LOCUS       gnlProkkaKEDLBAPG_67   11714 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KEDLBAPG_67.
ACCESSION   gnlProkkaKEDLBAPG_67
VERSION     gnlProkkaKEDLBAPG_67
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 22:21:01
            Original ID  :: gnl|Prokka|KEDLBAPG_67
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11714
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11714
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[125:1714]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      126..1714
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..11714
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11714
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             126..266
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg67_1"
                     /sec_met_domain="TIGR03973 (E-value: 3.1e-28, bitscore:
                     87.3, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 3.9e-28, bitscore: 87.0,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHIKTLNTKNLQNTVKKGGCGECQTSCQSACKTSCTVGNQSCEQ
                     K"
     CDS             347..1714
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg67_2"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.5e-29,
                     bitscore: 92.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1e-16, bitscore: 51.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 8.8e-15, bitscore: 45.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.3e-20, bitscore:
                     62.7, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLIHRYKSNGFNIVLDINSGCIHLVDEVTYEVLPYLEEGLGTEA
                     IAEKLENKYNREDIETSVRECNKLKEDGMLFTKDVYENVIEEFSNNRQTVVKALCLHIA
                     HDCNLACRYCFAEEGEYHGRRALMSYEVGKKALDFLIANSGSRKNLEVDFFGGEPLMNW
                     QVVKDLVKYGREQEKLHNKKFRFTLTTNGVLLNDEVMEFCNKEMGNVVLSVDGRKEVHD
                     YMRPFRKGAGSYDLIMPKFQKFAESRNQDKYYVRGTFTHHNLDFSKDVLHLADLGFKQI
                     SVEPVVAADTEEYAIREEDIPQIMEEYDTLAKEMIKREKEGKGFNFFHFMIDLTGGPCV
                     YKRLSGCGSGTEYLAVTPWGDFYPCHQFVGEEQYLMGNVDEGITKPEIQKEFGGCNVYT
                     KKDCKDCFARFYCSGGCAANAFHFQGDIKGNYEIGCELQRKRVECAIMIKAALACD"
     CDS             1826..4234
                     /locus_tag="ctg67_3"
                     /transl_table=11
                     /translation="MKKSKGIVVLLLTLILTVFFCFTAAVGIGPTGTGAAKHINTGLDL
                     AGGVSITYQAKESNPTSEEMSDTIYKLQKRVEQYSTEAQVYQEGSDRITVEIPGVTDAD
                     TILNDLGKPGSLYFITKEDADGNQNFTTGQDGYVLSRTMDEIKESGSVVLEGSDVADAQ
                     GGAIQNQNTSAKEYVVSLTLTSDGENSGKTKFAEATKNNVGKQIAIVYDNNIISAPNVN
                     EEISGGKAQISGMSDLEEAQNLASYIRIGSLGLELEELRSSVVAAQLGEEAISTSVLAG
                     AIGLIIVIIFMIIAYRVPGVVAGIALILYTSLMLITLNAFDITLTLPGIAGIILGIGMA
