LOCUS       c00041_gnlPro..        17558 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EEOGJDHE_76.
ACCESSION   c00041_gnlPro..
VERSION     c00041_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:15:11
            Original ID  :: gnl|Prokka|EEOGJDHE_76
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17558
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17558
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4012:7558](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(4013..7558)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..17558
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17558
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             571..783
                     /locus_tag="ctg41_1"
                     /transl_table=11
                     /translation="MLISLISYAQGLMWTAKAELNMSSMSNVEESKMHPGFYAGIGAGY
                     VIDETRSVRPSLLFTMKGVKQDYKF"
     CDS             799..1575
                     /locus_tag="ctg41_2"
                     /transl_table=11
                     /translation="MKKLFFIMAMSVCAFTAQAQTTSGIRVGLNMTSATGKYNDLMADQ
                     DYNNKSYMGYSIHYFIDVPVIGNFSIQPAVGLSMKGITYEYDKFTTKKSHRLDLDSYKK
                     YDVTESRGTSVTQKHNLGYLDVPILFAYALPLSESFRVQLGVGPYFSYGLFGKFKYESD
                     KYLTVSPDKYGENKHTITKDDYPSFGKNDDADDPKGNINRFDWGIAVQGSIYWKRLFLN
                     VAYQKGLKSANITDEKNEGKDKLALSNLSLGLGFIF"
     CDS             complement(2279..3796)
                     /locus_tag="ctg41_3"
                     /transl_table=11
                     /translation="MNILINLKYTLAVTAGVCSSFAYAQKHPHIILIMTDQQRADAIGC
                     MGNDAVISPNLDALAAEGTLFMNGYSSCPSSTPARAGLLTGLSPWHHGLLGYGKVSPEY
                     KYEMPQMLKDAGYYTFGIGKMHWHPQRIKHGFEGTLLDESGRVEDENFTSDYRQWFQTK
                     APGKNPDATGIGWNDHTASIYKLPENLHPTYWTGEMACELISNYDPTNKPLFLKVSFAR
                     PHSPYDPPQRYLDMYKDALIPDPAIGDWCGKYAKKLNPEETAQDAPYGNFGNEYARNSK
                     RHYYANITFIDEQIGRIIQTLKEKDMYNDALIVFVSDHGDMMGDHYHWRKTYPYEGSTH
                     VPYIVKWPSANHVTPGKTDAPVELRDILPTFLDAADVTIPTDMDGRSLLPLAKGMETNW
                     RKYLDLEHATCYSDDNYWCALTDGKIKYIWRIHTGTEELFDLTQDPQELHNAVNDKKYR
                     KQLTEMRNEMIRHLSERGEEFVKDGRLVVKEKTMLYGPHYPEKENKR"
     CDS             3861..4049
                     /locus_tag="ctg41_4"
                     /transl_table=11
                     /translation="MVMVTVEILEIEVLFCTYVWVTSYILMVEKAIKKGLFHTGTSLFL
                     YACIRDYSPQFIASIRL"
     CDS             complement(4013..7558)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_5"
                     /sec_met_domain="PFOR_II (E-value: 4.9e-19, bitscore: 59.7,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 2.7e-83, bitscore: 270.2,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.9e-31, bitscore: 100.5,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-12, bitscore:
                     38.5, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.2e-12, bitscore: 39.7,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.3e-07, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 4.5e-26, bitscore: 81.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSCRQTGFAMLCEGSVQEVMDMAAVAHLATI
                     KSRVPFVNFFDGFRTSHEIQKIEMLENEDLAGLIDQQALAEFRQRALNPNNPVARGMAE
                     NPDHFFQHRESCNNFYEAVPAIVEEYMNEISKITGRPHGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDYLMSKGEKVGLVSVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGTENAPVIVGGRYGLGSKDTTPAQIIAVFKNLALPMPKNHFTVGIVDD
                     VTFTSLPQEEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNITVYYINATQIAQEIGLGNRTNTILQSAFFRITGVIPV
                     DLAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKQLAVDPAWANLEVEAPAANNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWEQGTAQYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGADFETLKAVGKQFDGMTFRIQVDVLDCLGCGNCADV
