LOCUS       c00210_gnlPro..        14477 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CDCLAIEN_210.
ACCESSION   c00210_gnlPro..
VERSION     c00210_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:44:41
            Original ID  :: gnl|Prokka|CDCLAIEN_210
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 22068
            Orig. end    :: 36545
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14477
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[32068:36544]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14476
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..14477
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14477
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(1763..1912)
                     /locus_tag="ctg210_23"
                     /transl_table=11
                     /translation="MFIENPYQWGVSYDYALPLSENTLLHIHSHGAIHTYKLMRMYVKR
                     FSPE"
     CDS             complement(2065..2508)
                     /locus_tag="ctg210_24"
                     /transl_table=11
                     /translation="MSYIQNNLQAGEEIKYKADIHWYIFAYPVILLLLSVFFSSAQTGF
                     FHYVSLFLLLSGLFQLIKRILLKMGTEYVVTNKKVILKSGILSRDALELVLNKCEGIRI
                     NQSLMGRMLGFGSIVVTTGGVTNKFDFITNPIKFRNEINAQIQ"
     CDS             complement(2667..2975)
                     /locus_tag="ctg210_25"
                     /transl_table=11
                     /translation="MSTPQFYNIGKGKRIEIKVCNEDSIQIRRVRCLLYYSNSGKKECI
                     GKIWISPLIGYETCYFCMNVDIPLTKDEWHKLTFRIKRGKNYKDYKFLKQQVQEENI"
     CDS             3644..4207
                     /locus_tag="ctg210_26"
                     /transl_table=11
                     /translation="MTNIIDNMLSLCPVSEDTIQELKKCMILCRFPKKYQLIKENTFCK
                     SAYFIEKGMTRSFWLVNGEEITTSFSWEGGIVFSMDELYYNKPSEEFVETLEDVVVYKI
                     SLVDLTKLFQTNIELANWGRIIHQNEYRRLHRSHKERLTLPAKERYEEFKQQFPQICQR
                     VKLRYIASYLGITLPTLSRLRAKK"
     CDS             4325..5476
                     /locus_tag="ctg210_27"
                     /transl_table=11
                     /translation="MEKISSAAFTDTKPHYDLLDGLRGVAALMVIWYHVFEGFAFASAG
                     NIETLNHGYLAVDFFFILSGFVIGYAYDDRWGKNFTMKDFFKRRLIRLHPMVIMGAVLG
                     AITFCIQGCVQWDGTHVAISMIMLSLLCTIFFIPAMPGVGYEVRGNGEMFPLNGPCWSL
                     FFEYIGNILYALFIRRLSNKALAVLVVLLGMALASFAVFNVSGYGNMGVGWTLDGVNFL
                     GGTLRMLFPFSLGMLMSRNFKPMKVNGAFWICTIILIALFSVPYLEGLEPICMNGIYEA
                     FCVIAVFPFLVWLGASGTTTDKQSTKICKFLGDISYPVYVVHYPLMYLFYAWLIENKLY
                     TLGETWYVAVGVFVLSVILACLCLKLYDEPVRKWLSKKFLAPK"
     CDS             complement(5650..6075)
                     /locus_tag="ctg210_28"
                     /transl_table=11
                     /translation="MNETIYLKKLEQREIKPTAIRLLILKTMMQHKEAFSLLDLENELD
                     TVDKSTIYRTITLFLAHHLVHGIDDGTGSLKYAVCSNDCNCEVDDLHTHFYCENCHRTF
                     CMKSIHVPIVTLPPGFTVQSINYVLKGLCSECSHQHV"
     CDS             complement(6098..7807)
                     /locus_tag="ctg210_29"
                     /transl_table=11
                     /translation="MKKIKLESVFNEFTLMGIAVSGAFYLGEYWEGIAVILFYLIGEWF
                     QHKAVHKARSNIKALLDVRPETATVVYNNTYKITAPEKVQPGETIEVKVGEKVPLDGFL
                     LEDSASFNTAALTGESVPRTLYKQEEVLAGMIASDKVVRIKVNKPYDQSTLARILTLVQ
