LOCUS       c00018_gnlPro..        15675 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LKOFKMPJ_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 09:14:57
            Original ID  :: gnl|Prokka|LKOFKMPJ_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15675
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15675
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2558:5675]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2559..5675
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15675
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15675
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             469..984
                     /locus_tag="ctg18_1"
                     /transl_table=11
                     /translation="MLAWLPFFLISLMFIVLLYACARSARTNIQRFKQLSLIAFLWVLT
                     AFCYTPTSYNFGTQLVIQYIQWGPVKLNVIPFQQLDIEFWLNVLLTVPLGGLLAWNFPD
                     LPWRRFIWLGFLTGLTLELGQFILDWLVNLKRWVDIDDVITNWAGVIIGAAGYKIARHV
                     PGLRWLQK"
     CDS             complement(1152..2141)
                     /locus_tag="ctg18_2"
                     /transl_table=11
                     /translation="MRMLEQIEQYIDSCIEAGDIYGASFSLITPKGINQYYHGKQGRDE
                     FAVGLDPAMIYDLASVTKVVGTTTRIFQLLSDHTIHLTDSVARFLPGFTHPEITIKNLL
                     LHNSGLPADIDNLDKMQREDLIKAVYDAPLVTAPGTTYVYSDLGFILLGWIIRAVDGSL
                     ARSIQDHVCYPLAMTNTGYNLNRPKIRFVPTEFDPRRGQIQGQVHDYKAFLLNGESGHA
                     GLFSTLTDLSVFIEMMLNFGEYQGKRVLDENVFDWLGEYDENGRTLGWERRAGRHQYFH
                     TGFTGPAVAFDLDRQIGLVVLTNRVYPTSDNQVWNQDRKRVFDLFFES"
     CDS             2559..4817
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_3"
                     /sec_met_domain="Gly_radical (E-value: 1.6e-39, bitscore:
                     126.9, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2.7e-246, bitscore:
                     810.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITSEKTTKPAAWKGFKGGHWQEEINIRDFIQNNFTQYNGDESFL
                     AGPTAATKTLNDKVLELKKQERAAGGVLDADTKVVATITSHGPGYIQKDLEKIVGLQTD
                     KPLKRAFMPFGGIRMADDALKSYGYTPDEENDKIFTEYRKTHNQGVFDVYTPDMRKARH
                     YKIITGLPDAYARGRLIPDLPRVAVYGIDRLMEDKANDFAHIGDGELTDDVIRLREEVQ
                     DQYRALADMKKMAASYGYDISKPATNAQEAIQWMYFAYLAAIKTQNGAAMSVGRIDTTM
                     DIFIQRDLDNGVLDESQAQELIDQFVMKLRMVRFIRTEEYNSLFSGDPIWATLSMCGLG
                     VDGQHHVTKTAFRILKTLDNMGAAPEPNITILWSDRLPEDFKRYATEVSIDSSTIQYEN
                     DDLMRVQWGTDYYGIACCVSAQPIADGIQYFGARANLAKAILYAINGGRDEIAGDQVGP
                     AYEPITSEYIDYDEFMKKLDKQMDWLADTYVNSLNAIHYMHDKYYYEAAQLALKNTDLD
                     RTFATGISGLSHAADSISAIKYGHVKVIRDERGIAVDFKADNDYPRYGNNDDRADDIAK
                     WLVKELYSKMNTHHLYRNAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPAY
                     GAEKSGALASLLSTAKLPYRYATDGISNTFGVTPNTLGHDLESRKDTLVNMLDGYMKND
                     GMHLNINVFNKDTLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVISRTFFESM"
     CDS             4854..5675
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74; E-value:
                     4.8e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_4"
                     /sec_met_domain="Radical_SAM (E-value: 2.6e-27, bitscore:
                     88.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKQVSTTQAAAKEPLIGYVHSIETFGSVDGPGIRYVAFLQGCH
                     MRCQYCHNPDTWKLNVGDQMTADEILEDAAKYRAFWGKTGGITVSGGESLVQIDFILDL
