LOCUS       c00069_gnlPro..        13900 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KIHNPMBG_69.
ACCESSION   c00069_gnlPro..
VERSION     c00069_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 23:52:24
            Original ID  :: gnl|Prokka|KIHNPMBG_69
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 28281
            Orig. end    :: 42181
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13900
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[38281:41795]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13514
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13900
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13900
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(2071..3474)
                     /locus_tag="ctg69_16"
                     /transl_table=11
                     /translation="MKAKLLQSTVLWTFLSAATLFVGCSDDEDYRDVDGQSPTLELTSD
                     HIRTLTGYEFKIAGKIADKDGIRSINLQCTELYLDKTIELSALYSEPLYEYNLNYGFTI
                     PEKTKGDSFTIKVTVTDLGGRTATNDVLVTMDGDYTEPVLTPSIGLLSDNINIVLSEGT
                     SKTFRFTAEDNKELDYLELAVPDLEILERQDIEEGEKKGTLNTTVVFPSDKTGTYTLVI
                     RAVDTFGNIAEKNYSVLVSRVKDYENMYLVDFEGTDSKLLTGNDVWGVPMPIERVTNFT
                     YKARCYSPAPNTPIRFITSKYSFSICFGDDKNNPGKLTGISEDVQPIILPEKSYYEINF
                     NTEEGTYTVEAYSPGTPIIDGLKMGFVGGWFDGAKGWDGPKNVYELTQDPDNPHCLTAE
                     LTWSKQDSFDVTITPYNANGDWLEPGWRFDGKNESFATNTNDSSKKVPAGKYTFIFDTH
                     LVQSKLLKK"
     CDS             3694..7716
                     /locus_tag="ctg69_17"
                     /transl_table=11
                     /translation="MKKHIASILFLCLLSVSQSIAQSHSIKRLGIEQGLSNNYVISIAQ
                     DKQGFLWFATEEGLNKFDGTRFITYYKNDLSQSSQGITGNELNRVYADNKRPIIWIATQ
                     RDGLNAYNYNKQAFTAYSHNPDDPHSLITNDVTDIAPSAQHEDGLWISTYYRGIEYLDI
                     NSGQFTHYNKNTVPALSCEQTWTVLDGGDGNLYIGHVGHGFSILSLKDKSVKNFQNHSG
                     DPKSLPGNDVRCLTKDTNGNIWLGTDKGLALFNVADQSFITFKNNKNDRYAALCNRILA
                     IKQLNDGKLWIASELNGITILDLKQSMFLSPEQISLEYIQEGDDSRSLSNASARCIFQD
                     SFDNIWIGTWGGGINFISRKPPLFTTLSYSPIPNNENSLNNKVASSLCTDRQGRIWIGT
                     DGGGINVFEGDKRIAIYRKETGDIPSNFILTALQDSKGNLWFGSFQGGISYYDTRNKRF
                     RSISLMGQYNQDVRTIYEDTQHNIWVGYSGGIIVLNPLNMEIIRHYNTENSELHSNFVR
                     SIAQDEKGRFWIGTFGDGLGVYTPDLQKIKTFVQRDGFCSNTVNQIIQDKHKRMWIGTG
                     EGLVCFPSTDALTYKTYQRKDGLTNTNICAITEDKKGNIWFSNNKGVSCYVTAKDCFYN
                     YGHSDDVPAGSFSSGCVTQNKNGWIYFGSINGVCCFNPDIAMNEQPTPSAVITEMKILG
                     RLSNLENNDMIINLSKGQNVELSHAQNSFGLTFNVQNYSLVNQVEYVYMLKGLENSWYT
                     VNENNSVTFRNIPPGKYEFLIKARVHNQEWPEEATSLTIRVNPPLWLTWWAKLIYILVS
                     ISIIYLILHAYKKKLDLESLYTLEKKNHEQEQELNQERLRFYTNITHELRTPLTLILGP
                     LEDMQKETSLPAKQAQKLSVIHQSALRLLNLINQILEFRKTETQNKKLCVSKGNIAPLI
                     YEIGLKYKELNQKTKIDFQIQIEKEEMLLFFDKEIITIVLDNLISNAIKYTEQGRVTLS
