LOCUS       c00041_gnlPro..        14405 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JFLGNBBN_41.
ACCESSION   c00041_gnlPro..
VERSION     c00041_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:01:33
            Original ID  :: gnl|Prokka|JFLGNBBN_41
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 27417
            Orig. end    :: 41822
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14405
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[37417:40175]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12758
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..14405
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14405
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(1095..2576)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_aromatic"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_27"
                     /sec_met_domain="Lyase_aromatic (E-value: 4.7e-190,
                     bitscore: 623.2, seeds: 479, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHHHITAEHLSVGRVREILERRLPLALSDDARARIVRCREYLDR
                     KMENPERPIYGITTGFGSLCDISVGRDELSRLQQNLVMSHACGTGERVPSEIVRLILLL
                     KIQSLAYGHSGVQLATVERLVEFFNRGILPVVYQQGSLGASGDLAPLAHMSLPLLGLGE
                     VEYKGEVRPSAEVLAELGLEPIRLQSKEGLALLNGTQFMSAYGVWSLIHARRLSEWADR
                     IGALSLDAFDGRIEPFCDEVHLIRAHRGQLATARNVRRLLEGSELIVRPKHHVQDPYSF
                     RCMPQVHGASKDTIDYVESVLTTEINSTTDNPTVFPEEDMVVSAGNFHGQPIALAMDFL
                     AIALAELGNISERRTYKLISGARELPKFLVANPGLNSGFMIPQYTAASIVSQSKGLCMP
                     ASVDSIPSSQGQEDHVSMGSNAATKLWRVVCNTERVLAIELFNAAQAIEFRRPAHTSPE
                     LERLLADYRKEVPFIDNDEVMYPHIEASVRFLRGL"
     CDS             complement(2608..4647)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_28"
                     /sec_met_domain="Urocanase (E-value: 1.6e-90, bitscore:
                     293.5, seeds: 148, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_C (E-value: 1.1e-90, bitscore:
                     293.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_N (E-value: 1.7e-60, bitscore:
                     193.6, seeds: 71, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTREEFQNDIRAGIPDRLPAAKPYDKRINHAPKRKDILSDEEKTL
                     ALKNALRYFPVRHHAVLAKEFAEELRRYGRIYMYRLRPDYEMHARPIGEYPARCRQAAA
                     IMLMIQNNLDPRVAQHPHELITYGGNGAVFQNWAQYRLAMQYLSEMTENQTLVMYSGHP
                     LGLFPSHPDAPRVVVTNGMVIPNYSKPDDWERLNALGVSQYGQMTAGSYMYIGPQGIVH
                     GTTITVMNAARKRFTAGRTDTRGMLFVSSGLGGMSGAQPKAGNISGVVSVVAEINPKAA
                     QKRHEQGWVDELHEALDELIPRIRQAVKAKEVVSMAYVGNVVDLWERLAAEEIPVDLGS
                     DQTSLHNPWAGGYYPVGLSYEASNKMMAEEPGRFRECVQESLRRQVDAINKLTDRGMYF
                     FDYGNAFLLEASRAGAAVTGEGGRFRYPSYVQDIMGPMFFDYGFGPFRWVCTSGKPEDL
                     ETTDSLAAEVLEEIRKTAPDDIRGQLDDNIHWIREAGRNRLVVGSQARILYADCEGRVK
                     IAEAFNRAIAEGRITAPVVLGRDHHDVSGTDSPYRETSNIYDGSCLTADMAVQNVIGDA
                     FRGATWVSIHNGGGVGWGEVINGGFGMVIDGSEDAGRRIREMLLWDVNNGIARRSWARN
                     EGAVEAIRREMDRTPGLRVTLPVFADEELVREALNEQGGASDKL"
     CDS             complement(4649..6349)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTCD_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_29"
                     /sec_met_domain="FTCD_C (E-value: 1.7e-66, bitscore: 214.6,