                     FEKAKAMNISTCLDTSGQPFTREQPFFDKFERLMKVTDISLVDIKHIDSAKHKQLTQYG
                     NENILDMIQYMAQHHDDMWIRHVLVPQRTDYDEDLKKLGDYIAKIPNDVVQKVEVLPYH
                     TLGVKKYHEMKIKYRLEGIESPTQDRVANAEKLLHTADYNGYKTWMPLPKL"
     CDS             complement(5900..6211)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FeS_assembly_P"
                     /gene_functions="other (smcogs) SMCOG1048:Iron-sulfur
                     cluster assembly protein (Score: 66.4; E-value: 6.5e-21)"
                     /gene_kind="other"
                     /locus_tag="ctg18_5"
                     /sec_met_domain="FeS_assembly_P (E-value: 7.1e-21,
                     bitscore: 66.4, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTFKDRAFEALGHVIDPELGIDLVNLGLIYDAQLTVEGTAEIT
                     MTLTIAGCPLTEWLAKDIHDELIKLPEVNNIEIEIVWEPAWNESMMSREARMELGIHS"
     CDS             7270..8190
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="LKTINLGHSNIQASSVALGIMRMDALDVAQATKVIDTAADLGINY
                     VDSADIYGGGQSSTIFGQALKQAHVSRDQLYIQSKGGIVPGKRYDFSKQHILAAVDGAL
                     QRLGVDYLDTFLLHRPDALMEPEEVAAAFDKLQTSGKVRHFGVSNFNPMQVDMLQAALN
                     QRLIINQLQFGIMHTGAIDFGLHTNMQDERSLNHDGEMIEYSRLHKMTIQAWSPYQYGN
                     FAGIFLDNPKFPELNNAMQALADEKQVTKSAIATAWILRHPAHFQVILGTMNPEHLAQN
                     AAGADVTLSRQEWYDIYFAAGNDLP"
     CDS             8360..8884
                     /locus_tag="ctg18_7"
                     /transl_table=11
                     /translation="MTSTCTICERIKLIQAHQNPYFVYELTTGYVVLADSQYFEGYTLF
                     LAKHHVTELHHLPAHEKLRYLEEMSIVQEACAQAFHADKMNIELLGNGDAHVHWHLFPR
                     HNGDTPNPGPVWWTPLETIYGDDVSLDIPRLSRLKRTLNVAIEATLNAREAELQALEAL
                     TRPASHRIDSN"
     CDS             complement(8979..9224)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GlcNAc_2-epim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_8"
                     /sec_met_domain="GlcNAc_2-epim (E-value: 0.00014, bitscore:
                     13.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAPLSSFEKNIPAVTELLAVDAELQTFFVALTPGYQREWARFI
                     FGTKAQATKERHIEVMKTVFRAGYKSKRAYDSRSDK"
     CDS             9397..9825
                     /locus_tag="ctg18_9"
                     /transl_table=11
                     /translation="MPKFDITLISPERAKAMLTEYKEQRKNSVPHLAHPGRYILPDYKL
                     TRRRAAFKIVKHTFLTPHYKSYVAMDSDNGHTLWFHNFGSLTEALFWLETGLKISDTDS
                     HSNYKEWMAKHTTEIETFKDLLREQKHKQGPKTKKKAK"
     CDS             complement(9928..10569)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_10"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 1.2e-19, bitscore:
                     63.5, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAISNGHVSFKRPAWLGDSITANNGLATVHYHDILAADWDVERSD
                     NLGISGSTIGSRYDAMAARYQAIPEDADFIAVFGGVNDYGRDQPLGQYGDCDMTTFYGA
                     LMVLLTGLQTNWPTVPKLFISAIHIGSDFGGSFSAVTNGLGYRQSDYEAAIAQMTADYG
                     VPHLSLYRDAGMTFAIPAQAAIYSVDTLHPNNAGHRVIARKLQSFLDSHF"
     CDS             complement(11586..13253)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BCCT"
                     /gene_functions="transport (smcogs)
                     SMCOG1001:betaine/carnitine/choline family transporter
                     (Score: 410.4; E-value: 2.8e-125)"
                     /gene_kind="transport"
                     /locus_tag="ctg18_11"
