LOCUS       c00015_gnlPro..        15245 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DCMOJNDA_15.
ACCESSION   c00015_gnlPro..
VERSION     c00015_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:38:59
            Original ID  :: gnl|Prokka|DCMOJNDA_15
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 57397
            Orig. end    :: 72642
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15245
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[67397:72641]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15244
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15245
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15245
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             854..2341
                     /locus_tag="ctg15_53"
                     /transl_table=11
                     /translation="MKKIQLFLLLFLLISITQHINAQFPVKTEYTVEMGGTSGKGTYAP
                     MWLTANRQGLSSVNTENGYLRAGIAHTMPLNQHFGFSAGLDLATAYNFTSSFIIQQAYA
                     DLSYRWLNLSIGSKERLPELKNSKLSSGGMVESNNARPIPQVRLEVPYYVAIPGTHKWL
                     YLKGHIAYGRFTDDKWQEHFTSIGNKYAIDVLYHSKSLFAKVGNKEHFPVEFEGGIQMS
                     AQFGGDQYIAGQKEPVIDMPTRFVDFMCVLVPMAGDDTTPEGEQVNIYGNHVGSWNFAA
                     TAYLNQWKVKIYYEHYFDDHSQMFFQYGRWKDGHIGLEITFPKNRFIDTFVYEGLGTKD
                     QTGPMLYDSFWGEFEEQISAKDNYYNHYLYQGWQHWGMGIGNPLLPGPIYNKNGQITFI
                     SNRVLAHHIGFCGSPCQSLSYRMLLSYSRHWGTYDNPLNEIKKQFNSLFEVTYAPQQLK
                     GWSFTVSGAMDRGSMLGNNYGGMLVIRKQGIIKSGNK"
     CDS             2400..2780
                     /locus_tag="ctg15_54"
                     /transl_table=11
                     /translation="MLGISSCDKAPINGKLDGRWQLMTIEYTNGKIEECNRIYYSIQLH
                     LVEISAKGGNGGTHIGRFSYKGDEVTMSEFRHRGDEEKLTTLNELKPFGLNQAINHLKV
                     EKATGKKLILKSDYARLTFRKF"
     CDS             complement(3000..4433)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_55"
                     /sec_met_domain="Lyase_1 (E-value: 5.9e-91, bitscore:
                     297.1, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 4.4e-25, bitscore:
                     80.0, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METKLTEETRVESDLIGAREIPASALYGVQTLRGIENFPISKFHL
                     NEYPLFINGLAITKMAAAMANYELGLLTKEQKDAIVLACQEILNGEHHEQFPVDMIQGG
                     AGTSTNMNANEVIANRALEIMGHKRGEYQYCSPNDHVNCSQSTNDAYPTAIHIGMYYSH
                     LRFLPYLESLIGAFHKKGEEFAHIIKMGRTQLEDAVPMTLGQTFNGFASILRDEIRHLN
                     EAAADFLTVNMGATAIGTGICAEPGYAEKCVEALCEITGFDFKLSSDLVGATSDTSCLV
                     GYASALKRVAVKVNKICNDLRLLASGPRCGLGEFNLPAMQPGSSIMPGKVNPVIPEVMN
                     QICYKVIGNELCVTMAGEAAQMELNAMEPVMAQCCFESVDLMVNGFETLRTRCVEGITA
                     NAERCKIEVHNSIGVVTALNPIIGYKNSTKIAKEALETGRSVYELVLEHGILNKEELDT
                     ILSPENMLKPVKLDIKPRR"
     CDS             complement(4697..5587)
                     /locus_tag="ctg15_56"
                     /transl_table=11
                     /translation="MDSVFITTRKQRVIRELRDYMLIALGMLMYAIGWTVFLLPNDLPS
                     GAVPGIASIVYWATGLPVQYTYLGINGVLLILSLVILGWKFSVKTIYAVFVLTSILPII
                     QDLTGGESLIHDQPFMACVLGAFFCGGGIGVAFSANGSTGGTDIIAAIVNKYRDITLGR
                     VILMCDLVIISSSYFVLHDWEKVVYGYVVLFISSFVLDQVVNSARQSVQFFIISKKHEE
                     IGHRINKDLHRGVTFIDGVGCYTGAGVKMMFVLAKKRESTTIFRLIKDIDPNAFVSQSA
                     VIGVFGEGFDRIKVK"
     CDS             complement(5728..7605)
                     /locus_tag="ctg15_57"
                     /transl_table=11
                     /translation="MKTKFWIICLSVFFVSCLRNMHDIYTGGGEEEEEKINKDDFFDFT
                     TVRNSQLIIDYGMKVQTAFYLYDEYPMELVENTWEFKDINPIYAASTDMNGRFFSKVSL
