattaa attatgtcaa
     2281 gaaatttata ataacaggtt tttaattctt ttgtcgcttc ggcgtctgat caagacgtaa
     2341 acatgatttt cggttctgtt attaatgaaa atctaaaaga tgagattgtg gtgacagtga
     2401 ttgcaaccgg ctttatcgaa caagagaagg acgtgacgaa gcctcagcgt ccaagcttaa
     2461 atcaaagcat caaaacacac aatcaaagtg ttccgaagcg tgagccaaaa cgtgaggagc
     2521 ctcagcagca gaacacagta agccgtcata cttcacaacc ggctgatgat acgcttgaca
     2581 tcccgacatt cttaagaaac cgtaataaac gcggctaatg taaaggacaa aatcgttttc
     2641 gattttgtcc ttttttgttt ttctcttcac actctccttc ttataaagtc tttttcccta
     2701 ttgcttcctt cgcttagtaa caaaacagat aattagacct atttattttt gtgacatttt
     2761 tatcattttc atatatatgg aaattgaatg acatgaaacg acaatatctg taattcagat
     2821 tgtctacagt taatatacag cgatgttctg acaaaccatt cattattaaa aggagggacg
     2881 acactttttt taaaaagcat gttgaaaaag ggggatgaaa atgaagaaaa aaacgaaaaa
     2941 cagactcatc agctctgttt taagtacagt tgtcatcagt tcactgctgt ttccgggagc
     3001 agccggggca agcagtaaag tcacctcacc ttctgttaaa aaggagcttc aatctgcgga
     3061 atccattcaa aacaagattt cgagttcatt aaagaaaagc tttaaaaaga aagaaaaaac
     3121 gacttttctg attaaattta aagatcaggc taacacagaa aaagcggcaa aagcggctgt
     3181 taaaaaagcg agatcgaaga agctgtctgc cgctaagacg gaatatcaaa agcgttctgc
     3241 tgttgtgtca tctttaaaag tcacagccga tgaatcccag caagatgtcc taaaatactt
     3301 gaacacccag aaagataaag gaaatgcaga ccaaattcat tcttattatg tggtgaacgg
     3361 gattgctgtt catgcctcaa aagaggttat ggaaaaagtg gcgcagtttc ccgaagtgga
     3421 aaaggtgctt cctaatgaga aacggcagct ttttaagtca tcctccccat ttaatatgaa
     3481 aaaagcacag aaagctatta aagcaactga cggtgtggaa tggaatgtag accaaatcga
     3541 tgccccaaaa gcttgggcac ttggatatga tggaactggc acggttgttg cgtccattga
     3601 taccggtgtg gaatggaatc atccggcatt aaaagagaaa tatcgcggat ataatccgga
     3661 aaatcctaat gagcctgaaa atgaaatgaa ctggtatgat gccgtagcag gcgaggcaag
     3721 cccttatgat gatttggctc atggaaccca tgtgacaggc acgatggtgg gctctgaacc
     3781 ggatgggaca aatcaaatcg gtgtagcgcc tggcgcaaaa tggattgctg ttaaagcgtt
     3841 ctctgaagat ggcggcactg atgctgacat tttggaagct ggtgaatggg ttttagcacc
     3901 aaaggacgcg gaaggaaatc cccacccgga aatggctcct gatgttgtca ataactcatg
     3961 gggagggggc tctggacttg atgaatggta cagagacatg gtcaatgcct ggcgtgcggc
     4021 cgatattttc cctgagtttt cagcggggaa tacggatctc tttattcccg gcgggcctgg
     4081 ttctatcgca aatccggcaa actatccaga atcgtttgca actggagcga ctgatatcaa
     4141 taaaaagctc gctgactttt ctcttcaagg gccatctcca tatgatgaga taaagccgga
     4201 aatatctgca ccgggcgtta atattcgttc atccgttccc ggtcagacat atgaggatgg
     4261 ttgggacggc acatcaatgg cagggccgca tgtatccgct gttgctgcac tgctgaaaca
     4321 ggcgaatgcc tcactttctg ttgatgagat ggaggatata ttaaccagca cggctgaacc
     4381 gctcacggat tcaacatttc ctgattcacc gaataacgga tatggccatg gtctggtgaa
     4441 tgcttttgat gctgtatccg ctgttacaga tggattaggg aaagcggaag gacaagtttc
     4501 tgtagagggg gatgaccaag agcctcctgt ctatcagcat gagaaagtaa ctgaagctta
     4561 tgaaggtggc agcctgccac ttactttgac agctgaagac aatgtgagtg tgacatctgt
     4621 aaagctgtcc tacaagcttg atcaaggtga atggacagaa ataacggcga aacgaatcag
     4681 cggtgatcat ctaaaaggaa cgtatcaagc agagatccca gacataaaag gaactaaact
