LOCUS       gnlProkkaGLKDKGKL_41   14901 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GLKDKGKL_41.
ACCESSION   gnlProkkaGLKDKGKL_41
VERSION     gnlProkkaGLKDKGKL_41
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 02:28:02
            Original ID  :: gnl|Prokka|GLKDKGKL_41
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14901
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14901
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[5092:5992]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5093..5992
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..14901
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14901
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     CDS             complement(2..1882)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 110.9; E-value:
                     1.4e-33)"
                     /gene_kind="transport"
                     /locus_tag="ctg41_1"
                     /transl_table=11
                     /translation="MGRESLYYCSGNAFPGMIQWFFDIPSKLIHWRLNLVRALGAYVPW
                     LRRDDGSMKVHAGTLVDLFATILSGRRHLSARDADAALDILRYTFPEVEHRWLSNRFER
                     SMRASLTVADVLASAASGRDETERMAIALEVLSLLINTGDSRMTGELFDQVTYGLELPG
                     TANHLRQLLMTPDVEAQEPAYSVGFSSGIGAEVSLPEQDKGISFRLIRCSRLVLVVNDG
                     TRPIVVRGRHLQPGGVMPLTNGQVVLLPSGPLSFEDFAFFLDCKRSGKQEVCYISLDGG
                     SLQISRVRSRASEVRVNMGLACEVEVLRPEVEFAVDGRRLYPGESVRMAYYSSFTLDGE
                     GPFSMGEVQNSMSDIGRRFRLDPGNRKLRVTNLPEKARKGDMLLTPGLAPGAVLEVSFS
                     SATNSGWLEVVEASMPLLLNGRPVRGRVSLRDGDVVHLNAYHALRCRFSAGVLDEEYHA
                     IRTLSVEGVTKEFLRSGRVLDNIDLTVKRGEMVCILGPSGSGKSTLLSMLAGQLPPTRG
                     CIRYNNQLLYSAPDLIRPYIAFIPREDILDAAMSVSEHISQATMIRRPRLSRSERVRRV
                     NAILKFLGLTHIASRRVGEMNARTISDGERTRLNLGLDLAGIADVFLLDEP"
     CDS             2026..2448
                     /locus_tag="ctg41_2"
                     /transl_table=11
                     /translation="MDILVSTLCDFAADYQGKLCIQGGFDSLVARQFPVVHPVCAVALR
                     ICLTPEDEGTHELGLSIVDADGTPLDKERMPIKINFPVPAFPEGASFFTRNLIMNFQGL
                     RFEKPGNYSIDLTVDGELASRVPFRVVQVQEEAAQA"
     CDS             2684..3529
                     /NRPS_PKS="Domain: PKS_KR (11-174). E-value: 5.6e-14.
                     Score: 44.3. Matches aSDomain:
                     nrpspksdomains_ctg41_3_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     160.7; E-value: 7.2e-49)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_3"
                     /sec_met_domain="adh_short (E-value: 9.5e-33, bitscore:
                     103.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHTARLQYDRIIITGASSGFGEAFAGTLAPHTAELVLIARNEAAL
                     RQLAAALEKRHSGLHASVLPCDLADEASLNMLISRLDSLPPGRTLLINNAGAGDYGDFS
                     DGRWEKIRFLLRLNVESLTRLCHALVPSMKRNGGDIINLSSLGALLPIPDFAVYAATKA
                     YVSSLSEALRLELREHGIRVLAVCPGPVSTGFGKAARRPGFTGNMMPGRNAFDTSVETV
                     VKDSLRALARGRARVFPGMKIRLAAMLLAAAPLGLIRLFMGRRPRKVLPASNDSPSSAS
                     "
     aSDomain        2717..3205
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg41_3_PKS_KR.1"
                     /evalue="5.60E-14"
                     /label="ctg41_3_PKS_KR.1"
                     /locus_tag="ctg41_3"
                     /protein_end="174"
                     /protein_start="11"
                     /score="44.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="IITGASSGFGEAFAGTLAPHTAELVLIARNEAALRQLAAALEKRH
                     SGLHASVLPCDLADEASLNMLISRLDSLPPGRTLLINNAGAGDYGDFSDGRWEKIRFLL
