LOCUS       gnlProkkaOKBNLKHF_65    8385 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OKBNLKHF_65.
ACCESSION   gnlProkkaOKBNLKHF_65
VERSION     gnlProkkaOKBNLKHF_65
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 22:28:23
            Original ID  :: gnl|Prokka|OKBNLKHF_65
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8385
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8385
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[2299:4498]"
                     /cutoff="5000"
                     /detection_rule="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /neighbourhood="20000"
                     /product="HR-T2PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2300..4498
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /neighbourhood="20000"
                     /product="HR-T2PKS"
                     /protocluster_number="1"
     cand_cluster    1..8385
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /kind="single"
                     /product="HR-T2PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8385
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="HR-T2PKS"
                     /region_number="1"
                     /rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /tool="antismash"
     CDS             complement(25..1086)
                     /locus_tag="ctg65_1"
                     /transl_table=11
                     /translation="MKKVILTGDRPTGRLHVGHYVGSLKERVKLQNSGEYDDIYLMIAD
                     AQALTDNAEHPEKVRQNILQVALDYLACGIDPNKSTIFVQSMIPELTELTFYYMNLVTV
                     SRVQRNPTVKAEIQMRNFEASIPVGFFCYPISQAADITAFRATAVPVGEDQLPMLEQCK
                     EIVHKFNSVYGETLTEPQIILPSNKACLRLPGIDGKAKMSKSLGNCIYLAEEPEDIKKK
                     VMSMFTDPNHLRVEDPGKVEGNPVFIYLDAFCRDEYFAEFWNDYSCLDELKAHYQRGGL
                     GDVKVKKFLNNVMQEELRPIRERRKEWENHLPDVLDILKEGSKVAKETAAKTLEDVRHS
                     MRIDYFTDNNLLK"
     CDS             1329..2015
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141:acyltransferase (Score: 83.7; E-value: 2e-25)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg65_2"
                     /transl_table=11
                     /translation="MEYNYHKNAGQLAFIKFVKGLVHLLIRPKVEWKDKSLKKSLKGKP
                     VVFVCNHTHHFDGVVISSVLSRYKPYMLVKKSWYDKSGTGSFIRICRSIPVDFDTMDTN
                     WYAQSEGAVENGYSMLIFPEGGIAREGKMLPFKPGAALLAAKKGLDIIPIASLGEYKIL
                     FGKRQKILIGNPIKSECPENVRYSKYAKEISAEAEKQVKKLYLELEEKYGKGKVYYKED
                     FSSKNL"
     CDS             2056..2298
                     /NRPS_PKS="Domain: PP-binding (6-75). E-value: 1.1e-11.
                     Score: 37.0. Matches aSDomain:
                     nrpspksdomains_ctg65_3_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg65_3"
                     /sec_met_domain="PP-binding (E-value: 1.9e-12, bitscore:
                     37.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNAIADQIKEMLVENLRIPENILTYDSELFGDEIGLDSIDSIEI
