GCA_005864055.1 - 2 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaIEPDIDCE_19 (original name was: gnl|Prokka|IEPDIDCE_19)

Region	Type	From	To	Most similar known cluster		Similarity
Region 19.1	lanthipeptide-class-iii,RRE-containing	1	30,967

gnlProkkaIEPDIDCE_93 (original name was: gnl|Prokka|IEPDIDCE_93)

Region	Type	From	To	Most similar known cluster		Similarity
Region 93.1	NRPS-like	1	5,512

No secondary metabolite regions were found in these records:: gnlProkkaIEPDIDCE_1 (original name was: gnl|Prokka|IEPDIDCE_1); gnlProkkaIEPDIDCE_2 (original name was: gnl|Prokka|IEPDIDCE_2); gnlProkkaIEPDIDCE_3 (original name was: gnl|Prokka|IEPDIDCE_3); gnlProkkaIEPDIDCE_4 (original name was: gnl|Prokka|IEPDIDCE_4); gnlProkkaIEPDIDCE_5 (original name was: gnl|Prokka|IEPDIDCE_5); gnlProkkaIEPDIDCE_6 (original name was: gnl|Prokka|IEPDIDCE_6); gnlProkkaIEPDIDCE_7 (original name was: gnl|Prokka|IEPDIDCE_7); gnlProkkaIEPDIDCE_8 (original name was: gnl|Prokka|IEPDIDCE_8); gnlProkkaIEPDIDCE_9 (original name was: gnl|Prokka|IEPDIDCE_9); gnlProkkaIEPDIDCE_10 (original name was: gnl|Prokka|IEPDIDCE_10); gnlProkkaIEPDIDCE_11 (original name was: gnl|Prokka|IEPDIDCE_11); gnlProkkaIEPDIDCE_12 (original name was: gnl|Prokka|IEPDIDCE_12); gnlProkkaIEPDIDCE_13 (original name was: gnl|Prokka|IEPDIDCE_13); gnlProkkaIEPDIDCE_14 (original name was: gnl|Prokka|IEPDIDCE_14); gnlProkkaIEPDIDCE_15 (original name was: gnl|Prokka|IEPDIDCE_15); gnlProkkaIEPDIDCE_16 (original name was: gnl|Prokka|IEPDIDCE_16); gnlProkkaIEPDIDCE_17 (original name was: gnl|Prokka|IEPDIDCE_17); gnlProkkaIEPDIDCE_18 (original name was: gnl|Prokka|IEPDIDCE_18); gnlProkkaIEPDIDCE_20 (original name was: gnl|Prokka|IEPDIDCE_20); gnlProkkaIEPDIDCE_21 (original name was: gnl|Prokka|IEPDIDCE_21); gnlProkkaIEPDIDCE_22 (original name was: gnl|Prokka|IEPDIDCE_22); gnlProkkaIEPDIDCE_23 (original name was: gnl|Prokka|IEPDIDCE_23); gnlProkkaIEPDIDCE_24 (original name was: gnl|Prokka|IEPDIDCE_24); gnlProkkaIEPDIDCE_25 (original name was: gnl|Prokka|IEPDIDCE_25); gnlProkkaIEPDIDCE_26 (original name was: gnl|Prokka|IEPDIDCE_26); gnlProkkaIEPDIDCE_27 (original name was: gnl|Prokka|IEPDIDCE_27); gnlProkkaIEPDIDCE_28 (original name was: gnl|Prokka|IEPDIDCE_28); gnlProkkaIEPDIDCE_29 (original name was: gnl|Prokka|IEPDIDCE_29); gnlProkkaIEPDIDCE_30 (original name was: gnl|Prokka|IEPDIDCE_30); gnlProkkaIEPDIDCE_31 (original name was: gnl|Prokka|IEPDIDCE_31); gnlProkkaIEPDIDCE_32 (original name was: gnl|Prokka|IEPDIDCE_32); gnlProkkaIEPDIDCE_33 (original name was: gnl|Prokka|IEPDIDCE_33); gnlProkkaIEPDIDCE_34 (original name was: gnl|Prokka|IEPDIDCE_34); gnlProkkaIEPDIDCE_35 (original name was: gnl|Prokka|IEPDIDCE_35); gnlProkkaIEPDIDCE_36 (original name was: gnl|Prokka|IEPDIDCE_36); gnlProkkaIEPDIDCE_37 (original name was: gnl|Prokka|IEPDIDCE_37); gnlProkkaIEPDIDCE_38 (original name was: gnl|Prokka|IEPDIDCE_38); gnlProkkaIEPDIDCE_39 (original name was: gnl|Prokka|IEPDIDCE_39); gnlProkkaIEPDIDCE_40 (original name was: gnl|Prokka|IEPDIDCE_40); gnlProkkaIEPDIDCE_41 (original name was: gnl|Prokka|IEPDIDCE_41); gnlProkkaIEPDIDCE_42 (original name was: gnl|Prokka|IEPDIDCE_42); gnlProkkaIEPDIDCE_43 (original name was: gnl|Prokka|IEPDIDCE_43); gnlProkkaIEPDIDCE_44 (original name was: gnl|Prokka|IEPDIDCE_44); gnlProkkaIEPDIDCE_45 (original name was: gnl|Prokka|IEPDIDCE_45); gnlProkkaIEPDIDCE_46 (original name was: gnl|Prokka|IEPDIDCE_46); gnlProkkaIEPDIDCE_47 (original name was: gnl|Prokka|IEPDIDCE_47); gnlProkkaIEPDIDCE_48 (original name was: gnl|Prokka|IEPDIDCE_48); gnlProkkaIEPDIDCE_49 (original name was: gnl|Prokka|IEPDIDCE_49); gnlProkkaIEPDIDCE_50 (original name was: gnl|Prokka|IEPDIDCE_50); gnlProkkaIEPDIDCE_51 (original name was: gnl|Prokka|IEPDIDCE_51); gnlProkkaIEPDIDCE_52 (original name was: gnl|Prokka|IEPDIDCE_52); gnlProkkaIEPDIDCE_53 (original name was: gnl|Prokka|IEPDIDCE_53); gnlProkkaIEPDIDCE_54 (original name was: gnl|Prokka|IEPDIDCE_54); gnlProkkaIEPDIDCE_55 (original name was: gnl|Prokka|IEPDIDCE_55); gnlProkkaIEPDIDCE_56 (original name was: gnl|Prokka|IEPDIDCE_56); gnlProkkaIEPDIDCE_57 (original name was: gnl|Prokka|IEPDIDCE_57); gnlProkkaIEPDIDCE_58 (original name was: gnl|Prokka|IEPDIDCE_58); gnlProkkaIEPDIDCE_59 (original name was: gnl|Prokka|IEPDIDCE_59); gnlProkkaIEPDIDCE_60 (original name was: gnl|Prokka|IEPDIDCE_60); gnlProkkaIEPDIDCE_61 (original name was: gnl|Prokka|IEPDIDCE_61); gnlProkkaIEPDIDCE_62 (original name was: gnl|Prokka|IEPDIDCE_62); gnlProkkaIEPDIDCE_63 (original name was: gnl|Prokka|IEPDIDCE_63); gnlProkkaIEPDIDCE_64 (original name was: gnl|Prokka|IEPDIDCE_64); gnlProkkaIEPDIDCE_65 (original name was: gnl|Prokka|IEPDIDCE_65); gnlProkkaIEPDIDCE_66 (original name was: gnl|Prokka|IEPDIDCE_66); gnlProkkaIEPDIDCE_67 (original name was: gnl|Prokka|IEPDIDCE_67); gnlProkkaIEPDIDCE_68 (original name was: gnl|Prokka|IEPDIDCE_68); gnlProkkaIEPDIDCE_69 (original name was: gnl|Prokka|IEPDIDCE_69); gnlProkkaIEPDIDCE_70 (original name was: gnl|Prokka|IEPDIDCE_70); gnlProkkaIEPDIDCE_71 (original name was: gnl|Prokka|IEPDIDCE_71); gnlProkkaIEPDIDCE_72 (original name was: gnl|Prokka|IEPDIDCE_72); gnlProkkaIEPDIDCE_73 (original name was: gnl|Prokka|IEPDIDCE_73); gnlProkkaIEPDIDCE_74 (original name was: gnl|Prokka|IEPDIDCE_74); gnlProkkaIEPDIDCE_75 (original name was: gnl|Prokka|IEPDIDCE_75); gnlProkkaIEPDIDCE_76 (original name was: gnl|Prokka|IEPDIDCE_76); gnlProkkaIEPDIDCE_77 (original name was: gnl|Prokka|IEPDIDCE_77); gnlProkkaIEPDIDCE_78 (original name was: gnl|Prokka|IEPDIDCE_78); gnlProkkaIEPDIDCE_79 (original name was: gnl|Prokka|IEPDIDCE_79); gnlProkkaIEPDIDCE_80 (original name was: gnl|Prokka|IEPDIDCE_80); gnlProkkaIEPDIDCE_81 (original name was: gnl|Prokka|IEPDIDCE_81); gnlProkkaIEPDIDCE_82 (original name was: gnl|Prokka|IEPDIDCE_82); gnlProkkaIEPDIDCE_83 (original name was: gnl|Prokka|IEPDIDCE_83); gnlProkkaIEPDIDCE_84 (original name was: gnl|Prokka|IEPDIDCE_84); gnlProkkaIEPDIDCE_85 (original name was: gnl|Prokka|IEPDIDCE_85); gnlProkkaIEPDIDCE_86 (original name was: gnl|Prokka|IEPDIDCE_86); gnlProkkaIEPDIDCE_87 (original name was: gnl|Prokka|IEPDIDCE_87); gnlProkkaIEPDIDCE_88 (original name was: gnl|Prokka|IEPDIDCE_88); gnlProkkaIEPDIDCE_89 (original name was: gnl|Prokka|IEPDIDCE_89); gnlProkkaIEPDIDCE_90 (original name was: gnl|Prokka|IEPDIDCE_90); gnlProkkaIEPDIDCE_91 (original name was: gnl|Prokka|IEPDIDCE_91); gnlProkkaIEPDIDCE_92 (original name was: gnl|Prokka|IEPDIDCE_92); gnlProkkaIEPDIDCE_94 (original name was: gnl|Prokka|IEPDIDCE_94); gnlProkkaIEPDIDCE_95 (original name was: gnl|Prokka|IEPDIDCE_95); gnlProkkaIEPDIDCE_96 (original name was: gnl|Prokka|IEPDIDCE_96); gnlProkkaIEPDIDCE_97 (original name was: gnl|Prokka|IEPDIDCE_97); gnlProkkaIEPDIDCE_98 (original name was: gnl|Prokka|IEPDIDCE_98); gnlProkkaIEPDIDCE_99 (original name was: gnl|Prokka|IEPDIDCE_99); gnlProkkaIEPDIDCE_100 (original name was: gnl|Prokka|IEPDIDCE_100); gnlProkkaIEPDIDCE_101 (original name was: gnl|Prokka|IEPDIDCE_101); gnlProkkaIEPDIDCE_102 (original name was: gnl|Prokka|IEPDIDCE_102); gnlProkkaIEPDIDCE_103 (original name was: gnl|Prokka|IEPDIDCE_103); gnlProkkaIEPDIDCE_104 (original name was: gnl|Prokka|IEPDIDCE_104); gnlProkkaIEPDIDCE_105 (original name was: gnl|Prokka|IEPDIDCE_105); gnlProkkaIEPDIDCE_106 (original name was: gnl|Prokka|IEPDIDCE_106); gnlProkkaIEPDIDCE_107 (original name was: gnl|Prokka|IEPDIDCE_107); gnlProkkaIEPDIDCE_108 (original name was: gnl|Prokka|IEPDIDCE_108); gnlProkkaIEPDIDCE_109 (original name was: gnl|Prokka|IEPDIDCE_109); gnlProkkaIEPDIDCE_110 (original name was: gnl|Prokka|IEPDIDCE_110); gnlProkkaIEPDIDCE_111 (original name was: gnl|Prokka|IEPDIDCE_111); gnlProkkaIEPDIDCE_112 (original name was: gnl|Prokka|IEPDIDCE_112); gnlProkkaIEPDIDCE_113 (original name was: gnl|Prokka|IEPDIDCE_113); gnlProkkaIEPDIDCE_114 (original name was: gnl|Prokka|IEPDIDCE_114); gnlProkkaIEPDIDCE_115 (original name was: gnl|Prokka|IEPDIDCE_115); gnlProkkaIEPDIDCE_116 (original name was: gnl|Prokka|IEPDIDCE_116); gnlProkkaIEPDIDCE_117 (original name was: gnl|Prokka|IEPDIDCE_117); gnlProkkaIEPDIDCE_118 (original name was: gnl|Prokka|IEPDIDCE_118); gnlProkkaIEPDIDCE_119 (original name was: gnl|Prokka|IEPDIDCE_119); gnlProkkaIEPDIDCE_120 (original name was: gnl|Prokka|IEPDIDCE_120); gnlProkkaIEPDIDCE_121 (original name was: gnl|Prokka|IEPDIDCE_121); gnlProkkaIEPDIDCE_122 (original name was: gnl|Prokka|IEPDIDCE_122); gnlProkkaIEPDIDCE_123 (original name was: gnl|Prokka|IEPDIDCE_123); gnlProkkaIEPDIDCE_124 (original name was: gnl|Prokka|IEPDIDCE_124); gnlProkkaIEPDIDCE_125 (original name was: gnl|Prokka|IEPDIDCE_125); gnlProkkaIEPDIDCE_126 (original name was: gnl|Prokka|IEPDIDCE_126); gnlProkkaIEPDIDCE_127 (original name was: gnl|Prokka|IEPDIDCE_127); gnlProkkaIEPDIDCE_128 (original name was: gnl|Prokka|IEPDIDCE_128); gnlProkkaIEPDIDCE_129 (original name was: gnl|Prokka|IEPDIDCE_129); gnlProkkaIEPDIDCE_130 (original name was: gnl|Prokka|IEPDIDCE_130); gnlProkkaIEPDIDCE_131 (original name was: gnl|Prokka|IEPDIDCE_131); gnlProkkaIEPDIDCE_132 (original name was: gnl|Prokka|IEPDIDCE_132); gnlProkkaIEPDIDCE_133 (original name was: gnl|Prokka|IEPDIDCE_133); gnlProkkaIEPDIDCE_134 (original name was: gnl|Prokka|IEPDIDCE_134); gnlProkkaIEPDIDCE_135 (original name was: gnl|Prokka|IEPDIDCE_135); gnlProkkaIEPDIDCE_136 (original name was: gnl|Prokka|IEPDIDCE_136); gnlProkkaIEPDIDCE_137 (original name was: gnl|Prokka|IEPDIDCE_137); gnlProkkaIEPDIDCE_138 (original name was: gnl|Prokka|IEPDIDCE_138); gnlProkkaIEPDIDCE_139 (original name was: gnl|Prokka|IEPDIDCE_139); gnlProkkaIEPDIDCE_140 (original name was: gnl|Prokka|IEPDIDCE_140); gnlProkkaIEPDIDCE_141 (original name was: gnl|Prokka|IEPDIDCE_141); gnlProkkaIEPDIDCE_142 (original name was: gnl|Prokka|IEPDIDCE_142); gnlProkkaIEPDIDCE_143 (original name was: gnl|Prokka|IEPDIDCE_143); gnlProkkaIEPDIDCE_144 (original name was: gnl|Prokka|IEPDIDCE_144); gnlProkkaIEPDIDCE_145 (original name was: gnl|Prokka|IEPDIDCE_145); gnlProkkaIEPDIDCE_146 (original name was: gnl|Prokka|IEPDIDCE_146); gnlProkkaIEPDIDCE_147 (original name was: gnl|Prokka|IEPDIDCE_147); gnlProkkaIEPDIDCE_148 (original name was: gnl|Prokka|IEPDIDCE_148); gnlProkkaIEPDIDCE_149 (original name was: gnl|Prokka|IEPDIDCE_149); gnlProkkaIEPDIDCE_150 (original name was: gnl|Prokka|IEPDIDCE_150); gnlProkkaIEPDIDCE_151 (original name was: gnl|Prokka|IEPDIDCE_151)

