LOCUS       c00033_gnlPro..        22854 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EHILBAHL_33.
ACCESSION   c00033_gnlPro..
VERSION     c00033_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:19:56
            Original ID  :: gnl|Prokka|EHILBAHL_33
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22854
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22854
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2808:12854]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2809..12854
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..22854
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22854
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             2..187
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 58.8; E-value:
                     1.2e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_1"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.3e-18, bitscore:
                     58.8, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GKVVSLDVAAGASVKAGDQILTLEAMKMNTIIYAPASGTLTAFCV
                     NPGDTVQEGQALAKIG"
     CDS             266..1930
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OAD_beta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_2"
                     /sec_met_domain="OAD_beta (E-value: 5e-159, bitscore:
                     521.0, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLFDSLITFLQGMGIFSLSWQMVGMWGIAILLLYLGVAKQYEPL
                     LMVPIAFGALIANIPDNGMLITQLNQQVISSNEQGEVTSTSLNNVGYLRVHVAPLQQTP
                     AKVPANLTTPEARAQYLETMQQPMQVYPGSQLTVSKIKSVRESQEKAKADAARLGDDSL
                     TVDPNLKDFQNVTEDNGNEPVFLLTNGEGTTVVRQQGVNYFDTSGNRVPVDLKTQKLEP
                     LVVSAAGKYVAVGQHTQELLVTSIHGGLYDWIGLGIKAEIFPPIIFLGVGALTDFGPLL
                     AAPRTLLLGAAAQVGVAATFFMALFMGFNPNEAASIGIIGGADGPTSIFLTMKLAPHLL
                     GAVAVAAYTYMSLVPLIQPPIMALLTTKKERLIRMKSLRTVSKSEKLFFAVLVTIVTIL
                     LIPDASPLIGMLMLGNFLRECKVTERLVQASQNEIINIVTIFLGTSVGLTMQGDRFLQA
                     ETLLIILLGIVAFGVATAGGVIAAKLMNLIWRKNPVNPLIGSAGVSAVPMAARVSHNVG
                     QKYDPSNYLLMHAMGPNVAGVIGTAVIAGYYIATLAK"
     CDS             1968..2747
                     /locus_tag="ctg33_3"
                     /transl_table=11
                     /translation="MNSAASFSTPPEEEGPCGDWTYHEWAEAFSTNDLARSLPPGHIAV
                     CRVQTGGRGRFNRKWIGEEGGLWASFTVPLSAPADTAAGVHWGHLPLVAGLALFNMLRG
                     MGLDSVRLRWPNDLLAGKSKLAGILVERPAENMAVIGIGINVFNDVASIAGEIKDPPAR
                     LADLVRNCPSLHAVMASLGSHLNQVLSVFSHGGIPALQEGLARAWAGERPVSILTDDET
                     VRGIFTGIDDQGNPVLSLPAGAVRTIPAHLINRLLEE"
     CDS             2809..4305
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: AcetylCoA_hyd_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: AcetylCoA_hydro"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_4"
                     /sec_met_domain="AcetylCoA_hyd_C (E-value: 3.8e-46,
                     bitscore: 148.9, seeds: 181, tool: rule-based-clusters)"
                     /sec_met_domain="AcetylCoA_hydro (E-value: 8.1e-43,
                     bitscore: 138.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYKVLTPEEAASLIKHGHHIGLSGFTPAGTAKAVTAALAKIAEA
                     EHEKGNPFQVSVFTGASTGDSCDGILSRAKAIRYRAPYTTNVDFRKAVNNGETAYNDIH
                     LSQMAQEVRYGFMGNVDIAIIEACEVTADGKIYLTAAGGIAPTICRLADKIIVELNAAH
                     SKSAMGLHDVYEPLDPPYRREISIFKPSDRIGKPYIQVDPKKIVGVVETNWPDEARSFA
                     AADPLTDKIGQNVADFLAADMKRGIIPSTFLPLQSGVGNIANAVLGALGRDKTIPAFEM
                     YTEVIQNSVIGLIREGRVKFGSACSLTVTNDCLEGIYRDMDFFRDKLVLRPSEISNSPE
                     VIRRLGVISINTAIEADIYGNVNSTHIGGTKMMNGIGGSGDFTRNAYISIFTCPSVAKD
                     GKISAIVPMVSHHDHTEHDVNIIITEQGVADLRGKSPKERAQTIIENCVHPDYKNILWD
                     YLKLSDGKAQTPQSIRAALGMHAELARSGDMKNVDWAQYK"
     CDS             4424..5125
                     /locus_tag="ctg33_5"
                     /transl_table=11
                     /translation="MNWMIYPAARAFIKVCAVLFGAGATAAALIHLFIPFFLRSPRTAA
                     PFLLLGTGAELLSILSLSFLMFWGARVLLASRGSKITRNLSMLAFLPALYALLIPFAGM
                     PASSQYTEMDRVWEAFLLLASVISFFSFPYTAGYGAAGRRLFLAWGISAAGCGLQSALF
                     FLAVLLRQFLTTAVPSLAAPVAWLAVLLSCGLEIMLAALSVILARRLFKNVMSIASMPE
                     PMDPAMPGNRP"
     CDS             5243..5437
                     /locus_tag="ctg33_6"
                     /transl_table=11
                     /translation="MKGFYGLEQTTSGNFRRHGHRMESIAGKQTAPSPENQGICRVVPS
                     ISLADLRQPYFTNSSKYRP"
     CDS             complement(5404..6267)
                     /locus_tag="ctg33_7"
                     /transl_table=11
                     /translation="MKGIVLAGGSGTRLHPVTLSVSKQLLPVYDKPMVYYPISVLMLAG
                     IREILIISTPRDLPLYRDLLGDGSRFGVSFEYREQPRPEGLAQAFIIGEEFIGKDSVAL
                     VLGDNIFYGRGLTEKLRRAAKLTSGATIFGYQVHDPQRFGVVEFNEEGKAVSIEEKPLR
                     PKSDMAVTGLYFYDNRVVEIAKRIPKSSRGELEITSVNQEYLKQGLLRVEKLARGYTWL
                     DTGTHDTLLEASMFVRTLEHHQGFKMACLEEIAFNNGWISPETLRSQAGAMNNNGYGRY
                     LDELVK"
     CDS             complement(6277..7329)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_8"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.2e-98, bitscore:
