LOCUS       c00023_gnlPro..        16526 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JEPOKCAC_23.
ACCESSION   c00023_gnlPro..
VERSION     c00023_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 08:40:05
            Original ID  :: gnl|Prokka|JEPOKCAC_23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16526
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16526
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3599:6526]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3600..6526
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..16526
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16526
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             256..1692
                     /locus_tag="ctg23_1"
                     /transl_table=11
                     /translation="MATTAGAKKGLWSTIRRIAASDRISGLIMLGFALTGLVLANLPAT
                     AHAFETVAETHLFIPYTNLDLPIGHWAQDGLLTIFFLTVGLELKQELTTGSLANPKAAA
                     VPMLCAVGGMIAPPILFLAVTALFSQIGPGEPGTLILTTTGSSIPFSEMSHGWAVPTAT
                     DIAFSLAVLALFAKALPGSIRAFLMTLATVDDLLAIILIAVFFSSINAWYWFIGIAVCA
                     AIWAYLVRLKKVPWIAVGIVGILAWIMMFEAGVHPTLAGVLVGLLTPSREMHGELSPRA
                     ERYANKLQPFSALLALPIFALFATGVHFESMSPLLLVSPLVIALIVALVVGKPLGIITT
                     AWLATHVGGLKMAKGLRVRDMIPAAVACGIGFTVSFLIASLAYKNAELSAEARFGVLVA
                     SLIAAAISGVLLSRQSKRFEKAAAAQAAAAEALADAEAGESIDGNGTGQPSRTTKPATP
                     TEHPGTLADGTASVEIDFRH"
     CDS             1854..2795
                     /locus_tag="ctg23_2"
                     /transl_table=11
                     /translation="MAKKQKKSKKNGGKKAAEAKNPAEAASQSAVVDDMEPLEATAAND
                     TATLEAETATEAAATLVNPVDLEEASPLGDTYHRGPVILRGQMIPPDNTTANLLKPDQD
                     TDWLHMDPWRVLRIQSEFVDGFGALAELGPAVSIFGSARTQRTESIYKAARRMGSQIAK
                     RNIAVITGGGPGIMEAANRGAALAGGKSVGLGIELPHEQGLNQWVNLGMSFRYFFVRKT
                     MFVKYSSGVIVCPGGFGTLDEMFELLTLVQTHKVANIPVVLYGKEYWQGLFDWLNGPVA
                     EHGMISTIDPKLVTVTDDADEAVDVVVSAIVR"
     CDS             complement(2841..3506)
                     /locus_tag="ctg23_3"
                     /transl_table=11
                     /translation="MDRTQYTNLAKAWEFTEEHARERESDALTDARTAADESGQLQGSA
                     AQARLLGMLVRITGAASVIAVGTGSLVETLQLAHALDSKGLLTAVDSTAQGIALIRKAF
                     AELQDETDTTLRAVNAPASVFLPRLNANDYDLIVVAGDAENYAATFAQASRLLRAHGVI
                     VFTDVLALEDGQGGVINPADRSDKAIAMRELLATVEDDEGFESTLTPDGTGLLIAYKK"
     CDS             complement(3600..4565)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 146.2; E-value: 1.1e-45)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_4"
                     /sec_met_domain="Fer2_3 (E-value: 3.7e-45, bitscore: 146.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 1e-11, bitscore: 38.9,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEASNTTVTLQVHRFTPRPERAERARGGSPFAKKNSPFGGGSDS
                     AARRRPRGKQWVQEYTIPARPSDTVLDCLLTIKRTVDPTLAFRYSCGHGMCGSDAVAIN
                     GTPTLLCTATIRDWAKQPGALPEVDDEGFRHTGTEAEESDDSAENVANAAADQDSAANG
                     SLGVIELASLPGFPPQRDLIADIDPMLNQIRKLTPYLRADGVLVTTAEGKVDVFEYLQN
                     PEQLAKYELLSNCIACGVCEGACPVYAGGDAFIGPAALIWASRFVNDSRDTKAMERMDA
                     IDTADGVAACQSVRACSRHCPRGIDVGEEMWQIVAKVRER"
     CDS             complement(4661..6526)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 335.7; E-value:
                     1.5e-102)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 5e-102, bitscore:
                     335.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 5e-29, bitscore:
                     94.6, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPKRLEDMYDAVIVGAGAAGLSAALGLLRSPEITELREQGVDPK
