LOCUS       c00004_gnlPro..        22907 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MJHEEFDI_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:28:57
            Original ID  :: gnl|Prokka|MJHEEFDI_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22907
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..240
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 62; E-value:
                     1.2e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_1"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.3e-19, bitscore:
                     62.0, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="PAPAPAAAGAGDVPSPLAGKVVSLDVAAGASVKAGDQILTLEAMK
                     MNTIIYAPASGTLTAFCVNPGDTVQEGQALAKIG"
     protocluster    1..22907
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2861:12907]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2862..12907
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..22907
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22907
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             394..1983
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OAD_beta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_2"
                     /sec_met_domain="OAD_beta (E-value: 6e-159, bitscore:
                     520.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWGIAILLLYLGVAKQYEPLLMVPIAFGALIANIPDNGMLITQLN
                     QQVISSNEQGEVTSTSLNNVGYLRVHVAPLQQTPAKVPANLTTPEARAQYLETMQQPMQ
                     VYPGSQLTVSKIKSVRESQEKAKADAARLGDDSLTVDPNLKDFQNVTEDNGNEPVFLLT
                     NGEGTTVVRQQGVNYFDTSGNRVPVDLKTQKLEPLVVSAAGKYVAVGQHTQELLVTSIH
                     GGLYDWIGLGIKAEIFPPIIFLGVGALTDFGPLLAAPRTLLLGAAAQVGVAATFFMALF
                     MGFNPNEAASIGIIGGADGPTSIFLTMKLAPHLLGAVAVAAYTYMSLVPLIQPPIMALL
                     TTKKERLIRMKSLRTVSKSEKLFFAVLVTIVTILLIPDASPLIGMLMLGNFLRECKVTE
                     RLVQASQNEIINIVTIFLGTSVGLTMQGDRFLQAETLLIILLGIVAFGVATAGGVIAAK
                     LMNLIWRKNPVNPLIGSAGVSAVPMAARVSHNVGQKYDPSNYLLMHAMGPNVAGVIGTA
                     VIAGYYIATLAK"
     CDS             2021..2800
                     /locus_tag="ctg4_3"
                     /transl_table=11
                     /translation="MNSAASFSTPPEEEGPCGDWTYHEWAEAFSTNDLARSLPPGHIAV
                     CRVQTGGRGRFNRKWIGEEGGLWASFTVPLSAPADTAAGVHWGHLPLVAGLALFNMLRG
                     MGLDSVRLRWPNDLLAGKSKLAGILVERPAENMAVIGIGINVFNDVASIAGEIKDPPAR
                     LADLVRNCPSLHAVMASLGSHLNQVLSVFSHGGIPALQEGLARAWAGERPVSILTDDET
                     VRGIFTGIDDQGNPVLSLPAGAVRTIPAHLINRLLEE"
     CDS             2862..4358
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: AcetylCoA_hyd_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: AcetylCoA_hydro"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_4"
                     /sec_met_domain="AcetylCoA_hyd_C (E-value: 3.8e-46,
                     bitscore: 148.9, seeds: 181, tool: rule-based-clusters)"
                     /sec_met_domain="AcetylCoA_hydro (E-value: 2.7e-43,
                     bitscore: 140.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYKVLTPEEAASLIKHGHHIGLSGFTPAGTAKAVTAALAKIAEA
                     EHEKGNPFQVSVFTGASTGDSCDGILSRAKAIRYRAPYTTNVDFRKAVNNGEIAYNDIH
                     LSQMAQEVRYGFMGNVDIAIIEACEVTADGKIYLTAAGGIAPTICRLADKIIVELNAAH
                     SKSAMGLHDVYEPLDPPYRREISIFKPSDRIGKPYIQVDPKKIVGVVETNWPDEARSFA
                     AADPLTDKIGQNVADFLAADMKRGIIPSTFLPLQSGVGNIANAVLGALGRDKTIPAFEM
                     YTEVIQNSVIGLIREGRVKFGSACSLTVTNDCLEGIYRDMDFFRDKLVLRPSEISNSPE
                     VIRRLGVISINTAIEADIYGNVNSTHIGGTKMMNGIGGSGDFTRNAYISIFTCPSVAKD
                     GKISAIVPMVSHHDHTEHDVNIIITEQGVADLRGKSPKERAQTIIENCVHPDYKNILWD
                     YLKLSDGKAQTPQSIRAALGMHAELARSGDMKNVDWAQYK"
     CDS             4477..5178
                     /locus_tag="ctg4_5"
                     /transl_table=11
                     /translation="MNWMIYPAARAFIKVCAVLFGAGATAAALIHLFIPFFLRSPRTAA
                     PFLLLGTGAELLSILSLSFLMFWGARVLLASRGSKITRNLSMLAFLPALYALLIPFAGM
                     PASSQYTEMDRVWEAFLLLASVISFFSFPYTAGYGAAGRRLFLAWGISAAGCGLQSALF
                     FLAVLLRQFLTTAVPSLAAPVAWLAVLLSCGLEIMLAALSVILARRLFKNVMSIASMPE
                     PMDPAMPGNRP"
     CDS             5296..5490
                     /locus_tag="ctg4_6"
                     /transl_table=11
                     /translation="MKGFYGLEQTTSGNFRRHGHRMESIAGKQTAPSPENQGICRVVPS
                     ISLADLRQPYFTNSSKYRP"
     CDS             complement(5457..6320)
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MKGIVLAGGSGTRLHPVTLSVSKQLLPVYDKPMVYYPISVLMLAG
                     IREILIISTPRDLPLYRDLLGDGSRFGVSFEYREQPRPEGLAQAFIIGEEFIGKDSVAL
                     VLGDNIFYGRGLTEKLRRAAKLTSGATIFGYQVHDPQRFGVVEFNEEGKAVSIEEKPLR
                     PKSDMAVTGLYFYDNRVVEIAKRIPKSSRGELEITSVNQEYLKQGLLRVEKLARGYTWL
                     DTGTHDTLLEASMFVRTLEHHQGFKMACLEEIAFNNGWISPETLRSQAGAMNNNGYGRY
                     LDELVK"
     CDS             complement(6330..7382)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_8"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.2e-98, bitscore:
                     322.7, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVIVTGGAGFIGSNLVRLLLERGHEVLNIDALTYAGNIHSLDGS