                     CPGNPKKGGKALTMKHLESQLSQAANWEYCAKNVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTKNEKGQGPAWANS
                     LFEDFCEFGLGMTLADKKLRARIEAAMKDAIASDTCPAEYKEAFQEWIDGKDDADKSKA
                     AAEKIIPMVEAAKDKCKNCATIAEFKNYLVKKSQWIIGGDGASYDIGYGGLDHVIASGE
                     DVNILVLDTEVYSNTGGQSSKATPLGAIAKFAASGKRVRKKDLGMIATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLVIAYAPCINHGLKAGMGKSQAEEAKAVECGYWHLWR
                     FNPALEEEGKNPFMLDSKEPKWEGFQDFLKNEVRFASVMKQYPAEAADLFAACEEMAKK
                     RYASYKRMEAMNWGE"
     CDS             complement(7601..8581)
                     /locus_tag="ctg41_6"
                     /transl_table=11
                     /translation="MNNFYFSKYTLVEFAAEFVKRGGKVLLIDQVFKYPEWSHDLRACY
                     EMFPTLKIIFTGSSVMRLKEENPELSGIAKVYYLRGFSFREYLNLQSGNCFRAYTLQEI
                     LENHEQIAKTILRNVKPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMIEVDILLIK
                     QIELKYLSKIKKLLYLLAVDGPVAPNVSQLATEIQTSRATVMNYIKYLADARLINMVYP
                     KGEEFPKKPSKLMMHNTNLMYSIYPVKVEEQDVLDTFFMNTLYKDHKLYKGDKGTSFMV
                     DNGLHFRICAEGCKFKNNPNVYYALHKLELGHGNMIPLWLFGFLY"
     CDS             8600..10093
                     /locus_tag="ctg41_7"
                     /transl_table=11
                     /translation="VIRSELFFCILQEESRFPYATSTLDADQSVVPVYFVHQVPANRSI
                     CMFHQITVCSVKGFHGCFFIGCKYSNTNSNCKLEIAKYYFFSTKRRTREMVCTLKHLSL
                     CPEMEALYLFNPENDMALACGDPYYMAPASARRMAAELSVLPAWYAEQGGTVWLDSALR
                     MKTMERQSFLPLSVNWTSEFLPIYNKVIPWGWNPSLVRRLQEAGFPDTAYPSVERMKRI
                     RQISGRQTAVKVLRRLCRHIGGNIPTLGEAFVLSSTEEVKAFVLSHPRALLKAPWSGSG
                     RGIQYVSGSFTIPLEGWVRHILTTQHEVIGEPFYDKLLDFAMEFFADEWEQVHFIGYSL
                     FETDKRGVYKENLLAADRVIEARISTYVSAEILHQVGRMLQVELAEVIKGSYEGYLGVD
                     MMICRTQNGGYAIHPCVEINLRMNMGVVARLIYDNYVCDGVQGRYVIEYYAKPGEAWHS
                     HLALQEKHPLYLENGKVKSGYLSLTPVENNTSYQAYILI"
     CDS             complement(10132..11514)
                     /locus_tag="ctg41_8"
                     /transl_table=11
                     /translation="MKEMMKHTLLYIAVSGMTLLTSCQLGKHYTRPDLHLPQQLDTLRQ
                     QDTLSIADMQWWEIYTDTTLQSLIEKTLDNNKDMKIAAARVKELAAMKRIDFANLFPQL
                     NGSAYAQKEGSNYGGDNYKNDPEQGGKLTVTWELDLWGNLRWAKDKSIAQFLGSIEAQR
                     ALKMSIVSEVAQAYFELVALDNELNIVRQTLYARKEGVRLAKLRFEGGLTSETSYQQAQ
                     VEYARTATLVPELERKISLKENDIAFLAGEYPHRIQRSILPEEVKLPETLPVGLPSTLL
                     ERRPDVREAEQKLIAANASVGIAYTNIFPRLSLTAQYGVESEEFSDFFKSPIHYISGNL
                     LTPLFAMGKYRATLKAKKAAYEQECYSYEKSVLTAFKEARNAIVDFNKIKDIYESRLQL
                     ERSSKATMELAQLQYINGVIGYLDVLDAQRSYFDAQIGLSNAIRDKQITLVKLYKALGG
                     GW"
     CDS             complement(11527..14541)
                     /gene_functions="resistance (resist) RND_efflux (Score:
                     957.5; E-value: 6e-290)"
                     /gene_kind="resistance"
                     /locus_tag="ctg41_9"
                     /transl_table=11
                     /translation="MLPIDQYPQITPPVVKISASYPGASALTVSQAVATPIEQELNGTP
                     GMLYMESNSSNSGGFSATVTFDISADPDLAAVEIQNRIKLAESRLPAEVIQNGISVEKQ
                     AASQLLTLCLTSTDPKFDEIYLSNFATLNVLDLIRRIPGVGRVSNIGSRYYAMQIWVQP
                     DKLANFGLTVADLQNALKDQNRESAAGVLGQQPVQGLDVTIPITTQGRLSTVSQFEEIV
                     VRANADGSIIRLRDVARISLEAQSYNTESAINKENAAVLAIYMLPGANAMEVAKSVKEA
                     MEEISKNFPEGMSYEIPFDMTTYISESIHEVYKTLFEALILVIIVVYLSLQSWRATVIP
                     LVAVPISLIGTFGFMLIFGFSLNILTLLGLVLAIGIVVDDAIVVVENVERIMEEEKLSP
                     YQATKKAMEGLAGAIIATSLVLAAVFVPVSFLGGITGQLYRQFTVTIVVSVLLSTVVAL
                     TLSPVMCSLILKPEDPNKKKNIVFRRINEWLAIGNHKYVGLIKHIVKHPRRVLSTFGMV
                     LIAILLIHRIIPTSFLPIEDQGYFKIELELPEGATLERTRIVTERAVEYLMKNPAVEYV
                     QSVAGSSPRVGTSQARSELTVILKPWEERDSQTIDNIMAQVKKDMSQYPECKVYLSTPP