                     ILVVSKLQPLRSHTGSAEGGIAASLGNVESDDWRWHYYDTIKGGDWLVDQDAAKLLAEY
                     APQTVINLERQGVAFSRTEDGHIAQRRFGGHTREFGGAPVKRAAYAADRIGHQILHALW
                     QQCVAAGVEFAEEWYVTDLVLADDGKQAAGIVAFDTHSGKIQAIHARNVLLATGGAGRL
                     FHTTSNSWDLTGDGMALTLAAGLQLEDIEFVQFHPTGLAHTGILLSEAARAEGGILRNA
                     DGEAFMERYAPEHRDLAARDVVSRSIMAEIDAGRGVADPKDPDGPKDCVWLDMTGIDPE
                     RMKEVLPQVVETIEQYANLDPVKDLVPIKPTAHYTMGGIPITTNGEVYRWAYGAVQVVD
                     GLFAAGECSCVSVHGANRLGGNSLLDACLFGTRAGQTMAARIAENPVDSPMAEDSADDM
                     LTDAADQAADSRKAELDELLAGPMGDSDDGTTTANPYQLMAQLGSVMEQALAVRCTAQA
                     IDTALTQINNDITPVADTLRAHDKTAAFNQEVTAIWEVRHLIELAEAMLHASESRQESR
                     GSMQRLDFPERDDEHFLAHSMVADDGPVSFKPVHITDYPPKKREY"
     CDS             complement(6583..8283)
                     /locus_tag="ctg23_6"
                     /transl_table=11
                     /translation="MSNATDIRQSGGTAGSVDHTDTGLAVSRTIPMPPTDTLYRAALTF
                     CLDGADVMMYATLKGAESAESLWHALAQSHPSQPSEICGPALSRIDRMFVDGLTRWGRK
                     ASANAMRSFRNALSGWHNRMMDLPSQDIIQLADWFTMDGTQWIIGPGHPCWPSQLADLS
                     IRSDWAPPLCLWIKGDPRALTSCAKPVGIVGSRDVTEYGRYVAHTVAEQAAVAGHLVVS
                     GGAMGTDAAAHWGALNALHGRMPANVGRTVAVFAGGLNHIGPMRNRTLFERIEAQGGAL
                     ISELCPGTIPEARRFLLRNRIIAAMSSTLIVTQARLRSGALNTAGWACELLREVYAVPG
                     DINQPCNAGCNKMIGDHRAMILCAATSTEDICHERHKPVMGVCPGISKSIGQDSSENEE
                     AMEVPATTPLSPASSESSASQESSQDPGHSKRLKTKHTQPTLVQSKDGPASATAETGAN
                     KSKGEELPSSHQMPDLRVKPKPDPEKEAQQRIIIAKLPEMERTLVALIRECRKRHLIVT
                     PDALLRVARETVPDEIPNIGTILELLGALELRGVIERDAGILKLSSRVG"
     CDS             complement(8280..9815)
                     /locus_tag="ctg23_7"
                     /transl_table=11
                     /translation="MAIGSTLSVGLIGLKAFIVQVQAFISPGLPYFSIIGLPDASLSEA
                     RERVKSACQATGFGWPQTRVTVNMSPAAMPKRGSSHDLAIAASVLCAAGAIGHDCLEDT
                     IVLGEVNLDGSVLPIHGLLPIMLHAEERGVRKMIVPHRNLDEASMVDGLDVVGVRHVGE
                     LIELMGGDATYTITDTPVADETTMDQSPTSHPNDCGDMNEVLGQEHAKWALQVAAAGGH
                     NLIMTGPPGSGKTMLASRMPGIMCPLNEAEQLEVASIRSLCGILPQYGITDMPPFEAPH
                     HTASTAALVGGGSGIAVPGAITRAHRGILFLDEAPEFSARALQTLREPLESGYVALSRS
                     KGSTYYPASFQLIMAANPCPCGYYYGTGERCACREKDRIRYFSRLSGPILDRVDIQMAV
                     PPVSRIAVQSEPIGESSAGIQARVIRARQVAKDRFRQYGWVCNAQASGKWLHANTSLKA
                     MELVNRALSNHQLTLRGADRAMRLSWTLADLAGRVSPTERDVHQGIEMRTRMT"
     CDS             complement(9871..10374)
                     /locus_tag="ctg23_8"
                     /transl_table=11
                     /translation="MNALPPTQPTTKSGIDAGLAFHQPMLASPDPQATLPSERIAATMG
                     DRNLTPKQFGALGEQYAAAWLEEHGWTTLSRNWHTRYGELDIVMLNPEYTVVFVEVKSR
                     RSMHYGYPQEAITPVKQHNLRKAACDWLLDRRNRVPHTAVRFDVVTIVLRVGRPLVHHI
                     ENAF"
     CDS             complement(10610..11482)
                     /locus_tag="ctg23_9"
                     /transl_table=11
                     /translation="MTDVTLYDRDPSYIPRVAAVHDMCGYGKCSLTAAIPILSAAGCDV
                     CPVPTALFSAHTRYAVFTFHDTTDILSGYLDAWQKEDVELDGVYSGFLGSPDQVAIIQR
                     LYREYPNALRLVDPVMGDAGEMYPTYTPELCEAMGALADGADVLMPNLTEASILTKRDY
                     PGQNIDEATVNELLGALLKLGAKNVVLKGIDHGDGKIVNYVASASTGVAGKIELAHEKL
                     PYMIHGTGDAFASALCGAVMAGRGLAKSAEIAGEFVRHAMVSTRDQPHFEDRGVSFELN
                     LGELTDLVK"
     CDS             11958..13274
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cys_Met_Meta_PP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_10"
