LOCUS       gnlProkkaCDCLAIEN_75    9627 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CDCLAIEN_75.
ACCESSION   gnlProkkaCDCLAIEN_75
VERSION     gnlProkkaCDCLAIEN_75
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 02:44:51
            Original ID  :: gnl|Prokka|CDCLAIEN_75
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9627
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9627
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5608:6396]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5609..6396
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..9627
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9627
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             439..828
                     /locus_tag="ctg75_1"
                     /transl_table=11
                     /translation="MTKKVYTKPELKSEAFVPQTHVAACGDSGTVYKFTCDAPRGTLYY
                     FRDKPASGSQPTTGNRGIWLGNYHPCSAFHEAEAQSGFYWGYVDYNHNQKFEKSELVIV
                     WRGQKGWEGHATKNLDINSWETAKS"
     CDS             1169..1564
                     /locus_tag="ctg75_2"
                     /transl_table=11
                     /translation="MKKDYQKPMLISEEFIPNEYVAACYNFKALFHCHYGENNTNNHGK
                     PCATTYVDINGIHATGHEGTIEKWGIPILNIDWNGFDLSDAKVGDEIGGIKWTSYDTVN
                     NTGEYNHQGWGEIKSAVEEIPGRPNHS"
     CDS             2020..3123
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_3"
                     /sec_met_domain="PF04055 (E-value: 5.4e-31, bitscore: 97.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESLQDINPVERALVNKATANRTPINATIELTPTCNFRCDMCYIR
                     MEKSQAEKRGGLRSIEEWLHIADQLQEIGTLFILLTGGEPLLYPDFKELYIRLKEKGFI
                     LTINTNATLIDDETVRLFQRLKPRRVNVSLYGVTNGTYLNLCHATNGFDRCLEGLKRLK
                     EYGIDTKLNLTLTRQNIKEHRQMLELADEWDLPMLTNSYISVYSRPGCATTLPLDTCRP
                     VPDEVAHAEVEALEHKYGKEYTSYATHVLQQLERGESPVPAEGIGLACRAGKSSAWINW
                     QGVMTPCVDMETPAVSLLSTTVSDAWKQIVTKCEQLPFHKECAGCTLRSICDVCYANAR
                     NEKGQCGGIGYLCRIAKSKKKQMKGSL"
     CDS             3159..4265
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_4"
                     /sec_met_domain="PF04055 (E-value: 7.4e-25, bitscore: 77.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHLHDANLLERALVDKANQSRVPITTNFELTPTCTLNCDMCFIR
                     TERSVVERHGGLSPLQQWLDWAEQLQDMGTLFILLTGGEPMLYPHFKELYTRLREMGFI
                     LTLNTNGTLIDNEMVRILQTHKPRRINVTLYGDSRETYGRLCHNPQGYTLCMEALKRLK
                     KADIDVKLNVSIVRKNEKDYDEIIRLAQHLDIPAEVNSYMFPLSRPECGSLRNILTERL
                     DADEAARIEMQYMEYKKGNDMARYMHDLKYTLAHVEGTRACSLECRAAKSSCWINWQGI
                     LTPCVMLDQPAVDLKKIPMTTAWQQLLEEAKELVSHTECEGCHLRPVCNVCYAAAHCEK
                     TITGSMDYLCQMAKAKERIITNYPPVIH"
     CDS             4278..5153
                     /locus_tag="ctg75_5"
                     /transl_table=11
                     /translation="MRLNIGPLTIELSGVTEQEIPVNSRLFLDHKPATKEADRYYTFYF
                     VNRLPLPSNDWQITFQRNDIVVFRKEEQETRLLAVGNLNACYALYQERNERDANIYFIE
                     GLKRELQTDTLFISCLCLERPLSVQGCYILHCTFLDYRGQAILFSGPSGIGKSTHANLW
