LOCUS       gnlProkkaHHFKEBNM_457  10577 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HHFKEBNM_457.
ACCESSION   gnlProkkaHHFKEBNM_457
VERSION     gnlProkkaHHFKEBNM_457
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 02:50:18
            Original ID  :: gnl|Prokka|HHFKEBNM_457
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 27963
            Orig. end    :: 38540
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10577
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10576]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10576
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10577
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10577
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             239..4948
                     /locus_tag="ctg457_19"
                     /transl_table=11
                     /translation="MVDNNTNTVINTNTVHMTEKQKVKEITDRLEEGLKELFESEKYKS
                     YLSTMSKFHNYSFNNTLLIAMQKPEATLVAGYKAWQKNFGRHVNKGEKAIRILAPMPYK
                     IKEERDKLDPVTGEMTFDENGMPQKEEVEVTIPAFRVVSVFDVSQTDGKPIPELEAQEL
                     LSAVEGYENFVQALMNVAPVPIGFEDIPGDSKGYFHTTENRIAVQENMSESQTLKTMVH
                     ETAHSMLHNKEISQDIDAPVKDRNTKEVEAESIAYTVCQHFGIDTSDYSFGYIAGWSSG
                     KDMKELKSSLDTIRRTSSELIKGIEGQLQEIQRDRDLMQDKSINGLEKESRLLIQNSDL
                     SEYSLVNVRGMDAAEIMEALSAMNDDDRLSVAAYLESRGAWTTEIANEETREFGEYHLD
                     VRYITDTNEIIDLKKEMAWEERAKEPIGADDVILKITHAEGFEIERITNKTPEEVQEIM
                     GALTKLEEKDRKNIHDCLESYGADYIPIIVDGGRNSGMPQFNDFEIDLNKKEVVMMNHL
                     SPAQQAEGIINRLEYAKTAFSDDERNLIVNYAYKLNDMEKTRELAEHIYYEETEGNQGA
                     ALAVIDAQAEIDALPDPMIGLSEMEDYGYTWNEMLPLTKERALELFEHDLPIYVLHEDG
                     SETTVEDRTQITEHEGIFGIEKKDWENERNFLTMQEELSENEAAKETRLLYGSTDKYGI
                     YQLKDDPELRQFRFEGTEALKRMGITKYNFDAIKRENYNLIYVGELSELQGQTQGETLE
                     AVFEKFNIDHPTDYKGHSLSVSDIVVLHEDGENTAHFVDSFGFTELPEFTRTLEGEKTQ
                     EADKAEMELTDEEKQFLETDNAPLIAKKFLAWDEIEDLGYRFFEDGYIDRFEPSEKALY
                     GDGMVPEPEIYDIARRMHGGEDIRKELAKALIGGYERVMGIGEDDAVAVFGNDAVTVTF
                     GNAKKQISYEEMGTAFLGLIEREYKDVEQARATEEQEEEIAEDATFGQSVQKPETESIE
                     DGDEIIDLGEEREQVLAEMKKAQGERQDTSGHDVQKPGMEDKEEPHETELAFQIADRYI
                     TIQETEGGYDYSIMGMDYKEIDGGVYDNPDISIREALNDIVEDLKAEPDHNGAKGNIEK
                     DSKLIPMDFDELLVKNMYADRVEGSTITNMQNTQSSVVADFKAKTDELFHEISEMNPAE
                     IEETVKVHVQAKIDEYGIDAQIVDAAVVGSRCRGLEREGSDLDVVVELSTNEREDDLFN
                     TFNEDGLHIGGIKVDINPITEQRTGSLETYLPQVEEYLEGIRMAREQAEKEVEVTLMVS
                     ECSEFHNYGEFYENISTVEEAIAIWKQIPPERLNAIPAIGINVHLPGTEPYEDSEIDIL
                     SGRRIDLEILEHIPDIKNNPKAMEVIAQLVAKLPEMEIDGVMSEEMEARVWELRMPGLD