                     /sec_met_domain="Cys_Met_Meta_PP (E-value: 8.1e-136,
                     bitscore: 446.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAENSKKYRFETLQLHVGQEQADPATDSRAVPIYATTSYVFHNFD
                     HAEARFGLADPGNIYGRLTNTTQGVFEDRIAALEGGTAGLAVASGAAAVEYAVRNITQS
                     GDHIVAAKNIYGGTFNLLRHTLPRDGITTTFVSAENPQEFEDAIQENTKLVYFETFGNP
                     NADLPDFEAISEIAHKHNLPVIVDNTFATPYLFRPLEHGADVVVESATKFIGGHGTTLG
                     GVIVEGGNFDWNAVPGKFPTLTEPDPSYHGLNFYEALGGTAFVTRIRAILLRDTGATLS
                     PFAAFLLLQGTETLSLRVERHVQNALKVVEYLQTVPEVESVSHPSIPGRPDHDLYEKYF
                     PNGAGSIFTFDIKGGKDAARVFIDNLHLFSLLANVADAKSLVIHPASTTHSQETLEELE
                     DQGIHQGTIRLSIGTENIEDILDDLKGGFEALRASGLAK"
     CDS             13753..14667
                     /locus_tag="ctg23_11"
                     /transl_table=11
                     /translation="MNVQNPAASRGIAIQAVDLVKNYGTGSNMVHALRGVNVSFERGEF
                     TAIMGPSGSGKSTLMHTLAGLDSATSGHILFGGADLTRMDDKQLTLLRRHKIGFIFQSF
                     NLLPMFTAEQNILMPLTLAGDKPDRAWFDLLVETLGLQQRLNHRPNELSGGQQQRVAIA
                     RALITKPKLVFADEPTGNLDSVSSAEVLGFLKRSVNELGQTIVMVTHDAVAASYADRAI
                     VFADGQIVADEANPTAETMNELLMAERERATRTAVTGTRADTLARLAGVKDVPNLPITD
                     APLPPAGRTGTMRHARVAAQHAC"
ORIGIN
        1 atgcgccagt agcccagcgg attagagcag ctgactacgg atcagcaggt cgcaggttcg
       61 aatcctgtct ggcgcacagt aagcctcgaa agcgaaatgc ttccgaggct tttccaattg
      121 cattggcccg tttgagtcgg tcacacaggg ttgggttgag gttacccctt cacggctcag
      181 cccggagcgg aacgtcctga gatattccgt actattacat acggttcatc caagagagta
      241 cagcaaggag acgcgatggc tacgaccgct ggcgcgaaga agggactttg gtccaccatc
      301 aggcgaatcg ccgcctcaga ccgtatttcc ggactcatca tgctcggctt cgcgctcacc
      361 ggcctggtgc tcgcgaacct gcccgccacc gcgcatgcgt tcgagaccgt agcggaaacg
      421 catctgttca tcccctacac caatctcgac ctgccgattg gccattgggc ccaggatggt
      481 ctgcttacca tcttcttcct gaccgtgggc ctcgaactga agcaggaact caccaccggc
      541 tcgctcgcca atccgaaagc ggccgccgtg ccgatgctgt gcgcggtggg cggcatgatc
      601 gccccgccca tcctgttcct ggccgtcacg gcattgttct ctcagatcgg gcctggtgaa
      661 cccggcacgc tgattctgac caccaccggc agcagcatcc cgttctcgga gatgtcgcac
      721 ggctgggcag tacccaccgc cacggatatc gcgttctcgc tggccgtgct cgccctgttc
      781 gccaaggccc tgcccggttc aatccgcgcg ttcctgatga cgcttgccac cgtcgacgac
      841 ctgctggcca ttattctgat cgccgtattc ttctcctcga tcaacgcctg gtattggttc
      901 atcggcatcg ccgtatgcgc cgccatctgg gcatacctcg tacgactgaa aaaagtgccg
      961 tggatcgcgg tcggcatcgt cggtatcctc gcttggatca tgatgttcga ggcaggcgtg
     1021 caccccacac tggccggcgt gctggtcggc ctgctgaccc cctcccgtga aatgcacggc
     1081 gaactctcac cgcgtgccga acgctatgcc aacaagcttc agccattctc cgcactgctg
     1141 gccctgccca tcttcgccct gttcgccacc ggcgtgcact tcgagtcgat gagcccgcta
     1201 ttgttggtct cgccgctggt cattgcactg attgtggctt tggtggtcgg caaacctctg
     1261 ggtatcatca ccaccgcatg gctggccacg catgtgggcg ggctcaagat ggccaagggg
     1321 ctgcgcgtac gtgacatgat tcccgctgcc gtcgcctgcg gcattggttt tactgtgtcc
     1381 ttccttatcg cttcgctggc gtacaagaat gcggaacttt ccgctgaggc gcgcttcggc
     1441 gtgctggtgg cctccctgat cgccgccgcg atttccggtg tgctgctgag ccgtcagtcc
     1501 aagagattcg agaaggccgc agccgcgcag gctgccgccg ccgaggcgtt ggccgatgcc
     1561 gaagccggcg aatcgattga tggcaatggc accgggcagc caagccgcac cacaaagccc
     1621 gccacgccca cggaacaccc cggcaccctc gccgacggca ccgccagtgt ggagattgac
     1681 ttccgccact gatggctaag acggtcccta ctccgttgtt ggccttgttt cgtgaaaacc
     1741 gtacgctgag acgcgctcag agtacgttct tcacgaaatt tcgcggaaaa cgtacgcaga
     1801 gcttcaggcg ctagaatgcg aagagtcgat agcaccgtac aggaggacat tggatggcaa
