LOCUS       c00095_gnlPro..        15316 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AAPOPFBJ_95.
ACCESSION   c00095_gnlPro..
VERSION     c00095_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:07:09
            Original ID  :: gnl|Prokka|AAPOPFBJ_95
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15316
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..849)
                     /locus_tag="ctg95_1"
                     /transl_table=11
                     /translation="MKKDEIIELLKEQIKGLRDDNNRLLDQIDALIKEVSSLKEALLQK
                     GESLSKQQRLTKGLAKLVSNTSEQQQAPQSAISEEERQKIEAEKADKRKARKNNGAKRD
                     MHYEMEEEEHVVYPDDPDFDINKARLFTTVPRICVRYECVPMRFIKHVYKIHTYTQEGR
                     LFEGKTPASAFLNSSYDGSFIAGLMELRYIQSLPVERIINYFESHGFTLKKPTAHKLIE
                     KASNLFENLYKCIRQTALSDPYKAADETYYKILVPEKNSKGKGVRKGYLWVVVGINTRM
                     IY"
     protocluster    1..15316
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2473:5316]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2474..5316
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..15316
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15316
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             complement(936..1286)
                     /locus_tag="ctg95_2"
                     /transl_table=11
                     /translation="MYSLTSANRYYLYQGFVRMNLGIDGLFKIIRSEMKDLSPVSGDIF
                     LFFGKNRQSVKILRWDGDGFLLYYKRLEGGSFELPTFNPNTGNYEISYQVLSFILNGVS
                     LKSVRLRKRFRI"
     CDS             complement(1274..1678)
                     /locus_tag="ctg95_3"
                     /transl_table=11
                     /translation="MDLAENRFGKTWKHFLEVLKVDYNCSLADVCRDQHTTFGGMSSWM
                     SRRGYSVKQAKADVVRDYYGGVEPSQPTTSSPSFTQIAPAMLSEEEFSLAGITITFNSG
                     TTISVKRATPGGVIKMLRDYERKEGDPCIL"
     CDS             2138..2419
                     /locus_tag="ctg95_4"
                     /transl_table=11
                     /translation="MEQIDNLKELINQGDVDTAIKQLDQLLQDSSVEKEKDTLYYLRGN
                     AYRKKGDWKQALDNYQYAIEINPDSPAVQARKMAIDILNFYHKDMFNQ"
     CDS             2474..2701
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_5"
                     /sec_met_domain="Fer4_7 (E-value: 1.4e-12, bitscore: 41.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.4e-09, bitscore: 30.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 4e-08, bitscore: 26.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 8.8e-08, bitscore: 25.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.5e-05, bitscore: 18.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAIVVDTERCKGCNLCVVACPLDVIALNKEVNMKGYNYAW
                     QVKEDTCNGCSSCATVCPDGCISVYKVKVE"
     CDS             2713..3795
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_6"
                     /sec_met_domain="PFOR_II (E-value: 2.3e-27, bitscore: 88.8,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.4e-49, bitscore: 162.3,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEVVLMKGNEAIAHAAIRCGADGYFGYPITPQSEVLETLAELK
                     PWETTGMVVLQAESEVAAINMVYGGAGSGKKVMTSSSSPGVSLKQEGISYLAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYKLIALAPASVQEMADFVALGFELAFK
                     YRNPAIILADGVIGQMMEKVVLPAQKPRRTEAEVIEQCPWAATGKAKDRKPNIITSLEL
                     KPEAMEINNLRFQAKYREIEENEVRFEEINCEDAEYLIIAFGSMARIGQKAMELAREKG
                     IKVGILRPITLWPFPTKAIAAYADKVKGMLVTELNAGQMIEDVRLAVNGKVKVEHFGRL
                     GGIVPDPDEIVTALKEKIIK"
     CDS             3803..3976
                     /locus_tag="ctg95_7"
                     /transl_table=11
