LOCUS       c00254_gnlPro..         6924 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HHFKEBNM_254.
ACCESSION   c00254_gnlPro..
VERSION     c00254_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:50:07
            Original ID  :: gnl|Prokka|HHFKEBNM_254
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6924
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6924
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1248:6687]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1249..6687
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..6924
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6924
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             2..1180
                     /locus_tag="ctg254_1"
                     /transl_table=11
                     /translation="SQGLPDLREIPSCVGGDPKKRTGIVVAKSIPAKKYGIQTGEPVAM
                     ALRKCPNLVIVPSDFELYDKCSRAFKAICASFAPVMESFSIDEVFLDMTGTSLIYPDPV
                     AAAHELKDKIHRELGFTVNVGISTNKLLAKMASDFQKPDRVHTLFPDEIPEKMWPLPIR
                     NLLFLGKASEQKLLNQGIRTIGDLARERASNVQYWLGEKTGHQLWQYARGIDDSPVKAV
                     PDEAKGFSVETTFNDDITSIEQVFPVLLEQCDVLATRMRRKDKKCNCISVTFRTLDFRN
                     RSHQTKLENATDLTDEIYINATRLFKEFWKGQPLRLIGVALTGLTDGTYEQMSLFEDTE
                     NKERRRKLDAAMDEIRMKFGNDKITRASIMNSNTRIGRKAKAQMKNEKTEEP"
     CDS             complement(1249..1758)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg254_2"
                     /sec_met_domain="ALS_ss_C (E-value: 2.6e-23, bitscore:
                     70.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKGMKKRWISLYVENQVGVLSKISGLFSGKCYNLDSLTVGTTED
                     PTVSRMTIATVSDDETFEQIKKQLNRMIEVIKVIDFTDVFVRMKEILYIKVFNCSKEDK
                     VELFQIAETFKAKVIDYGKDSLLLEFVQTATKNDAVVKLIKEEFHRIEVVRGGSVGIES
                     ISMMER"
     CDS             complement(1776..3494)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg254_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1e-49, bitscore:
                     157.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQISGNKLLVKALKEEGVEYLFGYPGACTIDISDELYKQDDVKI
                     ILPRHEQALVHEADAYARTTGKVGVCLVTSGPGATNLVTGLATANYDSVPLVCFTGQVA
                     RHLIGNDAFQEVDIVGITRSITKYGVTVRRREDLGRIIKEAFYIARTGRPGPVLIDLPK
                     DVMAELGSAEYPKNVNIRGYKPNTDVHIGQLKRAIKLLNKAKRPLFLAGGGVVISRAHE
                     IFREVVEKTKVPVVTTVMGKGSIPTDHPLYIGNLGMHGAYAANMAVSNCDVLFSIGTRF
                     NDRITGKLHEFAPHAQIIHIDIDTASISRNIQVDIPIVADAKEAITKMNEYVQECSTDK
                     WLNLIKNWKEEHPLKMRPNDLLSPMDILKEINEQFENSIIVTDVGQHQMLVSQYAEITE
                     GKQMIMSGGLGTMGYGLPGGIGAKIGNPDRPVIVISGDGGVQMNIQELATAVLEELPVI
                     LCIFNNEYLGMVRQWQKLFYGKRYAMTNLRAGALSRRTEGMEYPQYTPDFIKLAESYRA
                     KGIRVTKKEEIAAAFEEAKKNTKAPTVIEFIIDPEEMVYPMIKPGGTLEDMIMDC"
     CDS             4404..4958
                     /locus_tag="ctg254_4"
                     /transl_table=11
                     /translation="MDYLSNNVAVNLKRIRKSKSMSLDQVSEQTGVSKSMLAQIERGTA
                     NPSLGVLGKITSGLRIEFQELIQPPRVDCCLVTPAELVPTKEVAGQYRVWTCLPYEDTR
                     LVEVYRIEVEPGGVYISGSHGEKTREYLAVMEGVLTLECHGEKYEIHRDQVFKFETDQE
                     HVYRNTGKEKACCTCFFLDYH"
     CDS             5470..6687