                     DAAERKAPAELFIRRFARIYTPIVTGLAILVVILPYLYSLIKPEFIFVFDDWFYRALVF
                     LVISCPCALVVSIPLGYFGGIGAASHKGILFKGGNYLDAITQINTVVFDKTGTLTQGVF
                     SVQAISAAEGVSQKELLQLIASIESFSNHPIAKAIVKYAEEQSISLNSSLRITEFAGYG
                     IKAVTNGKEVYVGNTRLLSKYGISFPYEISNMTETIVLCAMENKYLGYLSLADTPKPDA
                     VQAIRELKDLNINNIQILSGDKQTIVSNLAEKIGVTHAFGDLLPEGKVAHLEQLKANFE
                     NRVAFVGDGINDTPVLALSDVGIAMGGLGCDAAIETADVVIQTDQPSKVAEAIKIGKQT
                     HRIVWQNISMAFGVKLLVLLLGAGGMATMWEAIFADVGVALLAIFNAMRIQK"
     CDS             7905..8723
                     /locus_tag="ctg210_30"
                     /transl_table=11
                     /translation="MKKKYWAFLIGSWCLSVGMQAAKVDTLSVHSDAMNKEVQVITICP
                     DKAMAGEKCPVLYLLHGYGGNAGTWLGIKPELPQIADKEGIIFVCPDGKNSWYWDSPLN
                     KEYRYETFVSKELVNYIDKNFTTKVERGGRAITGLSMGGHGSLWLSIRHKDVFGGGGSM
                     SGGLDIRPFPNNWEMKKQLGEEASNKQRWDEHTVINQLDKIKNGDLAVIIDCGCDDFFL
                     EVNKAVHEKLLKKKINHDFIIRPGGHTGRYWNNAIDYQILFFSKFFNKSK"
     CDS             8728..9486
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg210_31"
                     /sec_met_domain="adh_short (E-value: 2.9e-56, bitscore:
                     181.3, seeds: 44, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKIVFITGASSGIGAGCARKFASQGASLILNARNVNKLSALKEE
                     LEKQYGTEIYLLPFDVRDRKAATSALESLPKEWQSIDILVNNAGLVIGTDKEQEGSLDE
                     WDIVIDTNVKALLAMTRLIVPGMVERKRGHIINIGSIAGDAAYPGGSVYCATKAAVKAL
                     SDGLRIDLVDTPLRVTNIKPGLVETNFSVIRFRGDKEKADNVYKGIRPLTGDDIAETVY
                     FAASVPEYMQIAEMLVMPTYQATGTIVSRK"
     CDS             complement(9578..9826)
                     /locus_tag="ctg210_32"
                     /transl_table=11
                     /translation="MEKKTVKYHIPQHGIYMYARTNSGKTELIVLNSTNAEQVVANNHY
                     RIMTNDSKSGKELISGKKIDLTKNMTVGARQSLIIEL"
     CDS             complement(10001..11161)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg210_33"
                     /sec_met_domain="OAD_beta (E-value: 5.5e-153, bitscore:
                     500.2, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEFINFLGNNLADFWTYTGFANATVGHIVMILIGLFFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALAMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKHERLIRMKPPRVVSHTEKVMFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDTITILLGLTVGAS
                     TQASEFLTIDSILIFALGALSFIIATASGVIFVKIFNLVLGKDNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(11163..11594)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 64.7; E-value:
                     1.8e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg210_34"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.1e-20, bitscore:
                     64.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNIYKVAIGDIEDNIAHVEVNGTPYKVEMEKAPKAV
                     VKPVVRPASTSPAPAPTTVVKPAATSTGKSGVKSPLPGVILDIKVNVGDTVKKGQTIII
                     LEAMKMENNINADKDGKITAINVSKGESVLEGTDLVIIE"
     CDS             complement(11618..12547)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg210_35"
                     /sec_met_domain="OAD_gamma (E-value: 4.2e-15, bitscore:
                     47.5, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLNIGIFLSLLLMVGLCSCGEQKSNTKLVLNEVLIENESNFQD
                     DYGVHSAWIEIFNRSFGSADLAGCLLKVSSQPGDTATYFIPKGDVLTLIKPRQHALFWA
                     DGEPNRGTFHTNFTLNAATNNWIGLYDSGKKLLDQIIVPAGTLQANQSYARVSDAANEW
                     EVKGSSADKYVTPSTNNKTINSNAKMEKFEEHDSVGIGMSISAMSVVFVGLLLLFIAFK
                     VIGRISVNLSKRNAMKVKGITDKQEAKEKKLGEAPGEVFAAIAMAMHEMQSDVHDVEET
                     VLTITRVKRSYSPWSSKIYTLRETPHKK"
     CDS             complement(12575..14128)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg210_36"
                     /sec_met_domain="CT_Btheta (E-value: 1.6e-291, bitscore:
                     958.2, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRATARMGGGDKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYIFAQDFTVSAGSLS
                     ETMSLKICKVMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAKTEEEGLAMIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNEIIPDSPN
                     KPYDMYEVISAIVDNGEFLEVQPHYAKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPLVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKEQENPAAFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRIIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             complement(14231..14476)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg210_37"
                     /sec_met_domain="Glyoxalase_4 (E-value: 4.7e-11, bitscore:
                     34.3, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LEPTSPESTIAKFIEKNNGNGGMHHLAFAVEDGVANALAEAETTG
                     IRLIDKAPRKGAEGLQIAFLHPKSTLGVLTELCEKP"
ORIGIN
        1 atctgtttgt cttccaatga tggtttggtg gcgttcgtct gaattgaaaa atgggctttg
       61 gcacggataa aatcaatttc tgccaaaaac tcgtatgact ggaggatggc ggggacctgt
      121 ggacggacta tgatagagaa atctgtcagg atacggatga tttcccggcg ttcttctcct
      181 tccaattccc gtattctatt gtttgcttcc actacttcgg ccggttctat gaaaactgtt
      241 ttgccagtgg atgattcatc gtgtacaatt cccttgattt tccgttttaa tcccggtgcg
      301 acagggatga cgagtcttcc gtcacgcatg gtaggagtta catctttatc aacataacct
      361 tctgcttgag cgttgcgtag aattgcattc aaactgcgtg atatgcttcc ggctgtcgag
      421 gccaactctc tgcggatgcg taataattcg gaagaagcgt tgtctttgat ttttccgaat
      481 ttgtctaaga tgttgttaat acgcgtaatg agttgaggaa acacgataat atctcctgcc
      541 agtttttgta gggcagggta gggggagttt tctttttctt gttcttcgtc attcggggtc
      601 agtgtcagaa aatggatgat atcacgaatt gtttctaaag aacggcgtaa atcaaacagt
      661 tcttgctcat ccaaatacat accttctacg cggatacgtt ttagtgatgg gcgtacatca
      721 aaaaaatatt ggtcgggaaa actgtcttcc tcttgtatga tgcgtatgaa ttccatcacc
      781 tgttccagcc attcattaat atccttaaag gattctgaga agttcatttc atctactctt
      841 tcttgaccta atgtgctgag acatttctct tttagtaaat gacggatgga atcgaaacct
      901 attttctgtt cgaaattctg agggtatatc atgatttatt tctttcgttt attattcgta
      961 tgcaaaaata cgatttgaaa attttatagc aaaaaaactg gtaaactatt tgcttattta
     1021 aaataaagtc gtacctttgc aacgctttca acggaaagca cttctgaaaa gaagtcttgg
     1081 agaggtggca gagtggtcga ttgcggcggt cttgaaaacc gttgtactgc gaggtacccg
     1141 gggttcgaat ccctgtctct ccgcaataag tattgaaaat caatgagtta taataaaaac
     1201 acccaatctt acatatagaa agattgggtg tttttattat tttatctaag tatatccaga
     1261 ctcacctgca acggacttta gcttttataa agatcatttt gttctctgat caatttcgga
     1321 aagtgtcctt gacgtattat ctttctcact agaaagttcg ggggtattta tgccctcatg