                     PAYLKKVWLVTDNVLVVSPVELELLSDGLTFNYVDYKAQLSADGRSRAVMGGVSYPDGY
                     DVLGNWNENGVPDYLLPEKLDIPGAFLERCSNLSRSIVVDNRNLLERFPELRTSGSNDM
                     VITKSTGLVATYFNFSSTTWEDMVAYYTYKEGESVDMATIKKTILIPRSSRNAPKSLVG
                     EQIKLKYWNKEQSKYEDEFPQGTHIGWILLGMGFGKEKGVFPRYSNPAYNDNKEQRSVL
                     LSDPELDNCFFMAMEDNVDMRFNDVQFAIMASASSSVEPTPNIPDEVNKGEISYVVKGS
                     LAYEDNWPDKNDYDMNDVVIYYSSTVVKDKSSNALVRTTTTFTPMNDGATYTNGFGFQL
                     DYVGKEHIDLVQVSQEGNVIGKNFEPGIEKPVLILFSDIKPVLKKPVTVVIGFKKYDKV
                     SDMDAYPPYNSFIFVNKRSHEVHLSGYKPTSVADESLRGTGSDLSQDSNGTPMYYIAED
                     NMPFAINISNSEFRWPSEKVSITTYYPEFKQWRDSFGADYKDWYLHPKE"
     CDS             7745..7843
                     /locus_tag="ctg15_58"
                     /transl_table=11
                     /translation="MQFFSLLYVLSNITTANQVFTYPRGVSGYLHL"
     CDS             complement(7897..8931)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_59"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.7e-52, bitscore:
                     170.9, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYDVVIVDNLSNSSADVVDN
                     IEKVSGIRPAFEKLDCLDFEGMDKLFTKYPGIKGIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIIFSSSCTVYGQPDVLPVTEEAPIKKAESPYGNTKQINEEII
                     RDTVASGSPINAIMLRYFNPIGAHPTALIGELPNGVPQNLLPYVTQTAMGIREKLSVFG
                     DDYDTPDGSCIRDYIYVVDLAKAHVIAMDRILNNKQKEKVEVFNIGTGKGVSVLELINT
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKAEANLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             complement(8964..9860)
                     /locus_tag="ctg15_60"
                     /transl_table=11
                     /translation="MAMTLIVLAATMGNKYGGLKQLEGIGPNGETILDFSIYDAVRVGF
                     DKIVFVISRHFEQEFKKLVSGKYEHVVEVEYVYQDVETIPEEKRNPKRKALYGSVRAVL
                     MGEELIDSPFGVINAVNFYQRESFELLYDNLVMLGEADYHSFNICYRLRNVLAESGGVT
                     RGICEVDEKGYLLSVTDRVGVERISGNPMYPNELHKWVALDDNSLVSMNMWGFTPQVFG
                     EMKKAFDKFIDENGMDMKAHYSIPAFMNERIADGVRVKVIETPARWMGLVSHDDKIQVL
                     LRINDMIRKGIYPSKLF"
     CDS             complement(10001..10603)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_61"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.8e-63, bitscore:
                     205.8, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFITAIFVNNIVLSQFLGICPFLGVSKKVETATGMGAAVA
                     FVLTIATIVTYLIQKFVLDAFGLEYLQTIAFILVIAALVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDFDLLTGVVYAFSTALGFALAMVLFAGIREQLSLVNIP
                     KGMQGMAIALVTAGLLAMAFMGFSGVDKGLGVLFGIE"
     CDS             complement(10622..11206)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_62"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.9e-70, bitscore:
                     228.5, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVLMNGIVKENPTFVLLLGMCPTLGTTSSAINGMGMGLATA
                     FVLICSNVVISAIKNLIPDMVRIPAFVVVIASFVTLLQMIMQAYVPALYATLGLFIPLI
                     VVNCILLGRAEAFAAKNGPVPSFFDGLGMGLGFTLALTILGGVREFLGTGKLFDITIMP
                     EQYGMLIFVLAPGAFIALGYLIAIVNKLKKA"
     CDS             complement(11221..11982)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_63"
                     /sec_met_domain="FMN_bind (E-value: 1.1e-21, bitscore:
                     69.4, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVIVLTAITVIATGLLAYVNQLTAGPIAEANAKALSDAIAVVVPG
                     FDNNPAEAPETIELDGATYKIYKATKGGEFIGAAVESSANGFGGALSVLVGFDKEGNII
                     DYSLLSHAETPGLGSKAADWFKKGAKGDITGMNPGQGALVVNKDGGQIDAITASTITTR
                     AFLKAVNNAYAAYSGQNVDGASGATQQVSETVAENATACDAQCEGNEACKQVCDSTACK
                     TVCSDKCDPANCDKADCKKVECPKQDCKNKK"
