LOCUS       c00070_gnlPro..        16449 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OKBNLKHF_70.
ACCESSION   c00070_gnlPro..
VERSION     c00070_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 01:15:10
            Original ID  :: gnl|Prokka|OKBNLKHF_70
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16449
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16449
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3456:6449]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3457..6449
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16449
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16449
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             295..654
                     /locus_tag="ctg70_1"
                     /transl_table=11
                     /translation="VLSRNDFIIVAIGEHGSPLHYGNHFASYIKFVPIYNMCHYLRASD
                     ERPYRQTTTFIYKNSWEDDVLHFANRLPDIHFTFSILHFQFKISVRASLFLLLRNYLLK
                     LTATCLLHRYRNRYA"
     CDS             complement(622..1809)
                     /locus_tag="ctg70_2"
                     /transl_table=11
                     /translation="MKKKIFILLLCVVLIATCILCGVTGIFGNDSHNSPKPQTPDTAVT
                     ENVTFPSTVDSLTLKVGESKLIELSSEKAKSVTKWTSSDSKIVTVDDGGRVDALKEGTA
                     LISAVLKDKSKSEFQVTVAKSTAKKQQSYSTCITANLDKLENNKRNMAKNLYAIKVNRT
                     ANCVTVYTYDEKGKYTIPVRAMICSTGLDNSTITGDYTIGIKSEWLFLVGDVFGRYISG
                     ISGDYLFHSVPYYSMSEEDLELEEFNKLGEQASQGCVRLAVSDAKWVYDNCPTGTNVSI
                     YDDAENAGPLGKPDAIKITDFTNKWDPTDSNKKCPYAKATPTISGANDYTIKSGGEFYA
                     LAGVTAVDTCGNDITSKIEVFGNVVTTRKGKYKVTYSVTDVLKRTSSVTITVTVQ"
     CDS             1974..2510
                     /locus_tag="ctg70_3"
                     /transl_table=11
                     /translation="MVIIMAHPIKHFRTITRHRHKVIANCARAGILRQGLIHDLSKYSP
                     TEFIPGAKYYQGTRSPNEKERELYGYSQAWLHHKGRNRHHYEYWNDYNPKTKQIENVEM
                     PVKYVIEMFCDRVAASKIYNGKNYTDGAPFTYFCRIRGKHRMHPNTEALLEKLLVMLRD
                     EGEEKTFAYIRSMKK"
     CDS             2699..3190
                     /locus_tag="ctg70_4"
                     /transl_table=11
                     /translation="MKTDRVITAMIEYFGSDKKRIHHFLKVYSFAKTIGESENLLPDDQ
                     ELLEISAIVHDIGIKVSEEKYNSSAGKYQELEGPHEAEKLLAALGYEKTFIDKVCYLVG
                     HHHTYGNIDTLPYRILVEADFLVNLYEDDSSRSAAEQAYDKIFRTNTGKNLLKIMFLIP
                     "
     CDS             3457..5694
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg70_5"
                     /sec_met_domain="Gly_radical (E-value: 2.7e-41, bitscore:
                     131.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 7.8e-272, bitscore:
                     893.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEWTNFAGGKWESDIDVRDFIQRNYTPYDGDQSFLEGPTEATD
                     KLWGELKELQKEERAKGGVLDMETEVVSGITAYGAAYLDKDLEKVVGLQTDKPLKRAFM
                     PYGGIKMAEQSCQMYGYTPSPKLHEIFTKYHKTHNQGVFDIYTPEMKLARHNKILTGLP
                     DTYGRGRIVGDYRRVALYGIDRLIEGKKEDFAETNRQGMRRGDFQLREEIADQIRALND
                     MKEMALSYGFDISQPAKNAAEAVQWLYFGYLAAIKTQNGAAMSVGRVSTFLDIYIERDL
                     ENGTLTESQAQELVDHFVMKCRMVKFARIESYNQLFSGDPVWATLEVAGLGIDGRSMVT
                     KNDYRFLHTLENMGPSPEPNLTVLYSSRLPENFKKYAAHISVTTSSIQYENDDVMRPVW
                     GDDYSICCCVSATQTGKEIQFFGARANLAKCLLYAINGGIDEKTKMQVGPEYTPITSEY
                     LDYDEVIKKYDTMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTDVRRTFATGIAG
                     FSHVVDSLSAIKYAKVKVIRDEDGIAVDFETEGDFPRYGNNDERADKIAVDLLKTFMAK
                     LKYCHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQNGLLA
                     SLNSVAKLPYEYALDGISNTQTINPGALGHNDDERVDNLVNVMDGYFDQGAHHLNVNVF
                     GTEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             5694..6449
