LOCUS       gnlProkkaKLDCOAMH_1    13557 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KLDCOAMH_1.
ACCESSION   gnlProkkaKLDCOAMH_1
VERSION     gnlProkkaKLDCOAMH_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 02:22:01
            Original ID  :: gnl|Prokka|KLDCOAMH_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 165861
            Orig. end    :: 179418
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13557
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8557]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8557
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..13557
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13557
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3971..4489
                     /locus_tag="ctg1_145"
                     /transl_table=11
                     /translation="MSQQQEYWFAARTRKDQELTTRDALEKIGVEYFLPTQFVIRQLKY
                     RRRRVEVPVIRNLIFVHATKEFACAIANEYGVRLFYMRDFDTKSMLIVPDKQMKDFMFV
                     MNLDPAAVILNDDCFAVGTKVQVIKGDFCGVEGELASLSNRTYVTIRIRGVLSASVKVP
                     KSYLRILAP"
     CDS             4525..4998
                     /locus_tag="ctg1_146"
                     /transl_table=11
                     /translation="MTQIHELQHVAHELLYLGADGSPIYTDSFRQLNTEVLQKSDALFA
                     LKGENPEEEARLCLALLMGYNATIYDYGDKESKKQVILDRSLLVLESLPSSLLKCQLLT
                     YCYGEVFEEELAKEAHAIIDGWKDRELLEEEREIVENLRILEEPPYLFSNKSC"
     CDS             5001..6302
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 200.2;
                     E-value: 7e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_147"
                     /sec_met_domain="CTP_transf_like (E-value: 3e-15, bitscore:
                     50.2, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 5.2e-118, bitscore:
                     386.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.3e-63, bitscore:
                     207.4, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKVYVGMSADIIHPGHLNIIHEAQKLGNVTVGVLTDAAIASYK
                     RLPYLTYEQRSLIVQNLKGVDEVIPQTTLDYIPNLELLKPDFVVHGDDWKEGVQKETRQ
                     RVIETLSKWGGQVIDIPYTQGISSTKLNSKLKEIGTTPEVRLKRLKRLIEAKSIVRICE
                     SHSGLTGLIIENTSVEVNGMKREFDGMWSSSLTDSTSKGKPDIEAVDLTTRLHDLNDAL
                     ECTTKPVIFDGDTGGKIEHFVFTVRTLERLGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCDKISAGKRAQITDDFMIIARIESFIAGKGLDDAMKRALAYIEAGADGIMIHSKD
                     KSGEDIRLFCKALREVNQSIPIVVVPTTYNHITDEELSTWGINVVIYANHMLRSAYPAM
                     LNTAKSILLHARSYEANDLCMPVKDILELIPGTK"
     CDS             6310..7434
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 67.9;
                     E-value: 1.2e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_148"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.7e-15, bitscore:
                     50.6, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9.5e-21, bitscore:
                     67.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISPELFINSLVQNELNFFTGVPDSLLKHICAYITDHIASNSHIV