                     322.7, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVIVTGGAGFIGSNLVRLLLERGHEVLNIDALTYAGNIHSLDGS
                     ADSPAYRFLHADVRDASLMRRTLREYAPDWVMHLAAESHVDRSIDDPGNFMTTNVMGTF
                     SMLQAALEYYRSLEGEKKERFRFHHISTDEVYGSLGKEGLFTESTPYRPHSPYSASKAS
                     SDHLVRAWHDTYGLPVLITNCSNNYGPYQFPEKLIPVVILKALGGDPIPVYGKGENVRD
                     WLYVGDHCEALLKVVSCGKPGETYNIGGNNEKTNLELVELLCSHLDELRPRTDGRSYRE
                     QITFVQDRPGHDLRYAIDASKIRRELGWAPRQDHSSGFRKTIQWYLDHEEWWRGILSGE
                     YRLERLGTNG"
     CDS             complement(7461..8423)
                     /locus_tag="ctg33_9"
                     /transl_table=11
                     /translation="MSGIAIMISGGDAAGMNPAIKAAVDHARQLGMNPYVVYDGLEGLI
                     DGKIKEATRELTSDMIYRGGTLLRSSRSKRFFDYEFRRQAYEHLKERNIDKLIIMGGDG
                     SFRALNDFFNDFEVPFAGIPATIDNDIAGTDYCLGVDTAQNVILDCIDSVRDTARSHHR
                     AFVIETMGRDCGYLAMTTALCSAADICIVPEIPYDLESIYKRLQPVINEEGSCIIAVVA
                     EGTRVAQYLTRWLTERAGMDTRLTVLGHVQRGGSPTARDRLMGTRFATRAVEALNNGDI
                     NQIMVYHDGQYGYASLDSVAGQQYSVNQDIINLCRELSC"
     CDS             8534..9265
                     /locus_tag="ctg33_10"
                     /transl_table=11
                     /translation="MNDTAAAILKATAALRDGTERLRFGAPVHVTYNPLAYAWNPHEQY
                     VRTYGNGEKGHLFLGMNPGPFGMAQTGVPFGEVDAVVNWLHIRGEVGRPEHTHPKRPVE
                     GFGCPRSEVSGRRLWGLFAEAFGTAENFFRHNYVANYCPLIWMGATGANITPDKLPAEQ
                     RAAVDAVCMEHLLSLITILNPHTLVGVGAYATQKLRDAASRLPGKNFTIGTLLHPSPAS
                     PIANKLWPERPIQQLKELGIL"
     CDS             9603..11069
                     /locus_tag="ctg33_11"
                     /transl_table=11
                     /translation="MAISDYIVTIGLEVHCQIKTKSKMFCSCETGFGFEPNTRVCPTCL
                     GLPGALPVLNEFAIERTLLTGLMLGCSSPEISQWDRKNYFYPDMAKNYQTSQLDLPLCL
                     GGEVPLYPWSYPNDVIKAGVPPFRTVKLTRIHLEEDAAKITHHANYSLIDYNRAGSALM
                     EIVSEPDIDTPEEAYAYLKSLQQILNYGDISDADMEKGQMRCDVNISLRPHGQKELGAK
                     VEMKNINSMSAVRRALHYEIRRQAEELDMGIPQIQSTRRWDDERGESVVMRTKEDAHDY
                     RYFPCPDLVPVRTAPLVEKVRGQIPELPQERQKRFMEEYGLSEYDANVLVGDLELARFF
                     EEAAQGTASGKKIANWVINNISAVLNEKGMRPSECPVKPGAIRELIAIIDDGTVSNNQA
                     KDVFAKMWDEPALAAAQAAKLLGFEKADSSFLDGIVREVISANPDKVAEIQGGNEKLLN
                     WLTGQVMKAAKGKANPKIVTEALKKSLSME"
     CDS             complement(11124..12854)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_12"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.7e-34, bitscore:
                     109.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYRVADQVVEILEKAGIKRIYGIVGDSLNPVTDALRRRKTIEWIH
                     VRHEEAAAFAASAEAQLSGNLAVCCGSSGPGNLHLINGLFDAHRNHAPVLAIASHIPQS
                     QVGMEYFQATHPEQLFKECSAYAELVSDASQAPGILMSAIQHAWARRDVGVVVLPGDIA
                     DAPAEMKNLVHPPSYTRENVVPEHESVSLLARMLDDHRRITFFCGAGCAGAEDKVVRLA
                     HRLKAPIAYTWRGKDYFEHDNSLGIGMTGLLGWGDAYKAMHESDMIVLWGTDFPYFNFI
                     PTKPEIVQIDRRGEVLGRRCRLDLGICGDVSVTAEALLNMVQEKTDSEHLDASLKRHAR
                     DVRDMNAYMEGSDKESPIRPEQLTTALNKHAASDAVFTVDTGTPCIWSARFLCATPGRR
                     TLASFNHGSMANAMPMAIGAQMEFPGRQVIALCGDGGLSMLLGDLITIVQYRLPVKIVV
                     YNNDCLDFIQLEMQAAGLIPWQINLNNPSFAAVADAVGIKGFLLDKSSQVDQMVDMFLN
                     YPGPALLDAHVDRDAIALPPYISMGQAADFSLAMMKQTLAGEVKQVWNTLAGNRKLFKP
                     "
     CDS             12995..13417
                     /locus_tag="ctg33_13"
                     /transl_table=11
                     /translation="VNLRFSGGKLSETAAAHHQNGQAQDSQRSRGRFRNLKPGKTGNPF
                     RAKCFIRPFNFTPCKVGINPARNGIAVAVHVAVVGQRVKQRTINIDIHRLALVCARDGQ
                     SNVKKASIQNNGSFRNISTVLSKRPVRSIQVSISHA"
     CDS             14254..16764
                     /locus_tag="ctg33_14"
                     /transl_table=11
                     /translation="MATLLGCLPTSPAEVAFPGPAPGTASAEQSASGYTLSNNILTAKF
                     ILRNGSLSFGGMTSRLGPIAKAGGDLFIINLQDGRSIKSSDLKAGNVKFIALQPNPKAF
                     RLADRFPGKAVSATFQALNGTLRISWRAVLRDHSHYLRQELRLASTKPIQMKNIIAMQY
                     DLVEGKAGAPSVSGNARGALIVNDLAFAALETPMGINTVGSAGNMEGGETAIWSADKWS
                     TASWTGNFNVPQELKKQYGEQVSSAEGPVSIDGKGACTVTFQYKGGDKGNNKLNLAGVQ
                     LLSSRGAVLDSDFHNGSTGDSNADNTYTVQVPSKGNYILRYWAQTKSEPIASKGEITFS
                     LPVKTLEEKQEAQAGESRLAQGLWSRKTTMQPGEIWDVSSVLGIFAPGQKRRSFLAYME
                     RERVMPYRPFIHYNSWYELNINRNNDSDPAKRMTEEQCLAVLKDWQEQFFQKRGMSIDA
                     FVWDDGWDEFNSLWDFHKMFPQGFKRIDAAAGRQKAGIGTWLGPVGGYGASKGKRLAYW
                     NVKHPDNKIGNFQLSNKEYFDAFVGRCSQMVKDYNMKYFKFDGISTHFHAKGPGNEEDA
                     EGIIRVLNALRKKKGDLYINCTVGTWASPFWFRYADSVWRQENDFGTIGAGDNRDKWIT
                     YRDRLVHEVFVQGSPLMPINSMMTHGLMVTKFGPPACMPRDPENVKKELRCATACGTSL
                     QELYVDRDLMSANGGVLWDELAKGIKWIRRNADVLDDVHWVGGNPWNKETNEGAVYGWA
                     AWNKNKATLALRNSSDQEKSLTGTLRSILDIPANVKGSITFKDSYDDQRTLDGFSGNSV
                     NIDKELSFTLKPFEVLVYEGGKVK"
     CDS             complement(16872..17525)
                     /locus_tag="ctg33_15"