     CDS             complement(12009..12998)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_64"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 7.4e-120,
                     bitscore: 391.8, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANKLIVSLSPHVHSGDSIQKNMYGVLIALIPALLVSFYMFGLGA
                     VVVTLTSVAACVFFEWAITKFILKRERSTICDGSAIITGVLLAFNLPSNLPLWIIIIGA
                     LVAIGVGKMTFGGLGCNPFNPALVGRIFLLISFPVQMTSWPLVQQWGSYTDAETGATPL
                     ALMKMAVKGDVNALGQLPDTLSLFLGNNPGSLGEVSALALLLGLGYMLWKKIISWHIPV
                     SILVTVFVFAGLMHLVDPVAYASPLAHLFTGGLMLGAIFMATDYVTSPMTHKGMIIYGV
                     AIGFLTVVIRLFGAYPEGMSFAIFIMNAFTPLINTYCKPKRFGEVVKK"
     CDS             complement(13013..14350)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_65"
                     /sec_met_domain="Fer4_7 (E-value: 7e-09, bitscore: 28.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1.2e-16, bitscore: 52.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 7e-53, bitscore:
                     170.7, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 5.5e-31, bitscore: 98.7,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.4e-05, bitscore: 15.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKTFRIGGVHPAENKLSAGKAIETLALPKQAVFPLSQHIGAPATA
                     IVKKGDVVKVGTKIAEAGGFVSAAIFSSVSGKVNKVDAVIDASGYRKPAIFIDVDGDEW
                     EESIDRSSTLVKECALTPEEIVAKVKNAGVVGMGGACFPTHVKLSPPPGCKAECVIINA
                     VECEPYLTADHRLMLEKADEVLVGVSILMKAAKVTKGYIGIENNKPDAIKLMTEKAAQY
                     PGIEVVPLQVKYPQGGEKQLIDAVIGRQVPAPPAIPINVGAVVQNVGTAFAVYEAVQKN
                     KPLFERIVTVTGKSVRNPSNFLTRMGTPMSQLIDAAGGLPEDTGKVIGGGPMMGKALVN
                     TEVPICKGSSGVLIMNDKEAARAEAQPCIRCAKCVNVCPMGLEPFLLATLSAHKDWERV
                     EKEDVMSCIECGSCQFTCPSHRYLLDYIRLGKGTVGGIIRARNAKK"
     CDS             complement(14390..15244)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 40.5; E-value:
                     1.1e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_66"
                     /sec_met_domain="Fer4_7 (E-value: 1.1e-12, bitscore: 40.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 9.6e-10, bitscore: 30.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 2.3e-08, bitscore: 26.0,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1.5e-08, bitscore: 26.6,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1.2e-07, bitscore: 24.4,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 5.2e-10, bitscore: 31.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.2e-05, bitscore: 15.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="YEDPRIAKVSEVLPQANCGGCGYPGCSGFAGACVKAADAGSLEGK
                     LCPVGGAPVMEKVAALLGLEAVAAEPKVAVVRCNGSCENRPRTALYDGAKSCAIAHATS
                     GGETGCTFGCLGCGDCVEVCQFDAIHMNPETGLPEVDEEKCTACGACSKACPRKIIEIR
                     PKGKNNRRVVVMCVNKDKGAVANKACKASCIGCGKCVKVCPFEAITLENNLAYIDPAKC
                     KSCRKCESECPKGAIQAINFPPRKPKVEVPAGEAAAKPAAKVEASKVETPEAVKADAPK
                     AEA"
ORIGIN
        1 atgtctatgg agaacctgcc aacgccactg tacaggatgt atggagcgga gaaagtttat
       61 ggcaccaata cttggcaaac ctggggtata tcatagtcag catcgagaac cgtggtgcca
      121 atgcaccccg tggacgcgaa tggcgcaaat gtatttatgg agaagtcgga acctttgcca
      181 gtgaagatca ggcaagaggc atccaagact tggcacgtca atactctttc attgacacca
      241 cacgtatcgg tatcaccggc tggagtggtg gaggcagcca gactctgaat agtatgttcc
      301 gttatcccga tgttttccac acaggcattg ccattgcttt tgtagcagac cagcgtctgt
      361 atgacacgat ttatcaagaa cgttacatga acacccctca aaataatccg gagggttacc
      421 gcaaagggtc tcccatctcg tatgcagcag gattgaaagg caacttgctg ttaattcacg
      481 gtacaggaga tgataatgtc cattaccaga attgtgaaat gttggtcaat gaactggtac