                     /translation="MNPDKIRNVLNILFMILAVAAIITYFVAKDDFKMFIYVCGAAIFV
                     KLMEFFIRFTNR"
     CDS             3989..4753
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_8"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-25, bitscore:
                     83.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEEIIKPENLVYKKPTLMNDNAMHYCPGCSHGVVHKLIAEVIE
                     EMGMEDKTVGISPVGCAVFAYNYLDIDWQEAAHGRAPAVATAVKRLWPDRLVFTYQGDG
                     DLACIGTAETIHALNRGENITIIFINNAIYGMTGGQMAPTTLVGMKSSTCPYGRDVELH
                     GYPLKITEIAAQLEGTAYVTRQSVQSVPAIRKAKKAIRKAFENSMNGKGSNLVEIVSTC
                     SSGWKMTPEKANKWMEEHMFPFYPLGDLKDKE"
     CDS             4774..5316
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_9"
                     /sec_met_domain="POR (E-value: 9.1e-36, bitscore: 117.0,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEEIIIAGFGGQGVLSMGKILAYSGLMEGKEVTWMPAYGPEQRG
                     GTANVTVIVSDDKISSPILSKYDAAIILNQPSLEKFESKVKPGGILIYDGYGIINPPTR
                     KDIKVYRIDAMDAANEMNNAKAFNMIVLGGLLKLRPIVTLENVIKGLKKTLPERHHHLI
                     PMNEEAIKKGMELIREV"
     CDS             5425..7488
                     /locus_tag="ctg95_10"
                     /transl_table=11
                     /translation="LPPIMRRILLLYILLSVIGLTTVHAQFDNGRQRVDENGYDQYGNQ
                     VDPAMIPDRLDSANVEVQGLPPKLYMWRIKNQLGDRTIIPADTAFHHFQNSNLTEGLTG
                     HYNYLANMGSPRMSRIFFDRRDPEPTIFMEPFSSFFIRPTEFNFTNSNVPYTNLTYHKA
                     GNKVNGEERFKSYFSVNVNKKLAFGFNVDYLYGRGYYNNQNTAYFNAAVFGSYIGDKYQ
                     MQAIYSNNYLKTNENGGIEDDRYITAPEEMAQGQREYESTNIPTVLSATTNRNHDFYVF
                     LTQRYNLGFSRDIPQAENDTTPVKQEFVPVTSFIHTIQVERARHSFNSNDDMREKNYYQ
                     NTYFDTDNPNVRDSTTYVGIKNTIGIALLEGFNKYAKAGLTAFASYKISKYTLMNMEGN
                     PLPDKYNENEIFVGGELSKREGNVLHYHAIGEVGLAGKAIGQFNVKGDIDLNFPLWKDT
                     VSLIARGEVSNKLAPFYMRHYHSKHFMWDDDMDKEFRTRIEGELSIARWRTRLKAGVEN
                     IKNYTYFNQEAKPEQNSGSIQVLSASLNQDFKLGIFHLDNEVTWQKSSDQTVLPLPDLS
                     LYHNFYMQFKLAKKVLSVQLGADVRYFSKYNAPAYMPAIQNFHLQPTDDQVQIGGYPIV
                     NVYANLHLKRTRFYVMMYHVNQGMSSPNYFLSPHYPINPRVLKFGLSWNFYD"
     CDS             7506..8345
                     /locus_tag="ctg95_11"
                     /transl_table=11
                     /translation="MVSRPKLRLFRYLVPVIIVLAFIFSFRQCGKQEKPAGHPRDYAAI
                     AKEGIIRVATEYNSISFYVDSDTVSGFHYELIQAFARDKGLKTEITPIMSFEERLEGLS
                     EGRYDVIAYGILATSKLKDSLLLTSPIFLNKQVLVQRKEIGENDSLYIRTQLDLAQRTL
                     HVVKGSPSILRIQNLGNEIGDTIYIKEIDKYGSEQLISMVAHGDIDYAVCDESIALAAA
                     DSLPQIDINTAISFTQFYSWAVSKQSPVLLDSLNTWLDKFQKEKEYQKIYKKYYDKE"
     CDS             8855..9841
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg95_12"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 4.5e-26, bitscore:
                     85.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C (E-value: 1.6e-07,
                     bitscore: 24.8, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKIIKWGFIGCGEVTKTKSGPAFQKVEHSEVVAVMSRDGAKAK
                     AYAKERGIKKWYDDAQELIDDPEVNAIYIATPPSSHATYAIMSMKAGKPAYIEKPMAVT
                     YEECTRINRISNETGVPCFVAYYRRYLPYFQKVKELVENGTIGNIINVQIRFAQPPRDL
                     DYNRDNLPWRVQADIAGGGYFYDLAPHQIDLLQDMFGCILEASGYKSNRGGLYPAEDTL
                     SACFQFDSGLVGSGSWCFVAHDSAREDRIEIIGDKGMICFSVFTYEPIGLHTEKGREEI
                     CIGNPEHVQQPLIQAVVDHLLGKSVCSCDGESATLTNWVMDKILGKL"
     CDS             9997..10467
                     /locus_tag="ctg95_13"
                     /transl_table=11