                     AANEGAAIGLAVGYHLATNKIPVVYMQNSGIGNSINPLLSLVDKEVYNIPLLLVGWRGE
                     PGVKDEPQHIKQGKVTIPLFDSMRIKNQILSKDKSDFLQQLNVALEYIRETNEPFVFII
                     QKETFSDYKLQTPNNNALLLDRETAIKIIVSSISKNDIVVSTTGMISRELFEYRDNMGE
                     SHEKDFLTVGSMGHASQIALGIALQKKARTVYCFDGDGAVLMHMGGLTTIGSIKPSNYI
                     HVLFNNGAHDSVGGQPTVGFEVDFTKIALACGYKYALVVESASSLNEVLKTVNEMQGPV
                     FLEVKVKKGARKDLGRPTITPIQNKDSFMDFLKR"
     CDS             7436..8557
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Fe-ADH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_149"
                     /sec_met_domain="Fe-ADH (E-value: 3.8e-84, bitscore: 276.0,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQRIYIGEASLNNLDIILQEYSAKKVFLVRGKKSYELCGAQSRL
                     NSILKKVGVQIFEFHDFEENPKIEDLDRGLLQLRVYHPDLILAIGGGSVLDMAKLLRFF
                     YSYSGNKIGRVFEKIENLLPLIVIPTTAGTGSEATSFAVLYKNKVKYSVSHEDILPEIA
                     FIDPYFTYNISQYLTACTGFDALAQAIEAYWNLNATNESDVFAVKAIKLLWPNLPLAVN
                     NPTKEVRNSMSEGAYWAGCAINITKTTAPHAFSYPFTTYYGYPHGHAVALTFPFFMEYN
                     VGSILLKHGTVFDKMIRLMEILNITNVNECKSLLCDYIENIGLDLKLPANFDHRIILSN
                     INVQRLSNNPVRIDGAVAKTALNTLCIKDDDKD"
     CDS             8563..9807
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_150"
                     /sec_met_domain="Polysacc_synt (E-value: 1.2e-36, bitscore:
                     120.1, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKKSLDSYKVIFQNTFYLSIIEAIRLIMPFIALPYIITTIGAT
                     NYGIIIFSQTIVSYFSIVINWGLDVTSVREVSLNRGSLKKMSLIVSTVFTIKFILFGLC
                     FSIFMICLFFIPFFQQYRIIYLYAFLSCFSEVIIPVWFFQGIEKMKYLTYIRTTSIVLY
                     TILVFTFIKKEMDFTLLALLQSLANITAGVFSLILLLIFCRVKFVFPTFRVMKETFCNS
                     TPFFVSRVSFLLNTNIAKTMSGLFLNMHTVAAFDLSQKILSFVSVPIQMLNQAIYPHVA
                     KNPIKSFSVKMLYVIAALSLILSVLLFFLAPYIILYFSEQLYAEALIFIRILCLYVFCF
                     GINTYLGTPLLVAYGFYKPFNFSVIYSTLFVCSLYGILYVFNLLGGECFALAMFLTELF
                     ILIYRFYYCLKFKLI"
     CDS             9813..10598
                     /locus_tag="ctg1_151"
                     /transl_table=11
                     /translation="MEKISNYNTDGTMLRKQQERMFEMLCVIDDICVKNEINYWLSGGT
                     LLGAVRHGGFIPWDDDLDIQLMKDDYNKLLGLLKTELPEQYQLQTSKTDRNYFARYAKV
                     RDVNSLLEDSDYTLGYKYKGIFIDIFSVEKANKFLVKISAFMQWYLLISLLPMVHKKTK
                     MQLNLFSLWNKFLGTFYSGFRLFGKLFAKKINYSYGVYYPLNCDYTTIFPLTTIEFEGR
                     MFKVPGNYNLYLCNIYGDYMKLPPEEERENHNIRVVHIV"
     CDS             10613..11938
                     /locus_tag="ctg1_152"
                     /transl_table=11
                     /translation="MLIVILLTLILIYILYKIYKKKKVHQFLLIYFAFSAFLWVIFPSI
                     VSLIGDRYKQELVVKENVFITYAIYEFLFYIILLLLLYRFPLCKPFYYGKYIPNTSSSI
                     KRIWFVLSLFLIINIIKQISSNVTYSEVNDSTILAEQETNLFSIFSNFSICLYLTIILF
                     YNKLYSKRIIFFSWLLLSLNIITVLAHGARMQVIFYLFVFVYYLFSSALNKKRFFLYMS