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: Beta_elim_lyase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg254_5"
                     /sec_met_domain="Beta_elim_lyase (E-value: 7.4e-09,
                     bitscore: 23.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_3 (E-value: 9.3e-111, bitscore:
                     358.9, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLKDTGLTFQDIKDKVNKYMIETYERFDFLAETAEGMYIYDENK
                     TPYLDFYAGIAVNSAGNCNPKVVAAAKDQLDDIMHTFNYPYTIPQALLAEKVCETIGMD
                     KIFYQNSGTEANEAMIKMARKYGIEKYGPNRYHIVTAKMGFHGRTFGAMSATGQPGNGC
                     QVGFGPMTYGFSYAPYNDLQAFKDACTENTIAIMVEPVQGEGGVHPATMEFMQGLRKFC
                     DENDMLLLIDEVQTGWCRTGAVMSYMNYGIKPDIVSMAKALGGGMPIGAICATAEVAKA
                     FTAGSHGTTFGGHPVSCAAALAEVNELLDRDLAGNAKKVGDYFAAKLEKLPHVKEVRHQ
                     GLLVGVEFDDTIGGVDVKHGCLDRHLLITAIGAHIIRMIPPLIVTEEECDKAVAIIEDT
                     IKSLEK"
     CDS             6800..6922
                     /locus_tag="ctg254_6"
                     /transl_table=11
                     /translation="MKHLVITIGCEYGAKGNAIGKKIAQDLGIKFYDRDLVDEII"
ORIGIN
        1 gagccagggg ctgccggatc tcagagaaat tccttcctgt gtaggaggag atccaaagaa
       61 acggacaggt atcgtggttg ccaaatctat ccctgcaaaa aaatacggga tccagaccgg
      121 cgagccagta gccatggctc ttcggaaatg tcccaatctg gtgatcgttc ccagtgattt
      181 tgaattatac gataaatgtt cccgggcatt taaagcaatc tgtgcttcct ttgcacctgt
      241 gatggaatct ttttccattg atgaggtatt tctggatatg acaggtactt ctctgatcta
      301 tcctgaccct gtagctgctg ctcatgagct gaaagacaag attcacagag agctgggatt
      361 cacagtaaat gtgggaattt ctaccaataa gcttttggca aagatggcat cagattttca
      421 aaagccggac agagtacaca ctctgttccc ggatgaaatc ccggagaaaa tgtggcctct
      481 tcctatccgt aatctgctgt ttctgggaaa agcttccgag cagaagcttc tgaatcaggg
      541 gatccgtacc atcggtgatc tggcaagaga aagagcatcc aatgtgcagt actggcttgg
      601 ggaaaaaacg ggacatcagc tatggcaata tgccagaggt attgatgatt cccctgtaaa
      661 agcagtgcct gatgaggcaa aaggtttcag cgtggaaact acttttaacg atgatattac
      721 ttccatagag caggtgtttc ccgtactttt ggagcagtgt gatgttctgg caaccagaat
      781 gcgcagaaaa gataagaaat gcaactgtat ttccgtgact ttccgtactt tggatttcag
      841 aaaccgttca caccagacaa agctggaaaa tgctacagat cttacagatg aaatttatat
      901 aaatgctaca agacttttta aagaattctg gaaaggacag ccgctacgtc tgattggtgt
      961 ggcactgaca ggccttacag atggcactta tgaacagatg tctctgtttg aagatacgga
     1021 aaataaagaa cgccgcagaa agctggatgc agctatggat gagatccgga tgaaatttgg
     1081 aaatgataag atcacccgtg ccagtattat gaacagcaat acacggattg ggcgaaaagc
     1141 gaaagcacag atgaaaaacg aaaagacaga agaaccgtaa gtaaagggag gactgagcat
     1201 taagaataat gcgacaatcc tccctttata aaaatttcag aaaaagtttt atcgttccat
     1261 catactgata gattcgattc ctacacttcc tccacgtacc acttcaattc tgtgaaattc
     1321 ttccttgatc agtttcacta ctgcgtcatt cttggttgct gtctggacaa attccaggag
     1381 caggctgtct ttgccatagt caatgacctt tgccttgaag gtttcggcaa tctgaaacag
     1441 ttcaacctta tcttctttgg aacagttaaa aaccttaata tacagaatct ctttcatgcg
     1501 gacaaatacg tctgtgaaat caataacctt aataacctcg atcatacggt tcaactgttt
     1561 tttgatctgc tcaaaagttt catcatcact gacagttgcg atcgtcattc gggatactgt
     1621 agggtcttct gttgttccta ctgtaagact gtccaggtta taacattttc cggaaaaaag