                     LYQTMRNEVAYTEIKVSDTGYGISAEALPHIFDRYYQESGKHQASGTGIGLALVKNLVT
                     LHEGEIRAESIQNEGSTFYISLLTDNIYPNALHADSTEPIQEDTNLEASPEYPQETTLD
                     TGKPILLIVEDNEEIQKYIAESFADSFEVLTAYNGEEGKQQALSRIPDIVVSDIMMPVM
                     DGITLCRQLKEDVRTSHIPVILLTAKDSLQDKEEGYEVGADSYLTKPFSASLLRSRINN
                     LLESRKKLIAQFQTQSVPGNQADLKEKRIVIAEALSKLDNEFIEKITLFWRPLQTMRQK
                     YFSKEKCFNTFFINLIIIKEERNLLKQSLLNSICKKDLQAAVVRTKSFPQFFSHCL"
     CDS             complement(7684..8646)
                     /locus_tag="ctg69_18"
                     /transl_table=11
                     /translation="MLMLRKIVFFLFVFVGLSLFAQQDYMVSSYVRGNFYNRGRISTES
                     LRASDDLIFLNVHPNKDGSLSFENPRVFQGKGVTTWEGLIKSVRAKVKGTKVKIRLGAS
                     SGEWKAMVADEAARTKFAKNIKTVLEKNKLDGIDLDFEWAENEKEYKDYSLAILKMREV
                     LGDKYLFSVSLHPVCYKISKEAIEAVDFISLQCYGPSPVRFPIEKYCSDIQMVLEYGIP
                     KEKLVAGVPFYGVTKDNSKKTEAYFNFVQNGLVTSPAQNEVIYQGDTYVFDGQDNIRIK
                     TRYAKEQKLKGMMSWDLATDLPLSDSRSLLKTMTEELRE"
     CDS             8920..9789
                     /locus_tag="ctg69_19"
                     /transl_table=11
                     /translation="MPGDSFCIQYTNCTGCPKNVENILVYRNLPKGEHIPKDKCTQNCM
                     LFMIKGELLINSEEHPGITLREKQIVLQAIGSKVEILALTDVEYVVYWFNELPLLCEDR
                     YKEMMEQAEAPLTYTPLIMSERLYHLVTSMPEFLAEENPCSKYIDLKCKELVFLITNFY
                     PLPQLGSFFYPISTYTESFHYFVMQNYSNVKNVEEFAHLGGYTTTTFRRLFKNLYGVPV
                     YEWILEKKREGILEDLQHTKMRITEICNRYGFDSLSHFAHFCKDSFGDTPRALRKKAAG
                     GEKIGKVQ"
     CDS             10001..10705
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_20"
                     /sec_met_domain="SucD_FumR (E-value: 1.3e-131, bitscore:
                     426.6, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAGLAALFVIHIIYAFWLTMQNRKARGSERYAVVDKPKTVEWASQN
                     MLVLGLIVIVGLGLHLFNFWAKMQLPELMHNMGMHADTLTLAYAANGAYHIQQTFSSPV
                     YVVLYLVWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKTLICGGAC"
     CDS             10743..12722
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 202.3; E-value:
                     4.6e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_21"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.6e-62, bitscore:
                     202.3, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.8e-37,
                     bitscore: 118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMQDVVIVDGRARGIIAKNLVTGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAVKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHVMWEYVGMGRTAEGLKKGIAELKEIRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLHKEPLVYEAIKVQTRNYKS"
     CDS             12759..13514
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_22"
