LOCUS       c00068_gnlPro..        16233 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HFJIEPDP_68.
ACCESSION   c00068_gnlPro..
VERSION     c00068_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:43:44
            Original ID  :: gnl|Prokka|HFJIEPDP_68
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16233
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16233
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3240:6233]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3241..6233
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16233
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16233
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             3..95
                     /locus_tag="ctg68_1"
                     /transl_table=11
                     /translation="LCTVVYYVTTLHTSAARLDEIFCLIIYVLM"
     CDS             complement(476..1663)
                     /locus_tag="ctg68_2"
                     /transl_table=11
                     /translation="MKKKIFILLLCVVLIATCILCGVTGIFGNDSQNSPKPQTHDTAVT
                     ENMTFPSKVDSLTLKVGESKLIELSSEKAKSVTKWTSSDSKIVTVDDGGRVDALKEGTA
                     LISAISKDKSKSEFQVTVAKSTTKKQQSYSTCITANLDKLENNKRNTAKNLYAIKVNRT
                     ANCVTVYTYDEKGKYTIPVRAMICSTGLDNSTITGDYTIGIKSEWLSLVGDVFGRYISG
                     ISGDYLFHSVPYYSMSEEDLELEEFNKLGEQASQGCVRLAVSDAKWVYDNCPTGTNVSI
                     YDDAENAGPLGKPDAIKITDFTNKWDPTDSNKKCPYAKATPIISGANDYTIKSGGEFYA
                     LAGVTAVDTCGNDITSNIEVFGNVVTTRKGKYKVTYSVTDVLKRTSSVTITVTVQ"
     CDS             1828..2364
                     /locus_tag="ctg68_3"
                     /transl_table=11
                     /translation="MVIIMAHPIKHFRTITRHRHKVIANCARAGILRQGLIHDLSKYSP
                     TEFIPGAKYFQGTRSPNEKERELYGYSQAWLHHKGRNRHHYEYWNDYNPKTKQIENVEM
                     PVKYVIEMFCDRVAASKIYNGKNYTDGAPFTYFCRIRGKHRMHPNTEALLEKLLVMLRD
                     EGEEKTFAYIRSMKK"
     CDS             complement(2303..2548)
                     /locus_tag="ctg68_4"
                     /transl_table=11
                     /translation="VNSFLVTSKIFNHSSYNPVGFHIITPYGEPPYPIRVDRFLFVQFC
                     RGSIATIFQTGGFAQTITFSYFLYMQMSFLHPHLSA"
     CDS             complement(2567..2797)
                     /locus_tag="ctg68_5"
                     /transl_table=11
                     /translation="VSHKVTNFVNKCFFVAESSKQLFSLVRTFKFLILSCRRIVLFFAH
                     LYADVVNDCGDFKKLLIVGQKIFTFTDCLCE"
     CDS             3241..5478
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_6"
                     /sec_met_domain="Gly_radical (E-value: 3.6e-41, bitscore:
                     131.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.8e-271, bitscore:
                     892.9, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEWTNFAGGKWESDIDVRDFIQRNYTPYDGDQSFLEGPTEATD
                     KLWGELKELQKEERAKGGVLDMETEVVSGITAYGAAYLDKDLEKVVGLQTDKPLKRAFM
                     PYGGIKMAEQSCQMYGYTPSPKLHEIFTKYHKTHNQGVFDIYTPEMKLARHNKILTGLP
                     DTYGRGRIVGDYRRVALYGIDRLIEGKKEDFAETNRQGMRRGDFQLREEIADQIRALND
                     MKEMALSYGFDISQPAKNAAEAVQWLYFGYLAAIKTQNGAAMSVGRVSTFLDIYIERDL
                     ENGTLTESQAQELVDHFVMKCRMVKFARIESYNQLFSGDPVWATLEVAGLGIDGRSMVT
                     KNDYRFLHTLENMGPSPEPNLTVLYSSRLPENFKKYAAHISVTTSSIQYENDDVMRPVW
                     GDDYSICCCVSATQTGKEIQFFGARANLAKCLLYAINGGIDEKTKMQVGPEYTPITSEY
                     LDYDEVIKKYDTMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTDVRRTFATGIAG
                     FSHVVDSLSAIKYAKVKVIRDEDGVAVDFETEGDFPRYGNNDERADKIAVDLLKTFMAK
                     LKYCHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQNGLLA
                     SLNSVAKLPYEYALDGISNTQTINPGALGHNDDERVDNLVNVMDGYFDQGAHHLNVNVF
                     GTEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             5478..6233
