GCA_008662205.1 - 5 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaFHMHNFEJ_25 (original name was: gnl|Prokka|FHMHNFEJ_25)

Region	Type	From	To	Most similar known cluster		Similarity
Region 25.1	RRE-containing	13,404	33,667

gnlProkkaFHMHNFEJ_65 (original name was: gnl|Prokka|FHMHNFEJ_65)

Region	Type	From	To	Most similar known cluster		Similarity
Region 65.1	HR-T2PKS	1	32,032

gnlProkkaFHMHNFEJ_66 (original name was: gnl|Prokka|FHMHNFEJ_66)

Region	Type	From	To	Most similar known cluster		Similarity
Region 66.1	cyclic-lactone-autoinducer	1	10,004

gnlProkkaFHMHNFEJ_67 (original name was: gnl|Prokka|FHMHNFEJ_67)

Region	Type	From	To	Most similar known cluster		Similarity
Region 67.1	ranthipeptide	8,240	25,407

gnlProkkaFHMHNFEJ_73 (original name was: gnl|Prokka|FHMHNFEJ_73)

Region	Type	From	To	Most similar known cluster		Similarity
Region 73.1	NRPS	1	42,186	leucomycin	Polyketide	3%

Region	Type	From	To	Most similar known cluster	Similarity
Region 25.1	RRE-containing	13,404	33,667
Region 65.1	HR-T2PKS	1	32,032
Region 66.1	cyclic-lactone-autoinducer	1	10,004
Region 67.1	ranthipeptide	8,240	25,407
Region 73.1	NRPS	1	42,186	leucomycin	Polyketide	3%