                     /transl_table=11
                     /translation="MWSDLSHGLSVLVDALAFLSRSWGFWVCAGSVTGLAAVYAWWRKR
                     LALWAFALAFLSLLAVVGLACRQEACQKTFLWIQEPELQALSGKYEVESSPRERWFFRP
                     PELKRFFQISSSTLLLNEDGTCEISSFPRPEAWGKWISRPEDRDDLSVLEEDLVSSCRG
                     TWSLVKKGGYYGVSIVYSPGSCLTLYLGGEEAECLVMPVNPDDPLEAVTFEKTF"
     CDS             17693..20464
                     /locus_tag="ctg33_16"
                     /transl_table=11
                     /translation="MKSAAHHQGLSEQQVLENRTKYGINILTPPEKDPLWKQFLEKFSD
                     PIIKILLVALFLSVGVAFYQFFTGTEPASVFLEPAGILAAILLATCVGFAFEVSANKKF
                     EILNQVNDDTMVQVIRGGNICELPRRDVVVGDIVILNTGEEVPADGILLEAVSLQVNES
                     TLTGEPLIGKTTNEAEFKKDATYPSNHVLKGTTVADGHGVMEVTSVGDRTEYGKVYEGS
                     QIDNKVQTPLNRQLSRLGDLITWASYAIAALIVIGRLTLYFSHLPGPVEWLSAGTFILN
                     TVMIAVTVIVVTVPEGLPMSVTLSLALSMKSMLANNNLVRKMHACETMGAATVICTDKT
                     GTLTRNQMNVYKADFYGLGNAAPAEDKLGNLIREGIAVNSTAFLDYSDPGHIKALGNPT
                     EGALLLWLHGLGVNYLDLRENARVLEQLTFSTERKYMATVAESPLLGKKVLYVKGAPEI
                     VLGLCSTVLTPEGLVPAADMRPSIEKQLLTYQNQAMRTLGFAYRILEDDAPVFEDGRII
                     RKDLVYLGIAAISDPVRDDVPQAVKDCMDAGIRIKIVTGDTPGTAREIGRQIGLWTEED
                     TPDRLMTGVEFEQTPDAELLDRVMDLKIMCRARPMDKERLVKLLQKKDQVVAVTGDGTN
                     DAPALNAAQVGLSMGDGTTVAKEASAITILDNSFMSISRAVMWGRSLYRNIQRFIVFQM
                     TINVAACLIVLIGAFLGTESPLTVTQMLWVNLIMDTFAALALASLPPDERVMQEPPRKT
                     TDHIITRPMGRNILGVGILFVAFLFGLLQYFKHADVTSLTQFSLSGYFGSYLDFSSPEH
                     ELTGYELSLFFTIFVLLQFWNMFNAKAFNTHQSAFARMGASIGGFGVVALLILAGQYLI
                     VTFGGKMFNVVPLSWTDWGIIFAGTSLVLWFGELARAFTPGKSGSRPRTVRE"
     CDS             20547..21704
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_17"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 1.1e-08,
                     bitscore: 27.1, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLTRLTGSISGSAVFLFSLSLFFAGCKKTEEVPHETPTLIYEHP
                     VTMDIPVTGSWVGHLDGVDNASIVPQITGYLQTQNYANGAIVKKGEVLFRIDDSTFRDQ
                     ESKAKATLAQAQAQLQQLNYDAEIYKPLAAENAISKQKYEDTRLSALAAEAQVQQAEAA
                     LSLAEKNLSYTVLYAPFDGIAGISKTNIGDLVSPESGPLAVVSSVNPIRVNFAVTQQEW
                     IQQAGKNGNEGVQTGSKLDITLKDGTKYPEQATVTAIDRAFNPQTGTIRVQADLPNADY
                     LLRPGMFIIATARLATVKNALTVPAKSLLSTQGRFFVIVLDESSHPSIIPVQAGTQLGD
                     RQQVIPLKPDSLTPQSKVVVDGLLQAEAASRNPAARLKAVPSSNQ"
ORIGIN
        1 cggcaaggtt gtttccctgg acgtggctgc tggcgcctcc gtgaaggccg gcgaccagat
       61 tctgacgctg gaagccatga agatgaacac catcatctac gctcccgcct ccggcacgct
      121 caccgctttc tgcgtaaacc cgggtgatac ggttcaggaa ggacaggctc tggccaagat
      181 cggttaatcc cggcggcaac cgcccggaac ctccaacagt tcctggctcc gactcagata
      241 acaaaccgct acaataacat tccgtatgag tctttttgat tcattaatca cctttttaca
      301 ggggatgggc atcttctccc tatcatggca aatggtaggg atgtggggca ttgccatcct
      361 gctcctgtat ctgggtgtag ccaagcaata cgaacctctc ctgatggttc ccattgcttt
      421 cggcgccctc atcgccaaca ttccggacaa cggaatgctc atcacccagc tgaaccagca
      481 ggtcatctcc tccaatgaac agggggaagt aacctccacg tccctgaaca acgtgggcta
      541 cctgcgcgtt catgtggctc ctctgcagca gacgcccgcc aaggtgccgg ccaatctgac
      601 cacgccggaa gcccgcgccc agtatctgga aaccatgcag cagcccatgc aggtttatcc
      661 cggcagccag ctgaccgttt ccaaaatcaa gtccgtgcgg gaatcccagg aaaaagccaa
      721 agctgacgcc gcccgcctgg gagacgacag tctgacggtg gatcccaacc tgaaggactt
      781 ccagaacgtg acggaggaca acggcaatga gccggtcttc ctgctcacga acggagaagg
      841 aaccaccgtc gtccgccagc agggcgtcaa ttactttgac accagcggca accgtgttcc
      901 cgtggacctg aaaacgcaga agctggaacc cctggtggtt tccgccgcag gcaaatacgt
      961 ggccgtaggc caacataccc aggaactgct ggtcacctcc atccacgggg gcctgtatga
     1021 ctggatcggg ctgggcatca aggctgaaat tttcccgccc atcatcttcc tgggcgtagg
     1081 agccctgacg gacttcggcc cgctgctcgc cgcaccgcgc accctgcttc tgggcgcggc
     1141 ggcccaggtg ggcgtagccg ccacgttctt catggccctg ttcatgggct tcaacccgaa
     1201 tgaagccgcc tccatcggca tcatcggcgg agctgacggc cccacctcca tcttcctgac
     1261 gatgaagctg gctccgcacc tgctgggcgc cgtggccgtg gccgcataca cgtacatgtc
     1321 cctggttccg ctgatacagc cgcccatcat ggcgttgctg acgaccaaga aggagcgcct
     1381 catccgcatg aaatccctgc ggacggtcag caagagcgaa aaactgttct tcgccgtgct
     1441 ggtaaccatt gtcaccattc tgctgattcc ggacgcatcc ccgctcatcg gcatgctgat
     1501 gctcggcaac ttcctgcgcg aatgcaaggt gacggaacgc ctggttcagg cctcccagaa
     1561 tgaaatcatc aacatcgtca ccatcttcct gggaacctcc gtgggtctca cgatgcaggg
     1621 agaccgcttc ctgcaggcgg aaacgctgct gatcattctg ctgggcattg tcgccttcgg
     1681 cgtagcaact gcgggcggcg tcatcgccgc caagctcatg aacctcatct ggcgcaagaa
     1741 tccggtcaac cccctcatcg ggtccgcagg cgtctccgcc gtcccgatgg cagcccgcgt
     1801 ctcccacaat gtgggccaga agtacgaccc ctccaactat ctgctcatgc acgccatggg
     1861 tccgaacgtt gcaggcgtga tcggcaccgc agtcatcgcg ggctactaca tcgccactct
     1921 ggcgaaataa ccagaattga aaattactcc cggcctcggc ccgtcccatg aattccgcag
     1981 cctcattttc cacccctccg gaggaggaag gaccatgcgg cgactggacc tatcatgaat
     2041 gggccgaggc tttttccacc aatgacctgg cccgctccct gcccccgggg catattgccg
     2101 tctgccgcgt tcagacagga ggccgcggca ggttcaaccg caaatggata ggggaggaag