                     VIPGLGSSGGFEMQLEARGDATFENLVQATDTLMYYASKRKELSGLSSALQADIPQLYF
                     DVDRDKVKFSGVPLADVFSTMKAYTGSVYVNDFNMFNRIYRVYIQAEAPYREHKENINL
                     FFVRGTDNAMIPLTSLGTTSYTTGPGSIKRFNMFNSSVILGEAADGYSSGQAMEIIEQI
                     AREHLPENIGVEWSGLSFQEKQAGGQTGMVLALVFMFVFLFLAALYESWMVPVAVLLSL
                     PVAALGAYLGVWGCGLENDVYFQIGLVMLVGLAAKNAILIVEFAKEQVDKGVDVVQAAL
                     HASQLRFRPILMTSLAFILGMLPMVIASGPGSASRQAIGTGVFFGMIFAVTVGILLVPF
                     FFVLIYKMKAKMKQK"
     CDS             complement(14695..15894)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_10"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 1.3e-08,
                     bitscore: 25.7, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLFFTHKEIALKKKRTALVVIGIGLVIGIYLIVSHRPAKMPELP
                     VVAIAPATQDDVEIYGEYVGRVRAQQFVEVRARVEGYLEQMLFAEGTYVTKNQVLFVIN
                     QDQYRAKADKARAQLKKDEAQAQKAKRDLERIRPLYEQNAASQLDLDNATAAYETAEAS
                     VAMSSADLDQAELELGYTIVRSPLAGHISERHVDLGTLVGPSGKSLLATVVKSDTVLVD
                     FSMTALDYLKSKERNVNLGQKDSTRSWQPNVSITLADNTIYPYKGLVDFAEPQVDPRTG
                     TFSVRAEMPNPERILLPGQFTKVKLLLDVREKATVVPLKSVIIEKGGAYIYVMRKDSTV
                     ERRFIELGPEFQNQVVVERGLAPGEDIVIEGYHKLNPGMKVKVSPAVEDKKTEEKDTIG
                     "
ORIGIN
        1 atatcctcat caattctttg aggaaaaaga acggtttggt tgggattgta agaacgaaaa
       61 tgtatctttg tcatagtgaa attcttatta cctaaagata caaaatcttt aggtaataac
      121 aaagccctag cttgtgaaag tcggggcttt gtgcgtaaaa aacagaaggt gtgcattttg
      181 acacaccttc agtgaaacat aaaacaaaca ggcgtttatt cttcggaaat gaacgcctgt
      241 ttgtttatgt tttaaatggt tctatactgc cagcttggag aggtgtgaaa agtagaactg
      301 tttttttgat ggctcttcca atttcatatc atatagagct ggaatgtgaa gcttaattta
      361 caaattttca agcttgtctt attggcataa tttatttatt gtatatatag tcgttaattt
      421 tagctgcttg gtatctgctt tagtgtgttt agtgtaaatc ttgacaaatg atggtttttt
      481 gaatataaaa gttgcaatac atttgcaaat gtaaacttat agagtcaatt gttacgaagt
      541 atggaaaaga caattattgc agcactttta atgctgattt cgttaatatc gtatgcacag
      601 ggtttaatgt ggactgcgaa ggctgaactc aatatgagca gcatgtctaa cgtagaggaa
      661 tctaaaatgc atccaggttt ctatgcagga ataggagctg ggtatgttat tgatgaaact
      721 cggtctgtcc gtccttcttt attgttcact atgaaaggag tgaaacaaga ttacaaattt
      781 taataaaaat actgcattat gaagaaactg ttttttatca tggctatgtc cgtatgtgca
      841 ttcacggcac aagcacaaac tacttccggt attcgtgtgg ggttaaatat gaccagtgct
      901 acagggaagt ataatgatct tatggcagat caagattata ataataaaag ctatatgggt
      961 tacagtatcc attattttat agatgttcct gtgattggaa acttcagtat tcagcctgct
     1021 gttggacttt ctatgaaagg tatcacttat gagtacgata aatttaccac taaaaagtcg
     1081 catcggctcg atttggattc ttataagaaa tatgatgtga cggaatctcg cggcactagt
     1141 gtcactcaaa aacataatct gggatatttg gacgttccta ttttatttgc ttatgcttta
     1201 cctttgtcag aatcgtttag ggttcagttg ggagtggggc cttacttctc ttatgggttg
     1261 tttggtaagt ttaaatatga gtcggataaa tatttgacag tatcccccga caaatatgga
     1321 gaaaataaac ataccataac caaagatgat tatccctcct ttggcaagaa tgatgatgcg
     1381 gacgatccta aaggtaatat taaccgtttt gattggggaa ttgccgtaca gggcagcatt
     1441 tattggaaac gcttgttttt gaatgtcgct tatcaaaaag gtttgaaatc ggctaatatt
     1501 actgacgaga agaatgaagg gaaagataaa ttggcccttt ccaatttgtc gttagggtta
     1561 ggctttatat tttaagttgt gaacaggctg aggaactgct ggaaaataga agaatagaga
     1621 ggcatcagaa atttgatgaa acttgtgcac cctttcttgc cgaaatgaag aatctgtcgg
     1681 atgtaaatag aggttcattt ggaaacgtat gtgtagaaac ccgtttccgg tcactgttcc
     1741 gtatcgttcc gaaagtcttt attcttttcg gaaaagacaa ggacgtttac aaaaaagatg
     1801 aagacgtctg ataaaaagaa caagacgttt cattccaaag atctatatct ttcaatcttt
     1861 agtttaagtc tttccggctc taccggttta tccttctcct ccgaaaggga aggatgctgg
     1921 atgtaacggc aaaacttggt acaggatttc gtggaacttg ctgcaagatc cgacagaact
     1981 tgtatcaaga ttctgaatac tttggcaagg aaagtcgcag tttcgaggct gcacaagctt