                     RLNVESLTRLCHALVPSMKRNGGDIINLSSLGALLPIPDFAVYAATKAYVSSLSEALRL
                     "
     CDS             3526..5091
                     /locus_tag="ctg41_4"
                     /transl_table=11
                     /translation="MKAHRRRIPRLTWFKLAVCICLAAMAASLFTPYPAQIIRALKGGA
                     GFRNLSAPEIPPTEQPGQEEQPITAAPSASGKEPGDERLYTPWTPERTIALPPVQYPPF
                     PPVLPTRPAEGAMTHIYELARGLNLKTQVNFQPGTLASRDRETKSNYQMTLSLNVKQPK
                     ALTKKEDMLKLNPKLEPMLPGLSTLFRHARVSPYYGQIYVRKQTEIRKNLASLLKLLDR
                     HNYYDTETILETTYPDTGRKLLWLQSEMDVVSDGSDGDRLAAMPDKILKSSFYQPSTSY
                     RWKKRTDKPNPLLKPWQQRLASYKKTLEKAPAAEKTALRRKIDHAERVIEELKRYSFLI
                     SEYDPFIVVPLGVVNQSTPFSPQFGDYAVVIVGDKLYPALVGDAGPRYKTGEGSLRLSR
                     EINPKAGPYSRPVSDLKVSYLIFPGSAEPEAGPPDYEKITDRCRELLNEIGGVGKGFNL
                     HQWEDLLAPKPPPAPKPESGGTAETPADKRKKEEAPGNKPAPAPAPPASPQTAPASSAA
                     KSAA"
     CDS             complement(5093..5992)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_5"
                     /sec_met_domain="phytoene_synt (E-value: 1.9e-18, bitscore:
                     56.2, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGLDHLLSAVSRSFYLSMRFLPREMRPGVAVGYLLARATDTVAD
                     AVDMDCRERLALLRMMGETVAGSASREVAATCFGRLGVLSTIQTHRGEAELLARFPECL
                     ALLENLSPHERMLVRQVLASIVEGQAWDLMYFESHAAVSCPEQLEHYTYMVAGCVGEFW
                     TRLGLLAQGPGFSTQPEEQLLRWGRHYGMGLQLVNILRDREEDLARGRSYLPAPDDRPW
                     LDRAERWLKEGVFYAESLRNGRLRFSTVLPAWLGLDTLELLQRADRRHPSSGKVKIARG
                     DVYLRMWKAFLFSWKEAL"
     CDS             complement(5989..7515)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 426.4; E-value:
                     2.4e-129)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg41_6"
                     /transl_table=11
                     /translation="MNEINRSPDLEMVVLKEISSAIVNERNGTALLRHILDVLYRRMKM
                     LRGTFTIRRGNDLMIEASHGLDEQEMKRGHYHVGEGITGHVAETGRPHVIEDISRDSRF
                     LNRTRTRKSGEKVAFICVPIIHLQQVIGTLSIDRAVDRDTDLERDQKLLEIVGNIVGDA
                     LAASLQAHEERAALVAENEKLRELLTTNPGELIGNCSTMLQVYEQIRQVAPSDATVLIR
                     GSSGTGKELVARAVVNLSGRKDKPLVTLNCAAMPENLLESELFGHEKGSFTGATSRRIG
                     RAEAADGGTLFLDEIGDLSLQMQVKLLRFLQEKTFSRVGSNRELHADVRFIAATSRNLE
                     ELMAASKFREDLYYRLNIFPIVMPDLSKRKGDVMLLAEHFLSKFNLKYGKDIKRLSTPA
                     INMLMAYHWPGNVRELENCMERAVITAQDDCIYGYNLPASLQMPSHDVPYSRDGEAPAD
                     LPTMVDSFERELIVAALKRSPGNMSAAARELGISPRVLHYKMHRLGLQKS"
     CDS             complement(7713..9500)
                     /locus_tag="ctg41_7"
                     /transl_table=11
                     /translation="MNSPLPQSQPPDSVWYGWILKLFHHWKVGERQVTYVWAVLVGMVG
                     SCMSLFFEWMVEVIQWMLTGIWSDSRVGTFSLVEPEWRMFIPVAGGLVAGCILLFLKKR
                     MPGQATEYMEAMSIGNGLIKFRASALKVFSAAWSIASGAAIGKEGPIIQSSALIASTVG
                     QHLHVSIPRLRLLVGCGAAAGFTTAFHAPFSGCLFVSEIIIGTVSMDILAPLLIASCTG
                     FVMLHLLGDPSPLYSSPFESFSVFSQSLWCIALGAAAAVAARGWVSLLDAAARYLNGRQ
                     SLLPLRLAAAGLVVGILAVFYPEVVGNGQALITGLVHEDYGTREALVLLLVKVSAVAVV
                     FGCGTVGGAMTPTLYVGSMVGFIFSTVLTSLGMEGNHTVAYAMVGMASFFAVAAQAPLT
                     ALVMVVEFSMSGQMIYPLLIGVVSAYGTGKLIRARSMYAASLAGSPASVVNLPMAQVHV
                     HDLARHVVPQVAPDASLDDVSSLMLRNPGDLVFVVNKDGIYEGAIYPEDFLAVRRQMEV
                     RKGAVPADAGALVRTGAPVLDAGTHLTDALKLFEQTHLPAFPVVWKNTGRLDGVLYRNA
                     LFQVITEMMKRESGGDVGM"