     1381 ccctcactgc atgtataata ggttaattat aaatgactta tatgacaata gtaaaaatat
     1441 ttgctttcac ttatactctc atgccctcac tatgttttga ggttgatttt tacataatat
     1501 gcttgctgtc agctatatat tctcttttta tagaccgttc cagcttggta taaagtagag
     1561 cgttttcaag cttttttctc gtaagaatgc gcatgaaggg gggagacact tccacggaat
     1621 gatagcttac gaattcccgg cagcgataaa aaaagagcaa gacattttaa aaaaaactct
     1681 tgttctttaa aaaaaaggcg gttatctttc ttgaaaagct cttgatcttt ttaaaaaacg
     1741 tccttgtctt tgatatggaa tttcattctg gactaaagcg ttttacatac atacgcataa
     1801 gcttgtacgt atgtatagcc ccgtgtgaat gtatgtgcaa aagcgtgttt tctgacaagg
     1861 gtaaagcata gtcatacgac actccccatt gataaggatt ctcaataaac atattaaaac
     1921 attcttttgg tattcctgat tacctttaat acaatactta aacctaagtg cagattatat
     1981 tattctaaca gaggagttcc attacagttt tgtgtataaa agcttttata tccgccccct
     2041 ttgtattctt taaatgcttt tcatttattg aatctgcgca ttgatttcgt ttctgaactt
     2101 tataggattg gtgataaagt caaatttgtt ggtgacccca cctgtagtaa ctacaataga
     2161 accaaaaccg agcatacgtc ccatgaggct ttgattaatc cgtatccctt cgcatttgtt
     2221 taaaaccaat tcaagggcat cccggcttaa aataccggat tttagaatga ctttcttgtt
     2281 tgtgacaaca tattcagtgc ccatcttaag aagaattctt tttatcaatt ggaataatcc
     2341 ggacaataat agaaataagc taacataatg gaaaaatccg gtttgtgcag aagaaaagaa
     2401 aacgcttaat aatagtagta ttaccggata tgcaaatata taccagtgaa tatctgcttt
     2461 gtattttatt tcttcaccag cttgtagatt gttttggata tagctcattg tttttgtaaa
     2521 ttaatagatt gcatagtttt attatcaaaa gacaaatata aggataatca gaatggtata
     2581 aaataaatct tggtttattt taaagctgaa acttaaaata aaaacaattc ttcctgtttt
     2641 tcttcttgtc aatatctctt ttcttatcaa atattttctt cttgtacttg ttgtttcaag
     2701 aatttgtaat ccttataatt ttttcctctc tttattcgga aagttagttt atgccattcg
     2761 tcttttgtta gggggatatc cacgttcata caaaaatagc aggtttcgta gccaatgaga
     2821 ggggaaatcc atatttttcc tatacattct ttcttgccgg agttggaata atataaaaga
     2881 cagcgtactc ttcttatttg tatgctgtct tcattgcata cttttatctc tatacgttta
     2941 ccttttccga tgttgtagaa ttggggagta gacattttta ttttgtttaa aatactatct
     3001 ttatcattta cacagactac ggtgaacttc tctatattgt ttggtgattg ggagaaagtg
     3061 ctttttgtgg taaacaacaa tattaaaagt aatgttataa tttttttcat gtgattggac
     3121 ttgttggtta aagcagtagc agattattaa ttaagatttt actcttctga taatagatac
     3181 ttcatactgc aaagtaaata ttttttttgt tttaagggtt ataattgtta aaatgcaaaa
     3241 atagcctgca tctgccaatc tgtcaagggc tgtttttcat aaaaaatgtt caattctttg
     3301 gtatttcttt tggattttct tggtatgaaa tttctgatag attatatgaa aagtgatttg
     3361 aaggctattg caattctttt agagtggtgc attaagcaat gggaagtttt aaaagcttga
     3421 ttggcatttg aatgctttat ctttgtaatt tgaacaaaaa gtaataaata aaagaggtat
     3481 atggacattc ttgtatgggg tggtcttgga aattccgatt atttggaaaa aatgatgtcg
     3541 ttttccaata tatatttgta cttttggctg aaaagaaaac aaggtatatc ccgtgtttat
     3601 atttggtgtt tttttatatg tattttaaat ggactgaggt tttatgacaa acattataga
     3661 taatatgctc tctttgtgtc cggtttctga agatacgata caagaactga aaaaatgtat
     3721 gattttatgt cgtttcccta agaaatatca gttaataaag gagaatacat tttgtaaatc
     3781 agcttatttc atagaaaaag gaatgacgcg ttctttctgg cttgtaaatg gagaagaaat
     3841 aacaacctcc ttttcatggg aaggaggtat tgttttcagt atggacgagt tgtactataa
     3901 taagccgagc gaggaatttg tggaaacgct tgaagatgta gttgtttaca aaatatcatt
     3961 agttgattta accaagctgt ttcagactaa tattgaattg gctaattggg ggaggattat