                     /translation="MTREDLMRKAIELSKENVENGGGPFGAVIATKEGEIVATGVNRVT
                     ASCDPTAHAEVSAIRAAAAKLGTFNLSGYEIYTSCEPCPMCLGAIYWARLDKMYYGNNK
                     TDAKNIGFDDSFIYDELELKPEDRKLPSEILLHNEALTAFKAWAAKEDRVEY"
     CDS             10508..11317
                     /locus_tag="ctg95_14"
                     /transl_table=11
                     /translation="MKRKSLLFVMASVCLFSCQQQEELQDPSKEVIDFSTSIDQSINNA
                     LTRNSSSLTLPLKNNFAAGDVISMSVAEQDYHPFAIGMDSQTWNEAGTDSETVTFYAHY
                     PELTDEAATTRSLSSRYREIKGGLEYLFGTAQANKGSKNVALAFKRMTTPVVLLDENNQ
                     PYEGRAIVKLFLKNKGVQDLFSGKIEADPNAKPEYIDIRKVSEGILTNLIPQIIKAGEK
                     IGTVILEDGKEEPIIAEEDITIEAGTPVAVKMYARRGIIDERTPLFR"
     CDS             complement(11439..13112)
                     /locus_tag="ctg95_15"
                     /transl_table=11
                     /translation="MKKISVLIALGMLMIAPWGMAQTIYDGAKLTGKDLNGTARFVGMG
                     GAMGALGGDISTMGTNPAGIGLYRSSDVMTSFGFSLYGNESQYLGKKFNSDLTKGDFNN
                     IGFVFSSKIGNETPLRFVNFGFNYHKAKSFNNNMRMEGNLGLYSQTYLMASQAAGIEKW
                     GDSPYTDNGIGWLSILGADAGLIRDITIHDKTGGVNNIPYTYKDEQGKEVQYKDINGNP
                     LYISPGHFEGMLDNGYANFRSEERGGIDQYDFNVSFNFNDRVYLGLTLGAYSVDYNKYT
                     FYDEDYGNDEGYSLQSWNRIKGSGFDVKLGAIIRPFEYSPFRVGLAIHTPIFYSLDYKT
                     SAQVISDVMDVVTGEIKGYDVRSWDNLPGKGDMILPFDFQTPWTYNVSLGYTVGKSLAL
                     GAEYEYQDYSSMKFKDTEGNSSAYEFENSTTSMLKGVSTVRLGLEYKVIPQFAFRAGYN
                     YSTAAFHQDAFKDLAINSIQTDTDFANSKSMSNYTLGIGYRGSMFYADLAYKYSTYKEN
                     FYPFVNGFTDEDGSTIIGSPEATKVTNTRSQVLFTVGMRF"
     CDS             complement(13138..14469)
                     /locus_tag="ctg95_16"
                     /transl_table=11
                     /translation="MKKIVYFLLFALCLPIGLMAQSVDDDLYFIPSKDKQEKKETPVKK
                     ETKKQVTNIYTSPGTTVVVQDRKGRTRDVDEYNRRYDARDNEFVMDNDTLYIKEKSNPD
                     LDGEWVTGEFNGTEDDYEYAERIIRFRNPRFAISISSPLYWDVVYGPNSWDWNVYTDGM
                     YAYAFPTFSNPLWWDWRYGSYGWGWNYGWGWNRPYYAWGYSPGYWGGWYGGHWGGWYGG
                     GYWGHHHHWHGGPSWGWGGGGSGHWTGPTYTNRRSSGQSSYRNPSTVRRYGSSAVRSSG
                     SSVRGGSAVRSEGSSVRSSGSTYSRGTTSRRVVGTRTSGERSGSSSRSSATYSRPSSTR
                     SSGSSSSSRSTGSSGYSRSSGTTTRSSSARSTYSRGSSEAPRSYSPANNSNTRSSSYGT
                     SRSSSRSYSPASSGGSSSRGSYSSGGSSRSSSGGGSSRSGSARR"
ORIGIN
        1 gtatatcatc ctggtgttta tgccgacaac cacccaaagg tatcccttcc tgactccttt
       61 tcccttgctg ttcttttccg ggacgagtat tttgtaatag gtttcatcgg ctgccttata
      121 aggatcactc aaagctgtct gccggatgca cttataaaga ttttcgaaga ggtttgaggc
      181 tttctctatc aacttatgag ccgtaggttt cttcagcgta aagccatgac tctcgaagta
      241 gttgatgatt ctttcaacag gtagcgattg tatataacgt aattccatca atccggcaat
      301 aaatgaaccg tcatagctgg aattcaagaa ggccgaggcc ggtgtttttc cctcaaacag
      361 gcgaccttct tgtgtatagg tgtgtatctt gtagacatgc ttgatgaagc gcatgggtac
      421 acattcatag cggacgcata ttctgggaac agtggtaaac aaccgggcct tattgatgtc
      481 aaaatcggga tcatcgggat aaacgacatg ttcttcttcc tccatctcat aatgcatgtc
      541 acgtttggcc ccattgttct ttcttgcttt acgcttatct gctttttccg cttctatctt
      601 ctgccgctct tcttcggata tggcagattg gggagcctgt tgctgttcgg atgtgttgga
      661 tacaagtttg gcgagtccct tagtaaggcg ctgttgcttg ctaagagatt cgcctttttg
      721 aaggagtgcc tctttaaggg aagaaacctc ctttatcaaa gcatctattt ggtccaagag
      781 tctgttgttg tcatctcgta atcccttgat ttgttccttc aataactcta tgatctcatc
      841 ctttttcatg gcataaagat ataaaaaatc aacgaattag ccaaataaac cggatgatat
      901 ctttattgca aatgtctaat aatcagaatg ttgaattaga tcctaaaacg ttttctcaac