     CDS             complement(9671..10465)
                     /locus_tag="ctg41_8"
                     /transl_table=11
                     /translation="MTNMKMNTVILLSLAACTGMLACPGAWATAVCQEQSYHLKTACPH
                     PLSLAGPADERVYLRFQAGWASKYECEGLDLWDGSLCMFVPEIQYKEWVGKIWYGVSTD
                     HRNHAELKYRLDYVRELGNWTVMPWYEHSFVFPGDKGIPRPGLKTTYHFSDRWFGGADL
                     YWQYNNHTFRGYYAVFAGMHEEIADCVRVDAVVRYGYNGGYVGPVVHHGSNALDYNLSV
                     TFRATGRLTVELFTNYSQALTVVKQKGLGDDFYYGVNLKYTF"
     CDS             10687..12684
                     /locus_tag="ctg41_9"
                     /transl_table=11
                     /translation="MKFIIPALALSACLPAAFSQEQIIPKPAEITLFTGSPARLTPDSL
                     IITETQDKAFLDQAGQLQQMLSAGTGLPLPLKPAGQASKKAACIVIKKDPALAARGEEA
                     YSIQSSPSGIILSAADARGIFYAGQSLVQMMPSVFHDRTADKSAVRWNISETPFRITDY
                     PRFTWRALMIDEARHFFGEKTIKQIIDQMALLKMNILHWHLTDDTGWRIEIKKYPRLTS
                     IGSKRRESEIGTWNSGKSDGTPHEGFYTQEQIRDIVQYAARRNITIVPEIEMPGHASAA
                     AVAYPFLSLKTPGEVPTTFIVNTAFDPTSEKTYAFLSDVLDEVTAIFPGRIIHIGGDEV
                     RYDKQWKGVPEIEEFMKKNGMKSYADVQMHFTNRMSGIIAQKGRRMMGWNEIYGHDVNG
                     DGGGKAGAKLDTNAVIQFWKGNTSLAKNAIRDGHDVINSLHTSTYLDYSYGSIPLQKAY
                     GFEPVFPGLEEQYQSRVKGLGAQVWTEWISTPERLHYQAFPRACAFAEVGWTPAGKKDF
                     PDFKKRLKAYSERMDLMGIKFARNVISQIDKSDFFNTPMIGTWTPATLTREEHSFDVTK
                     LVKASGKHTVTLLYDKGAHAIEIESVALYENSREVSRDAHAGRSGAHKENIQYILNAPA
                     PRQGATYTVKANFKGAGGRDSHGTVYFETP"
     CDS             complement(13024..13530)
                     /locus_tag="ctg41_10"
                     /transl_table=11
                     /translation="MVSLSGICLLKGETVPQKTEWKGGRLIYDGVIIKNQFNLPQKGIK
                     YHDEDRLSYDVMDTTIEMSTTLSKNPQCGREWCYKGISHIVVKYSGPISDPIDGGTIYF
                     EPYYNHHIWFDKKKYGEWGILYSKVYIITRIKNANIEDVRDYGISGEDGSIFFQYVEKV
                     VDDNM"
     CDS             complement(13557..14900)
                     /locus_tag="ctg41_11"
                     /transl_table=11
                     /translation="MLGSDAHAGKNIVFRGEDWTTKGDWCGKYGHTRATLCATNAPMSN
                     SEFKAKPIKFRTLSSVPGHPGYKGALSPYWIQGLMGLNRKKGDALRWWVHSIKENDNRN
                     VLFDPTDSVRTEAEWDDHGEVYPGFVDGPDIWVAVEVPEGVHEIALYFYNPNGYLTNES
                     RRDYVVEARRHPSTAPLVFQFNIEGDLAIGEQNNWGKELAASMEQWYSYPVEARTRVSR
                     FAGSGVYKRFMSRKGGIYLFRICRNGSFNTILNGVFVNEKIPWEIRIPEELPYYVSGAL
                     AGIVPTPERVSGATLGQREKAVCKPLYELQYTRKYLTPAACSLQNRYILSLWRQARKSR
                     AEGGCLADCLQWEARVSDDRVRASFDETMKRSWEQSQIYYIGNRSRDFMPNAPGTVPFS
                     LSELRLMAKLRIDWRQYRDDAKTPPEKTVQEMKEFLNKELLKQQQSRK"
ORIGIN
        1 taggttcgtc cagcaggaaa acatccgcaa tgcccgccag gtcaagcccc aggttcaggc
       61 gtgtgcgctc cccgtcggaa atggtgcggg cgttcatctc acccacgcgg cgggaggcga
      121 tgtgcgtcag gcccagaaat ttcaaaatag cgttcacgcg cctgacgcgt tccgaccggc
      181 tcagccgcgg acgacgtatc atggtggcct gagagatgtg ttcggaaacg ctcatggccg
      241 catccagaat atcttcccgg ggaatgaagg cgatgtaggg ccggataaga tccggggcgc
      301 tgtacagaag ctggttgttg taacggatgc agccccgggt gggcggcagc tggccggcca
      361 acatggagag cagcgtgctt ttcccggatc cgctgggccc caggatgcac accatttccc
      421 cgcgtttcac ggtcaggtca atattgtcca gcacgcgccc ggagcgcagg aattccttgg
      481 tcaccccttc cacgctgagg gttctgatcg catggtattc ttcatccagc accccggcgg
      541 aaaaacggca gcgcagcgcg tggtaggcat tcaggtgcac cacgtcccca tccctcaggg
      601 aaacccttcc ccgaacaggc cggccattga gcagcagagg catggaggcc tccaccactt
      661 ccagccagcc ggaattggtg gcgctggaaa aagaaacctc cagcaccgct ccgggggcca
