LOCUS       c00003_gnlPro..        12344 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FHMHNFEJ_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:46:58
            Original ID  :: gnl|Prokka|FHMHNFEJ_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12344
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12344
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5822:9050]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5823..9050
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..12344
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12344
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             612..1328
                     /locus_tag="ctg3_1"
                     /transl_table=11
                     /translation="MSETAKEPKKISKRSSEEKIEIIVAIFLGITALATAWASWIGSLH
                     GGNQATNYTKSNNLSSEGNSMWNEASQNLMQDMITWNDINEANLNYQYAESKNDKAEME
                     KYQYQIDQLMSDNCTEEFLEAINWAMDQKENVTPFMKDGYTESYFAEAQATIEESDKLL
                     EQGKKDNANGDAFGLVSVIYSVVLFMLGIVGTFKNLPNRRIVLGVAVAGFILATIYMFT
                     IPMPTGFNILSYFGMA"
     CDS             1532..1849
                     /locus_tag="ctg3_2"
                     /transl_table=11
                     /translation="MENKEKTTTPEMPDIDVLFELADLFKVFGDSTRLRIMYTISENEM
                     SVLNIAEALSMEQSTISHQLRVLRQNKLVRVRREGKQIYYSLDDDHVKRIIEMGLDHVL
                     E"
     CDS             1862..4186
                     /locus_tag="ctg3_3"
                     /transl_table=11
                     /translation="MRYKYQLDNLNCANCAGKIEAKIAETDGFEDVSFNFATKLLNFKS
                     EKQNPVSEIQAICDSIEDGVTVVDKTPKTNLKKYTYTLDNLNCAHCAGKIEAKITETDG
                     FEDVSFNFATKLLNFKSEKQNPISEIQSICDSIEDGVTVVDKTPKNDITTKAEPEITKK
                     KINRDTIFLAISIVLAVVSEILHLTLDGVTAVHYVVLAACFVATLLSGYKVFIKGAKNI
                     LKLRIDETTLMAVAVIAAFCLGDFVEAAMVTILFSIGEIFEDRAVDASRRDIEKLANIR
                     PDTATIIVDGAEQIVPAESVEIGSIIEVKPYERVPLDGIIIKGKTTLDTSALTGESLPV
                     DAGEGSEVLSGAINGSNLITVKTTKHFGDSTATRILQLVEDAAAQKGNSEKLISRFASV
                     YTPVVVLIAVAIAVIPPLCGLGAFSEWLYRALVCLVASCPCAIVISVPLSYYSGIGAAS
                     EVGVLIKGGKYIEALAKADTFVFDKTGTLTSGKLSVNKVNTVGSYSADEVLALAAASEK
                     YSAHPIASAIREKANGLKLPELSDYSESAGHGTSAVYNGKTIQCGGSKILSDEQKKIAN
                     KDDSVFVIYDGQLIGSLNVSDTVRPEAKEVISQLKALGVKNTVMLTGDRQQPAENVKNE
                     LGLSECHAELLPAQKLELFKGLKSKSKGACFVGDGINDAPVLSASDCGIAMGFGSEAAI
                     EASDAVLASGTLKQLPKAIKIARSVINTVKGNIIFALSIKALVIILAAFGLAQIWMSVI
                     ADTGVSVVCVLIAARLLKKKY"
     CDS             4385..5626
                     /locus_tag="ctg3_4"