                     VDANVIIYARIREEIGAGVSVRNSIKSGFSKAFSAIFDGNITTLIAAFVLMWLGSGTVK
                     GFAYTLALGIVISMFTALVVSRLIVNALYAVGVRDPKFYGSAKERKAVDFLGKKKVFFA
                     ISIILILCGPAAMFANSHAGNKALNYSLEFSGGTSTTVTFNEDMDIKTIDSEVTPVVEE
                     VTGDKNVQPTKVVGTNQVVIKTRSLNQSEREALQSALVEKFGVDDSTISTESISSTVSS
                     EMRRDAIVAVIVATICMLLYIWFRFKDIRFASSAVLALLHDVLVVLAFYAIARVSVGNT
                     FIACMLTIVGYSINATIVIFDRIRENLHSGSREKLAEIVNTSITQTLTRSIYTSFTTFV
                     MVAVLYIMGVSSIREFAAPLMVGVLVGAYSSVCITGALWYVMKKKFAGKGQPAIAAASA
                     SAKSSSKPKKARDVSQKDPTQPKKKNRKRVAERLAAEEAAKKQQNDDAE"
     CDS             4316..6028
                     /locus_tag="ctg67_4"
                     /transl_table=11
                     /translation="MEKWVIAAKRADFNQIGQQFHIDPVIARLIRNRDVIGEDKIREYL
                     SGTVQELPSPWLMKDMEKAVDILEKKISQKAKVRIIGDYDIDGVTSTYILMKGLARIGA
                     DVDTYIPDRVADGYGIHAHLIERAETDRIDTIVTCDNGIAAAAEIQMAKDKGMTVIITD
                     HHEVPYREEKGERQMVLPPADAILNPKQYDCPYPNKNLCGAVVAFKYIAALYERFGVPA
                     EELEDYYELAAIATVGDVMDLQGENRILVKEGLYRLRNTKNQGLQELIRANSLEDAKIT
                     AYHIGFVLGPCINASGRLDTAARSLALLNAKTKEEAARLAGDLTALNQSRKALTEKGKE
                     EAIRIIETTELKNDRVLVVYLPDCHESLAGIIAGRIREKYHRPAFVLTGGETSAKGSGR
                     SIESYSMYEELVKCADLMIQFGGHPMAAGLSIEEKNIEEFRRRLNVNCTLTDEELRPKI
                     VIDVPMPVSYITKELVEQISLLEPFGKGNTKPVFAQKNLRVLDYSIIGKNKNVLKLKLL
                     DPQGISVEGIYFGEAEDFVNFIREKDSISVTYYPEINRFRGRESLQIIIQNYC"
     CDS             6176..6700
                     /locus_tag="ctg67_5"
                     /transl_table=11
                     /translation="MKKIEDYVLSIPDFPEPGIIFRDITSVLQDADGLQLAIDSMQDCL
                     KDIDVDVIAGTESRGFIFGVPIAYNLHKPFVPIRKKGKLPRETVSVSYDLEYGSAEIEM
                     HKDSIKPGQKVVIVDDLIATGGTIEAAIKLVEQLGGEVVKVVFLMELAGLKGRERLNGY
                     DVASVICYDGK"
     CDS             6738..9068
                     /locus_tag="ctg67_6"
                     /transl_table=11
                     /translation="MTEITKSTEAKKDEMQVEKEKLESVKRADAAVKTMHDFTSPEVLY
                     KELINSVLKYHPSTDISMIEKAYKVASEAHEGQKRKSGEPYIIHPLCVAIILADLELDK
                     ETIVAGLLHDAVEDTWMTYEEVEKEFGSEVALLVDGVTKLGQLSYSADKVEVQAENLRK
                     MFLAMAKDIRVILIKLADRLHNMRTLQYMRPEKQQEKARETMDIYAPIAMRLGISKIKV
                     ELDDLSLKYLKPDVYYDLVHKVALRKSEREQFVGAIVKEVKKHMDDANIKAQVDGRVKH
                     FFSIYKKMVNQDKTIDQIYDLFAVRILVDTVKDCYAALGVIHEMYKPIPGRFKDYIAMP
                     KPNMYQSLHTTLIGPNGQPFEIQIRTYEMHRTAEYGIAAHWKYKESSDGKAPVGKSEEE
                     KLNWLRQILEWQRDMSDNKEFMSLLKNDLDLFADSVYCFTPQGDVKTLPSGSTPVDFAY
                     SVHSAVGNKMVGARVNGKLVPIEYEIKNGDRIEIITSQNSQGPSRDWLKLVKSTQAKNK