                     CRHIPGTQVLNGDRALLCPLPNGDYEITGWPVCGSSGICHNERRPLEAIVFIEQASDNT
                     IRPQTAMKHFKALCSQVTINWWNPKLTGKALDDLQVLTRQTSISTYACNMNPEAAFTLH
                     RYLTKLEIIR"
     CDS             5172..5612
                     /locus_tag="ctg75_6"
                     /transl_table=11
                     /translation="MKTVDTKEYISMLRTLIEEGKQVSMIISGSSMAPFLIHARDHIYL
                     KSPSGELRKGDMVFYQRSNGEYVMHRIYNVKNEEYYLIGDAQTVIEGPIQREQIFAIII
                     KVKRKGKWIVPEDFQWKFFAHIWPNIIPLRRTIIKTYRFFKR"
     CDS             5609..5890
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_7"
                     /sec_met_domain="PF05402 (E-value: 1.3e-17, bitscore: 53.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 4.8e-15,
                     bitscore: 45.1, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRTKEFIKRNIAGEIVLVPSGQTAREFNGMVTLTETGEFIWEHI
                     EEAESFNHLVLLILEEYEVDKDTASQDAAGFIMQLLQAGMIRPTGINW"
     CDS             6127..6396
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_8"
                     /sec_met_domain="PF05402 (E-value: 4.3e-18, bitscore: 55.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2e-10,
                     bitscore: 30.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLNSNLILRQVGGEYMIVNPFSETMDMAQVYSLNETAAWLWKQL
                     ENKEFTVDEAGALLCNEYEVNKDTARNDANELCRQWLETGLAIE"
     CDS             6406..7488
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_9"
                     /sec_met_domain="NTP_transf_5 (E-value: 4e-35, bitscore:
                     111.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISAPLQKAFMLLLRQGLWDRQEDCSALFPLDEKEWNEIHSMARK
                     QTVQGIIYDGIRLLPTEAVPPRKVLLGWMVEVDTLERVNRQHRETIKALQQIYVQSPSI
                     PFLLLKGIGTADFYPHPEHRIAGDIDLWFGNKTQTEQANQRMEKLGLPVKRGTNGEASC
                     LINRVLIEHHSRLIELHNPFLQKEIRQWEAGVFTNSQGKLPSEANHLLLSTHILKHLIN
                     EGIGLRQLCDIAMAFNALHSVTNKNELECICRKWHIHRWNRLLYALLIKYLGVPADLLP
                     FSTSLCPDKLMQEIWESGNFGHGDERYGERPTGKWANKRYTLKRIFHKMHLSLGYAFDE
                     TFWWLAGLALLRFKEMIKKK"
     CDS             7485..9173
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 222.1; E-value:
                     2.2e-67)"
                     /gene_kind="transport"
                     /locus_tag="ctg75_10"
                     /transl_table=11
                     /translation="MKELLKKFLQKLTRENLSNTCQLGWKAFKWVMQVTEGYHWLITFS
                     IFSGIFGVVMSLVNVAMSKWIIDVATGTQEGNIYLVATIVALSFLLGMGIKLVSPWIFG
                     KINMRISIRMQNSLSDALMMCSWKGAGKWHTGDLLTRISSDASEVLGMGMGILPNLLVT
                     GLQLASSFIYLWILDARLAWFILGVTPLVLLSKIYFRKVRELSCAQKKMNSEMGTVMQE
                     NLSKRILVRSLGATNYRKQKLHETQEKLFKLGMEQIKFSTFTQGVMGFTFGGGYLCAFL
                     WGIFQLHNHEITFGTMTAFLQLVGQVQGPFFGLISIPPSLIRGWTSVERLMALFEDVEP
                     DEHPVYIDQPLTLNFRKVSFGYEEGQPVLDRFTAAFHPGSSTAIAGPTGTGKTTIIRLI
                     LALVYPEKGRIDLTTDDGRTLSVTPDLRINFVYVPQGNTLLSGTIRENLWLGSPGADEE
                     ALHKVIRLACAEFVFSLPEGLDTKIGEHGYGLSEGQAQRIAIARALLRPGRIWLFDEAS
                     SALDTETTTHLIDNLLQWGKNNTLIFVTHDSRLMERCDQVIHIKE"