                     seeds: 242, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQRIIECVPNFSEGRDKAVIRQITAAIEASGGVKLLDVDPGEAT
                     NRTVVTFVGEPEAVVEAAFAGVKRAAELIDMRRHKGAHPRMGATDVLPLIPIAGVTLAE
                     CAELARALARRIADELRIPTYCYEAAAFAPERKNLAVCRAGEYEALPEKLAHTASAPDF
                     GARPFDEGVARTGATTVGARDFLIAVNFNLNTTSTRRANAIAFDVREKGRPVREGNPIT
                     GRVVKDAAGNPVMQPGTLPATKAIGWFIEEYGIAQVSMNITDISRTPLHAAFDEVCRKA
                     DARGVRVTGTEIVGLVPKRALVEAGKYFLRKQRRSTGVAEEEIVRIAVKSMGLDDLKPF
                     DPAEKVIEYLLEAEVPKKRLIDMTCKAFAEETASESPAPGGGSIAAYMGALGAALGTMV
                     ANLSSHKAGWDDRWEEFSDWAERGQAVLAELLHLVDEDTAAFNRIMAVFAMPKSTDEEK
                     AARAAALQEATLYATEVPLRTMKAASRVFEIVRAMASEGNPNSVSDAGVGALAARSAVL
                     GACLNVKINAAGLKDRAVADALTAEADALAAEAVRLEAEVLQIVESKIG"
     CDS             complement(6538..8520)
                     /locus_tag="ctg41_30"
                     /transl_table=11
                     /translation="MENIQTKQYPCFKRWSRKNWSVFASLHRYVTIGVLSVGMSILLLA
                     TQGASAQTADTTAVLKTLRIREVGVTGSQTAPARNAQSHTPLFDRKAQAPAPVQTLEAA
                     LRLAPSVDVRERGGKGTQADIFIRGGSFDQTMVLLNGIDFTDARTGHQSHALPVDLDCI
                     SAVELIDGVPGVGAYAGAVNIRTAPLRPTYLRLEASGGQYGYGYGNLSGAVSAGRFSVL
                     GAASYRRSDGYRHNTDFSNYNAFVRATYDGGRAGFFDLQAGWQDRDFGSNGFYAAYNPD
                     QWEHTATALGSLRWLKTAGRFSLGAAASYRKNFDRYDWTRGTAMNRHNTDNVGAKLWAD
                     CDWAAGVTTVGGDYAFNHIYSTNLGDKLSVPEGHYTHAKARHTGNLWLRHAKRWRHFDA
                     AASAGVSLTPYGTSALWSLSAGYAPAAGLRLEAGAWQSMRLPTFTDLYYTSPAQINNLD
                     LTPEHAVTYRLGVDYLKRSWNLSAQAYYRSGRDIIDWVWREDMGSKWHSEQTSSLDTFG
                     IELAGGYTVSEGFLRRVTLSYGYITTDRNADVIAKSAMDFMRHKAALAVEVHFLRRMSL
                     ALTGSVYDRNGSYTHYPEPGNASLNEERDYKPYFLLDGRLQWEKGICRLYVDATNITDT
                     RYCDIGGIRLPGFWCTGGVTLTIGK"
     CDS             complement(8675..9967)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_31"
                     /sec_met_domain="PALP (E-value: 5e-28, bitscore: 89.5,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENFTPTPYTLECVATGREFEDAGWMLADPQCKEPSLVRTKYARK
                     QIDVKPADWGLYRFSDWMPVRRILKGSSAPVTYKSKGLAAHLGLENLWITFNGWYPAIG
                     ATMSTCSFKETEAYSVCGRAAADERRVLVVASAGNTARAFAKVCSDNNIRLLLSVPYDN
                     IGALWFDQPLNPCVKLISCEKGGDYFDAIHLSDIALKSPGFYAEGGAKNVARRDGMACT
                     VLSAVTTIGRIPDYYFQAVGSGTGAIAAWEANMRLVEDGRFGRNTMKLMVAQNAPFVPM
                     YDAWQAASRKLLPYDDDKARRDAEIIDAKVLSNRRPPYSVTGGLFDALKATGGEVFVAT
                     NAMARKARKLFHELEGVDIYSAAGVALASLVNAVNAGKIEKDATVMLNVTGGGEEHFKE
                     GKELWYLKPSHVFPLEPDEADVVEKVEALFN"
     CDS             complement(10001..11140)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_32"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 3.1e-11,
                     bitscore: 34.7, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDFLKLPSPCYVLDEELLDRNLATVDRVRRESGAEIIVALKACA
                     MWSIFPELAKHSDGATASSAAEARLVFEEFGRPAHTYAPVYTDSNIDEILNCSDHITFN
                     SLSQFRRFGQKALINGISCGLRINPQYSPVETDLYNPCVPGSRLGVTAEQLAAHGGLPA
                     GVEGLHFHVLCESRPEHLQKALEAVETHFGAYLDRIKWLNMGGGHLMTASWYDCDRLIA
                     LLKAFRSRHPNLRLILEPGSAFTWRTGFLVSTVEDIVENGGVTTAMLDVSFACHMPDCL
