MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
ADB92571.1 CcbS BGC0001225 NRP 42.0 98.5 295.0 3.91e-97
ABX00614.1 LmbS BGC0000907 Other 42.0 96.9 277.0 2.86e-90
KKY62497.1 pyridoxal-5'-phosphate-dependent_protein BGC0001747 Other 40.0 98.7 258.0 7.47e-83
QEG98947.1 ant12 BGC0002042 NRP 37.0 96.1 219.0 1.13e-67
AIS24857.1 dst12 BGC0001147 NRP 36.0 95.6 213.0 2.69e-65
CAJ88616.1 putative_lipopolysaccharide_biosynthesis_protein BGC0000327 NRP 37.0 97.2 212.0 5.05e-65
QWF78538.1 dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose_transaminase BGC0002142 Polyketide 39.0 92.5 211.0 6.84e-65
AAK68921.1 putative_amino_sugar_synthetase BGC0001410 Saccharide 33.0 103.3 211.0 1.98e-64
ACB37737.1 NDP-deoxyhexose_3-aminotransferase BGC0000162 Polyketide 38.0 95.9 205.0 2.68e-62
WP_053138492.1 DegT/DnrJ/EryC1/StrS_family_aminotransferase BGC0002033 Polyketide 34.0 97.9 204.0 6.73e-62
CBH32794.1 putative_aminotransferase BGC0000263 Polyketide 38.0 92.3 203.0 1.33e-61
AGI99500.1 sugar_3-aminotransferase BGC0001004 Polyketide:Modular type I polyketide 37.0 95.6 201.0 8.13e-61
QFU80905.1 sugar_3-aminotransferase BGC0002550 Polyketide 37.0 95.6 201.0 8.13e-61
AGC09481.1 LobD3 BGC0001183 Polyketide 36.0 95.6 198.0 8.83e-60
AKG06372.1 aminotransferase_DesV BGC0001830 Polyketide 36.0 98.7 198.0 1.21e-59
MUL41469.1 DegT/DnrJ/EryC1/StrS_family_aminotransferase BGC0002045 Polyketide:Type II polyketide 36.0 96.1 197.0 2.45e-59
AVO00806.1 May7 BGC0001661 Polyketide 35.0 98.2 196.0 4.85e-59
AKA59113.1 C3_transaminase BGC0001817 Other 36.0 96.7 196.0 6.14e-59
BAL90279.1 putative_aminotransferase BGC0002021 Polyketide 36.0 96.4 196.0 9.82e-59
ctg1_18 BGC0001931 Polyketide 39.0 93.1 196.0 1.32e-58
QBK46623.1 HrsE BGC0001960 Polyketide 35.0 97.2 195.0 1.83e-58
AHH99939.1 aminotransferase BGC0000002 Polyketide 35.0 95.6 194.0 4.73e-58
BBM96645.1 NDP-hexose_aminotransferase BGC0002452 Polyketide 38.0 90.5 194.0 7.68e-58
BAC57033.1 transaminase BGC0000102 Polyketide 37.0 95.9 193.0 9.27e-58
AIE77082.1 putative_C-3_aminotransferase BGC0000418 NRP 36.0 95.1 192.0 1.84e-57
ACB46490.1 sugar_3-aminotransferase BGC0000082 Polyketide 35.0 95.6 192.0 2.04e-57
BAC79028.1 NDP-deoxyhexose_3-aminotransferase BGC0000245 Polyketide 35.0 96.1 192.0 2.21e-57
AHA81993.1 NDP-hexose-3-aminotransferase BGC0000199 Polyketide:Type II polyketide+Saccharide:Hybrid/tailoring saccharide 34.0 96.1 192.0 2.91e-57
BAB72037.1 AclZ BGC0000191 Polyketide 35.0 96.1 191.0 3.64e-57
ABV98195.1 DegT/DnrJ/EryC1/StrS_aminotransferase BGC0000827 Alkaloid 35.0 96.7 191.0 5.66e-57
BAC55216.1 aminotransferase BGC0000825 Alkaloid 36.0 94.9 190.0 1.01e-56
CAC48376.1 putative_C-3_amino_transferase BGC0000311 NRP 36.0 95.1 189.0 1.99e-56