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 76.2;
                     E-value: 1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_7"
                     /sec_met_domain="Radical_SAM (E-value: 2.5e-30, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNAVKGFVHSIETFGSVDGPGVRFVIFLSGCAMRCQFCHNPDT
                     WKHDENTVEYTADELLNKALAYRPYWKNKGGITVSGGEPLLQIDFLLDLFKKAKKQGVN
                     TCIDTSANPFTTKEPFYSKWKELMEYTDLLLLDIKHIDNEQHKILTGQPNTNILEMARQ
                     LSDMGKPVWIRHVLVPERNDKDEYLFRLADFIRSLKNVERVEVLPYHTLGVYKWKALGY
                     DYPLEGIEPPTKERVKNAEMILNGEKTRD"
     CDS             6778..6996
                     /locus_tag="ctg68_8"
                     /transl_table=11
                     /translation="MDKNKKLFYTIIGAISALAAATAAFLALKKHRCAEQKLIEEIDDI
                     VSEKEPEEAAKEEPLAEVTADELAEEE"
     CDS             complement(7217..8368)
                     /locus_tag="ctg68_9"
                     /transl_table=11
                     /translation="METLIIGKPKIEKLDNRARLCSKISENGKPSYTLWFDVDTKYADY
                     LTESADAFVVALLPYAMNNSLNISAEAKMSKQLCFQLNEIFIPVLTKNSKLFNKISISA
                     KELTQENYCCKNASATGFSRGVDSFDTICSLSENRTEKLSHLTFFNVGSHRSTANYTPE
                     QSAELYENRLEIAKKSAKIFDMPLIDINSNLGEHLTLPYVKVHHYCSFSAVLCMQKFFK
                     NYYYASGYPISSFSIKQCDTGSAHYEAFTASMLSTESTDFYITGLEKTRLEKVDFISKF
                     PITYDNLNVCYYGENNCGHCEKCVRTQFELMLLGKLELYKNVFDIPKFYRDKNKYMDYV
                     LKHQNKDYYAEILSLMKKKGFKLTPIQKIKKAVYAIYLKFREN"
     CDS             complement(8384..9568)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_10"
                     /sec_met_domain="UDPG_MGDP_dh_N (E-value: 2e-37, bitscore:
                     119.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="UDPG_MGDP_dh (E-value: 5.9e-29, bitscore:
                     91.4, seeds: 679, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAIAGTGYVGLSNAVLLSQKHEVTAVDVVESKVKLINEKKSPI
                     ADREIEEYLADKKLNLVATVDAKSAYKNADFVIISTPTNYDDERHFFDTSSVEAVIKLV
                     IECNPNAVIVIKSTIPVGYTKSVIEKYKYTKILFSPEFLREGKALYDNLYPSRIIVGVD
                     MANEELKKSAETFATALADCAIKENIDTLFMDYTEAEAVKLFANTYLAMRVSFFNELDT
                     YAEMKNLNTKSIIDGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLKANFSDVPNDIISA
                     VVTSNKTRKEFITSQIMNKNPKAVGIYRLTMKSNSDNFRQSSIQSVMELLKNNGIELII
                     YEPTLKVDLFEGFGVENDFEKFVTKSDVIVANRYSSVLDCVKEKVYTRDLFFRD"
     CDS             complement(9583..11346)
                     /locus_tag="ctg68_11"
                     /transl_table=11
                     /translation="MYSTIKSIQLLTALLKKYNINKLVLSPGGSDIPIIHSLENDDFFE
                     CHSVVDERSAVYYGIGLAQQTKSPVACICTSGTAVSNYLPGMTEAFYQDVPIVAITADK
                     DPYRLNQLMLQKTQQVNIFESVTKKSVNLPVVRGGNDRWYCERLINEALSELDHHGTGP
                     VHINIPIVENSAVYDCENLPQVRKINRISPDMPSEKWREYAERLSKYKKILVIAGQNNC
                     FSEDDRACVEKFFEKYNCLISVEHMSNLKCKGCLMTYPLSECSMQGMFGELCPDLIISF
                     GNNIASYKLKPMIKAHKEKFVHWQIDTAGRIRDFSDKLTDVFECTPQYFFNCFAENAPQ
                     NSKNDMTYYNMWNDDIKMLDYSSNLPFSNMYVAKKLAEIIPDRSVLHLAILSSTRTMQF
                     FDLKPNVKVYSNIGALGIDGCMSSFFGQASATDELAFCVVGDLSFFYDMNSAGIRGIKN
                     NARIILLNNGGGSEFHFFMGKEKIPTINQYICAEHHKGAKGWIESLGYDYYSATTKEEV
                     DNIIPTLAEESDRPIFVEIFTDMEEDAKLINRLFHDNRMKFGGMKLKMMEKAKSILSPS
                     QIQKAKKLLKK"
     CDS             complement(11522..12601)
                     /locus_tag="ctg68_12"
                     /transl_table=11
                     /translation="MKKVGIVTFHRALNYGAVLQSYALQKTVSSLGAECEIVDYICPKI
                     TADYKPFRIYKNDLLKSFAKSCVMVRRRAKRRDAFKSFFNNYLVKSKKSYTPQNIRELK
                     NDYDLFISGSDQVWSPRCVGFDPAYFLTFADDKQKYSYAASFAVPTLPDEFIDEYKKRL
