LOCUS       c00046_gnlPro..        29513 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PLMPKKEI_46.
ACCESSION   c00046_gnlPro..
VERSION     c00046_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 08:53:56
            Original ID  :: gnl|Prokka|PLMPKKEI_46
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 29513
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     cand_cluster    1..29513
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="chemical_hybrid"
                     /product="TPP_fatty_acids"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /protoclusters="3"
                     /tool="gutsmash"
     region          1..29513
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /product="TPP_AA_metabolism"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     protocluster    1..27946
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7697:17946]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7698..17946
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     protocluster    1..17637
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5112:7637]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      5113..7637
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="2"
     cand_cluster    1..17637
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="2"
                     /tool="gutsmash"
     CDS             2..193
                     /locus_tag="ctg46_1"
                     /transl_table=11
                     /translation="DPFGLNEDMKIIIFKCMDCGKEDEVPEYVVEEFHFDLKENEEVEV
                     VCPFCNGTMRRARNIPSE"
     CDS             320..2092
                     /locus_tag="ctg46_2"
                     /transl_table=11
                     /translation="MNKQLKEKLALLPDQPGCYLMKDRQQTVIYVGKAKVLKNRVRSYF
                     TGSHDAKTQRLVTEIEDFEYIVTSSNLEALILEMNLIKKHDPKYNVMLKDDKTYPFIKL
                     THERHPRLIVTRNVKKDKGRYFGPYPNVQAARETKKLLDRLYPLRKCSKLPDRVCLYYH
                     LGQCLAPCVKDISEETNRELVESITRFLRGGYNEVKKELEEKMHEAAENLEFERAKELR
                     DQIAHIESTMEKQKMTMNDLVDRDVFAYAYDKGWMCVQVFFIRQGKLIERDVSMFPLYQ
                     EADEEFLTFIGQFYSKNNHFLPKEILVPDSVDQSMIEQLLETNVHQPKKGPKKELLMLA
                     HKNAKIALKEKFSLIERDEERSIGAVQKLGEALNIYTPHRIEAFDNSNIQGTNPVSAMI
                     VFIDGKPYKKEYRKYKIKTVTGPDDYGSMREVVRRRYTRVLRENLPLPDLIIIDGGKGQ
                     INAARDVIENELGLDIPIAGLAKDEKHRTSNLLIGDPLEVVYLERNSQEFYLLQRIQDE
                     VHRFAISFHRQIRGKSAFQSVLDDIPGIGEKRKKMLLKHFGSVKKMKEASLEDIKKAGV
                     PAAAAQLLYDKLQK"
     CDS             2462..3688
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_3"
                     /sec_met_domain="AA_kinase (E-value: 4.5e-56, bitscore:
                     183.9, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLIVQKFGGTSVGSVEKIQNAANRAIAEKQKGHQVVVVVSAMGK
                     STDELVSLAKAISDQPSKREMDMLLATGEQVTISLLSMALQEKGYDAVSYTGWQAGIRT
                     EAIHGNARITDIDTSVLADQLEKGKIVIVAGFQGMTEDCEITTLGRGGSDTTAVALAAA
                     LKADKCDIYTDVPGVFTTDPRYVKSARKLEGISYDEMLELANLGAGVLHPRAVEFAKNH
                     QVPLEVRSSTETEAGTLIEEESSMEQNLIVRGIAFEDQITRVTIYGLTSGLTTLSTIFT
                     TLAKRNINVDIIIQTQAEDKTGISFSVKTEDADQTVAVLEEYKDALEFEKIETESKLAK
                     VSIVGSGMVSNPGVAAEMFAVLAQKNILIKMVSTSEIKVSTVVSENDMVKAVESLHDAF
                     ELSKHPSAV"
     CDS             complement(3732..4178)
                     /locus_tag="ctg46_4"
                     /transl_table=11
                     /translation="MKSKFEASIDNLKEIEMNAYAYELIREIVLPDMLGQDYSSMMYWA
                     GKHLARKFPLESWEEFPAFFEEAGWGTLTNVSAKKQELEFELEGPIISNRLKHQKEPCF
                     QLEAGFIAEQIQLMNDQIAESYEQVKKRADKVVLTVKWDMKDPV"
     CDS             4471..5079
                     /locus_tag="ctg46_5"
                     /transl_table=11
                     /translation="MSGNREFYFRRLHSLLGVIPVGIFLIQHLVVNQFAARGAEAFNSA
                     AHFMDSLPFRYALEIFIIFLPLIYHAVYGVYIAFTAKNNAGQYSYMRNWLFVLQRVTGI
                     ITLIFVSWHVWETRIAAQMGAEVNFDMMANILSSPAMLGFYIVGVLSTIFHFSNGLWSF
                     AVTWGITVTPRSQRISTYVTLIIFVALSYVGLKAIFAFV"
     CDS             5113..6873
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 296; E-value:
                     1.7e-90)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_6"
                     /sec_met_domain="FAD_binding_2 (E-value: 6.1e-90, bitscore:
                     296.0, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.7e-42,
                     bitscore: 138.2, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSSIIVVGGGLAGLMATIKAAESGMAVKLFSIVPVKRSHSVCA
                     QGGINGAVNTKGEGDSPWEHFDDTVYGGDFLANQPPVKAMCEAAPSIIHLLDRMGVMFN
                     RTPEGLLDFRRFGGTQHHRTAYAGATTGQQLLYALDEQVRRYEVAGLVTKYEGWEFLGA
                     VLDDDRTCRGIVAQNLTNMQIESFRSDAVIMATGGPGIIFGKSTNSMINTGSAASIVYQ
                     QGAYYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRVWTYKDGKPWYFLEEKYPAYGN
                     LVPRDIATREIFDVCVNQKLGINGENMVYLDLSHKDPKELDIKLGGIIEIYEKFMGDDP
                     RKLPMKIFPAVHYSMGGLWVDYDQMTNIPGLFAAGECDYSMHGGNRLGANSLLSAIYGG
                     MVAGPNAVKYVNGLESSAEDMSSSLFDAHVKKEEEKWADIMSMDGTENAYVLHKELGEW
                     MTANVTVVRHNDKLLKTDDKIQELMERFKKININDTTKWSNQGAMFTRQFSNMLQLARV
                     ITLGAYNRNESRGAHYKPDYPERNDDEWLKTTMAKHVSPYEAPEFEYQDVDVSLITPRK
                     RDYSKKKVAK"
     protocluster    6222..29513
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[16221:19513]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="3"
                     /tool="gutsmash"
     proto_core      16222..19513
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="3"
     CDS             6876..7637
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 96.2; E-value: 3.7e-30)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_7"
                     /sec_met_domain="Fer2_3 (E-value: 1.3e-29, bitscore: 96.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 3.6e-11, bitscore: 37.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00088, bitscore: 13.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQKTIRFIITRQDTADSTPYDEEFEIPYRPNLNVISALMEIRR
                     NPVNVKGEKTTPVTWDMNCLEEVCGACSMVINGKPRQSCTALIDQLEQPIRLKPMKTFP
                     VVRDLQVDRSRMFDSLKKVKAWIPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGVCLE
                     ACPNVNSKSKFMGPAPMSQVRLFNAHPTGAMNKSERLEALMDEGGLQDCGNSQNCVQSC
                     PKGIPLTTSIAALNRDTNLQAFRNFFGSDRV"
     CDS             7698..8141
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_8"
                     /sec_met_domain="HBT (E-value: 6.7e-14, bitscore: 45.9,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 2.5e-10, bitscore: 34.7,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPAYIDMPFQEWKTSFSFFNEVSVRFSETDMFGHMNNVTPFIY
                     FEEARISYFKKLNMMSENKQTMTVVASQQCDYLRQVMPYEELRIYVKTSAVGSSSLTLH
                     YLGENLEGEPCFTGAVVMVQVSKESGKAVSWTDEEKETLLHTR"