                     FLIGIIYLCSYILPAVAYIRSGGNFTVEDLRKSYENYGEANAFVLQLLIKSNSINTGAI
                     LVEETKEKPYLNPYINSIYSFCPSILFPGKRPLAGSSDGTIDGFPTRLAAEYISGDSRF
                     FNVGISTSATALWHGGILFYVINLIIVFFWYRFLNSLMFYENYYAKLLVVYFTVLGYFI
                     LPTADVLIRDLLKQPFFYAFFIFISRGGLIKDWVRSLKRHIA"
     CDS             11967..12938
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_153"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.7e-37,
                     bitscore: 120.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNPILLSIVIPVYNVELYIERCLLSCLNQDLSISQYEIILIDDG
                     SPDSSIDKISKWLDRKNITLLTQPNSGLSVARNNGLLHAKGKYVWFVDSDDWILENCLQ
                     EIAGYMVAGIDIITFCAADFINDKFYRRFEYITGVNKKIEGRDLLKRGTCQHCVPFSIY
                     RKRFLEQNHLFFLPNIFHEDTEFSPRAYYLANHVFCINKVFYYVYHNPNSITRTFNPKK
                     SFDLLIVSHSLSIFMLDVTPEYKSCFNNLISLSINAAINGIVTAKSEISRFIVDLTARG
                     LYRNMLNAGKLRYKIEGLLLYLCPALLICLYKHYSSLRRIIK"
ORIGIN
        1 accgcccaat ctggttcagt cttttcatga actggagagg gtgaaccgta ccgattggtt
       61 ttgtacttcc gacccggtag gtaagaaact tggttccggt ggtggaacat cctggttgct
      121 tgaagaatgt tataatgaat attcagatgg tgctactttt ggagagtggc ttgaaaaaga
      181 aaaaagaatt cttcttcatg cgggtgggca aagccgtcgt ttacccggct atgcaccttc
      241 tggaaagatt ctcactccgg ttcctgtgtt ccggtgggag agagggcaac atctgggaca
      301 aaatctgctt tctctgcaac ttcccctata tgaaaaaatc atgtctttgg ctccggataa
      361 actccataca ctgattgcga gtggtgatgt ctatattcgt tcggagaaac ctttgcagag
      421 tattcccgaa gcggatgtgg tttgttatgg actgtgggta gatccgtctc tggctaccca
      481 tcatggcgtg tttgcttccg atcgcaaaca tcccgaacaa ctcgacttta tgcttcagaa
      541 gccttcgttg gcagaattgg aatctttatc gaagacccat ttgttcctga tggacatcgg
      601 tatatggctt ttgagtgacc gtgccgtaga aatcttgatg aaacgttctc ataaagaaag
      661 ctctgaagaa ctaaagtatt atgatcttta ttccgatttt ggattagctt tgggaactca
      721 tccccgtatt gaagacgaag aggtcaatac gctatccgtt gctattctgc ctttgccggg
      781 aggagagttc tatcattacg ggaccagtaa agaactgatt tcttcaactc tttccgtaca
      841 gaataaggtt tacgatcagc gtcgtatcat gcaccgtaaa gtaaagccca atccggctat
      901 gtttgtccaa aatgctgtag tgcggatacc tctttgtgcc gagaatgctg atttatggat
      961 cgagaacagt catatcggac caaagtggaa gattgcttca cgacatatta ttaccggggt
     1021 tccggaaaat gactggtcgt tggctgtgcc tgccggagtg tgtgtagatg tggttccgat
     1081 gggtgataag ggctttgttg cccgtccata cggtctggac gatgttttca aaggagattt
     1141 gagagattcc aaaacaaccc tgacgggtat tccttttggt gaatggatgt ccaaacgcgg
     1201 tttgtcatat acagatttga aaggacgtac ggacgattta caggcagctt ccgtattccc
     1261 tatggttaat tctgtagaag agttgggatt ggtgttgagg tggatgttgt ccgaacccga
     1321 actggaggaa ggaaagaata tctggttacg ttccgaacat ttttctgcgg acgaaatttc
     1381 agcaggtgcc aatctgaagc gtttgtatgc acaacgtgaa gagttcagaa aaggaaactg
     1441 gaaagcattg gccgttaatc atgaaaaaag tgttttctat caacttgatt tggccgatgc
     1501 agctgaagat tttgtacgtc ttggtttgga tatgcctgaa ttattgcctg aggatgctct
     1561 gcagatgtca cgcatccata accggatgtt acgtgcgcgt attttgaaat tagacgggaa