                     ADSPAYRFLHADVRDASLMRRTLREYAPDWVMHLAAESHVDRSIDDPGNFMTTNVMGTF
                     SMLQAALEYYRSLEGEKKERFRFHHISTDEVYGSLGKEGLFTESTPYRPHSPYSASKAS
                     SDHLVRAWHDTYGLPVLITNCSNNYGPYQFPEKLIPVVILKALGGDPIPVYGKGENVRD
                     WLYVGDHCEALLKVVSCGKPGETYNIGGNNEKTNLELVELLCSHLDELRPRTDGRSYRE
                     QITFVQDRPGHDLRYAIDASKIRRELGWAPRQDHSSGFRKTIQWYLDHEEWWRGILSGE
                     YRLERLGTNG"
     CDS             complement(7514..8458)
                     /locus_tag="ctg4_9"
                     /transl_table=11
                     /translation="MTSGGDAAGMNPAIKAAVDHARQLGMNPYVVYDGLEGLIDGKIKE
                     ATRELTSDMIYRGGTLLRSSRSKRFFDYEFRRQAYEHLKERNIDKLIIMGGDGSFRALN
                     DFFNDFEVPFAGIPATIDNDIAGTDYCLGVDTAQNVILDCIDSVRDTARSHHRAFVIET
                     MGRDCGYLAMTTALCSAADICIVPEIPYDLESIYKRLQPVINEEGSCIIAVVAEGTRVA
                     QYLTRWLTERAGMDTRLTVLGHVQRGGSPTARDRLMGTRFATRAVEALNNGDINQIMVY
                     HDGQYGYASLDSVAGQQYSVNQDIINLCRELSC"
     CDS             8587..9318
                     /locus_tag="ctg4_10"
                     /transl_table=11
                     /translation="MNDTAAAILKATAALRDGTERLRFGAPVHVTYNPLAYAWNPHEQY
                     VRTYGNGEKGHLFLGMNPGPFGMAQTGVPFGEVDAVVNWLHIRGEVGRPEHTHPKRPVE
                     GFGCPRSEVSGRRLWGLFAEAFGTAENFFRHNYVANYCPLIWMGATGANITPDKLPAEQ
                     RAAVDAVCMEHLLSLITILNPHTLVGVGAYATQKLRDAASRLPGKNFTIGTLLHPSPAS
                     PIANKLWPERPIQQLKELGIL"
     CDS             9656..11122
                     /locus_tag="ctg4_11"
                     /transl_table=11
                     /translation="MAISDYIVTIGLEVHCQIKTKSKMFCSCETGFGFEPNTRVCPTCL
                     GLPGALPVLNEFAIERTLLTGLMLGCSSPEISQWDRKNYFYPDMAKNYQTSQLDLPLCL
                     GGEVPLYPWSYPNDVIKAGVPPFRTVKLTRIHLEEDAAKITHHANYSLIDYNRAGSALM
                     EIVSEPDIDTPEEAYAYLKSLQQILNYGDISDADMEKGQMRCDVNISLRPHGQKELGAK
                     VEMKNINSMSAVRRALHYEIRRQAEELDMGIPQIQSTRRWDDERGESVVMRTKEDAHDY
                     RYFPCPDLVPVRTAPLVEKVRGQIPELPQERQKRFMEEYGLSEYDANVLVGDLELARFF
                     EEAAQGTASGKKIANWVINNISAVLNEKGMRPSECPVKPGAIRELIAIIDDGTVSNNQA
                     KDVFAKMWDEPALAAAQAAKLLGFEKADSSFLDGIVREVISANPDKVAEIQGGNEKLLN
                     WLTGQVMKAAKGKANPKIVTEALKKSLSME"
     CDS             complement(11177..12907)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_12"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.7e-34, bitscore:
                     109.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYRVADQVVEILEKAGIKRIYGIVGDSLNPVTDALRRRKTIEWIH
                     VRHEEAAAFAASAEAQLSGNLAVCCGSSGPGNLHLINGLFDAHRNHAPVLAIASHIPQS
                     QVGMEYFQATHPEQLFKECSAYAELVSDASQAPGILMSAIQHAWARRDVGVVVLPGDIA
                     DAPAEMKNLVHPPSYTRENVVPEHESVSLLARMLDDHRRITFFCGAGCAGAEDKVVRLA
                     HRLKAPIAYTWRGKDYFEHDNSLGIGMTGLLGWGDAYKAMHESDMIVLWGTDFPYFNFI
                     PTKPEIVQIDRRGEVLGRRCRLDLGICGDVSVTAEALLNMVQEKTDSEHLDASLKRHAR
                     DVRDMNAYMEGSDKESPIRPEQLTTALNKHAASDAVFTVDTGTPCIWSARFLCATPGRR
                     TLASFNHGSMANAMPMAIGAQMEFPGRQVIALCGDGGLSMLLGDLITIVQYRLPVKIVV
                     YNNDCLDFIQLEMQAAGLIPWQINLNNPSFAAVADAVGIKGFLLDKSSQVDQMVDMFLN
                     YPGPALLDAHVDRDAIALPPYISMGQAADFSLAMMKQTLAGEVKQVWNTLAGNRKLFKP
                     "
     CDS             13048..13470
                     /locus_tag="ctg4_13"
                     /transl_table=11
                     /translation="VNLRFSGGKLSETAAAHHQNGQAQDSQRSRGRFRNLKPGKTGNPF
                     RAKCFIRPFNFTPCKVGINPARNGIAVAVHVAVVGQRVKQRTINIDIHRLALVCARDGQ
                     SNVKKASIQNNGSFRNISTVLSKRPVRSIQVSISHA"
     CDS             14307..16817
                     /locus_tag="ctg4_14"
                     /transl_table=11
                     /translation="MATLLGCLPTSPAEVAFPGPAPGTASAEQSASGYTLSNNILTAKF
                     ILRNGSLSFGGMTSRLGPIAKAGGDLFIINLQDGRSIKSSDLKAGNVKFIALQPNPKAF
                     RLADRFPGKAVSATFQALNGTLRISWRAVLRDHSHYLRQELRLASTKPIQMKNIIAMQY
                     DLVEGKAGAPSVSGNARGALIVNDLAFAALETPMGINTVGSAGNMEGGETAIWSADKWS
                     TASWTGNFNVPQELKKQYGEQVSSAEGPVSIDGKGACTVTFQYKGGDKGNNKLNLAGVQ
                     LLSSRGAVLDSDFHNGSTGDSNADNTYTVQVPSKGNYILRYWAQTKSEPIASKGEITFS
                     LPVKTLEEKQEAQAGESRLAQGLWSRKTTMQPGEIWDVSSVLGIFAPGQKRRSFLAYME
                     RERVMPYRPFIHYNSWYELNINRNNDSDPAKRMTEEQCLAVLKDWQEQFFQKRGMSIDA
                     FVWDDGWDEFNSLWDFHKMFPQGFKRIDAAAGRQKAGIGTWLGPVGGYGASKGKRLAYW
                     NVKHPDNKIGNFQLSNKEYFDAFVGRCSQMVKDYNMKYFKFDGISTHFHAKGPGNEEDA
                     EGIIRVLNALRKKKGDLYINCTVGTWASPFWFRYADSVWRQENDFGTIGAGDNRDKWIT
                     YRDRLVHEVFVQGSPLMPINSMMTHGLMVTKFGPPACMPRDPENVKKELRCATACGTSL
                     QELYVDRDLMSANGGVLWDELAKGIKWIRRNADVLDDVHWVGGNPWNKETNEGAVYGWA
                     AWNKNKATLALRNSSDQEKSLTGTLRSILDIPANVKGSITFKDSYDDQRTLDGFSGNSV
                     NIDKELSFTLKPFEVLVYEGGKVK"
     CDS             complement(16925..17578)
                     /locus_tag="ctg4_15"
                     /transl_table=11
                     /translation="MWSDLSHGLSVLVDALAFLSRSWGFWVCAGSVTGLAAVYAWWRKR