                     /sec_met_domain="Fer4_7 (E-value: 1.6e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.2e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.1e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIAKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
ORIGIN
        1 caccgacaaa cggtttttca aaaatgccat atcaataccg atattataat cctctacagt
       61 ttcccatcgg atcaatgagt taccaatcga acctaccgct gtaccaatct cacgattacc
      121 accaaataca taatcggcag ctccaatagt agactgataa gccgaattgt caatattctg
      181 attacccaca cgtccccatc ctgcatgaat cttcaagtta tcaaagatat gctgtttttt
      241 catgaatggc tcttctgaaa tacgccatgc tgcagatact gccggaaaag ttgcgtattg
      301 attatctttc atgaatttag aagaaccatc cacacggata gaagcagtca aatagtaacg
      361 gtcgttgtaa ttatacatca cacgtcccag ataagagatc aatgaagaat aggcattcac
      421 gcctgctgtc tgcggattct gcgtaccggc tgaaacataa tgcaggttct cttcattggt
      481 aggagtgcgt tcctttgatc cttccaacca atattcctgg aaacgttcca tcgtataacc
      541 agccatcaca ttcaaattgt gtttatgatt aaaactctta atccagttta ctgtattcgt
      601 ccagttccag tccacccaat tatcggtttt acgatatgct ttgctgtaat cggatttctc
      661 taatgtatcg atattgaaag aaggagtaaa ctcatctgaa atacggaaac gggcattgac
      721 accaaactgt gaacgaataa ccaagccttt aatcggttca atgtttacat acggattggc
      781 taataaacca tactcatcac tatgtttatc catacgggct aattgggcaa ccggattcca
      841 caccaagttg ttgctggaac gggcatagtt gtcgtattca tttgtcgtcc attcactttg
      901 aggacgcatg atcggagttg tggggtccat agccattata tttcccaata aactgggagt
      961 atctgtccaa ttctcatatt tcggggtaaa gtcaatacct gcttttacta tattattaaa
     1021 agtgtattcc atactgaaac gggctgtcag cttttgccag ttacctacgg tgtattgtga
     1081 gtcttgtccg aaataaccaa tattggcaga gtaaagcaac ttatccgtac ctccggagaa
     1141 attaaaatta tagttatgaa tcagtgctgt cttcttcatg ctttcatccc accagtcagt
     1201 accttccgca tctgtgatat tctccttgct gttataacgg ggctctgcat tatcattaat
     1261 ataacgcgcc ttgaacacat attcgtattc ggaagctttt gccatctccg gtttcttcaa
     1321 tgtctgaaaa ccggcagaag cagagaaacc gaattgggta gctccctttt tacctttctt
     1381 ggtagtaata aggacaacac cgttagagcc acgtgtacca taaatagctg ctgctgaagc
     1441 atctttcagc acttgcatgg attcaatatc gttctggtca agaaaattga tattggttcc
     1501 caccggcatt ccatcaacga catacaacgg atcagaacca ttgacggtag ataccccccg
     1561 aataataaca cgaggtgaag tacccggacc gccgccaccg gtaatctgca caccattaat
     1621 ctttccctgt aaggcattca tggcattacc gccagtcagc tttttcagtt catctccttt
     1681 gatagcagat atagagcttg tcaagtcact cttcttcact gcaccatagc cgataacaac
     1741 tacttcatcc aaagcttgtg tatcatcttc catgactaca ttaatgacat tctttccatt
     1801 gactttgact tcttgtgtct tatacccaat catggaaaat acaatagtcg catctttagg
     1861 aacattagtc agtgtgtagt ttccatccag atccgtgaca gtaccatttg tagtaccctt
     1921 caccagaaca gtcaaaccaa tcattggttc tttatcacta gctgcaatag cagtaccagt
     1981 cagacttccc tgctgagcat aaaggctcag cgcaaagaac gataataata aaaatagata
     2041 tcgtttcatg tttttatggc attattttaa ttatttcttc agcaatttag actgaacaag
     2101 atgtgtatca aatataaagg tgtatttacc tgcgggtacc tttttagatg aatcattcgt
     2161 gttagtagca aatgattcgt ttttaccgtc aaaacgccag cctggctcca gccaatcgcc