                     EMPYKPAVIGAHEPADGEKRWRMGGTSCLAGDYCGDWAFDRELKVGERVVFEDMIHYTM
                     VKTTMFNGVHHPSIVIARRDGRTDVIREFGYEDFRNRMS"
     CDS             11145..11531
                     /locus_tag="ctg41_33"
                     /transl_table=11
                     /translation="LFLVGFHPSFSPLGIIRASPALPSLNENVQNSCKSSKNLLKTTLR
                     RLGFRENTHLYLSLAKPGPEISIGAGRRQGHFGKSGSAENDTTVLILEERKIPLRFSIG
                     AVHLSCIVKNPRMGRTSALSIRGF"
     CDS             complement(11568..12758)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_34"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 3.5e-39, bitscore:
                     126.6, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 9e-36, bitscore:
                     114.2, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCKALIIGAGGVGTVVTQKIAANPVFTDVMLASRTKSKCDAVAAA
                     IGGNRVKTAEVDADSVPQLCELFRAFKPDIVVNVALPYQDLTIMDACLECGCNYLDTAN
                     YEPKDEAHFEYSWQWAYQDRFKAAGLTAILGCGFDPGVTAIFTAYAAKHHFDEIHYLDI
                     VDCNAGNHGMAFATNFNPEINIREVTQKGRYYENGEWVVTEPHEIHKPLNYPGIGERES
                     YVIYHEELESLVKNYPTIRRARFWMTFGQEYLTHLRVIQNIGMARIDPIIYNGVEIVPI
                     QFLKAVLPDPKSLGANYHGQTSIGCRIKGLKDGKERTYYIYNNCDHEQAFKETGTQAVS
                     FTTGVPAALGASMWAKGLWRGAGVFNVEEFDPDPFLAELGEQGLPWHELFDVNLEV"
     CDS             complement(13205..14155)
                     /locus_tag="ctg41_35"
                     /transl_table=11
                     /translation="MLGESEVLSRDKTAAGVELDVCIPALRAAVEPGSWYWHRNLVERD
                     REKRLLCERKGIRLITVYDHYDETAVPFDDCLVTPCDLASRRNMDKLVAVTKTLLGAFG
                     LDSNLAAGEWETIRRRAELDSRRMTTEEFRAELAGINDKIEVIGEYTRASDKIRVRCKV
                     CNHEWSVAPTTLRRGSGCASCAGRLKLTHERFVERLNLLHPEIVPLTEYVNSQTRMTFE
                     CRACGHVWSAQAYGLIAKSRSSGCRKCSVWAMLRRRSRKVRCITTGEVFDTLREAAAKY
                     GVSRSAISQCCSEPPKLKRAGGREWEYVDLLSGER"
ORIGIN
        1 gctcaacccc atggcatagg cgccgttgag cgtcgcggcg ttgatcgcct cggcgggggt
       61 catcttcatg cggatcgagg ccagcgaaca gaccatgcgc atgttgcccg agggcgacga
      121 cccggggttg tagtccgaag ccagcgccac gcccagcccg gcgtcgatca tcgcgcgcgc
      181 cggaggatag ctcatcccga ggaagaacgc cgcgcccggc agcagcgtcg gcatggtcgc
      241 cgcgccgcgc agcgcctcga tctcctcccg tcccatgcgt tcgaggtggt ccaccgacag
      301 ggcgtcgcag gccacgccca cctgcacgcc gcccgagacg gccagttcgt tggcatggat
      361 tttcgcccgc agccccagtt tgcgcgcggc tttgagaata cgggccgtct cttcgaccgt
      421 gaaaaaacct tcgtcgcaga agacgtcgac gaaatcggcc agcccttcgg ccgccacggc
      481 gggcagcatt tcgttgcaca ccagatcgac atactccccc tgccgtcccc ggtaggcacg
      541 cgccacggca tgcgccccga ggaacgtggc ccgcacctcc agcggcacgc tttcgcggat
      601 gcggcggatg acgcgcagca tcttcagctc gtccccggtc gaaaggccgt agccgctctt
      661 gatctccacg caccccgtac ccatcgccgc gatctcgcgc acgcgttcca tcgcctgcgc
      721 atagagttcg tcctccgaag tctcgtgcag ccggtcggcg gagttgagaa tgcccccgcc
      781 ccgccgggcg atctcctcgt acgacaaacc gttgatcttg tccagaaact cccgctcacg
      841 gctcccggcg tagaccaggt gggtgtgcga gtcgcagaac gacggaaaga gcatgccccc
      901 tgccgcgtcg acgacctcgt cggcggcgat gtcgcccaga gagtccatgc gtccgaacgc
      961 cgcgaaacgg ccgtcttcgg ccagcagcca cgcgtcgtcg agcgtgtcca gcttgttcat
     1021 gtcggcgccg cagcagcgca gacggcccgt cgattcgatg ccgacgatgc gggcgatgtt
     1081 cttcaccagc agtctcatag gccgcggagg aatcggacgg aggcttcgat atggggatac