                     NGFQKFSVREPSGEKLVKELTGRTAETHLDPTLLISADEWKKIAVSKIDKPYILIFTAN
                     PAVSLVDFAIKLSKEKNLPVYCINDAPHPVSHGINYIVAPTVEEFVGCFKNAEYVVTNS
                     FHGTAFSVIFNKNLFVEFKNKSGRNIRSEGLLKSLGINREIVDGNCRETEINWYDVNEK
                     IKNQTIISLDYLKSFVSGG"
     CDS             complement(12601..13515)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_13"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-30,
                     bitscore: 97.8, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEYTFSVFTPSYNRAKTLPRLYEALKKQTYRNFEWIIVDDGSAD
                     NTKETVEKFISDRPDFNITYKYQTNKGKHIATNVAAQIAKGEFFITIDSDDSVKDDALE
                     TFINEWNKIPDEDRSKYKGISCRTCNESGKTNGCPLPSERFDCSDLDLRLKYKIDGEMW
                     GMTKLEIIRANPYPCVSGLHFYPENIYWDNIGRKYITRFIDTPLRYYINDQENSLTGNA
                     YSAHRETIFVRLHFINECWDYAKSNPKFFIKQFVGLSRDGLLNGKRFSEIKKMPDTFSK
                     RALAVIFYPMGYFLYKKQSGGSR"
     CDS             complement(13539..15083)
                     /locus_tag="ctg68_14"
                     /transl_table=11
                     /translation="MKKLSTSKQMAINMVAAIVSFLIGTGINFVLAPYLVKELGSETYG
                     FIGLANNFVQYATIVTSALNSMSGRFISIEYSKGNIDKASRYFSSVLVADLIIAGVLLL
                     VSSIITFNIEFILNVPENLVDSVKILFALTFATFIISVITAIFTTAAFVKNKLYINSLR
                     DIASNTLKLLLVVILFSFFPAKVYFLAMASLASGIFLLLTNIKVKNKILPEVKMNFNLF
                     SFKLVKVLISAGIWSSIGYLSTALNRGLDLLICNLTLGAGLMGLLSIANTVPHCIDNLI
                     TTIANIFTPRFTILYAKDNTDLLVEETKFSSKIMSFLMTAPLAGFIAFGNKFYTLWQPT
                     KSPDEITIIQILSVLVCISYLFTCHTRTLSSLFTVCNKLKASVLISLVCGVLTVIIVLL
                     LIHFTPLGVYAIAGVSSVFIGLKAIVFVPLYAAHILKIKLTTYYRSIFRGWFCFAVVIT
                     MFIFINSFVHANSWMSFLLLCAASGLAGYAVSVPLIFSRKELVLIKDKIKKKFKKS"
     CDS             complement(15107..15931)
                     /locus_tag="ctg68_15"
                     /transl_table=11
                     /translation="MVYKIMYPPIPNMGDLLNKDMLEELFNIKVVRKDLKSCNLIAIGS
                     ALDHIMYSTYPRIRAKQKIEHFMNDNVHIWSTGFIRGNAELDLGLMFRHIHIHALRGRL
                     SLQRMENILGKKLDVPTGDGGLLAERWLGFYPEKKYRVGIIPHFKEQDHPVVKKLLDNY
                     ENSTLIDLKENPKKVVEKIGECEYIISSSLHGMIVADSFHIPNMHITLTNNMFGDGNKY
                     NDYLSAFDITHTPFDCSNGDMPTISEVKNNYRIDPDVVELKKEQLFNAFPKF"
ORIGIN
        1 gtctttgcac tgttgtatac tatgttacta cactgcacac atcggccgcc cgccttgatg
       61 aaatattttg tttaatcata tatgttttga tgtgattata attgtgtatt gaaccttgca
      121 cgcattgcgt gcaatcgtat gcgttgcata cgaacgggcg aacacggttc cccctaaaac
      181 atacattgca aaaataattg gaatgttata cttggtcaaa atatgtatgt tgctgtgtgg
      241 ttgatttggc tttgcaacca aatcaaatgg cggtcactga ccgccgctac tgtatgtaca
      301 aacaattgct atgttatgct cgggcaacat ttgtaattta ctattaaaac cgtctgcacg
      361 aacacacgaa cataaaaaat gcggtggcac attgccaacc gcatttttat tttacatttt
      421 caattttcca ctttcaattt aaaagctccg ctcggagaac agtggcgcac catgtttatt
      481 gcaccgttac cgtaatcgtt acgcttgatg ttcttttaag cacatcggtg actgaatatg
      541 ttaccttgta cttgcctttt cgggtggtta ctacattgcc gaaaacttcg atattcgatg
      601 ttatgtcgtt gccgcaggtg tcaacggctg ttactcctgc aagggcgtaa aattcgccgc
      661 cgcttttgat tgtgtaatcg tttgcaccgc tgattattgg tgttgctttg gcatacgggc
      721 attttttatt gctgtctgtc ggatcccatt tgttggtaaa atcggtgatt ttgattgcat
      781 ccggttttcc gagagggcct gcattttctg cgtcgtcata tatgcttaca tttgtgcctg
      841 tggggcagtt gtcataaacc cactttgcat ccgaaaccgc aagtcttacg catccttgtg
      901 acgcctgttc gccaagcttg ttgaactcct caagctccaa atcttcttcg ctcattgagt
      961 agtagggaac ggagtggaaa agataatcgc cagaaattcc gctgatgtat cttccgaaaa
     1021 catcgcccac aagggaaagc cattcggact tgattccgat tgtgtagtca cccgtgattg
     1081 tcgaattgtc aagacctgtg gagcaaatca tcgcccttac ggggattgtg tacttgccct