RDI34280.1 dTDP-4-amino-4,6-dideoxygalactose_transaminase BGC0002662 NRP 34.0 95.1 189.0 2.7e-56
EME52967.1 glutamine--scyllo-inositol_transaminase BGC0001460 NRP:Glycopeptide 35.0 95.6 189.0 2.79e-56
WP_030957322.1 aminotransferase BGC0001852 Polyketide:Type II polyketide+Saccharide:Hybrid/tailoring saccharide 35.0 95.4 188.0 5.51e-56
AAQ82556.1 FscMII BGC0000034 NRP+Polyketide 35.0 98.2 187.0 7.01e-56
QLJ99346.1 DegT/DnrJ/EryC1/StrS_family_aminotransferase BGC0002088 Polyketide+Saccharide:Oligosaccharide 35.0 96.4 188.0 8.56e-56
AIG79218.1 C-3_aminotransferase BGC0000419 Saccharide+NRP:Glycopeptide 35.0 95.6 187.0 1.53e-55
OLZ52436.1 daunorubicin_biosynthesis_sensory_transduction_protein_DnrJ BGC0001462 NRP:Glycopeptide 35.0 95.1 187.0 1.53e-55
AFV52158.1 sugar_aminotransferase BGC0000081 NRP+Polyketide:Iterative type I polyketide+Polyketide:Enediyne type I polyketide 33.0 97.9 187.0 2.11e-55
OKA09443.1 daunorubicin_biosynthesis_sensory_transduction_protein_DnrJ BGC0001459 NRP:Glycopeptide 36.0 95.6 187.0 2.14e-55
AAF73462.1 putative_aminotransferase BGC0000193 Polyketide 37.0 83.3 185.0 5.68e-55
BAV57445.1 Glutamine--scyllo-inositol_transaminase BGC0001818 NRP 39.0 81.2 187.0 9.2e-55
AAG13910.1 TDP-3-keto-6-deoxyhexose_3-aminotransaminase BGC0000092 Polyketide 35.0 96.1 185.0 9.43e-55
AEI58886.1 C-3_amino_transferase BGC0000455 NRP 35.0 95.1 185.0 1.17e-54
QBG82538.1 dTDP-4-amino-4,6-dideoxygalactose_transaminase BGC0002587 Polyketide 33.0 97.2 184.0 2.15e-54
OJF16277.1 AceD2 BGC0001491 Polyketide 35.0 97.9 183.0 2.94e-54
WP_031146979.1 aminotransferase BGC0001851 Polyketide:Type II polyketide+Saccharide:Hybrid/tailoring saccharide 34.0 95.4 183.0 6.36e-54
AGS77316.1 Aminotransferase BGC0001178 NRP:Glycopeptide 35.0 96.1 183.0 7.02e-54
WP_053138498.1 DegT/DnrJ/EryC1/StrS_family_aminotransferase BGC0002033 Polyketide 38.0 89.5 183.0 7.23e-54
ACN39737.1 SibN BGC0000428 NRP 34.0 96.9 183.0 7.41e-54
EFG04597.1 Staurosporine_biosynthesis_aminotransferase_StaI BGC0000826 Alkaloid 34.0 95.9 182.0 8.92e-54
WP_081238286.1 DegT/DnrJ/EryC1/StrS_family_aminotransferase BGC0002105 Polyketide 35.0 96.4 181.0 2.25e-53
QHZ32182.1 dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose_transaminase BGC0002047 Polyketide 33.0 96.9 181.0 5.35e-53
AAC68680.1 transaminase BGC0000898 Saccharide:Hybrid/tailoring saccharide 35.0 93.8 181.0 6.2e-53
WP_102918850.1 DegT/DnrJ/EryC1/StrS_family_aminotransferase BGC0002104 NRP+Polyketide 34.0 96.4 180.0 6.23e-53
ABV83226.1 CppDII BGC0000116 Polyketide 35.0 96.7 179.0 8.75e-53
AAP85347.1 aminotransferase BGC0000233 Polyketide 32.0 95.9 179.0 1.44e-52
BAW27688.1 aminotransferase BGC0001764 NRP 39.0 77.9 181.0 1.48e-52