                     /transl_table=11
                     /translation="LKKIFLLLVPALFLLSLYGCNTSSSSNNPTEQTTVTNTDDLSLDS
                     DIETTELNHDFEIYNNGKKVDTLNLYGLFKQIDNGFIYSKINKDSPNEMEYYRYYFDKK
                     SSVKLGSIKDWSMQIHDKAYVNNHLCFTSSTGDITDEENRTLEFIDIDLNKNKMTTVFS
                     DKGGFPYDTVTGADNLVIITKVLDNGTSLELYDTETQKFKQLKYLEFDDKNSIGETIRK
                     VSIDKSTKTISLLVLDCISQNEASLKIETYDYDMNFLKSYDISNISDDSNELIQGVQVF
                     DFKNNYLFYQNFSITRCIGYIDSDKLKKSDISEDVDDTFSIVSASEDDSDTNLLYKRAE
                     SSSENNYIYLFDTTNKTMKETKFNIEEKGYTIGGISRIGKDNLMILMSPDNADKKSDLN
                     SRIYFTKLSDLKFQ"
     CDS             5823..7445
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.7e-43, bitscore:
                     137.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHTNEEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             7458..7949
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_6"
                     /sec_met_domain="ALS_ss_C (E-value: 3e-30, bitscore: 93.7,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQDPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRVNTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             8010..9050
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_7"
                     /sec_met_domain="IlvN (E-value: 5.6e-84, bitscore: 269.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 4.3e-61, bitscore: 194.7,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLK
                     DSGCDVIIGLYEGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKLAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(9605..11443)
                     /locus_tag="ctg3_8"
                     /transl_table=11
                     /translation="MKKFLPIAMAAVMSMSAVAVSAVSANAVEPLNTPVQYAQVARASL
                     ATPKISKAESVYGGVKLTWNKVNGAAKYRVYYKGRKGWTRMVDTTSTSYVDKDVSSGRN
                     YTYTVRCISADGKSFTSGYDSKGTAVKYIAAPEISKLENVNGGVKISWGKVSGATKYRV
                     YYKGSKGWTRMVDTTSTSYIDKDVSSGRNYTYTVRCITSDAKKFTSGYNPTGKSVKYVA
                     TPKISKLEVTYDGVKLTWNKVAGAEKYRVYYKDRNGWTKLADTTGTTMLDMNVVSKEFD
                     LSIDDIYYTVRCISKDAKSFTSGYDSKGTPIGDHQDCPEIYSIGAVNNGVEMHWTGDAP
                     KFRVYIKENGSWKKIAETYDNYYVHKGAKSGSNTYTVRGVSKDGKKFTTMFNPTGVTYR
                     YKTSDKTRDAYINYMMNHQSEWMPSLGSEHNLSGVMFLDFDFDGVPELVAQKADSNEYS
                     FHSVVYKFEDGKLKRVGNVNDGFAIYYNKTAKKYEVHDLKISLNVDDGYYWSGNSIITY
                     DGENLFANMYSARGVGEESNNNIYYRYFDGNDKNISRAKYNEINLKQFNNCVNAHMFTE
                     FIATGYGDASVWGEKTTAENKQSLLDAYNSFSYEKY"
     CDS             complement(11640..12317)
                     /locus_tag="ctg3_9"