                     INQWFKKELKEDNILKGKEMLAQYARAKGFKIANYTKTQYLEAVLRKYGFRDWDSVLAA
                     IGHGGLKEGQVFNKLVEAYDKENKKNLTDEQVLEAASETQEKLHIAKSKSGIVVKGIHD
                     VAVRFSKCCNPIPGDEIVGFVTRGRGITIHRTDCVNVLNMSETDRTRLIEAEWQQPDTK
                     EKEKYMAEIQVYANNRTGLLVDLSKIFTERKIDLRSINSRTSKQEKATISMSFEIGSKE
                     ELRSLIEKIRQVESVIDVERTTG"
     CDS             9133..9762
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     163.1; E-value: 9.6e-50)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg67_7"
                     /transl_table=11
                     /translation="MKNLELQKCILGPVYTNCYLLKNKETGELIIVDPADCPEKIEMKI
                     SRMNGKPVAILLTHGHFDHILAAQAVKEKYNIPIYACRQEEEMLREPSINMTVHYGQGC
                     SIVPDVFLEDLDVIRLAGFSVQMIHTPGHTKGSCCYYLKDEGVLFSGDTVFYGSVGRTD
                     FPGGSTAEIVRSLHKLVDSLPEETEVFPGHDASTTIGYEKRYNPFV"
     CDS             9755..11269
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg67_8"
                     /sec_met_domain="PF04055 (E-value: 5.3e-25, bitscore: 78.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCKIGILFENRDFEHDVYELIKAFYPEAEIHTLYENAEAEYDLRF
                     SVEWDNDSYIIKYERTENLSKQETEQKGVISADILSKENAGCGIQDAHALRKENKDTIK
                     YALYQLLVKLTGRTLPWGNLTGIRPAKLAMGMIESGMKNTEAAREMRERYLVSPQKTAL
                     AITIANREREILKDIDYENGYSLYIGIPFCPSICLYCSFSSYPLKVWEKRTDEYVEALC
                     REVRETALMMKGRKLDTIYIGGGTPTTLLPHQIRKLLDTVGEAFGYEGLAEFTVEAGRP
                     DSITREKLMAIREYPVTRISVNPQTMNQETLDIIGRRHTVEQTKEAFHLARELGYDNIN
                     MDLIVGLPGEDIHMVERTLEQVRELAPDSITVHSLAVKRAARLNIFKEKYQEMSFENNQ
                     EIMDLTMKTAYEMGMGPYYLYRQKNMKGNFENVGYAKVDKAGIYNILIMEEKQPIIALG
                     AGGSSKLVFDHGQRIERVENVKDVSNYISRIDEMIERKRTAIATWL"
ORIGIN
        1 aacttttttt atgtgcaccg gcggtggaac actgggggga atgctgtcgt tattaaaagc
       61 ttttaaaatg ataagttata tgatatacta tgcctagaat ataattacat aaggaggtta
      121 gagttatgga acatatcaaa accctgaata caaagaattt acagaacact gtaaaaaaag
      181 gtggatgtgg cgagtgccag acttcctgcc agtccgcatg taaaacttcc tgtacagtag
      241 gaaaccagag ctgcgagcag aaataagatc agctatggag aaatgagata agcagcggaa
      301 cttttattcc gctgcttatc ttacgcttag aaaggatttt agtaaaatga gtctgattca
      361 ccgttataaa agcaatggct ttaatattgt actggatatc aacagtggat gcatccatct
      421 ggtagatgag gttacatatg aggttcttcc atatctggaa gagggccttg gcacagaagc
      481 tattgcagag aaactggaaa acaaatataa cagagaagat attgagacat ctgtaagaga
      541 atgtaataag ctgaaagaag atggaatgct ttttacaaaa gatgtttatg agaatgtaat
      601 tgaagaattt tcaaataacc ggcagaccgt tgtaaaagca ttgtgcctgc acattgctca
      661 tgactgcaat ctggcctgcc gttattgttt tgccgaagaa ggcgaatatc atggcagaag
      721 agctcttatg tcctatgaag tcggcaaaaa agctcttgat ttcctgatcg cgaactccgg