      721 gaccgggagt cagcagcatg tctcccttgc gcgccttttc cggcaggttg gtcacccgca
      781 gtttgcggtt tccgggatcc aagcggaaac ggcgcccgat gtccgacatg gaattctgca
      841 cctctcccat ggagaaaggc ccttccccgt ccagcgtgaa ggaggagtaa taggccatgc
      901 gcacgctttc accggggtac agccgtctcc cgtcaaccgc gaattccact tccggcctca
      961 gcacctccac ctcgcacgcc agccccatgt tcacgcgcac ctcgctggcg cgggaacgca
     1021 cccggctgat ttgcagggag ccgccgtcca gggaaatata gcatacttcc tgcttgcctg
     1081 aacgcttgca gtccagaaaa aacgcgaagt cttcaaaact cagcggaccg gacggcagca
     1141 gcaccacctg cccgttggtc agcggcatca ccccgccggg ctgcaaatgg cgcccgcgca
     1201 ccacaatggg gcgggtgccg tcattcacca ccagcaccag gcgggaacac cggatcaggc
     1261 ggaaggaaat gcccttgtcc tgctccggaa gggatacctc cgcaccgatg ccggaggaaa
     1321 aaccgacgct gtacgccggt tcctgggctt ccacgtccgg cgtcatcagc agctgcctca
     1381 ggtggtttgc cgtgcccggc agttccagac cgtacgtcac ctggtcaaac agctcccctg
     1441 tcatgcggga atctcccgta ttgatcagca gggaaagcac ttccagagct atcgccatgc
     1501 gttccgtctc atccctgccg gaagctgcgg aggccaggac atccgcaacc gtcaggctgg
     1561 ccctcatgga ccgctcaaaa cggttggaaa gccagcggtg ctccacttcc gggaaagtat
     1621 agcgcagaat atccagagcg gcgtccgcat cacgggcgct caaatggcgg cgtccgctca
     1681 aaatagtggc gaacaagtcc accagcgttc cggcatgcac cttcatggag ccgtcgtcac
     1741 ggcgcagcca cggcacgtag gcgcccagcg ccctgaccag attcagcctc cagtgaatca
     1801 gcttggaagg aatgtcaaaa aaccattgga tcatgcccgg aaacgcgttg ccggaacagt
     1861 agtacaggga ttcccgcccc atctcaagcg caaccggaat ttcacggaga aatgacaata
     1921 ttttctacag ctttatcttg caataggtcc agaggaagta tagttctgtc caatgttcat
     1981 gctttccgcg tgaaagctag ccaaatacat caacattatc acaacatgga tattttagtt
     2041 tctactcttt gtgacttcgc cgccgactac cagggcaagc tctgcattca gggcggcttt
     2101 gactccctgg tcgcccgcca gttcccggtc gtgcatcccg tctgcgccgt tgccctgcgc
     2161 atctgcctca ctcctgaaga cgaaggtaca cacgaactgg gcctgagcat cgttgatgcc
     2221 gacggcacgc cgctggacaa ggaacgcatg cccatcaaga tcaatttccc ggttcccgct
     2281 ttcccggaag gagcctcttt ctttacccgc aacctgatca tgaacttcca gggcctgcgt
     2341 tttgaaaaac cgggcaacta ctccatcgac ctgacggttg acggcgaact cgcctctcgc
     2401 gtacccttcc gcgtagtgca ggtgcaggaa gaagccgccc aggcctaaga aaccatcccc
     2461 tcttccatta aaccgcctcc cgttcatccg gcaggcggtt ttttattgga gcggccgtcc
     2521 gcccggaagt gcggaacagg ccggccccgg ttccatgcac ctgaaaacct ctgcgcctgg
     2581 ccccggccta aaaaagggag accggctttt tgcgtcctcc ttcccccttt ttcattgcgg
     2641 ttccgcaccg gattgaccat gatacgggct gctccaaccc gccatgcaca ccgcacgcct
     2701 ccaatacgac aggattatca ttacgggcgc atcatccggc ttcggggaag cgtttgccgg
     2761 aacgctggcc ccccatacgg cggaattggt gctcatcgcc cggaatgaag ccgccctgcg
     2821 ccagcttgcc gccgccctgg aaaaacgcca ttcaggcctt cacgcctccg tccttccctg
     2881 cgaccttgcg gacgaagcct ccctgaatat gctcatttcc cgcctggaca gccttcctcc
     2941 gggaagaacc cttctgatta acaacgccgg tgccggtgat tacggagatt tctcggacgg
     3001 ccgctgggaa aaaattcgtt ttctgctgcg cctgaacgtg gaaagcctca cccgcctgtg
     3061 ccatgcgctg gtcccctcca tgaagaggaa cggaggagat atcatcaacc tcagctccct
     3121 gggagccctc ctgcccattc cggattttgc cgtttatgcg gccaccaagg cttatgtttc
     3181 cagcctgtcg gaagcgctgc ggctggaact gcgcgaacac ggcatacgcg tgctggccgt
     3241 ctgcccgggc ccggtttcca cgggtttcgg aaaagcggcg cgccgccccg gctttaccgg
     3301 aaacatgatg ccggggcgca acgcttttga cacgtccgtt gaaaccgtcg tgaaagacag
     3361 cctccgtgcc ctggcccgcg gacgcgcccg ggtctttccc ggcatgaaaa tacgactggc
     3421 cgccatgctg ctggccgccg cccctctggg gctgatacgc cttttcatgg gcaggcgccc
     3481 ccggaaagtc ctgccggcat ccaatgattc tccttcttca gcatcatgaa agcgcaccgc