      961 cgtacagact ttaatgacac tccatttaag ataaaagaca aaacctgata agaaatctcg
     1021 taattgcctg tattggggtt aaatgtcggt aactcaaaac ttccaccttc gaggcgcttg
     1081 tagtacagaa gaaagccatc gccatcccaa cgcagtattt ttacactttg tcggttttta
     1141 ccaaagaata aaaagatatc tccggaaacg ggagacaagt ccttcatttc cgatcgtata
     1201 attttgaata aaccgtcaat gccaaggttc atacgaacaa agccctggta cagatagtat
     1261 cgattggctg atgttagaga atacatggat ctccctcctt tctttcgtaa tcgcgcaaca
     1321 ttttaatcac accaccgggt gtggcccgtt tgactgaaat ggtggttcca ctgttaaagg
     1381 tgattgtgat cccggcaaga ctaaactctt cttccgacaa catggcgggt gctatttgag
     1441 tgaatgaagg agaggaagtt gtcggttggg agggttcaac gccgccataa taatcacgga
     1501 ccacatctgc cttggcttgt ttaacgctat agccccgtct ggacatccag gaactcatac
     1561 caccaaaagt ggtatgctga tcgcggcaaa catcggctaa agaacaattg tagtctactt
     1621 tcaatacttc aaggaaatgt ttccaagttt ttccaaatcg attttctgct aaatccataa
     1681 tgcttcattt ttatacatcg caaaaatata agaatgaaaa aagggcgaca agatagaatc
     1741 gcggagacgc ttacctttca cgttttttct ttttcaaaca gtccctttca actacgctcg
     1801 ctgctacaac gagcaatgtc cgaaagcttg taactgcctg cgtcgggtgg ctgcacttct
     1861 cactaccgct gacacgtcct acatcagcat cataaaccca atgtgtattc cggccaccgg
     1921 cattgactgt ccccacttcc aaaacgcaga aaagatacat gtggcatggg gtatcagcca
     1981 cctgctggat aacgtacctt ataaggacgg aacaaactcc gcctctacta tacaatatgc
     2041 aataaactca aaacgttgca aatttccgtc ctcatttgcc ctgtttacat aaataaaaac
     2101 tatctttgcg tttcagaatc ccgaaagacg aaaagaaatg gagcaaatag acaacctaaa
     2161 agagcttatc aatcaggggg atgtggacac agcgattaag caattggacc agcttctcca
     2221 ggacagttct gtcgaaaaag agaaagatac tctttactat ttacggggaa atgcctaccg
     2281 aaagaaagga gattggaagc aggcactgga caactaccag tatgccatcg agatcaatcc
     2341 ggacagtcct gccgttcagg ccaggaagat ggcaatagat atcctcaact tctaccacaa
     2401 ggatatgttc aatcaataaa agagatgtat aatcaataac cgtactcaaa gataacgtaa
     2461 taaaataaag attatggcaa aaatcaaagg agcaatcgta gtcgacacgg agcgttgcaa
     2521 aggatgcaac ctgtgtgtag tggcgtgtcc gctcgatgta atcgccctca ataaagaggt
     2581 aaacatgaaa ggctataact atgcctggca agtgaaggaa gatacctgta acggatgcag
     2641 ctcgtgtgca acggtttgtc cggacggatg tatttcagtg tataaagtaa aagtagaata
     2701 aaagaaaaga atatggcaga agaagttgta ttaatgaaag gaaacgaagc catcgcccac
     2761 gcagctatcc gttgcggtgc cgacggttac ttcggttatc ctattactcc ccaatcggaa
     2821 gtgttggaaa cgcttgccga actgaaaccg tgggaaacaa ccggcatggt agtactccag
     2881 gcggaaagtg aagtggcagc tatcaatatg gtatatggag gtgcaggtag cggaaagaag
     2941 gtaatgacct cctcttcaag tccgggcgtg agcttgaaac aagagggaat ctcttatttg
     3001 gccggtgccg aacttccttg tctgattgtg aatgtaatgc gtggcggtcc cggattggga
     3061 actatccaac ccagccaggc tgactacttc cagacagtaa aaggtggtgg tcatggagac
     3121 tacaaactga ttgccctcgc tccggcatcc gtacaagaaa tggcggattt cgtagcatta
     3181 ggattcgaac tggccttcaa ataccgtaat ccggctatta tccttgccga cggtgtgatc
     3241 ggtcagatga tggaaaaggt tgttcttcct gcacaaaagc cacgccgcac ggaagcagaa
     3301 gtaattgaac aatgtccatg ggctgctacc ggaaaagcaa aagaccgcaa accgaatatt
     3361 atcacttccc ttgaattgaa accggaagca atggaaatca acaacctccg ttttcaagct
     3421 aaatatcgtg aaattgaaga aaatgaagta cgcttcgaag agatcaactg cgaagatgca
     3481 gagtatttga ttatcgcttt cggttcaatg gcacgtattg gccagaaagc aatggaacta
     3541 gctcgtgaaa aaggaattaa agtaggtatc cttcgcccga ttacactgtg gccgttccca
     3601 accaaagcaa ttgctgcata cgctgataaa gtaaaaggta tgctcgttac ggaactaaat
     3661 gccggacaga tgattgaaga tgtccgtctc gctgttaacg gtaaagtaaa ggtagaacat
     3721 ttcggacgtc taggtggcat cgttcccgat ccggatgaaa ttgtaactgc cttgaaagaa
     3781 aaaataatca aataacgaaa caatgaatcc cgataaaata agaaacgtac tgaacatcct