     CDS             8257..8481
                     /locus_tag="ctg46_9"
                     /transl_table=11
                     /translation="LKEKEFQSKPLLTKREREVFELLVQDKATKEIASELFISEKTVRN
                     HISNAMQKLGVKGRSQAVVELLRMGELEL"
     CDS             8725..9165
                     /locus_tag="ctg46_10"
                     /transl_table=11
                     /translation="MTSKPLEHVADIEKSLRHIAAIIKQKGREILNQYAITPPQFVGLQ
                     WLYELGDMTIGELSGKMYLACSTTTDLIDRMQKNELVERVKDPADRRVVRIHLLPEGER
                     IIQEVITKRQEYLRDMFESFTDEEIAIFEKSLMKLQHEMKRK"
     CDS             9173..9991
                     /locus_tag="ctg46_11"
                     /transl_table=11
                     /translation="LLEQPIGVIDSGVGGLTVAKEIMRQLPKENIIYVGDTKRCPYGPR
                     PEEEVLQYTWELTNYLLENHHIKMLVIACNTATAIALDDIQRSVGIPVVGVIQPGARAA
                     IKVTDNQHIGVIGTENTIKSNAYEEALLALNPDLKVENLACPLLVPFVESGKFLDKTAD
                     EIVKTSLYPLKDTSIDSLILGCTHYPILKEAIQRYMGEHVNIISSGDETAWEVSTILSY
                     KGLLNQSANAPDHQFLTTGARDQFAKIADDWFGHEVGHVECISLQEPIRR"
     CDS             10106..11206
                     /locus_tag="ctg46_12"
                     /transl_table=11
                     /translation="MLKKGPAVIGATCLTSALLLSGCGLFQSDKAAEEIDPPQDVTFVN
                     DEAGANSNTTAAKKTESEKSDTAKADQASSTVMRELYLIDKNGYVVAQTLPLPKSESTA
                     KQALEYLVQGGPVSEILPNGFRAVLPADTTVNVDIKKDGTAIADFSNEFKNYKKEDEQK
                     IVQSVTWTLTQFSSIDKVKLRINGHELKEMPVGGTPISDDLSRKDGINLETAGVNDLTA
                     THPLTVYYLAENEDSEYYVPVTKRIDNSEKDDITAAINELAKGPSKVSGLLTDFSEDVK
                     LVSKPKIKDGRVTLDFNQSIFGSADEKTKMISSEVLNSIVLTLTEQPEVKSVSVKVNGK
                     SELVNEKGEKLTEPVSRPSQVNTGSF"
     CDS             11317..12054
                     /locus_tag="ctg46_13"
                     /transl_table=11
                     /translation="MRHDGRQHDELRPITFDLDFISHPEGSVLITAGNTKVICNASVED
                     RVPPFLRGGGKGWITAEYSMLPRATNQRTIRESSKGKISGRTMEIQRLIGRALRAVVDL
                     EKLGERTIWIDCDVIQADGGTRTASITGAFLAMAIAIGKLIKAGTIKTNPITDFLAAIS
                     VGIDKEQGILLDLNYEEDSSAEVDMNVIMTGSGRFVELQGTGEEATFSREDLNGLLGLA
                     EKGIQELIDKQKEVLGDSLPELK"
     CDS             12076..12663
                     /locus_tag="ctg46_14"
                     /transl_table=11
                     /translation="MKEAIIATHNPGKVKEFKEILEPRGYDVKSLAEIGFTEEIEETGH
                     TFEENAILKAEAVAKAVNKMVIADDSGLSIDNLGGRPGVYSARYAGEQKDDQANIEKVL
                     SELKGIEKEQRTARFRCALAVSIPGEETKTVEGHVEGYIAEEPRGEYGFGYDPIFIVKD
                     KDKTMAELTSDEKNKISHRADALKKLSKLLEA"
     CDS             12679..13188
                     /locus_tag="ctg46_15"
                     /transl_table=11
                     /translation="MNVLIISDSHGLEEELQTIAKRHEAEVDLMIHCGDSELETRHPAL
                     EPYAVVKGNCDFAGDFKDELLLNAGSRKILVTHGHLHGIKQTLLNVYYRAEELGADIIC
                     FGHSHIAGSEVLREKLMINPGSIRLPRVRRTESYAILTLENDAATVRFYDQAGNEIEDL
                     QNRVTL"
     CDS             complement(13453..14274)
                     /locus_tag="ctg46_16"
                     /transl_table=11
                     /translation="MKSIVGVYETPQETIAAIEGLLTKGYDSDDISVVTSRRDTDYLES
                     RTGTEVNQAIDAHQDESESFFDKLKDYFTMDDTATHSKALSDLDIKTDEIDKYQEDLDD
                     GKLLVAVDTDADVIAPVDNGNALSGGFSGTNELDYTTKEEKTMPLREEQLKVDKEDVQT
                     GEVEIGKEVKTEKRDMDIPVRHDEIYVERRPVDENKTDAAPVNDSEEIRVPIVEEKLEV
                     TKKPVVTDEVVVGKRTVEENEHISETVKKEEPRLNKEGKVDGLDDDPLNNK"
     CDS             complement(14459..14914)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_17"
                     /sec_met_domain="Acetyltransf_1 (E-value: 4.9e-13,
                     bitscore: 43.2, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LHIKIDDLTGRQVVSLVNEHLHNMTLMSPPESIHALGLEKLRGPE
                     ITFWSAWEGDELAGCGALKELDTRHGEIKSMRTSASHLRKGVAKQVLQHIIEEAEKRGY
                     ERLSLETGSMASFEPARKLYESFVFQYCEPFADYDEDPNSVFMTKEL"
     CDS             complement(15072..15407)
                     /locus_tag="ctg46_18"
                     /transl_table=11
                     /translation="MNKSLADMQGFPAGFPSFPSFPQQYYPAVPSFYQQSHQPFGGYGY
                     GQPFSQAYSPLTTPSAMYSSFPYASGFYGQQFSGAGFSGHGGSLSAPAIHAGGFSGAPG
                     VHGGFRY"
     CDS             16222..17946
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_19"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-54, bitscore:
                     177.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTNVQVDSASAKCTQTMSGALMLIESLKKEKVEMIFGYPGGAVL
                     PIYDKLYNSGLVHILPRHEQGAIHAAEGYARVSGKPGVVIATSGPGATNLVTGLADAMI
                     DSLPLVVFTGQVATSVIGSDAFQEADILGITMPVTKHSYQVRQPEDLPRIIKEAFHIAT
                     TGRPGPVLIDIPKDVATIEGEFSYDHEMNLPGYQPTTEPNYLQIRKLVEAVSSAKKPVI
                     LAGAGVLHGKASEELKNYAEQQQIPVAHTLLGLGGFPADHPLFLGMAGMHGTYTANMAL
                     HECDLLISIGARFDDRVTGNLKHFARNAKIAHIDIDPAEIGKIMKTQIPVVGDSKIVLQ
                     ELIKQDGKQSDSSEWKKQLAEWKEEYPLWYVDNEEEGFKPQKLIEYIHQFTKGEAIVAT
                     DVGQHQMWSAQFYPFQKADKWVTSGGLGTMGFGLPAAIGAQLAEKDATVVAVVGDGGFQ
                     MTLQELDVIRELNLPVKVVILNNACLGMVRQWQEIFYEERYSESKFASQPDFVKLSEAY
                     GIKGIRISSEAEAKEKLEEALTSREPVVIDVRVASEEKVFPMVAPGKGLHEMVGVKP"
     CDS             17943..18461
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_20"
                     /sec_met_domain="ALS_ss_C (E-value: 3.8e-31, bitscore:
                     101.0, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKRIITLTVVNRSGVLNRITGLFTKRHYNIESITVGHTETAGVSR
                     ITFVVHVEGENDVEQLTKQLNKQIDVLKVTDITNQSIVQRELALIKVVSAPSTRTEING
                     IIEPFRASVVDVSRDSIVVQVTGESNKIEALIELLKPYGIKEIARTGTTAFARGTQQKA
                     SSNKTISIV"
     CDS             18485..19513
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_21"
                     /sec_met_domain="IlvN (E-value: 1.9e-77, bitscore: 252.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 6.8e-68, bitscore: 221.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKVYYNGDIKENVLAGKTVAVIGYGSQGHAHALNLKESGVDVIV
                     GVRQGKSFTQAQEDGHKVFSVKEAAAQAEIIMVLLPDEQQQKVYEAEIKDELTAGKSLV
                     FAHGFNVHFHQIVPPADVDVFLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVTGEARDK
                     ALAYAKGIGGARAGVLETTFKEETETDLFGEQAVLCGGLSALVKAGFETLTEAGYQPEL
                     AYFECLHELKLIVDLMYEEGLAGMRYSISDTAQWGDFVSGPRVVDAKVKESMKEVLKDI
                     QNGTFAKEWIVENQVNRPRFNAINASENEHQIEVVGRKLREMMPFVKQGKKKEAVVSVA
                     QN"
     CDS             19500..21056
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_22"
                     /sec_met_domain="HMGL-like (E-value: 7.2e-99, bitscore:
                     324.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRKINFFDTTLRDGEQSPGVNLNTQEKLAIAKQLERLGADIIEAG
                     FPASSRGDFLAVQEIARTIKNCSVTGLARCVKGDIDAAWEALKEGAHPRIHVFIATSDI