     1621 agattatcgt ccggaagaac aggctgcttt tgatttgctt cgtgacggct tgctggacgg
     1681 gatcagtaat cgtaagagta ccccaaaatt ggatgtatat tccgatcaga ttgtttgggg
     1741 acgtagcccc gtgcgcatcg atatggcagg tggatggacc gatactcctc cttattcact
     1801 ttattcggga ggaaatgtgg tgaatctggc tattgagttg aacggacaac ctcccttaca
     1861 ggtctatgtg aagccgtgcg aagacttcca tatcgtcctg cgttctatcg atatgggtgc
     1921 tatggaaata gtatctacgt ttgatgaatt gcaagattat aagaagatcg gttcaccttt
     1981 ctctattccg aaagccgctc tgtcattggc aggctttgca cctgcgtttt ctgctgtatc
     2041 ttatgcttca ttagaggaac agcttaaaga tttcggtgca ggtattgaag tgactttatt
     2101 ggctgctatt cctgccggtt ccggtttggg caccagttcc attctggctt ctaccgtact
     2161 tggtgccatt aacgatttct gtggtttagc ctgggataaa aatgagattt gtcaacgtac
     2221 tcttgtcctt gaacaattgc tgactaccgg cggtggatgg caggatcagt atggaggtgt
     2281 gttgcagggt gtgaagcttc ttcagaccga ggccggcttt gctcaaagtc cattggtgcg
     2341 ttggctaccc gatcatttat ttacgcatcc tgaatacaaa gactgtcact tgctttatta
     2401 taccggtata actcgtacgg caaaagggat cttggcagaa atagtcagtt ccatgttcct
     2461 caattcatcg ttgcatctca atttactctc ggaaatgaag gcgcatgcat tggatatgaa
     2521 tgaagctata cagcgtggaa gttttgttga gtttggccgt ttggtaggaa aaacctggga
     2581 acaaaacaaa gcattggata gcggaacaaa tcctccggct gtggaggcaa ttatcgatct
     2641 gataaaagat tataccttgg gatataaatt gccgggagcc ggtggtggcg ggtacttata
     2701 tatggtagcg aaagatccgc aagctgctgt tcgtattcgt aagatactga cagaaaacgc
     2761 tccgaatccg cgggcacgtt ttgtcgaaat gacgttatct gataagggat tccaagtatc
     2821 acgatcataa aaatagtatt ggttgacgag aggtaaggat tttatctctc gtcgacttct
     2881 ttttccattc ctcattaagt ttgcctcttc tgttattctg atagtaaaat agagattctg
     2941 atatctttaa gtctgctttt ttcttgtttt aaaaaccttg ttgtcttgag aaagtgatga
     3001 aatagcaaat gatggagcag taacttgcct ttaattcgtt tcttcatacg tgtactcttc
     3061 atacgaagtt aacttcgtct ttgcaaaaca ttaacttctt gtgaagaaga agttagttat
     3121 aagaaaatac gaagttaact tcatatagtt acgaaattca ttttcattga aaatcctcct
     3181 actttttgcc tggcggtttc atttattgaa caaaaactat agaattcttt tctgtagcat
     3241 aggtcaatat gaatcattcc tgaatgttat tttggaggta taggatgcct tttccgttgc
     3301 ttactgattg aaattagtgc atgtttatcg atcttttgac tggtgatctg atttatctgg
     3361 tggagatatg atattggtga aaatagaatc ccggtgtttt ttataacaac ttagtcagtg
     3421 gtccgtaaat aagggattcc tgaggctact caaaatacaa tgtgacagaa tgcttttggg
     3481 agtatatagt ttctaaacct ttatagatag aataatgaag agtttatctt attatgtaat
     3541 ttgtttataa tcagtatatt gtgtggcaaa tgcgaaaagg ataaaaaggg tgaattcttt
     3601 tgtaattaac tgatagtcag tagtgaatgt gtttcaaaag acgttcgttt aatagcacaa
     3661 aggtataaac taaattttga tgtgcaaaat atttttagat gaaaaactaa atagacttct
     3721 ttatgtactg attatcagat aataatctgg taataaaaac agctttttac ttattttgta
     3781 tgtgggcttt tatctccata attgatgttt caaaagacga acgttttttg aaacatcaat
     3841 tgatcgaatc cgttcgtttc cacctaaaat aagtcataaa aaatcttgca gtttggctga
     3901 gaaaaagagt ctcacccaac tgcgaagcat acccggactt aagtaaatca cttaggaata
     3961 ttccttctaa atgtctcaac aacaagaata ttggttcgct gcccgtaccc gtaaggatca