QSE03588.1 Lcm5 BGC0002333 Polyketide 35.0 96.4 179.0 1.72e-52
AAM27543.1 BGC0000784 Saccharide 34.0 93.8 177.0 5.81e-52
AAF71772.1 nysDII BGC0000115 Polyketide:Modular type I polyketide+Saccharide:Hybrid/tailoring saccharide 35.0 95.4 177.0 6.68e-52
CAJ88190.1 putative_aminotransferase BGC0000151 Polyketide:Modular type I polyketide+Saccharide:Hybrid/tailoring saccharide 33.0 96.1 177.0 7.26e-52
OLZ50905.1 daunorubicin_biosynthesis_sensory_transduction_protein_DnrJ BGC0001461 NRP:Glycopeptide 33.0 96.7 176.0 2e-51
AFD30956.1 CrmC BGC0000966 NRP+Polyketide 33.0 99.0 177.0 2.18e-51
AGN74881.1 L-lysine_2-aminotransferase BGC0000459 NRP:Cyclic depsipeptide+Polyketide:Trans-AT type I polyketide 32.0 94.9 178.0 2.27e-51
AAM88356.1 NbmG BGC0000899 Saccharide 34.0 93.6 176.0 2.54e-51
AYA22311.1 KraC BGC0001955 NRP 33.0 96.7 176.0 2.8e-51
BAG50460.1 WblQ_protein BGC0000780 Saccharide 33.0 95.4 176.0 3.83e-51
AAR16518.1 RimF BGC0000138 Polyketide 35.0 95.6 174.0 1.4e-50
WP_003985475.1 DegT/DnrJ/EryC1/StrS_family_aminotransferase BGC0002106 Polyketide 35.0 95.6 174.0 1.4e-50
ARF06216.1 glutamine--scyllo-inositol_transaminase BGC0001593 NRP 39.0 77.9 176.0 1.62e-50
AVX51104.1 nysDII BGC0001709 Polyketide 35.0 95.4 173.0 1.97e-50
QIZ24107.1 aminotransferase BGC0002540 Polyketide 34.0 96.9 173.0 2.76e-50
CAC20927.1 PimC_protein BGC0000125 Polyketide 34.0 95.6 171.0 1.06e-49
AQT01387.1 SgnC BGC0001690 Polyketide 34.0 95.6 171.0 1.06e-49
CAB57207.1 putative_amino-transferase BGC0000760 Saccharide 33.0 100.5 172.0 1.37e-49
AGC09502.1 LobA8 BGC0001183 Polyketide 33.0 97.9 172.0 1.63e-49
QJU69501.1 LooS13 BGC0002460 Alkaloid 35.0 76.3 171.0 2.09e-49
ACB46495.1 sugar_4-aminotransferase BGC0000082 Polyketide 32.0 97.9 171.0 2.23e-49
ADX66467.1 ScnC BGC0000108 Polyketide 34.0 95.6 170.0 2.93e-49
WP_029025944.1 DegT/DnrJ/EryC1/StrS_family_aminotransferase BGC0000198 Polyketide:Type II polyketide+Saccharide:Hybrid/tailoring saccharide 31.0 97.4 171.0 3.35e-49
CAH18560.1 putative_L-glutamine:hexose-3''-aminotransferase,_TobS2 BGC0000721 Saccharide 36.0 85.3 169.0 2.49e-48
AHA81998.1 NDP-hexose-4-aminotransferase BGC0000199 Polyketide:Type II polyketide+Saccharide:Hybrid/tailoring saccharide 32.0 97.2 168.0 3.36e-48
ABS50480.1 NapB3 BGC0000652 Terpene 32.0 98.5 170.0 4.52e-48
AGH68904.1 aminotransferase BGC0001083 Terpene+Polyketide:Type III polyketide 30.0 95.6 167.0 7.2e-48
AAC98613.1 perosamine_synthetase BGC0000772 Saccharide 31.0 95.1 167.0 8.7e-48
AGI99479.1 sugar_4-aminotransferase BGC0001004 Polyketide:Modular type I polyketide 32.0 97.7 167.0 9.2e-48
QFU80883.1 sugar_4-aminotransferase BGC0002550 Polyketide 32.0 97.7 167.0 9.2e-48