     2221 attggcatta tagggagtta ttgtcacgtc aaaagaatct tgtttactcc aagtcaattc
     2281 tgcagtgaga caatgcggat tgtccggatc ttgagtcaat tcatagacat tcttaggtcc
     2341 gtcccagcct ttagcgccat caaaccatcc gccaacgaac cccattttaa gtccgtcaat
     2401 aattggtgtt cccggcgaat aagcttctac tgtataggtt ccctcttctg tattaaagtt
     2461 tatttcataa taactctttt cgggtagaat gatcggctgt acatcttcag agataccagt
     2521 taattttccc ggattatttt tatcatcacc aaaacagatg ctgaagctat atttgcttgt
     2581 aatgaaacgg atcggggtat ttggagcagg tgaataacaa cgagccttat aggtgaaatt
     2641 cgttactcgt tctataggca tcggaactcc ccacacgtca ttgcctgtaa gtaatttact
     2701 gtctgttcct tcaaaatcaa ccaaatacat attttcataa tctttcactc tggaaacaag
     2761 tactgaatag ttcttttccg caatattacc gaaagtatcg acagcgcgta taaccaatgt
     2821 ataggtccca gtcttatcag aaggaaatac aacagtagta ttcaatgttc ctttcttctc
     2881 tccttcttca atatcctgac gttccaagat ttccaaatca ggaacagcta attccaaata
     2941 atccaattcc ttattatctt ctgcagtgaa ccggaatgtt ttagaagtac cttcggacaa
     3001 cacaatatta atattatcac ttaaaagacc aatagacgga gtcaagactg gttctgtata
     3061 atcaccatcc atcgtaacca ggacatcatt tgttgctgta cgcccaccta aatcggtaac
     3121 tgttaccttt atagtaaaac tgtcaccttt cgttttttca ggaatagtga aaccataatt
     3181 cagattatac tcatacaatg gttctgaata aagagccgac aattcaattg tcttgtccaa
     3241 gtaaagctct gtacattgta gattgataga acgaataccg tctttatctg caattttacc
     3301 tgcaatttta aattcatagc ctgtcaatgt acggatatga tcggacgtta actcaagagt
     3361 tggagattgt ccgtctacat ctctatagtc ctcatcgtca ctacatccaa caaacaaggt
     3421 cgctgctgaa aggaaagtcc acaaaaccgt gctttgcaac aatttagctt tcataataat
     3481 tagtatttaa tgattaatat tatctcggta cgacttctca atatataaaa tatcggcaaa
     3541 tcgacatgac aaatgtagac gattccaact atataaaccg ataaaaatca tgcagagaag
     3601 ctacataaat cgtgcaatgc acgatttgca tactctaaat aaaatattta ttcctatttt
     3661 tgagcttgta aatgaaacga ataattacga attatgaaga aacacattgc ttctatttta
     3721 tttctgtgtc tgctatcagt ttctcaatca atagctcaat cccattctat caaacgattg
     3781 ggcattgaac agggattatc taataattat gtgattagta tcgcacaaga taaacaaggc
     3841 ttcttatggt ttgctacaga agaaggactt aataaattcg acggaacccg tttcattacc
     3901 tattataaga atgacttatc gcaaagtagc cagggaatca ctggtaatga actcaatcgg
     3961 gtatacgctg acaataaacg tcccattata tggatagcga ctcaacggga tggattaaat
     4021 gcatataatt acaacaagca agcatttaca gcttattcac ataatccgga cgatcctcat
     4081 agtttgatta caaatgatgt aacagacatc gctccttctg ctcaacacga agatggcctg
     4141 tggatcagta cttattatag aggcatagaa tatctcgata ttaacagtgg gcagttcact
     4201 cattataaca agaatacagt gccggcctta tcttgtgaac aaacatggac tgtactggac
     4261 ggaggggatg gaaacctata catcggtcat gtcggtcacg gattcagtat tctttcactt
     4321 aaagataaaa gtgtaaaaaa cttccagaat cattcgggag acccgaagag cctgcccggc
     4381 aatgatgtac gatgtctcac taaagataca aacggtaata tatggctcgg gacagataaa
     4441 ggcctggctc ttttcaatgt tgccgatcaa agctttatca cttttaagaa taacaaaaat
     4501 gatagatatg cagccttatg caatcggata ttagctatta aacaattaaa tgacggcaaa