     1861 agaagcagaa gaaatccaag aagaacggcg gcaaaaaggc cgctgaagca aagaatccag
     1921 ccgaggccgc gtcccagtcc gcagtcgtgg acgatatgga accattggaa gccacagctg
     1981 cgaatgatac ggcaacgttg gaggctgaga cggcaactga ggctgcggcc acactggtga
     2041 acccggtcga cttggaggag gcttcgccgc tgggcgacac ctatcatcgc ggcccggtga
     2101 ttctacgcgg ccagatgatt cccccggaca acaccaccgc caacctgctg aaacccgacc
     2161 aggacaccga ctggctgcac atggacccat ggcgtgtgct gcgcatccaa tcggaattcg
     2221 tggacggctt cggggcgctc gccgagctcg gacctgcagt ctcaattttc ggctccgcac
     2281 gcacccagcg cactgaatcg atctacaagg cggcacggcg catgggtagc cagatagcca
     2341 agcgcaacat cgccgtcatc accggcggtg gtcccggcat catggaagcc gcgaataggg
     2401 gagcggcact ggccggcggc aaatccgtgg gactcggcat cgaattgccg cacgagcagg
     2461 ggttgaacca gtgggtgaac ctcggcatga gcttccggta cttctttgtg cggaagacca
     2521 tgttcgtcaa gtattcctcg ggcgtgatcg tgtgcccggg cggcttcggc acactggatg
     2581 agatgttcga gctgctgacc ttggtccaga cccacaaggt ggcgaatatt ccggtggtgc
     2641 tctacggcaa ggaatactgg caggggctct ttgactggct caacggtccg gtggccgagc
     2701 acggcatgat ctcgacgatc gacccgaaac tggtcaccgt aaccgacgac gccgacgaag
     2761 ccgtggacgt ggtcgtcagc gcaatcgtga gataagcgag atagagtggc tcccctctcc
     2821 gaggggagcc aaggacagag ttactttttg taggcgatga gcaggccggt gccgtcaggg
     2881 gtgagcgtgg actcgaaacc ttcgtcatct tcgacggtgg cgagcaattc acgcatggcg
     2941 atggccttgt cgctgcggtc ggccggattg atcacgccgc cctgaccgtc ctccaacgcc
     3001 agcacatcgg tgaacacgat cacgccgtgc gcgcgcagca gacgggaggc ctgggcgaac
     3061 gtggcggcat agttctcggc gtcgcccgcc accacgatca gatcgtaatc attggcgttg
     3121 aggcgcggca gaaacacgct ggccggagca ttcaccgcac gcaacgtggt gtcggtctca
     3181 tcctgcagct cggcgaacgc cttgcgaatc agcgcgatgc cctgagcggt ggaatcgacc
     3241 gcagtcagca ggcccttgct atccagcgca tgggcgagct gcaaggtctc caccagcgag
     3301 ccggtgccca cggcgatgac cgaagcggcg ccggtgatgc gcaccagcat gcccagcaga
     3361 cgggcctgcg ccgccgaacc ctgcaactgg ccggactcgt cggcggccgt acgggcgtcg
     3421 gtcaacgcat cggattcacg ttcgcgcgcg tgttcctcgg tgaattccca tgccttggcg
     3481 aggttggtgt actgcgttct gtccataatt cgttccttca tgtcttctct cgtgcgggca
     3541 cccggcggat gcatcgacgc atgtgcttag acgatcgccg cagccagccg cggcgcggct
     3601 tagcgctcgc ggaccttggc cacgatctgc cacatctcct cgcccacatc gatgccgcgc
     3661 gggcagtggc gggagcaggc gcgcacggac tggcaggcgg ccacgccgtc ggcggtgtcg
     3721 atggcgtcca tacgctccat ggccttggtg tcgcgcgaat cgttgacgaa acgggaggcc
     3781 caaatcagcg cggccgggcc gatgaaggcg tcgccgccgg cgtacaccgg gcaggcgcct
     3841 tcgcacacgc cgcaggcgat gcagttgctc agcagctcgt atttggcgag ttgttcgggg
     3901 ttctgcaggt attcgaacac gtccaccttg ccttcggcgg tggtgacgag cacgccgtcc
     3961 gcccgaagat atggggtgag cttcctgatc tggttgagca tagggtcgat gtcggcgatg
     4021 aggtcgcgct gcggcgggaa gccgggcagg gatgccagtt cgatgactcc cagtgaaccg
     4081 tttgcggccg agtcctggtc ggccgccgcg ttcgcgacgt tttccgcgga atcgtcggat
     4141 tcctcagcct cggtgccggt gtgtcggaac ccttcgtcat cgacttcagg cagggcgccg
     4201 ggctgcttgg cccaatcgcg gatggtggcc gtgcatagca gggtgggggt gccgttgatt
     4261 gccacggcgt ccgaaccgca catgccatga ccgcacgaat aacggaaagc cagcgtcggg
     4321 tcgacggtgc gtttgatggt cagcagacaa tccaacacag tatccgaagg gcgcgcggga
     4381 atcgtgtatt cctgcaccca ctgcttgccg cgcggacgac ggcgtgccgc cgaatccgag
     4441 ccgccgccga acggggagtt tttcttggcg aacgggctgc cgccgcgtgc acgttcggca
     4501 cgctcgggtc gcggcgtgaa acgatgcact tgcagggtaa ccgtcgtgtt gctcgcctca
     4561 gccatgttct gcctccatga aacagtggga tgtcaagtcc agtattagcc aacctattgt
     4621 gccacaagcc ctaggcggct tgggtattac caccagcgga tcagtactcg cgcttcttgg
     4681 gcggatagtc ggtgatgtgc accggcttga aacttaccgg accatcatcg gcgaccatcg
     4741 agtgagcaag gaaatgctca tcgtcgcgtt cggggaaatc aaggcgttgc atggatccgc