     4021 tcatcaaaat gagtacaggc gtttgcatcg ttctcacaaa gaacggctga ctttgcctgc
     4081 aaaagaaaga tatgaggagt ttaaacaaca gtttcctcaa atatgccaac gggtgaagtt
     4141 aaggtatatt gcatcttatt tgggtataac acttcccaca cttagtcgtc ttcgagctaa
     4201 aaaataattt atgtattact gtttttttgt cataggacaa atttaaaagc ctttaagttg
     4261 tgtaactttg cagcattatt agtaacggtt aaaaagaatt aattattaaa tctattaatt
     4321 tattatggaa aaaatctctt ctgcagcatt tacagataca aagcctcatt atgatcttct
     4381 tgatggattg agaggagtcg ctgctcttat ggtaatatgg tatcatgtat ttgaaggctt
     4441 tgcttttgct agtgccggta atatcgagac tctcaaccac gggtatcttg ctgtggattt
     4501 cttttttatt ctttcgggtt ttgttatcgg ttatgcgtat gatgaccgtt gggggaagaa
     4561 tttcactatg aaagactttt tcaaacgccg tttgatccgt cttcatccga tggtaattat
     4621 gggtgctgtt ttgggagcta ttacgttctg tattcaaggt tgcgtgcaat gggatggaac
     4681 gcatgtcgcc atttccatga ttatgttgtc tttgctttgt acaatattct ttattcctgc
     4741 catgccgggt gtgggatatg aagttcgtgg taatggtgag atgtttccat tgaacggacc
     4801 ttgctggtcc ctgttttttg agtatatagg taatattctt tatgcgttgt tcattcgtcg
     4861 tttgtctaat aaagcattgg ctgtgctggt tgtgttgctg ggtatggcat tagcgtcatt
     4921 tgctgttttc aatgtgtctg gttatgggaa tatgggagtg ggatggacac tcgacggagt
     4981 gaatttctta ggtggaacct tacgtatgct tttcccattc tcgttgggta tgttgatgtc
     5041 gcgtaacttt aagcctatga aggtgaatgg ggcattttgg atatgtacta ttatactgat
     5101 tgcgctgttc tcggttcctt atctggaagg attggaaccg atttgcatga atggtattta
     5161 tgaagctttt tgtgtaattg cggtttttcc ttttcttgtg tggctggggg cgtcgggtac
     5221 tactacggat aagcagtcta caaagatatg caagttcttg ggagatatat cctatccggt
     5281 ttatgtagta cattatccgt tgatgtattt gttctacgca tggttgattg agaataaact
     5341 ttatacattg ggagaaactt ggtatgtagc tgtgggtgtt tttgttttga gtgtcatttt
     5401 ggcttgcctg tgtctgaaac tgtatgatga gcccgtaaga aaatggctga gtaagaagtt
     5461 tcttgctccc aaataaaaat actgcatttc ttgatggatg ttcattaaaa ggtcggacac
     5521 tatacaagaa gatattacag ctttgaataa ctgacaatta gatgaatggc atccgatctg
     5581 taaattcgga tgcctgcatt cgattatttc aaaatgggct ttaggattga tttccttttt
     5641 tggcaatagt cacacatgtt gatgagagca ttccgagcat agacctttca ggacataatt
     5701 gatactttgt acggtgaatc cgggaggtag tgtcacgatg ggcacgtgga tacttttcat
     5761 acaaaacgtg cgatgacagt tctcacaata aaagtgagtg tggagatcgt ctacctcaca
     5821 attgcaatca ttactgcaca cggcatattt taacgatcct gtgccgtcat caatgccatg
     5881 aaccaaatga tgggctaaaa aaagggttat ggtgcggtag atggttgatt tgtctaccgt
     5941 atccaattcg ttttccaaat ccaacagtga aaatgcttct ttgtgctgca tcatggtttt
     6001 tagaataagc agacgtatgg ctgtcggttt gatttcccgc tgttccaatt tttttaaata
     6061 gattgtttca ttcataggtc aaatcatttt attcttttca tttctgtatt ctcattgcat
     6121 taaaaatggc gagtaaagct acgcctacat ctgcaaatat agcttcccac atagtggcca
     6181 ttccgccggc tcctaatagc aatactaaca atttcactcc gaatgccatc gatatatttt
     6241 gccatacaat gcgatgggtc tgttttccta tttttatagc ttccgctact ttactgggtt
     6301 ggtctgtttg tatcactaca tccgcagtct ctatagcagc gtcacagcct agaccaccca
     6361 tggcaatccc aacatcgctg agtgccagta cgggagtatc attgataccg tctcctacaa
     6421 aagctacacg attttcaaaa tttgctttta attgttctaa atgtgctact ttaccttcgg
     6481 gtagtaaatc gccgaaagca tgtgtgacac ctatcttttc ggctaaatta gaaacaattg
     6541 tctgtttatc tcccgataat atttgaatat tattaatatt taagtctttc agctcgcgga