                     HLKHKLKMTREQVIERAVEMVTYAKERFPIVQWSAEDACRTELPFLAEIVEKVIDAGAS
                     VINLPDTVGYLAPAEYGNIFKYMKENVPNIHKAKLSAHCHDDLGMAVANSLAAIENGAD
                     QIECAVNGIGERAGNAALEEIAVALHTRKDFYQVETGITLNEIKRTSDLVSKLTGMAVP
                     RNKAVVGDNAFAHESGIHQDGFLKEKSTYEIISPELVGVTADALVLGKHSGRHAFKDRL
                     TALGFQFDSEEINKFFMMFKELTEKKKEITDEDLVSLILEEKVTDRKIGYEFLSLQVHY
                     GTSQVPTATLSLKNQENAELIQEAATGAGSVEAIYNTLERCIDKDVELLDYRIQSNRKG
                     EDAFAQVYVRVLVNGKESAGRGIAQDVLEASAKAYLNAVNRQLVFQSNMSGLKNHTAVG
                     S"
     CDS             21077..22174
                     /locus_tag="ctg46_23"
                     /transl_table=11
                     /translation="LKKRIALLPGDGIGPEVLESATDVLKSVAERFNHEFEFEYGLIGG
                     AAIDEHHNPLPEETVAACKNADAILLGAVGGPKWDQNPSELRPEKGLLSIRKQLDLFAN
                     LRPVKVFESLSDASPLKKEYIDNVDFVIVRELTGGLYFGQPSKRYVNTEGEQEAVDTLF
                     YKRTEIERVIREGFKMAAARKGKVTSVDKANVLESSRLWREVAEDVAQEFPDVKLEHML
                     VDNAAMQLIYAPNQFDVVVTENMFGDILSDEASMLTGSLGMLPSASLSSSGLHLFEPVH
                     GSAPDIAGKGMANPFAAILSAAMLLRTSFGLEEEAKAVEDAVNKVLASGKRTRDLARGE
                     EFSSTQAITEEVKAAIMSENTISNV"
     CDS             22224..23642
                     /locus_tag="ctg46_24"
                     /transl_table=11
                     /translation="MMPRTIIEKIWDQHIVKHGEGKPDLLYIDLHLIHEVTSPQAFEGL
                     RQKGRKVRRPQNTFATMDHNIPTVNRFEIKDEVAKRQVTALERNCEEFGVRLADLHSVD
                     QGIVHVVGPELGLTLPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLSTQTLWQQRP
                     KTLEVRVDGTLQKGVTAKDVILAVIGKYGVKFGTGYVIEYTGEVFRNMTMDERMTVCNM
                     SIEAGARAGLIAPDEVTFEYCKNRKYTPKGEEFAKAVEEWKALRTDPGAVYDKSIVLDG
                     NKISPMVTWGINPGMVLPVDSEVPAPESFSAEDDKKEAIRAYEYMGLTPHQKIEDIKVE
                     HVFIGSCTNSRMTDLRQAANMIKGKKVADSVRAIVVPGSQSVKLQAEKEGLDQIFLEAG
                     FEWRESGCSMCLSMNNDVVPEGERCASTSNRNFEGRQGKGARTHLVSPAMAAMAAIHGH
                     FVDVRKFYQEKTVV"
     CDS             23655..24254
                     /locus_tag="ctg46_25"
                     /transl_table=11
                     /translation="MEPLKSHTGKAAVLNRINVDTDQIIPKQFLKRIERTGYGRFAFFD
                     WRYDANGEPNPEFELNQPVYQGASILIAGENFGCGSSREHAPWALDDYGFKIIIAPSFA
                     DIFHQNCFKNGMLPIRMPYDNWKQLVGQYENQSLQMTVDLENQLIHDSEGNQISFEVDP
                     HWKEMLINGYDEISLTLLLEDEIKQFESQRSSWLQA"
     CDS             24373..25377
                     /locus_tag="ctg46_26"
                     /transl_table=11
                     /translation="MTHDKKNAKIIPFPHLKDRLVEKGMSSLKEKKYQEALELFSEAMK
                     YDDTESDLHLGMAICFLELGELEEAKSVCEKMLKEGYGHYFTVLQVYMTILIQLKKYEE
                     VKSTIEAVLEENQLPAESAEQFYKLLDFSRKMTDPDREDEAWAEEYEDTIDTEKVLASP
                     EEQMNLIHSLKDRNVAKYTGLLKTILQDPSAHPIIKTMIVMLLAEHEYSKPVHISKFGE
                     SLTIEPSEIVPPDAAPILHRVLRVLDETLGNENPTLYAAVEELWRRHLYVLYPFQPKLL
                     SADLWAAALHKVGYEMHGIEIESEELHMMYEFTDRELDEACTMLKDIEEISYL"
     CDS             25605..26879
                     /locus_tag="ctg46_27"
                     /transl_table=11
                     /translation="MSVKWEKQEGNEGVLTVEVDAETFKTALDDAFKKVVKQVSIPGFR
                     KGKIPRGLFEQRFGVEALYQDALDILLPVEYPKAVEEAGIEPVDRPEIDVEKIEKGESL
                     IFTAKVTVKPEVKLGEYKGLGIEKDDTTVTDEDVQNELKALQERQAELVVKEEGAVEEG
                     NTVVLDFEGFVDGEAFEGGKAENYSLEVGSGSFIPGFEDQLVGLEAGAEKDVEVTFPEE
                     YHAEDLAGKPAVFKVKIHEIKAKELPELDDEFAKDIDEEVETLAELTEKTKKRLEEAKE
                     NEADAKLREELVLKASENAEIDVPQAMVDTELDRMLKEFEQRLQMQGMNLELYTQFSGQ
                     DEAALKEQMKEDAEKRVKSNLTLEAIAKAENLEVSDEEVDAELTKMAEAYNMPVENIKQ
                     AIGSTDAMKEDLKVRKAIDFLVENR"
     CDS             27151..28413
                     /locus_tag="ctg46_28"
                     /transl_table=11
                     /translation="MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEI
                     VEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDD
                     VELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLI
                     QAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQ
                     GGRKHPHQEFIQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLL
                     SKVLPEDLLRFGLIPEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNV
                     ELEFEEEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTH
                     GEPPRLLLKDGTEVSQDKTSA"
ORIGIN
        1 agatccattt ggattaaatg aggatatgaa aataattatt tttaaatgca tggattgtgg
       61 aaaagaagat gaggttccag aatatgtggt tgaagagttc cattttgatt taaaggaaaa
      121 tgaagaagta gaagtagtct gtcctttttg taacggaaca atgagacgag cgagaaatat
      181 cccaagtgaa taatcttcac ttgggacgtg atttaagtcg cgttagcgat tttgttcttc
      241 gccaattgtg aaccatagag aaaaacaaac gttcgtgtta aactggaaat aaaggattaa
      301 acataaggaa gggtaacata tgaacaaaca actgaaagaa aaactcgccc tccttcctga
      361 tcaaccgggt tgttatctca tgaaggaccg gcagcagact gtgatctacg tagggaaagc
      421 aaaagtgctg aaaaacagag tgcgctccta cttcaccggt tctcacgacg cgaaaaccca
      481 aaggcttgtg acggaaatcg aggattttga atatatcgtg acgtcctcca atcttgaagc
      541 gcttatttta gaaatgaatc tgatcaaaaa gcatgatccg aaatacaacg tcatgctcaa
      601 agacgacaaa acctatcctt tcataaaact cacccatgaa cgccacccaa ggctgattgt
      661 cacccgcaat gtcaaaaaag acaaagggcg ctatttcggg ccgtatccga atgtacaggc
      721 agcaagggaa acaaaaaaac tgctcgaccg tctgtatcct ctcagaaaat gctccaagct
      781 cccggacaga gtgtgccttt actatcatct gggccaatgc ctcgctccgt gcgtaaagga
      841 tatttccgaa gagacgaaca gagagctggt tgaaagcatt acacgtttct taaggggcgg
      901 ctataatgag gtcaaaaaag agcttgaaga gaaaatgcat gaagctgctg agaatcttga
      961 gtttgaacga gcaaaagagc ttcgtgacca aattgcccat attgaatcaa cgatggaaaa
     1021 acaaaaaatg acgatgaacg atctagtcga ccgtgatgta ttcgcgtatg cgtacgataa
     1081 gggctggatg tgcgtgcagg tctttttcat ccgccaagga aagctcattg aacgcgatgt
     1141 cagcatgttc ccgctttatc aggaagcaga tgaagagttc ctcacgttca tcgggcagtt
     1201 ctattcaaaa aacaaccact tccttccgaa ggagatttta gttccggaca gcgtagatca
     1261 atctatgatc gagcagctgc tggaaacaaa cgttcaccag ccgaaaaaag gcccgaaaaa
     1321 agaactgctc atgcttgccc ataaaaatgc gaaaatcgca ttgaaagaaa aattctcttt
     1381 aatcgaacgg gacgaggagc gttcaatcgg ggctgtgcag aaactaggtg aggcattaaa
     1441 tatttatacg ccgcacagaa ttgaagcgtt tgataactca aacatacagg ggacaaaccc
     1501 ggtttccgcg atgattgtgt ttatcgatgg caaaccatac aaaaaggaat accgcaaata
     1561 taaaatcaaa accgttacag ggccggatga ttacggttct atgagagagg ttgtcagaag
     1621 acgctatacg agagtgcttc gtgagaatct gccgctgccc gatctgatta tcattgacgg
     1681 aggaaaaggg cagatcaacg cagcaaggga tgttattgaa aatgaactcg gcttggatat
     1741 cccgatcgcc ggtttagcga aagatgaaaa acacagaacc tcaaatttac tgatcggtga
     1801 tccgctggag gtggtgtatc tggaacgaaa cagccaggaa ttttacctcc tgcagcgcat
     1861 tcaggacgag gtgcaccgtt ttgcaatcag ttttcacagg caaatccgcg gaaaaagcgc