      541 ggcacggaaa gatcttctca cagatttctt accctatgcg ttcccatgga atttatgaag
      601 gcgagggaac cagcttgcat ctgcgaaaga caatggctga ttactggttg aaaaacctgc
      661 ctgccggagg aaaataaata tgccaaaact tttgctgata tgattatata gtttgccatt
      721 ctgggcatta gtgaagcttt tcatatacat aaagtgatta gaaaccaaat ctttcacaaa
      781 agttcaggat ggcagactga taaatctgct tcgttttagc aaactttaca ctaaaccaaa
      841 acacataaac taaatgaaga aaatacaact attcttatta ctatttctgt taatatccat
      901 tacgcagcac atcaatgccc aattccctgt caaaacagaa tataccgttg agatgggagg
      961 aacatcgggt aaaggaactt acgcacctat gtggcttact gccaataggc aaggtttatc
     1021 ttctgtcaat actgaaaatg gttatttacg ggcaggaatt gcacacacaa tgccattaaa
     1081 ccaacatttc ggcttcagtg caggactgga tttggcaacc gcctacaatt tcacctcctc
     1141 attcatcatc caacaggcct atgcagacct tagctaccga tggttgaacc tgagcatcgg
     1201 cagtaaagaa cgcttgcccg aattaaagaa ttccaagtta agcagtggag gcatggtaga
     1261 atcaaataat gcccgcccca ttccccaagt acgcttggaa gttccctatt atgtagccat
     1321 accaggtacc cataaatggc tttatttgaa aggacacata gcctatggac gttttactga
     1381 tgacaaatgg caggaacatt tcacttccat aggtaacaaa tatgccattg atgtacttta
     1441 ccacagtaaa tcgcttttcg ccaaagtagg aaacaaagaa cattttccgg tagaatttga
     1501 aggaggaata caaatgtccg ctcaattcgg cggagaccaa tatattgcag gacaaaaaga
     1561 gcctgtaata gatatgccta cccggtttgt tgactttatg tgcgtattgg ttcctatggc
     1621 tggagatgat accacacccg aaggcgaaca agtaaacatc tacggaaacc atgtcggtag
     1681 ttggaatttt gccgcaacag cttatcttaa ccagtggaag gtaaaaatct attatgaaca
     1741 ttatttcgac gatcactccc aaatgttttt ccaatacgga cgctggaaag acggacacat
     1801 cggactggaa ataacttttc caaaaaaccg cttcattgat acttttgtat acgaaggatt
     1861 aggaacaaag gatcaaaccg gacctatgct gtatgattcc ttttgggggg agtttgaaga
     1921 gcaaatcagt gctaaagata attattacaa tcattacctc tatcaaggat ggcagcattg
     1981 gggaatggga ataggcaatc ctctacttcc cggacctatt tacaacaaga atggacagat
     2041 tacttttatc agcaaccgtg tactggcaca tcacatagga ttctgcggtt ccccctgcca
     2101 atcgctgagt tatcgtatgc tactctccta ctcccgtcat tggggtactt atgataatcc
     2161 tctgaatgaa ataaagaaac aattcaactc tttgtttgaa gtaacttatg ctccacaaca
     2221 actgaaagga tggagtttca ctgtatccgg agctatggat cgcggcagca tgcttggaaa
     2281 taattatggt ggaatgctgg ttatccgcaa acaaggaatt atcaaatcag gcaataaata
     2341 aaagttttaa ctgtcaaccc aatcaacata tgaaacaaat attattattc atactcttta
     2401 tgctgggaat cagcagttgt gacaaagctc ccatcaatgg caaattagat ggcagatggc
     2461 aattaatgac tatagaatat actaatggaa aaatagaaga atgtaaccgc atttattata
     2521 gtatccagtt acatttggtg gaaatcagtg ccaaaggtgg aaatggaggc actcatatcg
     2581 gacgtttctc ttataaagga gatgaggtaa ccatgagtga attccgccac cggggagatg
     2641 aagaaaaact aacgacactg aatgaattga aacctttcgg acttaatcaa gctattaatc
     2701 atcttaaagt ggaaaaagca acaggcaaga aactaattct gaaatctgat tatgcacgcc
     2761 tcacattcag aaagttctaa aaaagtatac cacagactac gcaaactatc tgctgataaa
     2821 atatgaaaaa acaatttata cgctatagcg gtgacaaaac actatgccgg atttctagaa
     2881 attaatttat cggcaggaat aaaactagtg ccaccactca tggagccggc tttacaaata
     2941 ttgaagccgg cttcataaaa caagttcttt actttcctgt agtctgtggt gaaataaatt
     3001 tatcttctag gcttaatatc caattttacc ggtttcaaca tgttctccgg acttagaatt
     3061 gtatccaact cttccttatt taaaatacca tgttccaaga ccagttcata gacacttcta
     3121 cctgtttcca acgcttcttt tgcaatcttt gtagaatttt tataaccaat aatcggattc
     3181 aatgcggtta ctacaccaat actgttatgc acttcaatct tgcagcgttc cgcattagca
     3241 gtaatacctt ctacacaacg tgtacgcagg gtttcaaaac cattgaccat taaatctaca
     3301 gattcaaaac aacactgtgc catcaccggt tccatagcat tcagttccat ttgagcagct
     3361 tcgccagcca tagtcacgca tagttcgtta cctattactt tataacaaat ctgattcatc
     3421 acttcaggaa tcaccggatt caccttacct ggcattatag aagatcccgg ttgcatagcc