      781 ttccagaaaa aacctggaag tagatttctt tggcggcgag ccgctgatga actggcaggt
      841 tgtaaaagat ctggtaaaat atggcagaga gcaggaaaag cttcacaata agaaattccg
      901 tttcacttta acaacaaacg gagttcttct gaatgatgaa gtaatggaat tctgcaataa
      961 agagatgggc aacgttgtac tgagtgtgga cggacgtaag gaagtacatg attacatgcg
     1021 tccattcaga aaaggtgcag gaagctatga cctgatcatg ccgaagttcc agaagtttgc
     1081 agaatccaga aatcaggaca agtattatgt aagaggtact tttactcacc ataatcttga
     1141 tttctccaag gatgtgcttc atctggcaga tcttggattc aaacagattt ctgtagagcc
     1201 tgtagttgcg gctgatacgg aggaatatgc gatccgcgag gaggatatcc cccagatcat
     1261 ggaagagtat gatactcttg caaaagaaat gattaaaaga gagaaagagg gaaaaggatt
     1321 taacttcttc cattttatga tcgaccttac aggtggccct tgtgtataca agagactgtc
     1381 aggctgcggt tcaggaacag agtacctggc tgtaacaccc tggggtgatt tttacccatg
     1441 tcaccagttt gttggtgaag aacagtatct catgggaaat gtagacgaag gcatcacaaa
     1501 gccggaaatc cagaaggaat tcggcggatg caacgtttac acaaagaaag actgcaaaga
     1561 ctgcttcgca cgtttctact gtagtggcgg atgtgcggca aatgcattcc atttccaggg
     1621 agatatcaaa ggcaattatg aaatcggatg cgaactccag agaaaacgtg tggagtgcgc
     1681 catcatgata aaagccgcac tggcatgtga ttagtgggca gtaatctgtc tgactgatac
     1741 cgccgtcggc tgttatcata acagaaaatg gctggcaggc ggatgaacat gaccgcggac
     1801 aaaaaatcaa gaagggaaaa gaactatgaa gaaaagtaaa ggaatcgtag tgctgcttct
     1861 gacactgatc ctgactgtgt tcttttgctt tactgcagcc gtaggtatcg gtcctaccgg
     1921 aaccggtgca gcaaaacata tcaacacggg tcttgatctt gccggtggtg tcagcattac
     1981 ctaccaggct aaggagagca atccgacaag cgaagagatg tcagatacga tctacaagct
     2041 tcagaagcgt gtagagcagt acagtactga ggctcaggta taccaggaag gatcagaccg
     2101 tattacagtt gaaattcctg gtgttacaga tgcagatact attttgaatg atctgggtaa
     2161 accaggttcc ctgtatttca tcacaaaaga agatgctgac ggaaaccaga actttactac
     2221 aggacaggat ggatatgttc tctccagaac tatggatgag atcaaggaat ccggaagtgt
     2281 tgttctggaa ggttctgatg tagcagatgc ccagggtggt gcgatccaga atcagaacac
     2341 aagtgcaaag gaatatgtgg taagtcttac tcttacttct gatggagaaa acagtggtaa
     2401 aacaaaattt gcagaagcta caaagaataa tgtaggcaag cagatcgcta tcgtctatga
     2461 caataacatt atcagtgctc cgaatgtaaa tgaagagatt tccggcggaa aagcacagat
     2521 cagcggaatg tctgacctgg aagaagcaca gaaccttgct tcttatatcc gtatcggttc
     2581 tctgggactg gaactggaag aacttcgttc cagtgttgta gctgcacagc ttggtgaaga
     2641 agcaatctct acaagtgttc ttgcaggtgc gatcggtctg atcatcgtta ttatctttat
     2701 gatcattgca taccgcgtac ctggtgtagt tgcaggtatc gcactgattc tttatacatc
     2761 attaatgctg atcacgctga atgcctttga tattactctt actcttccgg gtattgcggg
     2821 tattattctt ggtatcggta tggcggtgga tgccaatgtt attatttatg cccgaatcag
     2881 agaggaaatt ggtgcaggag tttcagtaag gaattctatt aagtccggtt tcagcaaagc