     2161 gcggcctgtg ggcatccttc accgttcccc tgtccgctcc tgcggataca gcggccggcg
     2221 tgcactgggg ccatttgccc ctggttgcgg ggctggccct gttcaacatg ctccgcggca
     2281 tggggctgga ttccgtgcgc ctgcgctggc cgaacgacct gctggcgggc aaatccaaac
     2341 tggcgggaat actggtggaa cgcccggcgg aaaacatggc cgtcatcggc atcggcatca
     2401 atgttttcaa tgatgtagcc tccatcgccg gggaaatcaa ggaccctccg gcaaggctgg
     2461 cggatcttgt tcggaactgc ccttcgcttc atgccgtcat ggcttccctg ggcagtcatt
     2521 tgaaccaggt tctttccgtc ttttcccacg gcggcatccc cgctctccag gagggtctgg
     2581 cccgggcatg ggccggagaa aggccggttt ccattcttac ggatgatgaa accgtccggg
     2641 gcatttttac agggattgac gatcagggca atcctgtgct atcccttccg gccggcgccg
     2701 tccgcaccat tccggcgcac ctgattaaca ggctcctcga agaatgagcc tgccgctccg
     2761 tttttacacg gggtttcttt cttttttcat ccaacaaaaa tcactgacat gagttacaag
     2821 gtactgacac cagaagaagc agcaagcctg atcaagcatg gccaccatat tgggctgagc
     2881 ggattcacgc ccgccggaac ggccaaggcc gttacggccg cgctggcaaa aatcgcagaa
     2941 gcggaacatg agaaggggaa ccctttccag gtgagcgtct tcaccggtgc ttccaccggc
     3001 gattcctgcg acgggatcct ttcccgggcc aaggcaatcc gctaccgcgc tccctacacc
     3061 accaacgttg atttccgcaa ggcggtgaac aacggggaaa ccgcctataa tgacatccat
     3121 ttgtcccaga tggcccagga agtgcgctac gggttcatgg gcaacgtgga catcgccatt
     3181 attgaagcct gtgaagtcac ggctgacggc aaaatttacc tgacggccgc gggcgggatc
     3241 gctcccacca tctgccgcct ggcagacaaa attatcgtgg aattaaacgc cgcccacagc
     3301 aagagcgcca tgggcctgca cgacgtttac gaacccctgg atcctcccta ccgccgcgaa
     3361 atctccatct tcaaacccag cgaccgcatc ggcaagccgt acatccaggt tgacccgaaa
     3421 aagattgtgg gcgttgtgga aaccaactgg ccggatgaag cccgttcctt cgccgcagcg
     3481 gatcccctga ctgataaaat cgggcagaac gtggccgatt tcctggctgc cgacatgaaa
     3541 cggggcatca ttccctccac attcctgcct ctccagtccg gcgtaggcaa catcgcaaac
     3601 gcggtgctgg gcgccctggg ccgcgacaag acgattcccg cgttcgagat gtacacggaa
     3661 gtcatccaga actccgtcat cggcctgatt cgggaaggcc gcgtgaaatt cggcagcgcc
     3721 tgctccctga ccgtgacgaa cgactgcctg gaaggcattt acagggatat ggactttttc
     3781 cgcgacaaac tggtgctccg tccctcggaa atatccaaca gcccggaagt tatccgccgt
     3841 ctcggcgtca tctccatcaa caccgccatt gaagccgaca tttacgggaa cgtcaactcc
     3901 acgcacattg gcggcacgaa gatgatgaac ggcatcggcg ggtccggcga cttcacgcgc
     3961 aacgcctaca tctccatttt cacctgcccg tccgttgcca aggacggcaa gatcagcgcc
     4021 atcgtcccca tggtttccca ccatgaccat acggaacatg acgtcaatat cattattacc
     4081 gagcaggggg tcgcggacct gcgcggcaag agcccgaaag aacgggccca gaccattatt
     4141 gaaaactgcg tccacccgga ttacaaaaac atcctctggg attacctgaa gctgtccgac
     4201 ggcaaagccc agacgccgca atccatcagg gccgctttgg gcatgcacgc cgaactggcc
     4261 agaagcggag acatgaagaa tgtcgactgg gcccagtata agtaattccg catgccgtca
     4321 ctcgcattgg catccatgaa ttcacgttaa cccctcagga ccgcttccgc aaagggagcg
     4381 gtccttttcc ttttttctat cccctctact ccttttcttc accatgaact ggatgattta
     4441 cccggcagcc agggctttca tcaaagtctg cgccgttctt ttcggcgcgg gcgcaacagc
     4501 agcagccctc atccatctgt tcataccttt tttcctccgc tctccccgga cagccgcgcc
     4561 cttcctgctt ttgggaacag gggcggaatt gctctccatc ctttccctgt ccttcctcat
     4621 gttctggggc gccagagttc tgctggcctc ccggggaagc aagataacaa gaaatctgag
     4681 catgctggcc ttcctgcccg ccctgtacgc cctcctcatt ccgtttgcgg gcatgcccgc
     4741 ctcatcgcaa tatacggaaa tggacagggt ttgggaggcc ttcctccttc tggcgtccgt
     4801 catttctttc ttttccttcc cttatacggc gggatacggc gccgcaggca ggagattatt
     4861 cctggcctgg ggcatctcgg cggcaggatg cggtttgcag agcgccctgt tttttcttgc
     4921 cgtcctgttg cgtcaattcc tgaccacagc agttccctcc ctggcagcgc cagttgcatg
     4981 gctggccgtt cttttgtcct gcggcctgga aatcatgctg gcggcccttt ccgtcattct
     5041 ggcgcggcgc ctgttcaaaa atgtcatgtc catagcgtcc atgccggaac cgatggatcc
     5101 cgccatgccg ggcaaccgtc cctgactttc ccccctgcct tcatgtttac agccagttgg
     5161 aaggggttat cccccagtcc gcggcatgaa tacgtgaacc actcacggca gccttcttcc
     5221 aacccggctg ccgcctcccg gcatgaaagg cttttacggc cttgagcaga caacgtccgg
     5281 aaatttccgc cggcacggcc accgcatgga aagcatcgcc gggaagcaaa ccgccccctc
     5341 ccccgaaaac caagggattt gcagggtcgt cccttccatt tcccttgctg acctcagaca
     5401 gccctatttc accaattcat ccaaataccg cccataaccg ttattgttca tggctccggc
     5461 ctgggaacgc agcgtctccg gggaaatcca gccgttatta aaggctatct cctccaggca
     5521 cgccatcttg aacccctggt gatgctccaa cgtgcgaacg aacatggaag cctccagaag
     5581 ggtatcgtgc gtgcccgtat ccagccacgt atagccgcgc gccagctttt ccacgcgcaa
     5641 caggccctgc ttcaggtatt cctgattcac ggaggtaatt tccaactcgc cccgggagga
     5701 cttgggaatc cttttggcta tctccaccac ccggttgtcg taaaaataga ggcccgtcac
     5761 cgccatgtcc gatttgggcc tgagcggttt ttcctcaata gataccgcct tcccttcctc
     5821 attgaattcc actaccccga aacgctgcgg gtcatgcacc tggtacccga aaatggtcgc
     5881 tccgctcgtc agtttggcgg cccgcctcag cttctccgtc aggccgcgtc cgtaaaaaat
     5941 attgtccccc agcaccaggg ctacggaatc ctttccgatg aactcctctc caataataaa
     6001 ggcctgcgcc agcccctccg gcctgggttg ttccctgtat tcaaaggaga cgccgaacct
     6061 gctgccgtcc cccagcaaat cccggtacag gggcaggtcc cggggcgtgg aaatgatgag
     6121 gatttcccgt attccggcca gcatcagcac ggagatggga taataaacca tcggcttatc
     6181 gtaaacgggc agcaattgct tgctgacgga aagcgtaacg ggatgcagcc gcgtgccgct
     6241 tcccccggcc agaacaatac ctttcatatc aacctcctag ccattggttc caagacgttc