     2041 accgtgttta ttgcacaagc ctgctttgtc caccggacag ggcaggcttg taccatggaa
     2101 caaggtggat aaagtggtgg ctgcaggcat ttttcttgca taaaataatg tattgccatc
     2161 acctctctaa ctccctattc ataggaagtt agagaggtga tggcagtggc aacagaatta
     2221 taaaactctg ttgtaggaaa gtggggcaat tggaaacgac tcctctgtac aacacacgtt
     2281 atcttttatt ttctttttcc ggataatgag gtccataaag catggtcttc tccttgacca
     2341 ccaatcggcc gtccttcacg aactcttcac cgcgttcact taaatggcga atcatttcat
     2401 tacgcatttc cgtcagctgt ttcctgtatt ttttgtcatt gacggcattg tgcaattcct
     2461 gagggtcttg ggtcaagtcg aataactctt cggtaccggt atggatacgc catatatatt
     2521 ttattttgcc gtcagtcagt gcacaccaat agttatcatc actgtaacag gtggcatgct
     2581 ccagatccag atacttgcgc cagtttgttt ccatgccttt ggcaagcggt aacaaggaac
     2641 ggccgtccat gtcagtgggg atggtcacat cggctgcatc gaggaaagtg ggaagaatat
     2701 cacgcaactc tacgggagcg tctgtttttc ccggtgtaac gtggttggca gaaggccatt
     2761 tcacgatgta tggcacatga gtggagccct cgtatggata ggtctttctc cagtgataat
     2821 ggtcacccat catatcgcca tgatcggaaa cgaaaacgat taatgcgtca ttatacatat
     2881 ccttttcttt caatgtttgg ataattctgc ctatctgttc gtcaatgaaa gtgatgttgg
     2941 cataataatg acgtttggaa ttgcgtgcat attcattgcc aaaattaccg tatggagcgt
     3001 cttgtgccgt ttcttcagga tttagtttct tggcgtattt gccacaccag tctccgatgg
     3061 caggatcggg tattagggca tccttataca tgtccagata tctttgtggt ggatcatacg
     3121 gactgtgcgg acgggcaaaa gaaactttca gaaataacgg tttgttggtc ggatcgtagt
     3181 tgctgataag ttcacaggcc atttctcctg tccaataggt aggatggagg ttttcgggca
     3241 atttatagat acttgccgta tggtcgttcc agcctatgcc ggtggcgtca ggattctttc
     3301 cgggggcttt tgtttggaac cattggcggt aatcactggt gaaattctcg tcctccacgc
     3361 gtccgctttc atctagcaga gtgccttcga aaccatgttt tatccgttgg ggatgccagt
     3421 gcattttccc gattccaaaa gtataataac cagcatcttt tagcatctgt ggcatttcgt
     3481 atttatattc gggagatact tttccatatc ccaacaagcc atgatgccaa ggagaaagtc
     3541 cggtcagcag acctgcacgt gccggagtgc tgcttggaca agaagaataa ccattcataa
     3601 ataatgttcc ctcggcagct agtgcgtcca ggttagggga gataaccgca tcgtttccca
     3661 tacagcctat ggcatcagct cgctgttggt cggtcattat cagtatgata tgaggatgtt
     3721 tttgtgcgta tgcaaaagag gagcacactc cggctgtgac agccaatgtg tatttcaggt
     3781 tgattagaat attcatgttt ataggttttt cataatgtta tgtgcaaagg taggaaattt
     3841 ttggtaacct taagccataa atggtgatgg ttacagtaga aatacttgaa attgaagtct
     3901 tgttttgtac atacgtatgg gtgacctcat atatactaat ggtagaaaag gctataaaaa
     3961 aaggcttgtt ccatacagga acaagccttt ttttatatgc atgtatcaga gattattcac
     4021 cccaattcat tgcttccata cgtttgtaag aagcataacg tttcttggcc atttcttcgc
     4081 aagcagcaaa tagatctgct gcttcagcag gatactgttt cattacagaa gcaaaacgaa
     4141 cttcgttctt caagaaatcc tggaaacctt cccatttcgg ttctttagag tcaagcatga
     4201 atggattctt gccttcttct tccaaagcgg ggttgaaacg ccacaagtgc cagtaaccgc
     4261 attctacagc cttagcctct tcagcctggc tcttacccat acctgccttc aaaccgtggt
     4321 tgatacacgg agcgtaagcg ataaccaatg acggaccggg gtaagcttct gcttcacgga
     4381 tagctttcaa agtctgagct tggtcagcac ccatagcaat ctgggcaaca tatacataac
     4441 cgtaagtagt agcgatcata ccaaggtctt tcttacgtac acgcttacct gaagcggcaa
     4501 acttagcgat agcacccagc ggagtagcct tagatgactg accaccggta ttagagtaaa
     4561 cttcagtatc caataccaaa atatttacat cttcaccgga agcaatcacg tggtccaaac
     4621 caccgtaacc gatatcgtaa gaagcaccgt ccccaccgat aatccattgg ctcttcttaa
     4681 ccaaatagtt cttgaattct gcaatggtag cgcagttctt acatttatct ttagcagctt
     4741 ccaccattgg aatgatcttt tcggcagcag ctttgctctt gtctgcatcg tccttaccgt
     4801 caatccattc ctggaatgct tctttgtatt ctgccggaca agtatcactg gcgatagcat
     4861 ccttcatagc agcttcgata cgtgcacgaa gtttcttgtc agccaaagtc atacctaaac
     4921 cgaattcgca gaaatcttcg aacaatgagt tagcccaagc aggaccttga cccttttcgt
     4981 tcttagtata aggagttgaa ggaacagaac cggagtagat agaagaacat ccggtagcgt
     5041 tagcaaccat ttcacggtca ccgaataact gggaaatcag tttcacatac ggagtttcac
     5101 cacaacctga acaagctcca gagaattcaa acaacggagt agcgaactga gagttcttca