     4561 ctttggatcg cttcagagct taatggcatt actatactgg atctcaaaca aagtatgttt
     4621 ctctcacccg aacagatttc cctcgaatat attcaggaag gcgatgatag ccgaagtctc
     4681 tccaatgcaa gtgcccggtg tatattccaa gattcttttg acaacatctg gataggcaca
     4741 tggggaggag gaatcaattt tatcagcaga aagccaccgc tattcacaac attaagttat
     4801 tctccgattc ctaacaatga aaacagcctg aacaataaag tagcgagcag tctctgtacc
     4861 gacagacaag gacgtatatg gattggaaca gacggaggtg gtatcaatgt atttgaaggg
     4921 gacaaacgta ttgctattta cagaaaagaa acaggagaca tcccctcgaa ttttatattg
     4981 accgctttgc aggattcaaa aggaaatcta tggttcggtt cttttcaagg aggaatcagt
     5041 tattatgata ctcggaataa aagatttcgt tccatctctc tcatgggaca gtacaatcag
     5101 gatgtccgta cgatctacga agatactcaa cacaatatct gggtaggata cagcggagga
     5161 atcattgtat tgaatcccct taatatggaa attatccgac actacaacac agaaaacagt
     5221 gaactacata gcaatttcgt acgttctata gctcaagatg agaaagggcg cttctggatt
     5281 ggaaccttcg gagacggact tggcgtatac acgcctgatc tacagaaaat caagaccttt
     5341 gtccaaaggg atggcttctg ttccaacacc gtcaatcaga tcatacagga taaacacaaa
     5401 agaatgtgga taggaacagg agaagggcta gtatgttttc cttcaaccga tgcattaact
     5461 tacaaaacat atcaacgaaa agatggttta accaatacaa atatctgtgc aataacagaa
     5521 gataagaaag gtaatatatg gtttagcaat aataaaggcg tcagttgcta cgtaactgcc
     5581 aaagattgtt tctataacta tggtcactct gatgatgttc cggcgggaag tttctcaagc
     5641 ggttgtgtaa cgcaaaacaa gaacggatgg atctatttcg gttctatcaa tggcgtatgt
     5701 tgcttcaatc ctgacattgc aatgaatgaa caacccactc catcggccgt tatcacagaa
     5761 atgaaaatac tcggacggtt aagcaatctg gaaaacaatg acatgattat caatttatcc
     5821 aaaggacaga atgtagaact aagtcatgcg caaaatagct ttggacttac atttaacgta
     5881 caaaactatt cactagtcaa ccaagtggaa tatgtttata tgctgaaagg gcttgaaaac
     5941 tcatggtaca ccgtcaatga gaacaacagc gtcactttcc gaaacattcc tccgggaaaa
     6001 tatgaattcc tcatcaaggc acgagtacat aaccaggaat ggccggaaga agctacttca
     6061 cttaccatcc gtgtcaatcc ccctctttgg ctgacatggt gggcaaaact tatctacatt
     6121 ttggtatcta tcagcatcat ttatcttatc ctgcatgcat ataaaaagaa gctggatttg
     6181 gaaagcctct atactttgga aaagaaaaac catgagcagg aacaggaatt gaaccaggaa
     6241 cgtttgcggt tctatactaa tattacccat gagctacgta caccgttgac cttaatcctc
     6301 ggtcctctgg aagatatgca aaaagagacc tcacttccgg caaaacaagc ccagaagtta
     6361 tctgtcatcc atcagagtgc actacggctg ctcaacttga ttaatcaaat attggaattc
     6421 cggaagacag agacacaaaa caagaaattg tgtgtcagca aaggcaatat tgctcctctg
     6481 atctatgaga tagggcttaa atacaaagaa ttaaatcaaa agaccaagat tgatttccag
     6541 attcagatag agaaagaaga aatgctcctt ttctttgata aggaaatcat taccatcgtt
     6601 ttggacaacc tgatttccaa tgcgatcaaa tatacggaac agggacgcgt cactctaagt
     6661 ttgtatcaga caatgcgcaa tgaagttgct tatacggaga taaaagtcag tgacacggga
     6721 tatggaattt ctgctgaagc cctgccacat atttttgacc gttattatca ggaaagcggc
     6781 aaacatcagg catccggtac aggcattggc ttggctttag tgaagaatct agtcacccta
     6841 catgaaggag aaatccgggc agaaagcata caaaacgaag gaagtacttt ctatatcagc