     CDS             9195..9626
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_11"
                     /sec_met_domain="Poly_export (E-value: 5.7e-14, bitscore:
                     41.6, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKTIKLACLLAIIIFSSCASRKDFVYLQDMDELQEYPMVQKYEA
                     IIHRDDRLSIIVNSKNPELSLPFNMSGSRSYSVEADGSISNNEVGVLSDEKEKGYLVDI
                     NGNIDFPVLGQLHVEGLTRRQLTELIKKRLINEELLKDPM"
ORIGIN
        1 gtattctcat cctcccccac ctacgtcaac ggagtatcgg aagccctgtt caactgtgga
       61 ctctgtctgc cttcgggatc aatgatgacg tgcgaggatg tgatgcgtgt agcggatgcg
      121 atacggagta tgagatagat aatttattta ataacagaca gagttctgca agaacttggc
      181 tatatgaaag tttcatagta aagagaaaat tgtaagatgt taggaatttg gagatggaac
      241 gtgaacaagc cgaaagcgac atgtcacatc cggatattta tctccgtaaa tcggtaaaga
      301 ctgtaaatca cagtcgtttc atccttttta ttcttgattc ttattgattg agttcttgca
      361 gaactcggtc atgtttttcc cttttcaaac ttttgccctc ttacagaata agaagtctgg
      421 caaaacaaga aaaaaaagat gacaaagaaa gtttatacaa agccggagct gaaaagcgag
      481 gctttcgtgc cgcaaacgca tgtggctgct tgtggagata gtggaactgt ttataagttt
      541 acttgtgatg caccaagagg aacgttgtat tattttagag ataagcctgc ttctggttca
      601 caacccacta caggaaatcg aggtatttgg ctaggaaact atcatccatg tagtgcattt
      661 catgaagccg aagcccaatc tggtttttat tggggatatg ttgattacaa ccataatcag
      721 aaatttgaga aaagtgaatt agtcattgtt tggagaggac aaaagggctg ggagggtcac
      781 gccaccaaga accttgacat aaattcttgg gaaactgcta aatcctaatc ggtaaataaa
      841 acagtaaatc gcaatcttat tcatttattt caatcttgat tcctaacgct tagataaatt
      901 tattgattct cattaataga aatagagatt aaataatata tgatcagact actggaggaa
      961 ctaagtcaga atatcgtttg agctgcaaag aattagtgta atgaaaagga aaatgaaagg
     1021 atcatattgt agatggtaaa tcgcaatata tcaattattt caaaattctt tcacaccgga
     1081 gtttctccgg gacccaatca ctatttcgct tcaaaccttt tctgatttcc tttcctccga
     1141 aacaggaatc aaaaaagaaa aaaatagtat gaagaaagat tatcaaaaac cgatgcttat
     1201 tagcgaagag ttcattccga acgaatatgt agctgcatgc tataacttta aagcactatt
     1261 tcattgtcat tatggagaaa acaatacaaa caatcatgga aaaccatgcg ctacaaccta
     1321 tgtagatatt aatggtatcc atgctacagg gcacgaaggg actatagaaa aatggggtat
     1381 acctattctc aatattgatt ggaatggatt cgatttaagt gacgcaaaag taggtgacga
     1441 gattggaggc atcaagtgga ctagctatga tacagtaaat aacactggag aatacaatca
     1501 tcaaggttgg ggtgaaatca aatctgctgt tgaagaaata ccaggtcgtc ctaaccactc
     1561 ttaagacatt cccctattta tgaaattcgc atcaaataac agtatagact tggaccttaa
     1621 aagtaaagtc tatactgtaa acctctcaaa ttagggttct aaaatatcta tcttcgctgc
     1681 gaatcaaaat ttacgaatta tgcaaagcaa tgaagacctt gaaagattct actttcccta
     1741 tctttgggtc tatcatcgta aaatatagac ttggttgtat gccaatagtt aaaaatcaat
     1801 cgaatttgat aatatctttt tgtgagatgc caattctggt gccttataaa aaggatatgc
     1861 tctaaattaa gtattaactt ttgttgggct tcaaaaaggg aagataatct atatattttc
     1921 catcgagaca aatttcggta acatatacga ccacggaagt aaatgaaatc caatacacta
     1981 gactcaaaaa cttttctttg aaaaaaaatc attatcctag tggaatccct gcaagacata
     2041 aaccctgtgg aacgggcatt ggtgaacaaa gcgacggcaa accgtactcc gatcaatgcc
     2101 actattgaat tgacaccgac gtgcaatttc cgttgtgata tgtgctatat ccgcatggag