     1141 atcacctcgt cgttgtcgat gaagggaacc tctttgcgat agtcggccag caatcgctcc
     1201 aactcgggcg acgtgtgcgc cgggcggcgg aactcgatgg cctgcgcggc gttgaacagc
     1261 tcgatggcca gcacccgttc ggtgttgcag accacgcgcc agagcttcgt ggcagcgttg
     1321 gaacccatgc tcacatggtc ctcctgcccc tgcgacgagg ggatcgaatc gaccgacgcg
     1381 ggcatgcaca gccccttgga ctggctcacg atcgacgccg cggtatactg cggaatcata
     1441 aagccgctgt tcagcccggg gttcgccacg aggaatttgg gcagttcgcg cgccccggag
     1501 atcagtttgt aggtgcgacg ctcggagatg ttgcccagct cggccagggc gatcgccagg
     1561 aaatccatcg ccagagcgat cggctgtccg tggaaattgc ccgccgagac gaccatgtcc
     1621 tcctcgggga agaccgtcgg attgtccgtc gtggagttga tttccgtggt cagcacgctc
     1681 tccacatagt cgatcgtgtc cttcgaggct ccgtgaacct gcggcatgca gcggaacgaa
     1741 taggggtcct gcacgtggtg cttggggcgg acgatcagtt cgctgccttc gagcagccgg
     1801 cggacattcc gggccgtggc gagctgcccc cggtgggcgc ggatcaggtg cacctcgtcg
     1861 cagaaaggct cgatacgacc gtcgaaggcg tctaacgaca acgccccgat gcggtcggcc
     1921 cactcgctca gccgccgggc gtggatcagc gaccagacgc cgtaggcgct cataaactgc
     1981 gtgccgttca gcagcgcaag gccctctttc gactgcaacc ggatcggctc cagccccagt
     2041 tcggcaagca cttcggccga gggacgcacc tcgcccttat actccacctc gcccagcccc
     2101 agcagcggca ggctcatatg tgccagcggc gcgaggtcgc ccgaagcgcc cagcgaaccc
     2161 tgctgataga cgacgggcag gatgccgcgg ttgaaaaact ccacgagacg ctccaccgtc
     2221 gccagctgca cgcccgaatg gccgtaggcg agcgactgta tcttgagcag cagaatcagc
     2281 cgcacgatct ccgagggcac gcgctccccg gttccgcagg cgtgcgacat cacgaggttc
     2341 tgttgcaggc gcgacagctc gtcgcggccc accgaaatgt cgcacagcga cccgaaaccg
     2401 gtcgtgatgc cgtagatcgg ccgctcgggg ttctccatct tgcggtcgag gtactcgcgg
     2461 cagcggacga tgcgcgcccg ggcgtcatcg ctcaacgcga gcggcagccg ccgttcgagg
     2521 atttcgcgga cgcgcccgac cgaaaggtgc tccgcggtga tatggtgatg ttccatggat
     2581 gacaattcaa aattcataat tcgaaattca taatttatcc gaagcgccgc cctgttcgtt
     2641 cagcgcctcg cggacaagtt cctcgtcggc aaaaacaggc agggtcacac gcagtccggg
     2701 cgtgcggtcc atttcgcggc ggatggcttc gacggctcct tcgttacgcg cccagctgcg
     2761 gcgcgcgatg ccgttgttga cgtcccacag cagcatttcg cggatgcggc ggccggcatc
     2821 ctccgaaccg tcgatcacca tgccgaagcc gccgttgatc acctcgcccc agcccacgcc
     2881 gcctccgttg tggatcgaaa cccacgtcgc gccgcggaac gcatcgccga tgacgttctg
     2941 cacggccatg tcggccgtca ggcacgaacc gtcgtagatg ttcgaggtct cgcggtaggg
     3001 cgaatcggtt cccgaaacgt cgtgatggtc gcgccccagc accacgggag ccgtgatgcg
     3061 gccctcggcg atggcccggt tgaacgcctc ggcgatcttc acgcgccctt cgcagtcggc
     3121 atagagaatg cgcgcctgcg acccgacgac cagccggttg cgcccggcct cgcgaatcca
     3181 gtggatattg tcgtccagct gcccccggat gtcgtcggga gccgtcttcc ggatctcctc
     3241 cagcacttcg gcggccagag agtcggtcgt ttcgaggtct tcgggcttcc ccgaggtgca
     3301 gacccagcgg aacggcccga agccgtagtc gaagaacatg ggtcccataa tgtcctgcac
     3361 gtaggagggg tagcggaagc gtccgccctc gcccgtcacc gcggccccgg cgcgcgaggc
     3421 ttccagcagg aaggcattgc cgtagtcgaa gaaatacatt cccctgtcgg tcaatttgtt
     3481 gatggcatcg acctgccgcc gcagcgactc ctgcacacac tctctaaagc ggcccggctc
     3541 ctcggccatc atcttgttcg acgcctcgta gctcaacccc acgggatagt aaccgcccgc
     3601 ccaggggttg tgcagcgagg tctggtccga acccaggtcg accggaatct cctccgcggc
     3661 cagccgctcc cagaggtcca cgacgttgcc cacataggcc atcgacacga cctctttcgc
     3721 cttgacagcc tgacggatac gcggtatcag ctcatccagc gcttcatgca gctcgtcgac