     3481 ggaaggttga attctcctaa accacaacgc ggtccactgg ccagcaaacg taaatcatta
     3541 catattttat ttacttttac ggctaccctt tttaaagctg aagcataacc taccaagcag
     3601 gaagtatctg aagtagctcc taccaaatct gacgacaatt tgaaatcaaa acctgtaatt
     3661 tcacacaatg cttccacaca tttttctgca tatcccggtt ccgcacaaat gcctgtacca
     3721 atagcggtag cacccatatt tactgtcagg aagtctgccg ccgcttcatt caaatgacga
     3781 atttcgtctc tcaatatact ggcaaaacca ttgaatgtct gacctaaagt cataggtacg
     3841 gcatcttcca actgagtacg ccccattttg atgatatgtg caaactcctc tcctttctta
     3901 tggaatgcac caatcagcga ttccaaataa ggaagaaaac gaagatgaga ataatacata
     3961 ccaatatgga ttgcagtggg ataagcatca ttcgttgatt gtgagcagtt cacatggtca
     4021 ttaggagagc aatattgata ctcgccacgt ttgtgtccca taatctccaa agcacggtta
     4081 gcaatgactt cattagcatt catattggta gaagtaccgg cacctccctg aatcatatcc
     4141 accgggaatt gctcatgatg ctcaccattt aagatttcct gacacgccaa tactatggca
     4201 tctttttgtt ctttagttaa taaacctaac tcatagttag ccattgcagc tgccattttc
     4261 gtaatggcaa gaccgttaat aaacaacgga tattcattta gatgaaattt actaattggg
     4321 aaattttcta tgcctcttag agtttgcaca ccatacaatg cactggccgg aatttcgcgg
     4381 gcaccaatta aatcactttc tactcgggtt tcttctgtaa gttttgtttc catgatcagg
     4441 ttatttatta gtttatcatt tcttatttta tatagcaaag gtataaacta acattttgat
     4501 atcaaaatat aatctgatat aattttaaaa tattatttta tacatgttta ttgctgcaaa
     4561 acagacaaca aacttacatt atgaaagttt actcagttaa caaagtctta tatcctttga
     4621 agttcattca aaaaacagac ataaaaaaag gcgtccattc agaacgccct tattctattt
     4681 tttaacttcg gaactcttat ttcaccttta ttctatcaaa gccttctcca aatacaccaa
     4741 tgacagcact ttgtgataca aatgcgttcg gatcgatatc ttttatcaaa cggaatatag
     4801 tagtagactc acgttttttt gccagcacaa acatcatttt cacacccgca ccggtataac
     4861 aacctactcc gtcaatgaac gtcacccctc gatgaagatc tttatttatg cgatgcccta
     4921 tttcttcatg cttcttcgaa atgataaaga attgcactga ctgacgagca ctatttacca
     4981 cctgatccaa gacaaagctg gatataaaca agacaacata tccatatacc accttctccc
     5041 aatcatgcaa tacaaaataa ctggaagaga taataaccaa atcacacatc aaaataaccc
     5101 ggcccaaagt aatatcacga tacttattga caatagcagc tataatatcc gtacctcctg
     5161 tgctaccatt ggcagaaaaa gcgacaccaa taccacctcc gcagaaaaag gctcccaaga
     5221 cacaagccat gaaaggttga tcatgtatta aagactctcc ccctgtcaaa tcctgtatga
     5281 taggcagaat agaagtcagc acaaatacag catagatggt tttcacacta aacttccatc
     5341 ccaaaataac caaagaaagt atcaacaata ctccgtttat tcccaaatag gtgtactgga
     5401 ccggcaaacc ggtagcccaa taaacaatag aagcaatacc tggcaccgca cctgaaggaa
     5461 ggtcattagg taacaaaaag acggtccatc cgatagcata catcagcata ccaagagcaa
     5521 tcaacatata atcccttagt tctctgataa cccgttgctt acgcgtcgta ataaagactg
     5581 aatccatgtg agttttcctt tataaaatca tattgtccgc aaaagtacaa aaagattgaa
     5641 tcacttggct tcaaaaggtg acattttttc aagtaaaaag tcctgttaat ctgatttatc
     5701 aaaaacaaca gtacttttca ccctttatta ttctttgggg tgtaaatacc aatctttata
     5761 atccgcacca aaagaatctc tccactgttt aaactcggga taataggtgg taatagacac
     5821 cttctctgaa ggccatctaa attcactgtt actgatattt atagcgaaag gcatattatc
     5881 ttctgctata taatacattg gggtaccatt ggaatcttga ctcaaatcac tacccgtacc
     5941 acgtaaactc tcatcagcta cgcttgtcgg cttatagcct gacaaatgta cttcatgaga
     6001 acgtttattc acaaaaatga aagaattgta aggcggataa gcatccatat cgcttacttt
     6061 atcatatttt ttaaatccga tcactacagt cacaggcttt ttgagaacag gctttatatc
     6121 agaaaaaagt attaatacag gcttttctat tcccggctca aagttttttc cgatcacatt
     6181 accttcttga ctcacctgca ccaaatcaat atgctccttc cctacgtaat ccaactggaa
     6241 accaaaccca tttgtataag tagcaccatc attcatcgga gtaaaagtag tagtggtgcg
     6301 caccaatgcg ttagaagatt tatcttttac aactgtactg gaataatata tcacaacatc
     6361 attcatatca taatcattct tatcaggcca attgtcctca taagccaaag accctttgac