     1141 tttcgtcata tgtgtaaacc gtcacgcagt ttgccgtgcg gttgaccttg attgcgtaca
     1201 ggttttttgc cgtgttacgc ttattgtttt caagcttgtc aagatttgcc gttatacagg
     1261 ttgagtagct ttgctgtttt ttcgtggttg attttgccac cgtaacctga aattccgact
     1321 ttgatttgtc ttttgaaatg gcagaaatca gagccgtacc ctctttgaga gcgtcaaccc
     1381 ttccgccgtc atcaacggta acaattttac tgtccgagct tgtccatttg gtaacggatt
     1441 ttgctttttc ggatgacagt tcaataagct ttgattcgcc tacttttaat gtgagcgaat
     1501 cgaccttgct cggaaatgtc atattttcgg ttactgccgt atcgtgcgtc tgcggttttg
     1561 gagaattttg agaatcattt ccgaaaattc ccgtcacacc gcataatatg caggttgcaa
     1621 tgaggacaac acaaagtaaa agaatgaaaa ttttcttttt catagattac ctatccttat
     1681 agaatttaac attaaatggt tacaaaattt taacctttgt atattataac tttttttcga
     1741 caatcttgca agtgctattt taaatcggtg agaaatgtgg taaaatgtca gtcggagaat
     1801 gttttgtatt ttccaaacta acaatttatg gtgataatta tggcacatcc gattaaacat
     1861 ttcagaacaa taacccgtca caggcacaag gtaattgcca actgtgcaag ggcaggaatt
     1921 ctcagacagg gattaataca cgatttgtca aagtattcgc ctacagaatt tattccgggt
     1981 gcaaagtatt ttcagggcac gagaagtccc aatgaaaagg aaagagagct gtacggctat
     2041 tcacaggcgt ggctgcatca caagggcaga aaccgtcacc attacgaata ctggaacgat
     2101 tacaacccaa agacaaagca gattgaaaat gttgaaatgc ctgtaaaata tgttatcgaa
     2161 atgttctgcg accgagttgc cgcaagcaaa atctacaacg gcaaaaatta cacggacggc
     2221 gctccgttta catatttctg cagaatcaga ggcaaacacc gtatgcaccc caacaccgag
     2281 gccttgcttg aaaaattatt ggttatgctg agagatgagg gtgaagaaaa gacatttgca
     2341 tatataagaa gtatgaaaaa gtgattgttt gtgcgaatcc gcccgtctga aatatagtcg
     2401 caatgctacc cctacagaat tgcacaaaca aaaaacggtc tacacgaata gggtacggcg
     2461 gctcgccgta aggagtgata atatgaaaac cgacagggtt ataactgcta tgattgaata
     2521 ttttggaagt gacaagaaaa gaattcacca ttttctcaag gtttattcat tcgcaaagac
     2581 aatcggtgaa agtgaaaatc ttttgcccga cgatcaggag cttcttgaaa tctccgcaat
     2641 cgttcacgac atcggcataa aggtgagcga agaaaagtac aattcgtctg caggaaagta
     2701 tcaggaactt gaaggtcctc acgaggctga aaagttgctt gctgctctcg gctacgaaaa
     2761 aacatttatt gacaaagttt gttaccttgt gggacaccat cacacctatg gaaatattga
     2821 tactttgccg taccgaattt tggtagaggc agacttcctt gtgaaccttt acgaggacga
     2881 ttcaagccgc agtgcagcag agcaggcata tgacaaaata ttccgcacaa atacgggaaa
     2941 aaatctgctg aaaataatgt tcctcatacc ctaaaattgt actcatttac catagtgctt
     3001 tgagtgtgaa aaagtggtgt aaaaagtatc tcaaaatgct tgacaacgcc cttaaaaagt
     3061 gttattttaa tggtgttggt tatatgatta taaaagtgaa taaatgacag aatacaagga
     3121 tgtatgacga ttttttcaag gagctgacct taccgggcgt ctgcttggaa ttgagtcggc
     3181 atttttttgt gtcatataca aaattcagta ttaattatca ttatcggagg ttttacagta
     3241 atgagagaag aatggacaaa ttttgcaggt ggcaaatggg agtccgacat tgatgtcaga
     3301 gacttcattc agagaaacta cacaccttat gacggcgacc agtctttcct tgaaggtcct
     3361 acagaagcta cagacaagct ctggggcgag ctcaaggaac tccagaagga agaaagagcc
     3421 aagggcggcg ttcttgatat ggaaactgag gttgtaagcg gcatcacagc ttacggcgct
     3481 gcatatcttg ataaagacct tgaaaaggtt gtaggtcttc agacagacaa gcctctcaag
     3541 cgtgcattta tgccttacgg cggtatcaaa atggctgagc agtcatgcca gatgtatggc
     3601 tacactccaa gccctaaact ccacgaaatc tttacaaaat atcacaagac tcacaaccag
     3661 ggtgtgttcg atatctacac tcccgagatg aagcttgccc gtcacaacaa gattcttaca
     3721 ggtcttcccg acacatacgg cagaggcaga atcgtcggtg actacagaag agttgctctt
     3781 tacggtattg accgtcttat cgaaggcaag aaagaggact ttgcagaaac aaaccgtcag
     3841 ggtatgagaa gaggcgactt ccagcttcgt gaagaaatcg ctgatcagat tcgtgctctt
     3901 aacgatatga aggaaatggc actttcttac ggctttgata tttcacagcc tgctaagaac
     3961 gctgcagagg cagttcagtg gctctacttc ggctatcttg ctgctatcaa gactcagaac
     4021 ggcgctgcaa tgagcgttgg tcgtgtatca acattcctcg acatctacat cgagcgtgac
     4081 cttgagaacg gtacacttac agaatcacag gctcaggaac tcgttgacca ctttgttatg
     4141 aagtgccgta tggttaagtt tgcaagaatt gagtcttaca accagctctt ctcgggcgac