     3541 cgcagaatac cccgcctcac ctggttcaag ctcgcagtct gcatctgcct ggcagccatg
     3601 gcagcctccc tgttcacgcc gtaccccgcc cagatcatac gcgccctgaa agggggcgcc
     3661 ggattccgga acctgtccgc cccagaaatc ccccccacgg aacaacccgg gcaggaagaa
     3721 cagccaataa ccgctgcacc atccgcctcc ggaaaggaac ccggggatga acggctgtac
     3781 actccatgga cgccggagcg cacaatcgcc ctccccccgg tgcagtaccc cccatttccc
     3841 cccgtgcttc ccacaaggcc cgcggaaggg gccatgaccc atatttatga actggcccgc
     3901 ggcctgaacc tgaaaacgca ggttaatttc cagcccggca ccctggcctc cagggacagg
     3961 gaaaccaaaa gcaattacca gatgaccctt tccctgaacg tcaaacagcc caaagcattg
     4021 acgaaaaagg aagatatgct gaagctcaat ccgaaactgg aacccatgct tcccggcctg
     4081 tccaccctgt tcaggcatgc gcgcgtctcc ccttactacg ggcagattta cgttcgcaaa
     4141 cagacggaaa tccgtaaaaa cctggcctcc ctgctcaaac ttctggaccg ccataattat
     4201 tacgatacgg agacgattct ggaaaccacc tatccggaca cgggaaggaa gcttctctgg
     4261 ctgcaaagtg aaatggatgt tgtttccgac ggctcggacg gggaccggct ggccgccatg
     4321 ccggataaaa tcctgaaaag ctccttctat cagcccagca cttcctaccg ctggaaaaag
     4381 cgcacagaca agcccaatcc cctgctcaaa ccctggcagc agaggctggc ttcctacaag
     4441 aagacgctgg aaaaagcccc cgccgcggaa aaaacggctc tgcgccgcaa aatagaccat
     4501 gcggaacggg tcattgagga actgaagcgg tacagcttcc tgatctcgga atacgatccg
     4561 ttcatcgtgg ttccgctggg agtcgtcaac cagtccactc ccttctcccc gcagttcggg
     4621 gactatgccg tcgtcatcgt gggagacaag ttgtacccgg ccctggtggg agacgccggg
     4681 ccgcgctaca aaaccgggga gggttccctg cgcctgagcc gtgaaatcaa ccccaaggcg
     4741 ggcccttaca gccgccccgt ctccgacctg aaggtaagtt acctgatttt ccccggttcc
     4801 gcagagcccg aggccgggcc tcccgactat gaaaaaatta cggacagatg ccgggaactt
     4861 ctcaacgaaa taggcggcgt ggggaaagga ttcaacctcc accagtggga agacctgctg
     4921 gcgcccaagc caccgcccgc cccaaaaccg gaaagcggcg gcacagcgga aacacctgca
     4981 gataagcgga aaaaggagga agctcccgga aacaagcctg cccctgcccc ggctccgccg
     5041 gcttccccgc aaactgctcc ggcttcatca gccgcaaaaa gcgccgcata agctacagag
     5101 cctctttcca agaaaaaaga aaggctttcc acatccgtaa ataaacgtct ccgcgcgcaa
     5161 tcttcacctt cccggaagac ggatgccgcc gatccgcccg ctggagcagt tccagcgtgt
     5221 ccagccccag ccaggcgggc aggacggtgg aaaaacgcag ccgcccgttc cgcagagatt
     5281 ccgcgtaaaa cacgccttcc ttcagccagc gttccgcgcg gtccagccat ggacggtcat
     5341 ctggggcagg caaatagctt cttccgcggg cgaggtcttc ctcccggtca cgcaggatat
     5401 tcaccaactg cagccccatg ccatagtgcc tgccccagcg caaaagctgc tcctccggct
     5461 gcgtgctgaa gcccggcccc tgggccagca agcccagcct ggtccagaat tcccctacgc
     5521 atccggccac catgtaagta taatgttcca gctgttccgg gcatgagacg gcagcatggc
     5581 tttcaaaata catcaaatcc cacgcctgtc cctccacgat ggaggccagc acctgccgca
     5641 ccagcatccg ttcatgcggg gaaaggtttt ccagcagcgc caggcattcg gggaaacggg
     5701 ccagcaattc cgcctccccc cggtgcgtct ggattgtgga aagaacgccc agacggccaa
     5761 aacaggtggc ggcaacctcc cgggaggcag agccggccac cgtctccccc atcatcctca
     5821 aaagcgccag gcgctcccgg caatccatgt ccacggcatc cgccaccgta tccgtggcac
     5881 gcgccagcag atagcccacg gccacgccgg ggcgcatttc ccggggcagg aagcgcatgc
     5941 tcagataaaa ggaccgggag acggccgata aaagatggtc aaggcctttc atgatttctg
     6001 caggcccagc ctgtgcatct tataatggag tacccgcggg gaaatgccca gttcccgggc
     6061 cgcggcggac atattgcccg gagaacgttt caatgcggct acaatcaatt cccgttcaaa
     6121 ggaatctacc atggtcggca aatcggcggg agcctccccg tcacgggaat aagggacgtc
     6181 atggctgggc atctggaggg aggcgggaag gttgtaaccg taaatgcagt cgtcctgcgc
     6241 cgtaatgacg gcacgttcca tgcagttttc cagctcccgg acgttgccgg gccagtggta
     6301 agccatgagc atgttgatgg cgggggtgga cagccgtttg atatcctttc cgtatttcag