                     /transl_table=11
                     /translation="MKKFLTALIAFVMCFSVVTTAFAATPDEISESDVASEIRQVMIDT
                     YYGGKEPEYLSIEIVGSTSDGGVYFMHNEGFSLDYSIEEIIGDYTYHYNHNDDVMLYKN
                     GNVYSIKEAYESGVIDDSILEELSKMNFGLESNKPNTTVPTEPTTSVATVDEPVTVPDT
                     TSATSATKPVSTSNTATKDTPNNSQNNSGAVQTGQNSVAVILLVAMLAGCAVIFAKRRN
                     YFK"
ORIGIN
        1 atatagtgta taagtaaaaa tcaaaaatta tacgaatcta aaattcataa tgagaactaa
       61 tttgttacat tttattaaaa acgaacccac tcggttacgc agatgtaatt taacaattct
      121 cttacagaaa atgatactac aaaattgtag taaagtcaac ggaataataa aactgtaatc
      181 tatttttggg caagttgtac tcaaattatt aatttgttgc tttttttgtt tttaatataa
      241 ccaaccatgc tttttaaaac cgttttttcc taaaaagaag taattaatca aagcgatttt
      301 ttgtaaaatt attacaaatt gaaacagtta ttatattttc ctaattgaaa atttgcaggc
      361 aaatctatcg tatatattta ttctttgcaa atcaaacgaa taaaacaaaa atatctaaag
      421 gtaaattttt ttaaaaatca cagacaaaat gattattatg ccgaaaaaaa gactttactg
      481 ccacttgcat tgaatttaaa acttttatca attatgattg aaacagaatc agtcggcaag
      541 tgtcctttta caatataata acgacaaaat taaggcattg cggcaaattt ttaattaacg
      601 ggggattcag aatgagcgaa acagcaaaag aaccgaaaaa aataagtaaa agaagcagtg
      661 aagaaaaaat tgaaattatt gttgcgattt ttctcggaat aaccgcactc gccacagcat
      721 gggcatcgtg gataggttca cttcacggcg gaaatcaggc gactaactac acaaaaagca
      781 acaacctctc atcagagggc aactcgatgt ggaatgaggc ttctcaaaat cttatgcagg
      841 atatgatcac atggaatgac atcaatgagg caaaccttaa ttaccaatat gcggaatcta
      901 aaaacgataa agcggaaatg gaaaaatatc agtaccaaat tgatcagctt atgagtgata
      961 actgtacaga agaatttctt gaggcaatta attgggcaat ggatcaaaag gaaaatgtaa
     1021 ctccgtttat gaaggacggt tacaccgaaa gttattttgc agaggcacaa gctacaattg
     1081 aagagtcgga caaacttctt gaacaaggta agaaagataa cgcaaacggt gacgcattcg
     1141 gtcttgtaag cgtaatttac tcggttgtac tctttatgct cggtatcgta ggcacattca
     1201 agaatcttcc gaacagaaga attgtgctcg gtgttgcagt tgcaggtttt attcttgcca
     1261 ctatatatat gtttacaatt ccgatgccga caggattcaa tattctcagt tatttcggaa
     1321 tggcataaaa caaaatattc agtactcaca gcggtgaaag caaatgcttt tgccgctgtt
     1381 tttttgtaaa aaatcaaaaa aacattacat tttttcgtgt gtgtctattg actttttaaa
     1441 aagggaatgc tatattataa ttaacatatg agcatatctt catatgttca agtataacta
     1501 ttaacctgag agaaaattaa aggggacgcc tatggaaaac aaagaaaaaa caaccactcc
     1561 cgaaatgccc gacattgatg tgctgtttga gcttgcagac ctttttaagg ttttcggtga
     1621 ttcaacccga cttcgcatta tgtacaccat ttcggaaaat gaaatgtcgg tgctcaacat
     1681 tgctgaagct ctcagcatgg agcaaagcac aatttcccac caactgcgtg tgttaaggca
     1741 gaacaagctg gtgcgtgttc gccgtgaagg aaagcagatt tattacagcc ttgacgatga