                     VAGIDTLFGIDMTGADREHFQSIRALTEYVESKQG"
     aSDomain        2074..2280
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg65_3_PP-binding.1"
                     /evalue="1.10E-11"
                     /label="ctg65_3_PP-binding.1"
                     /locus_tag="ctg65_3"
                     /protein_end="75"
                     /protein_start="6"
                     /score="37.0"
                     /tool="antismash"
                     /translation="DQIKEMLVENLRIPENILTYDSELFGDEIGLDSIDSIEIVAGIDT
                     LFGIDMTGADREHFQSIRALTEYV"
     CDS             2300..4498
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (67-399). E-value:
                     9.2e-50. Score: 161.6. Matches aSDomain:
                     nrpspksdomains_ctg65_4_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: hr-t2pks-ksa"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: t2fas"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 80; E-value:
                     2.9e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_4"
                     /sec_met_domain="hr-t2pks-ksa (E-value: 2.4e-106, bitscore:
                     345.3, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="t2fas (E-value: 3.4e-23, bitscore: 71.4,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADKKRCVVTGLGLICGVGDNVKDCWDAVTLGHSGIDEVKSVDTS
                     NCYAHKGAEVDKASSELSPENYDRSSFLCIHAANEAFEDASIDASEKNIGVILGSCVGG
                     AASIDKYYTDEIKGDGGKKEDIFKMGASAIANNVSAHFGLEGITANIVNACAAGTMSIG
                     YACDLIREGKGDVFIAGGSDSFSSLAFSGFHALHALDENACSPFNHSTGITLGEGSGIL
                     VIESYEHAVERGAKIYCEILGSGVSSDAYHITAPRPDGEGQMSAIRRAVESSALTFDDI
                     DYINAHGTGTAKNDEAEFLSLHTLFDGNDHLSVSSTKSMTGHCLGAAGSIEAVFSVKAI
                     KENLVPPTIGYSDEDLKVLSEKAGNIDFIPNKSHTKDVHYAMSNSFAFGGNNASIIFSD
                     NEHDIPDNSRNEKIYITGISKLTGTKTDEHSLNCNLTSEDYDKHGIKVAFYRKLDRFSQ
                     LQLLSGMDALADADIKIDKDNEYKTGIVIGTADGPMTEIVDFQKKAITRGTEKGSAFSF
                     PNTVYNAAGGYLSIFSGIKGYNATVANGNQAGLQSICYAADILADGNESVMLAAGTDEN
                     TKTNLELYTKAELLEKPLGEGSVTLVLETEESANGRNARKYAEIKGYAQAHRPVSYDNS
                     EVDSKAVVEVIEKACVDAGIEADNIDFVCCDDRKIIKTLMPCYDVSQEIGNARAAASAM
                     TAAYAAELLSDSEKNYEYGLALSMGAGGTYSAVILKKA"
     aSDomain        2501..3496
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg65_4_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="9.20E-50"
                     /label="ctg65_4_PKS_KS.1"
                     /locus_tag="ctg65_4"
                     /protein_end="399"
                     /protein_start="67"
                     /score="161.6"
                     /tool="antismash"
                     /translation="DRSSFLCIHAANEAFEDASIDASEKNIGVILGSCVGGAASIDKYY
                     TDEIKGDGGKKEDIFKMGASAIANNVSAHFGLEGITANIVNACAAGTMSIGYACDLIRE