No secondary metabolite regions were found in these records:: gnlProkkaFHMHNFEJ_1 (original name was: gnl|Prokka|FHMHNFEJ_1); gnlProkkaFHMHNFEJ_2 (original name was: gnl|Prokka|FHMHNFEJ_2); gnlProkkaFHMHNFEJ_3 (original name was: gnl|Prokka|FHMHNFEJ_3); gnlProkkaFHMHNFEJ_4 (original name was: gnl|Prokka|FHMHNFEJ_4); gnlProkkaFHMHNFEJ_5 (original name was: gnl|Prokka|FHMHNFEJ_5); gnlProkkaFHMHNFEJ_6 (original name was: gnl|Prokka|FHMHNFEJ_6); gnlProkkaFHMHNFEJ_7 (original name was: gnl|Prokka|FHMHNFEJ_7); gnlProkkaFHMHNFEJ_8 (original name was: gnl|Prokka|FHMHNFEJ_8); gnlProkkaFHMHNFEJ_9 (original name was: gnl|Prokka|FHMHNFEJ_9); gnlProkkaFHMHNFEJ_10 (original name was: gnl|Prokka|FHMHNFEJ_10); gnlProkkaFHMHNFEJ_11 (original name was: gnl|Prokka|FHMHNFEJ_11); gnlProkkaFHMHNFEJ_12 (original name was: gnl|Prokka|FHMHNFEJ_12); gnlProkkaFHMHNFEJ_13 (original name was: gnl|Prokka|FHMHNFEJ_13); gnlProkkaFHMHNFEJ_14 (original name was: gnl|Prokka|FHMHNFEJ_14); gnlProkkaFHMHNFEJ_15 (original name was: gnl|Prokka|FHMHNFEJ_15); gnlProkkaFHMHNFEJ_16 (original name was: gnl|Prokka|FHMHNFEJ_16); gnlProkkaFHMHNFEJ_17 (original name was: gnl|Prokka|FHMHNFEJ_17); gnlProkkaFHMHNFEJ_18 (original name was: gnl|Prokka|FHMHNFEJ_18); gnlProkkaFHMHNFEJ_19 (original name was: gnl|Prokka|FHMHNFEJ_19); gnlProkkaFHMHNFEJ_20 (original name was: gnl|Prokka|FHMHNFEJ_20); gnlProkkaFHMHNFEJ_21 (original name was: gnl|Prokka|FHMHNFEJ_21); gnlProkkaFHMHNFEJ_22 (original name was: gnl|Prokka|FHMHNFEJ_22); gnlProkkaFHMHNFEJ_23 (original name was: gnl|Prokka|FHMHNFEJ_23); gnlProkkaFHMHNFEJ_24 (original name was: gnl|Prokka|FHMHNFEJ_24); gnlProkkaFHMHNFEJ_26 (original name was: gnl|Prokka|FHMHNFEJ_26); gnlProkkaFHMHNFEJ_27 (original name was: gnl|Prokka|FHMHNFEJ_27); gnlProkkaFHMHNFEJ_28 (original name was: gnl|Prokka|FHMHNFEJ_28); gnlProkkaFHMHNFEJ_29 (original name was: gnl|Prokka|FHMHNFEJ_29); gnlProkkaFHMHNFEJ_30 (original name was: gnl|Prokka|FHMHNFEJ_30); gnlProkkaFHMHNFEJ_31 (original name was: gnl|Prokka|FHMHNFEJ_31); gnlProkkaFHMHNFEJ_32 (original name was: gnl|Prokka|FHMHNFEJ_32); gnlProkkaFHMHNFEJ_33 (original name was: gnl|Prokka|FHMHNFEJ_33); gnlProkkaFHMHNFEJ_34 (original name was: gnl|Prokka|FHMHNFEJ_34); gnlProkkaFHMHNFEJ_35 (original name was: gnl|Prokka|FHMHNFEJ_35); gnlProkkaFHMHNFEJ_36 (original name was: gnl|Prokka|FHMHNFEJ_36); gnlProkkaFHMHNFEJ_37 (original name was: gnl|Prokka|FHMHNFEJ_37); gnlProkkaFHMHNFEJ_38 (original name was: gnl|Prokka|FHMHNFEJ_38); gnlProkkaFHMHNFEJ_39 (original name was: gnl|Prokka|FHMHNFEJ_39); gnlProkkaFHMHNFEJ_40 (original name was: gnl|Prokka|FHMHNFEJ_40); gnlProkkaFHMHNFEJ_41 (original name was: gnl|Prokka|FHMHNFEJ_41); gnlProkkaFHMHNFEJ_42 (original name was: gnl|Prokka|FHMHNFEJ_42); gnlProkkaFHMHNFEJ_43 (original name was: gnl|Prokka|FHMHNFEJ_43); gnlProkkaFHMHNFEJ_44 (original name was: gnl|Prokka|FHMHNFEJ_44); gnlProkkaFHMHNFEJ_45 (original name was: gnl|Prokka|FHMHNFEJ_45); gnlProkkaFHMHNFEJ_46 (original name was: gnl|Prokka|FHMHNFEJ_46); gnlProkkaFHMHNFEJ_47 (original name was: gnl|Prokka|FHMHNFEJ_47); gnlProkkaFHMHNFEJ_48 (original name was: gnl|Prokka|FHMHNFEJ_48); gnlProkkaFHMHNFEJ_49 (original name was: gnl|Prokka|FHMHNFEJ_49); gnlProkkaFHMHNFEJ_50 (original name was: gnl|Prokka|FHMHNFEJ_50); gnlProkkaFHMHNFEJ_51 (original name was: gnl|Prokka|FHMHNFEJ_51); gnlProkkaFHMHNFEJ_52 (original name was: gnl|Prokka|FHMHNFEJ_52); gnlProkkaFHMHNFEJ_53 (original name was: gnl|Prokka|FHMHNFEJ_53); gnlProkkaFHMHNFEJ_54 (original name was: gnl|Prokka|FHMHNFEJ_54); gnlProkkaFHMHNFEJ_55 (original name was: gnl|Prokka|FHMHNFEJ_55); gnlProkkaFHMHNFEJ_56 (original name was: gnl|Prokka|FHMHNFEJ_56); gnlProkkaFHMHNFEJ_57 (original name was: gnl|Prokka|FHMHNFEJ_57); gnlProkkaFHMHNFEJ_58 (original name was: gnl|Prokka|FHMHNFEJ_58); gnlProkkaFHMHNFEJ_59 (original name was: gnl|Prokka|FHMHNFEJ_59); gnlProkkaFHMHNFEJ_60 (original name was: gnl|Prokka|FHMHNFEJ_60); gnlProkkaFHMHNFEJ_61 (original name was: gnl|Prokka|FHMHNFEJ_61); gnlProkkaFHMHNFEJ_62 (original name was: gnl|Prokka|FHMHNFEJ_62); gnlProkkaFHMHNFEJ_63 (original name was: gnl|Prokka|FHMHNFEJ_63); gnlProkkaFHMHNFEJ_64 (original name was: gnl|Prokka|FHMHNFEJ_64); gnlProkkaFHMHNFEJ_68 (original name was: gnl|Prokka|FHMHNFEJ_68); gnlProkkaFHMHNFEJ_69 (original name was: gnl|Prokka|FHMHNFEJ_69); gnlProkkaFHMHNFEJ_70 (original name was: gnl|Prokka|FHMHNFEJ_70); gnlProkkaFHMHNFEJ_71 (original name was: gnl|Prokka|FHMHNFEJ_71); gnlProkkaFHMHNFEJ_72 (original name was: gnl|Prokka|FHMHNFEJ_72); gnlProkkaFHMHNFEJ_74 (original name was: gnl|Prokka|FHMHNFEJ_74); gnlProkkaFHMHNFEJ_75 (original name was: gnl|Prokka|FHMHNFEJ_75); gnlProkkaFHMHNFEJ_76 (original name was: gnl|Prokka|FHMHNFEJ_76); gnlProkkaFHMHNFEJ_77 (original name was: gnl|Prokka|FHMHNFEJ_77); gnlProkkaFHMHNFEJ_78 (original name was: gnl|Prokka|FHMHNFEJ_78); gnlProkkaFHMHNFEJ_79 (original name was: gnl|Prokka|FHMHNFEJ_79); gnlProkkaFHMHNFEJ_80 (original name was: gnl|Prokka|FHMHNFEJ_80)