     6421 tacatacgaa atttcaccct tatttacttc atccggtata ttaggagtag gttctacaga
     6481 agaagaagca gatgccataa tagcaaactg tacatcatta aaacgcatgt ccacattatc
     6541 ttccatagcc ataaagaaac aattgtccag ttccggatca cttaacaaaa ctgaacgttg
     6601 ctctttatta tcgttatatg caggattaga ataacgagga aaaacaccct tttcttttcc
     6661 aaatcccatt cccaataaaa tccatccaat atgagtgcct tgggggaatt catcttcata
     6721 cttgctttgt tccttattcc aatattttag ttttatttgc tcaccgacta aagatttagg
     6781 agcattccta ctggaacgag gaatcaggat ggtctttttt atggtagcca tgtccacgga
     6841 ctctccttct ttataagtat aataagcaac catatcctcc cacgtagtag acgagaaatt
     6901 aaaataagtc gctaccaaac ctgtagattt agttattacc atatcattac tccctgaagt
     6961 acgcagttcc ggaaatcttt ccaacaaatt acgattatct actactatag aacggcttaa
     7021 attactgcat ctctctaaaa aagcaccagg tatatccaac ttttcaggca acaaataatc
     7081 aggaacccca ttttcattcc aattacccaa tacatcatat ccgtcaggat aactcactcc
     7141 tcccattact gctctagaac gcccatcggc agacagttgt gccttataat caacataatt
     7201 aaaggttagt ccgtcagata gtaattccaa ttcaacaggt gatacgacca acacattatc
     7261 agttaccagc catacctttt tcaaataagc cggcaaagat acttttgaaa aaaatctacc
     7321 attcatatca gtcgaagcag cataaatggg atttatatct ttaaactccc aagtattttc
     7381 aactaattcc ataggatatt catcatacag ataaaaagca gtctgtactt tcataccata
     7441 atcaataata agttgactat tacggacagt agtaaaatca aaaaaatcgt ctttattgat
     7501 tttttcctcc tcttcttccc ctccccccgt gtatatatca tgcatattac gcaagcaaga
     7561 cacaaagaaa actgataagc agatgatcca aaattttgtt ttcataaagt agtgcgtgat
     7621 tattttcgac aaatatagcc ataaataact aaaaaacaac taaatagtca aaaaaaactg
     7681 tcccccgact cacgtcggag aacagccaca acacaaacac aaaataaaac acgacaaaac
     7741 tactatgcaa ttttttagcc tgctctatgt tttgagtaac ataactaccg ccaatcaggt
     7801 attcacatat ccaagagggg tttcaggtta tttgcatcta taaaacgcca cactagcgtc
     7861 ctttgttcat cggtctttct aaaaatatct taattcttat tgaattcctc tttctcttag
     7921 cttcaactgc cagttccaag ccgaacgtag cgtgtcctcc aaattggctt ctgccttcca
     7981 tcccaactcc ttattagcga agtcaggatt agcccatacc ttctcaatat ctccggcacg
     8041 acgacccacg atctgataat taagtttcac accggtagct ttttcaaatg tattgatcag
     8101 ttccaataca gaaacgcctt tacccgttcc aatattaaag acttccacct tctccttctg
     8161 cttgttattc aaaatgcgat ccattgcgat aacgtgagcc ttcgccaaat ccactacata
     8221 tatatagtca cggatgcaag aaccgtccgg tgtatcataa tcatccccaa acacactcag
     8281 tttttcacga atacccattg ctgtctgagt aacgtagggt aacaagtttt gtggaacacc
     8341 attaggtaat tcacctatta atgcagtggg atgtgcgcca ataggattaa agtaacgcaa
     8401 cataatagca ttaataggcg atcccgaagc aactgtatca cgaataattt cttcattgat
     8461 ctgttttgta ttaccatacg gagactcagc cttcttaatc ggagcctctt ccgttacagg
     8521 aagaacatcg ggctgaccat acaccgtaca tgatgatgaa aaaataatac cttctactcc
     8581 atgtttcggc attaactcca acaggttaat caatgaaacc aagttattgc gataatacaa
     8641 caacggtttt tgtaccgatt cacccacagc cttgctagcc gcaaaatgaa taataccttt
     8701 tatgcccgga tatttagtaa acagcttgtc cattccctca aaatccaagc aatccaactt
     8761 ttcaaatgca ggacggattc ctgaaacctt ttctatatta tctaccacat cggcgcttga
     8821 attggacaaa ttgtccacaa tcactacgtc gtaaccgcta ttttgcagct ctactaccgt
     8881 atgagaaccg atgtagccgg ttcctcctgt tactaaaatt ctttctttca taatacttaa
     8941 tattctgtcg ttttctaata ggttcaaaac aacttcgacg ggtaaatccc ttttcgtatc
     9001 atatcattga tacgaagcag gacttgtatc ttgtcatcat gcgataccaa ccccatccat
     9061 ctggcaggtg tctcaatcac tttcaccctg actccgtcag caatacgctc attcataaaa
     9121 gccggaatag aataatgagc tttcatatcc attccattct catctataaa cttatcgaac
     9181 gccttcttca tctcaccaaa tacctgcgga gtaaatcccc acatattcat tgaaaccaag
     9241 ctgttgtcat ccaaagctac ccatttatgt aattcattag gatacatcgg atttccactt
     9301 atccgttcta ctcctacacg gtctgtaacg gacaacagat atcccttttc atccacttca