                     /sec_met_domain="BCCT (E-value: 3.1e-125, bitscore: 410.4,
                     seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSSRFIILKSKNIDWWVYLPTIGLFAAASVVLLMGGHSLETSLS
                     GILNWLTNNMSWLYMSVYVITFIFFIYLGFSKLGKTKLGDPDDKPEFSTYHWGSMVYAT
                     GIDASILMLSMVDPLRYLQSPSFGVKPFSTSAYNYAHMLGQFNWGPMAWMMFAPATIAI
                     AYAMYVKHIKVQRLSAAISVLQGPGKGKQIARNTIDFLVIIGIMGGVGTSVGMEIPVIS
                     KVLSAVTGIADTMTLKLGLFALLFVIFAMAVFNGLKKGIGRLSAAHVWLAIGFLIVVLI
                     VGPTLYILNSETNSIGLFVNKFITLSTNTAPNGHATAMQRQTIFYWGWWLSFMPVMGLF
                     IARISRGRTIRQVLGGMLLWGSLGCVSFYAILGGYALYLQRMGIVNLVHILNTQGQAAV
                     IAAVLSTLPLKMIMLALYCLSCFIFLATTVSSFAFITSSFTSKKLAAGEQPSRFNRMSW
                     VVIFLVFSLGLVTVGGFESIQSICAMSGFPLTIVALVLLYSIHHDLTTDPVKEAAKANA
                     KAAELARRKRLARDVEITTKTDYARERRTARKRETEAD"
ORIGIN
        1 gatgagttct aaaaagctca tttaatgttg tactaaaatt tatttgctag cgaattgact
       61 tcgcaaatgt tttgctcttg attcaaaatc aagagaccct acacatttga ttcgtcgaaa
      121 ctttgtttag ttttcaaaga tctaattccg tgtgttaatc gcttaacaca acttaatcat
      181 cataacatct taatcaatat cttgtcaaca acttttttaa gaagtaactt gattaatttg
      241 tcgtggttgc catcgcgaca acagaaacta tcttaccaat tactgaagaa gttgtcaaca
      301 actaatttca ataattattt ggtggtgaga tgtatctgcc gtagcagcaa cgtttactaa
      361 tataccaatt gaagtaaaaa gtgtcaacac tttttctgaa tttcttttta ttaatagtca
      421 aaccagcttt ctttctctat actatttaat taaaggagcg actaaattat gctagcttgg
      481 ctaccattct ttttgatttc attaatgttt attgttctac tatacgcttg tgcgcgatca
      541 gcgcgcacaa atatccagcg ttttaagcaa ctcagtttaa ttgcctttct ctgggtctta
      601 actgcttttt gctacacacc taccagttac aattttggta cccaactcgt tattcaatat
      661 attcaatggg gacccgttaa gctgaacgtg attcctttcc aacaacttga cattgaattt
      721 tggctcaacg ttctcctcac tgttccattg ggcggtttac tggcatggaa ttttcccgac
      781 ttgccttggc gtcgttttat ttggttggga tttcttacgg ggctaacact cgagctggga
      841 caattcatcc ttgactggtt ggttaacctc aaacgttggg ttgatatcga tgatgtcatc
      901 acaaattggg ctggtgtcat tatcggtgcc gctggttata aaattgcacg tcatgttccc
      961 ggacttcgct ggttgcaaaa ataacgtata tatagaagca aaaagcaaaa tagcgtttgc
     1021 ttagcaccca caagtgccaa acacttcagc ggtctagctg tcatgaaatc gtaattaaat
     1081 aagcgtcgca gccttaagtg gctgcgacgc ttatttaatt taactactaa ctattaatga
     1141 agctgccatc atcaggattc aaaaaacaga tcgaatactc gcttacgatc ttggttccag
     1201 acctgattgt cactagttgg ataaactcga tttgttaaca caaccagccc aatttgacga
     1261 tccaaatcaa aagcaactgc cgggccagta aaaccagtat ggaaatattg atgtcgtccc
     1321 gcacgtcgtt cccaacctaa cgtccggcca ttttcgtcat actcgcctaa ccagtcaaag
     1381 acattttcat ccagcacccg tttgccttga tattcaccaa agtttaacat catttcaata
     1441 aatacggata aatccgtcag cgttgagaac aagcctgcgt gaccactctc accattcaac
     1501 aaaaaggctt tataatcatg cacctgtcct tgaatctgac cccgccgcgg atcaaactcc
     1561 gtcggcacaa accgaatctt cggacgattt aagttataac ccgtattggt catcgctagt
     1621 ggatagcaaa cgtggtcttg aatactccga gccaatgagc cgtcaaccgc acgaataatc
     1681 catcccaata aaataaatcc caggtctgaa tagacatacg ttgtccctgg tgccgtgacg
     1741 agtggcgcat cataaaccgc tttgatcaga tcttcacgtt gcatcttatc caggttatca
     1801 atatctgccg gtagcccact attatgaagt aacaagtttt taatcgttat ttcaggatga
     1861 gtgaacccag gtaaaaaccg ggcaaccgag tccgttaaat gaatcgtgtg gtccgataac
     1921 aactgaaaaa tcctcgtcgt ggtccctaca accttagtta ccgatgctag gtcataaatc
     1981 atcgcaggat ctaagcccac ggcaaactca tcgcggccct gcttaccatg atagtattga