     3841 atttatgata ttggctgttg cagccatcat cacctacttt gtagcaaaag atgatttcaa
     3901 aatgtttatc tacgtatgcg gcgcggcaat ctttgtcaag ctgatggagt tttttatacg
     3961 gttcaccaac agataaggag atgaagttat gactaaagaa gaaataatca aacccgagaa
     4021 tctggtttac aaaaaaccga ctctgatgaa cgataacgcc atgcactact gcccgggttg
     4081 cagtcacggt gtggtacaca aactcattgc cgaagtcatt gaggaaatgg gtatggaaga
     4141 taaaactgta ggaatctctc cggtgggatg tgcagtgttt gcctacaact atctcgatat
     4201 tgactggcag gaagcagcac acggacgtgc tcctgctgtg gcaactgctg tgaaacgcct
     4261 gtggccggac cgccttgttt tcacttatca gggtgacggt gacttggctt gtatcggtac
     4321 agccgaaaca atccacgctt tgaaccgtgg tgagaacatc acgattatct ttatcaataa
     4381 tgcgatctac ggtatgacag gcggccagat ggctccgact acactagtag gcatgaagag
     4441 ttcgacttgt ccttacggac gtgacgttga acttcacggt tacccattga agattactga
     4501 aatcgcagcc caactggaag gaactgctta cgtaacccgt cagtccgtac aatccgtacc
     4561 ggctatccgc aaggctaaga aggcaatccg caaggctttt gagaactcca tgaacggtaa
     4621 aggttccaac ctggtagaaa tcgtttccac ttgtagttca ggctggaaga tgactccgga
     4681 gaaggcgaac aaatggatgg aagaacacat gttcccattc tatccgctgg gtgatttaaa
     4741 agataaagaa taacgctaaa agtcaacaga acaatgaaag aagaaataat tatagcagga
     4801 ttcggtggac aaggcgtatt gtctatgggt aagattctgg catattccgg tttgatggaa
     4861 ggcaaagaag tgacctggat gccggcatac ggtcccgaac aacgaggtgg aacagccaac
     4921 gttacagtta ttgtaagcga tgacaaaata tcctcaccga ttcttagtaa atacgacgct
     4981 gccatcattc tgaatcagcc ttcactcgaa aagtttgaaa gcaaagtgaa acccggcggt
     5041 atcctgattt atgacggtta cggaattatc aaccctccta cccgtaagga tattaaggta
     5101 tatcgtatcg acgcaatgga tgcagccaac gagatgaaca atgccaaagc attcaacatg
     5161 atcgtacttg gcggattatt gaagcttcgc cccatcgtaa cgttggagaa tgttatcaaa
     5221 ggattgaaga aaaccctgcc ggaacgccac catcacttga ttcctatgaa cgaggaagct
     5281 atcaagaaag ggatggagtt aatccgtgag gtttaataaa ttaaaaattg agaattgaga
     5341 attaagaaat aattgctcgc caagtaaagg atgcaacata tttttcaatt ctcaattctc
     5401 aattctcaat taaagtaagt atctttgcct ccaattatga gacgaatctt actattatat
     5461 atattacttt ccgttatagg tttgacgact gttcacgcac agttcgataa tggtcgccag
     5521 agagtagacg aaaacggata cgaccaatac ggaaatcagg tagaccctgc catgattccg
     5581 gacagattgg atagtgcaaa tgtcgaagta cagggattgc ctccaaagtt gtatatgtgg
     5641 cgtatcaaga accagttggg cgaccggact atcatcccgg cagatacagc ctttcatcat
     5701 ttccagaatt caaacctgac tgaaggactt accggacatt ataattatct ggccaatatg
     5761 ggttctcccc gtatgtcacg catcttcttt gaccgccgtg acccagagcc gactattttc
     5821 atggagcctt tctccagttt cttcattcgt cctacggaat ttaatttcac taacagtaac
     5881 gtaccttata cgaatctgac gtatcacaaa gccggtaata aagtgaatgg ggaagagcgt
     5941 ttcaaatctt acttctctgt caatgtaaac aagaaactgg ctttcggatt taatgtagac
     6001 tacctatacg gacgaggata ttacaataat cagaatacgg cgtactttaa tgcagcagtt
     6061 ttcggtagct atatcggcga caaatatcag atgcaggcta tatacagcaa taattacctg
     6121 aaaacaaatg aaaacggagg tattgaggac gaccgctata tcactgcacc ggaagaaatg
     6181 gcgcaaggtc aaagagaata tgaatcaacc aatattccta ccgtactaag tgcaacgacc
     6241 aaccgcaacc atgactttta tgtcttcctg acccaacgat ataatctcgg attcagtcgt
     6301 gacataccac aggctgaaaa tgacaccact cccgtcaaac aggagtttgt ccccgttacc
     6361 agttttatac acaccatcca agtggaacgg gcacggcata gctttaattc taatgacgac
     6421 atgcgtgaaa aaaattatta tcagaatact tactttgata cggataatcc taatgtcaga
     6481 gacagtacca cctacgtcgg aatcaaaaac accataggta ttgcgttact tgagggattc
     6541 aataaatatg ccaaagccgg attgactgca tttgcttcct ataaaatcag caagtataca
     6601 ctgatgaata tggaaggaaa tccgttgcct gataaataca acgaaaatga aatatttgtt
     6661 ggaggcgaat tatccaaacg tgaagggaat gtgcttcatt accacgctat cggtgaagtg