     1801 ccatgtgaaa cgaatcatag aaatgggact tgaccatgtt cttgaataag gagggagaca
     1861 tatgaggtac aaatatcagc ttgacaatct caactgcgct aattgtgcag gcaagattga
     1921 ggctaaaatt gcagaaacag acggctttga ggatgtgagc tttaattttg cgacaaaact
     1981 tctcaacttc aaaagcgaaa agcagaatcc tgtttccgaa attcaggcaa tttgcgacag
     2041 cattgaggac ggtgtaaccg ttgttgacaa aactccgaaa accaatctca aaaaatacac
     2101 ctacacttta gacaatctca attgtgctca ttgtgcgggc aaaattgagg ctaaaattac
     2161 agaaacagac ggttttgagg atgtaagctt taattttgcg acaaaacttc tcaacttcaa
     2221 aagcgaaaag cagaatccta tttccgaaat tcagtcgatc tgcgacagca ttgaggacgg
     2281 tgtaactgtt gttgacaaaa ctccgaaaaa tgatatcaca acaaaggcag aacccgaaat
     2341 cacgaaaaag aaaatcaacc gtgacacaat cttccttgca atttcaattg tacttgctgt
     2401 agtgtccgaa attctccacc ttacacttga cggtgttaca gctgttcatt atgttgtact
     2461 cgcagcgtgt tttgttgcaa cacttctttc gggttacaag gtatttatca agggtgcaaa
     2521 aaacattcta aagctgagaa ttgacgaaac aacgcttatg gctgttgcgg taattgcggc
     2581 attctgtctt ggagattttg ttgaggcggc aatggtaaca atcctctttt ctatcggtga
     2641 aatttttgag gatcgagcag ttgacgcatc ccgccgtgac attgaaaagc ttgcaaacat
     2701 tcgtcccgat acagcaacaa ttattgttga cggtgcggaa cagattgttc ctgccgaaag
     2761 cgttgaaatc ggaagtatca ttgaagtcaa gccatacgaa agagttccgc ttgacggcat
     2821 tattatcaaa ggtaaaacaa ctctcgacac atcggctctc acaggcgaaa gccttcctgt
     2881 tgatgcaggc gagggcagtg aggtactcag cggcgcaatc aacggcagta accttattac
     2941 cgtcaaaacc acaaaacatt tcggcgacag taccgcaaca agaattcttc agcttgttga
     3001 agatgccgcc gctcaaaagg gcaacagcga aaagcttatt tcaagatttg cctctgttta
     3061 cacacctgtt gttgtactca ttgcagttgc aatcgcagta attcctccgc tttgcggact
     3121 cggagcattc agcgaatggc tctaccgtgc gcttgtttgt cttgtagcgt catgtccgtg
     3181 tgctattgtt atttccgtac ctctctctta ctattcgggt atcggtgcgg catccgaagt
     3241 cggtgtactc atcaagggcg gaaaatatat tgaggctctt gcaaaagcag acacattcgt
     3301 attcgataaa acaggcacac tcacaagcgg caagctcagc gtaaacaagg ttaatactgt
     3361 cggttcatac agtgctgacg aagttcttgc tcttgccgct gcaagcgaaa aatattctgc
     3421 tcatccgatt gcctccgcaa tcagagagaa ggcaaacggt cttaaactcc ccgagctttc
     3481 cgactacagc gaaagtgccg gtcacggaac aagcgcagtt tataacggca aaactattca
     3541 gtgcggcggt tcaaagattc tttcggacga acagaagaag attgcaaaca aagacgattc
     3601 tgttttcgta atttatgacg gtcagcttat cggttcgctc aatgtcagcg atacggtaag
     3661 acctgaggca aaagaggtta tctcacagct taaagcgctc ggtgtcaaga acacggtaat
     3721 gctcacgggc gacagacaac agcctgccga aaatgttaaa aatgaactcg gactttccga
     3781 atgtcacgca gagcttctcc ctgctcaaaa gcttgaactt ttcaagggct tgaaatcaaa
     3841 atccaagggt gcttgctttg taggcgacgg catcaatgat gcccctgttc tttcggcaag