     2041 ttgatacctt taggggtgat caagctaaac gacgccccat aaatgtcgcc agcttcaata
     2101 caactgtcaa tatattgttc aatttgttcg agcatccgca ttacgcccac ctttcactac
     2161 attcactagt ttctgcttat cttctttatg ataacgaact tcctcataaa atcaacggca
     2221 aacgctttta acaccctcca cacctcgttg cactttttat taattaacta gttaaacact
     2281 tgttacatta tggacaatat tccacttata tatcaaaaca agtcttgttt ttagccgttt
     2341 tctaaatata attaagtgaa ttaccaatgc ctatctagct atgtaagtac tgttatatca
     2401 acgttaatag tcaacttttc aataatagat tgcaaaaaaa taacccaaac gtgaaataaa
     2461 tcacctgaaa gcggttacaa atccagcaaa aaatgttatg attcaaatat agaattttat
     2521 caatcatttg attggattca aattatggag gcgagaaaat gattacatca gaaaagacaa
     2581 caaaaccagc agcttggaaa ggtttcaaag gcgggcactg gcaggaagaa atcaacattc
     2641 gtgattttat tcaaaataac ttcacacagt acaatggcga cgaaagcttc ctggccggac
     2701 caacagccgc tactaagacc ttgaatgaca aagtcttaga attaaagaaa caagaacgtg
     2761 ccgctggtgg tgtgttggat gctgatacta aagtcgttgc aacgattact tcacacggcc
     2821 ctggttatat tcaaaaagat ctcgaaaaga ttgttggtct ccagactgac aagcctttga
     2881 agcgggcctt catgccattt ggtggtattc gaatggctga tgacgctttg aaatcatacg
     2941 gttatacccc tgatgaagaa aacgacaaga ttttcactga atatcgcaag actcataacc
     3001 aaggcgtctt cgatgtttat actcctgaca tgcggaaagc acgtcactac aagatcatca
     3061 ccggactacc agatgcatac gcacgtggcc gtctcattcc tgatcttcca cgggtcgctg
     3121 tttatgggat cgatcgttta atggaagaca aagctaatga ctttgcccac attggtgatg
     3181 gtgaattgac tgatgatgtt attcgcctcc gtgaagaagt tcaagatcaa taccgtgctt
     3241 tagcagatat gaagaagatg gctgccagtt atggctacga tattagcaag cctgcaacta
     3301 atgctcaaga agctattcaa tggatgtact tcgcttactt agctgctatc aagacccaaa
     3361 acggcgctgc aatgtccgtt ggccggattg atacaacgat ggacatcttc atccaacgtg
     3421 acttggacaa tggtgttctg gacgaaagcc aagctcaaga attaattgat caattcgtca
     3481 tgaaactacg gatggttcgg ttcatccgta ctgaagaata caattcgctc ttctctggtg
     3541 acccaatctg ggcaacctta tcaatgtgtg gtttaggcgt cgacggtcaa caccatgtga
     3601 ctaagaccgc tttccggatt ttaaagactt tggacaacat gggcgccgca ccagaaccaa
     3661 acatcacgat tttatggtca gaccgcttac cagaagactt caaacgttac gcaactgaag
     3721 tttcaatcga cagttcaacc attcagtatg aaaatgatga cttgatgcgg gtacaatggg
     3781 gtaccgatta ttatggcatt gcttgctgtg tttccgcaca accaattgct gatggaatcc
     3841 agtacttcgg tgcccgggca aacttagcca aagcgattct ttatgccatc aatggtggcc
     3901 gcgacgaaat tgctggagat caagttggcc ctgcttacga accaattact tcagaataca
     3961 tcgattacga cgaattcatg aagaaattag acaagcaaat ggattggtta gctgacactt
     4021 acgttaactc actgaatgca attcattata tgcatgataa gtactactat gaagctgccc
     4081 aattagcttt gaagaatact gatcttgatc ggacctttgc aactgggatt tctggcttat
     4141 cacatgccgc ggattcaatc tcagctatca agtatggtca cgttaaagta attcgtgacg
     4201 aacgtggtat cgccgttgac ttcaaagccg acaatgacta cccacgttat gggaacaatg
     4261 acgatcgcgc tgatgacatt gctaaatggt tagtcaaaga attatacagc aagatgaaca
     4321 cgcatcacct ctatcggaat gccaaacttt caacttctgt tttgacgatt acctccaacg
     4381 ttgtttatgg taagaacact ggtaccacac caaatggccg tcaaaaaggc gaaccattct
     4441 caccaggtgc taaccctgca tacggtgctg aaaagagtgg tgcattagct tcacttcttt
     4501 caactgcaaa attaccatac cgttacgcaa ctgacgggat ttccaacacg ttcggcgtta
     4561 cccctaacac gttaggccat gacctcgaat cacggaaaga cacgttagta aacatgttag
     4621 acggttacat gaagaacgat gggatgcact tgaacatcaa cgtcttcaat aaagacactt
     4681 tgattgatgc tcagaaacac cctgaagaat acccaacatt aacggttcgg gtttctggct