                     GKGDVFIAGGSDSFSSLAFSGFHALHALDENACSPFNHSTGITLGEGSGILVIESYEHA
                     VERGAKIYCEILGSGVSSDAYHITAPRPDGEGQMSAIRRAVESSALTFDDIDYINAHGT
                     GTAKNDEAEFLSLHTLFDGNDHLSVSSTKSMTGHCLGAAGSIEAVFSVKAIKENLVPPT
                     IGYSDEDLKVLSEKAGNIDFIPNKSHTKDVHYAMSNSFAFGGNNASIIFSD"
     CDS             4514..5248
                     /NRPS_PKS="Domain: PKS_KR (3-167). E-value: 2.7e-16. Score:
                     51.8. Matches aSDomain: nrpspksdomains_ctg65_5_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     227.2; E-value: 3.6e-69)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg65_5"
                     /sec_met_domain="adh_short (E-value: 2.4e-40, bitscore:
                     127.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 4.8e-35, bitscore:
                     111.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTALVTGSSRGIGKACALKLAELGYDIAVNCNSNLEMAQKAVD
                     EITSLGRKAVAYKANTADIDEVKDMFRSIQQDFGGIDVLVNNAGVVDDAYLLMIKDESL
                     ERSLDINIKGYFNCARQASLKMLRKKSGIIINISSVSSVLAVEGQSVYSATKGAVNAMT
                     HTLAKELAKYGIRVNAVAPGFIETEMMNGIPEELQKKYLEAIPEKRFGTVQDVANVVGQ
                     LCSDDFSYMTGQVLVLDGGLSL"
     aSDomain        4523..5014
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg65_5_PKS_KR.1"
                     /evalue="2.70E-16"
                     /label="ctg65_5_PKS_KR.1"
                     /locus_tag="ctg65_5"
                     /protein_end="167"
                     /protein_start="3"
                     /score="51.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGSSRGIGKACALKLAELGYDIAVNCNSNLEMAQKAVDEIT
                     SLGRKAVAYKANTADIDEVKDMFRSIQQDFGGIDVLVNNAGVVDDAYLLMIKDESLERS
                     LDINIKGYFNCARQASLKMLRKKSGIIINISSVSSVLAVEGQSVYSATKGAVNAMTHTL
                     A"
     CDS             5245..5700
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1270:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine
                     (Score: 94.1; E-value: 1.6e-28)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg65_6"
                     /transl_table=11
                     /translation="MMNLLEINQRIKQRPPFQMIERVTELEPNVSATGIKNVSVNEPYF
                     AGHFPDTPIMPGVLLIESAAQLCSLVFAPESVEEDKLYVLLKVKDFKMLRPVIPGDTLI
                     ISVNVTMSTKSAFEFACVIKVDGEVRAKGSLLFTTMDKNAVYKPSQE"
     CDS             5703..6407
                     /locus_tag="ctg65_7"
                     /transl_table=11
                     /translation="MKVLVLNGSPKGEKSNTLNITKAFLDGFSADTEIEYITVKKETIK
                     PCMGCFSCWSRTPGECVIKDDMQKIYEKINSADIIIESFPLYFFGMPSQMKALTDRCLP
                     YMLPYSGNVAEDKEASFHELRDEAMHEKRLLVITTCGYVSAEPMYPALTKQLDLICGNG
                     NYTMIKCPEGELFIAEKAERQRKAYLDSITEAGREFCENRCLCDETMKKISKPILSPKG
                     FEAITKAHWKMS"
     CDS             complement(6382..6990)
                     /locus_tag="ctg65_8"