     4741 aagctataag tggatgattc acgattttgg cggtcatgtc gtttcgtctg acgtatacga
     4801 tgtaacagtg aaatcaagca tcacggcggg atataagcag gactttgaaa ctgcacccgg
     4861 cggctgggtt gcgagcggaa caaataataa ctgggaatgg ggagttccgt caactggccc
     4921 aaatacagca gcatccggag aaaaagtata tggaacgaat ttgacaggaa attatgccaa
     4981 ctcagcaaac atgaaccttg ttatgcctcc tattaaagca cctgattcag gaagtctgtt
     5041 ccttcaattt aaaagctggc acaatttaga ggatgatttt gattacggct acgtttttgt
     5101 tcttccggaa ggtgaaaaga attgggagca ggctggtgtc tataacggaa agacatcaag
     5161 ctggacggag gaagaaattg atttatcggc ttataaaggc caaaacattc aagtgatgtt
     5221 taaccttcaa tctgatgaaa gcattgcaaa agagggctgg tatattgatg atgtagtgct
     5281 ttctgacaaa tcagccggaa aaacagtcaa aaagaataag ctgggcgtcg aaaagccgtc
     5341 tggaaagcaa aagaaaaagc caataaatcc gaaaaaggct aagccatctg caaacacagc
     5401 ggtaaaacat cagaacaagg ctatacagcc tcaagttttg ccgctcaggg cacaagtcag
     5461 tgtagtggaa acaggaaaat caacatattc agatcaatcc acagggcagt acacgctgaa
     5521 gcacaaagcg ggagactata cgcttatggc agaagcatat ggttatcagt cgaaaacaca
     5581 aaaagtatct ttaaagacgg atcagacgac acaagctaat tttacgttag aagagatgaa
     5641 gaagggcaca ttaaaaggca cggtcatcaa taaaacgaca ggagagccgg taaaaggcgc
     5701 ttccgtttat gttgtagagg atgctgcggt ggaaccggct atgacaaacg acaaaggtga
     5761 atatacgctg gaggcctatg aaggcgctta tacgattaaa gtcgctgcat cgggttatta
     5821 cagtgatgaa ttttccgttg agttaaaagg tgacgttaca aaagaaactg cattgaagcc
     5881 tttcgtcggt tatccgggtg aaattgcata tgatgacgga acagcggaga atgccaattc
     5941 ctattttgct gccgggaacg gatgggcagt aaaaatgacg ctcgctgacg gcaaggacaa
     6001 aggcatgctt acaggagggc tgttcagatt ctgggataca gagttccctg atcccggcgg
     6061 cacagagttt aaggttgagg tatacgatgc cacaggaaaa gacggagcac cgggcaagaa
     6121 aattgccggg ccatttaacg ctgaagctct tcgcaatggc gagtggacta aggtagatct
     6181 cagttcaaaa gggattatgg tcgataaaga cttttatctc gtatatatcc agtcgaaacc
     6241 tgacccgtat tcacctggac tggcaatgga tgaaaccggc aagaattccg gccgcaactg
     6301 gcagtatata ggtggacaat gggagccggg tgacgaagca gacggcaact atatgattcg
     6361 cgcattagtt aattatgaag ctgctgtacc tgagattact tcaccgacag acaaatcata
     6421 cacaaataag gagaacgtca ctgtaaaagg aaacgcttct cctggcacaa cggtacacat
     6481 ttataatgga gagaaagaag caggagaaac gaaagctgcc gcggacggca cgttccagac
     6541 aggcatcaca ctcaacaagg gtgaaaatga gctgacggca actgcatcaa ctgacaacgg
     6601 aacaacagat gcctccagcc caatcacggt cacgcttgat caagaaaagc ctgagttaac
     6661 gctggacact ccaaaggatg gcgggaaaac aaataaagaa acgctgactg tcaaaggggt
     6721 tgtatccgat gacaatctga aagacgtcaa ggtgaatggc aaaaaagcaa caataactga
     6781 tggttcatac tcagcccgta ttcttttgga gaatggaagc aatgaaatca aggtgattgc
     6841 tacagacttg gcaggcaaca aaaccacgaa aaaggctgtc attgatgtca attttgacaa
     6901 gcctgtcatt tccggcttaa ttccgggaga ggataaaaac ttaaaagctg gtgaatctgt
     6961 gaaaatcgct ttctcaagcg ctgaggattt agatgcaacg tttaccattc gtatgccgct
     7021 gaccaatgca agagcgagtg tgcaaaatgc cactgaactc ccgttaagag aaatttctcc
     7081 gggaagatat gaaggctatt ggacagccac ttcttctatt aaagcaaaag gagcaaaagt
     7141 agaagtgatc gtccgagatg attatggaaa tgaaacaaga aaaactgcga atggaaaact
     7201 taatatcaac acagaaaatt aagtggaaaa aagctgccgt cattggcagc tttttttata