     5161 cattggcttt gatatctacc aaatgttgtt tgctcttcac gttcttagcg cagtattccc
     5221 aattggctgc ttgagacaac tggctttcca aatgtttcat tgtaagagcc ttgcctccct
     5281 tcttcggatt gcccggacaa acatcggcac agttaccaca acccagacag tcaagcacgt
     5341 caacctgaat acggaatgtc attccgtcaa attgtttacc tacagctttc aatgtttcga
     5401 agtctgcacc cttctgttct tcagcgtcaa gtacgaacgg acggatggaa gcatgaggac
     5461 aaacatatgc acacttgtta cactggatac agttttcagc attccattca ggtacgaatg
     5521 cagctacacc acgtttttcg tattgagcag taccttgttc ccaagtaccg tcttcgatgc
     5581 ctttgaatgc agataccggc aacaagtcac catcctgagc gttgatagga cgaactactt
     5641 cgttgatgaa tgcagggtca ttgttagcag caggagcttc aacttccaga ttagcccaag
     5701 ccggatcaac agccaattgt ttgtattcac caccacggtc tacggcagca tagttcttgt
     5761 tcaccacgtc ttcacccttc ttgccataag acttaacgat gaatttcttc atctgttcta
     5821 cagccaagtc aacaggaata acgcctgtga tacggaagaa tgctgattgc aggatggtat
     5881 tggtacggtt gcccaaaccg atttcctgag caatctgagt tgcattgatg tagtaaacag
     5941 tgatattgtt ctgagcgaag tatttcttca ctttgttagg caggttcttt gccagttctt
     6001 caccttccca gatagtgttc agcaagaaag aaccgttctt acgcaaacca cgggttacat
     6061 cgtacatgtg cagataagcc tgtacgtggc aagctacgaa gttcggagta tttaccaagt
     6121 aagtagaacg gataggagta tcaccgaaac ggaggtgaga gcaagtgaaa ccacctgatt
     6181 tcttagagtc gtatgagaaa taagcctggc agtgcttgtc ggtgttgtca ccaataatct
     6241 tcacagagtt cttgttggca cctacagtac catcagcacc taatccgtag aatttagctt
     6301 cgaacatgcc ttcaccgccc aatgcgattt cttcttcctg gggaagagaa gtgaaagtta
     6361 catcgtctac gatacccaca gtgaagtggt ttttcggcat tggcagagcc aaattcttga
     6421 atacagcgat gatttgagca ggagtagtgt ctttagaacc taaaccgtaa cgtccaccta
     6481 cgataaccgg ggcgttttct gttccataga agcagtcttt aacatccaga tacaaaggtt
     6541 caccgtttgc tcccggttct ttagtacggt caagaactgc gatagtcttg gcagtcttag
     6601 gtacagcagc caagaaatgt ttagcagaga acggacggta taagtgtaca gaaaccaaac
     6661 ctactttttc acctttgctc atcaagtagt cgatagcttc gcgggcagct tctgtaacag
     6721 aacccattgc gataattacg cgttcagcgt cttcagcacc atagtaatcg aacaaaccat
     6781 gaggacggcc tgtgattttg ctgatttcgt tcatgtattc ttctacgata gccggaacag
     6841 cttcatagaa gttattgcaa gattctctgt gctggaagaa gtgatcgggg ttttcagcca
     6901 taccgcgtgc aacagggttg ttaggattca acgcgcgttg acggaattct gccaaagcct
     6961 gttgatcaat cagacctgcc agatcttcat tctccagcat ttcaattttt tggatttcgt
     7021 gagaagtacg gaaaccatcg aagaagttga cgaatggcac gcgagatttg atagtagcaa
     7081 gatgggctac agcagccata tccataactt cttgtacaga accttcgcac aacatggcga
     7141 aacctgtttg gcggcaagac atgacgtcct gatggtcacc aaagatacac aatgcgtgtg
     7201 aagccaatgt acgagccgat acgtggaata cgcaaggcag gaattcaccg gcaattttgt
     7261 acatgttagg gatcattagc aacagaccct gagatgcagt gtaagtggta gtcaacgcac
     7321 ctgcctgaag agaaccatga acagcacctg ctgcaccgcc ttctgactgc atttcttgta
     7381 ccaaaactgt ttcgccgaag atgtttttac gacctgcggc agcccattcg tctacgtatt
     7441 cagccatagt agacgacgga gtgatgggat agatagcagc tacttcagaa aacatatacg
     7501 agatatgtgc tgctgcctgg ttaccatcac aagtgatgaa ttttttttgt ttagtcatac
     7561 aattactaat tattaggtaa taaaatctat tctctatctc ttaatataaa aagccgaaaa
     7621 gccataatgg gatcatattt ccgtgtccta attccaattt gtgtagggca taatacacgt
     7681 ttggattatt tttgaacttg cacccttctg cgcaaatacg gaaatgcagt ccgttgtcta
     7741 ccataaatga agtgccttta tcgcctttat atagtttatg gtccttatac agggtattca
     7801 tgaaaaatgt atccagaaca tcctgttctt cgacctttac cggataaatg gagtacatca
     7861 ggttggtgtt gtgcatcatc agtttggaag gtttcttggg aaattcctct cccttgggat
     7921 aaaccatatt gataagacgc gcatctgcca gatacttaat gtaattcatc accgtggcac
     7981 gtgaagtttg aatctccgtg gccagctggc tgacgttcgg agcaacgggt ccgtccacag
     8041 ctagcaaata tagtaatttt tttatctttg aaagatattt cagctcaatt tgtttgataa
     8101 gaagtatatc tacttctatc atcatattca tggtttttag cagattctcc gaaaagttac
     8161 gtttttccag gaagaatggg tagaaaccgt gatgcagata gtcttgaaaa taatccaacg