     4201 cctgtatggg ctacactcga agttgcaggt cttggcattg acggccgttc tatggttaca
     4261 aagaacgact accgtttcct ccacacactt gagaatatgg gaccttcacc tgagccaaac
     4321 ctcacagttc tttattcttc aagacttccc gagaacttca agaagtatgc tgctcatatt
     4381 tcagttacaa caagctcaat tcagtacgag aacgatgatg taatgcgtcc tgtatggggc
     4441 gatgattact caatctgctg ctgcgtatcc gcaacacaga caggtaagga aatccagttc
     4501 ttcggcgcaa gagctaacct tgctaagtgc cttctctacg ctatcaacgg cggtattgat
     4561 gaaaagacaa agatgcaggt tggtcctgaa tatacaccta tcacatcaga gtaccttgat
     4621 tatgacgaag ttatcaagaa gtatgacaca atgatggatt ggcttgctca cctctatgta
     4681 ggcacactta acatgattca ctacatgcat gataagtact actatgaggc agcagaaatg
     4741 gctcttatcg atacagatgt aagaagaaca tttgcaacag gtattgcagg cttctcacat
     4801 gttgttgact cactcagcgc tattaagtac gctaaggtta aggttatccg tgacgaggac
     4861 ggcgttgctg ttgactttga aacagagggt gacttcccaa gatacggtaa caatgacgag
     4921 agagcagata agattgccgt tgatcttctc aagacattca tggctaagct caagtattgc
     4981 cacacataca gagattcaga gcctacaact tctatcctta caatcacatc aaatgttgtt
     5041 tacggtaagg ctacaggttc acttcctgac ggcagaaaag caggcgaacc actttcacct
     5101 ggtgctaacc caagctacgg tgcagagcag aacggtcttc ttgcttcact taactctgtt
     5161 gctaagcttc cttacgagta cgctcttgac ggtatttcaa atactcagac aatcaacccg
     5221 ggtgctctcg gacacaacga tgacgagcgt gttgacaacc tcgtaaatgt tatggacggc
     5281 tactttgatc agggcgcaca ccacctcaat gtaaatgtat tcggtacaga aaaactcatt
     5341 gacgctatgg agcatcctga gaaggaagag tatgctaact tcacaatccg tgtatcgggt
     5401 tatgctgtta agttcatcga ccttacaaga gagcagcagc tggatgttat tgccagaacc
     5461 tgccacgaca gaatgtgatg tcggacaacg ctgttaaagg ctttgtacac tcaatagaaa
     5521 cttttggctc tgttgacggt ccgggtgtga gatttgtgat ttttctgagc ggttgcgcaa
     5581 tgcgttgcca gttctgccac aatcccgaca cctggaaaca cgatgaaaac accgtggaat
     5641 ataccgccga cgagttgctt aataaagcgc ttgcataccg cccctattgg aaaaataagg
     5701 gcggtatcac agtaagcgga ggtgagccgc ttttacagat tgactttttg cttgatttgt
     5761 tcaagaaggc taaaaagcag ggcgttaata cctgtattga cacaagcgcc aacccgttta
     5821 caaccaaaga gccgttctat tcaaagtgga aagagctaat ggaatatacg gatttgctgt
     5881 tgcttgatat aaagcatatc gacaacgaac agcacaaaat ccttacagga cagccaaaca
     5941 ccaatattct tgaaatggca agacagcttt ccgatatggg caagcccgta tggataagac
     6001 atgttcttgt gcctgaaaga aatgataagg acgagtatct tttcagactt gccgacttta
     6061 tccgttcgct caagaatgtt gagcgtgtag aggtgcttcc gtatcacaca ctcggtgtgt
     6121 acaagtggaa ggctctcggt tatgactatc ctctcgaggg cattgagccc ccgacaaaag
     6181 agcgtgttaa gaatgcggaa atgattctta acggcgaaaa aacaagagat taatttctta
     6241 tataacaacg gcagtaccga ttttttggta ctgccgtttt tgttttgatt tttatttgtt
     6301 attctgcttt tgttgttttt tcttcagcaa aattgatgaa tcaaaggtgt attcaaagat
     6361 ttttaagccg tccttgttga gaaatcgtca ccgtcggaag aatcgaccgc tactcaggaa
     6421 cagactgttc agactgctcc gacgggtgag cctgcaactg tcggtacaac ctccgtaaat
     6481 ccgacttcgg caacaggcgg tgccgcaaca tcggacagta ctccttcaca gcctgataaa
     6541 aacggcagcg ttcagacagg agtgacagca acggctgtta tgatgtttgt tgtaatttcg
     6601 ggcggagtgc tttttgccct tgcagagcgt aaaaagagaa tataacacac tgacagccat
     6661 ttgtgcaaag attatcagtt gtctattgaa aaatttgtaa atatgatata aaatagcaat
     6721 aagtagaaaa atacggtttt tccgctgatt tatattaata ctgaaagagg tgccggaatg
     6781 gataaaaaca aaaaattatt ctacacaatc atcggtgcaa tctctgcact tgcggctgcc
     6841 acagcagcat ttctcgcttt aaaaaagcac agatgcgcag aacagaagct tattgaggaa
     6901 attgacgata ttgtttccga aaaagagcct gaggaggctg caaaggaaga accgctggca
     6961 gaagttacag ccgatgagct tgctgaggaa gaataagcaa caagttgttg cacccaattc
     7021 gggtagcagt atttgcatgt gaaaaagtta aatacccgag cggtgctttc aattaagaat
     7081 tgaaagttga aaacagataa taatgtcggc ggtgtgccac cgcagtctat tcaagaaaac
     7141 agtttaaaaa agaaaatgca tcagttgccc gaaaagctct gatgcatttt tgttttgtgc