AAU93788.2 transaminase BGC0000054 Polyketide 35.0 92.0 166.0 1.34e-47
ARD70899.1 deoxysugar_aminotransferase BGC0001693 Polyketide 32.0 96.9 162.0 8.25e-46
BAD20764.1 aminotransferase BGC0000702 Saccharide 34.0 81.2 162.0 1.08e-45
QEU90636.1 DegT/DnrJ/EryC1/StrS_family_aminotransferase BGC0000703 Saccharide 34.0 81.2 162.0 1.08e-45
CAE46943.1 putative_glutamine--scyllo-inosose_aminotransferase BGC0000704 Saccharide 34.0 81.2 162.0 1.08e-45
CAF31593.1 putative_pyridoxalphosphate-dependent_aminotransferase_class_IV BGC0000705 Saccharide 34.0 81.2 162.0 1.08e-45
ABM21742.1 PdmU BGC0000256 Polyketide 31.0 96.9 160.0 2.29e-45
BAE78971.1 hypothetical_protein BGC0001078 Terpene+Polyketide 30.0 97.4 160.0 2.98e-45
AHW57776.1 PgaC1 BGC0000262 Polyketide:Type II polyketide+Saccharide:Hybrid/tailoring saccharide 31.0 95.6 160.0 3.73e-45
ABY83158.1 Azi19 BGC0000960 NRP+Polyketide 35.0 77.4 160.0 1.2e-44
RDI34279.1 dTDP-4-amino-4,6-dideoxygalactose_transaminase BGC0002662 NRP 34.0 100.8 156.0 1.16e-43
BBA97271.1 putative_NDP-hexose_3-dehydratase BGC0002383 Polyketide 32.0 98.2 155.0 5.68e-43
BAV17013.1 putative_NDP-hexose_dehydratase BGC0001384 Polyketide 31.0 97.4 155.0 8.2e-43
ADI71459.1 putative_sugar_3-dehydrase BGC0000203 Polyketide 32.0 97.9 154.0 1.62e-42
CAF31367.1 putative_NDP-hexose_3-dehydratase BGC0000268 Polyketide 31.0 97.4 154.0 2.13e-42
AAO78482.1 nucleotide_sugar_transaminase BGC0001654 Saccharide 32.0 77.1 152.0 3.04e-42
WP_053138458.1 lipopolysaccharide_biosynthesis_protein_RfbH BGC0002033 Polyketide 31.0 86.9 153.0 4.04e-42
AHW57788.1 PgaQ BGC0000262 Polyketide:Type II polyketide+Saccharide:Hybrid/tailoring saccharide 30.0 102.1 153.0 4.12e-42
TRO56989.1 lipopolysaccharide_biosynthesis_protein_RfbH BGC0002361 Polyketide+Saccharide 31.0 97.4 153.0 5.72e-42
QTA30598.1 lipopolysaccharide_biosynthesis_protein_RfbH BGC0002143 Polyketide 31.0 97.9 152.0 8.72e-42
AAS79442.1 putative_D-chalcose_pathway_component BGC0000035 Polyketide 32.0 93.1 152.0 8.9e-42
ARO44653.1 NDP-hexose_3,4-dehydratase BGC0001769 Polyketide 30.0 97.4 152.0 1.11e-41
OWA01600.1 lipopolysaccharide_biosynthesis_protein_RfbH BGC0001439 Polyketide+Saccharide:Hybrid/tailoring saccharide 29.0 104.4 152.0 1.57e-41
MBW8699697.1 GDP-perosamine_synthase BGC0002140 Polyketide 30.0 97.4 151.0 2.14e-41
QBK46627.1 HrsA4 BGC0001960 Polyketide 30.0 96.9 150.0 3.99e-41
AAF72550.1 NDP-hexose_3,4-dehydratase_UrdQ BGC0000278 Polyketide 30.0 97.4 150.0 4.13e-41
AGO50624.1 NDP-hexose_3,4-dehydratase BGC0000229 Polyketide:Type II polyketide+Saccharide:Hybrid/tailoring saccharide 30.0 97.4 150.0 5.74e-41
ABB69735.1 PlaA1 BGC0000654 Terpene+Saccharide:Hybrid/tailoring saccharide 31.0 97.4 150.0 5.74e-41