                     LALWAFALAFLSLLAVVGLACRQEACQKTFLWIQEPELQALSGKYEVESSPRERWFFRP
                     PELKRFFQISSSTLLLNEDGTCEISSFPRPEAWGKWISRPEDRDDLSVLEEDLVSSCRG
                     TWSLVKKGGYYGVSIVYSPGSCLTLYLGGEEAECLVMPVNPDDPLEAVTFEKTF"
     CDS             17746..20517
                     /locus_tag="ctg4_16"
                     /transl_table=11
                     /translation="MKSAAHHQGLSEQQVLENRTKYGINILTPPEKDPLWKQFLEKFSD
                     PIIKILLVALFLSVGVAFYQFFTGTEPASVFLEPAGILAAILLATCVGFAFEVSANKKF
                     EILNQVNDDTMVQVIRGGNICELPRRDVVVGDIVILNTGEEVPADGILLEAVSLQVNES
                     TLTGEPLIGKTTNEAEFKKDATYPSNHVLKGTTVADGHGVMEVTSVGDRTEYGKVYEGS
                     QIDNKVQTPLNRQLSRLGDLITWASYAIAALIVIGRLTLYFSHLPGPVEWLSAGTFILN
                     TVMIAVTVIVVTVPEGLPMSVTLSLALSMKSMLANNNLVRKMHACETMGAATVICTDKT
                     GTLTRNQMNVYKADFYGLGNAAPAEDKLGNLIREGIAVNSTAFLDYSDPGHIKALGNPT
                     EGALLLWLHGLGVNYLDLRENARVLEQLTFSTERKYMATVAESPLLGKKVLYVKGAPEI
                     VLGLCSTVLTPEGLVPAADMRPSIEKQLLTYQNQAMRTLGFAYRILEDDAPVFEDGRII
                     RKDLVYLGIAAISDPVRDDVPQAVKDCMDAGIRIKIVTGDTPGTAREIGRQIGLWTEED
                     TPDRLMTGVEFEQTPDAELLDRVMDLKIMCRARPMDKERLVKLLQKKDQVVAVTGDGTN
                     DAPALNAAQVGLSMGDGTTVAKEASAITILDNSFMSISRAVMWGRSLYRNIQRFIVFQM
                     TINVAACLIVLIGAFLGTESPLTVTQMLWVNLIMDTFAALALASLPPDERVMQEPPRKT
                     TDHIITRPMGRNILGVGILFVAFLFGLLQYFKHADVTSLTQFSLSGYFGSYLDFSSPEH
                     ELTGYELSLFFTIFVLLQFWNMFNAKAFNTHQSAFARMGASIGGFGVVALLILAGQYLI
                     VTFGGKMFNVVPLSWTDWGIIFAGTSLVLWFGELARAFTPGKSGSRPRTVRE"
     CDS             20600..21757
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_17"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 1.1e-08,
                     bitscore: 27.1, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLTRLTGSISGSAVFLFSLSLFFAGCKKTEEVPHETPTLIYEHP
                     VTMDIPVTGSWVGHLDGVDNASIVPQITGYLQTQNYANGAIVKKGEVLFRIDDSTFRDQ
                     ESKAKATLAQAQAQLQQLNYDAEIYKPLAAENAISKQKYEDTRLSALAAEAQVQQAEAA
                     LSLAEKNLSYTVLYAPFDGIAGISKTNIGDLVSPESGPLAVVSSVNPIRVNFAVTQQEW
                     IQQAGKNGNEGVQTGSKLDITLKDGTKYPEQATVTAIDRAFNPQTGTIRVQADLPNADY
                     LLRPGMFIIATARLATVKNALTVPAKSLLSTQGRFFVIVLDESSHPSIIPVQAGTQLGD
                     RQQVIPLKPDSLTPQSKVVVDGLLQAEAASRNPAARLKAVPSSNQ"
ORIGIN
        1 cctgcgcccg ctccggccgc cgccggcgcc ggagacgtgc ccagcccgct tgccggcaag
       61 gttgtttccc tggacgtggc tgctggcgcc tccgtgaagg ccggcgacca gattctgacg
      121 ctggaagcca tgaagatgaa caccatcatc tacgctcccg cctccggcac gctcaccgct
      181 ttctgcgtaa acccgggtga tacggttcag gaaggacagg ctctggccaa gatcggttaa
      241 tcccggcggc aaccgcccgg aacctccaac agttcctggc tccgactcag ataacaaacc
      301 gctacaataa cattccgtat gagtcttttt gattcattaa tcaccttttt acaggggatg
      361 ggcatcttct ccctatcatg gcaaatggta gggatgtggg gcattgccat cctgctcctg
      421 tatctgggtg tagccaagca atacgaacct ctcctgatgg ttcccattgc tttcggcgcc
      481 ctcatcgcca acattccgga caacggaatg ctcatcaccc agctgaacca gcaggtcatc
      541 tcctccaatg aacaggggga agtaacctcc acgtccctga acaacgtggg ctacctgcgc
      601 gttcatgtgg ctcctctgca gcagacgccc gccaaggtgc cggccaatct gaccacgccg
      661 gaagcccgcg cccagtatct ggaaaccatg cagcagccca tgcaggttta tcccggcagc
      721 cagctgaccg tttccaaaat caagtccgtg cgggaatccc aggaaaaagc caaagctgac
      781 gccgcccgcc tgggagacga cagtctgacg gtggatccca acctgaagga cttccagaac
      841 gtgacggagg acaacggcaa tgagccggtc ttcctgctca cgaacggaga aggaaccacc
      901 gtcgtccgcc agcagggcgt caattacttt gacaccagcg gcaaccgtgt tcccgtggac
      961 ctgaaaacgc agaagctgga acccctggtg gtttccgccg caggcaaata cgtggccgta
     1021 ggccaacata cccaggaact gctggtcacc tccatccacg ggggcctgta tgactggatc
     1081 gggctgggca tcaaggctga aattttcccg cccatcatct tcctgggcgt aggagccctg
     1141 acggacttcg gcccgctgct cgccgcaccg cgcaccctgc ttctgggcgc ggcggcccag
     1201 gtgggcgtag ccgccacgtt cttcatggcc ctgttcatgg gcttcaaccc gaatgaagcc
     1261 gcctccatcg gcatcatcgg cggagctgac ggccccacct ccatcttcct gacgatgaag
     1321 ctggctccgc acctgctggg cgccgtggcc gtggccgcat acacgtacat gtccctggtt
     1381 ccgctgatac agccgcccat catggcgttg ctgacgacca agaaggagcg cctcatccgc
     1441 atgaaatccc tgcggacggt cagcaagagc gaaaaactgt tcttcgccgt gctggtaacc
     1501 attgtcacca ttctgctgat tccggacgca tccccgctca tcggcatgct gatgctcggc
     1561 aacttcctgc gcgaatgcaa ggtgacggaa cgcctggttc aggcctccca gaatgaaatc
     1621 atcaacatcg tcaccatctt cctgggaacc tccgtgggtc tcacgatgca gggagaccgc
     1681 ttcctgcagg cggaaacgct gctgatcatt ctgctgggca ttgtcgcctt cggcgtagca
     1741 actgcgggcg gcgtcatcgc cgccaagctc atgaacctca tctggcgcaa gaatccggtc
     1801 aaccccctca tcgggtccgc aggcgtctcc gccgtcccga tggcagcccg cgtctcccac
     1861 aatgtgggcc agaagtacga cccctccaac tatctgctca tgcacgccat gggtccgaac
     1921 gttgcaggcg tgatcggcac cgcagtcatc gcgggctact acatcgccac tctggcgaaa
     1981 taaccagaat tgaaaattac tcccggcctc ggcccgtccc atgaattccg cagcctcatt
     2041 ttccacccct ccggaggagg aaggaccatg cggcgactgg acctatcatg aatgggccga
     2101 ggctttttcc accaatgacc tggcccgctc cctgcccccg gggcatattg ccgtctgccg
     2161 cgttcagaca ggaggccgcg gcaggttcaa ccgcaaatgg ataggggagg aaggcggcct