     7201 gaagtaaccg taagccttaa ttctctctga atttaagata aatggcatag acagcctttt
     7261 taattttttg aattggcgta agcttgaaac ccttcttttt cataagactg agaatttctg
     7321 cataatagtc cttgttctga tgtttgagaa catagtccat atatttgttc ttgtctctgt
     7381 aaaatttcgg aatatcaaaa acattcttat acagttcaag ttttccgagt agcataagct
     7441 caaattgcgt tctgacgcac ttttcacagt gaccgcagtt gttctcaccg tagtaacaca
     7501 cattgaggtt atcatatgta atcggaaatt ttgaaatgaa gtcaaccttt tcaagcctag
     7561 tcttttcaag ccctgtaatg taaaaatcgg tactttcggt actcagcata cttgccgtaa
     7621 atgcctcata gtgtgccgag ccggtgtcgc attgttttat cgaaaaactg cttatcgggt
     7681 atccagacgc atagtaatag tttttgaaaa atttctgcat acacaagacc gccgaaaagc
     7741 tgcaataatg atgaaccttt acatacggca gggtaagatg ttcaccgaga tttgaattaa
     7801 tgtcaatcaa cggcatatca aagatttttg cggatttttt tgcaatttca agacgatttt
     7861 cgtacagctc ggcagattgt tcgggtgtgt aattagccgt acttctgtgg gagccgacat
     7921 tgaaaaaggt aagatgactc agcttttccg ttctgttttc ggaaagactg caaattgtgt
     7981 caaatgaatc cacacctctc gaaaatcctg ttgccgacgc atttttgcag cagtagtttt
     8041 cctgtgtaag ctcttttgca gatatcgaaa ttttgttgaa taattttgaa ttttttgtaa
     8101 gaacgggaat gaaaatttca ttaagctgaa aacacagttg cttcgacatc tttgcttctg
     8161 ccgaaatatt cagactgttg ttcattgcat acggcaacag tgcaacaacg aatgcgtcgg
     8221 cactttcggt cagatagtca gcatactttg tatcaacatc aaaccagaga gtgtaggaag
     8281 gctttccgtt ttcgctgatt tttgaacaga gtctggcacg attatcaagt ttttcaattt
     8341 tcggtttgcc gataatcaat gtttccatac ttttaccctc aaattaatct ctgaaaaaca
     8401 aatctcttgt gtaaaccttt tcttttacac agtcaagaac ggagctgtat ctgtttgcaa
     8461 cgattacatc cgattttgtg acgaactttt caaagtcgtt ttcaacgcca aagccctcga
     8521 ataaatcgac tttaagtgtc ggttcgtaga taattaactc gatgccgtta tttttcaaaa
     8581 gctccataac gctctgaatt gagctttgtc tgaagttatc ggaatttgac ttcattgtaa
     8641 ggcggtaaat tccgacagct tttggatttt tattcattat ctgtgatgta ataaattctt
     8701 ttcttgtctt gttagatgtt acaacagcgc tgattatgtc attcggaaca tccgaaaaat
     8761 tggccttgag ctgttttgta tcctttggca gacagtaacc gccgtagcca aaggacggat
     8821 tgttgtagtg atttccgatt ctcggatcaa gacacacacc gtcaatgata cttttagtgt
     8881 taaggttctt catttcggca tatgtgtcaa gctcgttgaa aaagctgaca cgcattgcaa
     8941 ggtatgtatt tgcaaaaagc tttaccgcct ctgcctctgt gtagtccata aagagagtgt
     9001 ctatgttttc cttaattgca cagtctgcaa gtgctgttgc aaaagtctcg gcagattttt
     9061 tcagttcttc atttgccata tcaacaccga caatgattct tgacggatag aggttatcat
     9121 agagagcctt gccctcacgc aaaaattcgg gactgaaaag gatttttgtg tatttgtatt
     9181 tttcaataac actttttgtg tatccaaccg gtatagtgga tttgataact ataaccgcat
     9241 ttgggttgca ttcaattaca agcttaatta cagcctcaac ggacgatgta tcaaaaaagt
     9301 gtctttcgtc atcgtaattg gtaggagtag agataattac aaaatcagca tttttgtacg
     9361 cagattttgc atcgacggtt gcaaccaaat ttaatttttt gtcagcaaga tattcttcga
     9421 tttccctgtc ggcaatcgga gatttctttt cattgattaa ctttaccttg ctttcaacta
     9481 catcaacagc ggttacctcg tgtttctgcg aaagaagtac agcgtttgaa agacccacat
     9541 accctgtccc ggcaattgct attttcattt ggtttcacct gattactttt ttaataattt
     9601 ttttgccttt tgaatctgtg acggactgag aattgacttt gctttttcca tcatcttgag
     9661 cttcattccg ccaaatttca ttctgttgtc atgaaaaagc ctgttaataa gctttgcgtc
     9721 ctcttccata tcggtgaaaa tctcaacaaa aatcggtcgg tcggattctt ctgcgagtgt
     9781 gggaataatg ttgtcaactt cttccttggt tgttgcgctg taatagtcat atccgagtga
     9841 ttcaatccag ccctttgcgc ccttgtgatg ttcggcgcag atgtactgat tgattgtagg
     9901 aatcttttcc ttgcccataa agaagtgaaa ttctgaaccg ccgccgttgt tgagaagaat
     9961 aattctcgca ttgttcttga ttcctctgat gcctgcggag ttcatatcat agaagaaact
    10021 gaggtcgccc acaacgcaaa aggcaagctc gtctgttgcc gatgcctgtc cgaaaaacga
    10081 agacatacag ccgtcaatac ccagagcgcc gatattgctg taaaccttga cattcggttt
    10141 caaatcgaag aactgcatag ttcttgtact gctgagaatt gcaaggtgca gaacagaacg