     1921 gtttcaatcc gttttggacg acatcccggg tatcggagag aaaagaaaga aaatgctgtt
     1981 aaagcatttc ggttccgtta aaaaaatgaa ggaagcaagc cttgaggaca tcaaaaaagc
     2041 cggtgttccc gcagcggcgg ctcagctcct ttacgacaaa ttgcaaaaat aatgttgtcc
     2101 ttttaaataa gatctgataa aatgtgaact aatttcatag ttagatcgtg ttatatggtg
     2161 aagatagagg tgcgaacttc aagagtatgc ctttggagaa agatggattc tgtgaaaaag
     2221 gctgaaaggg gagcgtcgcc gaagcaagta aaaccccatc ggtattattt gctggccgtg
     2281 cattgaataa atgtaaggct gtcaagaaat cattttcttg gagggctatc tcgttgttca
     2341 taatcattta tgatgattaa ttgataagca atgagagtat tcctctcatt gcttttttta
     2401 ttgtggacaa agcgctcttt ctcctcaccc gcacgaacca aaatgtaaag ggtggtaata
     2461 catgggtctt attgtacaaa aattcggagg cacttccgtc ggctcagtcg aaaaaattca
     2521 aaatgcggca aaccgcgcaa ttgcagaaaa acagaaaggc catcaagtcg ttgtcgtcgt
     2581 ttcagcaatg ggaaaatcca ctgacgaatt ggtcagcctt gcaaaagcta tttctgacca
     2641 gccgagcaaa cgcgaaatgg atatgctgct ggcgacaggc gagcaggtca cgatttcact
     2701 cctttcaatg gcattgcagg aaaaaggcta tgatgctgtg tcttatactg gctggcaggc
     2761 gggaatccgt acggaggcca ttcacggaaa cgccagaatt acagatatcg acacttcggt
     2821 tttagcagac cagcttgaaa aaggaaaaat tgtcattgtt gcaggattcc aaggcatgac
     2881 agaggattgt gaaattacga cattgggccg gggcggttca gatacaacag cagttgcttt
     2941 ggctgccgct ttaaaagctg ataaatgtga catatacaca gacgtgccag gcgtgtttac
     3001 aaccgatccg cgctatgtga aatcagcgag aaaacttgag ggcatctcat acgatgaaat
     3061 gcttgagctt gccaatttag gcgccggtgt tcttcatccg agagcagttg agttcgcgaa
     3121 aaatcaccaa gtgccgttag aagtgcgttc aagtacagaa accgaagcgg gaacattaat
     3181 tgaggaggaa tcatccatgg aacagaattt aattgtcaga ggcattgcat ttgaagatca
     3241 aatcacaaga gtaaccattt acgggctgac tagcggcctg acaactttgt ctactatttt
     3301 tacaacactt gccaaaagaa acataaacgt ggatatcatt atccaaacgc aggccgagga
     3361 caagactgga atttccttct ctgtcaaaac agaagatgca gaccaaaccg ttgcggtgct
     3421 tgaagagtat aaagacgcgc tggaatttga gaaaatcgag acagaaagca aattggctaa
     3481 agtatctatt gttggatccg gcatggtctc aaatcccggt gtagcggctg aaatgtttgc
     3541 tgtactggcg caaaaaaaca ttttaatcaa aatggtcagc acatctgaaa tcaaagtgtc
     3601 aacagtcgta agcgaaaatg acatggtgaa agcagtcgag tcgcttcacg atgcatttga
     3661 gctttcaaaa cacccttcag ctgtgtaatg acaatcaaaa aggcgggact atgcagtcac
     3721 cgcctttttg attacactgg gtctttcata tcccatttca cagtcagaac cactttatcg
     3781 gctctctttt tcacttgttc atatgattcg gcaatctgat cattcatcaa ttgaatttgt
     3841 tcagcgataa aaccagcctc cagctgaaag caaggttctt tctgatgttt aagccggttg
     3901 gaaatgatcg gcccttcaag ttcaaattca agctcctgtt ttttagcgct tacgttggtg
     3961 agtgttcccc agcccgcttc ttcaaagaag gccggaaatt cctcccatga ttcaagagga
     4021 aacttacggg cgagatgttt tcctgcccaa tacatcatgg aagagtaatc ttggccaagc
     4081 atatctggga gaacgatctc tcgtattagt tcgtaggcat aggcgttcat ttcaatttct
     4141 tttaggttgt caatagatgc ttcaaattta gacttcatat ctgtctcccc tctctcctgc
     4201 gtatattata gcttaaacag gggggaggat tacagaatga tcctgtaatt cttatgaaaa
     4261 attaagcaag aaatatatat tgataaaata aaatttttca atcaactaat caattcggaa
     4321 aattataatt tatgtacgcg ttttcttgac gcccttttga gggaggagta aaatgaaatt
     4381 gtcaataaat cttaataaag tgcttacaat tgaaagaagt gggggaagag atttagcaca
     4441 tttcgcactt atcaaacagg gggtaaagta atgtctggga acagagagtt ttattttcga
     4501 agattgcatt ccttgcttgg cgtcataccg gtcggcatct ttcttattca gcatttagtc
     4561 gtcaaccagt ttgccgcaag gggcgctgaa gcattcaata gcgctgctca ttttatggat
     4621 agtctgcctt tcaggtatgc cttggaaatt tttattatct tcttaccatt aatttatcat
     4681 gcagtttatg gtgtgtacat agcgtttact gcgaaaaata acgcaggcca atacagctac
     4741 atgagaaact ggctattcgt cctgcagcgt gtaaccggta tcatcaccct catttttgtc
     4801 agctggcacg tgtgggaaac ccgcattgcc gcacaaatgg gcgctgaggt caatttcgac
     4861 atgatggcga atattttgag ctctccggct atgcttggtt tttacattgt cggtgtttta
     4921 tcaacaattt tccacttctc gaacggttta tggtctttcg ctgttacttg gggcatcacg
     4981 gtaacgcctc gttctcaaag aatttcgaca tacgttacgc tgattatttt tgttgcactg
     5041 tcatacgtag gcttaaaagc gatttttgca tttgtttaag ggtactagat tactagaggg
     5101 agaggggcta tcatgagtca atcaagcatt atcgtagtcg gcgggggtct tgccggcctc
     5161 atggcgacaa ttaaagcagc ggaatcagga atggcggtta aattgttttc catcgttcct
     5221 gtcaaacgtt ctcattcagt ttgtgcgcaa ggcggcataa acggagcggt caatacaaaa
     5281 ggggaaggtg actctccgtg ggaacatttt gatgacacgg tatacggggg agactttctt
     5341 gccaaccagc cgccggtcaa ggcgatgtgt gaagcggcgc cttcgatcat ccacttatta
     5401 gaccggatgg gcgtcatgtt taaccggacg cctgaaggtc tgcttgattt ccgccgattc
     5461 gggggtacac agcaccacag aactgcttat gctggtgcga cgacgggaca gcagctgctt
     5521 tacgcactgg acgagcaagt gcgcagatac gaagttgcgg gtctggtcac aaaatacgaa
     5581 ggctgggaat tccttggcgc tgttttagat gatgacagaa cctgccgtgg aattgttgca
     5641 caaaacctga caaacatgca aattgaatcc ttccgttcag acgctgtcat tatggcgacg
     5701 ggcggaccgg gaatcatctt tggaaaatca acgaactcca tgattaatac aggatctgct
     5761 gcgtcaatcg tttatcagca gggagcgtat tatgcaaacg gagaattcat tcaaatccac
     5821 ccgacagcca taccgggcga tgacaaatta agactgatga gtgaatcagc gcgtggtgaa
     5881 ggcgggcgcg tgtggacata taaagacggc aaaccatggt atttcctgga ggaaaaatat
     5941 ccggcatacg gaaacctggt gccgcgtgat attgcgacac gcgaaatatt tgatgtgtgt
     6001 gtgaaccaga agctcggcat taacggtgaa aacatggtat atctcgatct gtctcataaa
     6061 gatccgaaag agcttgatat taagcttggc ggcatcattg agatttatga gaaattcatg
     6121 ggagacgacc cgcgtaagct cccaatgaaa atcttcccgg cggtccatta ttctatgggc
     6181 ggtttatggg tggattacga tcaaatgaca aacatccctg gactgtttgc ggctggggaa
     6241 tgtgattatt ctatgcacgg cggcaaccgc ttgggagcga actccctgct gtctgcgatt
     6301 tacggaggca tggtggccgg tccgaatgcg gtgaaatatg taaacggctt agaatcttca
     6361 gcggaagaca tgtcttcatc tttattcgac gctcacgtta agaaagaaga agaaaaatgg
     6421 gctgatatta tgagtatgga cggaaccgaa aatgcctatg ttcttcacaa agagctcggt
     6481 gagtggatga cggcgaacgt aacggttgtc cgccataatg acaagctttt gaaaacggac
     6541 gacaaaattc aggagttaat ggagcgcttc aaaaagatca acatcaatga cacgacaaaa
     6601 tggagcaacc agggagcgat gttcacacgc cagttctcga acatgcttca gcttgcgagg
     6661 gtgattaccc ttggcgcata caaccgtaat gaaagccggg gcgcccatta taaaccggat
     6721 tatcctgaac gtaatgatga tgaatggctc aaaacaacaa tggctaaaca tgtaagcccg
     6781 tatgaagcgc cggaatttga gtatcaggat gtcgatgtat cactgataac gcctcggaaa
     6841 cgggattact cgaagaagaa ggtggcgaaa taatcatgag tgaacaaaaa accatacgat
     6901 ttattatcac acgtcaagat acagccgaca gcacgcctta cgatgaagaa tttgagattc
     6961 cataccgccc gaatctgaac gtcatttccg ctctgatgga aatccgccgg aatccggtta
     7021 atgtcaaagg tgagaagaca acccctgtca catgggatat gaactgcctt gaggaagtat
     7081 gcggcgcatg ttcaatggtc ataaacggaa aaccccgcca gtcttgtacg gcgcttattg
     7141 accagcttga acagccgatc cgtttaaaac caatgaaaac attcccagtc gttcgtgatt
     7201 tgcaggttga tcgcagcaga atgtttgatt cattgaaaaa agttaaagca tggataccga
     7261 ttgatggtac gtacgattta ggaccggggc cgagaatgcc ggaaaaacgc cgtcaatggg
     7321 catatgaatt atcaaaatgc atgacatgcg gcgtctgcct tgaagcttgc ccgaatgtga
     7381 acagcaaatc gaagttcatg gggcctgcac cgatgtcgca agtccgcctg tttaacgcgc