     2221 gtgggcatcc ttcaccgttc ccctgtccgc tcctgcggat acagcggccg gcgtgcactg
     2281 gggccatttg cccctggttg cggggctggc cctgttcaac atgctccgcg gcatggggct
     2341 ggattccgtg cgcctgcgct ggccgaacga cctgctggcg ggcaaatcca aactggcggg
     2401 aatactggtg gaacgcccgg cggaaaacat ggccgtcatc ggcatcggca tcaatgtttt
     2461 caatgatgta gcctccatcg ccggggaaat caaggaccct ccggcaaggc tggcggatct
     2521 tgttcggaac tgcccttcgc ttcatgccgt catggcttcc ctgggcagtc atttgaacca
     2581 ggttctttcc gtcttttccc acggcggcat ccccgctctc caggagggtc tggcccgggc
     2641 atgggccgga gaaaggccgg tttccattct tacggatgat gaaaccgtcc ggggcatttt
     2701 tacagggatt gacgatcagg gcaatcctgt gctatccctt ccggccggcg ccgtccgcac
     2761 cattccggcg cacctgatta acaggctcct cgaagaatga gcctgccgct ccgtttttac
     2821 acggggtttc tttctttttt catccaacaa aaatcactga catgagttac aaggtactga
     2881 caccagaaga agcagcaagc ctgatcaagc atggccacca tattgggctg agcggattca
     2941 cgcccgccgg aacggccaag gccgttacgg ccgcgctggc aaaaatcgca gaagcggaac
     3001 atgagaaggg gaaccctttc caggtgagcg tcttcaccgg tgcttccacc ggcgattcct
     3061 gcgacgggat cctttcccgg gccaaggcaa tccgctaccg cgctccctac accaccaacg
     3121 ttgatttccg caaggcggtg aacaacgggg aaatcgccta taatgacatc catttgtccc
     3181 agatggccca ggaagtgcgc tacgggttca tgggcaacgt ggacatcgcc attattgaag
     3241 cctgtgaagt cacggctgac ggcaaaattt acctgacggc cgcgggcggg atcgctccca
     3301 ccatctgccg cctggcagac aaaattatcg tggaattaaa cgccgcccac agcaagagcg
     3361 ccatgggcct gcacgacgtt tacgaacccc tggatcctcc ctaccgccgc gaaatctcca
     3421 tcttcaaacc cagcgaccgc atcggcaagc cgtacatcca ggttgacccg aaaaagattg
     3481 tgggcgttgt ggaaaccaac tggccggatg aagcccgttc cttcgccgca gcggatcccc
     3541 tgactgataa aatcgggcag aacgtggccg atttcctggc tgccgacatg aaacggggca
     3601 tcattccctc cacattcctg cctctccagt ccggcgtagg caacatcgca aacgcggtgc
     3661 tgggcgccct gggccgcgac aagacgattc ccgcgttcga gatgtacacg gaagtcatcc
     3721 agaactccgt catcggcctg attcgggaag gccgcgtgaa attcggcagc gcctgctccc
     3781 tgaccgtgac gaacgactgc ctggaaggca tttacaggga tatggacttt ttccgcgaca
     3841 aactggtgct ccgtccctcg gaaatatcca acagcccgga agttatccgc cgtctcggcg
     3901 tcatctccat caacaccgcc attgaagccg acatttacgg gaacgtcaac tccacgcaca
     3961 ttggcggcac gaagatgatg aacggcatcg gcgggtccgg cgacttcacg cgcaacgcct
     4021 acatctccat tttcacctgc ccgtccgttg ccaaggacgg caagatcagc gccatcgtcc
     4081 ccatggtttc ccaccatgac catacggaac atgacgtcaa tatcattatt accgagcagg
     4141 gggtcgcgga cctgcgcggc aagagcccga aagaacgggc ccagaccatt attgaaaact
     4201 gcgtccaccc ggattacaaa aacatcctct gggattacct gaagctgtcc gacggcaaag
     4261 cccagacgcc gcaatccatc agggccgctt tgggcatgca cgccgaactg gccagaagcg
     4321 gagacatgaa gaatgtcgac tgggcccagt ataagtaatt ccgcatgccg tcactcgcat
     4381 tggcatccat gaattcacgt taacccctca ggaccgcttc cgcaaaggga gcggtccttt
     4441 tccttttttc tatcccctct actccttttc ttcaccatga actggatgat ttacccggca
     4501 gccagggctt tcatcaaagt ctgcgccgtt cttttcggcg cgggcgcaac agcagcagcc
     4561 ctcatccatc tgttcatacc ttttttcctc cgctctcccc ggacagccgc gcccttcctg
     4621 cttttgggaa caggggcgga attgctctcc atcctttccc tgtccttcct catgttctgg
     4681 ggcgccagag ttctgctggc ctcccgggga agcaagataa caagaaatct gagcatgctg
     4741 gccttcctgc ccgccctgta cgccctcctc attccgtttg cgggcatgcc cgcctcatcg
     4801 caatatacgg aaatggacag ggtttgggag gccttcctcc ttctggcgtc cgtcatttct
     4861 ttcttttcct tcccttatac ggcgggatac ggcgccgcag gcaggagatt attcctggcc
     4921 tggggcatct cggcggcagg atgcggtttg cagagcgccc tgttttttct tgccgtcctg
     4981 ttgcgtcaat tcctgaccac agcagttccc tccctggcag cgccagttgc atggctggcc
     5041 gttcttttgt cctgcggcct ggaaatcatg ctggcggccc tttccgtcat tctggcgcgg
     5101 cgcctgttca aaaatgtcat gtccatagcg tccatgccgg aaccgatgga tcccgccatg
     5161 ccgggcaacc gtccctgact ttcccccctg ccttcatgtt tacagccagt tggaaggggt
     5221 tatcccccag tccgcggcat gaatacgtga accactcacg gcagccttct tccaacccgg
     5281 ctgccgcctc ccggcatgaa aggcttttac ggccttgagc agacaacgtc cggaaatttc
     5341 cgccggcacg gccaccgcat ggaaagcatc gccgggaagc aaaccgcccc ctcccccgaa
     5401 aaccaaggga tttgcagggt cgtcccttcc atttcccttg ctgacctcag acagccctat
     5461 ttcaccaatt catccaaata ccgcccataa ccgttattgt tcatggctcc ggcctgggaa
     5521 cgcagcgtct ccggggaaat ccagccgtta ttaaaggcta tctcctccag gcacgccatc
     5581 ttgaacccct ggtgatgctc caacgtgcga acgaacatgg aagcctccag aagggtatcg
     5641 tgcgtgcccg tatccagcca cgtatagccg cgcgccagct tttccacgcg caacaggccc
     5701 tgcttcaggt attcctgatt cacggaggta atttccaact cgccccggga ggacttggga
     5761 atccttttgg ctatctccac cacccggttg tcgtaaaaat agaggcccgt caccgccatg
     5821 tccgatttgg gcctgagcgg tttttcctca atagataccg ccttcccttc ctcattgaat
     5881 tccactaccc cgaaacgctg cgggtcatgc acctggtacc cgaaaatggt cgctccgctc
     5941 gtcagtttgg cggcccgcct cagcttctcc gtcaggccgc gtccgtaaaa aatattgtcc
     6001 cccagcacca gggctacgga atcctttccg atgaactcct ctccaataat aaaggcctgc
     6061 gccagcccct ccggcctggg ttgttccctg tattcaaagg agacgccgaa cctgctgccg
     6121 tcccccagca aatcccggta caggggcagg tcccggggcg tggaaatgat gaggatttcc
     6181 cgtattccgg ccagcatcag cacggagatg ggataataaa ccatcggctt atcgtaaacg
     6241 ggcagcaatt gcttgctgac ggaaagcgta acgggatgca gccgcgtgcc gcttcccccg
     6301 gccagaacaa tacctttcat atcaacctcc tagccattgg ttccaagacg ttccaggcgg