     4741 actgtgtcta cttcgcagat ttaaccaagg aacaacaaga tgacgttatt tcacggacat
     4801 tcttcgaatc aatgtaacat ttaatcttta atagttaaga aggcgaaagg ctcatggaaa
     4861 acaaacaagt ttcaacaacg caagcggcgg caaaggagcc tttgataggc tacgttcact
     4921 ccatcgaaac gtttggctcc gttgacggac caggtatccg ttacgtggca ttccttcaag
     4981 gatgccacat gcgttgccaa tactgtcaca accctgatac ttggaaactc aacgttggcg
     5041 atcaaatgac ggccgacgag attctcgaag acgcggctaa ataccgggct ttctggggca
     5101 agacgggtgg catcacagtc agtggtggtg aatcactggt acaaatcgac ttcatcttag
     5161 acttattcga aaaagccaag gcgatgaata tcagtacttg tctggatacc tctggacagc
     5221 cttttacccg agaacaacct ttctttgaca agttcgaacg tctaatgaag gtcacggaca
     5281 tttcgttggt cgacattaag cacatcgatt ctgccaaaca caagcagttg acccagtatg
     5341 ggaacgaaaa tatcttggat atgattcagt acatggccca acaccacgat gatatgtgga
     5401 ttcgtcacgt tctggttccc caacggactg attacgatga agacttgaag aaactcggcg
     5461 attacattgc taagattcca aacgacgtcg ttcaaaaagt cgaagtattg ccgtaccata
     5521 ctttgggcgt taaaaaatat catgaaatga agatcaagta ccggcttgaa ggaatcgagt
     5581 ctccaaccca agatcgggtg gcaaatgccg aaaagctact gcacactgct gattacaacg
     5641 ggtacaagac atggatgcca ttgccaaaac tttaaatcgg catttctagc atgactaaaa
     5701 caccagcgat acaatcgtct acagatggtt gtgtcactgg tgtttttttt gctggctcga
     5761 cgcatgcacg tattgctggc tggaattagt acagtggcac gcaaaaaagg cgcgcgagcc
     5821 taaaccagca acgtctttcc ttaatcatgc cctatccaat gaccgtcagc ccttgaacta
     5881 gctgcgaaca ggccggccac taactatgaa tgcctagttc cattcgagct tcgcgggaca
     5941 tcatactttc gttccaagca ggttcccaca caatctcaat ctcgatattg ttaacttctg
     6001 gtaatttgat cagttcatcg tgaatgtcct tagccaacca ttcggtcaaa ggacagcccg
     6061 caatggtcaa cgtcatggta atttcagcgg tcccctccac cgtcaattgt gcatcataga
     6121 tcaaccccaa gttaactaga tcaattccta attcagggtc aatgacatgt cctagcgcct
     6181 cgaaggcccg gtctttaaac gttgttgtca ttgtatctcg tccttccata ccagcttgaa
     6241 ttcactgatt aatcacgcca acgtttcgcg gtataagtgc catcacactc gatacacgtt
     6301 atcgtcatta aagcgctttc ctatctactt ctattgtacc gtatgtcagt ccatattcaa
     6361 tcaattatta gcgctaatta gccgactttt caaacgatcg gtcaatcagc aaattatgcg
     6421 actatttctc gaaaaaattt actataatcc ccgatatagc agcgttttga gtcactattg
     6481 atttttattg cgaattcgcg gttgtttttg ttgtaagcgt ttgcggttta tgctattata
     6541 ctaagtgagg aaaggaatta atcctcgatt agcaaagctt ctcaaaagag tttggctgtc
     6601 gctgtaatgt tagacagcta gtatcacagt ttgggtcgtt atcgaaaccg ttttaagcgc
     6661 cgtgaagcgt tatcggtcta gcgagtgtcg tgagatttac gttggatgac tgaacgttga
     6721 cccttagata aacgataacc gcaaagaatt aattggcatt agaatgacga acagatttta
     6781 actaagtttt agttggaaac aggtgtctcc gatgaccagt tgttagttcc acattaccag
     6841 ttccatttgt agactcaggt attacaaagt ttaaacggag gtgcatgtct gttacgaaga
     6901 cattcccaag ttttaaacgc gagtttgact ttcgttaaaa cccgtctaac gagtcgcaat
     6961 caagtaacaa ccttacttta gatcgactat agcagatagt tacaataaat acgggttagt
     7021 ccgttagaag ttggacacgc gtaaaattga atagcatgaa ggtgtatcat attaacactg
     7081 aacaattttt cattgctaat caggattatt cctcataagt agaactcaag cagagaagcc
     7141 ttgggttcta tttttttgct ctaaaatcag atttaccaac agtcggcacc aggcgtaacc
     7201 gtttacatcc tcttacgaaa accgtatact gaatttaaat caagttgcac attgaggagg
     7261 actttagttt tgaaaacgat taatttaggt cacagcaata ttcaagcttc cagcgtggcg
     7321 cttggcatca tgcgcatgga cgccttggat gtcgctcaag ccaccaaggt tatcgatacc
     7381 gctgctgatt taggcatcaa ttacgttgat tcagctgata tctacggtgg tggtcaatca
     7441 tcgaccatct tcggtcaagc actcaagcaa gctcacgtat cgcgtgatca gctctatatt