     3901 cgactgtggt atcgcaatgg gattcggcag tgaagccgct attgaagcgt cagacgcagt
     3961 tctcgcatca ggcacactca aacagcttcc aaaggcaatt aaaattgcaa gaagtgttat
     4021 caacactgtc aagggcaaca tcatctttgc cctctcaatc aaggctcttg taattatcct
     4081 cgccgcattc ggtcttgcac aaatctggat gtccgttatc gccgacacag gcgtaagcgt
     4141 agtctgcgta ctcatagccg caagactcct caaaaagaaa tattgatttt tttgcaaatc
     4201 atatcattta ttatgataaa gcaccgtgag ctttcacaag tttcacggtg ctttcatttg
     4261 ccaaaatttt tctaaatata atcttatatt atagtatttt taaatcattg acttttataa
     4321 ttatgtaaat tataatattt ttgtcagcgc ttgtaactga taaataaact tcggagagat
     4381 taatttgaaa aagatatttt tattattagt acccgcttta tttttacttt cattatacgg
     4441 gtgtaacact tcttcatcaa gcaataaccc cactgaacaa acaaccgtaa cgaatacaga
     4501 tgatttatct cttgattcag atattgaaac aacagaatta aatcatgatt ttgaaattta
     4561 caataacggc aaaaaggtgg atactttaaa tctttacggc ttatttaaac aaattgataa
     4621 cggcttcata tattcaaaaa tcaataaaga ctctccaaat gaaatggaat attacagata
     4681 ttattttgat aaaaaaagca gtgtaaaact cggctcaata aaagactggt ctatgcaaat
     4741 tcacgataaa gcttatgtaa ataatcacct ttgctttacg tcaagcacgg gcgacattac
     4801 agacgaagaa aacagaactc ttgaatttat tgatatcgac cttaataaaa acaaaatgac
     4861 gactgtattt tctgacaaag gcggatttcc atatgacact gttacaggag cagacaatct
     4921 tgtcataatc acaaaagtgc tagacaacgg tacttctttg gaactgtatg ataccgaaac
     4981 tcaaaaattc aagcaattaa aatatttaga gtttgatgat aaaaacagta tcggggaaac
     5041 tataagaaaa gtttcaattg acaaaagtac aaaaacaatc tctcttttgg ttttggattg
     5101 catttcacag aacgaagctt ctttaaaaat agaaacttat gactatgata tgaattttct
     5161 caaaagctat gatatttcca acatttcaga tgattcaaac gaattaattc agggcgtaca
     5221 ggtttttgat tttaaaaaca attatctatt ctatcaaaat ttcagcataa caagatgtat
     5281 aggatatata gacagcgata agctgaaaaa atccgacata tcagaagatg tagatgatac
     5341 tttttcaata gtatccgcat ctgaagatga cagtgataca aatttattgt ataagagggc
     5401 ggaatcaagt tcagaaaata actacatata tctttttgat acaaccaaca aaacaatgaa
     5461 agaaacaaaa tttaatattg aagaaaaagg gtacactata ggcggtatat cacggatagg
     5521 aaaagataat ttgatgatat tgatgtcccc tgataatgca gacaaaaaaa gtgaccttaa
     5581 ttcaagaata tactttacaa aactaagcga cttaaaattt cagtaaacag gcggtaaaaa
     5641 tcaattaaaa tccattttgc aaattatctg tcaaaatcct gcaaaaaatt taatttatgg
     5701 gcaatactgc tctttacttt ttaaggtatt tattgtataa ttagcggtaa agtaaaaagg
     5761 tatatttaat gttacaaaac accttttgct cacaataaaa aggataggag ggacaaaaca
     5821 taatgatcag cggtgctgaa attatggtaa aatgtttgga agccgagggc gttgacatag
     5881 tctttggtta tcccggtgcg gctatttgcc cattttacga taaagtttac gattcgagca
     5941 ttacccacat tcttgttcgt caggaacaga acgctgctca tgcggcaagc ggctatgcaa