     6721 ggattggcag gaaaagcaat cggacaattc aatgtaaaag gagatattga cctgaacttc
     6781 ccgttgtgga aagacaccgt cagtcttata gcccgtggtg aagtcagcaa taaacttgct
     6841 cctttctata tgcgccatta tcattccaag catttcatgt gggacgacga tatggacaag
     6901 gaattccgta cccgtattga aggggaattg agcattgcac gttggaggac acgcctgaaa
     6961 gcaggagttg aaaatatcaa gaactatact tacttcaacc aggaagcaaa accggaacag
     7021 aacagcggaa gtatacaggt attatctgct agccttaatc aggacttcaa gctaggaatc
     7081 ttccatctgg acaatgaggt gacctggcag aaatccagtg accagactgt acttccttta
     7141 cctgatctct cgctatatca taacttctat atgcagttca aactggcgaa gaaagtactt
     7201 agtgtgcaat tgggagccga cgtgcgttat ttcagcaaat acaatgcacc tgcctatatg
     7261 ccggccattc agaatttcca cctgcaaccg acagacgatc aggtacagat aggaggttat
     7321 ccgattgtga atgtatatgc aaacttacat ttaaagcgta cacgtttcta tgtaatgatg
     7381 tatcacgtga accagggcat gagcagtccg aattactttc tgtctcctca ctaccccatc
     7441 aacccacgtg tgctgaaatt cggtctttca tggaatttct atgattaaca aaaactatac
     7501 gacttatggt atcacgcccc aaattgagac tgttcagata tttagtgcca gtgattattg
     7561 tattggcatt tatcttctct ttccgtcaat gcggtaagca agaaaaacct gcgggacatc
     7621 cgcgtgatta tgctgccatt gccaaggagg gtatcatacg tgtagctacc gaatataatt
     7681 ccatcagttt ttatgtagac agtgacaccg tttccggttt tcattacgaa ctgatacagg
     7741 cattcgcccg ggacaaagga ctcaaaaccg aaataacacc tattatgagt ttcgaagagc
     7801 ggttggaagg attaagcgag ggacgttatg acgtgattgc ttatggcata ttagccacca
     7861 gcaagttaaa agactctctg cttctcacct ctcccatttt cctcaacaag caagtgctgg
     7921 tgcaacgcaa agaaattgga gagaatgatt cactctatat ccgcacccaa ctggatttag
     7981 cccagcgaac acttcatgtc gtaaaaggct ccccctctat tttgcgtatt cagaatctag
     8041 gcaatgagat cggagatact atctacatca aggagattga taaatacggt tccgaacaat
     8101 tgatatcaat ggtagcgcat ggagacatcg actatgccgt ttgcgacgaa agtatcgcac
     8161 tggcggcagc agattcgttg ccgcaaatag atattaatac agccatcagc ttcacgcagt
     8221 tctactcatg ggcagtcagc aaacaatcac ccgttttact cgatagtttg aatacatggc
     8281 tggataaatt ccaaaaagag aaagaatacc agaagattta taaaaaatac tatgacaaag
     8341 aataacctca tcactttaca ggtcagaaga aaacaatcaa aaacagaatg taagatggat
     8401 atattcatgt ctatttccag aaataaactc ccaaagactt gactttcgct ttcgaatgtc
     8461 gtatctttac agagttaatg ataaagtagt ttcaattaaa ctacacgcaa aggagggaat
     8521 cgcgattctc tcctttcttt ttatccatcc gggaaaaacc tctccccgcc ccggcttttc
     8581 ttttcgctta gcctggtggt tacggttctt cagccggagg atcagcagtg ttcaccttac
     8641 ttcttaccga aatggagtat atatccgccc ccaacggacg ttctgtttgc cagaaacaga
     8701 gcctctgttc aggtaaaaca gagcctctat tgaaataaaa cgtaatgtct gttttaccac
     8761 tgtctctgct aagttaataa tcaataaagt tgctcttgac aaaaaatagc tttatctttg
     8821 gggtttgttt aagcagacac aataggtata tattatgagt gaaaagatta tcaaatgggg
     8881 cttcattggt tgtggagaag taaccaagac caaaagcggt cccgctttcc agaaagtaga
     8941 acattcggaa gtcgtagccg tgatgagtcg tgacggtgcg aaagcgaaag cgtatgccaa
     9001 agagagagga atcaaaaaat ggtatgacga tgcacaagaa ctgatcgatg atccggaagt
     9061 aaatgccatc tacattgcca ctcctccttc ctcacatgct acgtatgcca ttatgtccat
     9121 gaaagcaggc aaacctgcct atattgagaa accaatggct gtgacgtacg aagaatgcac
     9181 gcgcatcaac cgcatatcca atgaaacggg agttccctgt ttcgttgctt actatcgccg
     9241 ttatctcccc tatttccaga aagtaaagga actggtagag aacggtacta tcggtaatat
     9301 tatcaatgtg caaattcgtt ttgcccagcc gccacgcgat ctggattaca atcgtgacaa
     9361 ccttccctgg cgtgtgcagg ctgacattgc cggaggtggc tacttctacg accttgctcc
     9421 gcatcaaatt gatttgttgc aggatatgtt cggttgtatc ctcgaagcaa gcggttataa
     9481 gagcaatcgg ggtggacttt atcctgctga agatacatta agcgcctgtt tccaatttga
     9541 tagcggattg gttggtagcg gttcctggtg tttcgtagcc catgactctg cccgcgaaga