                     /transl_table=11
                     /translation="MDANVTDLRIVKTRTNIKNSLIDLLAEKNVSKITVTELAEKAMIN
                     RKTFYRHYHTVQDVVDDINYDIINDVISHAKKSDRDGNNLVNQLNFIGLSIVENKEQIN
                     KILKNSPEVFGSGRSVELLKRFIEVSIRPVLNFKNETKLKYLVEFVVSGFISVYVRWFN
                     DGCAESSEKLADAVNEFVLGALSEYVPPEKLINSFSNEP"
     CDS             7055..7894
                     /locus_tag="ctg65_9"
                     /transl_table=11
                     /translation="MTGLIIEGGARRGIFTAGITDCLLENKIHFDYVAGVSAGAEVALD
                     FTAKQEGRSRRVIMPHRTGDFSVLGFLSMDLDNMIYRFPYQDYPFDFDTFFASDTNCEF
                     VATDCVTGKAKYFSENKSEQRLLDSVRASCTVPILYQISEFEGGKYVDGSVADAVPFDR
                     AFEQGCSRVLVLLTKPENEPCTDYRKFEFLINKKYKDYPNLINALMTRFDRYNEQCKRM
                     KQLEEDGILMVLRPSHKYVKSFEMNTDVLDEAYNAGKNLAKEKLAEIEDFLNVLEKK"
     CDS             8090..8254
                     /locus_tag="ctg65_10"
                     /transl_table=11
                     /translation="MKKQLMIFDFVCLGIGAIFLTFVAILQNCGINITNGSVIGIVITV
                     LLFILILLC"
ORIGIN
        1 gtattttaca tattgaattt taaattattt aagaagatta ttgtctgtaa aataatcgat
       61 tctcatagaa tgacggacat cctcaagtgt ttttgcggca gtttcctttg caaccttact
      121 gccctctttg agaatatcga gaacatcggg aagatgattt tcccattctt ttctgcgttc
      181 acgaatagga cgaagctcct cctgcataac attgttaagg aatttcttaa ccttgacatc
      241 accgagtccg ccacgctgat aatgagcctt gagttcgtca agacagctgt aatcattcca
      301 aaattcagca aaatactcgt cacggcagaa tgcgtcaagg tagataaaca cggggttgcc
      361 ctcaaccttg ccgggatcct caacacgaag atgattcggg tcggtaaaca ttgacataac
      421 ctttttcttg atatcctcgg gttcttctgc aagataaatg cagttgccga gggacttgct
      481 catctttgcc ttgccgtcaa tacccggcag tcgcagacaa gccttgttgc tcggaagaat
      541 aatctgcggt tccgtaagag tttcgccgta aacggaattg aacttgtgaa caatctcctt
      601 gcattgttca agcatcggga gctgatcctc gccgacagga acggcagttg cacggaatgc
      661 cgtgatatca gccgcctgac tgattggata acagaaaaat cccacaggaa tgcttgcctc
      721 aaaattacgc atctgaattt ctgccttaac ggtggggttg cgctgaacac gggacacggt
      781 tacgaggttc atataataga aagtaagctc tgtaagctcg ggaatcattg actgaacaaa
      841 aattgttgac ttgttcggat ctattccgca ggcaaggtag tcgagcgcaa cctgcaaaat
      901 attctgtctt accttttcgg gatgctcggc attgtcggta agagcctgag cgtctgcaat
      961 cataaggtat atatcatcat attcgcccga attctggagc tttactctct ccttgagcga
     1021 acctacatag tgaccgacat gaagtctgcc cgtaggacgg tcacctgtta aaattacttt
     1081 tttcataggt ttctcctttg tttaccttga ttcaaaggca aaattctttt ctatgattat
     1141 atcaccataa acaacagccg tcaacatttg taaaaaaggt aaaaagaaaa atattccata
     1201 ataattccca tatattttat gccacaaaat tcgacagaat gttgcataag acacacgcaa
     1261 aattcatttg accgttgaaa ttttttaaaa taaaaatata atattttaaa aaaacgaggg
     1321 taaagagtat ggagtacaat tatcataaaa atgcaggaca gcttgcattc ataaaatttg
     1381 taaaaggtct tgtgcatctt cttattcgcc ctaaggttga atggaaggac aagagcctta