     6001 gatgcagtaa tcgtcccggt gtttgcgtgg caacttccgg tcccggtgca accaacctca
     6061 tcacaggcat tgcaaccgcc tatacggact ctattccgat tgttgccatt acaggtcagg
     6121 ttcgttccga ccttctcggc agagatgtct ttcaggaagc tgacatcaca ggagcttgtg
     6181 aaccgtttgt aaagcacagt tatctcgtca gcaaaacaga agaccttccg agagttttca
     6241 aagaggcttt ccatattgcc tcaaccggca gacccggtcc tgtacttatc gacattcccg
     6301 ttgatattca ggaaaatgaa attgaaagtt ttgaatatcc cgaaagcgta aacattatcg
     6361 gttacaagcc gaacactaag ggacacgcaa ttcaggttaa aaaggctgtt gaggccatca
     6421 acgcaagcaa gcgtcctgtt atcgtatcag gcggcggcgt gctgagttcg ggtatcaagc
     6481 ttaaacttca aaaatttgca gaaactacgg gtatccccgt tatttcaact atgatgggca
     6541 tcggtgttat gcccagcgag catgagcttt atctcggaat gctcggcact cacggcaagg
     6601 ctgttgccaa ccgtgctctt cacgaagccg accttgtaat cgtatgcggt gcaagactcg
     6661 gtgacagagc tgttgcggct cccgaccaga tgagtgaaaa cacaaaggta attcacattg
     6721 acattgaccc tgctgaaatc ggtaagaatg ttaaaacaga aattccgatt gtaggcgata
     6781 tgaaaaatgt catcaatatg ctgcttgaca gtatcggcga ttacaaggtt acaacaatgt
     6841 ggagcgaaac cgtaaagaac tggaaaaaag acctttaccg tgagcctccc gtatttgacg
     6901 gctttgttga gccgagaaca cttgtcggtc atctcagcgc aatgttccgc tcgaaggcaa
     6961 ttcttgttgc cgatgtagga caaaatcaaa tctggtgtgc aaacaacttc cgtattcgtg
     7021 agggcagatt cctcacaaca ggcggtatgg gtacaatggg ttactcaatt cccgctgcaa
     7081 tcggtgcaaa gtttgcaaga cccgaccgtg acgttattgt aatctgcggt gacggcagtt
     7141 ttcagatggg gcttaatgag cttgcgacta ttgcaggcaa tcagctcgga attaaaatca
     7201 tcattatgaa aaacgcacga ctcggaatgg ttcgtgaact tcaggacaaa cactacggtg
     7261 gcagacactc cgcaacaatt ctcaacggtg atcccgactt cttgaagatt gccgatgctt
     7321 acggcattga ccatgcagag gctcatacaa acgaggaagc cgaaaacatc atcaagggta
     7381 ttgttgattc ggaaaaaccg ttcattcttg tttgcgatgt tcaccccgac actccgtcaa
     7441 tttaatgagg tgataaaatg cagtatacat tatcaatact tgttgaaaat caggcgggcg
     7501 ttctttcaaa gatttcggga cttttctctc gccgaggctt taacatcgac tcgcttgcag
     7561 taggtgttac tcaggacccg tcggtttccc gaatcacaat cgttgcaaac ggtgacgagt
     7621 acattgttga acagcttgaa aaacagctca acaagctcat tcccgttatt aaggtaaaaa
     7681 ggcttaacga gggcgaattt atcagccgtg agcttgtttt aatcaaggtt cactgcgccg
     7741 cctcaaaaag agccgaaatt gtcaaaacgg ttgaaattat gcaggcgaaa atcgttgatg
     7801 tatccccttc gtcagttacc gttgagtact gcgaatgcgc aagccgcgtc aacacgcttg
     7861 ttgacttact caagccttat ggtatccgtg agattgtaag aacaggtact gttgccattg
     7921 acagaggcac agcttcggtt tccgtttaat cttacagtta gcatatattc taatttatat
     7981 gccgcgtttg cggtaaggag gactttaata tgaaagacta cacaaagaac atgacagcac
     8041 caatctacta tcagtcagat tgcaaccttg accttctcaa gggtaagaaa attgctatta