                     KAGQLAVELDRFVYDYDIYSYRNDVHSMTENIAELTEMLNQGDTEHITEWLNEAISEGA
                     APEEEERAKELLEKLAEYTPLAKIEENAINGMEEQNYNMVDDVQGTGDSSFNNGVGEKA
                     QKEAAKREQEQPAARISLKARLAEKKAQVAGQNQDHDAQENSKNNQREM"
     CDS             4952..5179
                     /locus_tag="ctg457_20"
                     /transl_table=11
                     /translation="MKNEFTVEESNLISIYTEEGTASGLGSRAKVIKSISDAMEHLEDD
                     EMMELSLRVIVKLIDLTDQEFAELEFIVAE"
     CDS             5437..6222
                     /locus_tag="ctg457_21"
                     /transl_table=11
                     /translation="MEHTIAKDAFSGLSGNNAVYNAICIAVCDDEQFMCDMIEEKIKEM
                     LPDAVVCKFFSAQELLDSETQIDILFLDIQMPEMDGMEAARLFRRDWKQALIIFVTAAP
                     EYVFQAFDVGAFHYLVKPLSDDKFCEVFENAVQEIESRKKGNGELDEEYMMIQAGGDHT
                     KILLKDIIYAEVFNRKVIIHTVNGDTEYYGNLSNLEKKAGEDFFRTHRSYLIHFRFVHR
                     YDAASVTMEKGTVLIAKQNYPEFVKQYLKYNQRKGREIK"
     CDS             6219..7562
                     /locus_tag="ctg457_22"
                     /transl_table=11
                     /translation="MSPIELCWNITSYISIIVQLIAAGVCFGVFVLPYMQGRDKAVKTG
                     SVYGVVMTVLYIMPPQIDNILAYFIGTVAAFAVMYVEDRQNINQKIFLSVTFFTLRWLS
                     SSMAGIIDFFLDIVLFNSAIAAMSWLHYGLYVMTRIMDILFCSLLLLLSIQAVNRAYEY
                     KNRYMGKKELLMLIVPSLLGMVGYMIFHFYQVKSEMTGFYDVLCFLYYLMSIIAILVII
                     VFFQNWKSLQEEQLGQELLESQINNIKMHIKEVEKLYGDLRAMRHDMGNHIQMIERLMG
                     ADNSSEAFAYLGRLKSEWQELTPEIRTGNPVTDMILLEKSNEAQMRGIRFECDFRYPEN
                     TKLDVFDVCIILYNALNNCMESVNGEKPYIKVHAFRKNSIFMLIISNSFKGRLRIDPAE
                     GIPYTAKKNGEHGIGLKNMRRVAKKYMGDLSFEQNGDEVTVGIMLQIV"
     CDS             7719..8564
                     /locus_tag="ctg457_23"
                     /transl_table=11
                     /translation="MTINGISGANTQAAQIGMNQAMDSYSKNIQNQIANAQKQLQELSS
                     NEEMTLEEKMKKRQEIQQQISDLNMQLRQHQIEQRKEQQSKGASMDDMLGGNRTAAKSG
                     NKGSGLSQASMQAMISTDSSMKQAKVQGSVATQMQGRANVLKAEIKQSGSTEAKEAELA
                     DLEQKAVNATASQMNTLAEANKAVSEAAAAERTEKKTSDAKEEKEAQAEGKTEKTADSG
                     AIGEKAQDGISGADAQTGNIENVQQDNGAQAQNIQPAQTAVPETPAAQPAVYTHVDVRL
                     "
     CDS             8579..9460
                     /locus_tag="ctg457_24"
                     /transl_table=11
                     /translation="MSEINSFSDYASKYNTNMDYSSLFGGGAPYIDNGMGGINVSDYAM
                     IKNGSYGKLMKAYYAKQDADKLSQFGDSSKTLTLMRSSADSLKKSAEVLGDVSLYEKKK
                     FKKKDEETGEEIEVEDYDWDAITKAVKTFVDDYNSVVEQAGNSETKNVLRNASWMTGIT
                     EKAGNLLSKVGITIGKGNKLEFDEEGLKKKTTLGESGIEFDNISTLKSLFTGYGSFASQ
                     IEQKASAISSAAARTKGVDQTYNKSGAYSDTLSKLFGSTVDEKVGDKFKDKDTVKDKNK
                     DKEKDKSSDKTS"