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 76.2;
                     E-value: 1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg70_6"
                     /sec_met_domain="Radical_SAM (E-value: 1.9e-30, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNAVKGFVHSIETFGSVDGPGVRFVIFLSGCAMRCQFCHNPDT
                     WKHDENTVEYTADELLNKALAYRPYWKNKGGITVSGGEPLLQIDFLLDLFKKAKKQGVN
                     TCIDTSANPFTTKEPFYSKWKELMEYTDLLLLDIKHIDNEQHKILTGQPNTNILEMARQ
                     LSDMGKPVWIRHVLVPERNDKDEYLFRLADFIHSLKNVERVEVLPYHTLGVYKWKALGY
                     DYPLEGIEPPTKERVRNAEMILNGEKTRD"
     CDS             6798..8651
                     /locus_tag="ctg70_7"
                     /transl_table=11
                     /translation="MKSENIKKFGCVLLSAIMLSGISVCAVSAEEKSTEIHIVHTNDIH
                     GYYKSTSGGQIGFEAVKTIADKENADLILDAGDTFHGQSFATVEEGKSIAELMDAVGYD
                     AMTPGNHDWSYSADRLRELDRENSFTILASNVADTNGNRYFDNNFYIKNVTADDGTKVR
                     VGVFGVIDEDFYTSTSAKNVENVRFENSAETATAYANFLRDDENCDIILALTHNATPEK
                     FIAETSGIDAVIAGHQHILIDKYCTDSDGKSVKLVEANCFFKNVGVLTLTYSNEKGVTD
                     AVEKTYSSADTQGMSDEKIASDISAIEKREQSVLSEVIGESSREYAYSWEELRTSEQEI
                     GRIVTAAYLDFTGADVAMENAGGIRSGIPKGNVTYSDLISISPYGNVLVEKELTGQQII
                     DILEFSVDLMKKNNAVYDLQKQAIKDGEDPYQYSWPDNSGSVMQFSGLSAVYDYSKPYG
                     GRVSDVKIGGKAIDTLKTYRVVSNNYAFDSSDYGDVASLTTVKEYTTCEQILRDYIGKG
                     DFEKAAANANLVEKSSPSEEPTATQEQTVQTAPTGESATVGTTSVNPTSATGGAATSDS
                     TPSQPDKNGGVQTGVTATAVMMLVVISGGVLFALAERKKRI"
     CDS             8784..9002
                     /locus_tag="ctg70_8"
                     /transl_table=11
                     /translation="MDKNKKLFYTIIGAISALAAATAAFLALKKHRCAEQKLIEEIDDI
                     VSEKEPEEAAKEEPQAEVTADELAEEE"
     CDS             complement(9223..10374)
                     /locus_tag="ctg70_9"
                     /transl_table=11
                     /translation="METLIIGKPKIEKLDNRARLCSKISENGKSSYTLWFDVDAKYADY
                     LTESADAFVVALLPYAMNNSLNISAEAKMSKQLCFQLNEIFIPVLTKNSKLFNKISISA
                     KELTQENYCCKNASATGFSRGVDSFDTICSLSENNTEKLSHLTFFNVGSHRSTANYTPE
                     QSAELYANRLEIAKKSAKIFDMPLIDINSNLGEHLTLPYVKVHHYCSFSAVLCMQKFFK
                     NYYYASGYPISSFSIKQCDTGSAHYEAFTASMLSTESTDFYITGLEKTRLEKVDFISKF
                     PITYDNLNVCYYGENNCGHCEKCVRTQFELMALGKLELYKNVFDIPKFYRDKNKYMDYV
                     LKHQNKDYYAEILSLMKKKGFKLTPIQKIKKVVYAVYLKFRGN"
     CDS             complement(10390..11574)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg70_10"
                     /sec_met_domain="UDPG_MGDP_dh_N (E-value: 2.5e-37,
                     bitscore: 119.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="UDPG_MGDP_dh (E-value: 4.5e-29, bitscore:
                     91.4, seeds: 679, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAIAGTGYVGLSNAVLLSQKHEVTAVDVVESKVRLINEKKSPI
                     ADREIEEYLADKKLNLVATVDAKSAYKNADFVIISTPTNYDDERHFFDTSSVEAVIELV
                     IECNPNAVIVIKSTIPVGYTKSVIEKYKYTKILFSPEFLREGKALYDNLYPSRIIVGVD
                     MANEELKKSAETFATALADCAIKENIDTLFMDYTEAEAVKLFANTYLAMRVSFFNELDT
                     YAEMKNLNTKSIIDGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLKANFSDVPNDIISA
                     VVTSNKTRKEFITSQIMNKNPKTVGIYRLTMKSNSDNFRQSSIQSVMELLKNNGIELII
                     YEPTLKVDLFEGFGVENDFEKFVTKSDVIVANRYSSVLDCVKEKVYTRDLFFRD"
     CDS             complement(11589..13352)
                     /locus_tag="ctg70_11"
                     /transl_table=11
                     /translation="MYSTIKSVQLLTALLKKYNINKLVLSPGGSDIPIIHSLENDDFFE
                     CHSVVDERSAVYYGIGLAQQTKSPVACICTSGTAVSNYLPGMTEAFYQDVPIVAITADK
                     DPYRLNQLMLQKTQQVNIFESVTKKSVNLPVVRGGNDRWYCERLINEALSELDHHGTGP