     7501 cagtcaaaag gcggcatcgt tcctggcaag cgttacgact tttccaaaca gcacatactg
     7561 gcagccgtgg atggcgcact tcaacgctta ggtgttgatt atctcgacac cttcctcctc
     7621 catcgaccgg acgccctgat ggaacccgaa gaagttgctg ccgcttttga caagttgcaa
     7681 actagcggca aggtgcgcca ctttggcgtc tctaacttca atcccatgca agttgacatg
     7741 cttcaagcgg cactaaacca acggctcatc atcaaccaac tccaatttgg tatcatgcat
     7801 accggtgcga tcgactttgg cttgcacacg aacatgcagg acgaacgtag tcttaaccac
     7861 gacggcgaga tgatcgaata ctcacggctc cataagatga cgattcaagc ttggtcgcct
     7921 tatcaatacg gtaacttcgc gggtatcttc ttagacaatc cgaagtttcc agaacttaat
     7981 aatgccatgc aagcactcgc cgatgagaaa caggtcacta aatcagctat tgcgaccgca
     8041 tggattctcc ggcacccagc ccacttccaa gtcatccttg gtacgatgaa tccggaacat
     8101 ctagctcaaa atgctgctgg agcagacgtt acgctttctc ggcaagaatg gtacgacatt
     8161 tactttgcag ctggcaacga tttaccttaa tcacgatcga cctaacagaa ttgacgatta
     8221 gtttttacaa ccaaaacgac gaccccaaat caagattgat tttcaggtcg tcgtttttta
     8281 gacgtttcac taacattttt gatgtactca ccacatctac gcgtatactt aatcctatca
     8341 agactcagga ggcgagcgaa tgacatccac ttgcacgatc tgtgaacgaa tcaaactaat
     8401 tcaggcacat cagaatcctt atttcgttta cgaactcaca acgggctacg tggtccttgc
     8461 tgatagccag tactttgaag gctacacgct ctttttagcc aaacatcacg ttaccgaatt
     8521 acatcattta ccggcacacg agaagttacg ataccttgaa gagatgagta tcgtccagga
     8581 agcttgtgcg caggcctttc atgcagacaa aatgaacatt gaactactcg ggaatggtga
     8641 cgcgcatgtt cattggcact tatttcctcg ccataacggt gatacgccca accccggtcc
     8701 cgtctggtgg acaccgctgg aaacaattta tggtgatgat gtcagtctag acattccccg
     8761 tttaagccgg ttaaagcgca cgctcaacgt agcaattgag gccacgctta atgctcggga
     8821 agcagaattg caggctttag aggcactcac aaggcctgct agccacagaa ttgacagcaa
     8881 ttagaccaaa tcaggaccca gacccgctta gatcttggtg gctacacccc aattcttaat
     8941 cgcaatccgt caccgtattt caaattgcca aaatccacct atttatccga ccgactatca
     9001 tacgctcgct tagatttata gccagctcga aaaaccgtct tcataacttc aatgtgccgt
     9061 tccttagttg cttgtgcctt agttccaaaa ataaagcggg cccattcgcg ctgataacca
     9121 ggtgtcaaag ccacaaagaa cgtttgcaat tcagcatcaa ccgctaacaa ttcggttacc
     9181 gccggaatat ttttttcaaa tgaactgagg ggtgctgtac tcataatcaa acctccgatt
     9241 agttttactt aaatttactg taagaaaggg aaaatcccta attttcaggt ttttatattt
     9301 cgaattttca taaaattgcg ctatcattat agtataagta ttattatttg actactataa
     9361 ttaaccatac tgctattcac caaggggagc cctgctatgc caaaatttga tatcaccctc
     9421 atcagtcccg aacgcgctaa agcgatgttg actgaatata aagaacaacg taagaactct
     9481 gtcccacatc tggcccatcc tggccgctat atcttgccgg attacaaatt aactcgtcgc
     9541 cgggccgcat tcaaaattgt taaacatacc tttttaacgc cccactacaa gtcttacgtt
     9601 gccatggact ctgacaacgg ccacacactc tggtttcata atttcggttc cctaaccgaa
     9661 gctttattct ggttagaaac cggccttaaa atcagcgata ccgactccca ttctaactac
     9721 aaggaatgga tggctaagca cactacggaa atcgaaacct tcaaagactt gctgcgcgag
     9781 cagaagcata aacaagggcc caagactaag aaaaaagcca agtagcccgt tttggcacct
     9841 agattcagat aagcagcagt acgcccatta gcgtgctgct gcttttattt acgatcaact
     9901 gtgccattca ttactgacta ggccaaccta aaagtggctg tccaaaaacg actgcagctt
     9961 gcgtgcaatc acgcgatgac cggcattgtt cggatgcaaa gtatccaccg aataaatggc
    10021 cgcttgagcg ggaatcgcaa acgtcattcc cgcatcacgg tacaagctca aatgtgggac
    10081 gccatagtcc gcagtcatct gggcaatcgc tgcttcataa tctgactgac gatacccgag
    10141 accattagtc accgcactaa aactgccgcc aaaatcagaa ccaatatgaa ttgctgaaat