     1441 aaaagagcct caagggcaag cctgttgtgt ttgtatgcaa ccacactcac cactttgacg
     1501 gagttgtgat aagctctgta ctcagcagat acaagccgta tatgcttgtt aaaaaaagtt
     1561 ggtacgacaa gagcggaaca ggctcgttta tccgaatttg ccgcagtatt cccgttgact
     1621 ttgacaccat ggacacaaac tggtatgcac aaagtgaggg tgcggttgaa aacggatatt
     1681 caatgcttat cttccccgag ggcggaattg caagagaggg caaaatgctc ccgttcaagc
     1741 ccggtgcggc attgcttgcg gcaaaaaaag gtcttgacat aatcccgatt gcatctttgg
     1801 gtgaatataa aattcttttt ggaaagaggc agaaaatttt aatcggcaat ccgataaaat
     1861 ccgaatgtcc cgaaaatgtt cgctactcaa aatatgcaaa agaaataagt gccgaagccg
     1921 aaaagcaggt caaaaagctt tatcttgagc ttgaagaaaa atacggcaaa ggcaaggttt
     1981 attacaaaga agatttttct tcgaaaaatt tataataaaa tcaaaacact aaaaatttta
     2041 agtgaggtaa ttaaaatgaa caatgctatt gcagatcaga ttaaggaaat gctcgtagaa
     2101 aaccttagaa ttcccgaaaa cattcttaca tacgattcag aacttttcgg tgacgaaatc
     2161 ggtcttgact caatcgactc aatcgaaatc gttgcaggca tcgacacact tttcggtatt
     2221 gatatgacag gtgcagaccg tgagcacttc caatcaatca gagcacttac agaatatgta
     2281 gaaagcaagc agggttaata tggctgacaa aaagagatgt gttgtcacag gactcggact
     2341 tatctgcggc gtcggtgaca atgtaaagga ttgctgggat gccgtaacac tcggtcactc
     2401 cggcattgat gaggttaagt cggttgacac ctcaaactgt tatgcacaca agggtgcaga
     2461 ggttgacaag gcatcgtcag agctttctcc cgaaaactat gaccgttctt cctttctctg
     2521 tattcatgcc gcaaacgagg cttttgaaga tgcaagcatt gacgcatccg aaaagaacat
     2581 cggtgttatt cttggcagtt gtgtaggcgg tgcggcaagc attgacaaat attacacaga
     2641 cgaaatcaag ggtgacggcg gtaaaaaaga agatattttc aaaatgggtg cttcggcaat
     2701 tgccaacaat gtttccgctc atttcggact tgagggcatt accgcaaaca tcgtcaacgc
     2761 ttgtgcggca ggcacaatga gcatcggcta tgcctgtgac cttatccgtg agggcaaggg
     2821 tgatgtgttc atcgcaggcg gttcggacag cttttcttca cttgcattca gcggtttcca
     2881 cgctctccat gcgcttgacg aaaacgcctg ttccccgttc aatcacagca caggtatcac
     2941 gctcggcgag ggttcgggta ttcttgtaat cgaaagctac gaacacgctg ttgaacgagg
     3001 cgcaaagatt tactgtgaaa ttctcggttc gggtgtaagc agtgacgctt accacattac
     3061 cgctccccgt cccgacggtg aaggtcagat gagtgcaatc agaagggctg ttgaaagctc
     3121 tgctctgact tttgacgata tcgactacat aaacgcacac ggaacgggta ctgccaaaaa
     3181 tgacgaggct gaatttcttt cacttcacac actttttgac ggcaacgacc acctttctgt
     3241 cagctcaaca aaatctatga caggtcattg cctcggtgcg gctggttcaa ttgaggctgt
     3301 attttccgta aaagcaataa aagaaaacct cgttccgcct acaatcggct actccgatga
     3361 agatttgaag gtgctttccg aaaaggctgg caacattgac tttattccga acaagagcca
     3421 cacaaaagat gttcactatg caatgtcaaa ctcatttgca ttcggcggca acaacgcaag
     3481 catcattttc tcggacaacg agcatgatat tcccgacaac agtagaaatg aaaaaattta
     3541 cattacgggc atttcaaagc ttacaggcac aaagactgac gaacacagcc ttaactgcaa
     3601 tcttacctcc gaggattatg acaaacacgg aatcaaggtt gcattttaca gaaagcttga
     3661 ccgtttcagc cagctccagc ttttgagcgg tatggacgca cttgcagacg ctgacattaa
     3721 aattgacaaa gacaacgaat ataaaacagg tattgtaatc ggcacggctg acggccctat