     7261 tcctctcatt atacttcctc gacaaattaa gcagatttcc ctgaaaaatt gtattttcct
     7321 ctcaacatta attgacagac tttcccacag agcttgcttt atacttatga agcaagaagg
     7381 ggaacagcgt gaggcaagaa agaaaggagt cagatgtgaa aatctattta gatgtcattt
     7441 ggctgttaaa cttttgtttt gatgcacttt tgcttttgct cacggcattt attttaaaac
     7501 ggcatgtaaa aaaaagaaga ctggtaggcg gagcgttcat cggttccagt attgtccttt
     7561 tgatgtttac tcctttttcg ccgattgttg aacatccggc tgggaagcta gctttttcag
     7621 ttgtgattgt ggtggtgaca tttggcttta aaagatttcg gtttttcttt caaaatttgt
     7681 tttcctttta ttttgccact tttttaatgg ggggaggaat tatcggagcc cattctttgc
     7741 tgcagtcaaa ttctattgtt caaaacggtg tcatgattac caatcaaaca gggtttggag
     7801 acccgatcag ctggttgttt attgttggtg gctttccagc attatggttt ttttctaaaa
     7861 gaagaattga agatattgaa acaaaaaaca ttcaatatga ggaacgagtc agcgtgcagg
     7921 cagatttggg cagccaaaca cttcatgtca gaggcctgat tgattccggt aatcagctgt
     7981 acgatcctct tacaaaaaca ccggtaatga tcatttacat tgataaactg gagccgattt
     8041 tcggaacagc cgaaacgatg atcattcgaa acacagaccc attggaagcc atcgaacagc
     8101 tcgatgaatc ctttcgcttt ttagataaaa tgaggttgat tccatacagg ggagttggtc
     8161 agcaaaatca atttttatta tgcgttaaac cggatcacgt aacgattatg acaaaagaag
     8221 aaatgatttc tgtagataaa tgtttaatcg gcatcagcac aacaaagctg tcggcagatg
     8281 gagagtttga cgcgattatt catccgaaaa tgctttcggg caaggctgtc aaacacgttt
     8341 cataatgttc gcaaatgtcc gttacttatc atactcaaat ggcgtgacat ttagaaggga
     8401 gaggaagatg aaaaaactga aattacggtt gacgcacctc tggtataagc tgctgatgaa
     8461 acttgggctg aaaagtgatg aagtctatta cataggcggg agtgaagccc tgccgcctcc
     8521 attatctaaa gatgaggagc aggttttgtt aatgaagctc cccaacggcg atcaggcggc
     8581 gcgagccatt ctaattgaac gcaatttgcg tctggtcgta tatatcgccc gtaaatttga
     8641 aaatacggga attaatatag aggatttaat cagcatcggt accatcggtc taatcaaagc
     8701 tgtgaataca ttcaatccag aaaagaaaat caagcttgct acctatgcct ctcggtgtat
     8761 agaaaatgaa atcctgatgt atttaagaag aaataacaaa atccgttcag aggtttcctt
     8821 tgatgaaccg cttaatattg attgggacgg caatgagctt ttgctttctg atgtgctcgg
     8881 cactgacgat gacatcatca ctaaagacat agaagctaac gtcgataaaa agcttctgaa
     8941 aaaagcgctt gaacagctta atgagagaga aaagcaaatc atggagctgc ggtttgggct
     9001 tgtcggtgaa gaagaaaaaa cccaaaagga tgtagcggat atgatgggga tttctcagtc
     9061 ttatatttcg cggcttgaga aaagaattat aaaaagattg agaaaagagt tcaacaaaat
     9121 ggtgtaaaaa attttatggt tagaacccct tgattttaca gggatttcct gatttcgaca
     9181 gtttttcggt ctgagtgcag tgcatatttt tcccacccaa ggagatactt aacgttgtac
     9241 agcagctcct gtagggaggg aaaaaagtgt cgagaaataa agtcgaaatc tgcggggtgg
     9301 atacctccaa attaccagta ctcaagaatg aagagatgag aaagctgttt aggcagctgc
     9361 aggatgaagg cgatgattca gcaagagaaa agcttgtaaa cgggaacttg cgtcttgtct
     9421 taagtgtcat tcaacgattt aataacagag gggagtatgt tgatgactta tttcaagtcg
     9481 gctgcatcgg actaatgaaa tccattgata attttgacct aagccacaat gttaagtttt
     9541 caacatacgc tgtacctatg attatcggag agatccgcag gtatttacgt gataataacc
     9601 cgatccgtgt ctcaagatca ctccgggaca tcgcttacaa ggcgcttcag gtaagagagc
     9661 ggttaatcag tgagacaagc aaggagccga ctgcagaaga catcgcaaaa gttcttgaag