    10201 aaataacttc ggcacggtcg gccaattcgt ctgtaatccc gtcagtaaca ccattaacgc
    10261 gccataaaat gtcgtcatat cgcaatcacc gtattgccct aacggctgat cccgaccata
    10321 gtcattgacg cccccaaaga cagcaataaa atcagcatct tcaggaatag cttgatagcg
    10381 cgccgccatc gcatcgtagc gactcccaat cgttgaacca gagattccca aattatcgct
    10441 ccgctcgaca tcccaatcag ccgccaaaat atcatgataa tgcaccgtcg ccaacccatt
    10501 attcgccgta atcgaatctc ccaaccacgc cggccgctta aaactaacgt gcccattact
    10561 aatcgccata gccaatcctc cctttactat catcgctacc attctaatcc atcccacctg
    10621 aattatggta gaaagatgtc tttatttaaa gtcaacagcc accagcttag gcccgctgga
    10681 aacagttccg gttagcgtaa acctgcttag ttcgttcgtc ctacgccgcc ctccaggcat
    10741 ttctgccaat tgctggaacg cggtggacac agatttaagc cgaagaccac gtcttaaata
    10801 ctgggcttcc actaaccaag ccaaggacgc ttgctaagtg gaatttcacc gctgagcatt
    10861 ggccgaaacg ccttccagtc gggacagtat tcgaatggcg gacgaagatg tacccaactt
    10921 ttgatgaatt tgtcattgtt ctccataaac agtaattttg ttaatcaact gttaggtcga
    10981 aaagatattg ggatagctcg ctatttcgga attactatag taataataga acacctcaac
    11041 aaagtggtta agggtaaccc taacgtctcg tttaaagttc ctgtatcaaa ataaccaacg
    11101 accaattgtg ccgagttaag tggccgttca tcagccattc gagcggcttc ctgaaacgtg
    11161 ttcggtgcca ctaaagtctg ggcttgctat gccaacggac aaatgcccaa accgcattaa
    11221 tccgttggct agacaatgct cggcttcaac ccgtggcttg agactggagg ggctgggtga
    11281 caatgctcag tagccaaatt attcttagtc ggaagtgatt tccttccggc ttagaataag
    11341 actcgtattt gagatgacgc gggttatgcg ttagctcaaa tcgatgtcgg ctgcgttcca
    11401 gcaattgtca cccagccccg gaggtcggaa taggacgctc accggctgac gaacagaaaa
    11461 ccaaccctaa aaggcatctt tctaccatta tttcaaacag gtgggccaat cttaaaaggc
    11521 tcgtattatg gaaatccata atacgagcct agtttaattg atatatttag ttcaactgag
    11581 tagcgctaat cggcttccgt ttcacgtttc cgtgcagtac gccgttcgcg tgcgtagtca
    11641 gttttagttg tgatttcaac gtcacgtgct agccgtttcc ggcgtgctaa ttcagctgct
    11701 ttggcattgg ctttcgcagc ttccttgact ggatcagtcg ttaagtcgtg atggatcgag
    11761 tacagtaaga cgagcgcgac aatcgttaat gggaagccag acatcgcaca gatggactga
    11821 atcgattcaa agccaccgac cgtgacaagc cccaatgaga agactaggaa gataacgacc
    11881 cagctcatcc gattgaaacg acttggttgt tcccccgcgg ccaacttttt actagtaaat
    11941 gacgaggtaa tgaaggcaaa tgaagatacc gtcgttgcta agaaaataaa gcaagatagg
    12001 cagtacaaag ccagcataat catcttcaat ggtaaggtcg acaatactgc tgcaatcaca
    12061 gcggcttgtc cttgcgtatt taagatgtga actaagttaa cgatgcccat ccgttgcaag
    12121 tataaggcat aaccacccaa gatggcgtag aaactgacac aacctaatga gccccatagc
    12181 aacataccac cgagcacctg acgaatcgtc cggccccgag aaatccgggc aatgaataag
    12241 cccatgactg gcataaagga taaccaccag ccccagtaga agatcgtctg ccgttgcatg
    12301 gccgttgcgt gaccatttgg tgcagtattc gtactcaacg taataaactt attgacaaac
    12361 aagccaatac tattagtttc tgagtttaaa atatacaaag ttgggccaac gattaaaaca
    12421 acgattaaga agccaatcgc taaccaaaca tgggcagcac ttagtcgacc gatccccttc
    12481 ttcaagccat tgaaaacagc catggcgaag attacgaata ataaggcaaa taaccctaac
    12541 tttaaagtca tcgtatcggc aatcccggta acggcactca aaacttttga aatgacaggg
    12601 atttccatcc cgactgaagt accaacacca cccataatcc caataataac gagaaaatca
    12661 atcgtgttcc gggcaatttg cttaccctta ccaggacctt gtagtactga aattgcggca
    12721 ctgagccgct gaaccttgat gtgtttaaca tacattgcat aggcaattgc aatcgtggct
    12781 ggcgcaaaca tcatccacgc cattggtccc caattaaatt gtcccagcat gtgcgcataa
    12841 ttatatgcag aagttgaaaa cggcttgacg ccgaatgaag ggctttggag gtaccgtaac
    12901 gggtcaacca tgctcaacat taaaatgctg gcatcgatcc cggtcgcgta aaccatactg