     6361 tattccccgg acaggatgcc ccgccaccat tcctcatggt ccagatacca ctgaatggtc
     6421 tttctgaatc cggaagaatg gtcctggcgc ggagcccatc ccaattccct ccgtattttg
     6481 gaagcgtcaa tcgcatagcg caggtcatgg cccggcctgt cctgaacaaa ggtgatttgc
     6541 tcccggtagc tccggccgtc cgttcgcggc cgcaattcat ccagatggga acacagcagc
     6601 tccaccagtt ccagattggt cttctcgtta ttgccgccga tgttgtacgt ctctccgggt
     6661 tttccgcagg aaacgacctt cagcagcgcc tcgcagtgat cccccacata cagccaatcc
     6721 ctcacgtttt cccctttgcc gtatacaggg atggggtccc cgcccagcgc tttcaggata
     6781 acgacgggga tcagcttttc cgggaactgg taagggccgt aattgttgga acagttggtg
     6841 atcagcacgg gcagcccgta cgtatcgtgc caggcgcgca ccaggtggtc gctggaagcc
     6901 ttgctggcgg aatacgggga atgggggcga tacggcgtgg actccgtgaa caggccttcc
     6961 tttcccaggg agccgtacac ttcatccgtg gaaatgtggt ggaagcggaa acgctccttt
     7021 ttctctccct ccagggaacg gtaatattcc agagcggcct gaagcatgga aaaagtgccc
     7081 atgacgttgg tggtcataaa atttcccgga tcgtcaatgg aacggtccac atgggattcc
     7141 gccgccaggt gcatcaccca gtccggagcg tactcccgca aagtgcgccg catcagggaa
     7201 gcgtcccgga cgtcggcgtg cagaaagcgg tatgccggag aatccgccga gccgtccagg
     7261 gaatggatgt tgccggcata ggtcagggcg tcaatattca ggacttcatg gccgcgctcc
     7321 agcagcagcc tgaccagatt ggagccgatg aatccggcgc cgcccgtaac gataactttc
     7381 atagcactgt tttcagggaa agatgcggcg tcatcataca gcaacggtgt tttttttcaa
     7441 aacaaatccg cccatgccgc gggaacgtgg cggcatgggc gggaaaaagc gggttccgta
     7501 accgctgaga cggctagcag ctcagctccc ggcaaaggtt gatgatatcc tggttcacgg
     7561 agtactgctg cccggcaacg gaatccaggg aggcatagcc gtactggccg tcatgataca
     7621 ccatgatctg gttgatgtcc ccgttgttca gagcttccac ggcgcgggtg gcaaaacggg
     7681 tgcccatcag gcggtcacgg gcagtggggg aaccgccgcg ctgcacatgg cccagcacgg
     7741 tcaggcgggt atccatgccg gcgcgttccg tcagccagcg ggtcaggtac tgcgccacgc
     7801 gggtgccttc cgccaccacg gcaatgatgc agcttccctc ctcattgatg acaggctgga
     7861 ggcgcttgta aatggattcc aggtcatacg gaatttcagg gacaatgcag atgtccgccg
     7921 cgctgcaaag agcggtggtc atcgccagat agccgcagtc ccggcccatc gtttcaatca
     7981 cgaaagcgcg gtgatgggaa cgggccgtat cacggacgga atcaatgcag tccagaatca
     8041 cgttctgggc cgtgtccacg cccaggcagt agtccgtacc ggcaatgtcg ttgtcaatcg
     8101 tggccggaat accggcaaaa ggcacttcaa aatcattgaa aaagtcgttc agggcgcgga
     8161 aagagccgtc tccgcccata atgatgagct tgtcgatgtt gcgttccttc agatgctcgt
     8221 aggcctgcct gcggaattcg tagtcgaaaa agcgcttgga ccgtgaggaa cggaggagag
     8281 ttccgcccct gtagatcatg tcgctggtca gctcccgggt agcttccttg atttttccat
     8341 caatcagtcc ttccaaaccg tcataaacaa cgtacggatt cattccaagc tggcgggcat
     8401 ggtccactgc cgccttgatc gccgggttca ttccggcggc gtcgccgcca gatgtcataa
     8461 tggctattcc actcataagt aataaggtta acttgtccgg ggggaaatgt taccgggcgg
     8521 aacaaataat gcaagcgcgg agtttttact ggcgcaataa acggcaacgc ttcatgatgc
     8581 ggaggcatga acgacactgc agcagccatt ctgaaagcca cggccgccct ccgggacggc
     8641 acggaacggc tccggttcgg agctccggtc catgttacct acaatcctct tgcttatgca
     8701 tggaacccgc atgaacagta tgtgcgcacc tatggaaacg gggaaaaggg ccatttgttc
     8761 ctgggcatga atcccggccc cttcggcatg gcccagacgg gcgtcccctt cggggaagtg
     8821 gatgccgtcg tcaactggct gcacatccgc ggagaggtgg ggcggccgga acatacccat
     8881 cccaaacgtc ccgtggaagg cttcggctgc cccaggtcgg aagtcagcgg ccgccgcctt
     8941 tggggacttt tcgcggaagc tttcggcacc gcggaaaact tcttccggca caattacgtg
     9001 gccaattact gcccgctgat ttggatgggc gccaccgggg ccaacatcac gccggacaaa
     9061 ctgccggcgg aacagcgcgc cgccgtggac gcggtatgca tggagcacct gctttccctc
     9121 atcaccatcc tgaatcccca cacgctggta ggggtgggag cctacgccac gcagaaactg
     9181 cgggacgccg cctcccggct ccccggcaag aacttcacca tcggcacgtt gctccaccca
     9241 agccccgcca gccccatcgc caacaaactc tggccggaac gccccatcca gcagcttaag
     9301 gaactgggca ttttataaag aatggggagg ttagagcgga gagttccgtg acatgaaagg
     9361 aatcaccgaa gcaacaagcc ggaaatttgc ggttcatgtt gttcacctgc ggcaattccc
     9421 gcgccacggc gggagcgggc ccgtgttttc aaacaatgat tgagacgcgg cgccggcgtc
     9481 accggggcgg agaaggacat aaacgcctcc ccgcctccat tgcaaaaaca gccttccgcc
     9541 agaccaatca tcatctttag ccggaaaacc ctccgctctc ccccgcaggc ctttttactg
     9601 gacagggaga aaagggttcc gtacagtttc cgcgatcttc aagcgttccg aatttatggc
     9661 aatttcagat tacatcgtga ccattggcct ggaagtccac tgccagatca agacaaagag
     9721 caaaatgttc tgctcctgcg aaaccggctt tggctttgaa cccaatacgc gtgtgtgccc
     9781 cacctgcctg gggctgccgg gcgccctgcc cgtcctgaat gaattcgcca ttgaacgcac
     9841 gctgctgacc ggcctgatgc tgggatgttc cagcccggag atttcccagt gggaccgcaa
     9901 gaattatttc tatccggaca tggctaaaaa ttaccagacc tcccagctgg atcttccgct
     9961 gtgcctggga ggggaagtgc ccctgtaccc ctggtcctat ccgaatgacg tgatcaaagc
    10021 tggcgtcccc cctttccgca ccgtgaagct gacccgcatc cacttggaag aagacgctgc
    10081 gaagattacc catcacgcca attattccct gattgactat aaccgcgcgg gatccgccct
    10141 gatggaaatc gtttccgagc cggacatcga caccccggaa gaagcctatg cctatctcaa
    10201 gtccctccag cagattctga attacgggga tatctccgat gcggacatgg aaaagggcca
    10261 gatgcggtgc gatgtgaata tttccctgcg tcctcacggg cagaaagaat tgggcgccaa
    10321 ggtggaaatg aagaacatca actccatgtc cgccgtccgc agagcccttc attatgaaat
    10381 ccggcgccag gcggaagaac tggacatggg cattcctcaa atccagtcca cccgccgctg
    10441 ggacgacgaa cgcggagaaa gcgtcgtcat gcgtaccaag gaagacgcgc acgattaccg