     9721 taccgcatga ggaaattgta tttgcgcttg atgccatcca ggatccggtt tctctatttg
     9781 aaccgatcta taacgacggc ggagacccga tctatgtgat ggaccaaatc agtgatgagc
     9841 gtaatacaga ttcacaatgg attgaagagc tggctttaaa agagggcatg agaaggctga
     9901 acgataggga aaaaatgatt ttgagaaagc gattcttcca agggaaaacc caaatggaag
     9961 tcgccgagga aatcggaatt tctcaagcgc aggtgtccag acttgaaaaa gcggctatca
    10021 aacaaatgaa taaaaatatt catcaataat gaaaagcctt taaaacgatg ttgttttaaa
    10081 ggcttttcta ttgattacgg atggtttacg ttttgggaaa agtaaggtat cctagttcgt
    10141 acaaagtttt atgaaaatta aaacaattat aaaaggcaat aaagaggagg accacgatga
    10201 ttttgcagct tgacaatgtc tcactaaaac ggaatgggaa atggatactg agagatattc
    10261 attggaaggt ggaagaaaag gaaaattggg tgctttacgg cctaaatggc gccgggaaga
    10321 cagcgctgtt aaatatgctt tgctcttatt attttccaac atcaggcgag atgcaggtgc
    10381 ttggccatga atttggcaaa acagagcttg gggaaaagct cagacgtaaa attggcctcg
    10441 tctcagcagc tcttcagcaa aaattgtatc cggcagattc agcctttgaa attgctttga
    10501 gcggagctta cgcttcgatt gggttatatg aaacgccaag taagaaaacc agggaaaaag
    10561 cgattggttt gttagaggac ttgggagcaa ttgaatatgc cgatcgccgc tatgaaaccc
    10621 tttctcaagg ggaaaaacaa agagcattga ttgctagagc actaatggcc gatccggagc
    10681 tgctgatact ggatgaacca gtcacaggac tggattttat tgcccgggaa aagctgttag
    10741 atacgattac atacattgca aacaaagaaa atgcaccatc tatcctttat gtgactcatc
    10801 atgctgaaga aattttgcct gtctttgata aagccctttt attaaaacag ggagaggtct
    10861 ttggatccgg agaaataaag gaaatgctta ctaatcaaat actttccgct ttttttgata
    10921 cgccaatcca tgtattatgg aatcaagatc ggccgttttt aactagagct gagccgataa
    10981 cgaatgcctg acaaatatat atagattcat cctaggggtg ctttgcgaag ctgagagaga
    11041 cgttgtctca acccttttga cctgatctgg atcatgccag cggagggaag cggtgaaaag
    11101 cggagtacat cggactccgt ttgtttttat taagccgttt catcacattt gaaacggctt
    11161 atttgatttt aaagaatagg agcggattta cattggatca acaaatagac tctttgcaaa
    11221 aaaaagtgga agaacataag gaggagctta ttcagcttgc gaaaacgcta atttcttatc
    11281 aaacacctgc tccgcctgca agaaatacag agggcattca gtcatggatt gcgggatatt
    11341 taaatgaatt gggattctcg atcgacaaat gggatgtgta ccctggagat cccaatgttg
    11401 tagggaagct aaaaggaaca gattcagcag attattatag cctgattatc aatggccatg
    11461 tagatgtggc agaggtaaaa gaggatgaaa aatgggagca tgatccattt catccaattg
    11521 aaaaaaacgg tctcttaatc ggtcgaggcg cttccgatat gaagggcgga atggcttgtg
    11581 tgttgtttgc tgtcaaattg attcgtgaag caggcattga acttcccggt gatctgattc
    11641 tgcaatcggt tatcggggag gaagttggag aagccggcac gcttgaatgc tgcaagaggg
    11701 gctaccacgc tgattttgca attgtcgcgg atacgagcga tatgcatatt caaggccaag
    11761 gcggtgtcat tacaggctgg atcgaaatca aaagcagtca aacatttcat gatggaacga
    11821 gacggaatat gatccacgca gggggaggaa cattcggagc aagcgcaatt gaaaaaatgg
    11881 cgaaaatcat tgcggggctc ggtgaacttg agcgccactg gtctattatg aaaagttatc
    11941 ccggctttaa acctggaaca aatacaatta acccggctgt tatagaaggc ggcagacatg
    12001 cggcttttat agcggacgaa tgccggctgt ggatcacagt ccatttttat ccgaatgaaa
    12061 cccatgacca agtggcagcg gaaatagaag attacgtcaa tcggctgagt gacagtgata
    12121 tttggcttag ggaaaaccgc cctgtattca agtggggagg ctcatctatg atagaagaca
    12181 gaggagaaat ttttccggca ttggaagttg accctggcca cccaagcgtc ttagcgctaa