     7441 atccgacagg cgccatgaat aaatctgaac gattagaagc attaatggat gaaggcggcc
     7501 ttcaagattg cggcaactcg caaaactgtg ttcaatcctg tccgaagggg attccgctta
     7561 ccacttcgat tgcagccttg aatagagata caaacttaca agcgttccgc aatttcttcg
     7621 gaagcgacag agtataaaaa gaaaaaacct cttccgcatg ggagaggttt ttttaaacaa
     7681 taaggagatg aaaaaagatg aagcttcccg cttatattga tatgccgttt caagaatgga
     7741 aaacatcctt ttcttttttt aatgaggtat ccgtaagatt ttccgagaca gacatgtttg
     7801 ggcatatgaa taatgtaacc ccttttatat attttgagga ggcgcggatt tcttatttta
     7861 aaaagctgaa tatgatgagt gaaaacaaac agaccatgac agtcgtggca agccagcaat
     7921 gcgattattt gcgccaagtc atgccttatg aagagttgcg catctatgtg aaaacaagcg
     7981 cagtcggcag ttcatctctt accttgcact atctcggaga gaacctcgaa ggcgagccct
     8041 gcttcaccgg ggcagtcgtg atggttcaag tctcaaagga aagtggcaag gctgtcagct
     8101 ggacagatga ggagaaagaa acgctccttc atacacgata aactaattat cttgtaaacg
     8161 tcacctcctg cgcccttctt acatatgata tctcgactat atcaaaaccc attcgtttct
     8221 gattcgctct caccttagca aggagggtta caatacttga aggagaaaga atttcaatcg
     8281 aagccgctgc taacgaaaag agaaagagaa gtgttcgaat tgctcgttca agataaggca
     8341 acaaaggaga ttgcaagcga gctatttatc agtgagaaaa ccgttcgaaa ccatatttca
     8401 aatgccatgc agaaattggg tgtgaaaggg cgttcgcaag ccgttgttga gcttcttaga
     8461 atgggtgagc tagagcttta atccttgccg gtattccttc ttttggaagg agccggttat
     8521 tgctgtttgt ttggaacatt cgaaaccata tttggaatgc tgtgcaaaac gtaggcaagt
     8581 cataaattaa attttatttc ttgatgttgt ttgactaaag tcctctattt ctctcctgcg
     8641 agtcttgcat tttcttcaaa aaagaaggaa aatagacacg gaacgctttt gtgcgtaaga
     8701 gatccttgag tgagggatgg acaaatgaca tcaaaacctt tggagcatgt tgcggatatt
     8761 gaaaagtcac tccgccacat tgccgcgatc attaagcaaa aaggacgaga aatccttaac
     8821 caatatgcga ttacgccgcc gcaatttgtc ggcttgcaat ggctttatga attaggagat
     8881 atgacaatcg gtgaattatc gggcaaaatg tatctggcat gcagcacgac aacggactta
     8941 atcgaccgca tgcaaaaaaa tgagcttgtt gagcgggtca aggacccggc ggacagacgt
     9001 gttgtccgga tacatctgct gcctgaagga gaacggatta tccaagaggt cattacaaaa
     9061 agacaggaat atctgcgtga tatgttcgaa tcgtttacag atgaagaaat agccatcttc
     9121 gaaaaatctt tgatgaaact gcagcatgaa atgaagagaa aatgaggcga ttttgttgga
     9181 acaaccaata ggagtcattg attccggggt tggcggttta accgttgcga aggaaatcat
     9241 gagacagcta cctaaagaaa atattatcta cgtcggggat acgaaacggt gtccttatgg
     9301 gccgcgccct gaagaagagg tgcttcagta tacgtgggag ctgacgaatt atttactcga
     9361 aaaccaccac atcaaaatgc tcgtgatcgc ctgtaacaca gcaacagcga tcgcattgga
     9421 tgacatccag cgaagcgtcg gtataccggt ggtcggagtg atccagcctg gtgcgagagc
     9481 agcgataaaa gtgacggata atcagcatat cggtgtcatc ggcacagaga atacgattaa
     9541 gagcaatgca tacgaagagg cgcttttggc attaaatcct gatctgaagg ttgaaaacct
     9601 tgcctgcccg ctgcttgtgc cttttgtgga aagcgggaag tttcttgaca aaacagcaga
     9661 cgagattgtc aaaacctcgc tgtatccgtt aaaagataca tcgattgatt cgctgatttt
     9721 aggctgcacc cactatccca ttttaaaaga agccattcaa agatatatgg gagaacacgt
     9781 taacattatt tcgtccggcg atgaaacagc ctgggaagtc agcacgattc tctcgtataa
     9841 agggctgctg aaccagtctg cgaatgcccc tgatcatcag ttcttgacaa caggagcgcg
     9901 tgatcagttt gcgaaaatcg cagacgattg gtttggccat gaggtgggcc atgtggaatg
     9961 catctcactg caagaaccga ttagaagata gttttccccg caacggtatg ttgcgggttt
    10021 ttttctgttt tgccggaatt cttcggtcta tttcctaaag aggctcgtat acataatagt
    10081 acaaacatcc ttaggaggga aaagtatgct gaaaaaagga cctgcagtca ttggtgccac
    10141 ttgtctcacc tctgccttgc ttttatccgg atgcggtttg tttcaatctg ataaggcagc
    10201 cgaggaaatt gatccgcctc aagacgttac attcgtgaac gatgaagcgg gtgccaattc
    10261 aaatacaaca gcagccaaaa aaacagaaag tgaaaaaagc gataccgcaa aagcggatca
    10321 agcctcatct actgttatga gggagcttta tctcattgat aaaaacggat atgttgttgc
    10381 gcaaacgctg cctctcccta aaagtgagag cacggctaag caggcgcttg aatacctcgt
    10441 acagggcggg cctgtgtctg aaattcttcc gaatggcttc agagctgtat tgccggctga
    10501 caccaccgtt aacgttgaca tcaaaaaaga tggaaccgcg atagctgatt tctctaatga
    10561 gttcaaaaat tataagaaag aagacgaaca gaaaatcgtt caatctgtga cgtggacact
    10621 gacgcaattt agttcgatag ataaagtgaa gctgagaata aacgggcatg aactgaagga
    10681 gatgcctgta ggggggacgc cgatctcaga tgatttaagc cgcaaagacg gcattaattt
    10741 ggaaacagcc ggtgtaaatg atctcactgc tacccatccg ctgacagtct actacttggc
    10801 ggaaaacgaa gacagtgaat actacgtgcc ggtgaccaaa cgaatcgaca attcggaaaa
    10861 agacgacatc acggcagcca tcaatgaatt ggctaaaggg ccaagcaagg tgagcgggct
    10921 gttaacagac ttcagtgaag atgtaaagct ggtcagcaaa ccgaaaatca aagacgggcg
    10981 cgtgacgttg gatttcaatc aatctatatt cggcagcgcc gatgagaaga cgaaaatgat
    11041 ttcttcagaa gtgctgaaca gcattgtgct gacgttaaca gaacagccgg aagtaaaaag
    11101 cgtttctgtt aaagtgaacg gaaaatcaga gcttgtaaat gaaaaaggcg aaaagctcac
    11161 agaaccggtc tccagacctt ctcaagtgaa tacgggtagt ttttaaattg ggatttttga
    11221 tatactagaa agaaagaggt tagcgttccg gctgcctctt tctttattca attccgggac
    11281 aaaaatggtt tatgtacata caatcggagg taaaacatga gacatgacgg aagacaacat
    11341 gatgagctgc gcccaatcac attcgatttg gattttatca gccatccgga aggttctgtt
    11401 ctaataacag cgggaaatac aaaagtaatc tgcaatgcgt ccgttgagga tcgcgtgccg
    11461 ccgtttttgc ggggcggggg aaaaggctgg attactgctg aatacagcat gctgccgcgg
    11521 gcaacaaacc aaagaacaat cagagaatct tctaagggga aaatttccgg cagaacaatg
    11581 gagatccaac gcctgatcgg ccgcgcgctt cgagctgttg tagatctgga aaagctcggt
    11641 gaacggacga tttggattga ctgtgatgtc attcaagctg atggaggaac tagaacagct
    11701 tccattacag gcgcatttct tgctatggcg attgcgattg gcaagctgat caaagcagga
    11761 acaatcaaga caaatccgat cactgatttt cttgctgcga tctctgttgg aattgataag
    11821 gaacagggaa ttttgttaga tttaaattat gaagaagatt cctccgctga agttgacatg
    11881 aatgtcatca tgacaggcag cggccgtttt gtggaactgc agggaaccgg ggaagaggcg
    11941 actttttcaa gagaggatct gaacggtctt ctgggtcttg cggaaaaagg aattcaagag
    12001 ctgattgaca agcaaaaaga agtgctgggt gattctctgc cagaactgaa ataaagacag
    12061 aaaggcttga tcatcatgaa agaagcaatt attgcaacac ataatccggg aaaagtgaag
    12121 gaattcaaag aaattcttga gccaagaggc tatgatgtca aatctttagc tgaaattgga
    12181 ttcacagagg aaattgaaga aacaggccat acatttgaag aaaatgccat tctgaaagcg
    12241 gaagctgttg ccaaagcagt gaacaaaatg gtgattgcgg acgactccgg tctatccatc
    12301 gataatcttg gcggcagacc cggggtttat tcagcccgct atgcagggga acagaaagac
    12361 gaccaggcaa atatcgaaaa agtgctcagc gagctgaaag gtatcgaaaa agaacagcgc
    12421 accgcccgtt tccgctgcgc actggccgtg agtattcccg gagaggaaac aaaaacagtc
    12481 gaaggccatg ttgaagggta tattgccgaa gaaccgagag gagaatatgg ctttggctat
    12541 gacccaatct ttatcgtgaa agataaagat aagacaatgg ctgaactgac aagtgatgaa
    12601 aaaaataaaa tcagccatag ggctgacgcg cttaaaaagc tgtctaagct tttggaggca
    12661 taaggaggaa gcttgtacat gaacgtgctg attatcagtg acagccatgg gcttgaagaa
    12721 gaactccaaa ccattgcgaa acggcatgag gcagaagttg atctcatgat tcattgcggg
    12781 gactctgagc ttgaaacgag gcatcctgca ttggagcctt atgcggttgt aaaaggcaat
    12841 tgcgattttg ccggcgattt taaggacgag cttcttctga atgccggctc aagaaaaata
    12901 ctggtcacac acggccacct tcacggtata aaacagacct tgttaaacgt atactatcgt