                     VHINIPIVENSAVYDCENLPQVRKINRISPDMPSEEWREYAERLSKYKKILVIAGQNNC
                     FSEDDRACVEKFFEKYNCLISVEHMSNLKCKGCLMTYPLSECSMQGMFGELCPDLIISF
                     GNNIASYKLKPMIKAHKEKFVHWQIDTAGRIRDFSDKLTDVFECTPQYFFNCFAENAPQ
                     DSKNDMTYYNMWNDDIKMLDYSSNLPFSNMYVAKKLAEIIPDRSVLHLAILSSTRTMQF
                     FNLKPNVKVYSNIGALGIDGCMSSFFGQASATDELAFCVVGDLSFFYDMNSAGIRGIKN
                     NARIILLNNGGGSEFHFFMGKEKIPTINQYICAEHHKGAKGWIESLGYDYYSATTKEEV
                     DNIIPTLAEESDRPIFVEIFTDMEEDAKLINRLFHDNRMKFGGMKLKMMEKAKSILSPS
                     QIQKAKKLLKK"
     CDS             complement(13368..13526)
                     /locus_tag="ctg70_12"
                     /transl_table=11
                     /translation="MSLKNTLKKVRQGIIKTFKAKNVVPVYVQKENNNILNGKTALITG
                     GSGIIKN"
     CDS             complement(13528..14607)
                     /locus_tag="ctg70_13"
                     /transl_table=11
                     /translation="MKKVGIVTFHRALNYGAVLQSYALQKTVSSLGAECEIVDYICPKI
                     TADYKPFRIYKNDLLKSFAKSCVMVRRRAKRRDAFKSFFNNYLVKSKKSYTPQNIGELK
                     NDYDLFISGSDQVWSPRCVGFDPAYFLTFADDKQKYSYAASFAVPTLPDEFIDEYKKRL
                     NGFQKFSVREPSGEKLVKELTGRTAETHLDPTLLISADEWKKIAVSKIDKPYILIFTAN
                     PAVSLVDFALKLSKEKNLPVYCINDAPHPVSHGINYIVAPTVEEFVGCFKNAEYVVTNS
                     FHGTAFSVIFNKNLFVEFKNKSGRNIRSEGLLKSLGIDREIVDGNCRETEINWYDVNEK
                     IKNQTIISLDYLKSFVSGD"
     CDS             complement(14607..15521)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg70_14"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.5e-30,
                     bitscore: 97.0, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEYTFSVFTPSYNRAKTLPRLYEALKRQTYRNFEWIIVDDGSAD
                     NTKETVEKFISDRPDFNITYKYQTNKGKHIATNVAAQIAKGEFFITIDSDDSVKDNALE
                     TFINEWNKIPDKDRSKYKGISCRTCNESGKTNGCPLPSERFDCSDLDLRLKYKIDGEMW
                     GMTKLEIIRANPYPCVSGLHFYPENIYWDNIGRKYITRFIDTPLRYYINDQENSLTGNA
                     YSAHRETIFVRLHFINECWDYAKSNPKFFIKQFVGLSRDGLLNGKRFSEIKKMPDTFSK
                     RALAIIFYPMGYFLYKKQSGGSR"
ORIGIN
        1 gattttgttt agatgaaagt ttatcagtag gggcgttcat tggacgcccg cctggatgaa
       61 attttatggt taacaaatat tttttgatgt aatgaaagct atgtatcgtc tgtaggggcg
      121 gatattatca gccagtaagt aatggcagaa cagttttgtt atatacaatt tttataaata
      181 ttacaattca gtagcggcga accgtgttcg ccaatcggtt tgtttgcaaa aacaaatcga
      241 acatatacac agtttttatt atataaaaat gatatgttaa taaacaaata atttgtgctg
      301 agtcgcaacg attttataat cgttgcgatt ggcgaacacg gttcgccgct acattatggc
      361 aatcattttg cgtcatatat aaagtttgtt ccaatatata atatgtgcca ttacttgcgg
      421 gcgtccgatg aacgccccta cagacaaaca acaactttca tatataaaaa cagttgggaa
      481 gacgatgttt tgcattttgc aaaccgtctt cccgacattc attttacatt ttcaatttta
      541 cattttcaat ttaaaatctc cgttcgtgca tctttatttt tgcttttgcg gaactatctt
      601 cttaaattga ctgcaacgtg tttattgcac cgttaccgta atcgttacgc ttgatgttct
      661 tttaagcaca tcggtgactg aatatgttac cttgtacttg ccttttcggg tggttaccac
      721 attgccgaaa acttcgattt tcgatgttat gtcgttgcca caggtgtcaa cggctgttac
      781 tccggcaagg gcataaaatt cgcctccgct tttgattgtg taatcgtttg caccgctgat
      841 tgtcggtgtt gctttggcat acggacattt tttattgctg tctgtcggat cccatttgtt
      901 ggtaaaatcg gtaattttga ttgcatccgg ttttccgaga gggcctgcat tttctgcgtc
      961 gtcatatatg cttacattcg tgcctgtggg gcagttgtca taaacccact ttgcatccga
     1021 aactgcaagc cttacgcaac cctgtgacgc ctgttcgcca agcttgttga actcctcaag
     1081 ctccaaatct tcttcgctca ttgagtagta gggaacggag tggaaaagat aatcgcccga
     1141 aattccgctg atgtatcttc cgaaaacatc gcccacaagg aaaagccatt cggacttgat
     1201 tccgattgtg tagtcacccg tgattgtcga attgtcaaga cctgtggagc aaatcatcgc
     1261 ccttacgggg atcgtgtact tgcctttttc gtcatatgtg taaaccgtca cgcagtttgc