    12241 ctgcctctca tcagaaagtg aaacgggagt gtccaattat tgacgtttct caatcagtta
    12301 cagatggcgg atggctgtat gatgccggta ttccatgcgt aatatacggt cctggagatc
    12361 tgcacaatgc acactctgtg aacgagaagg tatcgattga gcagctagta gagtatacaa
    12421 aaattatact cgattttatc atcagctggt gcagccggaa aaaagagcaa tgacatgaaa
    12481 atttcttctt gctgacaagg ttcagcctgc ccgttcatat acttgaacaa aaggacggaa
    12541 aaaggacgtg atggaatgat cagcatttca gaatttcagg taaaggatgt cgtcaatgtc
    12601 tcaaacggaa aaaagctggg gagtattggt gatattgata tcaatgtgac cactggtaaa
    12661 attcaggcga tcatactagg aggaaatggg aaagttctcg gattttttgg aaaagaagag
    12721 gaattggtca ttccatggcg aaatatagta aaaatcgggg aagatgtaat cttggtccga
    12781 ttaagtgaac cacatgcata aacctgcttg tctgccgcag attggcaaat gccggaagtc
    12841 tcgattcttc cggcacattt catttagaaa tatgcaaatc ggcgctcaac gtatgcagta
    12901 agatgtggta aaataagtgg gaaattccgc ttttttaaat gtttgtcgaa aggttggatc
    12961 atcatgaata catatcaccc attcagtctt accacaccct cgacactcat gatacaagac
    13021 tgggctcaaa cgaatcaaaa caacaaagag gtcattgccg gatttacgac aaaaaacggc
    13081 ggtgtcagcc aaaagccttt tgaatcgtta aatacaggat tgcacgttca tgacaaagat
    13141 gcagatgtag ttaaaaatcg tgaatatatt gccgatatgt ttaatactga tttgcagtct
    13201 tgggtattcg ctgatcagac acatgataat cgcgttcaga aagtgacgca gagggatagg
    13261 ggaaaaggcg cccgtgagta tcacacggct ctaaaagcaa cggacgggct ttatacaaat
    13321 gaaaaaaatg tatttttggc attatgcttt gctgattgtg tgcctctttt cttttatgat
    13381 ccggttaagt cgcttgtcgg agtcgcccat gccgggtgga aaggcaccgt caaacagatt
    13441 ggcagagaaa tggtgaagca atggactgag aaggaaggtt caaatccctc agatatttac
    13501 gctgttattg gcccgtctat cagcggagca tgctatacgg tagacgaccg cgtaatggat
    13561 gctgtccgcg cattgccggt ttcagcagac cttgccgtta atcagacggc aaaggcacaa
    13621 tatcagcttg atctgaaaga gctgaaccgt cttatactga tggacagcgg tttggcaagt
    13681 gaacaaattt ctgtcagcgg tttatgcacg gaaagcgagc cgtctctttt ctattctcac
    13741 cgccgcgatc aggggaaaac tggacggatg atgtccttta tcggaatgaa ggaggcataa
    13801 aagatcttgc gtgttgttga taatttacga catataaacg aacgaataaa cgaagcatgt
    13861 aacagatcgg gccgcagctc cgatgaagtt acggttattg cagtcactaa atatgtatcg
    13921 cctgaaagag cacaggaggc agtagatgct ggcatcacct gcctcggaga gaatcgggat
    13981 gcggaactgc tccgcaaaca ggaattgata aaagggaatc cggaatggca ttttatcggc
    14041 agtctgcaat caagaaaagc aaaatctgtc gtcaattcgg tttcctatat ccattcccta
    14101 gaccggctct cattagcgaa agaaattgaa aaacgggctg aaggtactgt acgatgcttt
    14161 gtgcaggtca atacctctct tgagccttct aaacacggca tgaaaaaaga agaagtcatt
    14221 ccattcatac aggagctttc cggtttcgaa catatccttg ttgccgggct gatgacaatg
    14281 gctccgctga ctgatgatca agatcagatc agaagctgtt tcaggtcgct gagagaactc
    14341 cgtgaccagg ttcagaagct gaaccagccg aacgctccgt gtactgaact gtcgatgggc
    14401 atgtcaaatg attttgaaat tgcaattgaa gaaggagcta cttatattag aatcggctca
    14461 tcgttagtcg gaaatgaaac agggggtgta cagcaatgag tatgaaaaat aaactgaaaa
    14521 actttttctc aatggaagat gaagaatacg aatatgaata tattgagaca gagcgggaat
    14581 ctcatgagga gcatgagcaa aaagaaaagc cggcttatac ggggaataaa ccttcgggca
    14641 aacagaatgt agtgagcttg caaagtgttc agaaatcctc taaagtggtg ttgagtgagc