    12961 gcagaggagc tcggagcgga tattatctgc ttcgggcatt cgcacatcgc gggaagcgaa
    13021 gtgctgcgcg aaaaactgat gattaaccca ggcagcatcc ggcttccgag ggtgcgcagg
    13081 acagaaagct atgctatact gacattagaa aatgatgctg cgacagtccg tttttacgac
    13141 caagcaggca atgaaattga ggatctgcaa aatcgagtca cactatgaaa atgtcatgag
    13201 gaagaaaatt ttcttcctca tgaaaaaaat tctaaaaaac cgttgactta ttattgcatc
    13261 ccatatataa taaatcttgt cgctgatatt taaagcaaaa aataaaacgt gtcccagtag
    13321 ctcagctgga tagagcaacg gccttctaag ccgtcggtcg ggagttcgaa tctctcctgg
    13381 gacgtaccaa aagaaaaacc tcaaatccat ttaggatttg aggttttttg ttgtcgtctt
    13441 atgatttgat tttcatttgt tatttaacgg atcatcatcc aagccgtcaa cttttccttc
    13501 tttattcaga cgaggttctt cttttttcac agtttcagaa atatgttcat tttcttcaac
    13561 agtgcgtttg ccgacaacca cttcatcagt gacaaccggt tttttagtca cttccagctt
    13621 ttcctcaacg attggaactc tgatctcttc cgaatcgttg acgggagcag cgtccgtttt
    13681 attttcatcc actggacggc gttcgacata aatttcatca tgtctcacag gaatgtccat
    13741 atctcttttt tctgttttca cttcttttcc tatttctact tcgccggttt gaacgtcttc
    13801 cttatcgacc ttcagctgtt cttctcggag cggcatcgtt ttttcttctt ttgttgtata
    13861 atccaattca tttgtgcctg aaaagccgcc tgaaagggca ttgccgttat caacaggagc
    13921 aattacatct gcatctgtat cgacggctac caaaagtttt ccgtcatcca aatcttcttg
    13981 atacttgtct atttcatcag ttttaatatc caagtcggat aatgctttgc tgtgtgtagc
    14041 agtatcatcc attgtgaaat aatctttcag tttatcgaaa aaagattcag attcgtcctg
    14101 atgtgcatcg atggcttgat tgacttctgt tcctgtacgt gactccaaat aatctgtatc
    14161 tcgccggctt gtcacaacag aaatgtcatc agaatcatag ccttttgtga gtaagccttc
    14221 aatcgctgcg atggtttcct gcggagtttc atatacacca actatgcttt tcatatcaat
    14281 ctcctccttt atgaatttgc atgatatcgt tcatgtcgtt tgtaattccc gctgttcttt
    14341 gaattaaaca aaattgaaaa cattggcgtg tatcataaag gtgaaaaatg tgtgaatata
    14401 aaaaaaagat agataagaca gaccttcccc tgcacttatc tatccttata aaatcgtctc
    14461 acaattcctt cgtcataaac acactgtttg gatcttcatc gtagtctgca aacggttcac
    14521 agtactgaaa aacgaagctt tcatacaact ttcttgccgg ctcaaacgaa gccattgaac
    14581 ccgtctctaa gcttaaccgc tcatagcctc gcttctcggc ttcttcaatg atgtgctgga
    14641 gaacttgttt ggcaacgcct tttcttaaat gtgatgcaga tgttcgcatt gatttgattt
    14701 ctccatgccg ggtgtccagt tcttttagcg ctccgcagcc agctagttca tcaccttccc
    14761 atgcgctcca aaatgttatt tcaggccctc ttagtttttc taaacctaag gcatgaatgc
    14821 tttctggcgg ggacataagc gtcatgttat gtaaatgctc attcacaagt gagaccacct
    14881 gacgtccagt taaatcgtct atttttatat gcaattttat tcctcctcga aaacttacgg
    14941 gttgtgcaga atatcgttca attcatccca tcctgtttcc aaatataaag acagaaaatg
    15001 tgactgtatt tgtgaagtcg ttttaaaaca ataaaaggac cgcaatagat gttcggccct
    15061 tgtggtcttc tttaatatct aaagcctccg tgtacgcctg gcgccccgct gaatccgccg
    15121 gcatgtatcg ctggagcact taagctgccg ccatggccgc taaagcctgc acctgaaaat
    15181 tgctgtccgt aaaatcctga agcgtatggg aatgaggagt acatagcaga gggagtggtt
    15241 aacgggctat atgcctggct gaacggctgt ccgtatccgt agcctccaaa tggctgatgg
    15301 ctttgctggt aaaaggaagg gacagcagga tagtactgct gcggaaagct cgggaagctc
    15361 ggaaagcctg cagggaatcc ttgcatgtct gctaatgatt tattcatcgt atcacctttt
    15421 ctttgcaaga taccattaat gtatgccggg gaataatagg ggtgcctatc cgaaattgaa
    15481 atggattgca agatgatctg tcagactcaa tccatatacg aaccatagcg tgttataaaa
    15541 tcttacatgt ttatataaaa ttaaataatt ctggtgtatt cttgatggat taataaaaaa
    15601 attataaaaa cttttaacat ttgcaattcc ttttgtacca ataatgaaag cgtatacaat
    15661 atagattgat taatcaaaat tgtctaataa ttttaaaaaa tgctgttgac actgcgtcca
    15721 aagcggcgta atatgagttc aacaaaagat aaacgcaagc ttcacaagcg aaaatcatcg
    15781 caatatgatt ctaaaaaaat gaaaaacaaa cgaccttctt gaacagctgg aaagccgttc
    15841 cgaaggctga atatgaaaag cgcagatgag gataagtagc cttgaaaaag ctttccacag
    15901 agaaccgggt tagctgagaa ccggcgaagc tttacaaggt gaactcgcct cagagtgcca
    15961 gtctgaaatg acagtaggac ttggccgggt gaacttgatt cactcgttac taaagcggat
    16021 agaaatatcc atgagacggc cgattaacag gccgtaaaca agggtggtac cgcggaaaga
    16081 aaagcctttt cgcccctttt agctatcgca gttactgcgc ggctgattgt gggcggaagg
    16141 gcttttttta ttgaataatc agctataaag ctaataaaag attgatcttt agaggatgaa
    16201 aatccaaaag gaggaactaa aatggggact aatgtacagg tggattcagc atctgccaaa
    16261 tgtacacaga cgatgagcgg agcattaatg ctgattgaat cattaaaaaa agagaaagta
    16321 gaaatgatct tcggttatcc gggcggggct gtgcttccga tttacgataa gctatacaat
    16381 tcagggttgg tacatatcct tccccgtcac gaacaaggag caattcatgc agcggaggga
    16441 tacgcaagag tctccggaaa accgggtgtc gtcattgcca cgtcaggacc gggagcgaca
    16501 aaccttgtta caggccttgc tgatgccatg attgattcat tgcctttagt cgtctttaca
    16561 gggcaggtag caacctctgt aatcgggagc gatgcatttc aggaagcgga cattttaggg
    16621 attacgatgc cagtaacaaa acacagctac caggttcgcc agccggaaga tctgccgcgc
    16681 atcattaaag aagcgttcca tattgcaaca actggaagac ccggacctgt attgattgat
    16741 attccgaaag atgtagcaac aattgaagga gaattcagct acgatcatga gatgaatctc
    16801 ccgggatacc agccgacaac agagccgaat tatttgcaga tccgcaagct tgtggaagcc
    16861 gtgagcagtg cgaaaaaacc ggtgatccta gcgggtgcgg gcgtactgca cggaaaagcg
    16921 tcagaagaat taaaaaatta tgctgaacag cagcaaatcc ctgtggcaca cacccttttg
    16981 gggctcggag gcttcccggc tgaccatccg cttttcctgg ggatggcggg gatgcacggt
    17041 acttatacag ccaatatggc ccttcatgaa tgtgatctat taatcagtat cggcgcccgt
    17101 tttgatgacc gtgtcacagg aaacctgaaa cactttgcca gaaacgcaaa gattgctcac
    17161 atcgatattg atccagctga aatcggaaaa atcatgaaaa cacagattcc tgtagtcgga
    17221 gacagcaaaa ttgtcctgca ggagctgatc aaacaagacg gcaaacaaag cgattcaagc
    17281 gaatggaaaa aacagctcgc cgaatggaaa gaagagtatc cgctctggta tgtagataat
    17341 gaagaagaag gttttaaacc tcagaaattg attgaatata ttcatcaatt tacaaaagga
    17401 gaggccattg tcgcaacgga tgtaggccag catcaaatgt ggtcagcgca attttatccg
    17461 ttccaaaaag cagataaatg ggtcacgtca ggcggacttg gaacgatggg attcggtctt
    17521 ccggcggcga tcggcgcaca gctggccgaa aaagatgcta ctgttgtcgc ggttgtcgga
    17581 gacggcggat tccaaatgac gcttcaagaa ctcgatgtta ttcgcgaatt aaatcttccg
    17641 gtcaaggtag tgattttaaa taacgcttgt ctcggaatgg tcagacagtg gcaagaaatt
    17701 ttctatgaag aacgttattc ggaatccaaa ttcgcttctc agcctgactt cgtcaaattg
    17761 tccgaagcat acggcattaa aggcatcaga atttcatcag aagcggaagc aaaggaaaag
    17821 ctggaagagg cattgacatc aagagaacct gttgtcattg acgtgcgggt tgccagcgaa
    17881 gaaaaagtat tcccgatggt ggctccgggg aaagggctgc atgaaatggt gggggtgaaa
    17941 ccttgaaaag aattatcaca ttgactgtgg tgaaccgctc cggagtgtta aaccggatca
    18001 ccggtctatt cacaaaaagg cattacaaca ttgaaagcat tacagttgga cacacagaaa
    18061 cagccggcgt ttccagaatc accttcgtcg ttcacgttga aggagaaaat gatgttgaac
    18121 agttaacgaa acagctcaac aaacagattg atgtgctgaa agtcacagac atcacaaatc
    18181 aatcgattgt ccagagggag ctggccttaa tcaaggttgt ctccgcacct tcaacgagaa
    18241 cagagattaa tggaatcata gaaccgttta gagcctctgt cgttgatgtg agcagagaca
    18301 gcatcgttgt tcaggtgaca ggtgaatcta acaaaattga agcgcttatt gagttattaa
    18361 aaccttatgg cattaaagaa atcgcgagaa caggtacaac ggcttttgcg aggggaaccc
    18421 agcaaaaggc gtcatccaat aaaacaatat ctattgtata aaacataaca agggagagat