     6301 caggcggtat tccccggaca ggatgccccg ccaccattcc tcatggtcca gataccactg
     6361 aatggtcttt ctgaatccgg aagaatggtc ctggcgcgga gcccatccca attccctccg
     6421 tattttggaa gcgtcaatcg catagcgcag gtcatggccc ggcctgtcct gaacaaaggt
     6481 gatttgctcc cggtagctcc ggccgtccgt tcgcggccgc aattcatcca gatgggaaca
     6541 cagcagctcc accagttcca gattggtctt ctcgttattg ccgccgatgt tgtacgtctc
     6601 tccgggtttt ccgcaggaaa cgaccttcag cagcgcctcg cagtgatccc ccacatacag
     6661 ccaatccctc acgttttccc ctttgccgta tacagggatg gggtccccgc ccagcgcttt
     6721 caggataacg acggggatca gcttttccgg gaactggtaa gggccgtaat tgttggaaca
     6781 gttggtgatc agcacgggca gcccgtacgt atcgtgccag gcgcgcacca ggtggtcgct
     6841 ggaagccttg ctggcggaat acggggaatg ggggcgatac ggcgtggact ccgtgaacag
     6901 gccttccttt cccagggagc cgtacacttc atccgtggaa atgtggtgga agcggaaacg
     6961 ctcctttttc tctccctcca gggaacggta atattccaga gcggcctgaa gcatggaaaa
     7021 agtgcccatg acgttggtgg tcataaaatt tcccggatcg tcaatggaac ggtccacatg
     7081 ggattccgcc gccaggtgca tcacccagtc cggagcgtac tcccgcaaag tgcgccgcat
     7141 cagggaagcg tcccggacgt cggcgtgcag aaagcggtat gccggagaat ccgccgagcc
     7201 gtccagggaa tggatgttgc cggcataggt cagggcgtca atattcagga cttcatggcc
     7261 gcgctccagc agcagcctga ccagattgga gccgatgaat ccggcgccgc ccgtaacgat
     7321 aactttcata gcactgtttt cagggaaaga tgcggcgtca tcatacagca acggtgtttt
     7381 ttttcaaaac aaatccgccc atgccgcggg aacgtggcgg catgggcggg aaaaagcggg
     7441 ttccgtaacc gctgagacgg ctagcagctc agctcccggc aaaggttgat gatatcctgg
     7501 ttcacggagt actgctgccc ggcaacggaa tccagggagg catagccgta ctggccgtca
     7561 tgatacacca tgatctggtt gatgtccccg ttgttcagag cttccacggc gcgggtggca
     7621 aaacgggtgc ccatcaggcg gtcacgggca gtgggggaac cgccgcgctg cacatggccc
     7681 agcacggtca ggcgggtatc catgccggcg cgttccgtca gccagcgggt caggtactgc
     7741 gccacgcggg tgccttccgc caccacggca atgatgcagc ttccctcctc attgatgaca
     7801 ggctggaggc gcttgtaaat ggattccagg tcatacggaa tttcagggac aatgcagatg
     7861 tccgccgcgc tgcaaagagc ggtggtcatc gccagatagc cgcagtcccg gcccatcgtt
     7921 tcaatcacga aagcgcggtg atgggaacgg gccgtatcac ggacggaatc aatgcagtcc
     7981 agaatcacgt tctgggccgt gtccacgccc aggcagtagt ccgtaccggc aatgtcgttg
     8041 tcaatcgtgg ccggaatacc ggcaaaaggc acttcaaaat cattgaaaaa gtcgttcagg
     8101 gcgcggaaag agccgtctcc gcccataatg atgagcttgt cgatgttgcg ttccttcaga
     8161 tgctcgtagg cctgcctgcg gaattcgtag tcgaaaaagc gcttggaccg tgaggaacgg
     8221 aggagagttc cgcccctgta gatcatgtcg ctggtcagct cccgggtagc ttccttgatt
     8281 tttccatcaa tcagtccttc caaaccgtca taaacaacgt acggattcat tccaagctgg
     8341 cgggcatggt ccactgccgc cttgatcgcc gggttcattc cggcggcgtc gccgccagat
     8401 atcataatgg ctattccact cataagtaat aaggttaact tgtccggggg gaaatgttac
     8461 cgggcggaac aaataatgca agcgcggagt ttttactggc gcaataaacg gcaacgcttc
     8521 atgatgcgga ggcatgaacg acactgcagc agccattctg aaagccacgg ccgccctccg
     8581 ggacggcacg gaacggctcc ggttcggagc tccggtccat gttacctaca atcctcttgc
     8641 ttatgcatgg aacccgcatg aacagtatgt gcgcacctat ggaaacgggg aaaagggcca
     8701 tttgttcctg ggcatgaatc ccggcccctt cggcatggcc cagacgggcg tccccttcgg
     8761 ggaagtggat gccgtcgtca actggctgca catccgcgga gaggtggggc ggccggaaca
     8821 tacccatccc aaacgtcccg tggaaggctt cggctgcccc aggtcggaag tcagcggccg
     8881 ccgcctttgg ggacttttcg cggaagcttt cggcaccgcg gaaaacttct tccggcacaa
     8941 ttacgtggcc aattactgcc cgctgatttg gatgggcgcc accggggcca acatcacgcc
     9001 ggacaaactg ccggcggaac agcgcgccgc cgtggacgcg gtatgcatgg agcacctgct
     9061 ttccctcatc accatcctga atccccacac gctggtaggg gtgggagcct acgccacgca
     9121 gaaactgcgg gacgccgcct cccggctccc cggcaagaac ttcaccatcg gcacgttgct
     9181 ccacccaagc cccgccagcc ccatcgccaa caaactctgg ccggaacgcc ccatccagca
     9241 gcttaaggaa ctgggcattt tataaagaat ggggaggtta gagcggagag ttccgtgaca
     9301 tgaaaggaat caccgaagca acaagccgga aatttgcggt tcatgttgtt cacctgcggc
     9361 aattcccgcg ccacggcggg agcgggcccg tgttttcaaa caatgattga gacgcggcgc
     9421 cggcgtcacc ggggcggaga aggacataaa cgcctccccg cctccattgc aaaaacagcc
     9481 ttccgccaga ccaatcatca tctttagccg gaaaaccctc cgctctcccc cgcaggcctt
     9541 tttactggac agggagaaaa gggttccgta cagtttccgc gatcttcaag cgttccgaat
     9601 ttatggcaat ttcagattac atcgtgacca ttggcctgga agtccactgc cagatcaaga
     9661 caaagagcaa aatgttctgc tcctgcgaaa ccggctttgg ctttgaaccc aatacgcgtg
     9721 tgtgccccac ctgcctgggg ctgccgggcg ccctgcccgt cctgaatgaa ttcgccattg
     9781 aacgcacgct gctgaccggc ctgatgctgg gatgttccag cccggagatt tcccagtggg
     9841 accgcaagaa ttatttctat ccggacatgg ctaaaaatta ccagacctcc cagctggatc
     9901 ttccgctgtg cctgggaggg gaagtgcccc tgtacccctg gtcctatccg aatgacgtga
     9961 tcaaagctgg cgtcccccct ttccgcaccg tgaagctgac ccgcatccac ttggaagaag
    10021 acgctgcgaa gattacccat cacgccaatt attccctgat tgactataac cgcgcgggat
    10081 ccgccctgat ggaaatcgtt tccgagccgg acatcgacac cccggaagaa gcctatgcct
    10141 atctcaagtc cctccagcag attctgaatt acggggatat ctccgatgcg gacatggaaa
    10201 agggccagat gcggtgcgat gtgaatattt ccctgcgtcc tcacgggcag aaagaattgg
    10261 gcgccaaggt ggaaatgaag aacatcaact ccatgtccgc cgtccgcaga gcccttcatt
    10321 atgaaatccg gcgccaggcg gaagaactgg acatgggcat tcctcaaatc cagtccaccc
    10381 gccgctggga cgacgaacgc ggagaaagcg tcgtcatgcg taccaaggaa gacgcgcacg