ctg1_29 BGC0001931 Polyketide 28.0 103.3 150.0 7.84e-41
AWR88424.1 putative_DegT/DnrJ/EryC1/StrS_aminotransferase BGC0001522 Polyketide 30.0 95.6 149.0 1.05e-40
ABB52533.1 3,4-dehydratase-like_protein BGC0000047 Polyketide 31.0 92.5 149.0 1.25e-40
sipS13 dTDP-4-dehydro-6-deoxyglucose_aminotransferase BGC0001452 Polyketide 30.0 95.6 148.0 2.04e-40
ABX71129.1 Lct46 BGC0000238 Polyketide 30.0 96.9 148.0 2.62e-40
ACK77744.1 putative_NDP-hexose_3,4-dehydratase BGC0000727 Saccharide 30.0 97.9 148.0 2.97e-40
CAA09644.1 putative_CDP-4-keto-6-deoxyglucose-3-dehydratase_(E1) BGC0000227 Polyketide:Type II polyketide 30.0 98.2 147.0 7.81e-40
OWA25236.1 lipopolysaccharide_biosynthesis_protein_RfbH BGC0001438 Polyketide+Saccharide:Hybrid/tailoring saccharide 30.0 98.7 147.0 8.23e-40
ANC94983.1 AlmBII BGC0001396 Polyketide 31.0 92.5 145.0 1.69e-39
QEA08895.1 JenG3 BGC0002559 Polyketide 29.0 105.9 145.0 2.95e-39
ADM46366.1 3-amino-5-hydroxybenzoic_acid_synthase BGC0000106 Polyketide 38.0 63.5 144.0 3.28e-39
AKD43519.1 NDP-hexose_3,4-dehydratase BGC0001409 Polyketide 29.0 97.9 145.0 3.89e-39
QBG82539.1 NDP-hexose_3,4-dehydratase BGC0002587 Polyketide 30.0 97.4 145.0 4.45e-39
ACN64825.1 PokS5 BGC0001061 Polyketide:Iterative type I polyketide+Polyketide:Type II polyketide+Saccharide:Hybrid/tailoring saccharide 29.0 97.9 145.0 5.49e-39
BCK51624.1 putative_glutamine-scyllo-inositol_transaminase BGC0002520 Polyketide 38.0 63.8 143.0 8.99e-39
AYU66262.1 TjhB6 BGC0002461 Polyketide 30.0 97.4 144.0 1.51e-38
AAM54102.1 3-amino-5-hydroxybenzoate_synthase BGC0000020 Polyketide 37.0 67.1 141.0 4.75e-38
ATY46602.1 AHBA_synthase BGC0001666 Polyketide 38.0 65.8 141.0 4.75e-38
AAL24451.1 RdmI BGC0000265 Polyketide 29.0 96.9 142.0 5.5e-38
AQZ37112.1 lipopolysaccharide_biosynthesis_protein_RffA BGC0001511 Polyketide 37.0 67.1 141.0 6.61e-38
AFV30265.1 AHBA_synthase BGC0000075 Polyketide 35.0 63.8 140.0 9.18e-38
KDN80049.1 lipopolysaccharide_biosynthesis_protein_RfbH BGC0001074 Saccharide+Polyketide 28.0 106.2 141.0 1.06e-37
AEF16041.1 NDP-sugar_aminotransferase BGC0000953 Saccharide:Aminoglycoside 29.0 96.7 140.0 1.3e-37
BAV55999.1 NDP-sugar_aminotransferase BGC0001597 Polyketide 32.0 76.3 139.0 1.71e-37
QES95470.1 AHBA_synthase BGC0002453 Polyketide 37.0 63.8 140.0 1.94e-37
ABV97160.1 Glutamine--scyllo-inositol_transaminase BGC0000137 Polyketide 37.0 63.8 139.0 2.46e-37
ACF35452.1 mbcE BGC0000090 Polyketide 39.0 58.9 139.0 4.74e-37
AAC01720.1 RifK BGC0000136 Polyketide 36.0 63.8 137.0 1.76e-36
QKV49794.1 lipopolysaccharide_biosynthesis_protein_RfbH BGC0002526 Polyketide 28.0 97.7 138.0 2.01e-36
QDG00814.1 NDP-hexose_34-dehydratase BGC0002028 Polyketide 30.0 99.2 137.0 2.79e-36