     6361 gttgaacttg gaaagaaaat gttccgccag cagcatgacg tcccccttgc gtttggagag
     6421 gtccggcata acgatgggga aaatgttcaa ccggtagtac aagtcttccc ggaacttgct
     6481 cgccgccatc agttcctcca gattgcggct ggtggcggcg atgaagcgca cgtctgcatg
     6541 aagctccctg ttgcttccca cgcgggaaaa ggtcttttcc tgaagaaagc gcagcagctt
     6601 cacctgcatc tggaggctta aatccccgat ttcatccaga aacagggtgc cgccgtccgc
     6661 cgcctccgcc cggccgatgc ggcggctggt ggccccggta aaagaaccct tttcatgacc
     6721 gaacagctcg ctttccagca ggttctccgg catagccgca caattcagcg tgaccagcgg
     6781 cttatccttt ctgccgctca gattcaccac ggcgcgcgcc accagttcct tccccgtccc
     6841 ggaacttccc cgtatcagca ccgtggcatc gctgggcgcc acctggcgga tctgttcata
     6901 cacctggagc atagtgctgc aattgccgat caattcgccc ggattagtcg tcaaaagctc
     6961 ccgcagtttt tcattttccg cgaccagggc ggcacgttcc tcatgcgcct ggaggctggc
     7021 agccagagca tccccaacaa tattgcctac aatctccagc agtttctgat cccgttccag
     7081 gtcggtgtcc cggtccacgg cacggtcaat gctcaacgtg ccgataacct gctgcaaatg
     7141 aatgatggga acgcagatga aggctacttt ttcaccgctt ttgcgcgtgc gggtacggtt
     7201 caggaacctg gaatcccggg aaatatcctc aatcacatgg ggcctgcccg tttccgccac
     7261 atgccccgta atgccttccc ccacatggta atggccgcgt ttcatttcct gctcgtccag
     7321 gccgtgggag gcttcaatca tcaaatcgtt cccgcggcgg atggtgaacg tgccgcgcag
     7381 cattttcatg cggcggtaaa gcacgtccag aatatgccgg agcaaagccg tgccgttgcg
     7441 ttcattgaca atggcggagc tgatttcttt cagcacgacc atctccaaat ccggtgacct
     7501 gtttatttca ttcatgcaat ccggggctgg gcgaatatta accgcacgcc cccgccatac
     7561 caactacttt ttcttccacc gccatgcacc cggacaaaaa aacggcacgg ggaatatgga
     7621 taacatccca gcaattaatg ttgatgatat tacgaacggg gaacaaaaga tttttacaaa
     7681 aatgtaatac acatcccttg tctcgttccg ttttacatgc ccacgtctcc gccggactcc
     7741 cgtttcatca tctccgtgat aacctggaac aacgcgttgc ggtacagcac gccgtccagc
     7801 cgaccggtat tcttccagac cacgggaaag gcgggcagat gggtttgttc aaacagcttc
     7861 aaggcatccg tcaaatgggt gccggcgtcc agcacgggag cccccgtacg gaccagggcc
     7921 ccggcatcgg ccggaaccgc ccccttccgc acctccatct gccggcggac cgccagaaag
     7981 tcctccggat agatggcccc ttcataaatt ccatccttat tcaccacaaa aaccagatct
     8041 ccgggattcc gcagcatcag ggaggagaca tcatccaggg aagcatccgg ggccacctgg
     8101 ggcaccacgt gccgcgccag gtcatgcaca tggacttgcg ccatgggcag gttgacgacg
     8161 gacgccggac tgccggccag gctggcggca tacatggaac gcgcgcgaat cagttttccc
     8221 gtgccataag cgcttacgac accgatcagc aagggataaa tcatctgtcc gctcatggaa
     8281 aactccacta ccatcaccag ggccgtcagg ggggcctggg cagctacggc gaaaaaggat
     8341 gccatcccca ccatcgcata cgccaccgta tggttgccct ccattcccag ggacgtcaga
     8401 accgtactga agataaaacc caccatgctc cccacgtaca gggtgggcgt catggctccg
     8461 cccaccgtac cgcagccgaa caccaccgcc acggcagaca ccttcaccag aagcaggacg
     8521 agcgcctccc tcgtgccgta atcctcatgg accagcccgg taatgagagc ctgaccgttg
     8581 cccaccactt ccggataaaa aacggccaga atccccacga ccagcccggc ggccgccaaa
     8641 cgcagcggca gaagggactg gcggccattc aaatatctgg cggccgcatc cagcaaactg
     8701 acccatcccc tggccgccac ggccgccgcc gcccccaggg cgatgcacca gagagactgg
     8761 gaaaagacag aaaagctttc aaacggggaa ctgtacaaag gggagggatc ccccagcaga
     8821 tgcagcatca cgaacccggt acaggaggca atgagcaggg gggccagaat atccatgctc
     8881 acggtgccga tgatgatttc actcacgaac aggcagccgg aaaaaggggc atggaacgcc
     8941 gtcgtgaacc cggctgccgc tccgcagccg accagcagcc ggagccgcgg aatggatacg
     9001 tgcagatgct gccccacggt agacgcaatc agggcggaag actggatgat aggcccttcc
     9061 tttccgatgg ccgcgccgga agcgatgctc catgccgcgg aaaaaacttt cagggcggag
     9121 gcccggaact tgatcagccc gttcccgatg gacatggcct ccatgtattc cgtagcctgc
     9181 cccggcatcc ttttcttcag gaacagcaga atgcagccgg ccaccaggcc gcccgccacc