     4801 gagattcctg acgggattcg gaagcgtgca gcatggcctc ggccagttcg atcagatgac
     4861 ggacttccca gatggcggtg acctcctgat tgaaagcggc ggtcttgtca tgggcccgca
     4921 aggtatcggc aaccggcgtg atgtcgttgt tgatctgagt caacgccgta tcgatggcct
     4981 gagcggtgca acgtacggcc agagcctgct ccatcactga tccgagttgg gccatgagct
     5041 gataaggatt ggcagtggtc gtcccatcgt ctgaatcacc cattggtccg gcgagcagtt
     5101 cgtcaagctc tgccttgcgg gaatcggcag cctgatcggc ggcatcggtc agcatgtcat
     5161 cggctgaatc ttcggccata ggggagtcaa ccgggttctc ggcgatgcgt gcggccatcg
     5221 tctgaccagc gcgtgtgccg aacaggcagg cgtcgagcag agaattgccg cccagacgat
     5281 tcgcgccatg tacggagaca caagagcatt cgccagcggc gaacagtcca tcgactacct
     5341 gcacggcacc gtaggcccaa cggtacacct cgccattggt ggtaatgggg atgccgccca
     5401 tcgtgtaatg cgcagtgggc ttgataggca ccaggtcctt gaccggatcg aggttcgcgt
     5461 actgctcgat ggtttcgact acctgcggca gcacttcctt catacgttcg gggtcgatgc
     5521 cggtcatatc cagccagacg cagtccttcg gaccatccgg gtccttcgga tcggcgacgc
     5581 cgcggccggc gtcgatctcc gccatgatgg agcgggagac cacgtcgcgc gcggccagat
     5641 ccctatgctc cggggcgtag cgttccatga acgcctcgcc gtcggcgttc ctcaggatgc
     5701 cgccttcggc gcgggccgcc tcggacagca ggatgccggt gtgcgcgagc ccggtgggat
     5761 ggaactgcac gaattcgatg tcctccagct gcagaccggc ggccaaggtc aaggccatgc
     5821 cgtcgccggt cagatcccag gaattcgacg tggtgtggaa cagtcggccc gcgccaccgg
     5881 tggcaagcag cacgttgcgc gcgtggatgg cctgaatctt gcccgaatgc gtgtcaaagg
     5941 ccacgatgcc ggccgcctgc ttgccgtcgt cggcgagcac caggtcggtc acataccatt
     6001 cctcggcgaa ctcgacgcct gccgccacgc actgctgcca caaggcgtgc agaatctggt
     6061 ggccgatgcg gtcggccgca taggcggcgc gcttgaccgg ggcaccgccg aactcgcgcg
     6121 tgtggccgcc gaaccggcgc tgggcgatat gcccgtcctc ggtacgggag aaggccactc
     6181 cctgacgctc caggttgatc acggtctgcg gcgcgtattc ggcgagcagt ttggctgcgt
     6241 cctggtcgac gagccagtcg ccgcccttga tggtgtcgta gtaatgccag cgccagtcat
     6301 cggattccac attgcccagg ctcgcggcga tgccgccctc ggccgaaccg gtgtgcgaac
     6361 gcagcggctg cagtttggag accacgagga tcttcgggtc cacgccttgt tccctgagct
     6421 cggtgatttc gggggagcgc agcagtccca acgccgccga caggccggcc gctccggcgc
     6481 cgacgatcac cgcatcatac atatcttcca aacgtttcgg actcatgggt tcgattctcg
     6541 cacacccgcc gaacagcctt cgagccgtgt catggaagcc gattagccga cacggctgct
     6601 cagcttgagt atgccggcat cccgctcgat cactcccctc agctccaagg cgccgagtag
     6661 ctcaagtatg gtgccgatat tgggaatctc gtcgggtacc gtctctcgcg ccacacgcaa
     6721 tagtgcgtcc ggagtgacga tgagatgtcg tttacggcat tcacgaatca atgccactaa
     6781 tgtgcgctcc atttccggca gcttggcgat aatgatacgt tgttgggctt ccttctcggg
     6841 atcgggcttc ggcttgacac gaagatccgg catctgatgc gacgagggca gctcttcacc
     6901 cttgctcttg ttggcaccgg tctcggcggt tgcgctcgcc ggcccatcct tggattgaac
     6961 gagtgtaggc tgagtatgct tggtcttaag acgtttcgaa tggcctggat cttgtgacga
     7021 ctcctgtgac gccgatgatt ccgaggatgc tggcgataac ggagtcgttg ccggcacttc
     7081 catggcctcc tcgttttcgg acgagtcctg acctatggat ttcgatatgc ctgggcatac
     7141 tcccataacg ggtttgtgcc gttcatggca tatatcctcg gtggatgtgg cggcacacag
     7201 aatcatcgct cggtggtcgc cgatcatctt attgcacccg gcgttgcaag gctgattgat
     7261 gtcaccggga actgcataca cttcgcgcag caattcacat gcccatcccg cggtgttgag
     7321 cgctccggaa cgcaaccggg cttgcgtcac aatcaatgtg gaagacatgg ccgcgataat
     7381 gcggttgcgg agtagaaaac gacgggcttc gggaatcgtc cctggacaca gttcactgat
     7441 cagtgcacca ccctgtgcct cgatacgttc gaacagcgtg cggttacgca tcggtccgat
     7501 atggttgagc ccgccggcga atacggcaac ggttctgccc acattggcgg gcattctgcc
     7561 gtgcagcgca ttcaacgctc cccaatgtgc cgccgcatcc gttcccatcg cgcctccgga
     7621 cacgaccaga tgcccggcaa cggctgcctg ttcggctacg gtgtgcgcca cataccggcc
     7681 atattcggtc acgtcccgtg aaccgacgat gccgaccggt ttggcgcaac tggtcaatgc