    10441 attaccgtta tttcccctgc ccggatctgg ttcccgtacg cacggctccc ctggtggaga
    10501 aggtgcgcgg acagattccc gagctgcctc aggaacggca gaaacgcttc atggaggaat
    10561 atggcctgag cgagtatgac gccaacgtgc tggtggggga cctggagctg gcacgctttt
    10621 ttgaagaggc ggcgcaggga accgccagcg ggaaaaaaat cgccaactgg gttatcaaca
    10681 atatttccgc cgtgctgaat gaaaaaggca tgcggccgtc tgaatgcccc gtgaaacccg
    10741 gagccatccg ggagctgatc gccattattg acgacggcac cgtttccaac aaccaggcca
    10801 aggacgtatt cgccaaaatg tgggatgagc cggccctcgc cgcagcgcag gccgccaagc
    10861 tgctgggctt tgaaaaggcg gattcatctt ttctggacgg catcgtgcgg gaagttattt
    10921 ccgccaatcc ggacaaagta gcggaaatac agggcggcaa cgaaaagctc ctgaactggc
    10981 tcaccggcca ggtcatgaag gccgccaaag gcaaagccaa cccgaaaatc gtgacggaag
    11041 cgctgaaaaa atccctttcc atggagtgac cccaaacaaa gagccacgtc ttttaccggt
    11101 tcccggccct tgcccgcagg acatcacggt ttgaacagtt tcctgtttcc ggccagggta
    11161 ttccatacct gcttcacttc cccggccagc gtctgcttca tcatggcaag ggaaaagtcc
    11221 gcggcctggc ccatgctaat gtaaggaggc agagcaatgg cgtccctgtc cacatgcgcg
    11281 tccagcagag cggggccggg ataattcagg aacatgtcta ccatctggtc cacctggctg
    11341 gacttatcca ataaaaagcc tttgatgccg acggcatccg ctacggcggc aaaagagggg
    11401 ttgttcaggt tgatctgcca tggaatcagc ccggccgcct gcatttccaa ctgaatgaaa
    11461 tccaggcagt cattattata taccacgatt ttcaccggca gcctgtactg gacaatcgtg
    11521 atgagatccc ccagcagcat ggacaggccg ccatctccgc acagggcaat tacctgccgt
    11581 ccggggaatt ccatctgcgc cccaatggcc atcggcatgg cattggccat ggagccatga
    11641 ttgaaagacg ccagcgtcct ccttcccggc gtagcgcaca ggaaccttgc gctccagatg
    11701 cagggggttc cggtatctac cgtaaatacg gcgtcggatg ccgcatgctt gttcaaggcg
    11761 gtcgtgagct gttccggacg gatgggagac tccttatcgc ttccttccat ataggcgttc
    11821 atatccctca cgtccctggc gtggcgtttc agggaggcgt ccaaatgctc ggaatccgtt
    11881 ttttcctgca ccatgttcag caacgcctcc gccgtgacgg aaacatcccc gcaaataccc
    11941 agatccaggc ggcagcggcg gcccagcact tccccgcgcc tgtcaatctg cacgatttca
    12001 ggcttggtgg gaatgaaatt gaaatagggg aaatccgtcc cccacaatac gatcatatcg
    12061 ctttcatgca tggccttgta ggcatctccc catcccagca gccccgtcat gccgatgccc
    12121 agggaattgt catgttcaaa ataatccttg cccctccatg tgtaggcaat cggagctttc
    12181 aggcggtgcg cgagccggac gaccttgtct tccgctcccg cgcagccggc gccgcagaag
    12241 aaagtaatgc ggcggtggtc gtcaagcatc cgtgccagaa gggatacgga ttcatgctca
    12301 ggaacaacat tctcccgcgt gtaggaagga ggatgcacca gattcttcat ctccgcaggg
    12361 gcgtccgcaa tgtctccggg caagacgacg acgcctacgt cgcgcctggc ccacgcgtgc
    12421 tgaatggcgg acatcaaaat gcccggagcc tgggaagcat ccgaaaccag ttccgcatat
    12481 gcactgcatt ccttgaaaag ctgttccgga tgagtggcct ggaaatattc catacctacc
    12541 tggctctgcg ggatgtggga ggcgatggcc agcaccggag catgattccg gtgggcgtca
    12601 aacaatccgt tgatcaaatg gaggtttccg gggccgctgc tgccgcagca tacagccagg
    12661 ttcccgctca gctgggcttc cgcgctcgcg gcaaaggccg ccgcttcctc atgccgcaca
    12721 tgaatccatt caatggtctt cctccttctc aaagcatccg taacggggtt caggctatcc
    12781 cccacaatac cgtaaattct cttaattccc gccttttcca aaatttcaac gacctgatcg
    12841 gctaccctgt acatgcagat tagacaccgt ccaatctcca acggattcat tcttatgtgt
    12901 catcctcccg ccttttccgc accggaaaaa atatctgcgg ttatcttccc aatacaagaa
    12961 ataataaggc cgccgccttt tcaggcagcg gcccgtgaat ttacggtttt ccggaggaaa
    13021 actgtcagag acggcggcgg cgcatcatca aaacggccag gcccaggatt cccagagaag
    13081 ccgaggccgg ttccggaacc tgaagcccgg caaaaccggc aatccgttcc gcgccaagtg
    13141 tttcatccgt ccatttaact tcaccccatg taaggtcggg attaatccag ctcgtaatgg
    13201 gattgcggtt gccgttcatg ttgccgttgt aggccagcgt gtcaaacaga gaaccattaa
    13261 catagacatc cacagactgg ctctggtctg cgcccgtgac ggacaaagta acgttaagaa
    13321 ggcctccatt caaaacaacg gaagtttcag aaacatctcc acggttttga gtaaaagacc
    13381 cgttagaagt attcaagttt ccatctccca tgcctagctt ggcgtctgaa gtcagataca
    13441 aggcatttgc cccgtaattc tgagctgcgt tggttccata ataaccaaac agcgctgttt
    13501 gagttccttc cgttaaggaa gaggtatcca gccagaggga gatcgtgtaa ctggaagcat
    13561 aaaaattacc gccataaggg atggagttat taggaataga gctgtttgag aggctcccga
    13621 acgtcatatc ttttcccaat gcaactcctt cagttgtcgt cgtcgtaccg gaattgtaaa
    13681 gcgtttcgga ctccggagca acagagccgg gatccgccaa cgccggtacg gaacaacaca
    13741 ccgcaatggc cattgatgct aatgtttttt tcattttcta tgtatgatgg attgagctat
    13801 tagagagata ttccccgccc tctgtatatc ggattccaaa tccgttcttt ttctattcag
    13861 ccaagaaaga tgagaataag tttttccaat tctctaaata aatttttaat attcttattt
    13921 tctattactt acggataaaa ataaaacgca gaataaatgt tttttgtagc ggctccaaaa
    13981 ttgctgttta ggaacagaaa tccctttttt caaaatagaa aaaattgtaa taatattttc
    14041 atatctgaaa tgttaggttg accccggatt tggaatccgg ttgttttccc gcagccatca
    14101 aaaaagcaac ataagatttt catattcaat aaaaatcatt tttctttcac tccatttcca
    14161 ggaccttttt cttgaaaaag atccttcccc aaattatcct gccgctagct gtaatattat
    14221 ttcatcatga aatttttcaa aacacccctt gtcatggcaa ccctgctggg ctgcctgccc
    14281 acctctccgg cagaagttgc ctttccgggg cctgcccccg gaacagccag cgcggaacaa
    14341 tccgcttccg gctatactct ttccaataac atcctgacgg ccaaatttat ccttcggaac
    14401 ggaagtcttt cctttggagg aatgacttcc agactgggcc ccatcgccaa ggctggggga
    14461 gatttattca tcatcaatct tcaggacgga cggagcatta aatcctccga tctgaaagcg
    14521 ggaaacgtca agttcatcgc ccttcagccc aaccccaagg cattcaggct ggctgaccgc