     2941 tttctctgca atctttgatg gaaatattac aacactgatc gcagcctttg tgctgatgtg
     3001 gcttggttca ggtactgtta agggatttgc ttatacactt gcccttggta tcgtgatctc
     3061 catgtttaca gcactggttg tatccagact gattgtaaat gcactttatg cagttggtgt
     3121 acgtgatccg aaattctacg gatctgcaaa agaacgtaag gcagttgatt tccttggaaa
     3181 gaagaaagta ttttttgcta tttccattat cctgatcctc tgcggtccgg cagcgatgtt
     3241 tgctaattcg catgcaggaa acaaagcgtt aaattacagc cttgagttct caggcggtac
     3301 ttctacaact gttacattta atgaagatat ggatattaag accattgatt ctgaagtaac
     3361 tcctgttgta gaagaggtga caggagataa aaatgttcag cctacaaagg tagtcggaac
     3421 aaatcaggtt gtgatcaaga cacgttctct gaatcagagc gaacgtgaag ctctgcagag
     3481 tgcactggtt gagaaatttg gtgtagatga cagcacgatt tccacagaaa gtatttcttc
     3541 tacagtaagt agtgaaatgc gtcgtgatgc gatcgtagcc gttatagtag ctacaatctg
     3601 tatgcttctt tatatctggt tcagatttaa agacatccgt tttgcaagca gtgcggtatt
     3661 ggcgcttctg catgatgttc tggttgtact tgcattctat gctattgcca gagtatctgt
     3721 cggtaataca tttattgcct gcatgcttac aatcgtaggt tattctatca atgctacaat
     3781 cgttattttt gaccgtatac gtgagaacct tcacagtggt tccagagaaa aactggcaga
     3841 aattgtaaac acaagtatca ctcagactct tacaagaagt atttatacct cttttacaac
     3901 ttttgttatg gtagctgttc tttatatcat gggtgtttct tctatccgtg aatttgcagc
     3961 acctctgatg gttggtgttc ttgtcggtgc atattcttct gtatgtatta caggtgcgtt
     4021 gtggtatgtg atgaaaaaga aatttgcagg aaaaggacag ccggcaattg ctgcagcttc
     4081 cgcatctgca aagtcctctt caaagccgaa gaaagcacgt gatgtatcac agaaagatcc
     4141 gactcagcca aagaagaaaa acagaaaaag agtagctgaa cgtctggctg ccgaagaagc
     4201 agctaaaaaa cagcagaatg atgatgctga ataaaacaat aattgtctga aaaacaggca
     4261 gacagaaata tcccggggta aaactccggg atatttttat gaggagagaa aatatatgga
     4321 gaaatgggta atagcagcaa aaagagcaga ttttaaccag atcggtcaac agtttcatat
     4381 tgatccggtg attgcgagac tgatcaggaa cagagatgtg atcggagaag ataagataag
     4441 agagtatctg tcaggaacag tacaagagct tccttctccc tggctgatga aggatatgga
     4501 aaaagctgta gatatcctgg agaaaaaaat atcgcagaaa gcaaaagtcc gtattattgg
     4561 tgattatgat attgatggtg tgacctctac atacatttta atgaaaggcc ttgcgaggat
     4621 cggagcagat gtggatactt atattccgga cagagttgca gacggatatg ggattcatgc
     4681 acatcttata gaaagagcgg aaacggaccg gatcgatacg atcgtgacct gtgataatgg
     4741 aattgctgcg gctgctgaaa tccagatggc aaaggataag ggaatgacag tgattattac
     4801 agatcatcat gaggttcctt acagggagga aaagggagaa cgccagatgg tgcttccgcc
     4861 ggcagatgcg attttgaatc cgaaacaata tgattgtcca tacccgaata aaaacctgtg
     4921 tggggcagtg gtggccttta aatatattgc agcactttac gagagatttg gtgttccggc
     4981 agaggagctg gaagattatt atgaactggc ggctattgca acagtaggag atgttatgga
     5041 tcttcaggga gagaacagga ttctggtaaa agaaggactg taccgtctga gaaataccaa
     5101 aaatcaagga ttgcaggaac tgatccgagc aaattctctg gaagatgcta aaatcacagc