     2161 aagtcacaag ccgagaaaag aggaggatta cggagcatag aggaatggct gcacattgcc
     2221 gaccagctac aggaaatagg aacgctcttc atcttactga caggaggcga gcccctactc
     2281 tatcctgatt tcaaagaatt atatatccgg ctgaaagaaa aaggattcat cctcaccatc
     2341 aatacaaacg cgactttgat agatgacgaa acagtacgtc tgtttcaacg tttgaaaccc
     2401 cggagggtga atgtctcgtt atatggtgtg accaacggaa cttatctcaa tctgtgccac
     2461 gcgacaaacg gtttcgaccg ttgcctggaa ggactgaaac gattaaaaga atatggcata
     2521 gataccaaac tgaacctcac cttgacacga caaaatataa aagaacaccg gcaaatgctg
     2581 gaactagctg acgaatggga cttacctatg ctgaccaaca gttacatttc agtctattca
     2641 cggccgggat gcgccaccac gctacccctt gatacgtgcc gccccgtacc ggatgaagtg
     2701 gcacatgccg aggttgaggc actggaacat aaatatggca aggaatacac atcatacgcc
     2761 actcatgtcc tccagcaatt ggaacgtgga gaatctcccg tacctgctga aggcatcgga
     2821 cttgcctgcc gggcaggtaa aagttccgca tggatcaact ggcagggcgt catgactccg
     2881 tgcgtcgata tggaaacacc agccgtttcg ctactttcca caaccgtaag cgatgcctgg
     2941 aaacaaatag taaccaaatg cgaacaactt ccgttccata aagaatgcgc aggttgtacc
     3001 ttacgctcta tctgtgatgt ctgctatgcc aatgcccgca atgaaaaagg gcaatgcggc
     3061 ggcatcggct acctttgccg cattgcaaaa agtaaaaaga aacaaatgaa aggaagtcta
     3121 taaagacttt tctcataaat acatatacat tccaagttat ggatcatctt cacgatgcca
     3181 accttttgga acgggcattg gtggacaaag ccaatcagag ccgtgtcccg atcactacca
     3241 acttcgagct gactcccacc tgtacgctca actgcgacat gtgcttcata cgcaccgaac
     3301 gcagcgtggt ggaacggcac ggaggtttat cgcctttgca acaatggctc gactgggcag
     3361 aacaacttca agacatgggt acactcttca tccttctcac cggaggtgaa ccgatgctct
     3421 atccacactt caaggagctg tacacccggc tgcgcgaaat gggattcatc ctgactctca
     3481 atacgaacgg cacactcatc gacaacgaaa tggtacgcat cttgcagacc cacaagccgc
     3541 ggcggataaa cgtcaccctg tatggagaca gcagagaaac ttacggacgc ttgtgccaca
     3601 atccgcaagg atacaccctg tgcatggaag ccctgaaacg gttgaaaaag gcagacattg
     3661 atgtgaaact gaacgtaagt atcgtacgaa agaatgaaaa agattacgac gagatcatcc
     3721 gtctggccca gcatctggac attccggcag aagtaaactc atacatgttt cctctctcac
     3781 gccccgaatg cggaagtctg cgtaacattc taactgaaag actggatgcc gacgaggcgg
     3841 cccgcatcga gatgcaatat atggagtaca aaaaagggaa tgacatggca cgatacatgc
     3901 acgacttgaa atatacgctt gcccatgtgg aaggaacacg agcctgctct ttggagtgca
     3961 gagctgccaa gagttcatgc tggatcaact ggcaaggcat cctcaccccc tgtgtgatgc
     4021 tggatcaacc ggccgttgac ctgaaaaaga ttccgatgac aactgcatgg caacaacttt
     4081 tagaagaagc caaggaactg gtatcccata ccgaatgcga gggttgccac cttcgtcccg
     4141 tatgcaacgt atgctatgcc gccgcacact gtgaaaaaac aatcaccgga agcatggact
     4201 atctttgcca gatggcgaaa gccaaagaac ggatcattac gaattatccc cccgtaatac
     4261 attaaaaact gaagattgtg agactgaata tcggcccgct aacgattgaa ttgtcaggag
     4321 tgacagaaca ggagattcct gttaacagcc gtttgtttct cgaccataaa cccgctacca
     4381 aagaagcgga ccggtactat acattctatt ttgtcaaccg tctgcctttg ccgtccaacg
     4441 actggcagat cacattccaa cgcaacgaca tcgtagtttt ccggaaggaa gaacaagaaa
     4501 cacgcctgct ggctgtagga aacctgaatg cctgctatgc tctctatcag gaaagaaacg
     4561 aaagagatgc caacatctat ttcatcgaag gtctgaaaag agaactgcaa acagataccc