    14581 tttccaggaa aagccgtcag cgcaacgttt caggccctga acggcaccct tcgcatctcc
    14641 tggcgcgccg tgctcaggga ccattcccat tacctccggc aggaactccg cctggcaagt
    14701 accaagccca tccagatgaa aaacatcata gcgatgcaat atgacctggt agaagggaaa
    14761 gccggggcac cctccgtctc cggcaacgcc agaggcgcac tcatcgtcaa tgacctggcg
    14821 ttcgccgccc tggaaactcc catgggcatt aataccgtgg ggagcgccgg aaatatggaa
    14881 gggggagaaa ccgccatctg gagcgcggac aagtggtcca cagcttcatg gacaggaaat
    14941 ttcaatgtcc cccaggagct gaaaaagcag tacggagaac aggtttccag tgcggaaggt
    15001 ccggtttcca ttgacggcaa aggagcatgc accgtcacct tccagtataa gggaggggac
    15061 aagggcaaca ataagctgaa cctcgccggc gtgcagcttc tctcttccag aggagccgtc
    15121 cttgactctg atttccacaa cggcagcacc ggggattcca atgccgacaa cacctacacg
    15181 gtacaggttc cctccaaggg aaattacatt ctgcgctact gggcccagac caagagcgaa
    15241 ccgattgcca gcaaggggga aatcaccttt tccctgcccg tgaagacgct tgaggaaaag
    15301 caggaagccc aggcgggcga atcccggctg gcccagggtc tctggagccg taaaaccacc
    15361 atgcagcccg gagaaatatg ggacgtatcc tccgttctcg gaatttttgc ccccggccag
    15421 aaacgccgct ccttcctggc ctatatggaa cgggaacgcg tgatgcccta ccgcccattc
    15481 atccattata attcctggta tgaactgaac atcaaccgca ataatgattc ggaccccgcc
    15541 aagcgcatga cggaagaaca atgcctggcc gtcctgaaag actggcagga acagtttttc
    15601 cagaagcgcg gcatgtccat tgacgccttc gtctgggatg acggatggga tgaattcaac
    15661 agcctgtggg atttccacaa gatgttcccg caaggcttca agcgcattga cgccgccgcc
    15721 ggccggcaaa aggccggcat cggcacgtgg ctgggtccgg tggggggcta cggagcctcc
    15781 aagggcaagc gcctcgccta ctggaacgta aagcacccgg acaacaaaat cggcaacttc
    15841 cagctctcca acaaggaata ttttgacgcc tttgtgggcc gctgctccca gatggtgaag
    15901 gactacaata tgaagtactt caaattcgac ggcatcagca cccacttcca tgccaagggg
    15961 cccggcaacg aggaggatgc ggaaggcatc atccgcgtgc tgaacgccct gcgcaagaaa
    16021 aagggggatc tttacatcaa ctgcactgta ggaacctggg catccccctt ctggttccgt
    16081 tatgcggatt ccgtatggag gcaggagaat gacttcggca ccatcggagc gggcgacaac
    16141 cgcgacaaat ggatcaccta ccgcgaccgc ctggtgcatg aagtttttgt gcagggctcc
    16201 ccgctgatgc ccatcaattc catgatgact cacggcctga tggtcactaa attcgggcct
    16261 ccggcatgca tgccccgcga cccggaaaac gtcaagaaag aactccgctg cgccacggcc
    16321 tgcggcactt ccctccagga gctatacgtg gatcgggacc tgatgagcgc caacggggga
    16381 gttctgtggg acgaactggc caaggggatc aagtggatac gccgcaatgc ggacgttttg
    16441 gacgacgtgc actgggtggg cggcaatccg tggaacaagg aaaccaacga aggggccgtg
    16501 tacggctggg ccgcatggaa taaaaacaag gccaccctgg ccctccgcaa ttcctccgac
    16561 caggagaaga gcctgaccgg taccctgcgc agcatcctgg atatccccgc aaacgtcaag
    16621 ggctccatca ccttcaagga ttcctatgac gaccagcgga cgctggacgg cttctccgga
    16681 aattccgtaa acattgacaa ggagctctcc ttcacgctga agccttttga agtgctggtg
    16741 tacgaaggag gcaaagtcaa atagaatcaa cagtctgtac gcccggccag aaccggaacg
    16801 gcgttggaaa aaacatgtag agggaggcgg tgcccccgcc tcccttcttt ttccgtccgg
    16861 aagaaccagg atcagaatgt tttttcaaac gttaccgctt ccagcggatc gtcaggattg
    16921 accggcatca ccaggcattc cgcctcttcc ccgcccaggt acagcgtcag gcagctcccg
    16981 ggggaataga caatggagac gccgtaatat cccccttttt tcaccaggga ccaggttccg
    17041 cggcaggagg aaacgaggtc ctcctccagc acggaaaggt catccctgtc ttccgggcgg
    17101 gaaatccact ttccccacgc ctccggacgc gggaaggagg aaatctcgca cgttccgtct
    17161 tcattcagga gaagcgtgga ggagctgatc tggaaaaagc gcttcagctc cggggggcgg
    17221 aaaaaccacc gctccctggg ggaggattcc acctcgtact ttccggacag ggcctggagt
    17281 tccggttcct gaatccacag gaaagtcttt tgacacgcct cctggcggca cgccaggccc
    17341 accacagcca acagggaaag gaaagcaagg gcaaacgccc acagagccag ccgctttctc
    17401 caccacgcat acacggcggc cagtcccgtc acgctgcccg cgcagaccca gaacccccag
    17461 gaacgggaaa ggaaggcaag ggcgtccacc aggacggaaa gtccatgaga aagatcactc
    17521 cacataggcg ctccagaatc tccggaatat tgtcaaagtc aagacaacaa tgccgccttt
    17581 taaggcacgg cgcgcagcct gcggcccgct aaaaaactcc cgtcatcacc cctgaaaatc
    17641 ttcctccgca cttttctcac gggctccaat caggtaaaga agcatctcaa ccatgaaaag
    17701 cgcagcacat catcaggggc tttcggaaca gcaggttctg gaaaaccgga ccaaatacgg
    17761 gatcaatatc ctgacacccc cggagaagga tcccctgtgg aagcaattcc tggagaaatt
    17821 ttcagacccc attatcaaga ttctgctggt ggccctgttc ctgtccgtag gcgtagcttt
    17881 ctaccagttt ttcaccggaa cggaaccggc cagcgtcttt ctggagcccg cgggcatcct
    17941 ggcggccatc ctgctggcta cctgcgtggg gttcgccttc gaggtaagcg ccaacaaaaa
    18001 gtttgaaatc ctgaaccagg tcaatgacga caccatggtc caggtcatcc gcggcggcaa
    18061 tatctgcgaa ttgccccgcc gggacgtggt ggtgggcgat atcgttatcc tgaacacagg
    18121 agaggaggtc ccggcggacg gcatcctgct ggaagccgtt tccctccagg tcaacgaatc
    18181 cacgttgacg ggggaacccc tcatcggcaa aaccacgaat gaagcggaat tcaagaaaga
    18241 cgccacttac ccctccaacc acgttctgaa aggaactacc gtggcggatg gccacggcgt
    18301 catggaagtg acgtccgtag gggacaggac ggaatacggc aaggtttatg aaggctccca
    18361 gatcgacaat aaggtgcaga cgcccctcaa ccgccagctt tccaggctgg gggacctcat
    18421 cacctgggcc agctacgcta tcgccgccct catcgtcatc gggcggctta ccctttactt
    18481 ctcccacctg cccggccccg tggaatggct gagcgcggga accttcattc tgaataccgt
    18541 catgatcgcc gtgaccgtca tcgtagtcac ggtgccggaa gggctgccca tgagcgtcac
    18601 cctgagcctg gccctgagca tgaagagcat gctcgccaac aataatctgg tgcgcaagat
    18661 gcacgcctgc gaaaccatgg gggccgccac cgtcatctgc acggacaaga cgggaaccct