     8101 tcggttacgg cagccagggt catgcacacg ctctcaacct caaggattca ggttgcgatg
     8161 taatcatcgg tctttacgaa ggtagcaaga gctgggcaaa ggctgaagct cagggcttta
     8221 aggtatatac atcggcagag gctgcaaagc aggctgacat catcatgatt cttatcaacg
     8281 atgaaaagca ggcagctctt tacaagaacg acatcgagcc aaacctcgaa gcaggcaata
     8341 tgcttatgtt cgctcacggc tttaacattc acttcggttg catcaagcct ccaaaggatg
     8401 ttgatgttac aatggtagct cctaagggac ctggtcacac agttcgttca gagtatcagg
     8461 ttggtaaggg tgtaccttgc ctcgttgctg ttgagcagga cgctacaggt caggctaagg
     8521 atctcgcact tgcatatgca ctcggtatcg gcggtgcaag agccggcgtt cttgaaacaa
     8581 cattcagaac agaaacagaa acagacctct tcggtgaaca ggctgttctt tgcggcggtg
     8641 tttgtgcact tatgcaggca ggttttgaaa cactttgcga tgccggttac gacccaagaa
     8701 atgcttactt tgagtgtatc catgagatga agctcatcgt tgaccttatc tatcagtcag
     8761 gttttgcagg catgagatat tcaatctcta acacagctga gtacggtgac tacatcacag
     8821 gtccaaagat catcacagag gatactaaga aggctatgag aaaggttctt tctgacattc
     8881 aggacggtac atttgctaag gacttcctcc ttgacatgag cgatgcaggt tcacaggttc
     8941 acttcaaggc tatgagaaag ctcgctgctg aagctcctgc cgaagtattc ggtaaggaag
     9001 ttagaaagct ctacagctgg tctgacgagg ataagctcat caacaactaa tgttttttag
     9061 ttcgtgaaga cagtttgata tattcaaact tcggtcaccc gaacattaca tagtataaat
     9121 taacggttca gtcaatttgg ctgaaccgtt ttttgtaggg gcgcactgta ttcgtcggca
     9181 agtaaaggca taaattcgat accaaatcca attatataaa aatcacaaat ttactgataa
     9241 tccgtagcgg cgaacctcgt tcgccaatcg aaccgattgt aaaatcggtt cgactcaaca
     9301 caaactattc gtttattaat atatcatttt catataacaa aagctgtgta tatgttcggt
     9361 ttgtttttgc aaacaaaccg attggcgaac acggttcgcc gctacagtag aacaatcaca
     9421 ttgcgacatt tataaaatta catttgtaaa ttgttttgtg ccattacttg cgggcgggta
     9481 ataatctccc gtctgaaatt tataattttc cactttctgc ttttcatttt ccatttaaaa
     9541 aatcagggtt cagcttttta cggctgaacc cttttgcagt taaaacttat caatttttaa
     9601 ataatcaata cttctcatag gagaaagaat tatatgcgtc aagcaaagac tgcttattct
     9661 cagcggtagt tttctcaccc catacgctgg catcaccata acctgtcgca ataaattcgg
     9721 taaacatatg tgcatttacg caattattaa actgtttaag gttaatttcg ttatattttg
     9781 cccgtgaaat atttttgtca ttaccgtcaa aatatctata ataaatatta ttatttgatt
     9841 cttcgcctac gcctcttgcc gaatacatat ttgcaaaaag attctctccg tcgtatgtga
     9901 ttattgaatt acccgaccaa tagtaaccgt catctacatt taaagatatc tttaggtcgt
     9961 gaacctcata ctttttggca gttttattat agtatatcgc aaaaccgtcg ttaacatttc
    10021 ccactctttt taacttaccg tcttcaaatt tgtaaacaac ggaatggaaa ctatactcat
    10081 tggaatcagc cttttgtgca acaagctccg gaactccgtc aaagtcgaaa tccaaaaaca
    10141 taacacctga caaattgtgt tcacttccca agcttggcat ccattcactc tgatgattca
    10201 tcatataatt gatataagca tcccttgttt tatcggatgt cttatatctg tatgttacac