     4621 tgttcatttc ctgcctgtgc ctggaacgtc ctttatctgt ccagggatgt tacatactac
     4681 attgtacttt tctggattat cgtgggcaag ccatcttatt cagtggtcct agcggcattg
     4741 gcaaatcgac gcatgccaac ctgtggtgcc ggcatattcc cggcacccag gtactcaatg
     4801 gcgaccgtgc cctgctctgt ccccttccaa acggcgacta cgagataacg ggatggcctg
     4861 tatgcggttc cagcggtatc tgtcacaatg aacgccgccc gttggaggcc attgtattca
     4921 tcgaacaggc atctgataac accatccgtc cccagacagc catgaagcat ttcaaagctc
     4981 tctgctcgca ggttacaatc aactggtgga atccaaagct caccggcaaa gcactcgacg
     5041 atctgcaggt tttgaccaga cagacaagca tcagcaccta tgcgtgcaac atgaatccgg
     5101 aagcagcctt caccctgcac aggtatctga ccaaactgga aattatccga taatgtgaaa
     5161 tacgccccat tatgaagact gtcgatacga aagaatatat atccatgctg cgtaccctca
     5221 ttgaggaagg aaagcaggtg agcatgatca tctcgggcag cagcatggct ccattcctga
     5281 tccacgcaag agaccacatc tacctgaaaa gcccctccgg tgaacttcgg aaaggagata
     5341 tggtgttcta tcagcgaagc aacggtgaat atgtcatgca ccgtatttat aatgttaaaa
     5401 atgaagaata ttatcttatc ggtgacgccc agactgtcat cgaaggtcca attcaaagag
     5461 aacagatttt cgccatcatt atcaaggtga agcgaaaagg gaaatggata gttccagaag
     5521 atttccagtg gaaattcttc gcccacatat ggccgaacat aattccttta cgcaggacca
     5581 tcattaaaac atatcgtttt ttcaaaagat gaaaagaacc aaagaattta tcaaacgaaa
     5641 catagccgga gaaatcgtac tggttccttc cggacagacc gcccgagagt tcaacggaat
     5701 ggtcaccctg accgaaaccg gagaatttat ctgggagcat atcgaagaag cagaaagctt
     5761 caaccatcta gtactgttga ttctggagga atacgaagtg gataaagaca ccgcatcgca
     5821 agatgccgca ggatttatca tgcaactgct gcaagccggc atgatccgtc ccacaggtat
     5881 aaactggtaa acagtaatct gttcaattca gatatgacaa acaatacaat aagaaatgtt
     5941 agaagagaga ttcgttttct tcgcgagaag cgccggatct gtaaaaaatg ttagatcagg
     6001 taagttcaag accctatgtt atcagcggat aatagaatga acttacattt tattccccat
     6061 tacatctgcc tgtgaaggtc gatgtaattt taactataaa taggataatg caataatata
     6121 aagacaatga gactcaattc taatttaatt cttcgccaag taggtggaga atatatgatt
     6181 gtcaatccgt tttctgaaac catggatatg gcacaggtct attccttgaa tgaaacagcc
     6241 gcctggctat ggaaacaatt ggaaaacaag gaattcacgg tagatgaagc cggagcactg
     6301 ctgtgcaatg aatatgaagt aaataaagat acagcccgaa acgatgccaa cgagctgtgc
     6361 cgacaatggt tagaaactgg gttagccata gaataagaca aaaagatgat ctcagcccca
     6421 ttacaaaagg ctttcatgct tttgctaagg caaggactgt gggaccggca ggaagactgt
     6481 tccgcccttt ttcctctaga tgaaaaggaa tggaatgaaa ttcacagcat ggcaagaaaa
     6541 caaaccgtac aaggcattat ttacgatggc atccgcctgt tgccgactga agccgtacct
     6601 ccccggaagg tattgcttgg ctggatggtg gaagttgaca ccttggaacg ggtgaaccgg
     6661 caacaccggg aaacgattaa agccctccaa cagatttatg tacaatcacc ttctatccct
     6721 ttcctgctgc taaaagggat agggacagct gacttctacc ctcatccgga acatcgcata
     6781 gccggagaca tcgacctgtg gttcggaaac aagacacaaa ccgaacaagc caaccaacgg
     6841 atggaaaaat taggattacc ggtaaaaaga ggaaccaatg gtgaggcttc ctgtctgata
     6901 aacagagttc tgattgaaca tcacagcagg ctgatagagt tgcacaaccc tttcctccaa
     6961 aaagaaatcc gccaatggga agcgggggtc tttaccaaca gccaaggcaa acttccgagc
     7021 gaagcgaatc atctattact ttccacccac atattgaagc atcttatcaa tgaagggatc
     7081 ggactacgac aattgtgtga tatagccatg gcttttaacg cattacattc tgttacaaac