     6901 ctattgacgg ataatatcta tcccaatgct ttacacgcag attctacaga accgattcaa
     6961 gaagatacga atctggaagc aagccccgaa tatccacaag aaaccacact ggataccggc
     7021 aaaccgatcc tgttgattgt agaagacaat gaagagatac agaaatatat cgccgagtcc
     7081 tttgccgatt cgttcgaagt actcaccgcc tacaatggag aagaagggaa gcaacaagct
     7141 cttagccgta tcccggatat tgtagtcagc gatattatga tgcctgtcat ggacggtatc
     7201 actctctgcc ggcaattgaa agaggacgta cggaccagtc atatccctgt catcctattg
     7261 acagccaaag attctctgca agacaaagaa gaaggatatg aggtaggggc cgattcttat
     7321 ctgacaaagc ctttcagtgc ttctctgcta cgcagccgta tcaataatct gctggaatca
     7381 agaaaaaagc tgatagctca attccagaca caatccgttc cgggcaatca ggcggattta
     7441 aaagaaaaac gtatcgtaat cgccgaagct ctaagcaagc tggataatga atttattgag
     7501 aaaatcaccc ttttttggag gccacttcaa acgatgcggc agaagtattt ctctaaagaa
     7561 aagtgtttta acacattctt tataaatctg attataataa aggaggagag gaacctatta
     7621 aaacagagcc tgttaaacag catctgtaaa aaggatttac aagcagcagt cgtgcgaact
     7681 aagtcattcc ctcaattctt cagtcattgt ctttagtaat gacctgctgt cacttaacgg
     7741 caaatccgta gctaaatccc aactcatcat acctttcagc ttctgttcct ttgcataacg
     7801 ggttttgata cgaatgttat cctgaccgtc aaacacataa gtatctccct gatagatcac
     7861 ttcattctgt gcaggactcg taaccaatcc attctgtaca aaattgaaat aagcctctgt
     7921 cttctttgaa ttatctttgg tcaccccata aaaaggaact cctgccacca gtttttcctt
     7981 cggaatacca tactccaata ccatctgtat atccgaacaa tatttctcta tcggaaagcg
     8041 aaccggtgaa ggaccatagc actgaagtga aataaaatca actgcttcaa tagcttcctt
     8101 actaatctta taacaaacag gatgcagaga tacactgaaa agatacttgt ctcccaacac
     8161 ttccctcatc ttcaggatag ccaaactata atctttatat tctttctcat tttccgccca
     8221 ctcaaaatca agatcaatgc catccagttt attcttttcc agtacagtct ttatgttctt
     8281 tgcaaacttc gtacgagcgg cctcatcggc caccatcgct ttccattcgc cactggaagc
     8341 tcccaaacgt attttcactt ttgtaccttt tacttttgca cgaaccgatt taatcaaacc
     8401 ttcccaagtg gtcacccctt ttccctgaaa tacacgtgga ttctcaaatg acaatgatcc
     8461 gtctttatta ggatgaacat tcaagaaaat aaggtcgtca cttgcccgca agctttctgt
     8521 agaaatacga ccacggttgt aaaaattacc ccgcacataa gaactgacca tatagtcttg
     8581 ttgtgcaaac aatgataatc caacaaacac aaaaaggaag aatacaattt ttcttagcat
     8641 tagcataatg attgataatt aaaacgttta gatcgcaaaa atacgcatat caaaagcaaa
     8701 cagatgttca aaaacaacta taatacttcc aaaaatcaac ataaagtttt ctattcagaa
     8761 atttacaaca gataaatatt gaattctcta acatcatcca aagggataag aataatattt
     8821 gcaggtttct actaaaacat aaataaaaga aagagttcca ttttccgcaa aaaaagccta
     8881 tctttgttcc gttaagataa taaatcacgc ataaaactca tgccaggaga ttcattttgc
     8941 atacaatata ccaactgtac gggatgtcca aaaaatgttg agaatatcct tgtatataga
     9001 aacttaccta aaggagagca tatccccaag gataagtgta cgcagaattg tatgcttttt
     9061 atgataaagg gcgaattact tatcaatagc gaagaacatc ctggaataac gttacgcgag
     9121 aaacaaattg ttttgcaagc tattggctcc aaggtcgaaa tactggcact gacagatgtt
     9181 gaatacgttg tctactggtt caacgaactg cctttgctct gcgaagaccg atataaggaa