     CDS             10001..10576
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg457_25"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     3.8e-20, bitscore: 63.0, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.5e-11, bitscore: 35.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVPYIHTFYTPKGYYFYDFNTNAIVRINKSVYDFLNEWEKNKDC
                     PNSQSECGNIIDELKRAGFLSERHWTKIEHPATKMLDRYLHSSVESITLQVTQQCNLKC
                     NYCPYSGSYYNREHSNRHMSFETAKQAIDFYIAHSFDIPVAHIGFYGGEPLIEYDLIRK
                     IVEYCREKCFGKKIMYFMTTNANLLTEEV"
ORIGIN
        1 taccgggata acagtttctc acagtttgat acacgtcaga ctgcatcggg aacaacagaa
       61 ccgcatgagc ttgtgcagct gctgcgcttg ctctaataca atttaatagc aactaaaagg
      121 tgtatggaaa gagtatcaat agccatgcac cttttttatt tcaggaatac cgtcttgtga
      181 atttacaggg cggtattttt gcgtgcaaaa agagtaaaag ctctggaaag gaaaaactat
      241 ggtagataat aatacaaaca cggtcatcaa cacgaacaca gttcatatga ccgagaaaca
      301 gaaagtaaaa gagatcaccg acagactgga ggaaggctta aaagagcttt ttgagagtga
      361 aaagtataaa agttacctct ccactatgtc aaaattccac aattacagct ttaacaatac
      421 gcttctgatc gccatgcaga agccggaggc gactttagtg gcaggctaca aggcgtggca
      481 gaaaaatttt ggcagacacg tcaacaaagg cgaaaaagca atccgtattc ttgccccgat
      541 gccttacaag atcaaggagg aacgggataa gttagaccct gtgaccggag aaatgacctt
      601 tgatgaaaac ggtatgccgc agaaagagga agtggaggtt acaatcccgg cattccgtgt
      661 ggtatctgtc tttgacgtgt cacagacgga cggcaagccc ataccggagc tggaggcgca
      721 ggagcttttg tctgcagtgg aaggctatga gaactttgtg caggcactta tgaatgtggc
      781 tccggttccc attggctttg aggacattcc cggagattcc aaaggatatt ttcatacaac
      841 ggaaaaccgg attgcggtgc aggagaacat gagcgagagc cagacactga aaacaatggt
      901 gcatgaaacc gcacattcta tgctgcataa caaggaaatc agccaggata ttgacgcacc
      961 tgtaaaggac aggaatacca aagaggtgga agcggagagc atcgcttata ccgtctgcca
     1021 gcacttcggc atagatacgt cagattactc tttcggatat attgccgggt ggagcagcgg
     1081 aaaggacatg aaagagctga aatcttccct tgatacaatc cgcagaactt catcggagct
     1141 tattaagggc attgaagggc agcttcagga aatacagcgt gaccgggatt tgatgcagga
     1201 taagtccata aatggactgg aaaaggagag ccgtctgctg atacagaaca gtgatctgtc
     1261 cgagtacagc cttgtaaatg tcaggggaat ggatgcggcg gagattatgg aagctctctc
     1321 tgccatgaac gatgatgaca ggctgagtgt tgctgcatat ttggaaagta gaggtgcatg
     1381 gactacggag attgccaatg aggaaacaag ggaatttggg gagtaccacc ttgatgtccg
     1441 gtacattacc gatacaaatg agataattga cttaaagaaa gaaatggcat gggaagaaag
     1501 ggcaaaggag ccaatcgggg cggatgatgt gattttgaag attacccatg cggaaggttt
     1561 tgagatagag cgcattacca ataagacacc ggaggaagta caggaaatca tgggtgcgct
     1621 tacaaagctg gaagaaaagg acaggaagaa tatccatgat tgtctggaaa gctatggggc
     1681 tgattatatc cctatcattg tggacggcgg cagaaattcc ggtatgccgc agtttaatga