    12961 ccccagtgat acgttgaaaa ttctggtttg tcatcaggat caccaagttt ggttttccct
    13021 aacttactaa accctaagta aatgaaaaag ataaaagtga tcacatatac cgacatataa
    13081 agccagctca tgttatttgt gagccagttc aagatgccac ttaaactcgt ctccagcgaa
    13141 tggcccccca ttaataaaac aacggaagcc gccgcaaaga gcccaattgt tggtaaatag
    13201 acccaccaat caatattctt actttttaaa ataataaacc tgctactgag catatactct
    13261 ctatatttag atcaaattcg tggttcttcc taccagcaat ggtagtcccc acgcgtaaat
    13321 ttccgactag caatcggtac acccctccga gttaatcctc ggagcactca gcaccctgac
    13381 tgtatcaggt ttgaccggca ttgtcatccg cattctgttt gtgctaactc aaaatcagta
    13441 gcagaatttc cttctttccg ttggttgaat ccggacaacg ccatactgac aaatgatttt
    13501 taattgctta atcgacgttg gtgttcatct tgtttagcta gtgtttctat taccatcgtg
    13561 cctttagcac acgaccgtcg tcacaccacg taacgattaa tggttacact gctcttgcta
    13621 atagataacc cccttgaatc accagataag cccaccgcac aactgttaga ttaattgctt
    13681 ggtgcaccaa aaaagcgctt agtaccgggt aacaagttac cacctgcaca gcgcacgttg
    13741 gcttatacaa atgctgattt cagtattttc tgatatctga tgttcgttta taagtatact
    13801 agtattaaat cagaagtaaa atcaaccatt ttgagccgtc gaggcctaac ccgtcaagga
    13861 ttagacgagt tttacaccca tattttttct gaaacttttt aaaagttttc gtaataatta
    13921 gtttttagtt tagaatcatt cttatctgtt tcaattaaac cgatttcatg ttattcttgt
    13981 aacaagtaaa aaaacgttat catctaaaag gaggggaact gcatgcggca ctactataaa
    14041 ttaattttaa cggtcagcgt cggtatcatt gcggttattt tacagtttgg tttgcactac
    14101 caattggcag cacaaatcat cattacatta atggggtcac ttatggcctt atcaatgtta
    14161 gttgagatga tcaaaacctt acgttcaggt aagtacggag ttgatttatt agcaattacg
    14221 gcgattgtgg caacactagc tgtcggcgaa tattgggcta gccttgtcgt tctaattatg
    14281 ctcactgggg gtgactcgtt agaagattat gcggccaaaa gagcgaatac cgaattgaaa
    14341 gccttgctcg ataattcacc acgtattgcc caccgctcag tcgccggcca attaacagat
    14401 attgccgttg aagatgtcca aattggtgat cagctagtcg tcaaacctgg tgagctagtt
    14461 ccagtagacg gtcaccttat tcaaggaacg gcactctttg atgaatcttc attgacgggt
    14521 gaatctaagc cagtcgacaa gcacgttggc gatgacatta tgtctggtgc ggtcaacggc
    14581 gatagtgctg ttacaatggt tgttgataaa ttagccattg atagtcaata ccaacagtta
    14641 gtcaaattgg ttaaagaatc cgaatcacga ccagccaaat tcgtacggct ggccgatcgc
    14701 tatgcagtcc cattcacctt ggtagcatac gtcattgccg gagtagcttg ggcattcagc
    14761 ggtgatcccc accgatttgc agaagtcctc gtagtggctt caccttgccc gctgattctc
    14821 gccgcacccg ttgcactcgt ctcagggatg agccgaacta gtcggaacgg agtcgtggtc
    14881 aagactgggg acatgttgga gaagttatct acggctaagt ccgccgcgtt tgataagacg
    14941 gggaccatta ccagtggtca attaacagtc aaccaaattg ttcctcagcc tggttttact
    15001 gccgaacaaa tcttgcacct cgcagcgagc gctgaacaaa actcaagtca tatcctggcc
    15061 cgctcactcg tcaagtatgc gagtgccact agcctcagcc cggcaacaca attagcagaa
    15121 gtaacgggta atggggtcac ggcaacgatt gagcagcaac aggtcaaagt gggcaaactt
    15181 aaattcgtcg caccgactac aaccgccaag ccacttgcta ccactgctat ctacgtcggc
    15241 attgatgacc agtacgcggg ttacatcacg tttatcgaca atgtccgccc cgaagcagcc
    15301 gccacgcttc aagcactcca cgctgagggc gttcaaaacg tcatgatgct tactggtgac
    15361 caacaggcaa ttgctgatca tattgccgcc gatgtcggta tcgataccgt tgctgccgac
    15421 ctcctacccg cagataaaat tgcccactta aaggctgtac cagcgggcga acgccccgtt
    15481 atcatggttg gcgatggtgt taacgacgcg ccttccctgg ctgttgctga cgtcggcatc
    15541 gccatgggcg cccatggctc aactgctgct agtgaatcgg ccgacgtcgt catcttaaaa
    15601 gacgatctca gtcgcgtggt cacggcggtg cgcattgcta aagataccat gcaagtggct
    15661 aaacaagccg tttgg
//