     1681 tccggagatt ttggacagaa cacctacctg gttctcaaca tagagagaaa tccatctttt
     1741 tttcattcct ttatccataa taattttcct cctgatcaac agtccataat catatcttct
     1801 agagttccgc ctggtttgat cataggataa accatttcct cagggtcaat gatgaattca
     1861 attactgtag gtgcctttgt gttctttttt gcttcctcga aggctgctgc aatttcctct
     1921 ttctttgtga cacggattcc ttttgccctg tagctctctg caagtttaat gaaatccggt
     1981 gtgtactgtg gatattccat gccttctgtg cggcgggaaa gtgctccggc gcgcaggttg
     2041 gtcatggcgt agcgtttacc gtagaagagt ttctgccact ggcgtaccat tccaaggtat
     2101 tcattgttaa agatgcacag gataacagga agttcttcca gaactgcagt tgcaagctcc
     2161 tgaatgttca tctgcacacc gccgtcaccg gagataacga tgacaggtct gtcgggattt
     2221 ccgattttgg ctccgatgcc gcctggaaga ccatagccca ttgttcccag accaccggac
     2281 atgatcatct gtttgccctc tgtgatttcc gcatactggg agacaagcat ctgatgctgt
     2341 cctacatctg ttacgataat actgttctca aactgttcgt tgatctcttt caggatatcc
     2401 atcggactta aaagatcatt tggacgcatt ttaagcggat gctcttcttt ccagtttttg
     2461 atcaggttaa gccacttgtc cgttgaacat tcctggacgt attcgttcat tttggtgata
     2521 gcctcttttg catcagcaac aatggggata tccacctgaa tgtttcggga aatggatgct
     2581 gtatcaatat caatgtggat aatctgggca tgtggtgcaa attcatgaag ttttccggtg
     2641 attctgtcat tgaatctggt tccgatggag aacagcacat cgcagttgct gactgccatg
     2701 tttgctgcat aggcaccatg catgccgagg tttccgatat aaagcggatg gtcagtagga
     2761 atggaacctt tgcccattac ggttgtgaca accggtactt ttgttttttc tactacttcc
     2821 cggaagattt cgtgggcgcg ggagattact acaccgccgc ctgcaaggaa taaaggacgt
     2881 tttgccttgt ttaaaagttt gatggcacgt ttgagctggc cgatatggac atctgtgttg
     2941 ggcttgtatc cgcggatgtt tacattttta ggatactcag cgctgccaag ttctgccatt
     3001 acgtcctttg gaaggtcgat aaggacaggt cccggacggc cggtgcgggc aatgtagaag
     3061 gcttctttga tgatacgtcc caggtcttca cgtctgcgga cagtaacgcc gtatttggtg
     3121 atgcttctgg tgattcctac gatgtctact tcctgaaatg catcgttgcc gatgaggtgg
     3181 cgggctacct ggccggtgaa gcatacaaga ggtacgctgt catagttggc ggttgcaagt
     3241 cctgttacaa ggttggttgc tccgggaccg ctggttacca gacatacgcc gactttgccg
     3301 gtggttctgg cgtaggcgtc ggcttcgtgg acaagggcct gttcgtgacg ggggaggatg
     3361 attttgacat cgtcctgttt gtagagttca tcactgatgt cgatggtaca ggctccgggg
     3421 tagccgaaga ggtattctac gccttcttct tttaaggctt ttactaagag tttgttgccg
     3481 gatatttgtt tcatatttgg gtaaacctcc tttgggtatg tggatgggga cgctcggaaa
     3541 tttatttgtt ttcgggtgcg gtttcggagt ctaggaactc taagtgtctg aaaatctgct
     3601 aaaaccgttc agaaaaatct caaactcgcc gcagatgcgg ctcagacagt gagatttttc
     3661 tgaacaacgc agatttccag gcactaagag ttactacgac tcctgcaaat gcacccgaaa
     3721 acaaataaat ttccgagctg tgtattggcg aatacagggt ggggcagaat ggcgctgcgc
     3781 tgattctgcc gagtgtgggg cggcgggttt gatgtgacag atgtaaatga tgttagggtc
     3841 aaaaggtatt ttgaccctgg tatataaata tagtaaaaaa cgccctgggc ttgtttgccc
     3901 agggcgaaaa tgttttccgc ggtaccacct gtattcagag tctggctctg cactttgtca
     3961 gtactgatat actgtgttcc tgtaacgtgg aactgacgtt gaagcctact tggcatgtct
     4021 gtccgggtct atgaatcatc tgactggata tgcggtttgg ttcactgctc gggggctact
     4081 tccacaattc gttcacgaaa gctcgcaccg accgctttct ctctgtgctt cccggggttg
     4141 tgtactcctc cctgtcatgg catttggctg atatagggat attcattgtc cgaatagggt
     4201 ggacaaatgt tttcttgggt tacattatac atttatagag aggaaattgt caaccgggtt
     4261 ttatagaatt gctataaaat ttgtgttctt gaatgaattt tggctacttt actgagaacg