Compact view

gnlProkkaFHMHNFEJ_25 - Region 1 - RRE-containing

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Location: 13,404 - 33,667 nt. (total: 20,264 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaFHMHNFEJ_65 - Region 1 - HR-T2PKS

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Location: 1 - 32,032 nt. (total: 32,032 nt) Show pHMM detection rules used

Region on contig edge.

HR-T2PKS: (hr-t2pks-ksa and (t2fas or APE_KS2 or ketoacyl-synt))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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NRPS/PKS domains

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaFHMHNFEJ_66 - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 10,004 nt. (total: 10,004 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaFHMHNFEJ_67 - Region 1 - ranthipeptide

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Location: 8,240 - 25,407 nt. (total: 17,168 nt) Show pHMM detection rules used

Region on contig edge.

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaFHMHNFEJ_73 - Region 1 - NRPS

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Location: 1 - 42,186 nt. (total: 42,186 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 42186:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Ile - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg73_14

Search NORINE for peptide: strict or relaxed

AMP-binding (457..845): Ile

nrpys: Ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DASFLGGVYK
Nearest Stachelhaus code(s):: Ile DALFMGGVYK (56% 8Å match)
Stachelhaus code match:: 80% (moderate)

AMP-binding (1479..1869): X

nrpys: Asp, Asn, Glu, Gln, Aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DMKNLGTVSK
Nearest Stachelhaus code(s):: Asp DMKDLGMVDK (53% 8Å match)
Stachelhaus code match:: 70% (weak)