    18481 tgaaatggta aaagtatatt ataacggtga tatcaaagag aacgtattgg ctggaaaaac
    18541 agtagcggtt atcgggtacg gttcgcaagg ccacgcacat gctctgaacc ttaaagaaag
    18601 cggagtagac gtgatcgtcg gtgttagaca aggaaaatct ttcactcaag cccaagaaga
    18661 cggacataaa gtattttcag taaaagaagc ggcagcccaa gccgaaatca tcatggttct
    18721 gcttccggat gaacagcagc aaaaagtata cgaagctgaa atcaaagatg aattgacagc
    18781 aggaaaatca ttagtattcg ctcatggatt taacgtgcat ttccatcaaa ttgttcctcc
    18841 ggcggatgta gatgtattct tagtggcgcc taaaggaccg ggacacttgg tcagaagaac
    18901 atatgagcaa ggagccggcg tacctgcatt gttcgcaatc tatcaagatg tgactggaga
    18961 agcaagagac aaagccctcg cttatgctaa aggaatcggc ggcgcaagag cgggcgtatt
    19021 agaaacgaca tttaaagaag aaacagaaac agatttgttc ggtgagcaag cagttctttg
    19081 cggcggatta agcgcgcttg tcaaagcggg atttgaaaca ttaactgaag caggttatca
    19141 gcctgaactt gcatacttcg agtgtcttca tgagctgaaa ttaatcgtag accttatgta
    19201 cgaagaagga cttgcaggaa tgagatattc aatctctgac acagcacagt ggggagattt
    19261 cgtatcaggc cctcgcgttg tggacgctaa agtaaaagaa tctatgaaag aagtattaaa
    19321 agatatccaa aacggtacat tcgcaaaaga gtggatcgtc gaaaaccaag taaaccgtcc
    19381 tcgtttcaac gctatcaatg caagcgagaa cgaacatcaa atcgaagtag tgggaagaaa
    19441 gcttcgtgaa atgatgccgt ttgtgaaaca aggcaagaag aaggaagcgg tggtctccgt
    19501 tgcgcaaaat taattttttc gatacgacgc ttcgtgatgg tgaacagtcc cctggagtga
    19561 acttgaatac acaggagaaa cttgccatag ctaagcagct cgaaagactc ggggcagata
    19621 tcattgaagc gggatttccc gcttcgtccc gaggtgactt tttagctgtt caggaaatcg
    19681 caagaaccat taaaaattgt tcagtaactg gtctggcccg ttgtgtaaaa ggtgatattg
    19741 atgctgcttg ggaagcgtta aaagaaggtg ctcatccgag aattcatgtt tttatcgcca
    19801 catcggacat tcatttgaag cacaagctga aaatgacacg tgagcaagtc attgaaagag
    19861 cggttgaaat ggtgacatac gcaaaagaac gttttccgat tgtgcaatgg tcagcggaag
    19921 atgcctgccg cactgaactg ccgtttctag cagaaatcgt cgagaaagtg attgacgcag
    19981 gcgccagtgt tatcaatctt ccggacactg tcggctacct ggccccggcg gaatacggaa
    20041 atatcttcaa atatatgaaa gaaaacgttc cgaacattca caaagcaaag ctttcagccc
    20101 actgtcatga tgatttggga atggcagtcg caaactctct tgctgcgatt gaaaatggcg
    20161 ctgatcaaat cgaatgtgct gtgaacggga tcggtgaaag agccggaaac gcggcattag
    20221 aggaaattgc cgtagccctc cataccagaa aagatttcta ccaagtcgaa acaggtatta
    20281 cactgaacga gattaagaga acaagtgatt tagtaagcaa actgacaggc atggctgtcc
    20341 cgcgcaacaa agcggttgtt ggagataatg catttgctca tgaatcaggc atccatcagg
    20401 acggcttttt aaaggaaaaa tcgacttatg aaattatttc accggagctt gtcggtgtaa
    20461 ccgcagatgc gcttgtccta ggtaaacatt ccggacgcca cgcatttaaa gaccggctga
    20521 ctgctttagg attccaattt gacagtgaag agattaataa attctttatg atgttcaaag
    20581 agttgactga gaagaaaaaa gaaatcactg atgaggatct tgtttctctt attttagaag
    20641 aaaaagtaac agatcgcaag attgggtatg aatttctttc tctgcaagta cattacggaa
    20701 caagtcaggt ccctacggct actctttctt tgaaaaatca agaaaacgca gagcttattc
    20761 aggaagctgc aactggagct ggaagcgtgg aagcaatcta caatacgctt gagcgctgca
    20821 tcgataagga cgtggagctc ttagactacc gcattcagtc taacagaaaa ggcgaagatg
    20881 catttgccca ggtgtatgta agagttttgg tgaacggaaa agaatcggca gggcggggca
    20941 tagcgcaaga cgtattagaa gcatcagcga aagcctattt gaacgcagta aaccgtcaat
    21001 tggttttcca gtcgaatatg agcggattga aaaaccacac agctgtcgga tcataaaaga
    21061 aaggagaacg gttaacttga agaaacgtat tgctctattg cccggagacg ggatcggccc
    21121 tgaagtatta gaatcagcga cagacgtact gaaaagtgtt gccgaacgct ttaaccatga
    21181 atttgaattt gaatatggcc tgattggagg ggcggctatt gatgaacatc ataaccccct
    21241 cccggaggaa accgttgctg cttgtaaaaa tgcagacgcg atattgcttg gcgctgtcgg
    21301 cggaccgaaa tgggatcaaa atccttcgga actgagaccg gaaaaagggc tgctcagcat
    21361 cagaaaacag cttgatttgt ttgcgaattt gcggcctgtg aaggtatttg aaagcctttc
    21421 tgacgcttcg cctttgaaaa aagaatatat agataatgtt gatttcgtta tcgttcgtga
    21481 gctcacaggc ggcttgtatt tcggccagcc gagcaaacgc tatgtaaaca ctgaaggtga
    21541 gcaggaagca gtagatacac tgttttataa gcgaacggaa attgaacgag tgatcagaga
    21601 gggcttcaaa atggcggcag ccagaaaagg caaagtgacc tctgtagata aagcgaatgt
    21661 tcttgaatca agccggctgt ggcgtgaagt ggctgaggac gttgcacaag agtttcctga
    21721 tgtgaagctt gagcacatgc ttgtggataa cgcggctatg cagctaattt atgcaccgaa
    21781 tcaatttgat gtcgtggtga ctgaaaatat gttcggtgat attttaagcg atgaagcgtc
    21841 catgcttaca ggctcgctcg gaatgctccc gtcagccagc ctatcaagct ctggccttca
    21901 tctgtttgaa cctgttcatg gctccgcgcc tgatattgcc ggtaaaggga tggcaaatcc
    21961 gttcgcagcc atattgtcag cggcaatgct tttgagaaca tctttcgggc ttgaagagga
    22021 agcgaaagct gtagaagatg cggtaaacaa agtcttggct tccggaaaaa gaacaagaga
    22081 cttggcacgg ggtgaagagt tcagcagcac tcaggccatt acagaggaag ttaaggcagc
    22141 aatcatgagt gaaaatacaa tttctaatgt gtgacagctt acgttaagcg gtcttagctc
    22201 taggtagagg gaggaaataa aagatgatgc ctcgaacaat catcgaaaag atttgggatc
    22261 agcatattgt aaaacatggt gagggaaagc cggatcttct ctatattgat ttgcacctca
    22321 ttcatgaggt gacgtctcct caggcatttg aaggcttgag acaaaaggga agaaaggtca
    22381 gaagacccca aaacacattt gcgacaatgg accacaacat cccgactgtc aatcgttttg
    22441 agataaagga tgaagttgcg aaacgccagg taacggcgct tgaaagaaac tgtgaggaat
    22501 ttggcgtgcg ccttgccgat cttcacagtg tggatcaagg gattgtccat gtcgtcggac
    22561 ctgaactagg cttaacgctt ccagggaaaa cgattgtgtg cggtgacagt catacatcaa
    22621 cacatggcgc tttcggcgct cttgcatttg gaatcgggac gagtgaagtt gaacatgtcc
    22681 tttccacaca gacactttgg cagcagcgtc caaaaacact ggaagtgcgc gtagatggaa
    22741 cgcttcaaaa aggggtaacg gcaaaggatg tcatccttgc tgtcatcggc aaatacggtg
    22801 tgaaattcgg cacaggctac gtcattgaat acactgggga agtattcaga aatatgacga
    22861 tggatgaacg aatgactgtt tgtaacatgt caattgaagc aggagcaaga gcaggtttga
    22921 ttgcacctga tgaggtgacg tttgaatatt gcaaaaatcg caagtacacg ccaaaaggcg
    22981 aagaatttgc caaggccgta gaggaatgga aggcgctgcg cacagacccg ggcgctgttt
    23041 atgataaatc tatcgtcctt gacggcaaca aaatttcccc tatggtgaca tggggcatta
    23101 acccgggaat ggttcttcct gtcgattctg aagttcctgc gccggaaagc ttttctgcag
    23161 aagatgataa aaaagaagcg attcgcgctt atgaatatat gggactgact cctcatcaga
    23221 aaattgaaga cattaaagtg gagcacgtat ttatcggttc ctgcacgaat tcccgcatga
    23281 ctgaccttcg acaggctgct aatatgatca aagggaagaa ggtagctgac agcgtaaggg
    23341 ccatcgtcgt gcccggatct caaagcgtga agcttcaggc tgaaaaagaa gggcttgacc
    23401 agattttctt ggaagctgga tttgaatgga gagagtcagg ctgcagcatg tgtttgagta
    23461 tgaataatga tgttgttcct gagggagagc gctgtgcatc aacctctaac cgcaacttcg
    23521 agggcagaca aggaaaaggt gcaagaacac atctcgtcag cccggcaatg gctgcgatgg
    23581 ctgccattca cggacacttc gttgatgtca gaaagtttta tcaggaaaaa acagttgtgt
    23641 aaggagtgcg cgagatggaa cctttgaaat cacatacggg gaaagcagcc gtattaaatc
    23701 ggatcaatgt ggatacagac cagattattc ctaagcaatt tttgaagagg attgaaagaa
    23761 caggctacgg gcgttttgca ttctttgact ggagatatga tgcgaatggt gaaccgaacc
    23821 ctgaatttga attaaaccag cctgtttatc aaggagcttc cattttaata gcaggagaaa
    23881 acttcggctg cgggtcatcg cgtgaacatg ctccgtgggc acttgatgat tatgggttta
    23941 aaattatcat tgcgccgtca tttgctgata ttttccatca gaactgcttt aaaaacggca