    14701 cgcgcgttta tgcggaggcg caggaaatag ccgaccattt gaagaaccgg cgggcagttg
    14761 tcgtcaatct tcagcggata caacatgacc aggcgaagcg gattgttgac tttttaagcg
    14821 gaaccgttta tgccattggc ggcgatattc aaagaatcgg ctcagatatt ttcctctgca
    14881 cgcctgacaa cgtagatgta tcaggcacaa tttctgagct catatctgaa gacgaacatc
    14941 agaggtggta aagcgagatg atcctttatc aagttttttc ggttttaagc ttattaatca
    15001 caatatactc atttgccctg atcatatata tttttatgtc atgggtgccg agtacgaggg
    15061 aaacagcagt cgggcgtttt ttggcttcga tttgtgaacc atatctcgaa ccattcagaa
    15121 aaatcattcc tccgattgca atgctggata tttcaccaat cgtagcaata cttgtgcttc
    15181 ggtttgcgac aaccggcttg tggggacttt atcgcatgat tgcgttttaa tgtgacagtt
    15241 tgataggggc ttggcagcag ccaagcctct ttacatagaa gggaaagacg atgagcgata
    15301 tatatcagca cttcagaaaa gacgagcggg cctttattga tcaagcgctc gaatggaaaa
    15361 gaattgtcca ggagcagtac aggatgaagc tgaccgactt tttagatccc cgagagcagg
    15421 tcatcctctc tgctgttacg ggacaggcag atgtcgggct tgccttttcc ggcggctatg
    15481 acagagcgga gcggaaacgg gcgattctgt atccagagta cattactccg gaagaatcag
    15541 attttgaact gcaggcgttt aacgtccgtt atgctgacaa gtttgtctca gtagatcatc
    15601 gttctctgct tggtgcatta atgggcatag gattaaagcg gcaaaaattc ggtgacatcg
    15661 tgttttctga gacagcagtg caattgattg tctcagccga taccgctgat tttgtggctg
    15721 cacagctgac ccaagcaggc aaagcggcgg tcagcctaga gaaaatcgac ttgtcagacc
    15781 ttaacattcc agcagttgat gtcgaaataa gagatgacac ggtttcttct ttaaggcttg
    15841 acgccgtctg cgcctctatg agcaggcaat cccgccagaa atcacagacg cttgtgaaaa
    15901 acggcctcgt gaaagtgaac tggaaggtgg ttgaagatcc ttcatacata gtcgcggaag
    15961 gggacatgct gtctatcaga ggttttggcc ggtgcagctt aacaaaaatc gaagggaaaa
    16021 ccaaaaaaga caaatggaga gttacgtttg aacgacaaaa atagtcggtt tttcagtttt
    16081 tttctccatc tgtgcgaaat ttgttttata atgtgaacta gataaccgta ctgaaatgta
    16141 aaaatggagg tggcatcatg ccattaacgc caaatgatat tcacaacaag acgtttacaa
    16201 aaagttttcg cggatatgat gaagatgaag taaatgaatt cctagcccaa gtcagaaaag
    16261 attacgaaat tgttctccgc aagaaaaccg agcttgaagc gaaagtcaat gagcttgatg
    16321 aaagaatcgg acactttgca aatattgagg aaacattgaa taaatcaatt ttagttgctc
    16381 aagaagcggc tgaagacgta aaacgcaatt ctcaaaaaga ggcaaagctg attgttcggg
    16441 aagcggagaa aaacgctgat cgcattatca acgaatcgtt atcaaaatca agaaaaattg
    16501 caatggaaat tgaagagctg aaaaaacagt ctaaagtgtt cagaacacgt ttccaaatgc
    16561 tgattgaagc tcagcttgat cttctgaaaa atgacgattg ggatcatctc cttgagtatg
    16621 aagtcgacgc tgtatttgag gaaaaggaat aaattctctg attatcttga cattttctta
    16681 gcttgtcgaa tataatacgt tcataaattc agatgaaaaa acggttgaaa gggacagtca
    16741 tgtttccttc aggccttcat agcgacccgg agatggtgag agtccgggat ggccggaatc
    16801 atgtagatca gccctttagt ttccttgctg aactcacagt aggttaggac gttcatcacg
    16861 ttacgatgct caagaggaaa aagtgtatgc ttgctttttc taaaagggtg gtaccgcgag
    16921 ataagctttc tcgtccctta tgggatgaga gggctttttt tattttctga aaaaatgcag
    16981 tggaggaatg aaaatggatt ttaaagacac gctcttaatg ccgaaaacag atttcccgat
    17041 gcgtggaaat ttgccaaacc gtgagcctga cattcaaaaa aaatgggagg aagaagatat
    17101 ctaccgtctt gttcaggaac ggacaaaaga ccgcccgaaa tttgttttac atgacggacc
    17161 tccgtatgca aacggcgaca tccatatggg ccatgcactt aacaagattt tgaaagactt