     3781 gaccgaaatt gttgatttcc agaaaaaggc aatcacaaga ggtaccgaaa agggcagtgc
     3841 tttttcattc ccaaatacgg tttacaatgc cgcaggcggt tatctgagca ttttctcagg
     3901 catcaagggc tacaacgcaa ctgttgcaaa cggcaatcag gcaggactgc agagtatttg
     3961 ctatgccgct gatattcttg cagacggcaa cgaaagtgtt atgctcgccg caggtactga
     4021 tgaaaacaca aaaacaaacc ttgaactcta tacaaaggcc gaattgcttg aaaaaccgct
     4081 cggtgagggc tctgtaactc tcgttcttga aacagaagaa agtgcaaacg gcagaaatgc
     4141 acgcaagtat gcagaaatta agggctatgc acaggctcac cgccctgtat cgtatgacaa
     4201 ctcagaggtt gacagcaagg ctgttgttga ggttatcgaa aaggcttgtg tggatgccgg
     4261 cattgaggca gacaatatcg actttgtatg ctgtgacgac aggaagatta tcaagacgct
     4321 tatgccatgc tatgatgtat cgcaggaaat cggcaatgca agagccgcag caagcgcaat
     4381 gacagcggca tatgcggctg agctcctttc tgacagcgag aaaaattacg aatacggact
     4441 tgctctttca atgggtgcgg gcggaacata ctctgccgta attctgaaga aagcgtaaaa
     4501 atcggaggta aatatgagca aaaccgctct tgtaacaggt tcatcaaggg gcattggcaa
     4561 ggcttgcgct ttaaagcttg cagagcttgg gtatgacatt gccgtgaact gcaattcaaa
     4621 tttagaaatg gctcaaaagg ctgttgacga aattacatca ctcggcagaa aagccgttgc
     4681 ctacaaggcg aacacggcag atattgacga agtaaaggat atgttccgca gtattcagca
     4741 ggactttggc ggaattgatg tgcttgtcaa caacgcaggt gtggttgacg acgcttacct
     4801 tttgatgatt aaagacgagt cgcttgaaag aagtcttgac attaatatca aaggatattt
     4861 taattgtgca agacaggcat cgcttaaaat gctccgcaaa aagagcggaa tcatcatcaa
     4921 catttcttcc gtaagctctg ttcttgcagt tgaaggtcag tcggtttaca gtgcaacaaa
     4981 gggtgcggta aacgctatga cacacacgct tgcaaaagaa cttgcaaagt acggaatcag
     5041 agtaaacgca gttgcacccg gttttatcga aaccgaaatg atgaacggca ttcccgaaga
     5101 gttgcagaaa aagtatcttg aggctattcc cgaaaagaga ttcggcacag ttcaggatgt
     5161 cgcaaatgta gtcggacagc tttgcagtga cgatttttca tatatgacag gtcaggtgct
     5221 tgtgcttgac ggaggactca gcttatgatg aatctgcttg aaatcaatca aagaataaaa
     5281 caaagaccac cctttcagat gattgagagg gtgaccgagc ttgagccgaa tgtttcggca
     5341 acaggtataa aaaatgtgtc ggtgaacgag ccgtattttg caggtcattt tcccgacaca
     5401 ccgattatgc cgggagtatt gctcattgaa tctgcggcac agctttgcag tcttgtattt
     5461 gctcccgaaa gcgttgagga ggacaagtta tatgttcttc taaaagtcaa ggatttcaaa
     5521 atgctccgcc ccgttattcc gggtgatacg cttattatca gcgtaaatgt tacaatgtca
     5581 acaaagtcgg catttgaatt tgcgtgtgtc atcaaggttg acggtgaagt gagggcaaag
     5641 ggaagtcttt tgtttaccac aatggataaa aatgcggttt acaagccgtc acaggagtga
     5701 ttatgaaggt tctcgtatta aacggtagtc caaagggcga aaaaagcaat actctcaata
     5761 ttacaaaagc atttcttgac ggcttttcgg ctgacactga gattgaatat atcacggtta
     5821 aaaaggaaac aatcaagccg tgtatgggtt gcttttcgtg ttggagcaga acacccggcg
     5881 aatgtgttat aaaggacgat atgcagaaaa tctacgaaaa gattaattct gccgatatta
     5941 tcattgagag ctttccgctc tactttttcg gtatgccgtc acagatgaaa gcattaaccg
     6001 acagatgtct gccgtatatg ctcccctatt cgggaaatgt tgccgaggac aaagaagcct