     8221 gcttcacatt gcgcaggatg gttttcgcta tctgttcgtg attctccaaa atttcttgta
     8281 aggtataggc acggaaacaa ttaccgcttt gcagattcag atattcgcgg aatgagaaac
     8341 ctctcaggta gtataccttg gcaatgccgc tcagttctgg attttcttct ttcaatcgca
     8401 tcacggatga tccggtgaat ataatcttca gagtaggaaa catttcatag caagcacgca
     8461 ggtcgtggct ccattcggga tacttgaaca cttggtctat caacaaaact tttcctcctc
     8521 gttttacgaa ttctgcggca aactccacta acgtatattt agagaagtaa aagttattca
     8581 tgttgatgaa cagacatgag tgatccgttc cgaacttttc ttttgcatat tgcaggagga
     8641 aagtcgtttt ccctacgcca cgagtaccct tgatgccgat cagtctgtcg ttccagtcta
     8701 tttcgtccat caagtcccgg cgaacaggag catttgtatg ttccaccaga taactgtgtg
     8761 ttctgtaaaa ggtttccatg gttgcttttt tatcggttgc aaatatagca atactaattc
     8821 aaattgcaaa ctggagatag caaaatatta ttttttttca actaaaagac gaacaagaga
     8881 aatggtttgt actctaaaac atttatcttt gtgtccggaa atggaagcgc tttatttatt
     8941 caatccggaa aatgatatgg cattggcttg tggtgatcct tattatatgg cacctgccag
     9001 tgcccggcga atggcggccg agctgtccgt gttgcctgca tggtatgcag aacagggagg
     9061 aactgtatgg ctggattctg ctctgcgtat gaaaacaatg gaaagacaat cttttttgcc
     9121 gctttcggtc aattggactt cagaattcct ccccatttat aataaggtga ttccttgggg
     9181 atggaatccg tctttggtgc gtcgtttgca ggaagctgga tttcctgata cagcatatcc
     9241 ttcagtagag cgtatgaagc gtatccgtca aatatccgga cgtcagacgg ctgtaaaagt
     9301 gttacgacgc ctttgtaggc atataggtgg gaatattccc acattggggg aggcttttgt
     9361 attgtcatca acagaggaag tgaaggcttt tgtgttgtct catcctcgtg ctttgttaaa
     9421 agcgccatgg tctggtagtg ggagagggat acaatatgtt tcaggtagtt ttaccatccc
     9481 tctggaaggg tgggttcgac acatacttac cactcagcat gaggtgatag gagagccttt
     9541 ttatgataag cttttggatt ttgccatgga gttttttgca gacgagtggg aacaggtaca
     9601 ttttataggg tattctttat ttgaaacaga caagagaggt gtttataaag aaaacttgtt
     9661 ggctgcggat cgggttattg aagcgaggat atccacatat gtttctgcgg aaatcttaca
     9721 tcaggttggg aggatgttac aggtagagtt ggcggaagtt ataaaaggga gttacgaagg
     9781 ctatctgggg gtggatatga tgatatgccg tacccaaaac ggcgggtatg ccattcatcc
     9841 gtgtgtggaa ataaatcttc gtatgaatat gggagtggta gcacgtttga tatatgataa
     9901 ctatgtgtgt gatggcgtgc agggacggta tgttatagaa tattatgcaa agcccggtga
     9961 ggcatggcat tctcatcttg cgcttcaaga aaagcatcct ttatatttgg aaaatggaaa
    10021 agtgaagtcg ggttatttgt cacttacacc ggtagagaac aatacgtctt atcaggcata
    10081 tatcttaatt tgattttccg gataaaggaa aatcaaatta agaggggatg gttaccatcc
    10141 accccctaat gctttataca attttactaa tgtaatttgt ttgtctctta ttgcattact
    10201 taatcctatt tgtgcatcga aatagctacg ttgtgcatcc aatacatcca aatagcctat
    10261 tactccattg atgtattgca attgggccag ttccattgtt gctttagagg aacgttccag
    10321 ttgcagacgc gattcgtaga tatcttttat cttattgaag tccacaatgg cattgcgggc
    10381 ctctttgaat gcagtcagca ctgatttttc atagctgtag cattcctgtt cgtatgcggc
    10441 tttcttagcc tttagggttg ctctgtattt tcccatggcg aagagaggag tgagaagatt
    10501 gccactgata taatgaatgg gtgatttaaa gaaatcagag aattcttcac tttctacgcc
    10561 atattgtgct gtgaggctga gtcgtgggaa tatattggta taggcaatac ctacactggc
    10621 attggctgct attaatttct gttctgcttc gcgtacatcg ggacgacgtt ccaacagagt
    10681 ggagggtaga cctactggta atgtttcagg tagttttacc tcttcgggta gaatggaacg
    10741 ctgtatgcgg tgcgggtatt cgcctgccag gaatgcgata tcattttctt tcaatgaaat
    10801 tttcctttcc agttcaggaa ctaaagttgc ggtacgtgca tactccactt gtgcctgttg
    10861 ataggaagtt tctgaagtta gtcctccttc aaaacgaagc tttgccaggc gtactccttc
    10921 tttacgggca tagagtgttt gacgaacgat gttcagctca ttgtctaatg cgaccaattc
    10981 aaaataggct tgtgccactt cggacacaat actcattttc aaagcacgtt gcgcctcgat
    11041 gcttcccaga aattgtgcta tgcttttgtc ttttgcccaa cgcaggttac cccataagtc
    11101 taattcccaa gtcacggtaa gtttaccacc ctgttcgggg tcatttttat agttgtcacc
    11161 accataatta cttccttctt tttgggcata agcgcttccg ttcagttggg ggaaaaggtt
    11221 ggcaaagtct atgcgcttca ttgcggcaag ttcttttaca cgtgccgcag ctattttcat
    11281 gtctttgttg ttatccaacg tcttttctat caggctttgc aaggttgtgt ccgtatagat