     9241 atgatggaac aggcggaagc tcctttgacc tacactccac tgattatgag cgaaaggctt
     9301 taccaccttg tcaccagtat gcccgaattc ctcgctgaag aaaacccttg cagcaagtat
     9361 atcgacttaa aatgcaaaga actggttttc ttgattacca acttctatcc gctgccccaa
     9421 ctgggttcat tcttctatcc gatcagcact tatacggaaa gtttccacta tttcgtcatg
     9481 cagaattaca gcaacgtgaa gaacgtggaa gaatttgcgc atctgggagg atatacgacc
     9541 actactttcc gccgactttt caaaaacctc tacggtgtgc ccgtatacga atggatactg
     9601 gaaaagaaac gggaaggaat cctggaagac ctgcagcaca ccaaaatgcg aatcactgaa
     9661 atctgtaaca gatacggatt cgactctctg tctcatttcg cacacttctg taaagactct
     9721 tttggcgata ccccacgcgc tttacgcaaa aaagcagccg gtggtgagaa aatcggaaag
     9781 gtacaataaa cagtcccatc ctactaatgt gccaatcagt tgcaccatgc gcgcatactg
     9841 gctggcatat tgacacattg gcgcattgat ccattattaa agaattattt ctttaattcc
     9901 ttgctcaatc aatctatttc ccctattttt gcagtccgta agaggtgtaa aacgtcgaaa
     9961 ttttagttct aacaattaaa taatttaaat tcaatcattt atgtggttaa gtaattcatc
    10021 tgtaggaagg aaagtggtga tgagcgttac cggtatcgcc cttgtcctgt ttctaacatt
    10081 tcacatggcg atgaacttgg ttgcaatcat ctcggctgat ggttacaaca tgatttgtga
    10141 gttcctggga gcaaactggt atgcgttagt ggctaccgca ggactagccg ctctttttgt
    10201 gattcacatc atctacgcat tctggctgac aatgcagaat cgcaaagcgc gtggtagcga
    10261 acgctatgca gtggttgaca aaccaaaaac tgtagaatgg gcatctcaaa acatgttggt
    10321 gctgggtctg atcgttatcg taggtcttgg tttgcacctc ttcaacttct gggcaaaaat
    10381 gcagttgccg gaactgatgc acaacatggg catgcacgct gatacactga cgctggctta
    10441 tgccgctaac ggtgcttatc acatccagca gactttctct agcccggttt acgtagttct
    10501 ttacctcgtt tggctgtttg ctttgtggtt ccacctgact cacggtttct ggagctctat
    10561 gcaatcactg ggatggaaca acaaagtatg gatcaatcgt tggaaatgta tttctaacat
    10621 ctattctacg attgttgtac tcggtttcgc actggtagta gtggtattct tcgtgaaaac
    10681 actgatttgt ggcggtgctt gctaaatagt aaattgtaaa tgattaaatt gtaaataata
    10741 ttatgatcaa gatagattca aaaattccag aaggcccggt ggctgagaaa tggaccaact
    10801 ataaagctca ccagaaattg gtgaaccccg ctaataaacg tcgtttggac atcatcgttg
    10861 tgggtacggg tctggcaggt gcttctgccg ctgcttcact tggtgaaatg ggtttcagag
    10921 tattcaattt ctgtattcag gattctcccc gtcgtgcaca ctctatcgct gcacagggtg
    10981 gtatcaatgc tgcaaagaat tatcaaaatg atggtgactc cgtttaccgt ctgttctacg
    11041 atactgtaaa aggtggcgac tatcgtgccc gtgaagcaaa cgtatatcgt ttggctgaag
    11101 tgtctaacgc tatcatcgac caatgtgtag cgcaaggtgt tcctttcgct cgcgaatatg
    11161 gtggtacact agataaccgt tctttcggtg gcgcacaggt atcccgtact ttctacgcta
    11221 aaggccagac tggtcagcaa ttgctgctgg gtgcttactc tgcattgagc cgtcaggtaa
    11281 acgtaggtac tgttaaactg tatacccgct atgaaatgca ggatgttgtc atcgttgacg
    11341 gacgtgcccg cggtatcatc gcaaaaaatc ttgtaacagg cgaattggaa cgtttcgctg
    11401 ctcacgctgt agtaatcgct accggtggtt atggtaacgc ttacttcctg tctactaacg
    11461 ctatgggttg taactgtaca gctgctatct cttgctaccg caagggtgct gtattcgcaa
    11521 atcctgcata cgttcagatt cacccgactt gtattccggt acatggtgac aagcagtcta