     5161 ttatcatatc ggatttgtgc tgggaccatg tatcaatgcc agtggaagac tggatacagc
     5221 tgcccgttct cttgcacttc tcaatgcaaa aacaaaggaa gaagcagcaa ggcttgccgg
     5281 agatcttaca gctcttaatc agagccgaaa agctctcact gagaaaggaa aagaagaggc
     5341 aatccggatt atagagacta cagagctgaa aaatgacaga gtactggtag tttatcttcc
     5401 ggattgtcat gaaagtcttg ccggtattat agcaggcagg atcagggaaa aatatcacag
     5461 gccggccttt gtattgacgg gcggtgagac aagtgcaaaa ggaagcggaa gatcaataga
     5521 aagttactct atgtatgaag aactggtaaa atgtgcagac ctgatgatac agtttggagg
     5581 tcatccgatg gcagcaggtc tttctataga agaaaaaaat atagaagaat tccggagacg
     5641 cctcaatgtc aactgtacgt tgacggacga agaattgcgt cctaagatcg tgattgatgt
     5701 gccgatgcct gtgtcttata ttacaaaaga actggtagaa cagatttcgc ttctggaacc
     5761 ctttggaaaa gggaatacaa aaccggtctt tgcacagaaa aatctcagag tgcttgatta
     5821 cagtattatc gggaaaaata aaaatgtact aaaattaaaa cttctcgatc cgcaggggat
     5881 ttcagtggaa ggcatttatt tcggagaagc agaggatttt gtgaacttta tcagggaaaa
     5941 agacagtatt tctgttactt attatccgga gatcaacaga ttcaggggac gagagagtct
     6001 tcagattatt attcagaatt actgttaata ttaccgcttg gtttgtaacc gccggtaagc
     6061 ctggaaatac aaatgtcagg gcttaacagt aacttgattc tgaaataaaa aggtgatata
     6121 ctataaaata tttatgagcg aacagcaata taacacacac tggaggagaa ataaaatgaa
     6181 gaaaattgaa gattatgtat taagtatacc ggattttcct gaaccgggga ttattttcag
     6241 agatattaca agtgttctgc aggacgcgga tggcctgcag ttggcaatcg actccatgca
     6301 ggactgtctt aaggatatag atgtggacgt gattgcagga acagagtcca gaggctttat
     6361 ctttggtgta ccgatcgcat ataatcttca taaaccattt gtaccgattc gtaaaaaagg
     6421 taaacttccc cgcgaaacag tatctgtaag ctatgatctg gaatatggca gtgcagagat
     6481 tgaaatgcat aaagattcca taaaaccagg tcagaaagtg gttatcgttg atgatctgat
     6541 cgcaacaggc ggtacgatcg aagcagcgat caagctggtg gaacagcttg gcggtgaggt
     6601 tgtcaaggtt gtatttctca tggaacttgc aggtttaaag ggacgcgaaa gactgaatgg
     6661 gtatgatgta gcgtctgtaa tttgttatga tggtaaataa gcacagctga ttgtgcagga
     6721 caggcaggtg ggagcatatg acagagataa caaaaagtac agaagcaaaa aaagatgaaa
     6781 tgcaggttga aaaagagaag ctggaatctg taaagagagc agatgcggca gtaaagacca
     6841 tgcatgattt tacaagtccg gaggtgcttt ataaagaact gataaacagt gttctgaagt
     6901 atcatccatc aacagatatt tccatgatag agaaggcata taaggttgca agtgaagctc
     6961 atgaaggaca gaagagaaag tctggagagc catatatcat tcatcctttg tgtgttgcca
     7021 tcattctggc agatctggaa cttgacaaag aaacgatagt tgcaggtctt cttcatgatg
     7081 cagttgaaga tacctggatg acctatgagg aagtggagaa ggaatttggt tcagaggttg
     7141 cacttcttgt ggatggtgtt accaagttgg gacagttatc ttattctgcg gataaagtag
     7201 aagttcaggc agagaacctc agaaagatgt ttcttgccat ggctaaggat atcagagtta
     7261 ttctgatcaa gcttgcagac cgtcttcata atatgcgtac cttacagtat atgcgtcctg