    10501 ttatttcccc tgcccggatc tggttcccgt acgcacggct cccctggtgg agaaggtgcg
    10561 cggacagatt cccgagctgc ctcaggaacg gcagaaacgc ttcatggagg aatatggcct
    10621 gagcgagtat gacgccaacg tgctggtggg ggacctggag ctggcacgct tttttgaaga
    10681 ggcggcgcag ggaaccgcca gcgggaaaaa aatcgccaac tgggttatca acaatatttc
    10741 cgccgtgctg aatgaaaaag gcatgcggcc gtctgaatgc cccgtgaaac ccggagccat
    10801 ccgggagctg atcgccatta ttgacgacgg caccgtttcc aacaaccagg ccaaggacgt
    10861 attcgccaaa atgtgggatg agccggccct cgccgcagcg caggccgcca agctgctggg
    10921 ctttgaaaag gcggattcat cttttctgga cggcatcgtg cgggaagtta tttccgccaa
    10981 tccggacaaa gtagcggaaa tacagggcgg caacgaaaag ctcctgaact ggctcaccgg
    11041 ccaggtcatg aaggccgcca aaggcaaagc caacccgaaa atcgtgacgg aagcgctgaa
    11101 aaaatccctt tccatggagt gaccccaaac aaagagccac gtcttttacc ggttcccggc
    11161 ccttgcccgc aggacatcac ggtttgaaca gtttcctgtt tccggccagg gtattccata
    11221 cctgcttcac ttccccggcc agcgtctgct tcatcatggc aagggaaaag tccgcggcct
    11281 ggcccatgct aatgtaagga ggcagagcaa tggcgtccct gtccacatgc gcgtccagca
    11341 gagcggggcc gggataattc aggaacatgt ctaccatctg gtccacctgg ctggacttat
    11401 ccaataaaaa gcctttgatg ccgacggcat ccgctacggc ggcaaaagag gggttgttca
    11461 ggttgatctg ccatggaatc agcccggccg cctgcatttc caactgaatg aaatccaggc
    11521 agtcattatt atataccacg attttcaccg gcagcctgta ctggacaatc gtgatgagat
    11581 cccccagcag catggacagg ccgccatctc cgcacagggc aattacctgc cgtccgggga
    11641 attccatctg cgccccaatg gccatcggca tggcattggc catggagcca tgattgaaag
    11701 acgccagcgt cctccttccc ggcgtagcgc acaggaacct tgcgctccag atgcaggggg
    11761 ttccggtatc taccgtaaat acggcgtcgg atgccgcatg cttgttcaag gcggtcgtga
    11821 gctgttccgg acggatggga gactccttat cgcttccttc catataggcg ttcatatccc
    11881 tcacgtccct ggcgtggcgt ttcagggagg cgtccaaatg ctcggaatcc gttttttcct
    11941 gcaccatgtt cagcaacgcc tccgccgtga cggaaacatc cccgcaaata cccagatcca
    12001 ggcggcagcg gcggcccagc acttccccgc gcctgtcaat ctgcacgatt tcaggcttgg
    12061 tgggaatgaa attgaaatag gggaaatccg tcccccacaa tacgatcata tcgctttcat
    12121 gcatggcctt gtaggcatct ccccatccca gcagccccgt catgccgatg cccagggaat
    12181 tgtcatgttc aaaataatcc ttgcccctcc atgtgtaggc aatcggagct ttcaggcggt
    12241 gcgcgagccg gacgaccttg tcttccgctc ccgcgcagcc ggcgccgcag aagaaagtaa
    12301 tgcggcggtg gtcgtcaagc atccgtgcca gaagggatac ggattcatgc tcaggaacaa
    12361 cattctcccg cgtgtaggaa ggaggatgca ccagattctt catctccgca ggggcgtccg
    12421 caatgtctcc gggcaagacg acgacgccta cgtcgcgcct ggcccacgcg tgctgaatgg
    12481 cggacatcaa aatgcccgga gcctgggaag catccgaaac cagttccgca tatgcactgc
    12541 attccttgaa aagctgttcc ggatgagtgg cctggaaata ttccatacct acctggctct
    12601 gcgggatgtg ggaggcgatg gccagcaccg gagcatgatt ccggtgggcg tcaaacaatc
    12661 cgttgatcaa atggaggttt ccggggccgc tgctgccgca gcatacagcc aggttcccgc
    12721 tcagctgggc ttccgcgctc gcggcaaagg ccgccgcttc ctcatgccgc acatgaatcc
    12781 attcaatggt cttcctcctt ctcaaagcat ccgtaacggg gttcaggcta tcccccacaa
    12841 taccgtaaat tctcttaatt cccgcctttt ccaaaatttc aacgacctga tcggctaccc
    12901 tgtacatgca gattagacac cgtccaatct ccaacggatt cattcttatg tgtcatcctc
    12961 ccgccttttc cgcaccggaa aaaatatctg cggttatctt cccaatacaa gaaataataa
    13021 ggccgccgcc ttttcaggca gcggcccgtg aatttacggt tttccggagg aaaactgtca
    13081 gagacggcgg cggcgcatca tcaaaacggc caggcccagg attcccagag aagccgaggc
    13141 cggttccgga acctgaagcc cggcaaaacc ggcaatccgt tccgcgccaa gtgtttcatc
    13201 cgtccattta acttcacccc atgtaaggtc gggattaatc cagctcgtaa tgggattgcg
    13261 gttgccgttc atgttgccgt tgtaggccag cgtgtcaaac agagaaccat taacatagac
    13321 atccacagac tggctctggt ctgcgcccgt gacggacaaa gtaacgttaa gaaggcctcc
    13381 attcaaaaca acggaagttt cagaaacatc tccacggttt tgagtaaaag acccgttaga
    13441 agtattcaag tttccatctc ccatgcctag cttggcgtct gaagtcagat acaaggcatt
    13501 tgccccgtaa ttctgagctg cgttggttcc ataataacca aacagcgctg tttgagttcc
    13561 ttccgttaag gaagaggtat ccagccagag ggagatcgtg taactggaag cataaaaatt
    13621 accgccataa gggatggagt tattaggaat agagctgttt gagaggctcc cgaacgtcat
    13681 atcttttccc aatgcaactc cttcagttgt cgtcgtcgta ccggaattgt aaagcgtttc
    13741 ggactccgga gcaacagagc cgggatccgc caacgccggt acggaacaac acaccgcaat
    13801 ggccattgat gctaatgttt ttttcatttt ctatgtatga tggattgagc tattagagag
    13861 atattccccg ccctctgtat atcggattcc aaatccgttc tttttctatt cagccaagaa
    13921 agatgagaat aagtttttcc aattctctaa ataaattttt aatattctta ttttctatta
    13981 cttacggata aaaataaaac gcagaataaa tgttttttgt agcggctcca aaattgctgt
    14041 ttaggaacag aaatcccttt tttcaaaata gaaaaaattg taataatatt ttcatatctg
    14101 aaatgttagg ttgaccccgg atttggaatc cggttgtttt cccgcagcca tcaaaaaagc
    14161 aacataagat tttcatattc aataaaaatc atttttcttt cactccattt ccaggacctt
    14221 tttcttgaaa aagatccttc cccaaattat cctgccgcta gctgtaatat tatttcatca
    14281 tgaaattttt caaaacaccc cttgtcatgg caaccctgct gggctgcctg cccacctctc
    14341 cggcagaagt tgcctttccg gggcctgccc ccggaacagc cagcgcggaa caatccgctt
    14401 ccggctatac tctttccaat aacatcctga cggccaaatt tatccttcgg aacggaagtc
    14461 tttcctttgg aggaatgact tccagactgg gccccatcgc caaggctggg ggagatttat
    14521 tcatcatcaa tcttcaggac ggacggagca ttaaatcctc cgatctgaaa gcgggaaacg
    14581 tcaagttcat cgcccttcag cccaacccca aggcattcag gctggctgac cgctttccag