     3781 ccatccctgc tcgtggcgtt tctgcgccgc cttggggttg atctcggcga cgaccgacac
     3841 cacgcccgaa atattgcccg ccttgggctg cgctcccgac atgccaccga gacccgacga
     3901 gacgaacagc atcccgcgcg tatcggtgcg gccggccgtg aagcgtttgc gcgcggcgtt
     3961 catcaccgtg atcgtcgtac cgtggacgat gccctgcggc ccgatataca tgtacgaccc
     4021 ggcggtcatc tgcccgtact gcgacacccc gagggcgttg agccgctccc agtcgtcggg
     4081 tttcgagtag ttgggaatca ccatgccgtt cgtaaccacc acgcgcggag cgtcgggatg
     4141 cgacgggaac agccccagcg gatgcccgga atacatgacc agggtttgat tttcagtcat
     4201 ttccgaaaga tactgcatcg caaggcggta ctgcgcccag ttctggaaca cggcgccgtt
     4261 gccgccgtag gtgatcagct cgtggggatg ctgggcgacc cgcgggtcga ggttgttctg
     4321 aatcatcagc atgatggccg ccgcctgccg gcagcgggcg ggatattcgc cgatcggacg
     4381 cgcatgcatc tcgtagtcgg gacgcaggcg gtacatatag atacggccgt agcggcgcag
     4441 ctcctcggcg aactccttcg ccagcacggc gtggtgcctg accggaaaat agcgcagggc
     4501 gtttttcaga gccagcgttt tctcctcgtc cgaaaggatg tccttgcgtt tgggcgcatg
     4561 gttgatccgt ttgtcatagg gtttcgcggc gggcagccgg tcgggaatac ccgcgcgaat
     4621 gtcgttctga aactcttcgc gtgtcatatt atccgatttt agattcgacg atctgcaaga
     4681 cctccgcttc gagacgcacg gcttcggcgg ccagcgcatc ggcctcggcg gtcagcgcat
     4741 cggccacggc acggtccttc agccccgcgg cgttgatctt cacattgagg cacgccccca
     4801 gcaccgcgct gcgggccgcc agcgcaccca cgccggcgtc ggagaccgaa ttggggttgc
     4861 cctccgaggc catggcgcgc acgatttcaa aaacccgcga ggcggccttc atcgtccgca
     4921 gaggaacctc cgtggcatag agcgtcgcct cctgcaaagc cgcggcgcgc gccgccttct
     4981 cctcgtcggt cgacttgggc atggcgaaaa ccgccatgat gcggttgaac gccgccgtgt
     5041 cctcgtccac gaggtgcaga agctccgcaa gaacggcctg cccccgttcg gcccagtcgg
     5101 aaaactcctc ccagcggtcg tcccaccccg ccttgtgcga cgaaaggttg gcgaccatcg
     5161 tcccgagggc cgcgcccagc gcgcccatgt aggccgcgat cgagccgccg cccggagcgg
     5221 gagattcgct cgccgtctct tcggcgaacg ccttgcaggt catgtcgata agccgcttct
     5281 tcggaacctc cgcttcaagc aggtactcga tcaccttctc ggcaggatcg aacggcttca
     5341 ggtcgtccaa tcccatcgac ttgacggcga tgcggacgat ctcctcctcg gcgacgcccg
     5401 tcgagcgacg ctgcttgcgg aggaagtatt tgccggcttc gaccaaagcc cgtttcggaa
     5461 ccagccccac gatttcggtc cccgtgacgc gcacgccgcg ggcgtcggcc ttgcggcaca
     5521 cctcgtcgaa agccgcgtgg agcggcgtcc gggagatgtc ggtgatgttc atcgagacct
     5581 gcgcgatgcc gtactcctcg atgaaccagc cgatggcctt cgtggccgga agcgttccgg
     5641 gctgcatcac gggatttccc gcggcatcct tcaccaccct gcccgtgatg ggattgccct
     5701 cgcggacggg acgccccttt tcgcgcacgt cgaaggcgat ggcgttggcg cggcgcgtgg
     5761 aggtggtgtt caggttgaaa ttcacggcga tcaggaagtc gcgcgccccg acggtcgtag
     5821 ctcccgtgcg ggcgaccccc tcgtcgaagg gacgcgcccc gaaatcgggc gcggatgccg
     5881 tgtgcgccag tttctcgggc agggcctcgt actccccggc gcggcacacg gcgaggtttt
     5941 tccgttcggg cgcaaaggcc gcagcctcgt agcaataggt cgggatgcgc agttcgtcgg
     6001 cgatacgccg ggccagcgca cgcgccagtt cggcgcactc cgcaagcgtg acgcccgcaa
     6061 tcggtatcag cggcagcacg tcggtggccc ccatgcgggg atgcgccccc ttgtggcggc
     6121 gcatgtcgat cagttcggcc gcccgcttca ctccggcaaa agcggcctcg acgaccgctt
     6181 cgggttcgcc gacgaaggtc acgaccgtgc ggttggtcgc ctcgccgggg tccacgtcga
     6241 gcagtttgac gcccccggag gcctcgatgg ccgcggtgat ttgccggatc acggccttat
     6301 cgcgtccctc gctgaaattg ggaacgcatt caatgattct ttgggacata ggatcgtcgc
     6361 atttaaattc ttatacttca aagataaata ataatcggga gaaatccgaa aaaaccgtaa