     9601 ccgtattgaa attatcggtg acaagggaat gatttgtttc tctgtcttta cttatgagcc
     9661 tatcggctta cataccgaaa aaggacggga agaaatctgt atcggtaacc cggaacatgt
     9721 gcaacaacct cttattcagg cagtggtcga tcacttgtta ggtaagtccg tttgctcctg
     9781 cgacggagaa agtgcaacgc tcactaactg ggtaatggac aagatattag gtaaactata
     9841 acccgaaaaa aagcaaaaaa aagtatcatt ttcttgcgaa gtttactgat actgttaaaa
     9901 aattaatagg aatattccat tgtatattgt tagttttttc tatctttgta aaaagaagca
     9961 aagggaaaat gaaactaaca atatattttt tgtgccatga ctagagaaga cttaatgcgg
    10021 aaagcaatcg agctctccaa agaaaatgtt gaaaatggtg gaggtccttt cggtgctgtg
    10081 attgccacga aagaggggga aatagttgca acaggagtaa atcgtgttac ggcatcttgt
    10141 gaccccactg ctcatgccga agtgagtgcg atacgtgccg cagctgccaa actcggtact
    10201 tttaatctta gcggatacga aatctatact tcctgcgaac cttgtcccat gtgtctcggt
    10261 gcgatttact gggcgcgatt ggataaaatg tactatggaa acaataagac cgatgccaag
    10321 aatattggct tcgacgactc ttttatctat gacgaactgg aactgaagcc tgaagacaga
    10381 aagcttcctt ccgaaatctt attgcataat gaagccctta ctgccttcaa agcctgggcg
    10441 gccaaagaag acagagtaga atattaaaaa acctctcact attattaacc tattaattac
    10501 ccctcaaatg aaaagaaaaa gccttttatt tgttatggca tcagtatgcc tgttcagttg
    10561 tcaacagcaa gaagaactgc aagatcccag taaagaagtg atcgactttt ctacttctat
    10621 tgaccaaagt atcaacaatg ctcttactcg taacagcagt agtttgacac ttccgttaaa
    10681 gaacaatttc gctgccggag atgtcatctc aatgtccgtt gccgagcagg attatcatcc
    10741 atttgccata ggtatggata gccagacctg gaacgaggca ggcaccgatt cggaaacggt
    10801 tactttctat gctcattatc ctgaattgac cgacgaagca gctactacca gatcattgag
    10861 cagccgctat cgtgaaatca agggtggctt agaatatttg ttcggtacag cccaagccaa
    10921 caaaggttct aagaatgttg ctcttgcatt caagagaatg acaacgcccg tcgttctgct
    10981 cgacgagaac aaccagccgt acgaaggtag agcaatcgtt aaactgttct tgaagaacaa
    11041 aggtgtacag gacttgttca gcggcaaaat cgaagctgac cccaatgcaa aaccggaata
    11101 cattgatatt cggaaagtat ctgaaggtat cttgactaac ttgattccac agatcatcaa
    11161 agccggcgag aaaataggaa cggttatcct ggaggacggt aaagaagaac ctatcatcgc
    11221 agaggaggac attaccatag aagccggaac tcctgttgcg gtaaaaatgt acgcaagacg
    11281 cggaatcatt gacgaacgaa ctccactatt cagataagac taaagaataa aaagtgatac
    11341 taataaaaat ccccggaacc gctgtagaca ctcagcattc cagggatttt ttacacacaa
    11401 aagttattat tgaaattgaa aactgtctct ttattagatt agaagcgcat acctacggta
    11461 aacaacactt gactgcgtgt attcgtaact ttcgttgctt ctggtgaacc aatgattgta
    11521 ctaccatctt catctgtaaa tccattcaca aacggataga agttttcttt atatgtagag
    11581 tatttataag ctaaatcagc ataaaacatt gatccgcgat aaccaatacc caatgtataa
    11641 ttactcattg atttagaatt ggcaaagtct gtatctgtct gaatagagtt aatagccaaa
    11701 tctttgaaag catcttgatg gaaagccgca gtactataat tatatcctgc cctaaaagca
    11761 aactgtggaa tcactttata ctccaaacca agacgaacag tactaacccc tttcaacata
    11821 gatgtcgtac tattttcaaa ttcataagca gaagaattac cttcggtatc tttaaatttc
    11881 atggaagaat aatcttgata ctcatactct gctcccaaag ccaaactctt acccaccgta
    11941 tatcctaaac ttacattata agtccaagga gtttgaaaat cgaaaggaag aatcatatcc
    12001 ccttttcccg gaagattatc ccatgatctc acgtcatatc cttttatttc tccagttaca
    12061 acatccatca catccgatat aacttgtgca ctcgttttat aatccaaact atagaatatt
    12121 ggcgtatgta tagctaatcc aactcgaaaa ggcgaatatt caaaaggacg aataatagcc
    12181 cccaacttca cgtcaaagcc agaccccttt attctattcc aactctgcaa actatatcct
    12241 tcatcgtttc cataatcctc atcataaaaa gtatacttat tataatctac agaataagca
    12301 cccagcgtca accctaaata tacccgatca ttaaaattaa acgatacatt aaaatcatat
    12361 tggtcaattc ctccgcgttc ttccgaacga aaatttgcat atccattatc taacattcct