     7321 aaaagcagca ggaaaaggcc agagagacca tggatattta tgctcctatt gccatgcgtc
     7381 tgggtatttc caagataaag gtagagctgg atgacctgtc gctgaaatac cttaagccgg
     7441 atgtatatta tgacctggtg cataaggttg ccctgcgtaa aagcgagaga gaacagtttg
     7501 taggtgcgat tgtaaaagaa gttaagaaac atatggatga tgccaatatt aaggcgcagg
     7561 tggacggacg tgtaaaacac tttttcagca tctacaagaa gatggtaaat caggataaga
     7621 ctattgatca gatttatgat ttatttgctg tccgtattct tgtagataca gtgaaggatt
     7681 gttatgctgc ccttggtgtg atccatgaga tgtataagcc aattccggga cggtttaaag
     7741 attatattgc catgccgaaa cccaatatgt atcagtcatt gcataccaca ttgatcggac
     7801 ccaacggaca gccctttgaa atccagatcc gtacttatga aatgcacaga actgcagaat
     7861 atggtatcgc tgcacactgg aaatataagg agtcgtctga cggaaaggct cctgtaggta
     7921 agagtgagga agagaaactg aactggctgc gtcagattct ggaatggcag agagacatgt
     7981 ctgataacaa agaattcatg agtcttctga agaatgacct ggatcttttt gcggacagtg
     8041 tttactgttt cactccacag ggagatgtta aaacacttcc aagcggttct acaccggtgg
     8101 attttgcgta cagtgttcac agtgcagtcg gaaataagat ggtaggtgcc agagttaacg
     8161 gtaagctggt tccgattgaa tatgagatca aaaacggcga ccgtattgaa atcattactt
     8221 cacagaattc tcagggacca agccgcgact ggttgaaact ggttaagagt actcaggcaa
     8281 agaacaagat taaccagtgg ttcaagaagg aattaaaaga agataatatc cttaagggca
     8341 aggagatgct tgcgcagtat gcgcgtgcaa agggatttaa gatcgcaaat tatacaaaaa
     8401 cccagtatct ggaggctgtt ttgcgtaaat atggtttcag ggactgggat tcagtacttg
     8461 ctgcaattgg tcatggcgga ttgaaagaag gtcaggtttt caataagctg gtagaggctt
     8521 atgataagga aaataagaag aatctgacag atgagcaggt tcttgaggct gcttctgaga
     8581 cacaggagaa gcttcacatt gccaagagca agagtggaat tgtggtaaaa ggaatccatg
     8641 atgtggcagt ccgtttttcc aagtgctgta atccgatccc gggtgacgag attgtaggct
     8701 ttgttacaag aggacgtgga atcacaatcc atcgtacaga ttgcgtcaat gtgctgaata
     8761 tgtctgagac ggacaggaca cgattgatcg aggcggaatg gcagcagcct gataccaagg
     8821 aaaaagagaa gtatatggct gagattcagg tttatgcaaa taaccgtaca gggcttcttg
     8881 tggatctttc taaaatattt acagaacgta agatcgacct gcgaagtatt aacagccgta
     8941 caagcaagca ggagaaggca actatttcca tgagttttga gattggaagc aaagaggaac
     9001 tgcgttccct gatcgagaag atccgtcagg tagagagtgt cattgacgta gagagaacta
     9061 caggctgatc atggaaaaat ctgctggaac attattttat ggaactgctg cagattgaca
     9121 gaaaggaata acatgaagaa tttagaatta cagaaatgta tattaggacc tgtatataca
     9181 aattgctatc tccttaagaa taaagaaacc ggagaactga tcattgttga tcccgcagat
     9241 tgtccggaga agattgaaat gaagatttcc cggatgaatg gaaaaccggt ggcgattctt
     9301 cttacccatg gacattttga ccacattctg gctgcacagg cagtaaagga gaaatataat
     9361 attccgattt atgcctgtcg tcaggaagag gagatgctcc gcgaaccttc gatcaatatg
     9421 actgtacatt atggacaggg atgttctatt gtgccggatg tatttctgga ggatctggat
     9481 gttatcagac tggcgggatt ttccgttcag atgatccata caccgggaca taccaaagga