     6421 caaaacaggc ggctttttgc gaaaaacaga aaggcccggt gcacaaatgc accgggccag
     6481 gattgcagcc ggaccgaaat ccgggggcgg aagcgccccg gtcccggaaa agagaggtta
     6541 tttgccgatg gtcagcgtca ccccgcccgt acaccagaaa cccggcaagc ggattccgcc
     6601 gatgtcgcag tagcgcgtgt cggtgatgtt cgtggcgtcg acgtagaggc ggcagatgcc
     6661 cttctcccac tggagacgtc cgtcgagcag gaaatagggc ttgtagtcgc gctcttcgtt
     6721 aagggaggcg ttgcccggtt cggggtaatg cgtgtagctg ccgttgcggt cgtagaccga
     6781 gccggtcagc gcaagcgaca tccgccgcag gaaatgcacc tccacggcca atgccgcctt
     6841 gtgacgcatg aaatccatcg cgcttttggc gatgacgtcc gcgttccggt cggtcgtgat
     6901 gtagccgtac gagagcgtca cgcggcgcag gaagccttcc gaaaccgtat agccgcccgc
     6961 gagttcgatc ccgaaggtat cgagactgct cgtctgttcg gaatgccact tgctgcccat
     7021 gtcctcgcgc cagacccagt cgatgatgtc gcgcccggag cggtaatagg cttgcgccga
     7081 aaggttccag ctccgcttga ggtaatccac accaagtcgg tatgtgactg cgtgttccgg
     7141 cgtaagatcg agattgttga tctgcgccgg ggaggtgtag tagaggtccg tgaaggtcgg
     7201 caggcgcatc gactgccacg ccccggcttc gaggcgcagc ccggccgcgg gggcatagcc
     7261 cgccgaaagg ctccacaggg ccgaagtgcc gtagggcgtg aggctcacgc ccgccgaagc
     7321 cgccgcgtcg aaatgccgcc accgcttggc gtgccgcagc cacaggttgc ccgtgtggcg
     7381 cgccttggca tgggtgtaat ggccttcggg aaccgagagc ttgtcaccga gattggtgct
     7441 gtaaatgtgg ttgaaagcat agtctccgcc cacggtggta acgcccgccg cccagtcgca
     7501 gtcggcccag agcttcgctc cgacattgtc cgtgttgtgg cggttcatcg ccgtgccgcg
     7561 cgtccagtcg tagcggtcga agttcttgcg gtagctcgcg gcggccccca gcgaaaagcg
     7621 gcctgcggtt ttcagccacc gcagcgaccc cagggccgtg gcggtatgct cccactggtc
     7681 gggattgtag gccgcataga aaccgttgga gccgaaatcg cggtcctgcc acccggcctg
     7741 caagtcgaag aacccggccc gcccgccgtc gtaggtcgcc cgtacgaatg cgttgtagtt
     7801 ggagaaatcg gtattgtgcc ggtagccgtc gctgcggcgg tacgaagccg cgccgagcac
     7861 cgagaagcgt cccgcactca ccgcgcccga aagattcccg tagccatagc cgtactggcc
     7921 gcccgaggct tcgaggcgca ggtaggtggg ccgcagcggc gcggtgcgga tgttcaccgc
     7981 accggcgtag gctccgacgc ccggaacgcc gtcgatcagt tcgacggccg aaatgcagtc
     8041 gaggtcgacg ggcagcgcgt gggactgatg cccggtgcgg gcatcggtga aatcaatgcc
     8101 gttgagaagg accatggtct ggtcgaaaga gcctccccgg atgaagatgt cggcctgcgt
     8161 tcccttgcct ccgcgttcgc ggacatcgac cgaaggagca aggcgcaggg cggcttccag
     8221 agtctggaca ggcgccgggg cctgggcttt ccggtcgaaa agcggggtgt gcgactgggc
     8281 gttgcgcgcg ggagccgtct gactcccggt gacgccgact tcccgtatcc gcaatgtctt
     8341 gagaacagcg gtcgtgtcgg cagtctgcgc ggacgcacct tgcgtcgcaa gcagcaggat
     8401 cgacatcccg acagagagga ccccgatagt cacataacgg tggaggctgg caaaaaccga
     8461 ccagtttttg cgactccaac gcttgaagca ggggtactgc tttgtttgga tgttttccat
     8521 ttgtttgaaa tttgggttaa aagtgaaaaa acgtccgaac cgggtccggc tgcactggct
     8581 tccggttcgg ccccgcaaag gtaataaaaa aaaacgggct atacaggccc gtttgtgtaa
     8641 atcgcacaga agcaatcagt caacccgctg tcattcagtt gaacagcgct tcgactttct
     8701 ccaccacatc cgcctcgtcg ggttcgagcg ggaagacgtg gctcggcttg agataccaca
     8761 gctccttacc ctccttgaag tgctcctcgc cgccgcccgt gacattgagc atgacggtgg
     8821 cgtccttctc gattttaccc gcgttcacgg cattgacgag cgacgccagc gcaacgcccg
     8881 ccgccgaata gatgtcgacg ccttcgagtt cgtggaacag cttgcgggcc ttgcgcgcca
     8941 tggcgttcgt ggccacgaaa acctcgccgc cggtggcttt cagcgcatcg aaaagaccgc
     9001 ccgtgacgct gtaaggcgga cggcggttcg aaagcacctt ggcgtcgatg atctccgcgt
     9061 cgcggcgcgc cttgtcgtcg tcgtaaggca gcagcttgcg cgatgccgcc tgccaggcgt