     7741 gcgtggatcg cctttgatcc acagacacag cggtggcgcc caatcggagc gaatggacag
     7801 gtcggccaac tgcgagggcc aacatggatg gccagggccg ataatccatt gcgtgccatc
     7861 catagtgaac cagtcggcca gttggatgat gtcttgcgag ggcaggtcca tcatgcggtt
     7921 atgccagccg gacagtgcat tgcggaagga gcgcatcgcg ttcgccgacg ccttgcggcc
     7981 ccatcgagtg aggccgtcca cgaacatgcg gtcaatacgt gacagcgccg ggccgcagat
     8041 ttcagatggc tggcttggat gggattgcgc caacgcgtgc cagagggatt cggcgctttc
     8101 cgcgcccttg agcgtggcgt acatcatcac atccgcccca tcaagacaga acgtgagcgc
     8161 ggcgcggtat aacgtatccg tgggaggcat gggaatggtg cgcgaaacag cgaggcccgt
     8221 atcggtgtga tccacactgc ctgcggtgcc gccagattgt cggatatcag tagcgttact
     8281 catgtcatcc tcgttctcat ttcgatgccc tgatggacgt cccgctcggt gggggacacg
     8341 cggccggcca gatcggcgag cgtccaagac agacgcatgg cgcgatcggc cccgcgcaat
     8401 gtgagttgat gattggacag ggcccgattg accaattcca tcgctttcag cgacgtattg
     8461 gcgtgcagcc attttcccga agcttgcgcg ttgcacaccc atccgtactg tctgaaccgg
     8521 tccttggcca cttgacgggc gcgaatcaca cgagcttgta ttccggcact ggactcgccg
     8581 attggctcgc tttgcacggc aatgcgcgag accggtggca ccgccatctg aatatccaca
     8641 cgatccaata tcggtccgga caatcgcgag aaataacgta tacggtcttt ttcccggcaa
     8701 gcgcaacgtt cgccggtgcc gtaatagtat ccgcacgggc aggggttggc cgccatgatg
     8761 agttggaatg aggccgggta ataggtgctg ccttttgaac gggaaagcgc cacatacccg
     8821 gattccaatg gttcgcgcaa cgtctgcagg gcgcgtgcgc tgaattccgg tgcctcgtcc
     8881 aggaacagaa tgcctcgatg cgcgcgcgtg atcgcgccgg gaacggcgat gccgctgcca
     8941 ccacccacca aggccgccgt gctggcggtg tggtgcggtg cctcgaacgg cggcatgtcg
     9001 gtgatgccgt actgaggcag tatgccgcac agcgaccgaa tcgacgccac ctccagttgt
     9061 tccgcctcgt tcaacgggca catgatgccg ggcatacgtg aggccagcat ggttttgccg
     9121 ctgcctggcg ggccggtcat gatgagatta tgtccgcctg ccgccgccac ttgcagcgcc
     9181 catttggcat gttcctgacc cagaacctcg ttcatatcgc cacaatcgtt gggatggctt
     9241 gtgggcgatt gatccatggt ggtctcgtcg gcaaccggtg tatcagtaat cgtataggtg
     9301 gcatcgccgc ccatcagttc gatgagctca cccacatgcc tcacgcccac tacatccagt
     9361 ccatccacca tcgaagcctc gtcaagattg cgatggggaa caatcatttt gcgcacgcca
     9421 cgttcctcgg catgcagcat gatcgggagc agcccatgaa tcggcagcac cgagccgtca
     9481 agattcactt cgccgagcac aatggtatct tccaagcaat catgccctat ggcacccgcc
     9541 gcgcatagga cgctggccgc gatggccaga tcatgcgacg aaccacgttt gggcatggcc
     9601 gcagggctca tgttcacggt cacgcgggtt tgcggccaac cgaatccagt ggcttgacac
     9661 gccgatttca cgcgctcgcg ggcttcggac aacgatgcat ccggcaatcc gatgatgctg
     9721 aagtatggca agccagggct gatgaaagcc tgcacttgga cgatgaaggc cttaaggccg
     9781 atcagtccga ctgagagagt gctgccgata gccatgtcta ctcctttcgc aatgtgtttc
     9841 gcaacgtggc tgtttttttg ggggacgaat tcagaaggcg ttttcgatgt gatgcacgag
     9901 cggtctgccc acccgaagca cgatggtgac gacatcgaaa cggactgccg tatgcggcac
     9961 acgattacgc cggtcaagca gccaatcgca ggcggctttc ctgagattgt gctgtttcac
    10021 cggcgtgatg gcctcttgcg gatatccgta atgcatggac cggcgtgatt tcacttcgac
    10081 gaacaccacc gtgtactcgg gattgagcat cacgatgtcc aattcgccgt aacgggtatg
    10141 ccaattgcgg ctcaaggtcg tccaaccgtg ttcctccagc cacgcggcgg catactgctc
    10201 gccgagcgca ccgaactgtt tgggcgtcag attgcggtcg cccatcgtgg ccgcaatccg
    10261 ttccgaaggc agcgttgcct gcggatcagg tgaagccagc atgggctggt gaaaggcaag
    10321 accggcgtcg atgccggact tcgtcgtcgg ctgggtaggt ggtaaagcgt tcatgattcc
    10381 actgtgcggg ttacttatgt aagagcacaa gcgcaaccgg caaatgtgga tactatgacg
    10441 cggtttggcg tgttgtggat aacgtgtgga tgaaaacccg gttatccacc attagttcag
    10501 aaggtttacc aaggctcccc agccgactta cctgtgatga caaacaaccc gccgagttgt
    10561 tcgctgaata cgtcagaccc agtgagcgga gaggggagcc aaggtgcggt cacttcacca
    10621 aatcggtgag ttcgccaagg ttcagttcga agctgacgcc acgatcctcg aaatgcggct