Compact view

gnlProkkaIEPDIDCE_19 - Region 1 - RRE-containing,lanthipeptide-class-iii

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Location: 1 - 30,967 nt. (total: 30,967 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-iii: (micKC and not PKS_KS)
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptide(s) for ctg19_6

ctg19_9

Leader:

MQVLDLQQLGNAGGAGLE

Core:

DSKSFSLICIGSRVGDGNHSSHKKHHKGKKH

Core with dehydrations:

DDhaKDhaFDhaLICysIGDhaRVGDGNHDhaDhaHKKHHKGKKH

antiSMASH-DB 4.0 matches for ctg19_9

100.0% NZ_CP022988.1and 2 others:

NZ_CP046131.1 Lanthipeptides: allorf_0022859_0023008_lanthipeptideNZ_KE145374.1 Lanthipeptides: allorf_617582_617731_lanthipeptide

Lanthipeptides: allorf_2143277_2143426_lanthipeptide

1

DSKSFSLICIGSRVGDGNHSSHKKHHKGKKH

31

DSKSFSLICIGSRVGDGNHSSHKKHHKGKKH

1

DSKSFSLICIGSRVGDGNHSSHKKHHKGKKH

31

48.4% NZ_SDJT01000024.1: Lanthipeptides: EST31_RS10455_lanthipeptide

2

SKSFSLICIGSRVGDGNHSS

21

SKS S ICIG GDGNHSS

1

SKSVSFICIGKITGDGNHSS

20

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg19_9 - Class III

Cleavage pHMM score: -2.40

RODEO score: 0

Monoisotopic mass: 3302.7 Da

Molecular weight: 3304.7 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 3322.7 Da N = 1; 3340.7 Da N = 2; 3358.7 Da N = 3; 3376.8 Da N = 4; 3394.8 Da N = 5

gnlProkkaIEPDIDCE_93 - Region 1 - NRPS-like

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Location: 1 - 5,512 nt. (total: 5,512 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 5512:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg93_2

AMP-binding (194..561): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: pro (Pro)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVTALAVVYK
Nearest Stachelhaus code(s):: Ala DVFSLAVVYK (65% 8Å match)
Stachelhaus code match:: 80% (moderate)