     1321 cgtgcggttg accttgattg cgtacagatt ttttgccatg ttacgcttgt tgttttcaag
     1381 cttgtcaaga tttgccgtta tacaggttga gtagctttgc tgttttttcg cagttgattt
     1441 tgccaccgta acctgaaatt ccgacttcga tttgtctttt aaaacggcag aaatcagagc
     1501 tgtaccttct ttgagagcgt caacccttcc gccgtcatca acggtaacaa ttttactgtc
     1561 cgagcttgtc catttggtaa cggattttgc tttttcggat gacagttcaa taagctttga
     1621 ttcgccgacc tttaatgtga gcgaatcgac cgtgctcgga aatgtcacat tttcggttac
     1681 tgccgtatcg ggcgtctgcg gttttggaga attatgagaa tcatttccga aaattcccgt
     1741 cacaccgcat aatatgcagg ttgcaatgag gacaacacaa agtaaaagaa tgaaaatttt
     1801 ctttttcata gattacctat ccttatagaa tttaacatta aatggttaca aaattttaac
     1861 ctttgtatat tataactttt tttcgacaat cttgcaagtg ctattttaaa tcggcgagaa
     1921 atgtggtaaa atgtcagtcg gagaatgttt tgtattttcc aaactaacaa tttatggtga
     1981 taattatggc acacccgatt aaacatttca gaacaataac ccgtcacagg cacaaggtaa
     2041 ttgccaactg tgcaagggcg ggaattctca gacagggatt aatacacgat ttgtcaaagt
     2101 attcgcctac agaatttatt ccgggtgcaa agtattacca gggcacgaga agtcccaatg
     2161 aaaaggaaag agagctgtat ggctattcac aggcgtggct gcatcacaag ggcagaaacc
     2221 gtcaccatta cgaatactgg aacgattaca acccaaagac aaagcagatt gaaaatgttg
     2281 aaatgcccgt aaaatatgtt atcgaaatgt tctgcgaccg agttgccgca agcaaaatct
     2341 acaacggcaa aaattacacg gacggcgctc cgtttacata tttttgcaga atcagaggca
     2401 aacaccgtat gcacccaaac accgaggctt tgcttgaaaa attattggtt atgctgagag
     2461 atgagggtga agaaaagacc tttgcatata taagaagtat gaaaaagtga ttggtgcgaa
     2521 tcctcccgtc tgaaatatag tcacaatgcg ttgcacataa atgtactgcc tttttgctcg
     2581 ttatttcaga cagcgctttg ctccctttat ccgccactgg cggtggttgc aaggcttgca
     2641 caaacaaaaa actatctaca cgaatagggt acggcggctc gccgtaagga gtgataatat
     2701 gaaaaccgac agggttataa ctgctatgat tgaatatttt ggaagtgaca agaaaaggat
     2761 tcaccatttt ctcaaggttt attcattcgc aaagacaatc ggtgaaagtg aaaatctttt
     2821 gcccgacgat caggagcttc ttgaaatctc cgcaatcgtt cacgacatcg gcataaaggt
     2881 gagcgaagaa aagtacaatt catctgcagg aaagtatcag gagcttgaag gtcctcacga
     2941 ggctgaaaag ttgcttgccg ctctcggcta cgaaaaaaca tttattgaca aagtttgtta
     3001 ccttgtggga caccatcaca cctatggaaa tattgatact ttgccgtacc gaattttggt
     3061 agaggcagac ttccttgtga acctttatga ggacgattca agccgcagtg cagcagagca
     3121 ggcgtatgac aaaatattcc gcacaaatac aggaaaaaat ctgctgaaaa taatgttcct
     3181 cataccctaa aattgtactc atttaccata gcgttttgag tgtgaaaaag tggtgtaaaa
     3241 agtatctcaa aatgcttgac aacgccctta aaaagtgtta ttttaatggt gttggttata
     3301 tgattataaa agtgaataaa tgacagaata caaggatgta tgacgatttt ttcaaggagc
     3361 tgaccttacc gggcgtctgc ttggaattga gtcggcattt ttttgtgtca tatacaaaat
     3421 tcagtattaa ttatcattat cggaggtttt acagtaatga gagaagaatg gacaaatttt
     3481 gcaggtggca aatgggagtc cgacattgat gtcagagact tcattcagag aaactacaca
     3541 ccttatgacg gtgaccagtc tttccttgaa ggtcctacag aagctacaga caagctctgg
     3601 ggcgagctca aggaactcca gaaggaagaa agagccaagg gcggcgttct tgatatggaa
     3661 actgaggttg taagcggcat cacagcttac ggcgctgcat atcttgataa agaccttgaa
     3721 aaggttgtag gtcttcagac agacaagcct ctcaagcgtg catttatgcc ttatggcggt
     3781 atcaaaatgg ctgagcagtc atgccagatg tatggctaca ctccaagccc taaactccac
     3841 gaaatcttta caaaatatca caagactcac aaccagggtg tattcgatat ctatactccc
     3901 gagatgaagc ttgcccgtca caacaagatt cttacaggtc ttcccgacac atacggcaga
     3961 ggcagaatcg tcggtgacta cagaagagtt gctctttacg gtattgaccg tcttatcgaa
     4021 ggcaagaaag aggactttgc agaaacaaac cgtcagggta tgagaagagg cgacttccag
     4081 cttcgtgaag aaatcgctga tcagattcgt gctcttaacg atatgaagga aatggcactt
     4141 tcttacggct ttgatatttc acagcctgct aagaacgctg cagaggcagt tcagtggctc
     4201 tacttcggtt atcttgctgc tatcaagact cagaacggcg ctgcaatgag cgttggtcgt
     4261 gtatcaacat tcctcgacat ctacattgag cgtgaccttg agaacggtac acttacagaa