    10681 ggtcacgggt gctgaccatg gcgtgtcgca cgaactcgcc ggcgatttcg gccgacttgg
    10741 ccaagccgcg gccggccatc accgcgccac acagggcaga tgcgaaggcg tcacccgtgc
    10801 catgaatcat gtatggcagc ttttcatgag ccagctcgat cttgccggca acaccggtgg
    10861 aagcgctggc cacatagttg acgattttgc catcgccatg gtcgatgccc ttcaacacca
    10921 cgttcttggc acccaacttc agcagagcac caagcagctc gttaaccgtg gcctcatcaa
    10981 tattctggcc aggatagtca cgcttggtga gaatactcgc ttcggtgagg ttcggcatca
    11041 acacgtcggc accatcggcc agagcgccca ttgcctcgca cagctccggt gtatacgtgg
    11101 ggtacatttc gccggcgtct cccatcaccg ggtcaaccag acgcagcgcg ttcggatatt
    11161 cacggtagag acgctgaatg atcgccacct gatcggggga gccgaggaag cctgaataca
    11221 cgccatccag ttccacgtct tccttctgcc aggcatccaa gtaaccggag agaatatccg
    11281 tggtgtcgtg gaacgtgaac actgcatagc gcgtgtgcgc cgagaacagg gcggtcggca
    11341 ccgggcacac atcgcagcct gcggccgaga gaatcggaat cgcggcggtc agcgagcact
    11401 tgccgtagcc gcacatgtcg tgcacggcgg ccacgcgcgg aatatagctc ggatcacggt
    11461 catacagtgt tacatcggtc atgtctgttc gaaccccttc accatgttgg cggaataatt
    11521 cattggcgat gtttgactgt agtcgttcgt catgtaaacc atgtaaccgg gcggcggaaa
    11581 aatgaaacag acgtcatcgc cgagcgggca aaccgtcttg gtgacgggtg gaacaagcaa
    11641 tcatcacgga cacttgagcc atgcgcgaaa ggcatggtag cgatatcacc gtgaccgcag
    11701 tcgaacgtga aagcgcatgc gcgcggcccg gcgtgtcgcg ataatttcaa cgacttttcc
    11761 gtgactcttg acagtttctc acgtcaatga ttccaaggct ttataagccc ctataggcaa
    11821 gcccgataac gttcggcttg cgtcgcgcgg cccaagcgtc gtaacttcat aaccaacacc
    11881 tcgccaacca cccgaacacg gcaggcgggc ggcaaggaaa aatcctcgcg acctagcata
    11941 accaaggaga aatacccatg gccgagaaca gcaaaaagta ccgttttgaa accctgcagc
    12001 tgcatgtggg ccaggagcag gccgacccgg ccaccgattc ccgcgcagtg ccgatctacg
    12061 ccaccacctc ctacgtcttc cacaacttcg atcatgccga ggcccgattc ggccttgccg
    12121 acccgggcaa catctacggc cgtctgacca acaccaccca gggtgtcttt gaggaccgca
    12181 tcgccgccct tgaaggtggt accgcaggcc ttgccgtcgc ctccggtgca gccgccgtgg
    12241 aatacgcggt gcgcaacatc acccagtccg gtgatcacat cgtcgccgcc aagaacatct
    12301 acggcggcac cttcaacctg ctgcgccaca ccctgccgcg cgacggcatc accaccacct
    12361 tcgtttccgc cgagaacccg caggagttcg aggatgccat tcaggagaac accaagctcg
    12421 tctacttcga gaccttcggc aacccgaacg ctgatctgcc ggacttcgag gcaatctccg
    12481 aaatcgccca caagcacaac ctgccggtga tcgtggacaa caccttcgcc accccgtacc
    12541 tgttccgccc gctggagcac ggcgccgacg tggtggttga atccgccacc aagttcatcg
    12601 gcggccacgg caccactttg ggtggtgtga ttgttgaagg cggcaacttc gactggaatg
    12661 cggttccggg caagttcccg accctgaccg agccggaccc ctcctaccac ggcctgaact
    12721 tctacgaggc tctcggcggc accgccttcg tgacccgtat ccgcgccatc ctgctgcgcg
    12781 ataccggtgc caccctgtcc ccgttcgccg cattcctgct gctgcagggc accgaaaccc
    12841 tgtccctgcg tgttgagcgc cacgtccaga acgcgctgaa ggtcgtcgag tacctgcaga
    12901 ccgtgccgga agtcgagtcc gtttcccacc cgtccatccc gggccgtccg gatcacgacc
    12961 tgtacgagaa gtacttcccg aacggagcag gctccatctt caccttcgat atcaagggcg
    13021 gaaaggatgc agctcgcgtc ttcatcgaca atctgcacct gttctctctg cttgccaatg
    13081 tggccgacgc aaagtccctc gtcatccacc cggcttccac cacgcactcc caggagacct
    13141 tggaagagct cgaggaccag ggcattcacc agggcaccat ccgcctgtcc atcggcaccg
    13201 agaacatcga ggatatcctc gatgacctga agggcggctt cgaagccctt cgcgcttccg
    13261 gcttggccaa gtgaggtcga cagaaaggtt gacagcccga tgagaagggg cgcgatgcta
    13321 atggggtgca tctcgaatca tcgagccgca tggggtgcct tccgcctgat cgcttgaccc
    13381 aaggagtagg aagctcgcac tgacgtcatg cagtgcgggc tttcttgcgt ctgtatgcct
    13441 cacacaaaaa tgaccgtcgc ccaaaaatgt gtgaggcaaa cgcacatcat cacccaatca
    13501 cacatgttga caatccgcga tatttcgccg attgtcggat gtcgttgttc gttttatatt
    13561 cggttggcct cacactgttt gcgcagaggc atgaatagtg tgagacctga gacgacataa