    24001 tgcttccgat ccgcatgcca tatgacaatt ggaaacagct tgtcggccag tatgaaaacc
    24061 agtcattgca aatgactgtt gaccttgaaa atcagctgat tcatgacagt gaaggcaatc
    24121 aaatttcatt tgaagttgat ccgcattgga aagagatgct gattaacgga tatgatgaaa
    24181 tttccttaac gctgctgctg gaggatgaaa tcaagcaatt tgaatcacaa agaagctctt
    24241 ggcttcaagc ctgaaaaagc ggccggtatt tgtccggcgg ctttttttgc ctgatgaaac
    24301 ctttcatttc ttgtgtttgt tcacaggtgt tgatacactt gaacaaaata aatgcctgaa
    24361 aggaatatag gtatgacgca tgacaagaag aacgcaaaaa ttattccttt tcctcatctg
    24421 aaagaccgcc ttgtggaaaa agggatgtca tcactaaagg aaaaaaagta tcaagaagcg
    24481 cttgaactgt tttcagaagc gatgaaatat gatgatactg aatccgatct tcacttaggg
    24541 atggccatct gctttttaga gctgggcgag ctggaagagg caaaaagcgt gtgcgagaag
    24601 atgctcaaag aaggttatgg ccattatttt acggttttgc aggtgtacat gaccatctta
    24661 attcagctca aaaaatacga ggaagtcaaa agcaccattg aagccgtttt ggaagaaaat
    24721 cagctgccgg cagaaagcgc cgagcaattt tataagctgc tggatttcag ccggaaaatg
    24781 accgatccgg atcgtgagga cgaggcttgg gccgaagaat atgaggatac aattgacacc
    24841 gagaaagtgc tggcaagccc tgaggagcaa atgaatctca ttcattcctt aaaagaccgt
    24901 aacgtagcaa agtatacagg attgctcaaa acaatcctcc aagacccctc agcccatccg
    24961 attatcaaaa cgatgattgt catgctgttg gctgagcatg agtacagtaa acctgtacac
    25021 attagtaaat ttggcgagtc gttgacaatt gaaccgtcag agattgttcc gcctgatgcc
    25081 gcgccgattc tgcaccgtgt tctcagggtg ctggatgaga cacttggaaa tgaaaatcca
    25141 accttatatg cagcagtaga ggaattgtgg agaagacatt tgtacgtttt atatccgttc
    25201 cagccgaaat tgctgtcggc tgacctttgg gcggctgccc ttcataaagt cggttacgag
    25261 atgcacggga ttgaaattga aagcgaagaa cttcatatga tgtatgaatt taccgacaga
    25321 gaactcgatg aagcttgcac aatgttaaaa gatattgaag aaatttctta tttgtaaatc
    25381 gcgccatata gttgaaagcg ctatgtgtta tgttataata tagtggttgt atttgtgtat
    25441 aacgggttat aagaaatacg gttggacagg ctttgcagtt cattatttac atctatacat
    25501 aatgattctg atctttggca gctttgtttt tgttggacga agccgaatga ttgctttaga
    25561 atggaagacc gacacaacct gaatagattt ttggagggaa acacatgtct gtaaaatggg
    25621 aaaaacaaga aggcaacgaa ggcgttttaa cggttgaagt tgatgctgaa acgtttaaaa
    25681 cagcacttga tgatgcattt aaaaaagtag taaaacaagt ttcaattcct ggattccgta
    25741 aaggtaaaat tcctcgcgga ttattcgaac agcgctttgg cgtagaagct ctttaccaag
    25801 atgctttgga tattcttctt cctgtagaat accctaaagc ggttgaagaa gctggaatcg
    25861 agcctgtaga ccgtcctgaa atcgatgttg aaaaaatcga aaaaggcgaa agcttaatct
    25921 tcactgcgaa agtaacagta aaacctgaag tgaagcttgg cgaatacaaa ggcctaggca
    25981 ttgaaaaaga cgacacaact gtaactgacg aagatgttca aaacgaacta aaagcccttc
    26041 aagagcgtca agctgagctt gttgtaaaag aagaaggcgc cgttgaagaa ggaaacacag
    26101 ttgttcttga tttcgaagga ttcgttgacg gcgaagcttt cgaaggcgga aaagctgaaa
    26161 actactctct agaagtaggt tctggttcat tcatccctgg cttcgaagat caattagttg
    26221 gccttgaagc aggtgctgag aaggatgttg aagtgacatt ccctgaggag taccacgctg
    26281 aagatcttgc aggcaaacca gctgtgttta aagtgaaaat tcacgaaatc aaagcgaaag
    26341 agcttcctga gcttgacgat gaattcgcaa aagatatcga tgaagaagtg gaaacacttg
    26401 ctgaattaac tgaaaaaaca aagaaacgtt tagaagaagc aaaagaaaac gaagctgacg
    26461 ctaaattgcg tgaagagctt gttctgaaag cttctgaaaa tgctgaaatc gatgtgcctc
    26521 aagcaatggt cgacactgag cttgaccgca tgctgaaaga attcgaacag cgtctgcaaa
    26581 tgcaaggcat gaaccttgag ctttacactc aattctcagg ccaagatgaa gctgcgctta
    26641 aagagcaaat gaaagaagat gctgaaaaac gcgtaaaatc taacctgact cttgaggcga
    26701 ttgcgaaagc ggaaaacctt gaagtatcag atgaggaagt tgatgctgag cttacaaaaa
    26761 tggctgaagc atacaacatg cctgttgaaa atattaaaca agccatcggt tctactgacg
    26821 cgatgaaaga agatttaaaa gttcgcaaag caattgattt tcttgtagaa aaccgttaat
    26881 atggtgcata ataatagtac taataaaaca gggcgcgaat cattcgtgcc ttgttttgta
    26941 caattatgag ttatctcttt ttcttggggc aatatagtta atgcagggct gttttttgtc
    27001 atacatatag aatgtgcaag tcagaaacac attgttaccg tctttttgga aagtatggta
    27061 aaatgcaata catactcgtt cgtttcaaga atcattttct tttgctctgc cggtaaaaga
    27121 aaaagtgaga caagattaag gggtgaaaga atgtttaaat ttaacgagga aaaaggacaa
    27181 ttaaaatgct cgttctgtgg aaaaacacaa gatcaggttc gtaagcttgt agctggacct
    27241 ggtgtatata tatgtgacga atgtatcgaa ctctgcactg aaattgtaga ggaagaactc
    27301 ggaacagaag aagaagtaga atttaaagac gtaccaaagc ctcaggaaat tcgtgaaatt
    27361 ttgaatgaat atgtcatcgg ccaagatcaa gcgaagaaat cacttgctgt tgctgtgtat
    27421 aaccactata agcgcattaa ctctaacagc aaagttgatg atgttgagct ctcaaaaagt
    27481 aatatttcat taatcggccc tacgggaagc ggtaaaaccc ttctggcgca aacattggct
    27541 cgcattttaa atgtgccgtt tgcgattgcg gacgctacat ctttgactga agctggatac
    27601 gtgggtgaag atgtagagaa tattctcttg aagctcatcc aagctgctga ttatgatgtg
    27661 gaaaaagccg aaaaaggcat tatctatatt gatgaaatcg ataaagtggc tagaaaatct
    27721 gaaaacccgt ctatcacacg tgatgtgtca ggtgagggtg tacagcaggc attgcttaaa
    27781 attcttgagg gtacagtggc aagcgtaccg cctcaaggtg gacgtaagca tcctcatcaa
    27841 gaattcattc aaattgacac aacaaatatt ttgttcattt gcggcggagc tttcgatggt
    27901 atcgaacaaa tcatcaaacg ccgtttaggc caaaaagtga ttggattcgg tgccgacaat
    27961 aaagctgctg atcttgagaa agaagatctt ctttcaaaag tgcttcctga agatttgctc
    28021 cgtttcgggt taattcctga atttatcgga cgtcttccgg ttattgcaag ccttgaaaag
    28081 cttgacgaag aagcattggt tgcgatctta acaaaaccga aaaacgctct agttaagcaa
    28141 ttcaagaaaa tgcttgagct tgacaacgtt gagcttgagt ttgaagaaga agcgctttct
    28201 gaaattgcta aaaaagcaat tgaacgcaag actggagcac gcggactccg ttccatcatt
    28261 gaaggcatca tgcttgatgt gatgtttgag ctgccttctc gtgatgacat tgaaaaatgt
    28321 gtaatcaccg gggcaactgt gacacacgga gagcctcctc gcctcttatt aaaagacggc
    28381 actgaggtaa gccaagataa aacatctgca taaagataag cacaaacctc ctgagtggta
    28441 acactcagga ggtttttttg catgcaactc ttccggaaaa acgtttattc ccgtcttcta
    28501 tgggagatac tagcaatcag aggaatgaat tggatacata aattgttttt caggagggac
    28561 caccatgagt tggacaggga tcgcgttatt tattcagctg ttttttggga tcatcatcgg
    28621 tttgtatttt tggaatttgc ttaaaaatca aaggacacaa aaggtcacga tagataaaga
    28681 atcaaagaag gaaatggagc agcttcggaa aatgcgcgct atcagcttgt ccgagccatt
    28741 atctgagaag gtccgcccca aaagctttaa agatatcgtc ggacaggaag acggcattaa
    28801 agcattaaag gcggctttat gcgggccaaa tcctcagcat gtgattgtct atgggccacc
    28861 gggagttggg aaaacggctg ctgcgcggct tgtgttggaa gaagcaaaaa aacataaaca
    28921 atcaccgttt aaagagcagg ctgtctttgt ggaactcgat gcgacaacag cccgttttga
    28981 tgaaagagga attgccgatc cgctcatcgg ctctgtccat gacccgatat accaaggggc
    29041 cggagcgatg ggacaggctg ggattccgca gccgaagcag ggagctgtca cccatgccca
    29101 tggcggtgtg ctgtttattg atgaaatagg ggagctgcat cctattcaaa tgaataaaat
    29161 gctgaaggtg cttgaggaca gaaaagtctt tttagatagt gcgtattaca gtgaggaaaa
    29221 tacacaaatt ccgaatcata ttcatgatat ttttcaaaat gggctgccgg ctgattttcg
    29281 cttgattggc gcgaccacga gaatgccaaa cgaaattccg ccagctatcc ggtcccgctg
    29341 tttggaggtt tttttccgcg agcttgaaaa ggaggagttg aaaacggttg ccaaaacagc
    29401 agcggataaa attgaaaaaa atatctccga agaaggactg gatcttttga ccagctacac
    29461 gcggaacggg cgggaagccg tcaatatgat tcaaatcgca gcggggatgg ctg
//