     9541 agctgctgtt attatctgaa agatgaaggt gtattgttca gcggtgatac agtgttctat
     9601 ggctctgttg gaagaacgga ttttccgggt ggaagtacag cagaaatcgt gagaagtctc
     9661 cataaactgg tagattcgct tcctgaagag accgaggttt tccccggaca tgatgcatct
     9721 accactattg gttatgaaaa gaggtataat ccatttgtgt aaaataggca ttctgtttga
     9781 gaacagagat tttgaacatg atgtttatga actgatcaaa gcgttttatc ccgaagcgga
     9841 gatacatact ctttatgaaa atgctgaagc agagtatgac ctccgcttca gtgtggaatg
     9901 ggacaatgac agttatatca taaaatacga aaggacagag aatctgtcga aacaggaaac
     9961 agagcaaaaa ggggtaattt ccgcagacat actttctaaa gagaatgcag gctgtggaat
    10021 acaggatgct catgctctga gaaaagagaa taaagatact atcaaatatg ctttgtatca
    10081 gttgttggta aaactgacgg gcagaactct tccatgggga aatctgacag gaatacgtcc
    10141 tgccaaactg gcaatgggaa tgatcgaatc cggaatgaaa aatacggaag cagcccggga
    10201 gatgcgtgag agatatctgg taagtccgca gaaaacagcg cttgccatca ctattgcaaa
    10261 cagggaaaga gagattctga aggatattga ctatgaaaat ggatacagcc tttatattgg
    10321 aatcccgttt tgcccaagta tctgtctgta ttgttccttc agctcctatc cgctgaaagt
    10381 gtgggagaag agaacagatg aatatgtgga agctctctgc cgggaggtaa gagagactgc
    10441 tcttatgatg aagggaagaa aactggatac catctatatt ggcggcggta ccccgactac
    10501 actgcttcca catcagatcc gtaagctcct ggatacagtg ggagaagctt ttggctatga
    10561 aggactggca gagtttactg tggaagccgg cagaccggac agtattacac gtgaaaagct
    10621 gatggcgatc agggagtatc cggtaacaag aatttccgta aatccacaga ctatgaatca
    10681 ggagaccctg gatattatcg gccgcagaca tactgtggag cagacaaaag aagcgtttca
    10741 tctggcacga gagctgggat acgataacat taacatggat ctgatcgtag gactcccggg
    10801 tgaggatatt cacatggtag agcggactct tgaacaggtt cgtgaactgg caccggacag
    10861 tattaccgta cattcactgg cagtgaaacg tgcagcaagg ctgaatattt ttaaagagaa
    10921 atatcaggaa atgtcttttg agaataatca ggagattatg gatctgacca tgaaaactgc
    10981 gtatgaaatg ggaatgggtc cttattatct gtacagacag aagaatatga agggaaattt
    11041 tgaaaatgtt ggctatgcaa aggttgacaa agcgggaatt tacaatatac tgattatgga
    11101 ggaaaaacag cctatcatcg cactgggggc aggcggttct tccaagctgg tctttgacca
    11161 tggacagaga attgaacgtg tggagaatgt aaaagacgtt tctaattata tttcccgcat
    11221 tgatgagatg atcgagagaa aacggacagc aatagctacc tggctgtagg atgtggaggt
    11281 aacattttgg acacagtaca aaagacagca gcaggttcac agcagaggat cctggaattt
    11341 gaccttgctt ctgaactgca tcatggaatg ctggtaagta atctggctta tgcggttgca
    11401 gaggagatgg gactgccgca tgaacagtgt tatgagcttg caatagcagg aatgctccat
    11461 gatataggaa agctgaagct gacaagttat attaacggac aggagcagga tcctctggtg
    11521 atcgaggaac tgaagtatgt ccggatgcat tctgcattgg gatatgagga acttaaaggg
    11581 cagggatatt cggattttgt attggagagt atcctgtacc atcatgagaa ttatgatggt
    11641 agtggatatc cgtccaataa agcaggtgat gatataccca taggtgcccg gatactcaga
    11701 gtctgcgatg tata
//