    12421 tcaaaatgtc caggagagat ataaagagga ttaccattta tatccttata ctgtacctcc
    12481 ttcccttgtt catccttata ggtataagga atattgttta cccctcctgt tttgtcatgt
    12541 attgtaatat ctctaatcag cccagcatca gctccaagaa tagaaagcca cccaatacca
    12601 ttatccgtat aaggcgaatc tccccatttt tcaatgccag ctgcttgaga tgccattaga
    12661 taggtttggg agtaaagccc caaattacct tccatgcgca tgttgttatt aaatgatttc
    12721 gctttatgat agttaaaacc gaaattcaca aaacgcagcg gagtttcatt accaatcttc
    12781 gaagaaaaca caaacccgat gttattaaaa tctcctttag ttaaatcgga attaaacttt
    12841 ttccccaaat actgactttc attcccataa agagaaaacc caaatgaagt cattacatca
    12901 ctactacgat aaagaccaat acctgccgga ttagtcccca ttgtagatat gtctcctcca
    12961 agagctccca tagctccacc catacccaca aatcgagcag ttccatttaa atcttttcct
    13021 gttaatttgg caccatcata tatcgtttgt gccattcccc aaggcgctat catcaacatc
    13081 cctagagcaa ttaaaacact tatctttttc attcttgtaa aaccgtttaa ttaatactta
    13141 tcttctggca ctgccactac gagaggagcc tccacctgat gatgacctag aagaaccacc
    13201 actcgaataa ctgccccgag aactactacc acctgacgaa gctggagaat aactacgtga
    13261 agaagaacga gaagtaccat aggaagaaga acgggtatta ctattattcg ctggagaata
    13321 actacgcggt gcttctgaac taccacgact ataagttgat cttgcactac tgctcctagt
    13381 agtggttccg gacgaacgcg aataaccaga agaaccagtc gaacgggaag atgaagaact
    13441 tccgctactt ctagtactac ttggacgaga ataagtagca ctgctacgac tacttgagcc
    13501 actgcgttca cctgaagtcc gtgtacccac tacacgcctg gaagtagttc ccctgctata
    13561 agtagaacca gaagaacgaa cagaactacc ttctgaacga actgcagagc ctccccgaac
    13621 agaagaacca ctggaacgaa cggcactcga accataacga cgaacagtgg aaggattcct
    13681 gtaactgctt tgtccggaag aacgacggtt tgtataggta ggacctgtcc aatgaccgct
    13741 tccacctccg ccccagcccc agctaggacc accgtgccag tggtgatgat gtccccaata
    13801 gccaccgcca taccagccac cccagtggcc gccataccag ccgccccaat aacccggaga
    13861 atatccccaa gcgtagtaag gacgattcca tccccagcca tagttccatc cccagccgta
    13921 agagccataa cgccaatccc accagagtgg attactgaat gtcgggaacg cataagcata
    13981 cataccgtcg gtatatacat tccagtccca tgaattcgga ccgtaaacta catcccaata
    14041 caacgggctg ctgatgctga tagcaaaacg aggattgcgg aaacggatga tacgttcagc
    14101 gtattcatag tcgtcttccg taccattgaa ttcgcctgtc acccattctc cgtccaaatc
    14161 cggattagat ttttctttta tatataaggt atcattatcc attacgaatt cattatcacg
    14221 tgcatcgtaa cggcggttat attcatccac atcccgtgtt cttcccttac ggtcctgaac
    14281 cactactgta gtacccggtg aagtatagat gttggtcacc tgtttcttcg tttccttctt
    14341 aaccggagtt tctttcttct cctgtttgtc ttttgaagga atgaagtaaa ggtcgtcatc
    14401 aacgctttgt gccatcaagc ctatcgggag gcacaaggca aatagcaaga aataaacaat
    14461 ctttttcata tcatctcggt ttatgtaatt acttaaactt attcatgtta caaagataag
    14521 gaagagattt ttcgtccgag ggagattttc cccaaaggat aatagggaaa tccctatttc
    14581 taactatctt tgtccattat tcaccagaat taaaaacaac tatgaagtat tttgagttca
    14641 cattccgcac ccacccttgc acagaaatcg tcactgacgt actggctgcc gtactgggtg
    14701 aagtcgggtt tgaaagtttt gttgagtgtg aaggcggact gaccgcatat atccaacaga
    14761 caatctgtga tgaaaacgcc atcaagattg ccatcaccga gttcccccta cccgatacgg
    14821 atattactta tacatacacc gaagcggaag ataaggactg gaatgaagaa tgggaaaaga
    14881 atttctttca acccatcatt atcggaaacc gatgtgtgat tcacagcact ttccaccaag
    14941 atattcccaa agcggaatat gacattgtca tcaatcctca aatggccttc ggaacaggac
    15001 accacgagac taccagcctc atcattgaag aattgttgga cagcgaattg aaagataaat
    15061 ctctgctcga tatgggctgc ggaacttcaa ttcttgccat cctcgcacgt atgcggggcg
    15121 cacgcccctg tacagccatc gacattgatg aatggtgtgt acgaaactcc atcgaaaata
    15181 tcgaattgaa ccacgtagac gatattgccg tttcacaagg agatgcctcg tcgcttacag
    15241 gaaaaggacc tttcgacgtt atcatcgcca acatcaaccg gaatatatta ctgaatgata
    15301 tgaagcaata tgttgc
//