     4321 tcacaggctc aggaactcgt tgaccacttt gttatgaagt gccgtatggt taagtttgca
     4381 agaattgagt cttacaacca gctcttctcg ggcgaccctg tatgggctac actcgaagtt
     4441 gcaggtcttg gcattgacgg ccgttcaatg gttacaaaga acgactaccg tttcctccac
     4501 acacttgaga atatgggacc ttcacctgag ccaaacctca cagttcttta ttcttcaaga
     4561 cttccggaga acttcaagaa gtatgctgct catatttcag ttacaacaag ctcaattcag
     4621 tacgagaacg atgatgtaat gcgtcctgta tggggcgatg attactcaat ctgctgctgc
     4681 gtatccgcaa cacagacagg taaggaaatc cagttcttcg gtgcaagagc taaccttgct
     4741 aagtgccttc tctacgctat caacggcggt attgatgaaa agacaaagat gcaggttggt
     4801 cctgaatata cacctatcac atcagagtac cttgattatg acgaagttat caagaagtat
     4861 gacacaatga tggattggct tgctcacctc tatgtaggca cacttaacat gattcactac
     4921 atgcatgata agtactacta tgaggcagca gaaatggctc ttatcgatac agatgtaaga
     4981 agaacatttg caacaggtat tgcaggcttc tcacatgttg ttgactcact cagcgctatt
     5041 aagtacgcta aggttaaggt tatccgtgac gaggacggca ttgctgttga ctttgaaaca
     5101 gagggcgact tcccaagata cggtaacaat gacgagagag cagataagat tgccgttgat
     5161 cttctcaaga catttatggc taagctcaag tattgccaca catacagaga ttcagagcct
     5221 acaacttcta tccttacaat cacatcaaat gttgtttacg gtaaggctac aggttcactt
     5281 cctgacggca gaaaagccgg cgagccgctt tcacctggtg ctaacccaag ctacggtgca
     5341 gagcagaacg gccttcttgc ttcacttaac tctgttgcta agcttcctta tgagtacgct
     5401 cttgacggta tttcaaatac tcagacaatc aacccgggtg ctctcggaca caacgatgac
     5461 gagcgtgttg acaacctcgt aaatgttatg gacggctact ttgatcaggg cgcacaccac
     5521 ctcaatgtaa atgtattcgg tacagaaaaa ctcattgacg ctatggagca tcctgagaag
     5581 gaagagtacg ctaacttcac aatccgtgta tcgggttatg ctgttaagtt catcgacctt
     5641 acaagagagc agcagctgga tgttattgcc agaacctgcc acgacagaat gtaatgtcgg
     5701 acaacgctgt taaaggcttt gtacactcaa tagaaacttt tggctctgtt gacggtccgg
     5761 gtgtgagatt tgtgattttt ctgagcggtt gcgcaatgcg ttgccagttc tgccacaatc
     5821 ccgacacatg gaaacacgat gaaaacaccg tggagtacac cgccgacgag ttgcttaata
     5881 aagcgcttgc ataccgcccc tattggaaaa ataagggcgg tatcacagta agcggaggtg
     5941 agccgctttt acagattgac tttttgcttg atttgttcaa gaaggctaaa aagcagggcg
     6001 ttaatacctg tattgacaca agcgccaacc cgtttacaac caaagagccg ttctattcaa
     6061 agtggaaaga gctaatggaa tatacggatt tgctgttgct tgatataaag catatcgaca
     6121 acgaacagca caaaatcctt acaggacagc caaacaccaa tattcttgaa atggcaagac
     6181 agctttccga tatgggcaag cccgtatgga taagacatgt tcttgtgcct gaaagaaatg
     6241 ataaggacga gtatcttttc agacttgccg actttattca ctcactcaag aatgttgagc
     6301 gtgtcgaggt tcttccgtat cacacactcg gtgtgtacaa gtggaaggct ctcggttatg
     6361 actatcctct cgagggcatt gagcccccga caaaagagcg tgttaggaat gcggaaatga
     6421 ttcttaacgg cgaaaaaaca agagattaat ttcttatata acaacggcag caccgatttt
     6481 tttggtactg ccgtttttgt tttgattttt atttgttatt ctgcttttgt tgttttttct
     6541 tcagcaaaat tgatgaatca aaggtgtatt caaagatttt taggctgtcc ctgttgagaa
     6601 atctcagcgt aacttttggg ttatcaacat cttaaaataa tagcagataa agcagaattt
     6661 tgcattaata aaacaacttc cgccgtattc aatataaaac tattgaaaaa ttgcgcaaaa
     6721 tatggtacaa ttcacccaac aaagcattga ttttacaaac aattactaca tatttctaat
     6781 ttgaaaggag taaagtaatg aaatcagaaa acataaaaaa attcggttgt gttttgctta
     6841 gtgccataat gctttcgggc atttcggtgt gtgctgtatc tgccgaagaa aaatcaacgg
     6901 aaattcatat cgttcacaca aacgatattc acggctacta caagtccaca tcgggcggtc
     6961 aaatcggttt tgaggcagtc aagaccattg cggacaagga aaatgccgat ttgatacttg
     7021 atgcaggcga cacctttcac ggacagtcat ttgccaccgt tgaagaggga aaaagcattg
     7081 ccgagcttat ggacgctgta ggttatgacg caatgacacc cggcaatcac gattggtcat
     7141 acagtgccga caggctgaga gagcttgaca gagaaaactc ttttaccata cttgcctcaa
     7201 atgtggcaga cacaaacggc aacagatatt ttgacaacaa cttttatata aagaatgtta
     7261 ctgctgatga cggcacaaag gtaagagtcg gagttttcgg cgttattgac gaagattttt
     7321 acacatcaac atcggcaaaa aatgttgaaa atgttcgctt tgaaaattca gccgaaacag