     6601 tggcttgtac agcatcaggt tttggggtat ccgccaatga aagatatccc aaatatttgt
     6661 tttccattgc acatagcacg attgtttctg tcatgttgct gatttcatag ggaaaagaga
     6721 tgccgtattt tgataataac cgtgtatttc ctacatatac ttctttaccg tttgttacgg
     6781 cttttattcc atatccggca aattcagtga ttctcagtga cgagttaaga gatatacttt
     6841 gttcttccgc atatttgaca atggcttttg cgataggatg attgctgaaa ctctctatag
     6901 aggcgataag ttgaagcagt tccttttgcg aaacaccttc ggctgccgat attgcctgaa
     6961 cactgaatac accttgggtg agtgttccgg ttttatcgaa tactacggtg tttatttggg
     7021 ttatggcatc tagataatta ccccctttga aaagaatccc tttgtgagat gcggcaccaa
     7081 tacctccaaa gtatcctaat ggaatgctga ccactaatgc gcaaggacat gatatgacta
     7141 ggaatactaa agcccgatag aaccaatcat caaaaacaaa aatgaattca ggttttatca
     7201 gagagtataa ataggggagt atgacaacta gtatcgccag tcctgtcact atcggtgtat
     7261 aaattcgtgc aaaacggcgg ataaataatt cggcaggggc ttttctttct gctgcatctt
     7321 gtactaaagt gaggatacgt gctaacgtac tttgatcata cggtttgttt actttgatcc
     7381 gtaccacttt atctgaagcg atcattcctg ctaaaacttc ttcttgttta tatagagtcc
     7441 ggggaacact ttctccggtt agggcggccg tattaaatga agcggaatct tccagtaaaa
     7501 atccgtctag aggtactttt tctccaactt ttacttcaat ggtttctcct ggctgtactt
     7561 tttccggtgc tgttatttta tatgtgttat tatatactac agtggctgtt tcgggacgta
     7621 catccaataa tgctttgatg ttgctgcgtg ctttgtgtac agctttgtgt tggaaccatt
     7681 cacctatgag atagaacaga ataacggcaa taccttccca gtattctcct agatagaatg
     7741 ctcctgatac agctatcccc attaaagtga attcattgaa aactgattct aattttattt
     7801 ttttcattgt ttctttttat ttatggcaac aaagatagtg gaaagaagat gcaactaaat
     7861 tgcaaattat attgtacttt tacatcgggt aattttttat atacatgaaa aaaaaatatt
     7921 gggctttttt gataggaagc tggtgtttgt ctgtgggaat gcaggcggcc aaagtggata
     7981 ctttgtcggt acatagtgac gcaatgaata aggaggttca ggtaattacc atctgtccgg
     8041 ataaagccat ggcaggtgaa aaatgtcccg tactttatct gcttcacgga tatggaggca
     8101 atgcgggaac gtggctcggt ataaaaccgg aattacctca aatagctgac aaggaaggaa
     8161 tcatttttgt ttgtccggac gggaagaaca gttggtattg ggacagccct ttgaataagg
     8221 agtaccgtta tgaaacattc gtatcaaaag aattggtgaa ctatattgat aagaatttta
     8281 ctacgaaagt ggagagaggg ggacgtgcta tcaccgggtt aagtatgggt ggtcatggaa
     8341 gtttatggtt gtccatccgt cataaagatg tctttggagg aggaggtagt atgagcggag
     8401 gtttagatat ccgtccgttt cccaataatt gggagatgaa gaagcaatta ggcgaagaag
     8461 cgagcaacaa gcagagatgg gacgaacata cggtaattaa tcagttggat aagataaaaa
     8521 atggtgatct ggctgttata atagattgcg gttgtgatga tttctttctg gaagtgaata
     8581 aggctgtaca cgaaaaactg ttgaagaaga aaataaatca tgactttatc atccgtccgg
     8641 gcgggcatac aggcaggtat tggaataatg ccatagacta tcaaatacta tttttcagta
     8701 agttctttaa taaatcgaaa taataaaatg gataaaattg tttttattac aggagcttcc
     8761 agcggtatcg gtgccggatg cgctcgcaag tttgcttcac agggagcaag tttgatttta
     8821 aatgctcgta acgtaaataa actgagtgca ttgaaagaag aattagaaaa gcaatatggt
     8881 acggaaatat atttgcttcc ttttgacgtg cgcgaccgta aggcggcaac gtctgctttg
     8941 gaatcattac ccaaggaatg gcaatccatt gatatactgg tgaataatgc tgggttggtt
     9001 atcggtacgg ataaagaaca ggaaggtagt ctggatgagt gggatattgt catagatact
     9061 aatgttaagg ctttgctggc aatgacacgc ctgattgtac cgggaatggt ggaacgtaaa
     9121 cgaggacata ttattaatat tggttctatt gccggagatg ctgcttatcc gggaggtagt
     9181 gtgtattgtg ctacaaaggc cgctgtgaaa gctttatcgg atggactgcg tatagattta