ACN38344.1 2-deoxy-scyllo-inosose_aminotransferase BGC0000714 Saccharide 37.0 65.3 137.0 3.08e-36
AAP42864.1 NanG3 BGC0000105 Polyketide 28.0 97.4 137.0 3.85e-36
CAI94689.1 putative_AHBA_synthase BGC0000141 Polyketide 38.0 58.9 136.0 4.54e-36
CQR60488.1 RifK_homologue,_3-amino-5-hydroxy_benzoic_acid_(AHBA)_synthase BGC0001287 Polyketide 38.0 63.8 136.0 4.54e-36
AAD32723.1 MitA BGC0000915 Other:Aminocoumarin 39.0 64.3 136.0 4.7e-36
AWH12658.1 RmpK BGC0001759 Polyketide 36.0 63.8 136.0 4.7e-36
AAD13547.1 NDP-hexose_3,4-dehydratase_homolog BGC0000239 Polyketide:Type II polyketide+Saccharide:Hybrid/tailoring saccharide 29.0 97.7 136.0 1.02e-35
CAE06512.2 putative_L-glutamine:2-deoxy-scyllo-inosose_aminotransferase BGC0000689 Saccharide 37.0 65.3 135.0 1.56e-35
CAF31430.1 putative_L-glutamine:ketocyclitol_aminotransferase BGC0000696 Saccharide 37.0 65.3 135.0 1.56e-35
ARV75707.1 1-keto-2-deoxy-scyllo-inosamine_aminotransferase BGC0001603 Saccharide 37.0 65.3 135.0 1.56e-35
CCP20043.1 divG_protein BGC0001119 Polyketide:Modular type I polyketide 37.0 64.0 134.0 1.71e-35
ATJ00772.1 RfbH/_NDP-hexose_3,4-dehydratase BGC0001568 Polyketide 28.0 96.9 135.0 1.92e-35
QIE07119.1 OvmG BGC0001719 Polyketide 37.0 64.0 134.0 2.5e-35
WP_018891731.1 lipopolysaccharide_biosynthesis_protein_RfbH BGC0001558 Polyketide 28.0 96.9 135.0 2.66e-35
BAP34744.1 NDP-hexose-3,4-dehydratase BGC0000078 Polyketide 28.0 105.9 135.0 3.13e-35
RIH60569.1 hypothetical_protein BGC0002652 Other+Saccharide 34.0 68.1 131.0 1.24e-34
ACP19374.1 SaqQ BGC0000267 Polyketide:Type II polyketide+Saccharide:Oligosaccharide 29.0 97.7 133.0 1.4e-34
CAF31854.1 putative_bifunctional_L-glutamine:2-deoxy_ketocyclitol_aminotransferase_I_and_II BGC0000699 Saccharide 35.0 67.4 132.0 1.88e-34
AKA59099.1 NDP-hexose-3-dehydratase BGC0001619 Polyketide 29.0 98.2 132.0 1.93e-34
AWH12647.1 Rmp6 BGC0001759 Polyketide 28.0 106.9 131.0 5.01e-34
AHH25589.1 AHBA_synthase BGC0000957 NRP+Polyketide 36.0 57.3 129.0 6.16e-34
AAC01730.1 putative_dNTP-hexose_dehydratase BGC0000136 Polyketide 28.0 106.9 129.0 2.51e-33
ASZ00156.1 AHBA_synthase BGC0001785 Polyketide 40.0 48.8 127.0 5.9e-33
CAI47660.1 putative_aminotransferase BGC0000692 Saccharide 30.0 93.1 123.0 2.31e-31
BAG22752.1 putative_L-alanine:N-amidino-3-keto-scyllo-inosamine_aminotransferase BGC0000724 Saccharide 36.0 57.8 123.0 2.98e-31
CAD27647.1 AtaP4_protein BGC0000873 Other 33.0 69.2 122.0 7.17e-31
QDG00810.1 NDP-hexose_aminotransferase BGC0002028 Polyketide 29.0 76.9 115.0 3.45e-29
ARA90610.1 DegT/DnrJ/EryC1/StrS_aminotransferase BGC0001610 Other 30.0 54.5 82.0 8.13e-17
QWT72282.1 pyridoxal_phosphate-dependent_aminotransferase BGC0002430 NRP+Saccharide 28.0 28.5 50.0 1.73e-06