     9241 ggaataaaca tgcgccattc cggctccacc agggaaaagg ttcctacgcg ggaatccgac
     9301 cagatgccgg tgagcatcca ctggatcact tccaccatcc actcgaaaaa cagagacatg
     9361 caggagccca ccatgccgac gagcacggcc catacataag taacctgcct ttcccccacc
     9421 ttccaatgat ggaacagttt taaaatccat ccgtaccaga cggaatccgg cggctgggac
     9481 tgggggagtg gagaattcat agaaaagaag gcaatactat tccattgtga caaaaaaata
     9541 cctccggctg ttcgatacgg aagaaaaaac tgcccagccc catgcccctc cggagccaga
     9601 gaagattttc aacggatacg cagacggctc ttacgggccc cccttcgggg cctggccccc
     9661 gcgccggtgg tcagaacgta tatttcaaat tgacgccgta atagaaatca tcccccaacc
     9721 ccttttgctt taccacggtc agcgcctggc tgtaattggt gaacaattcc acagtcaggc
     9781 gcccggtagc acggaaggta acgctcaggt tataatccag agcattggaa ccatggtgca
     9841 ccaccgggcc tacatacccc ccattgtaac cgtagcgcac tacggcatcc acccgcacgc
     9901 aatcagctat ttcttcatgc atccccgcaa atacggcata ataaccgcgg aacgtatggt
     9961 tgttatactg ccagtacagg tccgcgccgc caaaccagcg gtcggaaaaa tggtaggtcg
    10021 ttttcaatcc gggacgcggg attcccttat ctcccggaaa aacaaagctg tgctcatacc
    10081 agggcatgac cgtccagttg cccaattccc tgacgtagtc cagccggtat ttcagctccg
    10141 catgattccg gtggtccgtg gaaacgccgt accatatttt ccccacccac tctttatact
    10201 gtatttcagg aacaaacatg cagagagaac cgtcccacaa gtccaagccc tcgcactcgt
    10261 acttgctggc ccaccccgcc tgaaatcgca aataaacacg ctcatccgca ggaccggcca
    10321 gggaaagggg gtgggggcat gccgtcttca ggtggtagga ctgttcctgg cagaccgccg
    10381 tcgcccaggc tccgggacac gccagcatgc cggtgcaggc cgccagcgac aacagaatta
    10441 cggtattcat cttcatattg gtcatggctg gaaatttttc tgaaacggca tatccggaag
    10501 cggcgccatc cacccatgca tacccgcatc ccgctttagc cgtaaacgga tactacgccc
    10561 tcacccggac aaataccttc taaagatgag accagcatga aaaaacaata ttcagttcca
    10621 agagccaaaa aaacgaattc cccatgaaag attgtgtcag tagtctttgt acctataacc
    10681 gtgtccatga aattcattat ccccgcactc gccctgtccg cctgccttcc cgcagccttc
    10741 tcacaagaac aaatcatccc gaaaccggcg gaaatcacat tgttcacagg aagtccggcc
    10801 cgtctcacac cggattccct catcatcacg gaaacacagg acaaagcttt cctggatcag
    10861 gcagggcaat tgcagcagat gctcagcgca gggacgggac tcccccttcc ccttaaaccg
    10921 gccgggcaag cgtcgaaaaa agccgcctgc attgtcatca aaaaagaccc agccctggcc
    10981 gccaggggag aagaagccta ctccatccaa tcatccccaa gtggaatcat cctttccgca
    11041 gccgatgcca ggggcatctt ttacgcgggg caaagcctgg tccagatgat gccctccgtc
    11101 ttccacgacc ggacggcgga taaatccgcc gtccggtgga atatttctga aactccgttc
    11161 cgcataacgg actacccgcg gttcacctgg cgggcgctga tgattgatga agcacgccac
    11221 ttctttggcg agaaaaccat taaacagatc atcgaccaaa tggctctgct gaaaatgaac
    11281 atcctgcact ggcacctgac ggacgacaca ggatggcgca ttgaaatcaa gaagtatccg
    11341 cgcctgacct ccatcggctc caaacgcagg gaatcagaaa tcggcacatg gaacagcggc
    11401 aagtcagacg gaacgccgca tgaaggcttt tatacccagg aacagatcag ggatatcgta
    11461 caatacgcag cccgccgaaa catcaccatc gttccggaaa ttgaaatgcc gggccatgcc
    11521 agcgccgccg ccgtagcata ccccttcctg agcctgaaaa ctcccgggga agtgcccaca
    11581 acattcatcg tcaatacggc cttcgatccc acctcggaaa aaacttatgc cttcctgtcc
    11641 gatgttttgg atgaagtcac ggcgatcttc cccggcagaa tcatccacat tggcggagat
    11701 gaagtgcgct atgacaagca atggaagggt gttccggaaa ttgaggaatt catgaaaaaa
    11761 aacggtatga aaagttatgc ggacgtccag atgcatttca ccaaccgcat gtccggcatt
    11821 attgcccaaa aagggcgccg catgatggga tggaatgaaa tttacggaca tgacgtcaat
    11881 ggggacggag gaggaaaagc cggcgccaaa ctggatacaa acgccgtcat ccaattctgg
    11941 aagggcaaca ccagcctggc taaaaacgcc atccgggacg ggcatgacgt tatcaattcc
    12001 ctccacacct ccacctattt ggattacagc tacggcagca ttcccctgca aaaggcatac