     9241 gttgatactc cattgagagt gactaatatt aaaccggggt tggtagaaac aaatttttca
     9301 gttattcgtt tccgaggaga taaggaaaag gcggataatg tatataaagg tattcgtcca
     9361 ttgacgggag atgatattgc ggaaactgtt tattttgctg cttctgtacc agaatatatg
     9421 cagattgcag aaatgttggt tatgcctact tatcaagcta cagggacaat tgtttcacgc
     9481 aaataaaaga ggtagaagag atataaataa aggcgaccct ttataaagcc acctttattc
     9541 ttaccttctc attttacctt cttaccttaa aaaacaatta taattcaata atcaatgatt
     9601 gacgtgcacc gactgtcata tttttggtaa ggtcaatttt tttgccactg ataagttctt
     9661 taccgctttt tgagtcattt gtcattatgc ggtagtggtt attagccacc acttgttcgg
     9721 cattggtgct gtttaggaca atgagttcag ttttcccaga attagtacgt gcgtacatat
     9781 atattccgtg ttggggaata tggtacttaa ctgttttctt ttccatcttc gtttaattta
     9841 gtttggtttt acggcgacaa atttatatgt ttttcagcat atcttatata actaatcatt
     9901 caaaattcat aataaatcat tcatttctta atctatatca ataaaaaatc ctcttccaca
     9961 tattagttga agaggatttt atttgttgtt gttcaatgaa ttacatcaag aatccaagta
    10021 aaataccggc tgctacggca gaaccgatta caccagctac gttgggaccc atagcatgca
    10081 tcaacaagta gttggtagga tcatattcca gaccaataac ctgagagata cgtgccgagt
    10141 cgggaacagc agatacaccg gcattaccga taagcgggtt gattttgtta tccttaccta
    10201 ataccaagtt gaatatcttc acgaagataa ctccagaagc agtagcaatg atgaatgaca
    10261 atgcacccag cgcgaaaatc aagatcgaat caatggtaag gaactctgaa gcttgcgtgg
    10321 aagcacctac tgtcaatcct aataagatgg taatggtatc aatcagcgga ccgcgggcag
    10381 tttctgctaa gcgacgggtt acaccgcttt ctttcaataa gttaccaaag aaaagcatac
    10441 ccaatagagg cagacccgac ggaaccagaa aacaagtaag taacaaacca atgataggga
    10501 acattacttt ttctgtatga gaaacgacgc gtggtggttt catacggatc aaacgttcgt
    10561 gcttggtagt gagcagacgc atgataggcg gctggataac cggtaccaat gccatgtatg
    10621 aataggctga taccgcaata gctcccatca ggttaggcgc cagtttggat gaaaggaaga
    10681 ttgctgtcgg accgtccgca ccaccgatga tgccgatagc accagcctgc atcggatcaa
    10741 agcccattgc caatgcaatc atgtatgcac cgaaaatacc aaactgtgcg gcagcaccaa
    10801 tcaacatcag tttaggattt gaaatcaatg ccgagaaatc cgtcattgca ccgataccta
    10861 aaaagataag tggtggatac catccggagg taactccttg atataaaata ttaagaacag
    10921 aaccttcctc atagatgccg actttcagtc cggcttccat gttgaaagga atattaccga
    10981 tcaagatacc aaaaccgata ggaatgagca acatcggctc aaattccttg gccacggcaa
    11041 ggtatatgaa gaataaacct atcaggatca ttacgatatg accaacagta gcattggcaa
    11101 aacccgtata tgtccaaaag tcagctaggt tattccctaa aaagttgata aattctccca
    11161 tattattcaa taattacaag gtcagtacct tcgagaacgg attctccttt acttacattg
    11221 attgcggtga tcttgccgtc tttgtctgcg ttgatgttat tctccatctt catagcttca
    11281 aggataatga tggtttgccc cttttttacg gtatcaccaa catttacctt aatatcaagg
    11341 attacacctg gcaacggaga tttaacgccc gattttcctg tagaagttgc agcaggcttt
    11401 actactgtag ttggagccgg agcagggctg gttgatgcag gacgaactac cggtttcact
    11461 acagctttcg gggctttttc catttctact ttgtaaggag tgccgtttac ttcaacatga
    11521 gcgatattat cttctatatc tccaatggca accttatata tgttaccgtt aatcttatat
    11581 ttatattctt tcatcgtttt atctttttat tggtgactta ctttttgtgg ggagtttcac
    11641 gcaaggtata aatcttagaa ctccacggtg aatagctacg ttttacacga gtaatggtaa
    11701 gaacagtttc ttctacatcg tgtacatcgc tttgcatttc gtgcatagcc atggcaattg
    11761 cggcgaatac ttcgcctgga gcttcaccca gtttcttttc tttggcttct tgtttgtcgg
    11821 taataccttt taccttcatg gcattgcgct tgctcaggtt gacagaaata cggcctataa