    11581 agctgacttt gatgtctgaa tctcttcgta acgacggtcg tatctgggtt ccgaagaaga
    11641 aagaagatgc tgtaaaactc cagaaaggcg aaatcaaagg aagtgatatt cctgaagaag
    11701 accgcgacta ttacttggaa cgccgctatc cggcattcgg taacctggtt ccgcgtgacg
    11761 ttgccagccg tgccgctaaa gaacgttgcg acgctggttt cggtgtaaac aacacaggtt
    11821 tggccgtatt cctcgacttc tctgaagcta tcaaccgttt gggtatcgac gttgttcttc
    11881 aacgttatgg taacctcttc gatatgtacg aagaaatcac tgacgttaat ccgggcgaac
    11941 tggctaaaga aatcagtggt gtgaaatatt ataacccgat gatgatttat ccggctatcc
    12001 actatacaat gggtggtatc tgggtagact acgaactgca aaccactatc aagggtctgt
    12061 tcgctatcgg tgaatgtaac ttctccgacc acggtgcaaa ccgcctcggt gcttctgcat
    12121 tgatgcaagg tttggctgac ggttacttcg tattgcctta cactatccag aactatctgg
    12181 cagaccagat cactgttcct cgtttctcta ccgatcttcc tgaatttgct gaagctgaaa
    12241 aagcagttca agctaagatc gacaagttca tgagcatcca gggtaaagaa tctgttgatt
    12301 ctatccacaa gaaactgggt catgtcatgt gggaatatgt aggtatggga cgtacggcag
    12361 aaggcctgaa gaaaggtatc gccgaactga aagaaatccg caaggaattc gaaacgaact
    12421 tgtttatccc cggttctaaa gaaggtatga acgtagagct tgacaaagca atccgtctgt
    12481 acgacttcat cactatgggt gagcttgttg cttacgatgc attgaaccgt aacgaaagtt
    12541 gtggtggtca cttccgtgaa gaataccaga ctgaagaagg agaagcaaaa cgtgatgacg
    12601 aaaacttctt ctatgtagca tgctgggaat atcaaggtga tgatgaaaag gctccggtat
    12661 tgcacaaaga accgctggta tatgaagcta tcaaggttca gactcgtaac tacaagagct
    12721 aatcggtgaa gttaaacatt taaaagaatt agaagaaaat ggataaaaat atatcattta
    12781 cactgaaggt atggcgccaa gctggtccga aagctaaagg tgcttttgaa acctaccaaa
    12841 tgaaagatat ccccggtgat acttccttcc tcgaaatgct ggatattctg aacgaacagc
    12901 tcatcagcga aagaaaagaa ccggtagtat tcgatcatga ctgccgcgaa ggtatctgcg
    12961 gtatgtgttc tctttacatc aacggacacc cgcacggtcc tgcaacaggt gctactactt
    13021 gccagatcta tatgcgtcgt ttcaacgacg gtgataccat cactgttgaa ccttggcgtt
    13081 cggctggttt ccctgtcatc aaagacttga tggtagaccg tactgcatac gacaagatta
    13141 tgcaagctgg tggttatgta agcgtacgca caggtgctcc gcaggatgct aacgctatct
    13201 tgatcgcgaa acctatcgct gacgaagcta tggatgctgc ttcttgtatc ggttgcggtg
    13261 cttgtgtagc tgcatgtaag aatggttctg ctatgttgtt cgtttctgca aaagtcagcc
    13321 agttgaactt gctgccgcaa ggtaaaccgg aagctttgcg ccgtgcaaaa gctatgttgt
    13381 caaagatgga tgaactggga ttcggtaact gtacaaacac tcgtgcttgt gaagctgaat
    13441 gtccgaagaa tatttctatc agcaacatcg ctcgcttgaa ccgcgatttc atcatcgcaa
    13501 aattaaaaga ctagaaattg ctagatttca atagcgagag cttaatttga ttaatgacag
    13561 aatcccctgc cggctagtcc gacaggggat ttctttatgt atgagtagag cacaattatt
    13621 attaatacgg atcagtaaca tgaactttta attcataagt ttcaccgatt tcaccttata
    13681 gccagaactg ttatgaatga gagaattacg ggtgaaagcg aggattgaaa taaggtaaaa
    13741 tcattcgtta ccgcgtaagc gtctccgcga ttctatatag tgtattaaaa taaaaaggct
    13801 aatgatccct ttttagtcat tatccttttc ccatctgtca ggaagcagtt ccctgtattt
    13861 ttcaattggt gtgttcggtt gccattcggc tgttctgttt
//