     4021 ggagcttact actcgtgacg cattagagaa aataggtgtc gagtattttt tgccgaccca
     4081 atttgtcatt cgtcaattga aatatcgccg gcgtcgtgta gaagttcctg tcattcgtaa
     4141 tcttattttt gtacatgcta ccaaagagtt tgcttgtgct attgccaatg aatacggggt
     4201 gcgtcttttc tatatgcgtg attttgacac taagagtatg cttattgttc ccgataagca
     4261 gatgaaagat tttatgtttg tcatgaatct cgatcctgct gctgttatcc tcaacgatga
     4321 ttgtttcgca gttggcacca aagtacaagt catcaaggga gatttttgtg gagttgaagg
     4381 tgaactggcc agtctttcta atcgtactta tgtcactatc cgaattcgtg gcgttttatc
     4441 tgccagtgtc aaggttccta aaagctacct tcgcattctc gcaccgtaat cagtaatatt
     4501 ttatcatata aaatgaatac tcttatgacc cagattcatg agctgcaaca tgtggctcac
     4561 gaattattgt atttgggtgc tgacggttct cctatctata ccgacagttt ccgtcaatta
     4621 aacactgaag tgcttcaaaa atctgatgct ttgtttgctt tgaaaggaga aaatccggaa
     4681 gaagaagcac gactttgcct ggctctcttg atgggctaca atgcaacaat ctatgattat
     4741 ggcgacaagg agtctaagaa acaggttatt ctggatcgtt ccttgcttgt gttagagtct
     4801 ctcccgtctt ctttgctcaa gtgtcagctt ttgacatatt gttatggaga agtttttgaa
     4861 gaagagttgg caaaggaagc tcatgcaatt atagatggtt ggaaagatcg agaattgtta
     4921 gaagaagaaa gagaaatagt tgaaaatttg aggattttgg aagaacctcc atatctgttt
     4981 agtaataaat cttgttagaa atgaaaaaga aagtatatgt tgggatgagt gctgatatta
     5041 ttcatccagg gcatttgaat attattcatg aagcacaaaa actagggaat gtgactgtag
     5101 gtgttttaac agatgctgct atagccagtt ataaacgttt accttattta acttatgaac
     5161 aacgttcctt aatagtacaa aatctaaaag gtgttgatga agttattcca caaactacct
     5221 tagattatat tcctaatctt gaattgctaa aacctgattt tgttgttcat ggagatgatt
     5281 ggaaagaagg cgttcagaag gaaacaagac aacgggttat tgaaactctt tctaaatggg
     5341 gcggacaagt tattgatata ccttatacac aaggtatatc ctcaacaaaa ctcaattcaa
     5401 agcttaaaga aatagggaca actcctgaag tgcgtttgaa aagattaaaa cgtttgattg
     5461 aagctaagtc cattgttcgt atttgtgaat cacatagtgg attaacgggg ttaatcatag
     5521 aaaatacgtc tgttgaggta aatggtatga agcgtgaatt tgatggaatg tggtctagta
     5581 gcttaactga ttcaacatca aaggggaagc ctgatattga agctgtagat ttgacgaccc
     5641 gtttacatga tttaaatgat gctttggaat gtacaacgaa acctgttatt tttgatggtg
     5701 atacaggagg aaaaattgaa cattttgttt ttacagttcg tacgttagaa cgtttgggta
     5761 tttctgctat aataattgaa gataaagttg gattgaaaaa gaattcttta tttggaactg
     5821 atgttattca gacacaagat acaattgagg gtttttgcga taaaatatca gcaggaaaac
     5881 gtgctcaaat aacggatgac tttatgatta ttgccagaat tgaaagtttt attgctggta
     5941 aaggtttaga tgatgctatg aaaagagcat tagcttatat tgaggcggga gctgatggta
     6001 taatgattca cagtaaagat aaatcaggtg aagatattag acttttttgt aaggcgttac
     6061 gagaggttaa tcaatcaatt cctatagtag tagttccgac aacttataat catataacag
     6121 atgaagagtt gtctacatgg ggtataaatg tggtcattta tgcaaaccat atgttacgta
     6181 gtgcttatcc tgctatgcta aatactgcga aatctatatt attacatgcc cgttcatatg
     6241 aggcaaatga tttatgtatg ccagtaaaag atatattaga attaatacca ggtacaaaat
     6301 agttttttta tgatttctcc agaacttttc attaactctc ttgtacaaaa tgaacttaat
     6361 ttttttacag gggtaccaga ctcattattg aaacatattt gtgcctatat aactgatcat