     9361 caaataccac gggtaacccc tccgctttcc gccaatacat ttctcagcct gtagcaaata
     9421 ttgaaactat ggtagtcagc ttctcccaac atcaccagat tatcatataa caattcaaaa
     9481 ctttctcttt ggtaaaagtt cacggcattt atcacaccga atggagagtc aatcaactct
     9541 tctcccatca aaacagctct taccgagccg tacagtgctt tgcgtttcgg attacgcttt
     9601 tcttcaggaa tcgtttccac atcctgataa acatactcca cttctaccac atgttcatat
     9661 ttgcctgata ccagtttctt gaattcttgt tcaaaatgtc tgcttatgac aaatacgatc
     9721 ttatcaaatc cgactcttac ggcatcatat atggaaaaat ctaatattgt ttcgccatta
     9781 ggacctattc cctccagctg tttcaatcca ccatatttat tccccatagt ggccgcgagt
     9841 acaatcaagg tcatagccat ttaatctctc tattaattct aatgcaaaaa taagcataaa
     9901 aattgaattt acggacaaga acaatggatt tctttctaat aaaaaagtcc gaagctgtgc
     9961 tccggacttc tgaatcggtt tattttaacg atgaagtgaa ctattctatt ccaaacagaa
    10021 cccccaaacc tttgtctaca cctgaaaatc ccatgaatgc cattgccagc agaccggcag
    10081 taaccaatgc gatagccatt ccctgcattc ctttaggtat attcaccaaa cttaattgtt
    10141 cacggatacc tgcaaacaat accatagcca aagcaaaacc aagagctgta gagaaggcgt
    10201 aaaccacgcc agtcaacaaa tcaaaatctt tctgaatgac caagatagct acacccaaaa
    10261 tacagcagtt agtggttatc aacggaagga atactcctaa tgcctgataa agggcaggag
    10321 acactttctt caatatgatt tccaccatct gtaccaatgc tgcaatgaca aggataaacg
    10381 caatggtctg caaatattcc aacccgaaag catcgagtac aaatttctgg ataagatagg
    10441 taacaatggt agcgatggta agcacgaatg caacagccgc acccataccc gtagctgtct
    10501 caactttttt ggatacaccg aggaacgggc agatacccaa gaattgtgac aacacaatgt
    10561 tgttcacaaa tatagcggtg ataaatatca atatatattc catattctta ctttttacgg
    10621 gttatgcttt cttcagttta ttcacaatcg caataaggta tcccaatgca atgaaggctc
    10681 ccggtgcgag aacgaaaatc aacattccgt attgctcagg catgatagtg atatcaaaca
    10741 acttgcctgt gcctaggaac tcacgtaccc caccaaggat agtcaatgca agagtaaatc
    10801 cgagccccat acccagtcca tcgaagaatg aaggcacggg accgttcttt gctgcaaaag
    10861 cttcggcacg tcccagcaga atacagttta ctacgatcaa tgggatgaac aagcccaaag
    10921 tagcataaag tgccggcaca tatgcctgca taatcatctg caacaaggtt acgaatgatg
    10981 caataaccac aacaaaggcc ggaatgcgca ccatatcagg tatcaaattc ttaatggccg
    11041 aaattacaac attagaacag attaatacaa aagccgtagc caatcccatc cccataccat
    11101 tgatggcaga agatgttgtt cctaatgtag gacacatacc caaaaggagt acaaacgtgg
    11161 gattctcttt tacaatcccg ttcatcaata ctttaaaatt attcatagtc tgctccttcc
    11221 ttatttttta tttttacaat cttgcttggg acattctact tttttgcagt ctgccttatc
    11281 gcagttagca ggatcacatt tatcgctaca aacagtcttg caggctgtag agtcacaaac
    11341 ctgcttacat gcctcgtttc cttcacattg agcatcgcag gcagtagcat tttcggcaac
    11401 agtttcagac acttgctgag ttgcaccact agcgccatcc acattctgac cactatatgc
    11461 tgcataagca ttgttcacag cttttagaaa agcacgtgta gtgatggtag aagctgtgat
    11521 agcatctatc tgaccaccat ccttatttac caccaatgct ccctgtcccg gattcatacc
    11581 ggtaatgtcg ccttttgcac ctttcttaaa ccaatcagcc gcctttgacc ccaagcccgg
    11641 agtctcagca tggctcaaca aagaatagtc tatgatattt ccctctttgt caaaacctac
    11701 cagcacactc aaagcgccac caaaaccatt ggcagaagat tctacggcag caccaataaa
    11761 ttcgccaccc ttggttgcct tatatatttt ataagtagca ccatccaatt ctatagtttc
    11821 aggagcttcc gcaggattgt tatcaaaccc cggaactaca actgcaatag cgtcactcaa
    11881 agcttttgca ttagcctcag caataggacc ggcagtcagt tggttgacat aagccaaaag
    11941 tccggttgca atcacagtaa tcgccgtcag tacgataacc atgtttttca aagatgattc
    12001 tagttttttc atttcttcac gacctccccg aatcttttag gtttacaata agtattgatt
    12061 aacggagtga atgcgttcat aatgaatata gcgaaagaca taccttcggg atatgcaccg
    12121 aacaaacgga taaccacggt caggaaaccg atagccacac cgtatataat cataccttta
    12181 tgagtcatag gcgaagtaac atagtcggtt gccatgaaaa tagcacccaa catcaaacca
    12241 cctgtaaaca agtgagccaa cggagatgcg taagccaccg gatcaaccaa atgcatcaga