     1741 ctttgagatt gacctgaata aaaaagaggt agtaatgatg aaccaccttt ccccggcaca
     1801 gcaggcggag ggtatcatca accgtctgga atatgcaaag accgcttttt ccgatgatga
     1861 gcgtaacttg attgtaaatt atgcctataa gctgaatgat atggaaaaga caagggagct
     1921 tgcggaacat atctattatg aggaaacgga aggcaatcag ggagcagccc ttgcggtcat
     1981 tgatgcacag gcagagattg atgcacttcc cgaccctatg atcggcttgt cggaaatgga
     2041 ggattacgga tatacatgga atgagatgct gccgcttacg aaagagaggg cattggaatt
     2101 atttgagcat gatttaccga tatatgtact gcatgaggac ggttctgaaa caaccgtgga
     2161 ggacagaacg cagataacgg agcatgaggg aatctttggc attgaaaaaa aggattggga
     2221 gaatgagaga aatttcctca caatgcagga ggagctttcg gagaatgaag cggcaaagga
     2281 aacccggctt ttgtatggca gcacggataa atacgggata tatcagttaa aagatgatcc
     2341 ggagctaaga caattccgct ttgaggggac ggaagcactg aaacgcatgg gcattacaaa
     2401 gtacaatttt gatgccatta aacgggagaa ttacaacctg atttatgtgg gtgaactgtc
     2461 cgaactgcaa ggacagacgc agggggaaac gctggaagca gtctttgaaa agtttaatat
     2521 agatcacccg acagactaca agggacattc cctttccgtc agcgacatcg tggtgctgca
     2581 tgaggacggg gaaaatactg cccattttgt agattccttt ggatttacgg agcttccgga
     2641 atttacaagg acgctggagg gcgaaaaaac gcaggaagca gacaaagcgg aaatggagct
     2701 taccgatgaa gaaaaacaat tccttgaaac tgacaatgca cctttgattg cgaaaaagtt
     2761 tcttgcatgg gatgagattg aagatttggg gtatcgtttt tttgaggacg ggtatatcga
     2821 cagattcgag ccgagcgaaa aagcgttgta tggcgatggc atggtgccgg agcctgaaat
     2881 atatgatata gcccgccgta tgcatggcgg cgaggatatt cgcaaggagc ttgcaaaggc
     2941 tcttatcggc ggatatgaac gggtaatggg aataggcgaa gatgatgccg ttgcagtgtt
     3001 tgggaatgat gcggtgactg tcactttcgg gaatgccaaa aagcagattt cctatgaaga
     3061 aatggggacg gcttttctcg gtctgattga acgagagtac aaagacgttg agcaggcaag
     3121 agccactgag gagcaggagg aagaaattgc ggaagatgcc acttttggac agagtgtcca
     3181 aaagccggaa acggagagca tagaggacgg ggacgaaatt attgatctcg gagaggaaag
     3241 ggaacaggtg cttgcagaga tgaaaaaggc acaaggagaa aggcaggaca cctctggaca
     3301 cgatgtccag aagccgggaa tggaagataa ggaggaacct cacgaaacag agcttgcatt
     3361 tcagatagca gaccgctata tcaccataca ggaaacagag ggcggctatg attattccat
     3421 tatgggtatg gattataaag aaatagacgg cggcgtgtat gacaatcctg atattagtat
     3481 cagggaagca ctgaatgaca tagtggagga tttgaaagcg gaaccggatc ataacggtgc
     3541 aaagggaaac attgagaaag acagcaagct gataccgatg gattttgatg agctgcttgt
     3601 taaaaatatg tacgctgacc gtgtggaagg ctccactatt acgaatatgc agaacacaca
     3661 gagcagtgtg gtggcagatt ttaaggcaaa gacggatgag ctgttccatg aaataagcga
     3721 gatgaatccg gcagagattg aggaaaccgt caaagtccat gtgcaggcga aaatagacga
     3781 atatggcatt gatgcacaaa tagtggatgc tgcagtagtc gggagcagat gccggggatt
     3841 ggagcgtgaa ggctctgacc ttgatgtggt agtggagctt tccacaaatg agcgtgagga
     3901 cgatttattt aacactttta atgaggacgg acttcatatc ggcgggataa aggtggatat