    14641 gaaaagccgt cagcgcaacg tttcaggccc tgaacggcac ccttcgcatc tcctggcgcg
    14701 ccgtgctcag ggaccattcc cattacctcc ggcaggaact ccgcctggca agtaccaagc
    14761 ccatccagat gaaaaacatc atagcgatgc aatatgacct ggtagaaggg aaagccgggg
    14821 caccctccgt ctccggcaac gccagaggcg cactcatcgt caatgacctg gcgttcgccg
    14881 ccctggaaac tcccatgggc attaataccg tggggagcgc cggaaatatg gaagggggag
    14941 aaaccgccat ctggagcgcg gacaagtggt ccacagcttc atggacagga aatttcaatg
    15001 tcccccagga gctgaaaaag cagtacggag aacaggtttc cagtgcggaa ggtccggttt
    15061 ccattgacgg caaaggagca tgcaccgtca ccttccagta taagggaggg gacaagggca
    15121 acaataagct gaacctcgcc ggcgtgcagc ttctctcttc cagaggagcc gtccttgact
    15181 ctgatttcca caacggcagc accggggatt ccaatgccga caacacctac acggtacagg
    15241 ttccctccaa gggaaattac attctgcgct actgggccca gaccaagagc gaaccgattg
    15301 ccagcaaggg ggaaatcacc ttttccctgc ccgtgaagac gcttgaggaa aagcaggaag
    15361 cccaggcggg cgaatcccgg ctggcccagg gtctctggag ccgtaaaacc accatgcagc
    15421 ccggagaaat atgggacgta tcctccgttc tcggaatttt tgcccccggc cagaaacgcc
    15481 gctccttcct ggcctatatg gaacgggaac gcgtgatgcc ctaccgccca ttcatccatt
    15541 ataattcctg gtatgaactg aacatcaacc gcaataatga ttcggacccc gccaagcgca
    15601 tgacggaaga acaatgcctg gccgtcctga aagactggca ggaacagttt ttccagaagc
    15661 gcggcatgtc cattgacgcc ttcgtctggg atgacggatg ggatgaattc aacagcctgt
    15721 gggatttcca caagatgttc ccgcaaggct tcaagcgcat tgacgccgcc gccggccggc
    15781 aaaaggccgg catcggcacg tggctgggtc cggtgggggg ctacggagcc tccaagggca
    15841 agcgcctcgc ctactggaac gtaaagcacc cggacaacaa aatcggcaac ttccagctct
    15901 ccaacaagga atattttgac gcctttgtgg gccgctgctc ccagatggtg aaggactaca
    15961 atatgaagta cttcaaattc gacggcatca gcacccactt ccatgccaag gggcccggca
    16021 acgaggagga tgcggaaggc atcatccgcg tgctgaacgc cctgcgcaag aaaaaggggg
    16081 atctttacat caactgcact gtaggaacct gggcatcccc cttctggttc cgttatgcgg
    16141 attccgtatg gaggcaggag aatgacttcg gcaccatcgg agcgggcgac aaccgcgaca
    16201 aatggatcac ctaccgcgac cgcctggtgc atgaagtttt tgtgcagggc tccccgctga
    16261 tgcccatcaa ttccatgatg actcacggcc tgatggtcac taaattcggg cctccggcat
    16321 gcatgccccg cgacccggaa aacgtcaaga aagaactccg ctgcgccacg gcctgcggca
    16381 cttccctcca ggagctatac gtggatcggg acctgatgag cgccaacggg ggagttctgt
    16441 gggacgaact ggccaagggg atcaagtgga tacgccgcaa tgcggacgtt ttggacgacg
    16501 tgcactgggt gggcggcaat ccgtggaaca aggaaaccaa cgaaggggcc gtgtacggct
    16561 gggccgcatg gaataaaaac aaggccaccc tggccctccg caattcctcc gaccaggaga
    16621 agagcctgac cggtaccctg cgcagcatcc tggatatccc cgcaaacgtc aagggctcca
    16681 tcaccttcaa ggattcctat gacgaccagc ggacgctgga cggcttctcc ggaaattccg
    16741 taaacattga caaggagctc tccttcacgc tgaagccttt tgaagtgctg gtgtacgaag
    16801 gaggcaaagt caaatagaat caacagtctg tacgcccggc cagaaccgga acggcgttgg
    16861 aaaaaacatg tagagggagg cggtgccccc gcctcccttc tttttccgtc cggaagaacc
    16921 aggatcagaa tgttttttca aacgttaccg cttccagcgg atcgtcagga ttgaccggca
    16981 tcaccaggca ttccgcctct tccccgccca ggtacagcgt caggcagctc ccgggggaat
    17041 agacaatgga gacgccgtaa tatccccctt ttttcaccag ggaccaggtt ccgcggcagg
    17101 aggaaacgag gtcctcctcc agcacggaaa ggtcatccct gtcttccggg cgggaaatcc
    17161 actttcccca cgcctccgga cgcgggaagg aggaaatctc gcacgttccg tcttcattca
    17221 ggagaagcgt ggaggagctg atctggaaaa agcgcttcag ctccgggggg cggaaaaacc
    17281 accgctccct gggggaggat tccacctcgt actttccgga cagggcctgg agttccggtt
    17341 cctgaatcca caggaaagtc ttttgacacg cctcctggcg gcacgccagg cccaccacag
    17401 ccaacaggga aaggaaagca agggcaaacg cccacagagc cagccgcttt ctccaccacg
    17461 catacacggc ggccagtccc gtcacgctgc ccgcgcagac ccagaacccc caggaacggg
    17521 aaaggaaggc aagggcgtcc accaggacgg aaagtccatg agaaagatca ctccacatag
    17581 gcgctccaga atctccggaa tattgtcaaa gtcaagacaa caatgccgcc ttttaaggca
    17641 cggcgcgcag cctgcggccc gctaaaaaac tcccgtcatc acccctgaaa atcttcctcc
    17701 gcacttttct cacgggctcc aatcaggtaa agaagcatct caaccatgaa aagcgcagca
    17761 catcatcagg ggctttcgga acagcaggtt ctggaaaacc ggaccaaata cgggatcaat
    17821 atcctgacac ccccggagaa ggatcccctg tggaagcaat tcctggagaa attttcagac
    17881 cccattatca agattctgct ggtggccctg ttcctgtccg taggcgtagc tttctaccag
    17941 tttttcaccg gaacggaacc ggccagcgtc tttctggagc ccgcgggcat cctggcggcc
    18001 atcctgctgg ctacctgcgt ggggttcgcc ttcgaggtaa gcgccaacaa aaagtttgaa
    18061 atcctgaacc aggtcaatga cgacaccatg gtccaggtca tccgcggcgg caatatctgc
    18121 gaattgcccc gccgggacgt ggtggtgggc gatatcgtta tcctgaacac aggagaggag
    18181 gtcccggcgg acggcatcct gctggaagcc gtttccctcc aggtcaacga atccacgttg
    18241 acgggggaac ccctcatcgg caaaaccacg aatgaagcgg aattcaagaa agacgccact
    18301 tacccctcca accacgttct gaaaggaact accgtggcgg atggccacgg cgtcatggaa
    18361 gtgacgtccg taggggacag gacggaatac ggcaaggttt atgaaggctc ccagatcgac
    18421 aataaggtgc agacgcccct caaccgccag ctttccaggc tgggggacct catcacctgg
    18481 gccagctacg ctatcgccgc cctcatcgtc atcgggcggc ttacccttta cttctcccac
    18541 ctgcccggcc ccgtggaatg gctgagcgcg ggaaccttca ttctgaatac cgtcatgatc
    18601 gccgtgaccg tcatcgtagt cacggtgccg gaagggctgc ccatgagcgt caccctgagc
    18661 ctggccctga gcatgaagag catgctcgcc aacaataatc tggtgcgcaa gatgcacgcc
    18721 tgcgaaacca tgggggccgc caccgtcatc tgcacggaca agacgggaac cctgacgcgc