    11341 ttcccaccat tgcatatcgg ctatagataa tgtatcctgt tgtcgtaatg tatctaattg
    11401 ttggggaaga tgtaagtcgg gacgtgtgta gtgcttacct aattggcaag aagtcagcaa
    11461 agtcattcct gatacggcta tatataataa tgtatgtttc atcatttctt tcatcttttt
    11521 atatccttat ttttgtttca tcttcgcttt catcttgtat atcagtacaa agaagaaagg
    11581 tactaacaaa attcccacag ttacagcaaa gatcattccg aagaatacac ctgtaccaat
    11641 agcctgacgg ctggctgaac ctggcccgct ggcaatgacc ataggtaaca tacctaagat
    11701 gaatgccaat gaagtcatca aaataggtcg gaaacggagc tgtgaagcat gaagtgcagc
    11761 ttgtactaca tctactcctt tgtctacttg ttctttggca aactctacaa taagaattgc
    11821 atttttggcg gctagtccta ccagcatcac caatccgatc tggaaataga catcattctc
    11881 cagtccacag ccccatacac ctagataagc acctaatgcg gctacaggca aagagagtaa
    11941 tactgcaacc ggtaccatcc agctttcgta taaggcagca aggaacaaaa atacgaacat
    12001 gaacactaat gccagcacca tgccggtctg tccacctgcc tgtttttcct ggaaggatag
    12061 tccgctccat tctacaccga tattttccgg taggtgttcg cgggctattt gttcgataat
    12121 ttccatagcc tgtcctgaac tgtaaccgtc tgcggcctca ccgagaatca cagaactgtt
    12181 gaacatatta aaacgtttga tgctgcccgg accagtggta tacgaagtgg tacccagcga
    12241 ggtgagcggt atcatggcat tgtctgtacc ccgtacaaaa aacaggttga tattctcctt
    12301 atgttcccgg tagggtgctt ctgcttgaat atatacacgg tagatgcggt taaacatatt
    12361 gaaatcgttt acatataccg aacctgtata agctttcata gtcgagaata catcggctaa
    12421 aggtactcct gagaatttta ctttgtcacg gtctacatca aaataaagtt gggggatatc
    12481 cgcttgtaaa gccgaagata aacctgataa ttccttacgt tttgatgcat aatacatcaa
    12541 tgtatccgta gcttgtacca aattttcgaa agtggcatct ccacgtgctt ccaattgcat
    12601 ttcgaacccg cccgaactgc ccaatcccgg aataacggga ggggtggaaa gatatacctt
    12661 gcattcgggg tattgtgaca tgtctttttt tacctgtgcc ataatattgt caatagtttg
    12721 cgagtcacgt tcctcccaag gttttaagat gacagtcagt tcacttcgtg cctgactggt
    12781 tcctacacgc ggactgcttc ccgccacact ttgcacatat tccactgccg gatttttcat
    12841 caggtattcc acagcacgtt ctgttacgat acgtgtacgt tccaacgttg caccttcggg
    12901 tagctccaac tctattttaa aatacccttg gtcttcgatg gggaggaagc tggtgggaat
    12961 gatgcgatgg attaacagga tggcgatcaa taccatgccg aatgtgctca gtacccgacg
    13021 cgggtgtttc acaatgtgtt tgataagccc tacatattta tgattgccga tagccagcca
    13081 ctcattgata cggcggaata cgatattctt tttcttgttc ggatcttccg gtttcaggat
    13141 aagcgaacac atgactggac tcaatgtcaa agctactacc gtagacagca atacggatac
    13201 tacgatggtt accgtaaact ggcgataaag ttgtccggta attccaccta gaaaacttac
    13261 gggaacaaat actgctgcca gtaccaaaga agtggcgata atggctcctg caagtccttc
    13321 catagctttc ttggtagctt ggtagggaga tagtttctcc tcttccatga tacgctccac
    13381 attctctact accacgatag catcgtccac cacaataccg atggcaagta ccaaccccaa
    13441 cagggtcagg atattaagcg agaatccgaa aatcaacatg aatccgaaag ttccaatcag
    13501 tgagataggt acggcaacta gtgggataac tgttgcacgc cagctttgga gtgaaaggta
    13561 tactacgata ataaccagta tcagggcttc aaacagtgtt ttgtacactt catgaataga
    13621 ttccgaaata tatgtggtca tatcgaaagg tatctcgtaa ctcattcctt cggggaaatt
    13681 cttgctgatt tcctccatag cttctttcac gctttttgct acttccatag cgttggctcc
    13741 cggtaacata tagatggcca ataccgctgc attttctttg ttaatggcac tctcggtatt
    13801 gtatgattgt gcttcgagtg agatgcgggc cacatcacgt aaacggatga tggaaccatc
    13861 ggcattggca cggactacga tttcctcaaa ctggcttaca gtagatagac gtccctgagt
    13921 agtgatggga atggttacgt ctaatccttg tacgggttgt tgtcccagta caccggctgc
    13981 tgattcccga ttttggtctt tcagtgcatt ctgcagatcg gctacggtca gaccgaaatt
    14041 ggccagtttg tcgggctgta cccaaatttg catggcgtaa tatcggcttc cgatgtttga
    14101 aacacgtcct acgccaggga tacggcggat taggtccagt acattcagag tagcaaagtt
    14161 gctaaggtat atttcatcga atttcgggtc ggtagaggta aggcataggg ttagcaattg
    14221 actggcagcc tgtttctcta ccgaaatacc attttgtata acttctgctg gaagacgtga
    14281 ttctgctaac ttgatacggt tctgtatttc tactgccgcc agatcgggat ctgccgagat
    14341 atcaaaagtg acggtggctg aaaaacctcc cgaattggaa ctgtttgatt ccatgtaaag
    14401 cattcctgga gtaccgttca attcctgttc tataggagtg gctaccgctt gtgatactgt