    10201 gtcgggaata atttcagcaa gctttttggc aacatacata tttgagaacg gaagattgct
    10261 tgaataatca agcattttga tatcgtcatt ccacatattg tagtatgtca tatcattttt
    10321 tgaattctgc ggtgcgttct ctgcaaagca gttaaagaaa tactgcggtg tacattcaaa
    10381 tacatctgtc agcttgtcgg aaaaatctct gattcttccc gcagtatcaa tttgccagtg
    10441 aacaaatttt tccttgtgag ccttaatcat aggcttgagt ttatatgaag caatattgtt
    10501 gccgaacgaa ataataagat cggggcataa ctcgccgaac attccctgca ttgagcattc
    10561 tgacaaagga taggtcataa ggcagccctt gcacttgagg tttgacatat gctcaaccga
    10621 tataaggcaa ttgtatttct caaagaactt ctcgacgcac gctctgtcat cttccgagaa
    10681 acagttgttc tgaccggcaa tgacaagaat tttcttatat tttgaaagcc tttctgcata
    10741 ttcacgccac ttctcggagg gcatatcggg agaaattctg ttgattttcc taacctgagg
    10801 aagattttca caatcatata cagccgagtt ttcaacaatc ggaatattga tatgcacagg
    10861 tcctgttccg tgatggtcaa gctccgaaag agcctcgtta ataagtcttt cgcagtacca
    10921 tctgtcattt ccgccacgca caacgggaag attaacggat ttttttgtaa ccgattcaaa
    10981 aatattgacc tgctgggttt tctgcagcat aagctgattt aatctgtacg ggtctttgtc
    11041 agcggtaatt gcgacaatcg gaacatcctg ataaaatgcc tctgtcatac ccggaagata
    11101 gttgcttaca gccgtacccg aggtacagat acaggcaacg ggggattttg tctgctgtgc
    11161 aagtccgatg ccgtaataca cggcacttct ctcgtcaacg accgaatgac actcaaaaaa
    11221 atcgtcattt tcaagtgaat gaattatagg aatatcactg cctccgggag aaagcaccaa
    11281 tttgttgata ttatattttt tcagaagtgc agtgagcaac tgaatgcttt ttattgtaga
    11341 atacatacgc tttcctccgc tttagttttt gataattccg gaaccgcctg taatcagagc
    11401 ggttttgccg tcaagaatat tgttgttctc cttctgcaca tacacgggaa caacattttt
    11461 tgctttaaag gttttgatta tgccctgtct gacttttttt agtgtatttt taagactcat
    11521 tttaaccacc gctgacaaag gatttaagat aatccaaaga tattattgtc tggttcttga
    11581 ttttttcgtt cacatcgtac cagtttattt cggtttctcg gcagtttccg tcaacaattt
    11641 cacggttgat tccaagactt ttcaaaagac cttcggagcg gatgtttctt ccgcttttgt
    11701 tcttgaattc aacaaaaaga ttcttgttga aaataacaga aaacgctgtt ccgtgaaacg
    11761 agtttgtaac aacatattcg gcatttttga aacagccgac aaattcctca acagtaggtg
    11821 caacaatata atttataccg tgacttacag ggtgaggtgc atcgtttatg cagtaaacgg
    11881 gaaggttctt ttcttttgac agtttaatgg caaaatccac aagcgaaact gccggattag
    11941 ccgtaaaaat gaggatatac ggtttgtcaa tttttgaaac ggcaatcttt ttccattcgt
    12001 ctgccgaaat cagcagggta ggatcaagat gagtttcggc ggttctgccc gtgagttctt
    12061 ttacaagctt ttctccgctc ggttcacgaa ctgagaactt ctgaaaaccg ttcagccttt
    12121 ttttatattc atcaataaat tcatcgggca atgtcggaac ggcaaagctt gccgcatatg
    12181 aatacttctg tttgtcatcg gcaaatgtca gaaaataagc gggatcaaaa ccgacgcatc
    12241 tcggactcca tacctgatcg cttcccgaaa tgaacaagtc ataatcgttt ttaagctctc
    12301 tgatattttg cggagtatac gactttttac tctttacaag atagttattg aaaaacgact
    12361 taaaagcgtc tctgcgtttt gctcttcttc ttaccatgac acagcttttt gcaaaggatt
    12421 tcagaaggtc gtttttataa atgcgaaagg gtttgtagtc ggctgtgatt ttcggacaga
    12481 tatagtcaac aatttcacac tccgcaccga gcgatgaaac ggttttttgc aacgcatagc
    12541 tctgaagcac agcgccgtag ttcaatgcac ggtgaaatgt tacaatgcct acctttttca
    12601 ttatctgctt ccccctgatt gttttttgta caaaaaatat cccatgggat aaaatatgac
    12661 cgcaagagcc ctctttgaaa atgtgtcggg catctttttt atttcggaaa atcttttacc
    12721 gttgagtaag ccgtcacggg aaagtcccac aaattgtttg ataaagaact taggattgct
    12781 ctttgcgtaa tcccaacatt cgtttataaa gtggagtctt acgaaaatag tttccctgtg
    12841 agccgagtaa gcgttacccg tcaaagaatt ttcctgatcg tttatgtaat atcgcaacgg
    12901 tgtgtcaata aaacgggtta tatattttct tccgatattg tcccaataga tattttcggg
    12961 ataaaaatga agtcccgaaa cacacggata agggttggct ctgattattt caagttttgt
    13021 cattccccac atctcaccgt caattttata cttcaatctc aggtcaaggt cggaacagtc
    13081 aaatcgttct gacggcagag gacaaccgtt tgttttgccg ctttcgttac aggtgcggca
    13141 cgaaattccc ttgtattttg atctgtcttc atcgggaatt ttgttccatt cgtttataaa