    13621 tcctcaagga tgagggccgg cgcgtggccg accgcccaat tcagtctggc gcacgatggg
    13681 gcgtgccgtt atttcttcat aagttggaat cgtcatccgg gcataaggcc cggccaaata
    13741 tggagagaca ttatgaacgt gcagaacccg gccgcatcgc gcggcatcgc tattcaggcc
    13801 gtcgacttgg tcaagaacta cggcaccggc agcaatatgg tccatgccct gcgcggcgtg
    13861 aacgtgagtt tcgaacgcgg cgaattcacc gccatcatgg gcccgtccgg ctccggcaaa
    13921 tccacgctta tgcacacgct cgccggcctc gactccgcca catccgggca tatccttttc
    13981 ggcggggcag acctgacccg catggacgac aagcagctca ccttgctgcg tcgccacaag
    14041 atcggcttca tcttccaaag cttcaacctg ctgcccatgt tcaccgccga acagaacatc
    14101 ctcatgccac tgactctcgc cggagacaag cccgaccgcg cttggttcga cctgctcgtc
    14161 gaaaccctgg ggctgcagca gcgcctgaac caccgaccga atgaactgtc cggtggccag
    14221 cagcagcgcg tggccatcgc ccgcgcgctg attaccaagc cgaagctggt gttcgctgac
    14281 gagccgaccg gcaacctcga ctccgtttcc agcgccgaag tgctcggctt cctgaagcgt
    14341 tcggtcaacg agcttggcca gaccatcgtc atggtcacgc acgatgcggt ggccgcctcc
    14401 tatgccgacc gtgccatcgt attcgccgac ggacagatcg tggccgacga ggcgaacccc
    14461 accgccgaaa cgatgaacga gctgcttatg gccgaacgcg aacgtgccac gcgcactgcc
    14521 gtcaccggca cacgcgccga cacgctcgcc cgtcttgccg gcgtaaagga tgtgcccaac
    14581 ctgcccatca ccgacgctcc attgcccccg gctgggagaa ccggcaccat gcgccatgcc
    14641 cgcgtcgctg cacagcacgc ttgctgagcc ggaaagcgag agacaggaca cccccatgtt
    14701 ttccatcact ctgaaactta tgaagagaag cgccaggatg ctgattccgg caggcatcgc
    14761 catcctgatc ggcactgcgt tcatcgccgc taccttcctg ttcggcaacg cgatgaacga
    14821 tgcgcttgcc gcgcagagca cagcacagct cggcggcgcg aactacgtga tcgccccgga
    14881 cgccggcaag gacctgaccg ataaggacca ggactacatc tacacgcgca cgtttaacga
    14941 cttccagctt ggccgcatcc gcgccaccga aggcgtcaag gacgcacgtg ccggctacgc
    15001 gggttctgtg accgtaaccc gtggcaacaa gcatgccaac agctacgtca tcaccaccgc
    15061 cgcaaaacgc acgctgctgc cggtcaccat cacgcaagga gaccggccgg cggacagcaa
    15121 cgagatcgcc ctgaccaagt ccgtggccga ccagctcggc gtcaaggtag gagaccgtgt
    15181 gaccgtcaac tcgcaggcgg cgcagtatgc ggacaagacc ggcgattcgg ccggtgacgt
    15241 cggtgataag tcggtccaga acgccgatga cgcgagcgcg cacaacggtg attccgataa
    15301 cgcgtccggc gtgtccgcct catccgatgg cgccaacact gccgactccg gcatgaccgt
    15361 gcgcgtggtc ggtctgaccg acgatccgaa cggcgcctac ccctactacg gcggcgcctc
    15421 cgtgctctcc gacaacgtga tcgccgcgat gggcggcagc gacgatttcg acgaactgcc
    15481 taccctcatg atctatctcg acatcgatgg cgaggacgat gaggccgcaa cggccgcggt
    15541 cgcacggatc aacgccctgc tccccaagca tttcagcgtc cagtcccgag ccacatacgc
    15601 cgaacgatcc atcgcgagca tgagcgcggg cgaaaccagt atcaccacca tcttcctgct
    15661 gagcttcggc atgctcgcca tgctggtcgc cgcgctcgtc atcgccaaca ccttccaagt
    15721 gctcgtggca cagcgccgcc gcacacttgc cctgctgcgc accatcggcg cgaataaaag
    15781 ccagttgtat gtctccgtgc tgttcgaggc cggcgtgctg gggctcatcg cctccatatt
    15841 gggtgtgggc ctcggcatcg ccctcatgga agcgctgtgc cggtccggcc tcatgcaggc
    15901 cgccgacatg aacatgcgac tggtactatc cggtccggtg ttcacggtgc cgatggcgtt
    15961 cggcatcatt atgacggtga ttgcctcgct cggctccgcg cgttctgcta ccgccgtcac
    16021 cccgttggaa gcgttgcgac ccatcgaact gaccgacaca cgacgggccg gtgtggtccg
    16081 cgccgtgatt tccatgctgc tgattgtggc cggcgtggca ctgtgcgcat tctctgtatg
    16141 gcagatgtcc gagaaaatcg ccggacgtga ttcaatggcc gacaagcagt atccgctggt
    16201 gttgctcgcc gccatcatcg gatgtgcatt gatcttcctt ggactggtgc tttccgccac
    16261 gttctggcta ccggtgctca tgcgcggcgt gggcgcgctg gttgcactgg ccggtccgtc
    16321 cgccaaagtg gcacatgcga acattcagaa gaacccgcgc cgcgtggccg ccaccggtgc
    16381 cgcactgctt atcggcgtga cgctggtctc caccatcgcc accggtgccg ccagcgccaa
    16441 gcaaaccatg aacgaggcgc tgaccacgcg ctacagcgtc gacatgattg ccgctggcac
    16501 cgatatgact ggcaaacagg ccagcg
//