     3961 taacccgatt actgaacaaa ggacgggaag ccttgaaacc tatcttccac aggtggagga
     4021 gtatcttgaa ggtatcagga tggcaaggga gcaggcagaa aaagaagtag aagtaacctt
     4081 aatggtatcg gagtgcagcg aatttcataa ttacggggaa ttttatgaga atatttccac
     4141 cgtggaggaa gccattgcaa tctggaagca gataccgccg gagcgtttga acgccatacc
     4201 cgcaatcggt atcaatgtcc atttaccggg aacagaaccc tatgaggata gtgagattga
     4261 cattttatcg ggcagacgga tagaccttga aatcctagag catatccctg atattaagaa
     4321 caatccgaag gctatggagg ttattgcaca gcttgtggca aaactgccgg aaatggagat
     4381 agacggtgtg atgtcagagg aaatggaagc gagggtttgg gaactgcgta tgccggggct
     4441 ggataaggcg gggcagcttg cagtagagct tgaccgtttt gtgtatgatt atgatatata
     4501 tagttatcgt aatgatgtgc atagtatgac cgagaatata gcggagctta cagagatgtt
     4561 aaatcaggga gatacggaac atatcacaga atggctaaat gaagcgattt ctgaaggagc
     4621 tgcaccggag gaagaagaac gggcaaaaga actgcttgaa aagctggcag agtatacgcc
     4681 ccttgccaag attgaagaaa atgccataaa tggcatggaa gaacagaact ataacatggt
     4741 cgatgatgtg caaggaactg gggacagttc ctttaataac ggtgttggtg aaaaagcaca
     4801 gaaggaagcg gcaaagagag agcaagaaca gcctgccgca aggatttctc taaaagcccg
     4861 ccttgccgag aaaaaagcac aggtggcagg acagaatcaa gaccatgatg cacaggaaaa
     4921 cagtaaaaat aatcagaggg agatgtaagc aatgaaaaat gaatttaccg tggaagaaag
     4981 caatttaatc agtatttata cggaagaagg tacagcttcc ggtttgggaa gcagggcaaa
     5041 ggtcataaag agtatcagtg atgcaatgga gcatttggaa gatgatgaga tgatggaatt
     5101 atcgcttcgg gtgattgtaa aactgattga cttgacggat caggaatttg cggagctgga
     5161 gtttatagta gcagagtaaa atttgaatgg gcagagcatg gcttttgtgg ctgtgttctg
     5221 cttttttatt gtatgaatat ctttgaataa gagcagaggg agcaggcaag gcagagaata
     5281 ttgtcggtta attcaagccg ataaattgaa ccccgaaatg atttattgcc ggaggaattt
     5341 ttttcacaac aaaataaggg ttgtttacaa catacataag cagatgcgga attgtgtgat
     5401 ataatttaag aaaaattata gaaggatgtg atgcatatgg agcatacgat tgccaaagac
     5461 gctttttctg gcttgtcagg caataatgca gtttacaatg caatttgcat tgcagtttgt
     5521 gatgatgaac agtttatgtg tgatatgatt gaagaaaaaa tcaaggagat gctgccggat
     5581 gcggtagtat gcaaattttt ttcggcgcag gaactgcttg acagcgaaac acaaatagat
     5641 attctgtttt tagacataca gatgccggag atggacggaa tggaagcggc aaggcttttt
     5701 cgtagagatt ggaaacaggc actcatcata tttgttacag cggctccgga atatgtcttt
     5761 caggcgtttg atgtaggtgc atttcattat ctggtcaaac ctttgtcaga tgataaattc
     5821 tgtgaagttt ttgaaaatgc ggttcaggag attgaaagca ggaagaaagg aaatggagaa
     5881 cttgatgaag aatatatgat gatacaggca ggaggagacc atacgaaaat actgctgaag
     5941 gatattatct atgcggaagt gttcaaccga aaagtcatta tccataccgt aaacggcgat
     6001 acagaatatt atggcaatct gtcaaatctt gagaaaaagg caggggagga tttttttaga
     6061 acgcatcggt catatcttat tcattttaga tttgtacata gatatgatgc tgcatctgtt
     6121 actatggaaa agggaacagt gttaatcgct aaacagaatt atcctgaatt tgtgaaacag