     7141 aaaaacgaat tagagtgtat ctgtcgcaaa tggcacattc accggtggaa ccggttactt
     7201 tatgccctat tgataaaata tcttggcgtg ccggccgacc ttttaccatt cagtaccagt
     7261 ctctgtccgg acaagttaat gcaagagatt tgggaaagtg gcaattttgg acatggagac
     7321 gaacgttacg gtgaacgtcc caccgggaaa tgggcgaaca aacgatacac gttgaagcgg
     7381 atctttcaca aaatgcactt atcgttaggt tatgctttcg acgaaacttt ctggtggctg
     7441 gccggattag ccctcttacg tttcaaggaa atgataaaaa agaaatgaaa gaattgctga
     7501 aaaaattttt gcagaagctc acacgggaga atctgagcaa tacatgtcag ttaggatgga
     7561 aagctttcaa atgggttatg caggtaacag aaggatacca ttggctcatc accttctcta
     7621 tcttttcggg tattttcgga gtggtcatgt cattggtcaa tgtggccatg tccaaatgga
     7681 tcatcgatgt agctaccgga acacaggaag ggaatattta cctggtagcc acaatagtag
     7741 ccttatcctt cctgctgggt atggggataa aacttgtatc tccctggatt tttggcaaga
     7801 tcaacatgcg catcagtatc cgcatgcaaa attcgctgtc cgacgcccta atgatgtgtt
     7861 catggaaagg agcagggaaa tggcacacag gcgacctgct gacccgtatc agcagtgacg
     7921 cttccgaagt gttgggaatg ggaatgggca ttctacccaa cctgctggtt accggcttgc
     7981 aattggcaag ctcttttatc tacttgtgga ttcttgacgc gcgtttagct tggttcatac
     8041 tgggagtcac ccctcttgtt ttattgtcaa agatttattt cagaaaggtc cgggaactga
     8101 gctgtgccca aaaaaagatg aacagcgaga tgggtaccgt catgcaagaa aatctgtcca
     8161 aacggattct agtccgctcg ctcggagcca ccaactaccg gaaacagaaa ttacatgaaa
     8221 cacaagagaa gttgttcaaa ttgggaatgg aacaaatcaa attttccact tttacgcaag
     8281 gggtcatggg atttacattt ggaggagggt acttatgtgc attcctttgg ggtattttcc
     8341 aactgcataa ccacgagata acattcggaa caatgacagc ctttcttcaa ctggtcggac
     8401 aggtacaggg accttttttt gggttaatat ccatccctcc cagtctgata cggggatgga
     8461 cctccgtgga acggttaatg gccctctttg aagatgtaga accggacgaa cacccggtct
     8521 acatagacca accactgaca ctgaactttc ggaaagtgtc ttttggctat gaagagggac
     8581 agccggtact cgaccggttt acagctgcct ttcatccggg aagttccacc gccatagccg
     8641 gacctaccgg aacaggaaaa acgaccatta tccggctgat actggctttg gtttatccgg
     8701 aaaagggacg catcgatttg acaactgatg acggacggac actcagtgtg acccccgatt
     8761 tacgcatcaa cttcgtctat gtgccccaag gaaatacgtt gctgagcggt accatccggg
     8821 agaatttatg gctgggtagt ccgggagcag acgaagaggc tctgcataaa gtcatccggc
     8881 tggcctgcgc tgaatttgtg ttcagtctgc cggaaggact agataccaag ataggggaac
     8941 atggatatgg cttgtctgaa ggacaagccc aacggattgc aatagcccgc gcactgttgc
     9001 gtcccgggcg gatctggctg tttgatgaag catcatcggc acttgacacc gagaccacca
     9061 cacacctcat agacaatttg ttgcaatggg gaaagaataa cacattaata tttgtgacac
     9121 acgattcacg actgatggaa cgatgtgacc aagtgattca tataaaggaa taaaaaacaa
     9181 ttaattataa aacaatggat aaaacaatca aactggcctg tctgttggca ataatcattt
     9241 ttagttcgtg cgcttcacgc aaagattttg tctatttaca agatatggat gaactacagg
     9301 aatatcctat ggttcaaaaa tatgaagcca tcatccatag ggatgacaga ttgagtatta
     9361 ttgtgaacag caaaaaccca gaactgtccc tgcctttcaa tatgtccgga agcagaagct
     9421 attctgtaga agcagacgga agcatttcca acaatgaagt gggggtatta agtgatgaaa
     9481 aagaaaaagg ttatttagtg gatatcaacg ggaatataga ctttcctgtg ctgggacaac
     9541 tgcatgtgga aggactgacc cgccgacaat taaccgaact gatcaagaaa cgactgatca
     9601 acgaagaatt gctgaaagat cctatgg
//