    12061 ggattcgaac ccgttttccc cgggttggag gaacagtacc aatccagagt caagggactg
    12121 ggcgcccaag tatggacgga atggatttcc acaccggaac gcctgcacta ccaggcattc
    12181 ccccgtgcct gcgcctttgc ggaagtcggc tggactcccg ccggtaaaaa ggattttccg
    12241 gatttcaaaa aacgcttgaa agcgtatagc gagcgtatgg atctgatggg gatcaagttt
    12301 gcccggaacg tcatcagcca aatagacaaa tctgactttt tcaatacgcc catgatcggc
    12361 acatggacgc ctgccaccct gacccgggag gaacattcgt ttgacgttac caaactggtc
    12421 aaagcgtccg gcaaacacac cgtcaccctg ctgtacgaca aaggcgccca cgccatcgaa
    12481 atcgaatccg tagccctgta tgaaaattcc cgggaagtct cccgggacgc ccatgcaggc
    12541 agaagcggcg cccataagga aaatatccag tacattctga atgccccggc ccccaggcaa
    12601 ggagcaacct atacggtcaa agcaaacttc aaaggggccg gaggccggga ttcccacggg
    12661 acagtgtatt ttgaaacgcc ataaaaacac cgcccccgcc ccataccaga aacagcaggg
    12721 ggggcttcac acagagcccc ctttactcca acaaacggag cacagcatcc gcagactcat
    12781 ggttacggac acgagccttt cagtatcatt ggcctcccaa gggcgccggc atgtcttttc
    12841 atagaggaag acgccccttt ccatcaggtg gcacgaaatt gatactttaa cccacagaaa
    12901 ggcttaccct gaaatcagcc ttgccttaac aaggctccgg aggtcgttgc ttgcgaacct
    12961 ccggaacctg aacaaccgtg aatcggcgga agatgatttt catccgggaa agccagacgg
    13021 aatttacatg ttatcatcta ccactttttc cacatactgg aaaaagatgc ttccgtcctc
    13081 cccgctgatt ccatagtctc tgacatcctc aatattcgca ttcttgattc gggtaataat
    13141 atagactttg gagtacaaaa tcccccattc cccatacttt ttcttatcaa accagatatg
    13201 gtggttatag tatggttcaa aatagatggt gcctccgtct atcggatcgg aaatcgggcc
    13261 ggaatatttg acaacaatat ggctgattcc cttgtaacac cattccctgc cgcattgagg
    13321 atttttggaa agggtggtgc tcatttcaat ggtggtgtcc atgacatcat aggacaacct
    13381 atcctcatca tggtatttga ttcctttttg aggcagattg aactgatttt tgatgatgac
    13441 tccatcataa atgagacgtc cccctttcca ttccgtcttc tgcggcactg tttccccttt
    13501 caagagacag attcctgaga gagaaaccat tattgcacag gcaattttat tcattgttat
    13561 tttctacttt gttgttgttt cagcaattcc ttattgagga attctttcat ttcctgaaca
    13621 gttttttcag gaggggtctt cgcatcgtcc cgatactgcc tccagtcgat gcgcagcttg
    13681 gccatcaggc gcaattcgct gagagaaaaa ggaacagtac ccggggcatt cggcatgaaa
    13741 tcccgggacc tgttgccaat ataataaatc tggctctgct cccaagaacg cttcatggtc
    13801 tcatcgaagg aagctctcac acggtcgtcg cttactctgg cttcccactg gaggcagtcc
    13861 gccaggcaac caccctcggc ccgactcttc cgggcctgcc gccacaggga aagaatatac
    13921 ctgttctgaa gactgcacgc agccggagta aggtacttgc gcgtatactg caactcatac
    13981 agaggcttgc acacagcctt ttccctctgt cccagagtag ctccactcac cctttccgga
    14041 gtggggacaa taccggccag agcaccggat acgtaataag gcagttcctc aggtattcga
    14101 atttcccacg gtattttttc attcacaaac acgccgttta aaatggtatt aaaggaaccg
    14161 ttccggcaaa tacggaacag gtaaatcccc cctttcctgc tcatgaacct tttataaacc
    14221 ccggaccccg caaatctgga aacgcgtgtg cgcgcctcca ccgggtagga ataccactgc
    14281 tccatggatg cagcaagttc cttcccccaa ttattctgtt ctcctatcgc aagatccccc
    14341 tcaatattga actggaacac aaggggagcg gtggaagggt gccttctggc ttccaccacg
    14401 taatcccgcc tggattcatt ggtgagataa ccgttgggat tgtaaaaata cagggctatt
    14461 tcatggacac cttccggcac ctctacggct acccatatat cgggtccgtc cacaaagccc
    14521 ggatacactt ctccgtggtc atcccactcc gcctctgtcc gcacggaatc cgtagggtcg
    14581 aaaagaacgt tgcggttatc attttccttg atgctgtgca cccaccagcg caaagcgtcc
    14641 cctttcttgc ggttgagccc catcagcccc tgaatccagt agggagacaa ggcccccttg
    14701 tatccgggat gtccgggaac ggaagaaaga gtacggaact taataggctt ggctttgaat
    14761 tcggaattgc tcatgggggc attcgtggcg cacagcgtgg cacgcgtgtg cccgtacttc
    14821 ccgcaccagt ccccttttgt agtccagtcc tccccccgga acacaatatt cttccccgca
    14881 tgcgcatcgg accccagcct t
//