     6181 tatttgaaat ataatcagag gaaaggcagg gaaatcaagt gagtccgata gaattatgtt
     6241 ggaatatcac atcttatata tcaattattg tgcagcttat cgctgccggc gtttgttttg
     6301 gagtatttgt attaccctat atgcagggca gagataaagc agttaagacg ggaagtgtgt
     6361 atggggtggt aatgacggtt ttatatatca tgccgccaca gatagacaat attcttgcat
     6421 atttcattgg aacagtggcg gcatttgccg tgatgtatgt ggaggacagg cagaatataa
     6481 atcaaaaaat atttttgtcg gtcactttct ttacgctgcg ttggctgtcc tcttctatgg
     6541 cagggattat agatttcttt ctggatattg ttcttttcaa ttcggcgata gcggcgatgt
     6601 catggctgca ttatggactg tatgtaatga caagaattat ggatatactg ttttgttcgc
     6661 tacttttgct gttgtccatt caggctgtca atagagctta tgagtacaag aacagatata
     6721 tgggaaaaaa ggaacttttg atgctgattg tgccatcgtt gttaggcatg gttggctata
     6781 tgatttttca tttttatcag gtaaaatccg aaatgacagg attttatgat gtgctgtgtt
     6841 tcctatatta tttaatgtcc ataatagcaa tccttgtgat aattgtattc tttcagaact
     6901 ggaaaagctt acaggaagaa cagttaggtc aggaactttt ggaaagccaa ataaacaata
     6961 taaaaatgca tattaaggaa gttgaaaaat tgtatggaga tctccgtgct atgcgccatg
     7021 acatgggaaa ccatatccag atgatagagc gtctgatggg tgcggataac agcagcgagg
     7081 cttttgcata tctcggaagg ctgaaaagtg aatggcagga gcttacgcca gagatcagga
     7141 caggtaatcc ggttacggac atgatccttc tggaaaaaag caacgaagca cagatgcgtg
     7201 gaatccggtt tgaatgtgac ttccgttatc cggaaaatac aaagctggat gtttttgatg
     7261 tctgcattat cttatataat gcattaaata attgcatgga atcggtaaat ggagaaaaac
     7321 cttatatcaa agtccatgcg ttccgtaaaa acagtatttt tatgttgatc atcagcaata
     7381 gttttaaggg caggcttcgg attgacccgg cagagggaat tccgtatact gccaagaaga
     7441 atggtgagca tggaatcggc ttgaaaaata tgcgtagagt ggcaaaaaaa tatatgggtg
     7501 acttgtcatt tgagcagaat ggggatgagg tgacggtggg aatcatgctc cagattgtat
     7561 aaatggttta caacgaaata agggcggttc acaacatatc ggttgattag cacaagtaat
     7621 tttccgataa atttgttaga gaatagaaaa tctataacat taattatagg ctacttggga
     7681 aagggatttc aaatttattt atcaaggagg acgaaacaat gacaattaac ggaattagtg
     7741 gagcaaatac gcaggcagcg cagataggga tgaatcaggc aatggattct tacagcaaga
     7801 acattcagaa ccagattgcc aatgcacaga aacagttaca ggagctttct tccaacgagg
     7861 aaatgacgtt agaagaaaag atgaagaagc gtcaggagat tcaacagcag atcagcgact
     7921 tgaatatgca gcttagacag catcagattg agcagagaaa agaacagcag tctaagggtg
     7981 catctatgga cgatatgctc ggcggaaatc gaacagcagc aaagtcggga aataagggaa
     8041 gcgggctgtc acaggcaagt atgcaggcaa tgatttccac agattcttcc atgaagcagg
     8101 caaaagtgca gggcagcgtg gcaacacaga tgcagggcag agcgaatgtt ttaaaggcag
     8161 aaataaagca gagtggaagt acagaggcta aggaagcgga gctggcggat ttggaacaga
     8221 aagccgtaaa tgcaacagcc tcacagatga atacacttgc agaggctaat aaggctgtca
     8281 gcgaagctgc agcagcagaa cgcactgaga agaaaacttc tgatgcaaaa gaggaaaaag
     8341 aggcacaggc agaaggcaag accgaaaaga cagcagacag cggtgcaata ggagagaaag