    11881 ctttgaaagc aataaacaga aggagcaagc ctacgaatac gacactcata gctgatatgg
    11941 acataccaat acccacactg tcatgttctt caaacttttc catcttagcg ttgctgttga
    12001 tagtcttgtt gttagtgcta ggagttacat acttgtctgc actagaacct tttacttccc
    12061 attcatttgc agcgtcgctg acacgtgcgt atgattggtt tgcctgtaat gtacctgcag
    12121 gaactataat ctgatccaat aatttcttgc ctgaatcata caagccgatc caattgttcg
    12181 ttgcggcatt cagggtgaag ttggtgtgga aagtaccacg gttaggttca ccatctgccc
    12241 agaacaaagc gtgctggcga ggtttgatca aagtcaatac atcaccttta gggataaaat
    12301 aagtagcagt atctccaggc tggctgctca ccttcagtaa acaaccggca aggtctgcgc
    12361 taccaaatga tctattgaat atttcaatcc atgcgctgtg tactccgtag tcatcttgga
    12421 aattgctttc attttcaatc agcacttcat tcagtaccag cttggtgttt gatttctgtt
    12481 ctccacaaga acataaaccc accatcagca gcaaagaaag gaatattcct atatttaatt
    12541 tcttcatgtt caattctcaa tttttaattt ttaattaaag aggaatatta ccatgcttct
    12601 tagccggatt ggttaatttc ttagtttgca actgttgcaa tgcacggatg atgcggaaac
    12661 gggtattacg cggttcaatc acatcatcaa tatagccata tttggcagca ttgtaaggat
    12721 tggcgaacag cttggtgtat tcagcttctt tttcggctag gaatgcggca ggattttcct
    12781 gttctttggc ttcgcgggcg tataatactt ctactgcacc tgcaccaccc ataacggcga
    12841 tttcggcagt aggccatgca taattcatat caccgcgaag ttgtttacag ctcattacaa
    12901 tgtgagatcc gccgtatgat ttacgcaggg taattgttac tttgggtaca gtcgcttcgc
    12961 cgtaagcata cagcaacttg gcgccgtgga ggattacgcc gttgtattct tgtcctgtgc
    13021 ctggaaggaa tcccggaaca tctaccaatg aaacaagagg tatattgaaa gcgtcgcaga
    13081 aacgtacaaa acgcgcacct ttacgtgacg cattgctgtc aagtacaccc gccaggtatt
    13141 ttggctggtt tgcaacaata cctacagatt gtccgttgaa acgtgcgaaa ccaatgatga
    13201 tatttttagc gtagtgaggt tggacttcca aaaactcacc attatctacg atggcgctga
    13261 tcacctcata catatcgtat ggtttgttgg ggctgtcggg gataatttcg ttcaaagagt
    13321 cttccagacg gtcgatagga tcggtacagt ctacataggg agcttcttcc agattatttt
    13381 gaggaatata gcttaacaat ttgcggatca tggctaaccc ttcttcttcc gtcttggcag
    13441 taaaatgagt aacaccggat ttggtagaat gaacgcttgc accacctaag ttttcttggc
    13501 ttacatcttc acctgtaaca gtctttacca ctttcggtcc ggtaaggaac atgtatgatg
    13561 tgccttccat catcaatgtg aagtctgtca gcgcaggaga gtaaacagct ccgcctgcac
    13621 aaggaccgaa aatacctgaa atctgtggaa taacacctga agcaagaata ttgcgttgga
    13681 aaatttcagc ataaccggcc agcgcattga taccttcttg aatacgtgcg ccacccgagt
    13741 cattgatacc gatacaggga gcacccattt tcatggcttg atccattact ttgcagattt
    13801 tcagagacat tgtttctgac agagaaccgg cagaaacagt gaaatcctgt gcaaagatgt
    13861 aaactaaacg tccttctatg gtaccacaac ctgttactac accgtcgccc ggataatgtt
    13921 ttttctccat gccaaaattg gtgcatctgt gttccacaaa catatccatt tcttcgaaac
    13981 tgccttcatc cagcaacatg gctatgcgtt cgcgggctgt atattttcct ttttcatgct
    14041 gttttgcaat tgctttatca cctccaccca tgcgtgctgt agcccggcgt tcgataagct
    14101 cttttatttt ttcaagttga ttgctcattt tacttatgat tttacaattt acgattaaaa
    14161 aatatttcta tttacgcttg aaccagacta aatacactga tttcaatcgt gaatagtcag
    14221 atctcgtgtt ttatggtttt tcgcaaagct cagtcaggac gcccaaagtt gatttgggat
    14281 gtaaaaaagc aatttgcaaa ccttcagcac ctttacgcgg agctttgtca atgagacgga
    14341 tgccagtggt ttccgcttcg gctaacgcat ttgccacacc atcttccact gcaaaagcca
    14401 aatgatgcat accaccgttg ccattatttt tttcaatgaa ctttgcgata gtgctttcgg
    14461 ggcttgtagg ttcgagc
//