     9121 cgtacatcgg gacgaacggg gcgttctgcg ccaccatcag cttcatcgta ttccgcccga
     9181 agcggccgtc ctccaccaga cgcatgttgg cctcccaggc ggcaatggcg cccgtgccgc
     9241 tgcccacggc ctggaaatag tagtcgggaa tgcggccgat ggtcgtcacg gccgaaagga
     9301 ccgtgcaggc catgccgtcg cgacgcgcga cgttcttggc gccgccctcg gcgtagaagc
     9361 cggggctttt cagcgcgatg tcgctcaaat ggatggcgtc gaaatagtcg ccgcccttct
     9421 cgcacgaaat gagtttcacg caggggttca gcggctggtc gaaccacagc gcaccgatat
     9481 tgtcgtaggg aaccgagagc agcagcctga tgttattgtc cgagcagacc ttggcgaagg
     9541 cccgggcggt gtttccggcc gaagccacca ccagcacgcg ccgttcgtcg gcagcggcgc
     9601 ggccgcagac cgaataggcc tcggtctcct tgaacgagca ggtcgacatc gtggccccga
     9661 tggccggata ccagccgttg aaggtgatcc agaggttttc cagcccgagg tgcgcggcga
     9721 ggcccttgct cttataggtc acgggagccg acgaaccttt gaggatacgc cgcacaggca
     9781 tccagtccga gaaacggtac aggccccagt cggcgggttt cacgtcgatc tgtttgcggg
     9841 cgtatttggt gcgcacgagc gaaggctcct tgcactgcgg gtcagcaagc atccagccgg
     9901 cgtcttcgaa ttcgcggccc gtggcgacgc attccaacgt gtagggggta ggtgtgaaat
     9961 tttccatgaa gaggtttcgt atatctgaat tcaatattgt ctatgacatg cggttccgga
    10021 agtcctcgta gccgaattcg cggatgacgt cagtgcggcc gtcgcggcgc gcgatgacga
    10081 tggacggatg gtgtacgccg ttgaacatcg tggtcttgac catcgtgtag tggatcatgt
    10141 cctcgaagac gacgcgctcc cccaccttca gctcgcggtc gaaagcccag tcgccgcagt
    10201 agtcgcccgc aaggcagctc gtgccgccca tgcgccagcg cttttcgccg tcggcgggtt
    10261 catgcgctcc gatgacggcg ggtttgtagg gcatttcgag gcagtcgggc atgtggcagg
    10321 cgaacgacac gtcaagcatc gccgtcgtca ccccgccgtt ctccacgatg tcctcgacgg
    10381 tcgaaaccag aaagcccgtg cgccacgtga aggcactgcc gggttcgagg atcagccgca
    10441 ggttcggatg gcgggacctg aacgccttca gcagggcgat caggcggtcg cagtcatacc
    10501 acgaggccgt catcaggtgg ccgccgccca tgttgagcca tttgatccgg tcgagatacg
    10561 ctccgaaatg cgtctcgacg gcctccagcg ccttttgcag atgctccggg cgcgattcgc
    10621 agaggacgtg gaaatgcagc ccctcgacac ccgccggaag tccgccgtgc gccgccagct
    10681 gttcggccgt gacgcccagc cgcgagccgg ggacgcaggg gttgtagagg tccgtctcga
    10741 cgggcgaata ctgcgggttg atccgcaggc cgcaggaaat gccgttgata agggctttct
    10801 ggccgaagcg gcggaactgc gacagcgaat tgaacgtgat atgatcgctg caattgagga
    10861 tttcgtcgat attggagtcc gtgtagaccg gggcgtaggt gtgggcggga cgcccgaact
    10921 cctcgaaaac gagacgcgcc tcggcagcgg aacttgcagt cgcaccgtcg gaatgcttcg
    10981 ccagctcggg aaaaatgctc cacatggcgc aggccttcag ggcgacgata atttcggcgc
    11041 ccgattcccg gcgcacacgg tcgacagtcg ccaggttccg gtccagcagc tcctcgtcga
    11101 ggacgtagca cggtgaaggc agtttcagaa agtcaatcat cgaattgttt ttagttggat
    11161 ttcatccttc gttttctccg ctcggcataa tccgggcaag cccggctctg ccctcgctca
    11221 acgaaaacgt ccaaaacagt tgcaaaagta gcaaaaacct cctgaaaacc acgctgcgca
    11281 ggcttggttt tcgggaaaat acgcatttat acttatcgct tgcgaaaccc ggtccggaaa
    11341 taagcatcgg agccggtcgc cggcaggggc atttcgggaa aagcggttct gcggaaaacg
    11401 atacgacagt tttgattttg gaggagcgga aaatccctct gcggttttcg atcggtgcgg
    11461 tgcatctgtc gtgcatcgtg aaaaatcccc ggatgggacg tacttcggca ctatccatcc
    11521 ggggattttg agggatgtgc ggcatctgcg ccgcaatctt caaaaaccta cacttcgaga
    11581 ttcacatcga acagctcgtg ccacggcagg ccctgctcgc ccagctcggc gaggaacgga
    11641 tcgggatcga actcctcgac gttgaacacg ccggcgccgc gccagaggcc cttggcccac
    11701 atcgaagcgc ccaaagccgc cggaacgccc gtggtgaacg acacggcctg cgtgccggtc