     8401 cgcaggatgg catatcaggt gcagatgcac agacaggaaa tatagaaaat gtgcagcagg
     8461 ataacggcgc acaggcacag aacatacagc ctgcccaaac agccgttcca gaaactccgg
     8521 cggcacagcc agcagtttat acccatgttg atgtccgttt gtaaaggagg taaggcttat
     8581 gtcagaaata aacagtttca gcgactacgc aagtaaatat aacacaaata tggattattc
     8641 ttcgttattt ggcggcggtg ctccctatat agataatggc atgggcggga tcaatgtgtc
     8701 ggactatgcc atgattaaaa acggaagcta tggaaaactg atgaaggctt attatgcgaa
     8761 acaggatgcg gataagctgt cacagttcgg tgattcttcc aaaacactga cgctgatgcg
     8821 ttccagtgcg gactcgctga aaaagtctgc ggaagtgttg ggcgatgtct cgctttatga
     8881 gaaaaagaaa ttcaagaaaa aggacgagga aaccggagaa gaaatcgagg tcgaggatta
     8941 tgactgggat gcgatcacaa aggcggttaa aacctttgtt gacgattaca attcggtggt
     9001 agaacaggca ggaaattcag aaacgaagaa tgtgctgcgc aatgcgtcat ggatgaccgg
     9061 tataacggag aaggcgggca atctgctctc gaaagtaggc attaccattg gaaagggcaa
     9121 taagctggag tttgatgagg aaggcttgaa gaaaaaaaca acgttaggag aaagcggtat
     9181 tgagtttgac aatatttcta ctttaaaatc cctgtttaca gggtatggct catttgctag
     9241 ccagattgag cagaaagctt cggcgatatc cagcgctgcg gcgaggacaa agggagtgga
     9301 tcaaacctac aataagagcg gggcttattc cgacacgctg tcgaagctgt ttggtagtac
     9361 cgtggatgaa aaagtgggtg ataagttcaa agataaagat acggtcaagg acaaaaacaa
     9421 ggataaagag aaagataaga gttctgataa aacttcttaa atccaagaca gataaaaaag
     9481 cgatgagaaa gattgagttt gcgctaatca caatggcttg atatacaata tatattaacc
     9541 ataaatatat tgtagtagga aggaggtgac aaagatgagg aagttaggaa aaaaggttac
     9601 tctggataag aggtccttgc aggcatacaa gttctgcgta tgttcaaatt gcccatgccc
     9661 ttcaggcacg agcagctata gcgcaaaggc atctgattca gaaagaaaag caccaacgaa
     9721 ttagggcttg aagtaggcga catctaaact ctagatgcca tatgtgaagg gaagcatata
     9781 ttcagtacct atgcgtatgg catttggagc gatgatagag cggaggtttc tgattacgga
     9841 agaagatgac aaagatgagc aagctagggg gacatgtcct tcaggcacga gtagctataa
     9901 tgcaaaggca tctgattcag aaagaaagac accaacaaat taagtttaaa acatgcggca
     9961 tctaatcttg gatgccgcaa tgctatagga gaaaaaataa atgtcagtac cttatattca
    10021 tactttttat actccgaaag gatattattt ttatgacttt aataccaatg caatagtccg
    10081 aattaataaa agtgtatatg attttctgaa tgaatgggaa aaaaacaagg attgtcctaa
    10141 ttcgcaatcc gaatgtggaa atataataga tgaactaaaa agagcgggtt ttctgtcgga
    10201 acgtcattgg accaagattg aacatcctgc aactaagatg ttggatagat atttgcatag
    10261 ttctgtggaa tcaattactt tacaggtaac acagcagtgt aatttaaagt gtaattattg
    10321 tccctattca gggagttatt ataatagaga gcatagtaac aggcatatgt catttgaaac
    10381 agctaaacaa gcaattgatt tttatattgc acattctttt gatattcctg ttgctcatat
    10441 tggattttat ggaggggaac ctttaataga atatgatttg attcgcaaaa ttgttgaata
    10501 ttgtagagaa aaatgttttg gcaaaaaaat aatgtatttt atgactacaa atgcgaatct
    10561 tcttacagaa gaagtaa
//