     6421 atagcttcaa atagtcatat agttgctgcc aatgagggag cagcgattgg tttggctgtt
     6481 ggttatcatt tggcaactaa taaaattccg gttgtatata tgcaaaattc cggtattggt
     6541 aattctatta atcctttatt atctttagta gacaaggagg tgtataatat tcctttatta
     6601 ttagtcggtt ggagaggtga gcctggtgta aaggatgaac ctcaacatat aaaacaaggt
     6661 aaggtaacta ttcctttgtt tgattctatg cgaataaaga accagatact ttccaaagat
     6721 aaatctgatt tcttacaaca actaaacgta gcattagaat atataagaga gacaaatgag
     6781 ccttttgttt ttataattca gaaagaaaca ttcagtgatt ataaactgca aactccaaat
     6841 aataatgctt tgttattgga tagagaaact gctattaaga ttattgtttc ttctatttct
     6901 aagaatgata tagtcgtttc tactacagga atgatatctc gtgagctatt tgaatatagg
     6961 gataacatgg gcgaatctca tgaaaaggac tttttaacag tcggttctat ggggcatgcc
     7021 tctcaaatag ctttgggtat tgcattacaa aaaaaggcta gaactgtgta ttgttttgat
     7081 ggtgatggtg ctgttttaat gcatatggga ggactaacaa ccattggatc aataaaaccg
     7141 tctaattaca tccatgtatt atttaataat ggagcgcatg attctgtagg tgggcaacct
     7201 acggttggtt ttgaggtaga ctttacaaag atagctttgg cgtgcggtta taaatatgct
     7261 ttggttgtgg agagtgcttc atctttaaac gaagttctta aaacggtgaa tgaaatgcaa
     7321 ggacctgttt ttttggaggt taaggtaaag aaaggtgctc gaaaagattt aggtcgtcct
     7381 acaataactc caatacaaaa taaagactct tttatggact ttttaaagcg ataatatgaa
     7441 acaacgcata tatattggag aggcctcatt gaataattta gatattattt tgcaggaata
     7501 ttctgcaaag aaggtttttt tggtgagagg gaagaaatca tatgagcttt gtggagcaca
     7561 atcaagatta aactctatat tgaagaaagt aggagttcag atctttgaat tccatgattt
     7621 tgaggaaaat cctaaaatag aagatttaga tagaggactt ttgcaattaa gagtttatca
     7681 tccagatttg atacttgcaa taggaggagg cagtgtattg gatatggcta aattgcttcg
     7741 ttttttttat tcttattctg gaaataaaat aggaagagtt tttgaaaaaa tagaaaatct
     7801 attaccttta attgttatac ctacaactgc gggaactggc agtgaggcta cgagttttgc
     7861 tgtgttatat aagaataaag ttaagtattc tgtttcgcat gaagatatat tacctgaaat
     7921 agcttttatt gatccatatt ttacatataa tatttctcaa tatttgacag cttgcacggg
     7981 gtttgatgca ttggcccagg ctattgaagc ttattggaat ttaaatgcta caaatgaatc
     8041 tgatgttttt gcagtaaaag caataaaatt actttggcct aatttaccat tagcggtaaa
     8101 taatccaaca aaagaggtta gaaacagtat gtctgaaggg gcctattggg ctggatgtgc
     8161 aataaatata acgaagacta cagcacctca tgctttttct tatccattta ctacttatta
     8221 tggctatcca catggacatg cggtggcatt aactttccca ttttttatgg aatataatgt
     8281 aggaagtata ttattaaagc atggtacagt tttcgataaa atgattcgat tgatggaaat
     8341 actcaatata accaatgtaa atgaatgcaa atctttacta tgtgattata tagaaaatat
     8401 cggacttgat ttaaagttgc ctgccaattt tgatcatcga attattcttt caaatataaa
     8461 tgtgcaaagg ttgagtaata accctgtacg aatagatggg gctgtggcta aaacagcttt
     8521 aaatacttta tgtatcaagg atgatgataa agattgatag tgatgaaaat taaaaagtct
     8581 ttagattcct ataaagtaat ttttcaaaat acattttatt tgtcgataat tgaagctata
     8641 cgcttaataa tgccctttat cgctcttcca tatattatta ctactattgg cgcaactaat
     8701 tatgggatta tcattttttc tcaaacgatt gtttcatatt tttcaattgt tattaattgg