     7381 cgacagcgta cgcgaatttt ctcagagatg acgagaattg tgatattata cttgcgctga
     7441 ctcataatgc aacccccgaa aaattcattg ccgaaacatc gggcattgat gcggtaatcg
     7501 caggtcatca gcacattctc attgacaaat actgtactga cagtgacggc aagagcgtaa
     7561 agcttgttga ggcaaactgc tttttcaaaa atgtaggtgt gcttactctg acatattcca
     7621 atgaaaaggg cgttaccgat gcagtcgaaa aaacatattc gtctgccgat actcagggaa
     7681 tgtccgatga aaagattgcg tccgatattt ctgcaattga aaagcgtgaa cagagcgtac
     7741 tcagcgaagt aatcggcgag agcagtaggg agtacgctta cagctgggaa gagctgagaa
     7801 caagcgagca ggagataggc agaatcgtaa cagccgctta tcttgacttt acgggtgctg
     7861 atgttgcaat ggagaatgca ggcggaatcc gttcgggtat tccaaagggt aatgtgacat
     7921 attccgattt gatttcaatt tcaccctacg gcaatgtgct tgttgaaaag gagcttacag
     7981 gtcagcagat tattgatatt cttgaatttt cagttgacct tatgaagaaa aacaatgcgg
     8041 tttatgacct tcaaaagcag gcgataaagg atggggaaga cccgtatcag tacagctggc
     8101 cggataacag cggttcggta atgcagttca gcggtttaag tgcggtatat gactattcaa
     8161 agccgtacgg cggcagagtg tcagatgtaa aaatcggagg aaaggcaatt gacactttaa
     8221 aaacttacag agtggtttca aataactatg cgtttgacag ttccgattac ggcgatgttg
     8281 cgtcgctcac gaccgtgaaa gaatatacca cctgcgaaca aattctgcgt gattatatcg
     8341 gcaagggcga ttttgaaaaa gctgccgcaa atgcaaatct tgttgagaaa tcgtcaccgt
     8401 cggaagaacc gactgctact caggaacaga ctgttcagac tgctccgacg ggtgagtctg
     8461 caactgtcgg tacaacctct gtaaatccga cttcggcaac aggcggtgcc gcaacatcgg
     8521 acagcactcc ttcacagcct gataaaaacg gcggtgttca gacaggagtg acagcaacgg
     8581 ctgttatgat gcttgttgta atttcgggcg gagtgctttt tgcccttgca gagcgtaaaa
     8641 agagaatata acacactgac agccatttgt gcaaagatta tcagttgcct attgaaaaat
     8701 ttgtaaaaat gatataaaat agcaataagt agaaaaatac ggtttttccg ctgatttata
     8761 ttaatactga aagaggtgcc ggaatggata aaaacaaaaa attattctac acaatcatcg
     8821 gtgcaatctc tgcacttgcg gctgccacag cagcatttct cgctttaaaa aagcacagat
     8881 gcgcagaaca gaagcttatt gaggaaattg acgatattgt ttccgaaaaa gagcctgagg
     8941 aggctgcaaa ggaagaaccg caggcagaag ttacagccga tgagcttgct gaggaagaat
     9001 aagcaacaag ttgttgcacc caattcgagt agcagtattt gcatgtgcaa aagttaaata
     9061 cccgagcggt gctttcaatt aagaattgaa agttgaaaac agataatgat gtcggcagtg
     9121 tgacatcgca ggctattcaa gaaaacagtt taaaaaagaa aatgcatcag atgcccgaaa
     9181 aggtctgatg catttttgtt ttgtgagaag taaccgtaag ccttaatttc ctctgaattt
     9241 aagataaacg gcatagacaa cctttttaat tttttgaatt ggcgtaagct tgaaaccctt
     9301 ctttttcata agactgagaa tttctgcata atagtccttg ttctgatgtt ttagaacata
     9361 gtccatatat ttgttcttgt ctctgtaaaa tttcggaata tcaaaaacat tcttatacag
     9421 ttcaagtttt ccgagtgcca taagctcaaa ttgcgttctg acgcactttt cacagtgacc
     9481 gcagttgttc tcaccgtagt aacacacatt gaggttatca tatgtaatcg gaaattttga
     9541 aatgaagtca accttttcaa gccttgtctt ttcaagacct gtaatgtaaa aatctgtact
     9601 ttcggtactc agcatacttg ccgtaaatgc ctcatagtgc gccgagccgg tgtcgcattg
     9661 ttttatcgaa aaactgctta tcgggtatcc tgaagcatag taatagtttt tgaaaaattt
     9721 ctgcatacac aagactgccg aaaagctgca ataatgatga acctttacat acggcagggt
     9781 aaggtgttca ccgagatttg aattgatgtc aatcaacggc atatcaaaga tttttgcgga
     9841 tttttttgca atttcaagac gatttgcgta cagctcggca gactgttcgg gtgtgtaatt
     9901 tgccgtactt ctgtgggagc cgacattgaa aaaggtaaga tgactcagct tttccgtgtt
     9961 gttttcggaa agactgcaaa ttgtgtcaaa tgaatccaca cctctcgaaa atcctgttgc
    10021 agatgcattt ttgcagcagt agttttcctg tgtaagctct tttgcagata tcgaaatttt
    10081 gttgaataat tttgaatttt ttgtaagaac gggaatgaaa atttcattaa gctgaaaaca
    10141 cagttgcttc gacatctttg cttctgccga aatattcaga ctgttgttca ttgcatacgg
    10201 caacagcgca acaacgaatg cgtcggcact ttcggtcaga tagtcagcat actttgcatc
    10261 aacatcaaac cagagagtgt aggaagactt tccgttttcg ctgatttttg aacagagtct
    10321 ggcacgatta tcaagttttt caattttcgg tttgccgata atcaatgttt ccatactttt