    10261 cggttgggtt aaacatcgta gtaaactttt taccgtcttt tgaaacacct cttaccgtat
    10321 aagtgttact gccggacttt gcacccttgt gaacataata gttgtcataa gtttctgcta
    10381 tcttcttcca agaaccgttt tctttaatat aaacacggaa ctttggcgca tctcccgtcc
    10441 aatgcatttc aacaccgttg tttactgcac caatgctgta aatttcggga caatcctgat
    10501 gatcgccaat gggcgtaccc tttgaatcgt agccgcttgt aaaactcttg gcatccttgc
    10561 tgatacaacg aaccgtgtaa taaatatcat caatgcttaa atcaaattcc tttgaaacaa
    10621 cattcatatc aagcatagtc gtgcctgttg tatcggcaag ctttgtccaa ccgtttctgt
    10681 ccttgtagta cacacgatat ttttcagcac ctgcgacctt gttccatgtc agctttacac
    10741 cgtcatatgt aacctcaagt tttgaaattt tcggtgtggc aacatacttt accgacttgc
    10801 ctgtcgggtt ataaccgctt gtgaatttct ttgcgtctga tgtaatacat cttacagtat
    10861 aagtgtaatt tctgcccgat gaaacatcct tgtcgatata tgaggttgaa gttgtatcga
    10921 ccattcgtgt ccagccttta ctgcctttgt agtaaactct gtatttagtt gcaccgctta
    10981 ctttgcccca agagattttt acaccgccgt ttacattttc aagctttgaa atttcggggg
    11041 cggcaatata ttttacggct gttccctttg aatcataacc gcttgtaaag ctctttccgt
    11101 cagcagaaat acatcttaca gtataggtgt aattcctgcc cgatgaaaca tccttgtcga
    11161 catatgaggt tgaagttgta tcaaccattc gtgtccaacc tttacggccc ttgtagtaaa
    11221 ctctgtattt agccgcaccg ttcactttgt tccatgtaag ctttacacca ccgtaaacac
    11281 tttcggcttt tgaaattttc ggtgttgcca agcttgccct tgcaacctgt gcatactgca
    11341 caggtgtgtt tagcggttca accgcatttg cagaaactgc cgaaaccgca accgcagaca
    11401 tcgacattac cgccgccatg gctataggta aaaacttttt catatctatc cctcgctttg
    11461 taaatattct acgcattatt aagaactttt gctaaatttt tatgcaagtt aattgtaaca
    11521 ttaaatgata taaaaagcaa tacatcttga taaactatca caaattttta agctaaaata
    11581 aataaaccgt tcacaaaagc gagaacggtt tattttatat attctgttga tgttttgaat
    11641 tatttaaaat aatttctgcg ttttgcaaaa attactgcac aacctgcaag cattgcaaca
    11701 agaagaatta cagcaacgct gttctgtcct gtctgtacag caccgctgtt attctgtgaa
    11761 ttgttcggtg tgtcctttgt agctgtgttg cttgttgaaa caggcttagt tgccgaagtt
    11821 gcagaagttg tatcgggtac tgttacaggt tcgtcaactg ttgcaaccga agttgtaggc
    11881 tcagtaggaa cagttgtatt cggtttatta gattccaaac caaaattcat ttttgacaat
    11941 tcttcaagaa tactatcatc aataactccg ctttcataag cctctttaat tgagtaaaca
    12001 ttgccattct tataaagcat aacatcatcg ttatggttgt aatgataagt atagtcacca
    12061 attatttctt caattgaata atcaaggcta aagccttcat tgtgcataaa atatactccg
    12121 ccgtcacttg ttgaaccaac aatttcaatg ctgagatatt caggctcttt accaccgtaa
    12181 tatgtatcta tcatcacctg tctgatttct gatgcaacat ccgattctga tatttcgtca
    12241 ggtgtagccg caaaagctgt tgttacaacc gaaaagcaca ttacaaatgc tatcaatgct
    12301 gttaaaaatt ttttcatttt tatttcctca ccttttattt attc
//