    14461 cagggcactg gcacccggat aggatgcgct gattttcact accggcgggg taatctgcgg
    14521 atattggtca atgggtagca tcgtgagacc gatgataccg acaatgacta ttaatatgga
    14581 gatgacagct gaaaataccg gtctgtctat aaagaaacta actttcataa tgtctattgt
    14641 ttttttgaat gcgtaaattt tcctccatag gggaattcgt attcgggagt gaaattatcc
    14701 gatcgtatct ttttcctccg tttttttgtc ttctacagca ggacttactt ttactttcat
    14761 gcctggattc agcttgtggt atccttctat aacaatgtct tctccgggag ccaagcctct
    14821 ttccaccact acttgattct ggaattcagg tcctaattca atgaaacgtc tctctactgt
    14881 agaatctttg cgcattacat aaatataggc accgcctttt tctatgataa cggactttaa
    14941 cggaactacc gtagcttttt ctctgacatc caataatagt tttactttgg tgaactgtcc
    15001 aggaagtaat atccgttctg gattcggcat ttcggcacgt acggagaatg tacctgtgcg
    15061 tggatcaact tgcggttcgg caaagtctac cagtcctttg tatggataaa tagtattgtc
    15121 tgctagagta atggaaacat tgggttgcca agagcgggta gagtcttttt gacctaagtt
    15181 cacattacgc tctttgcttt tcagatagtc tagagctgtc atgctgaaat ccactaatac
    15241 agtatcactt tttactacgg tggcaagcag tgatttgcca cttggaccta ccaatgtccc
    15301 taaatccacg tggcgttcac tgatatgtcc tgctaacgga gaacgaacta tcgtataacc
    15361 tagttccagt tctgcttgat caaggtcggc actactcata gctaccgagg cttctgctgt
    15421 ttcatatgca gcagtagcat tgtccaagtc caactggctg gcagcatttt gttcatatag
    15481 cggacggata cgttctaaat cgcgttttgc tttttgtgcc tgtgcttcat cttttttcaa
    15541 ttgggcacgc gctttgtcag ctttggctcg atattgatct tgattgataa caaacagcac
    15601 ttgattctta gtgacatatg taccttctgc gaaaagcatt tgttctaaat atccctctac
    15661 tcgggcacgt acttcaacga attgctgtgc acgtacgcgt cctacatatt caccatatat
    15721 ttccacatcg tcttgcgttg ccggtgctat ggcaactact ggaagttccg gcatctttgc
    15781 cggtcgatgg gaaacaatca ggtaaatccc gataactagt ccaataccta ttactacaag
    15841 cgctgttctt ttctttttta gcgcaatttc tttgtgtgta aaaaatagtt tcatacttta
    15901 gttttgttat tgtttaagat gccgtcagta ggaatacaag cagcgtgcca aactactgta
    15961 aatagccttt ccttttcata atcagtgttt tattactgcc ttttgttgat agggaaagtg
    16021 tggaaaacag gcaacagctg tagaataatt ccacagtagg cgaattaaat ttagtagagg
    16081 attatcgatt tggatgcaaa aatagtaaaa tagtgggtaa ttttaaaata tttattcatt
    16141 attcattatg atgaggacga tgttgtagtg ttagcagata tgtatgtaat ttaaattttg
    16201 cttgagatcg tcatatctgc aaccttgttg ttttgaaata cgctcccttt cattttgaaa
    16261 agggtagtgt ttcccttttt tttatgactt catataatat ctgtttgttt atcaatagtt
    16321 tataatgttg tttttcattt tggcatagta ttcgctatat acttgtcgaa tataaaaggt
    16381 ataaaaagat gggagaattt tataatccag ataaattata taaaggtgga agccggaata
    16441 atagcttgat aaataaaaaa atgatattcc gtgtattggg ggtattactt tttattgaat
    16501 ctgctatgtt cctgctttgt gcggctgttt ccttatgtta cggtgagcaa gattatcaat
    16561 attttctata taccattctt ttgaatacat tggtcggtgg agttttgcta atttgtagta
    16621 gaggtgctga gaatcggctg acacgacgag atgggtactg cattgtaact tttacttggt
    16681 ttttgtttac gttgtttgga atgttgcctt tttattttag tggaggaatc ccttcggtga
    16741 cggatgcctt ttttgaaacc atgtcgggtt ttactactac aggagctact atattggatg
    16801 atatagaatc tctttcacat ggtctgttat tttggcgtag cttgacacaa tggataggtg
    16861 gcttgggtat tgtctttttt actattgctg tgcttcctat tttcggggga ggaactatac
    16921 aacttttttc agctgaggct atcggggtga cgcacgacaa aacacatccc cggattgatg
    16981 tgatggctaa gtggctgtgg atgatatatg ctattcttac aattgcagaa actgtgctgc
    17041 tgatgatagg aggaatgagt ttttttgatg cggtatgtca ttcattctca acaacggcta
    17101 caggtggtta ttctaccaaa caagctagtg tagcttattg gaactctccg tttatagaat
    17161 atgtaatagc gatatttatg atcctttcgg gtattaattt ctctctctat tttatgtgtc
    17221 tgaaagggaa aggcaagcgt ttatttcagg atgatgaatt ccgttggttt atgaaatcag
    17281 tgagtattct gacacttgtt attacgtttg ccttagtttt tcagaatcat tatgattggg
    17341 aaaaggcatt ccgcagggct ctgtttcaag tagctacggc gcatacgtca tgcggctttg
    17401 caacggatga ttataacttg tggccatctt ttacatggat gcttcttatt tttgctatgt
    17461 tgtcaggtgg atgtacgggg tctactagtg ggggaatcaa aaatatgcgc cttatgattc
    17521 tggcgcgtaa tatcaaaaat gaattcaaac ggatgctg
//