    12301 ccggcaaata caaatacagt caccagaata gatacaggaa tatgccagga aataatcttt
    12361 ttccatagca tatatcccag gccaagcaat aaagccaatg cactcacctc acctagcgaa
    12421 cccgggttat tacccagaaa cagacttaat gtatcgggca actgacctaa agcatttaca
    12481 tcacccttta cagccatttt catcaatgcc agcggagtag caccggtttc agcatcggta
    12541 taacttcccc attgttgaac caacggccat gaagtcatct gcacaggaaa agaaatcagc
    12601 aagaagatac gacctaccaa cgcaggatta aaaggattac aacccaatcc gccgaaagtc
    12661 atcttgccca caccgattgc caccaacgca ccgatgataa taatccaaag cggcaagttg
    12721 gaaggcagat tgaatgccag caacacaccg gttataatag ccgaaccatc acagatggta
    12781 gagcgttctc tcttcaaaat aaacttggta atcgcccatt cgaagaatac acaagcagca
    12841 accgaggtca aggtcaccac cacggcgccc agtccgaaca tataaaatga caccagcaac
    12901 gcaggtatca acgcaatgag tacaccatac atattcttct gtatgctgtc accgctatga
    12961 acgtgaggcg ataatgatac tattaattta ttagccatac tattttgtcg aattattttt
    13021 tagcattacg tgcacggata ataccgccta ctgtgccctt acccaaacgg atatagtcca
    13081 gcaaataacg atgagacgga catgtaaact gacacgaacc gcactcgatg cacgacatta
    13141 catcttcttt ctctactctc tcccaatcct tatgagctga aagtgttgcc aataagaaag
    13201 gctccagtcc catgggacac acgttaacac acttggcaca gcggatacag ggctgagctt
    13261 ccgcacgggc agcttcctta tcattcataa tcagcacacc cgaactacct ttacaaatag
    13321 gaacttctgt attaaccagt gctttaccca tcatcggacc accaccaatc acttttcccg
    13381 tatcttcggg caaaccgcca gccgcatcaa tcagctggct catcggagtc cccatacggg
    13441 tgagaaaatt agatggattt ctgacagact tacctgtaac ggttacaatg cgttcaaaca
    13501 aaggtttgtt tttctgaacg gcctcataaa cggcaaatgc agtacctaca ttctgaacta
    13561 ccgcacccac attgatagga atagcgggag gagcaggaac ctggcgaccg atcacagcat
    13621 ctatcaattg tttctcacca ccttgcggat atttcacctg caagggaacc acctctatac
    13681 cgggatattg agcagctttt tcagtcatca acttaatagc atccggttta ttattttcaa
    13741 taccgatata tcccttggtc acttttgcag ctttcatcag gatgcttaca cccaccagta
    13801 cttcgtctgc cttttccaac atcaaacgat ggtcggcagt gaggtaaggc tcacactcta
    13861 cagcattgat aattacacat tccgccttgc agcccggagg aggagaaagt ttcacatgag
    13921 taggaaaaca agcaccgccc atacctacta cacctgcatt tttcacttta gcaacgattt
    13981 cttcgggtgt gagagcacac tctttcacca atgtcgaact gcggtctatt gattcttccc
    14041 attcgtcacc atccacatcg ataaagatag ccggcttgcg gtaaccgctt gcatcgatta
    14101 cggcgtctac cttgttcact ttaccggata cagacgagaa gatggctgct gaaacaaagc
    14161 cacccgcctc agcaatcttc gtacctacct tcaccacatc gccttttttc acgatggcag
    14221 tagcaggagc accgatatgc tgtgacaaag gaaataccgc ttgcttagga agtgcaaggg
    14281 tttcaatggc tttgcctgct gacaatttat tttctgctgg atgtactcca ccaattctaa
    14341 atgtcttcac tgttatatct ttttaatttt tacttacttt gaattttgat tatgcttccg
    14401 ctttcggagc gtcagctttc accgcttccg gagtttccac ctttgaagcc tctacttttg
    14461 cagcaggttt tgcagcagcc tcaccagccg gcacttctac cttcggttta cgtggcggga
    14521 aattaatagc ttggatagcc cctttcggac attccgattc acatttacgg caagatttac
    14581 acttagccgg atcaatgtat gccaaattat tctctaacgt aatggcttcg aatggacaca
    14641 ctttcacaca ctttccacaa ccaatacaac tagccttgca agccttgttg gcaacagctc
    14701 ccttatcctt gttcacacac atcaccacta cgcggcggtt gttctttcct ttcggacgga
    14761 tttcaataat cttgcgcgga caagctttgc tacaagcccc acaagctgta catttttctt
    14821 cgtccacttc cggaaggccg gtttcaggat tcatgtgaat agcatcaaac tgacacactt
    14881 ccacacaatc accacaaccc agacaaccga atgtacaacc cgtctcacca cctgaagtgg
    14941 catgagcgat ggcacacgat ttagctccgt catacagagc agtacgaggg cgattttcac
    15001 aactaccgtt acatcttacc accgcaactt tcggttcggc agcaacggct tccaatccca
    15061 aaagggcagc tactttctcc attaccggag caccaccaac cggacataac ttaccctcca
    15121 gcgaaccagc atcggcagcc ttcacgcagg caccagcaaa accagagcaa ccgggataac
    15181 cacatccacc gcaattcgcc tgaggaagca cttcgctcac cttggcaatc cgcggatctt
    15241 catac
//