    10381 accctcaaat taatctctga aaaacaaatc tcttgtgtaa accttttctt ttacacagtc
    10441 aagaacggag ctgtatctgt ttgcaacgat tacatccgat tttgtgacga acttttcaaa
    10501 gtcgttttca acaccaaagc cctcgaataa atcgacttta agtgtcggtt cgtagataat
    10561 taactcgatg ccgttatttt tcaaaagctc cataacgctc tgaattgagc tttgtctgaa
    10621 gttatcggaa tttgacttca ttgtaaggcg gtaaattccg acagtttttg gatttttatt
    10681 cataatctgc gatgtaataa attcttttct tgtcttgtta gatgttacaa cagcgctgat
    10741 tatgtcattc ggaacatccg aaaagttcgc cttgagctgt tttgtgtcct ttggcagaca
    10801 gtaaccgccg tagccaaagg acggattgtt gtagtgattt ccgattctcg gatcaagaca
    10861 tacaccgtca atgatacttt tagtgttaag gttcttcatt tcggcatatg tgtcaagctc
    10921 gttgaaaaag ctgacacgca ttgcaaggta tgtatttgca aaaagcttta ccgcctctgc
    10981 ctcggtgtag tccataaaga gagtgtctat gttttcctta attgcacagt ctgcaagtgc
    11041 cgttgcaaaa gtctcggcag attttttcag ttcttcattt gccatatcaa caccgacaat
    11101 gattcttgac ggatagaggt tatcatagag agccttgccc tcacgcaaaa attcgggact
    11161 gaaaagaatt tttgtgtatt tgtatttttc aataacactt tttgtgtatc caaccggtat
    11221 agtggatttg ataactataa ccgcatttgg gttgcattca attacaagct caattacagc
    11281 ctcaacggac gatgtatcaa aaaagtgtct ttcgtcatcg taattggtag gagtagagat
    11341 aattacaaaa tcagcgtttt tgtacgcaga ttttgcatca acggttgcaa ccaaatttaa
    11401 ttttttgtca gcaagatatt cttcgatttc cctgtcggca atcggagatt tcttttcatt
    11461 gattaacctt accttgcttt caactacatc aacagcggtt acctcgtgtt tctgcgaaag
    11521 aagtacagcg tttgaaagac ctacatagcc tgtcccggca attgctattt tcatttggtt
    11581 tcacctgatt acttttttaa taattttttt gccttttgaa tctgtgacgg actgagaatt
    11641 gactttgctt tttccatcat cttgagcttc attccgccaa atttcattct gttgtcatga
    11701 aaaagcctgt taataagctt tgcgtcctct tccatatcgg tgaaaatctc aacaaaaatc
    11761 ggtcggtcgg attcttctgc aagtgtagga ataatgttgt caacttcttc cttggttgtt
    11821 gcgctgtaat agtcatatcc gagtgattca atccagccct ttgcgccctt gtgatgttcg
    11881 gcacagatgt actgattgat tgtaggaatc ttttccttgc ccataaagaa gtgaaattct
    11941 gaaccgccgc cgttgttgag aagaataatt ctcgcattgt tcttgattcc tctgatgcct
    12001 gcggagttca tatcatagaa gaaactgagg tcgcccacaa cgcaaaaggc aagctcgtct
    12061 gttgccgatg cctgtccgaa gaacgaagac atacagccgt caatacccag agcgccgata
    12121 ttgctgtaaa ccttgacatt cggtttcaaa ttgaagaact gcatagttct tgtactgctg
    12181 agaattgcaa ggtgcagaac agaacggtcg ggaataattt cagcaagctt tttggcaaca
    12241 tacatatttg agaacggaag attgcttgaa taatcaagca ttttaatatc gtcattccac
    12301 atattgtagt atgtcatatc attttttgaa tcctgtggtg cgttctctgc aaagcagtta
    12361 aagaaatact gcggtgtaca ttcaaaaaca tctgtcagct tgtcggaaaa atctctgatt
    12421 cttcccgcag tatcaatctg ccagtgaaca aatttttcct tgtgagcctt aatcataggc
    12481 ttgagtttat atgaagcaat attgttgccg aacgaaataa taagatcggg gcataactcg
    12541 ccgaacattc cctgcattga gcattctgac aaaggatagg tcataaggca acccttgcac
    12601 ttgaggtttg acatatgctc aaccgatata aggcaattgt atttttcaaa gaacttctca
    12661 acgcacgctc tgtcatcttc tgagaagcag ttgttctgac cggcaatgac aagaattttc
    12721 ttatattttg aaagcctttc tgcatattca cgccactcct cggagggcat atcgggagaa
    12781 attctgttga ttttcctaac ctgaggaaga ttttcacaat catatacagc cgagttttca
    12841 acaatcggaa tattgatatg cacaggtcct gttccgtgat ggtcaagctc cgaaagagcc
    12901 tcgttaataa gtctttcgca gtaccatctg tcatttccgc cgcgcacaac gggaagatta
    12961 acggattttt ttgtaaccga ttcaaaaata ttgacctgct gggttttctg cagcataagc
    13021 tgatttaatc tgtacgggtc tttgtcagcg gtaattgcga caatagggac atcctgataa
    13081 aatgcctctg tcatacccgg aagatagttg cttacggctg tacccgaggt gcagatacag
    13141 gcaacggggg attttgtctg ttgtgcaagt ccgatgccgt aatacacggc acttctctcg
    13201 tcaacgaccg aatgacactc aaaaaaatcg tcattttcaa gtgaatgaat tataggaata
    13261 tcactgcctc cgggagaaag caccaatttg ttgatattat attttttcag aagtgcagtg
    13321 agcaactgaa cgctttttat tgtagaatac atacgctttc ctccgcttta gtttttgata
    13381 attccggaac cgcctgtaat cagagcggtt ttgccgttaa gaatattgtt gttctccttc