    17221 cattgtccgc tataaatcaa tgagcggcta caacgcaccg tatgtgccgg gctgggatac
    17281 acacggattg ccaattgaaa cagctctgac aaaaaacaaa aaggtcaacc gcaaagaaat
    17341 gtcagtagcg gaattccgca aactatgcga agagtacgct tggaagcaaa tcgagggaca
    17401 gcgtgagcaa ttcaaacgtc ttggtgtccg cggtgactgg gaaaacccat atgtgacatt
    17461 aaaaccggaa tacgaagcgc agcaaatccg cgtatttggt gaaatggcaa aacgaggcta
    17521 catttacaaa ggccttaaac cggttaactg gtcaccttca agtgagtctg ctctggctga
    17581 agccgagatc gaatatcaag ataaacgttc agcatctatt tacgtcgctt ttggtgtaaa
    17641 agacggaaaa ggcgttcttg aaaacggcga gcgcatcatc atttggacaa caacgccttg
    17701 gacaattccg gcgaacctcg gaatctcagt gcaccctgat cttgagtaca gcgtgattgc
    17761 agtaggtgaa gaccgctttg tcgtagcaag tgccttagtc gaaaatgttg catcggcatg
    17821 cggatttgat cagtatgaag tgacaagaac ggtcaaaggg aaagaccttg agaacattat
    17881 cgctgaacac ccgctatatg gcagagactc tctcgttatg cttggtgaac acgtaacaac
    17941 tgatgccgga acaggctgtg ttcatacagc gccaggacat ggggaagatg actttatcat
    18001 cggccaaaaa tacggtttag atgtgctttg cccggtcgat gaaaaaggtg taatgacaag
    18061 cgaagctcct ggctttgaag gcatgttcta tgatgatgca aacaaagcga tcacacagca
    18121 gctcgatgaa aaaggcgcac ttgtgaagct tgaattcatt actcactctt atccgcatga
    18181 ttggagaaca aaaaaaccaa ccattttcag agcgacagcg caatggtttg cgtctattaa
    18241 agatttcaga tcagacctgc tggatgccat taaagaaacc aaatgggttc ctgaatgggg
    18301 cgagcagcgt ttgcacaaca tggttcggga ccgcggagac tggtgtattt ccagacagcg
    18361 tgcgtggggt gtgccgattc cggtatttta cgctgaaaac ggagaaccga ttattacaga
    18421 tgaaaccatt gaacatgttt ctgaattgtt cagacagcac ggatcaaaca tttggtttga
    18481 aaaagaagca aaggatcttc ttccggaagg ctttacgcat cctggcagcc cgaacggcac
    18541 atttacaaaa gaacaggata tcatggatgt ttggtttgat tcaggctctt cacatcaagc
    18601 agtgcttgaa gaacgtgaag acctcgttcg cccggctgat ttatacctag agggatctga
    18661 ccaatatcgc ggctggttta actcttctct ttctacagca gtagccgtaa cagggaaagc
    18721 gccgtataaa ggtgtgctca gccatgggtt cgcactggat ggagaaggac gcaagatgag
    18781 taaatcaatc ggtaacgttg ttgttccggc taaagtcatg aaacagcttg gtgccgacat
    18841 cttaagatta tgggtatctt cagtggatta tcaggcggac gttcgcgtgt ctgacgccat
    18901 tctaaagcag gttgcggaag tatatcgtaa aatccgcaac acgttccgtt tccttcacgg
    18961 caaccttttc gattttgatc caaaaacaaa tgcggtggct gtcgaagatc ttcgtgaagt
    19021 ggatcagtat atgctgatta agctgaacaa gctgattgat aaagtgaaaa aagcgtatga
    19081 tgagtacgaa tttgcggttg tgtatcacag cattcataat ttctgcacaa tcgaattgag
    19141 ctcattctac cttgattttg caaaagatat tgtctacatc gagcatgcgg atcatccgga
    19201 tagacgcagc atgcagacag tattctacga aacgcttctt gcattagtga agctttcagc
    19261 gcctatcctt ccacatacgg cagacgaatt gtggtctcat ttaacatttg ttgaagagca
    19321 gagcgttcag ctgaccgata tgccggaaac aatcgcggtt ccaaacagtg aagcgactga
    19381 agaaaaattt gaccgcttta tggctcttcg tgatgacgtg ctaaaagcat tagaaactgc
    19441 gcgaaatgaa aaaattatcg gtaaatcttt ggaagctaac ctgaaattat atccaaataa
    19501 agaaaacaaa gagctcctgg cttccattaa agaaaatctt tctcagctgt ttattgtgtc
    19561 tgaactgaca atcagcgaag aaaatgaagc gccgaacgat gcgcaaagct ttgcgacagg
    19621 taaaatcgct gtcgagaaag cggaaggcga aatgtgtgag agatctcgtg tgatttcaaa