     6061 ctttccatga actgcgtgat gaagcaatgc acgaaaagag gcttttggtt attacaactt
     6121 gcggctatgt gagtgccgaa ccgatgtatc ccgcacttac aaaacagctt gatttgattt
     6181 gcggtaacgg caattacacg atgataaaat gtcccgaggg cgagcttttt attgcagaaa
     6241 aagctgaaag gcagagaaaa gcataccttg attcaatcac ggaggcaggc agggaattct
     6301 gcgaaaaccg ctgtctttgc gatgaaacaa tgaaaaaaat ttcaaagcct attctctccc
     6361 ccaaaggatt cgaggcaatt actaaggctc attggaaaat gagttaatca gcttttcggg
     6421 cggaacatat tcggacaatg ctccgagaac aaactcgttg acagcgtctg caagtttttc
     6481 ggaactctct gcacagccgt cattgaacca acggacataa accgagatga atcccgaaac
     6541 gacaaactca acaaggtatt tgagtttagt ttcattttta aaattaagca caggtcttat
     6601 tgaaacctcg ataaatcttt tcaaaagctc aacagagcga cccgagccga acacctcggg
     6661 agaatttttc agaattttat taatctgttc tttattttca acaatggaaa gaccgataaa
     6721 attcagctga tttacaaggt tgttgccgtc acggtcggat tttttcgcat ggctgataac
     6781 atcattgatt atatcgtaat tgatatcatc gacaacatcc tgaaccgtgt gataatggcg
     6841 gtaaaaggtt ttgcggttaa tcatcgcctt ttctgcaagc tcagtcaccg tgattttgga
     6901 aacatttttt tcggcaagca aatcaatcag cgaatttttt atattggttc ttgtttttac
     6961 aatgcgaagg tcagtaacat tagcgtccat actatcaccc cataaaacag tttgattata
     7021 gcaccaaaat ttttttgagt caacggaggt ccttatgaca ggtctgataa ttgaaggcgg
     7081 agcaaggcga ggaattttta ccgccggtat aaccgactgt ctgcttgaaa acaaaataca
     7141 ctttgactat gttgcaggag tttcggcggg agctgaggtc gcccttgatt ttaccgcaaa
     7201 acaggaaggt cgttcccgca gggttattat gccccacaga acaggtgatt tttcggttct
     7261 cggttttctt tcaatggatc ttgacaatat gatttacaga tttccttatc aggactatcc
     7321 gttcgatttt gatacatttt ttgcgtcaga tacaaactgc gaatttgtgg caaccgactg
     7381 cgtaacaggc aaggcaaaat atttttccga gaacaaaagc gaacagcgat tgcttgactc
     7441 agtaagagcg tcctgcacag ttcctattct ctatcagata agcgaatttg agggcggaaa
     7501 gtatgttgac ggcagtgttg ccgacgctgt tccctttgac cgtgcgtttg aacagggctg
     7561 ttcccgtgtg cttgtgcttt tgacaaagcc cgaaaatgag ccttgcacgg actatcgcaa
     7621 atttgaattt ttaatcaaca aaaaatacaa ggactatccg aacctcatca acgctcttat
     7681 gacgagattt gaccgctata atgagcaatg caaaagaatg aaacagcttg aggaggacgg
     7741 catacttatg gtactccgcc cgtcacacaa gtatgtaaaa tcatttgaga tgaacacgga
     7801 tgtgcttgac gaggcgtata acgccggcaa aaatcttgcc aaagaaaagc ttgccgaaat
     7861 tgaagatttc ctcaatgttc tcgaaaagaa ataatcaaaa caacaagtta cattaatata
     7921 tcttcccaaa aagcaaggtg caatttcgtg ccttgctttc tttttatgtg caatttcaac
     7981 aagtaaaaag tgttcaatat gtgacttatt ccaattaaat aacaatagta ttgtataatg
     8041 tcaaaaaata tggtatattc agcatatatt ttaaaacacg gagatttata tgaaaaaaca
     8101 actaatgatt tttgactttg tgtgtcttgg aatcggagca atttttttga cttttgtcgc
     8161 catacttcaa aattgcggta taaacattac caatggaagt gtaatcggaa ttgtcataac
     8221 agtgcttttg tttattctga tattactttg ctgatgtgtg ataaagaagt agtagaagtg
     8281 taaaaaattt tgccgttcct atccggcgtt tgcgcattgc gccggatagg tcgggcggtc
     8341 attcgggcag gtctaccttg ccaacgaaag agtaataaat atcaa
//