     8761 ggattagatg taacttcagt ccgagaagtg tctttaaata gaggtagttt aaaaaaaatg
     8821 agtttaatcg tttctactgt atttactatt aaatttattt tgtttggact ttgcttttct
     8881 attttcatga tatgtttgtt ttttatccct ttctttcaac aatatagaat tatatatctg
     8941 tatgcttttt tgtcatgctt ttctgaggtt attatacctg tgtggttttt tcaaggtatt
     9001 gagaagatga agtatttgac ttatataaga acaacaagta tagttctcta tactatactt
     9061 gtttttactt ttattaaaaa agaaatggac tttacacttt tagccttatt acaatctttg
     9121 gctaatatta ctgcaggtgt attttcatta atattattat taattttttg tagagtcaaa
     9181 tttgtatttc ctactttcag agtgatgaaa gaaacttttt gtaatagtac accgtttttc
     9241 gtttccagag tttcgttttt attgaatacg aatatagcta aaacgatgag tgggttattt
     9301 ctgaatatgc acactgttgc cgcatttgat ttgtctcaga aaattttatc ttttgtgtct
     9361 gttcccatac aaatgctgaa tcaggcgatt tatcctcatg ttgcaaaaaa tccaattaaa
     9421 tcattttctg taaagatgct atatgttata gctgcattat ctttgatttt atctgtttta
     9481 cttttttttc tagcacccta tatcattctt tatttttcag agcaactata tgctgaagct
     9541 ctaattttta taaggatctt gtgtctttat gtattttgtt ttggtattaa tacttattta
     9601 gggactccac ttcttgtcgc ttatggtttt tataagccat ttaacttcag tgtaatatat
     9661 tctactttat ttgtgtgctc tttgtacggg attttatacg tatttaattt attgggtggg
     9721 gagtgctttg ctttagcaat gttcttaaca gagcttttta ttctgatata tagattttat
     9781 tattgtttga aatttaaatt gatataaaaa taatggaaaa gatatctaac tataatactg
     9841 atggtactat gttgcgaaag caacaagaac gtatgttcga aatgttatgt gtaatagatg
     9901 atatttgtgt caagaatgaa attaattatt ggttatctgg tggaactctt ttaggagctg
     9961 ttaggcatgg aggttttata ccatgggatg atgatttaga tattcaactg atgaaagatg
    10021 actataataa attactaggt ttattaaaga cagaacttcc tgaacaatac cagttacaaa
    10081 catctaagac tgatagaaac tatttcgcaa gatatgcgaa agtaagagat gtgaattctt
    10141 tgcttgaaga tagtgattat actttgggat ataaatataa agggatattt atagatattt
    10201 tttctgttga aaaagcaaat aaatttctag taaagatatc tgcttttatg caatggtatc
    10261 tattgatctc tttgttacct atggtacata agaaaactaa aatgcaattg aatctttttt
    10321 cattatggaa taagttttta ggtacttttt attctggatt cagactattt ggtaaattgt
    10381 ttgccaagaa aattaattat tcttatggag tttactatcc tttaaattgt gattatacta
    10441 ctatatttcc attaacaaca attgagtttg aaggacgtat gtttaaagtt ccaggaaatt
    10501 ataatttata tttatgtaat atatatggtg attatatgaa acttcctcca gaggaagaaa
    10561 gagaaaatca taatataaga gtggttcata ttgtttagtt ctcactatat ttatgttaat
    10621 agtaatacta ctgactctaa tcttaatata tatattatat aagatatata aaaaaaagaa
    10681 ggttcatcaa tttttactca tatattttgc tttttctgct tttttgtggg ttatttttcc
    10741 atcgattgtt tctttaatag gagatagata taaacaggaa ttggtagtaa aagaaaatgt
    10801 ttttataact tatgctattt atgaatttct tttttatata atattgttac ttttactcta
    10861 tcgttttcca ttatgtaaac ctttctatta tgggaaatat attcccaata catcctcgtc
    10921 tataaaacga atatggtttg tattaagtct ttttctcatt attaatatta tcaagcagat
    10981 atcttccaat gttacttatt ctgaagtcaa tgattcaact atattggctg aacaggaaac
    11041 taatttattt tcaatttttt caaatttctc tatatgccta tatcttacta taatattatt
    11101 ttacaataaa ctttattcaa aaagaatcat ttttttctct tggctattac tatctcttaa