    19681 agatgtaggg gcaaatccga aatatcctac actttcatta cgcaacgctg aaatcgttga
    19741 aaaatactat caaaaataat gcaaaagagc tcggcgtaaa agccgggctt tttttgtgcc
    19801 aagagtgaca tcctttagaa cgacaggaaa aatcttatgg gctttagatc atcattcaca
    19861 ggcaacaata aggatactac gttaagagca ggagttgtga agaatgaatg atcaactgac
    19921 cgcaatttat acggaacttc ttctgatgaa agaagaatta cagtccagat tatttgagta
    19981 ttcttgcttt caggtttcta caagcccgca agcagcaatc aatcaaaaac aaaaagcaac
    20041 tctgatctat catattaaag aagaacttca agacgttctc cttgcattgt ccaaaatcga
    20101 aaacggcaca ttcggatact gtgaagaaac cggggctccc attcctcttg caaagctggc
    20161 agtgctgccg acggcccgaa cagcaaacga ttttctttat tctgtccaat ttgagaaaaa
    20221 aacgcttccg atatggaaat caacggatat cgaatatggt caggcactgt atgaataaca
    20281 gtgtctggcc ggttattatg cctgatattt ctttactcca gtgcttttta ttgataaaat
    20341 gcataatgga ttaaagtaac cgtaaactgg aggaacgttt gtgctgtatt atatgattgc
    20401 actacttatt attgcagccg atcaattgac aaaatggcta gttgttaaga acatggaact
    20461 tggccaaagc attccgatca ttgatcaggt attctatatc acctcccatc gcaatacggg
    20521 tgctgcatgg gggatattag cgggtcagat gtggtttttc tacctcataa caaccgctgt
    20581 tattattggt attgtttatt acatacagcg ttatacaaaa ggacaagggc ttcttggtgt
    20641 tgccctcgga cttatgcttg gcggtgccat cggcaacttt atcgatcggg ctgtcagaca
    20701 ggaagttgtg gattttatcc atgttattat tgtcaattac aattacccga tatttaacat
    20761 cgcggactct tcattatgtg tcggcgtaat gcttttattt atacaaatgc tgttggacag
    20821 cgggaaaaag aaaaaggagc aatagcatga atcaaattga tataaccgct tcagaagaac
    20881 aaaaaagtga gcggattgat aaatttttgg catcgactga gaatgattgg tcaagaaccc
    20941 aggttcagca atgggtaaaa gacggacagg ttgtcgtgaa cggaagcgcg gtgaaagcga
    21001 attataaaat tcagccgggt gatcaggtga ccgtcactgt acccgaaccg gaagcgctcg
    21061 acgtcctggc agagcctatg gatctggata tttattatga ggaccaggat gtgctggtcg
    21121 tcaacaaacc tcgcggaatg gttgttcacc cagcacccgg gcatcttacg ggcacacttg
    21181 taaacggcct tatggctcat tgcacagacc tttccggaat aaatggcgtg atgcgtccgg
    21241 gtattgttca cagaatcgat aaggacacgt ccggcttatt aatggtggcg aaaaatgata
    21301 tggcacacga gtcacttgta aatcaattgg tcaacaaaac ggtcacacga aagtatacgg
    21361 cggttgtcca cgggcttatt tctcatgatg acggcacaat tgacgcgccg atcggacggg
    21421 ataaaaaaga tcgtcaaagc atgactgtga cacgtgatgg caaaaacgct gtcactcatt
    21481 ttcatgtgct tgagcgtttt caggatttta cgttagtgga atgccagctt gaaacaggga
    21541 gaacccatca aattcgtgtt catatgaaat atatcggatt cccattagca ggcgatccga
    21601 aatatggtcc gagaaaaaca atcgacttta acggccaggc tctccacgcg ggagttttag
    21661 gttttgacca tccacgaaca ggagaatatg tcgaatttga agcgccgctt cctgaggata
    21721 tggcagaatt aatcgaaaac ctcagaaaaa acggttgaca gagggtttct tttctgaaat
    21781 aataaacgaa gctgaataga ttctttaaaa cagtccagag aggctgagaa ggataacgga
    21841 tagacgggat gcgtgtatag tgcgcacctt gtcctaaaac ccctctatgc tctggcagga
    21901 ggggtttttt cttctatatg aactgtgagg tgtcacacat tgaatcaaaa agctgtcatt
    21961 ctcgacgaac aggcaattag acgggcgctg accaggattg ctcacgaaat gatcgaacgc
    22021 aataaaggaa tgaataactg cattcttgtc ggtattaaga caagggggat ttacctggca
    22081 aaacgccttg cggaacgcat tgaacagatt gagggaaatc ctgttacagt cggtgaaatt
    22141 gatattactc tttacagaga cgatctttct aaaaaaacga gcaacgatga acc
//