    18781 aaccagatga acgtatacaa ggctgatttc tacggcctgg ggaatgctgc cccggcggaa
    18841 gacaagctgg gcaatctgat ccgggagggt atcgccgtca actccaccgc ctttctggat
    18901 tactcggatc cggggcatat caaggccttg ggaaatccca cggaaggggc gctcctcctg
    18961 tggctgcacg ggctgggcgt gaattacctg gatttgcggg aaaacgcccg cgtgctggaa
    19021 cagcttactt tctccacgga acgcaagtac atggccaccg tggcggaatc ccccctgctg
    19081 ggtaaaaaag tcctttacgt gaaaggcgcg ccggaaatcg tgctgggcct ctgctccacc
    19141 gtcctgacac cggaaggcct ggttcccgcc gcggacatgc gtccctccat tgagaaacag
    19201 ctcctgacct atcaaaacca ggccatgcgt acgctgggct tcgcataccg cattctggag
    19261 gatgacgccc cggtattcga agacggccgc attatccgca aggatctggt ttacctgggc
    19321 atcgccgcca tttccgaccc cgtccgggac gatgtgcccc aagccgtgaa ggactgcatg
    19381 gacgcgggca ttcgtatcaa gatcgttacg ggggacaccc ccggcaccgc acgggaaatc
    19441 ggacgacaga tcggcctgtg gacggaggag gacacgccgg accgcctgat gacgggagta
    19501 gagtttgagc agactccgga tgcggaactg ctggaccgcg tgatggatct gaaaatcatg
    19561 tgccgtgcca ggcccatgga taaggaacgg ctggtaaagc tgctccagaa aaaggaccag
    19621 gtagtggccg ttaccgggga cggcaccaac gacgcccccg ccctgaacgc cgctcaggtg
    19681 ggcctctcca tgggggacgg cactaccgta gccaaggaag ccagcgccat caccatcctg
    19741 gacaattcct tcatgagcat ttcccgcgcc gtcatgtggg gacgctccct gtacaggaat
    19801 atccagcgct tcatcgtctt ccagatgacc atcaacgtgg cggcctgcct cattgtgctc
    19861 atcggcgcgt tcctgggcac ggaatccccc ctcaccgtca cgcagatgct ctgggtcaac
    19921 ctcatcatgg acaccttcgc cgcgctggcc ctggcctctc tgccgccgga cgaacgcgtg
    19981 atgcaggagc cgcctcgcaa gacgacggac cacatcatca cccgccccat gggcaggaac
    20041 attctgggcg tgggcatcct gttcgtggcc ttcctgttcg gcctgctgca atacttcaag
    20101 cacgcggacg tcaccagcct cacgcagttc agcctcagcg gctactttgg cagctacctg
    20161 gacttctcct caccggagca tgaactgacc ggctatgaac tgtccctgtt cttcaccatc
    20221 ttcgtccttc ttcagttctg gaacatgttc aacgccaagg ctttcaatac gcaccagagc
    20281 gcctttgccc gcatgggcgc cagcatcggg ggcttcgggg tggtggctct gctcatcctg
    20341 gccgggcaat acctcatcgt caccttcggc ggcaagatgt tcaacgtggt gcccctgagc
    20401 tggacggact ggggcattat ctttgccggc acctccctcg tcctgtggtt cggggaactg
    20461 gctcgggcat tcacgccggg caaatccggc tcccgcccca gaaccgtccg ggagtaacct
    20521 cccgcgcatg acgcgaacgg cgatgccgcc agggaaatct tctttcaaca aaggagcccg
    20581 caggcgtgtc attcccagca tggacttgac acgcctgacg ggctctatct ccggttccgc
    20641 cgttttcctc ttctcgcttt cccttttttt tgccgggtgt aaaaaaacgg aagaggttcc
    20701 gcatgaaacg cccacgctta tttatgaaca tcccgtcacc atggatattc cggtgacggg
    20761 aagctgggtg ggccacctgg acggcgtgga caacgcctcc atcgtccccc agattacggg
    20821 ctatctgcaa acgcagaatt acgccaatgg cgctattgtg aagaaagggg aagttctctt
    20881 ccgcattgac gattccacgt tcagggacca ggaatccaaa gccaaagcca ccctggcgca
    20941 ggcgcaggcc cagcttcagc agttgaatta cgacgcggag atttacaagc ccctggccgc
    21001 ggagaacgcc atttccaaac agaaatacga ggacacgcgc ctctccgccc tggccgcgga
    21061 agcgcaggtg cagcaggctg aagcggccct gtccctggct gaaaaaaatc tttcctatac
    21121 ggtgctgtac gcgccttttg acggaatagc cggcatttcc aagacaaaca tcggcgacct
    21181 ggtcagcccg gaaagcggcc ctctcgccgt cgtttcctcc gtcaatccca tccgcgtcaa
    21241 tttcgccgtc acccagcagg aatggattca gcaggcggga aagaacggga atgaaggcgt
    21301 ccagacgggc agcaagctgg acatcacgct gaaagacggc accaaatacc cggaacaggc
    21361 cacggtaaca gccattgacc gggcgttcaa tccccagaca ggcaccatcc gcgtacaggc
    21421 cgaccttccc aatgcggact acctgctgcg ccccggcatg ttcatcatcg ccacggcccg
    21481 gctggctacc gtcaaaaacg cgctgaccgt tccggcaaaa tcccttcttt caacacaggg
    21541 gcgctttttc gttattgttc tggacgagag cagccaccct tccatcatcc ccgtacaggc
    21601 cggaacgcag cttggagacc ggcagcaggt tattcccctg aaaccggatt ccctcacccc
    21661 ccaaagcaaa gtggtcgtgg acggacttct ccaggcggaa gcagcctcca gaaatccggc
    21721 cgcccgcctg aaagcggtac cctccagcaa ccaataagcc cctcccgcca tggctgattt
    21781 cttcatcaag cgccccatcc tttccatttg cctctccgtc atcatcgtcc tgctgggggc
    21841 cttttccatt ctgcgcctgc ccatatccga gtacccggac atcattcccc cctccatcca
    21901 ggtgacggcc acttatcccg gagcggactg tgaaacggtg gtcaagtcta tcgcatcccc
    21961 catcgaacag caaatgtccg gcgtggacgg catgtcctac atgacttccg tcaacaccaa
    22021 caacgggcaa atgagcatga tgatcctttt tgaaatcggc acggaagcca acatggacca
    22081 ggtgctttcc tacctgcgct acgggcaggc cacctcccag ctgccgtcgg aagtcagcgc
    22141 actgggagtc tcccttcgca agacaagcgg gctgcccgcc ctggtcgtca gcctctattc
    22201 cccccagggg acttatgacg gcctctggct ggccaattac gcctatatca atatggtgga
    22261 cgccatcaag cgcgtgcccg gagtaggaga cgtgcaggtg ttcggggcag gccgctacgc
    22321 catgcgcatc tggctgaacc cggaaaagat ggccgccctg aatattacgg cccgtgacgt
    22381 gatgctggcc gttcaggccc agaacgccgt aaatcccgcg ggcaagatag gcgcgcagcc
    22441 cgccccgccg gatcagcagc tttccttcac cgtaaaagcg cccggacgcc tgaccagcgt
    22501 gaaggaattc gaaaatatcg tggtgcgcgg gcaggacagt tccatcgtaa gagtgggaga
    22561 tatcgcccgc gtggaactgg gctcggaaac ctacagcctc agttcttccg taaacggcat
    22621 gcccgccgct tccatcggca tttacgaagc gcccggagga aatgccatcc agctggtgga
    22681 caatatcaaa gacctgctga aaaatacgga tatgccgccc ggcatggatt acctcgtttc
    22741 cctggactcc acgctggccg tccgtgccgg gattgaagac atcgtcagca cgctggtgat
    22801 tgccctggga ctggtgatgc tggtggtttt cattttcctc cagggctggc gcggcacgct
    22861 gattccggcc tttgccgttc cggtatctat cgtgggcgct ttcatcg
//