    13201 tgtttcaagg gcatcgtctt ttacgctgtc atcggagtca atcgttataa agaattcacc
    13261 ctttgcaatc tgtgccgcaa catttgttgc aatgtgtttt cctttgttgg tctgatattt
    13321 ataggttatg ttaaagtcag gtctgtcgct gatgaatttc tcaaccgttt cttttgtgtt
    13381 gtcggctgaa ccgtcatcaa caattatcca ttcaaaattt ctgtatgtct gttttttcag
    13441 cgcctcatat aatctgggca gagtttttgc cctgttatat gacggtgtaa aaacggaaaa
    13501 agtatattca gtcattgcaa cctcaaaatg ataataattt agcttttctt aaacttcttc
    13561 ttaattttat ccttgataag aacgagttct tttcttgaga aaatgagcgg aacggaaacg
    13621 gcatatcctg ccagtccgct tgctgcacag agaagaagga atgacatcca gctgtttgcg
    13681 tgtacaaagc tgttgataaa gatgaacatg gtgataacaa cagcaaagca gaaccatccc
    13741 ctgaaaatag acctgtaata tgttgtaagc tttattttca aaatatgtgc ggcgtacaac
    13801 ggaacaaata ctatcgcttt aagaccgata aaaacagagc tgacgcctgc aatagcataa
    13861 acaccgagcg gtgtaaagtg tatgagcagt aaaacgataa taaccgtaag aacaccgcac
    13921 acaagcgaga taagaacgga ggccttgagc ttgttgcata cggtgaaaag gctagaaaga
    13981 gttcttgtgt gacaggtaaa taggtatgaa atacatacaa gcaccgacaa aatctgaatt
    14041 atggtaattt cgtccggaga tttggtcggc tgccacaatg tatagaactt gttgccaaac
    14101 gcaataaatc ccgcaagagg tgcagtcatg agaaaactca taatctttga cgaaaacttt
    14161 gtttcttcaa caagtaagtc cgtgttgtcc tttgcataaa ggattgtaaa tctgggagtg
    14221 aatatatttg caatggttgt aataaggtta tcaatgcagt gcggaacggt gtttgcaatc
    14281 gacaaaagtc ccatgagtcc cgctccgaga gtcaggttac agattaacag gtcaagacct
    14341 ctgttcagag ctgtgctgag ataaccgatt gacgaccaaa ttcctgcgga aatcagaact
    14401 tttaccagct tgaaactgaa aaggttgaag ttcatcttta cttccggcag aattttattc
    14461 ttgactttga tattggtaag caaaagaaaa attccgcttg caagtgacgc catagcgaga
    14521 aaatatactt ttgcgggaaa aaacgagaac aaaattacta caagcaagag cttgagcgta
    14581 tttgacgcaa tatcacggag ggaattgata tacagcttgt tttttacaaa tgccgcagta
    14641 gtaaatattg ccgtgataac gctgattata aatgttgcaa aagtgagcgc aaacaatatc
    14701 tttacgctgt caacaagatt ttcgggaaca ttcagtataa attcaatgtt gaatgtaata
    14761 attgacgaaa ccaaaagtaa aacgccggca ataatcaggt cggcaaccag aaccgagctg
    14821 aaatatcttg atgccttgtc aatgtttcct ttgctgtatt caattgaaat aaatctgccc
    14881 gacattgagt tgagagcaga tgttacaatg gtggcatact ggacaaagtt gtttgcaagt
    14941 ccgataaatc cgtaggtttc agaaccgagt tcctttacaa gatagggtgc aagaacaaag
    15001 ttaattcctg ttcctatcaa gaaagacact atggcggcaa ccatatttat tgccatttgt
    15061 ttacttgttg ataatttttt cataatatga ccttagtttt aactgattaa aattttggaa
    15121 aagcattgaa gagctgttct ttcttcagtt caacaacatc cggatcgatt ctgtaattat
    15181 ttttcacctc gctgattgta ggcatatcgc cgtttgaaca atcaaagggt gtgtgtgtaa
    15241 tgtcaaaggc ggagaggtaa tcattgtact tgtttccgtc accgaacata ttgtttgtaa
    15301 gggttatgtg catattggga atgtggaaac tgtcggcaac aatcataccg tgaaggctgc
    15361 ttgaaataat gtattcgcac tcgcctattt tttcgacaac cttttttggg ttttccttca
    15421 ggtcaataag cgttgaattt tcgtagttat caagaagttt tttcacaaca gggtgatcct
    15481 gttccttaaa gtgcgggata attccgacac gatacttttt ttcgggataa aatccaagcc
    15541 acctttcggc aagaagtcct ccgtcacctg tcggcacatc aagctttttg ccgagaatat
    15601 tttccattct ctgcaatgaa agtctgcccc tcagagcgtg tatatgtata tgtctgaaca
    15661 tcagccccaa atcaagctcg gcattgcctc ggataaagcc cgtactccat atgtggacat
    15721 tatcattcat aaaatgctca attttctgct ttgctctgat cctcggatat gttgagtaca
    15781 ttatgtggtc aagtgcagaa ccgattgcaa tcaggttaca gcttttaagg tcttttctta
    15841 caaccttgat gttaaacagt tcttcaagca tatctttatt aagaagatct cccatattcg
    15901 gaatcggggg atacattatc ttatatacca ttgtattttc tccgttgtat tatttgcgcc
    15961 gtgagcagaa gctctgatta agagatataa atatcggatt tgtcttgcat atgtatatca
    16021 gcgaataagt aataagcatc catatcgatg ttgttgccca tggttcggtg gaaatcagaa
    16081 gttttggaag tgttacgcac acaagcgtac agcacaacgc aaattctgac ttatctttga
    16141 ttcttgtgca tacaaccttt gccgtcagcg aaaggcttga atataccgga ataagtccga
    16201 atacaattcc gccttcaaag aggtattggt aga
//