    13441 tgcacataca cgggaacaac attttttgct ttaaatgttt tgattatgcc ctgtctgact
    13501 ttttttagtg tatttttaag actcatttta atcaccgctg acaaaggatt taagataatc
    13561 caaagatatt attgtctggt ttttgatttt ttcgttcaca tcgtaccagt ttatttcggt
    13621 ttctcggcag tttccgtcaa caatttcacg gtcgattcca agacttttca aaagaccttc
    13681 ggagcggatg tttcttccgc ttttgttctt gaattcaaca aaaagattct tgttgaaaat
    13741 aacagaaaac gctgttccgt gaaacgagtt tgtaacaaca tattcggcat ttttgaaaca
    13801 gccgacaaat tcctcaacag taggtgcaac aatataattt ataccgtgac ttacagggtg
    13861 aggtgcatcg tttatgcagt aaacgggaag gttcttttct tttgacagtt taagggcaaa
    13921 atccacaagc gaaactgccg gattagccgt aaaaatgagg atatacggtt tgtcgatttt
    13981 tgaaacagca atctttttcc attcgtctgc cgaaatcagc agggtaggat caagatgagt
    14041 ttcggcggtt ctgcccgtga gttcttttac aagcttttca ccgctcggtt cacggacgga
    14101 gaacttctga aaaccgttca gtcttttttt atattcatca ataaattcat cgggcaatgt
    14161 cggaacggca aagcttgccg catatgaata cttctgtttg tcatcggcaa atgtcagaaa
    14221 ataagcggga tcaaaaccga cgcatctcgg actccacacc tgatcgcttc ccgaaatgaa
    14281 caagtcataa tcgtttttaa gctctccgat attctgcgga gtatacgact ttttactctt
    14341 tacaagatag ttattgaaaa acgacttaaa agcgtctctg cgttttgctc ttcttcttac
    14401 catgacacag ctttttgcaa aggatttcag aaggtcgttt ttataaatgc gaaagggttt
    14461 gtagtcggct gtgattttcg gacagatata gtcaacaatt tcacactctg caccgagcga
    14521 ggaaacggtt ttttgcaacg catagctctg aagcacagcg ccgtagttca atgcacggtg
    14581 aaatgttaca atgcctacct ttttcattat ctgcttcccc ctgattgttt tttgtacaaa
    14641 aaatatccca tgggataaaa tatgattgca agagccctct ttgaaaatgt gtcgggcatc
    14701 ttttttattt cggaaaatct tttaccgttg agcaagccgt cacgggaaag tcccacaaat
    14761 tgtttgataa agaacttagg attgctcttt gcgtaatccc aacattcgtt tataaagtgg
    14821 agtcttacga aaatagtttc cctgtgagcc gagtaagcgt tacccgtcaa agaattttcc
    14881 tgatcgttta tgtaatatcg caacggtgtg tcaataaaac gggttatata ctttcttccg
    14941 atattgtccc aatagatatt ttcgggataa aaatgaagtc ccgaaacaca cggatagggg
    15001 ttggctctga ttatttcaag ttttgtcatt ccccacatct caccgtcaat tttatacttc
    15061 aatctcaggt caaggtcgga acagtcaaat cgttctgacg gcagaggaca accgtttgtt
    15121 ttgccgcttt cgttacaggt gcggcatgaa attcccttgt attttgacct gtctttatcg
    15181 ggaattttgt tccattcgtt tataaatgtt tcaagggcgt tgtcttttac gctgtcatcg
    15241 gagtcaatcg ttataaagaa ttcacccttt gcaatctgtg ccgcaacatt tgttgcaatg
    15301 tgttttcctt tgttggtctg atatttatag gttatgttaa agtcgggtct gtcgctgatg
    15361 aatttctcaa ccgtttcttt tgtgttgtcg gctgaaccgt catcaacaat tatccattca
    15421 aaatttctgt atgtctgtct tttcagcgcc tcatataatc tgggcagagt ttttgccctg
    15481 ttatatgacg gtgtaaaaac ggaaaaagta tattcagtca ttgcaacctc aaaatgataa
    15541 taatttagct tttcttaaac ttcttcttaa ttttatcctt gataagaacg agttcttttc
    15601 ttgagaaaat gagcggaacg gaaacggcat atcctgccag tccgcttgct gcacagagaa
    15661 gaaggaatga tatccagctg tttgcgtgta caaagctgtt gataaagatg aacatggtga
    15721 taacaacagc aaagcagaac catcctctga aaatagacct gtaatatgtt gtaagcttta
    15781 ttttcaaaat atgtgcggcg tacaacggaa cgaatactat cgctttaaga ccgataaaaa
    15841 cagagctgac gcctgcaata gcataaacgc cgagcggtgt aaagtgtatg agcagtaaaa
    15901 cgataataac cgtaagaaca ccgcatacaa gcgagataag aacggaggcc ttgagcttgt
    15961 tgcatacggt gaaaaggcta gaaagagttc ttgtgtgaca ggtaaacagg tatgaaatac
    16021 atacaagcac cgacaaaatc tgaattatgg taatttcgtc cggagatttg gtcggctgcc
    16081 acaatgtata gaacttgttg ccaaacgcaa taaatcccgc aagaggtgca gtcatgagaa
    16141 aactcataat ctttgacgaa aactttgttt cttcaacaag taagtccgtg ttgccctttg
    16201 cataaaggat tgtaaatctg ggagtgaaga tatttgcaat ggttgtaata aagttatcaa
    16261 tgcagtgcgg aacggtgttt gcaatcgata aaagtcccat gagtcccgct ccgagagtca
    16321 ggttacagat taacaggtca agacctctgt taagagctgt gctgagataa ccgattgacg
    16381 accaaattcc tgcggaaatc agaactttta ccagcttgaa actgaaaagg ttgaagttca
    16441 tctttactt
//