    18721 gacgcgcaac cagatgaacg tatacaaggc tgatttctac ggcctgggga atgctgcccc
    18781 ggcggaagac aagctgggca atctgatccg ggagggtatc gccgtcaact ccaccgcctt
    18841 tctggattac tcggatccgg ggcatatcaa ggccttggga aatcccacgg aaggggcgct
    18901 cctcctgtgg ctgcacgggc tgggcgtgaa ttacctggat ttgcgggaaa acgcccgcgt
    18961 gctggaacag cttactttct ccacggaacg caagtacatg gccaccgtgg cggaatcccc
    19021 cctgctgggt aaaaaagtcc tttacgtgaa aggcgcgccg gaaatcgtgc tgggcctctg
    19081 ctccaccgtc ctgacaccgg aaggcctggt tcccgccgcg gacatgcgtc cctccattga
    19141 gaaacagctc ctgacctatc aaaaccaggc catgcgtacg ctgggcttcg cataccgcat
    19201 tctggaggat gacgccccgg tattcgaaga cggccgcatt atccgcaagg atctggttta
    19261 cctgggcatc gccgccattt ccgaccccgt ccgggacgat gtgccccaag ccgtgaagga
    19321 ctgcatggac gcgggcattc gtatcaagat cgttacgggg gacacccccg gcaccgcacg
    19381 ggaaatcgga cgacagatcg gcctgtggac ggaggaggac acgccggacc gcctgatgac
    19441 gggagtagag tttgagcaga ctccggatgc ggaactgctg gaccgcgtga tggatctgaa
    19501 aatcatgtgc cgtgccaggc ccatggataa ggaacggctg gtaaagctgc tccagaaaaa
    19561 ggaccaggta gtggccgtta ccggggacgg caccaacgac gcccccgccc tgaacgccgc
    19621 tcaggtgggc ctctccatgg gggacggcac taccgtagcc aaggaagcca gcgccatcac
    19681 catcctggac aattccttca tgagcatttc ccgcgccgtc atgtggggac gctccctgta
    19741 caggaatatc cagcgcttca tcgtcttcca gatgaccatc aacgtggcgg cctgcctcat
    19801 tgtgctcatc ggcgcgttcc tgggcacgga atcccccctc accgtcacgc agatgctctg
    19861 ggtcaacctc atcatggaca ccttcgccgc gctggccctg gcctctctgc cgccggacga
    19921 acgcgtgatg caggagccgc ctcgcaagac gacggaccac atcatcaccc gccccatggg
    19981 caggaacatt ctgggcgtgg gcatcctgtt cgtggccttc ctgttcggcc tgctgcaata
    20041 cttcaagcac gcggacgtca ccagcctcac gcagttcagc ctcagcggct actttggcag
    20101 ctacctggac ttctcctcac cggagcatga actgaccggc tatgaactgt ccctgttctt
    20161 caccatcttc gtccttcttc agttctggaa catgttcaac gccaaggctt tcaatacgca
    20221 ccagagcgcc tttgcccgca tgggcgccag catcgggggc ttcggggtgg tggctctgct
    20281 catcctggcc gggcaatacc tcatcgtcac cttcggcggc aagatgttca acgtggtgcc
    20341 cctgagctgg acggactggg gcattatctt tgccggcacc tccctcgtcc tgtggttcgg
    20401 ggaactggct cgggcattca cgccgggcaa atccggctcc cgccccagaa ccgtccggga
    20461 gtaacctccc gcgcatgacg cgaacggcga tgccgccagg gaaatcttct ttcaacaaag
    20521 gagcccgcag gcgtgtcatt cccagcatgg acttgacacg cctgacgggc tctatctccg
    20581 gttccgccgt tttcctcttc tcgctttccc ttttttttgc cgggtgtaaa aaaacggaag
    20641 aggttccgca tgaaacgccc acgcttattt atgaacatcc cgtcaccatg gatattccgg
    20701 tgacgggaag ctgggtgggc cacctggacg gcgtggacaa cgcctccatc gtcccccaga
    20761 ttacgggcta tctgcaaacg cagaattacg ccaatggcgc tattgtgaag aaaggggaag
    20821 ttctcttccg cattgacgat tccacgttca gggaccagga atccaaagcc aaagccaccc
    20881 tggcgcaggc gcaggcccag cttcagcagt tgaattacga cgcggagatt tacaagcccc
    20941 tggccgcgga gaacgccatt tccaaacaga aatacgagga cacgcgcctc tccgccctgg
    21001 ccgcggaagc gcaggtgcag caggctgaag cggccctgtc cctggctgaa aaaaatcttt
    21061 cctatacggt gctgtacgcg ccttttgacg gaatagccgg catttccaag acaaacatcg
    21121 gcgacctggt cagcccggaa agcggccctc tcgccgtcgt ttcctccgtc aatcccatcc
    21181 gcgtcaattt cgccgtcacc cagcaggaat ggattcagca ggcgggaaag aacgggaatg
    21241 aaggcgtcca gacgggcagc aagctggaca tcacgctgaa agacggcacc aaatacccgg
    21301 aacaggccac ggtaacagcc attgaccggg cgttcaatcc ccagacaggc accatccgcg
    21361 tacaggccga ccttcccaat gcggactacc tgctgcgccc cggcatgttc atcatcgcca
    21421 cggcccggct ggctaccgtc aaaaacgcgc tgaccgttcc ggcaaaatcc cttctttcaa
    21481 cacaggggcg ctttttcgtt attgttctgg acgagagcag ccacccttcc atcatccccg
    21541 tacaggccgg aacgcagctt ggagaccggc agcaggttat tcccctgaaa ccggattccc
    21601 tcacccccca aagcaaagtg gtcgtggacg gacttctcca ggcggaagca gcctccagaa
    21661 atccggccgc ccgcctgaaa gcggtaccct ccagcaacca ataagcccct cccgccatgg
    21721 ctgatttctt catcaagcgc cccatccttt ccatttgcct ctccgtcatc atcgtcctgc
    21781 tgggggcctt ttccattctg cgcctgccca tatccgagta cccggacatc attcccccct
    21841 ccatccaggt gacggccact tatcccggag cggactgtga aacggtggtc aagtctatcg
    21901 catcccccat cgaacagcaa atgtccggcg tggacggcat gtcctacatg acttccgtca
    21961 acaccaacaa cgggcaaatg agcatgatga tcctttttga aatcggcacg gaagccaaca
    22021 tggaccaggt gctttcctac ctgcgctacg ggcaggccac ctcccagctg ccgtcggaag
    22081 tcagcgcact gggagtctcc cttcgcaaga caagcgggct gcccgccctg gtcgtcagcc
    22141 tctattcccc ccaggggact tatgacggcc tctggctggc caattacgcc tatatcaata
    22201 tggtggacgc catcaagcgc gtgcccggag taggagacgt gcaggtgttc ggggcaggcc
    22261 gctacgccat gcgcatctgg ctgaacccgg aaaagatggc cgccctgaat attacggccc
    22321 gtgacgtgat gctggccgtt caggcccaga acgccgtaaa tcccgcgggc aagataggcg
    22381 cgcagcccgc cccgccggat cagcagcttt ccttcaccgt aaaagcgccc ggacgcctga
    22441 ccagcgtgaa ggaattcgaa aatatcgtgg tgcgcgggca ggacagttcc atcgtaagag
    22501 tgggagatat cgcccgcgtg gaactgggct cggaaaccta cagcctcagt tcttccgtaa
    22561 acggcatgcc cgccgcttcc atcggcattt acgaagcgcc cggaggaaat gccatccagc
    22621 tggtggacaa tatcaaagac ctgctgaaaa atacggatat gccgcccggc atggattacc
    22681 tcgtttccct ggactccacg ctggccgtcc gtgccgggat tgaagacatc gtcagcacgc
    22741 tggtgattgc cctgggactg gtgatgctgg tggttttcat tttcctccag ggctggcgcg
    22801 gcacgctgat tccggccttt gccgttccgg tatctatcgt gggcgctttc atcg
//