    11761 tccttgaaag cttgttcgtg gtcgcagttg ttatagatat agtaggtgcg ctccttgccg
    11821 tccttcaggc ccttgatgcg gcagccgatc gaggtctggc cgtgatagtt ggcgcccagc
    11881 gacttgggat cgggaagaac cgccttgagg aactggatcg ggacgatctc gaccccgttg
    11941 tagatgatcg ggtcgatacg cgccatgccg atgttctgga tcacgcgcag gtgcgtcagg
    12001 tactcctgac cgaaggtcat ccagaagcgc gcacgccgga tcgtgggata gttcttcacg
    12061 agcgactcca gctcctcgtg gtagatgacg tacgactcgc gctcgccgat gcccggataa
    12121 ttgagcggct tgtggatctc gtgcggctcg gtcaccaccc actctccgtt ctcgtaataa
    12181 cgccctttct gggtcacctc gcggatgttg atctcggggt tgaagttcgt ggcgaaagcc
    12241 atgccgtggt tgccggcgtt gcagtcgacg atgtcgaggt agtggatttc atcgaaatgg
    12301 tgcttggcgg cataggccgt gaagatggcc gtcacgcccg ggtcgaaacc acagccgagg
    12361 atcgccgtga gtcccgcggc cttgaagcgg tcctgatagg cccactgcca cgagtattcg
    12421 aaatgcgcct cgtccttcgg ctcgtagttg gccgtgtcga ggtagttgca gccgcattcg
    12481 aggcaggcgt ccatgatcgt gagatcctgg tacggaagcg ccacgttgac cacgatgtcg
    12541 ggtttgaacg cgcggaacag ttcgcacagc tgcggcacgc tgtcggcgtc gacctcggcg
    12601 gtcttcacgc ggttgccgcc gatggcggcc gcaacggcgt cgcatttgga tttggtacgg
    12661 ctggccagca tcacgtccgt gaagacggga ttggccgcga ttttctgcgt caccaccgtt
    12721 ccgacgccgc cggctccgat tatcagcgct ttacacatag aattattcgg ttttaaaagt
    12781 tagatttcat cttaacgcct acaaaaatat ccttttattt cggcaaaaca aaatccgcac
    12841 gccaaatttc acgatcccgg ccggccgaaa ccgccggaag atgcccggac gcctatcgcc
    12901 tgcaggcggc aggcggcagc cggaaaggca aaaaacacac ttttgcgcaa aatttgcagg
    12961 ccgggtattg gattttaaaa ataaatccgt acatttgcac caccaaaacg gaaacgattc
    13021 ccattttggc acacggagat tccgtagctc agctggtaga gcacaacact tttaatgttg
    13081 gggtcctggg ttcgagcccc agcgggatca ccagagaaag gaaggtcgag gccttccttt
    13141 tttcgttttc gggaaggaga gaccggtttt atccggccgg ttcccgcgca tcggccgcgt
    13201 caggtcaacg ctctccggaa agcaggtcga cgtattccca ctcccggccg ccggcacgtt
    13261 tgagtttcgg aggctcgctg caacactggc tgatcgccga gcggctgacg ccgtatttgg
    13321 cggcggcttc ccgaagcgtg tcgaacacct caccggtggt gatgcacctt accttccggc
    13381 ttcgtcgtcg cagcatcgcc caaacggagc atttccggca gccggaagag cgggatttcg
    13441 cgatgaggcc atacgcctgc gccgaccata catggccgca ggccctgcac tcgaatgtca
    13501 tgcgggtctg gctgttgaca tactcggtca gagggacgat ctccggatgc aacaggttca
    13561 atctttcgac gaaccgttca tgcgtgagtt tcaacctgcc ggcacagctg gcgcatcccg
    13621 aaccccggcg cagggtcgtg ggcgcaacgg accactcgtg attgcagacc ttgcaccgca
    13681 ccctgatttt atcagaggcc ctcgtgtatt cgccgataac ctcgatttta tcattgatcc
    13741 cggccagctc cgcccggaat tcttcggtgg tcatccgccg cgaatccagt tcggccctcc
    13801 tccggatcgt ctcccattcg cccgcggcga ggttcgaatc cagcccgaac gccccgagga
    13861 gggttttcgt caccgcaacc agcttgtcca tattccggcg ggaggcaagg tcgcagggag
    13921 tcaccaggca gtcgtcgaaa ggaacggccg tttcatcata atggtcatat acggttatca
    13981 gccggatgcc tttcctttcg cacagcaggc gcttttcccg atccctctcc accagattcc
    14041 ggtgccagta ccacgaaccg ggttccacgg ccgccctcaa ggcgggaatg cagacgtcca
    14101 gttcgacacc agccgcagtc ttgtcccgcg acaggacttc cgattcgccg agcatgcgga
    14161 caaaggcgtg gcggataaac tgttccggaa aggaagtgca tgccctgtgg cagttcggac
    14221 agccgccgcc gtgcagaaca tcgcccggct ttacttcgta ctcgtatttg caggcgttgc
    14281 agcggagagg gatcggcgtc gtatagtcct taattccgca acactataat ttaactttat
    14341 ttataagttc ctgagcaaca aaaagttgct caggattttg ccatgtcaga tttttcactt
    14401 atctt
//