     4321 gaatgaatag taatgtaatt gacagatttc tatattgctg atataaaaaa gaaatagtac
     4381 agttgtttgg aaggaggaaa catatggatt atttatcgaa taatgtggcg gtgaatctga
     4441 agaggattcg gaaatccaag agtatgagtc ttgatcaggt gtctgagcag acaggggtga
     4501 gtaagagtat gctggctcag attgagagag ggactgccaa tccttctttg ggtgtgctgg
     4561 ggaagatcac cagtggtctg aggattgagt ttcaggagct gatacagccg ccgagagtgg
     4621 actgttgtct ggtgacaccg gcagagctgg ttcccaccaa ggaggtagca ggacagtaca
     4681 gggtatggac ctgtctgcct tatgaggata cacgtctggt ggaggtgtat cggatcgaag
     4741 tggaaccggg tggtgtttat atcagtggca gtcatgggga gaagacaaga gaatatctgg
     4801 ctgttatgga gggtgtgctt actctggaat gtcatggtga gaagtatgaa atccacagag
     4861 atcaggtgtt taagtttgaa acggatcagg agcatgtcta tcggaacaca gggaaggaga
     4921 aagcctgctg tacctgtttt tttctggatt atcattgatg cagttgtatc aggagttttg
     4981 ttgctgaagc ggtctgccgc aggtggatta ccatagtgta gaactgagta gtgaagcagg
     5041 tgattttatc cgaagtatga gtgtaaaatg tgtaatataa tgcacaaaat gatgaaaaag
     5101 atacaccagg aaatgaatat ctgaaaagaa aggatgtatg taatggtttg tcagtctgcc
     5161 atttcatgaa gaggctgtgt tgttatgaat tgttgagaaa cctttataat atcgcatgaa
     5221 tatgcaggaa atattggata tacaataagg agaacacaga gctttcgtta ctgttcactc
     5281 cgttctcagt aacgatcttt ctgtaaaaaa tgtaaatgtt caaaaaacat gttgacaaat
     5341 cataagggca gtgatattgt aaggatgtac aaaataatac acagaaaaag ttaagcaaag
     5401 gcgcttaccc atacgggtca gtttgtcttt gcttttttta ttatcttaag gatgcaggag
     5461 ggcacagcta tgaaattaaa agacacagga ttaacttttc aggacattaa ggacaaagta
     5521 aacaagtaca tgatcgagac ttatgagaga tttgatttcc ttgcagagac agcagagggc
     5581 atgtacattt atgatgagaa taaaacccca tatcttgatt tttatgctgg tattgcagta
     5641 aacagcgcag gaaactgtaa ccctaaggtt gtagctgctg caaaggatca gttagatgat
     5701 attatgcata cattcaacta tccatacaca atcccgcagg cgctgcttgc tgagaaggtc
     5761 tgtgaaacaa tcggaatgga caagattttc tatcagaact ctggtacaga ggctaacgag
     5821 gcaatgatca aaatggcccg taaatatggt attgaaaagt atggtccaaa ccgttatcat
     5881 atcgtaactg caaagatggg attccatgga agaacctttg gtgccatgtc tgcaacaggt
     5941 cagccgggta atggatgcca ggttggattc ggacctatga cttatggttt ctcctatgca
     6001 ccgtacaatg accttcaggc tttcaaggat gcatgtacag agaatacaat tgccattatg
     6061 gttgagcctg tacagggcga gggtggtgta catcctgcaa caatggaatt catgcaggga
     6121 cttcgtaaat tctgtgatga gaacgatatg cttcttctga tcgatgaagt acagacagga
     6181 tggtgcagaa caggtgctgt tatgtcctat atgaattatg gtatcaaacc ggatatcgta
     6241 tctatggcaa aggctctggg cggtggaatg ccaatcggtg ccatctgtgc aacagcagag
     6301 gttgcaaaag ctttcacagc aggttcccat ggaactacat tcggcggaca tccggtaagc
     6361 tgtgcagctg cactggctga ggtgaatgag cttctggaca gagatttggc tggaaatgca
     6421 aagaaggttg gcgattactt tgcagctaag cttgagaagc ttcctcatgt aaaagaagta
     6481 agacatcagg gacttctggt aggtgtggaa tttgatgata ctatcggcgg agtggatgta
     6541 aaacatggtt gtcttgacag acatcttctg atcacagcta tcggagcgca tatcatccgt
     6601 atgatcccac cgcttattgt tacagaagaa gagtgcgaca aagctgtagc aatcatcgaa
     6661 gatacaatta aatctctgga aaaataaaaa tccggcaacg gagtgataca gtaacaggac
     6721 aagggcgtca cgaattatat tcgtgcgccc ttttatgata tcagaatctg ataaaaattt
     6781 gagtgtgaga gggaagagca tgaaacatct ggtaattacg attggctgcg aatatggagc
     6841 caagggcaat gccatcggta agaagattgc acaggatctg gggattaagt tttatgatcg
     6901 tgatcttgtg gatgagatta tcaa
//