    11161 tataataacg gttttagctc atggagcaag aatgcaagtt attttttatt tgtttgtttt
    11221 tgtatattat ttattttctt cggcattaaa taaaaaacgt tttttcttat atatgtcttt
    11281 tctgatcgga attatttatt tatgttctta tattcttccg gcagttgcat atataaggtc
    11341 aggaggaaat tttacagttg aggatttgag aaagtcatat gagaattatg gggaagcaaa
    11401 tgcttttgtc cttcaattgc tgattaagtc taatagtata aatactgggg ccattttagt
    11461 tgaggaaaca aaagaaaagc catacttgaa tccatatatt aattcaatat attcattctg
    11521 cccaagtata ctctttcctg gaaaaagacc tttggcaggt agtagtgatg gtacgattga
    11581 tggattccct acaagattag ccgcagaata tataagtggt gattctcgtt tctttaatgt
    11641 gggaatatca acttctgcca cggcactatg gcatggtggt attttatttt atgtgattaa
    11701 tttaattata gttttttttt ggtatcgttt tctgaattca ttaatgtttt atgaaaacta
    11761 ctatgcaaaa cttttagttg tatattttac agttttgggg tattttatac ttcctacggc
    11821 agatgtctta atacgggatt tgcttaaaca gcctttcttt tatgcattct ttatatttat
    11881 ctcgagaggc ggtcttatta aagattgggt tagatctttg aaacgtcata ttgcttagtg
    11941 aaaagatatt ctttgaattt atcatcatga ataatcccat acttttatct attgtaatcc
    12001 ctgtatataa tgttgagtta tatattgaac gttgtctatt aagttgtttg aatcaagatc
    12061 tttcaatatc acaatatgaa atcattttaa tagatgatgg aagcccagat agcagtatcg
    12121 ataagatttc aaaatggtta gatagaaaaa atataacttt gttaactcag cctaatagtg
    12181 gattaagcgt tgcacgaaat aatggattac tacatgcaaa aggtaaatat gtttggtttg
    12241 ttgattccga tgactggatt ttagaaaatt gccttcaaga gattgcaggt tatatggttg
    12301 ctggaattga tattattact ttctgtgctg cagactttat taatgataaa ttttatcgga
    12361 gatttgaata cataacaggt gtaaataaaa aaatcgaagg aagggattta ttaaaaagag
    12421 gaacttgtca acattgtgtg ccattttcta tatatcggaa aagattttta gaacaaaatc
    12481 atttgttctt tttgccaaat atttttcatg aagatacaga attttctcca cgggcatatt
    12541 atttagcgaa tcatgttttt tgtattaata aggtatttta ttatgtgtat cataatccta
    12601 attcaataac aagaacattt aatccgaaaa agtcttttga tttattaatt gtatctcaca
    12661 gcttgtctat attcatgttg gatgttactc ctgagtataa atcttgtttt aataatttga
    12721 tttctttgtc tataaatgct gcaataaatg gcattgttac ggcaaaaagc gagatttcta
    12781 ggtttatagt ggatttaact gctagaggat tgtatcgaaa catgcttaat gccggaaaat
    12841 taaggtataa aatagaagga ttactactct atttatgtcc ggcattgttg atttgtctgt
    12901 ataaacatta ctcttcattg agaagaatta ttaaataatc taataaaaat gttatggtgt
    12961 ttgttaaacc aattaagatt gccgtaatag gtcttggtta tgtcgggcta cctttggccc
    13021 gattgttttc gacaaaatat gaatgtattg gttttgatct gaaccagtct cgtgttgatg
    13081 ctttaaattc cggtcatgat atgactttag aggtttctga tgacttactt cggaaagcga
    13141 tagaaaatgg tttcaaatgt accagtaata ttgacgaaat aagtaattgt aacttttatg
    13201 ttgtagctgt accaacccct gtggatttga ataatcgccc cgatcttaca cctttgattg
    13261 gtgcgagtac tacagtcggg aaagttattt caaaagggga tattgttgtg tatgaatcta
    13321 ctgtatatcc gggagttact gaggaagaat gtcttccggt agtcgaaaag gtgtctgggt
    13381 taacatacaa tgtagatttt tatgcaggtt attcaccaga acgtataaat ccgggtgata
    13441 aagagcatac tgttgaaaag attaagaaag taacttctgg ttcgactcct gagattgctg
    13501 acattgttga ttctgtttat aattcagtgt tggttaacgg tactcataaa gcccctt
//
