LOCUS       c00088_gnlPro..        16332 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BJKJGAPA_88.
ACCESSION   c00088_gnlPro..
VERSION     c00088_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:49:33
            Original ID  :: gnl|Prokka|BJKJGAPA_88
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16332
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16332
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3339:6332]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3340..6332
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16332
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16332
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(575..1762)
                     /locus_tag="ctg88_1"
                     /transl_table=11
                     /translation="MKKKIFILLLCVVLIATCILCGVTGIFGNDSQNSPKPQTHDTAVT
                     ENMTFPSKVDSLTLKVGESKLIELSSEKAKSVTKWTSSDSKIVTVDDGGRVDALKEGTA
                     LISAISKDKSKSEFQVTVAKSTTKKQQSYSTCITANLDKLENNKRNTAKNLYAIKVNRT
                     ANCVTVYTYDEKGKYTIPVRAMICSTGLDNSTITGDYTIGIKSEWLSLVGDVFGRYISG
                     ISGDYLFHSVPYYSMSEEDLELEEFNKLGEQASQGCVRLAVSDAKWVYDNCPTGTNVSI
                     YDDAENAGPLGKPDAIKITDFTNKWDPTDSNKKCPYAKATPIISGANDYTIKSGGEFYA
                     LAGVTAVDTCGNDITSNIEVFGNVVTTRKGKYKVTYSVTDVLKRTSSVTITVTVQ"
     CDS             1927..2463
                     /locus_tag="ctg88_2"
                     /transl_table=11
                     /translation="MVIIMAHPIKHFRTITRHRHKVIANCARAGILRQGLIHDLSKYSP
                     TEFIPGAKYFQGTRSPNEKERELYGYSQAWLHHKGRNRHHYEYWNDYNPKTKQIENVEM
                     PVKYVIEMFCDRVAASKIYNGKNYTDGAPFTYFCRIRGKHRMHPNTEALLEKLLVMLRD
                     EGEEKTFAYIRSMKK"
     CDS             complement(2402..2647)
                     /locus_tag="ctg88_3"
                     /transl_table=11
                     /translation="VNSFLVTSKIFNHSSYNPVGFHIITPYGEPPYPIRVDRFLFVQFC
                     RGSIATIFQTGGFAQTITFSYFLYMQMSFLHPHLSA"
     CDS             complement(2666..2896)
                     /locus_tag="ctg88_4"
                     /transl_table=11
                     /translation="VSHKVTNFVNKCFFVAESSKQLFSLVRTFKFLILSCRRIVLFFAH
                     LYADVVNDCGDFKKLLIVGQKIFTFTDCLCE"
     CDS             3340..5577
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_5"
                     /sec_met_domain="Gly_radical (E-value: 3.6e-41, bitscore:
                     131.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.8e-271, bitscore:
                     892.9, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEWTNFAGGKWESDIDVRDFIQRNYTPYDGDQSFLEGPTEATD
                     KLWGELKELQKEERAKGGVLDMETEVVSGITAYGAAYLDKDLEKVVGLQTDKPLKRAFM
                     PYGGIKMAEQSCQMYGYTPSPKLHEIFTKYHKTHNQGVFDIYTPEMKLARHNKILTGLP
                     DTYGRGRIVGDYRRVALYGIDRLIEGKKEDFAETNRQGMRRGDFQLREEIADQIRALND
                     MKEMALSYGFDISQPAKNAAEAVQWLYFGYLAAIKTQNGAAMSVGRVSTFLDIYIERDL
                     ENGTLTESQAQELVDHFVMKCRMVKFARIESYNQLFSGDPVWATLEVAGLGIDGRSMVT
                     KNDYRFLHTLENMGPSPEPNLTVLYSSRLPENFKKYAAHISVTTSSIQYENDDVMRPVW
                     GDDYSICCCVSATQTGKEIQFFGARANLAKCLLYAINGGIDEKTKMQVGPEYTPITSEY
                     LDYDEVIKKYDTMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTDVRRTFATGIAG
                     FSHVVDSLSAIKYAKVKVIRDEDGVAVDFETEGDFPRYGNNDERADKIAVDLLKTFMAK
                     LKYCHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQNGLLA
                     SLNSVAKLPYEYALDGISNTQTINPGALGHNDDERVDNLVNVMDGYFDQGAHHLNVNVF
                     GTEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             5577..6332
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 76.2;
                     E-value: 1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_6"
                     /sec_met_domain="Radical_SAM (E-value: 2.5e-30, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNAVKGFVHSIETFGSVDGPGVRFVIFLSGCAMRCQFCHNPDT
                     WKHDENTVEYTADELLNKALAYRPYWKNKGGITVSGGEPLLQIDFLLDLFKKAKKQGVN
                     TCIDTSANPFTTKEPFYSKWKELMEYTDLLLLDIKHIDNEQHKILTGQPNTNILEMARQ
                     LSDMGKPVWIRHVLVPERNDKDEYLFRLADFIRSLKNVERVEVLPYHTLGVYKWKALGY
                     DYPLEGIEPPTKERVKNAEMILNGEKTRD"
     CDS             6877..7095
                     /locus_tag="ctg88_7"
                     /transl_table=11
                     /translation="MDKNKKLFYTIIGAISALAAATAAFLALKKHRCAEQKLIEEIDDI
                     VSEKEPEEAAKEEPLAEVTADELAEEE"
     CDS             complement(7316..8467)
                     /locus_tag="ctg88_8"
                     /transl_table=11
                     /translation="METLIIGKPKIEKLDNRARLCSKISENGKPSYTLWFDVDTKYADY
                     LTESADAFVVALLPYAMNNSLNISAEAKMSKQLCFQLNEIFIPVLTKNSKLFNKISISA
                     KELTQENYCCKNASATGFSRGVDSFDTICSLSENRTEKLSHLTFFNVGSHRSTANYTPE
                     QSAELYENRLEIAKKSAKIFDMPLIDINSNLGEHLTLPYVKVHHYCSFSAVLCMQKFFK
                     NYYYASGYPISSFSIKQCDTGSAHYEAFTASMLSTESTDFYITGLEKTRLEKVDFISKF
                     PITYDNLNVCYYGENNCGHCEKCVRTQFELMLLGKLELYKNVFDIPKFYRDKNKYMDYV
                     LKHQNKDYYAEILSLMKKKGFKLTPIQKIKKAVYAIYLKFREN"
     CDS             complement(8483..9667)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg88_9"
                     /sec_met_domain="UDPG_MGDP_dh_N (E-value: 2e-37, bitscore:
                     119.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="UDPG_MGDP_dh (E-value: 5.9e-29, bitscore:
                     91.4, seeds: 679, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAIAGTGYVGLSNAVLLSQKHEVTAVDVVESKVKLINEKKSPI
                     ADREIEEYLADKKLNLVATVDAKSAYKNADFVIISTPTNYDDERHFFDTSSVEAVIKLV
                     IECNPNAVIVIKSTIPVGYTKSVIEKYKYTKILFSPEFLREGKALYDNLYPSRIIVGVD
                     MANEELKKSAETFATALADCAIKENIDTLFMDYTEAEAVKLFANTYLAMRVSFFNELDT
                     YAEMKNLNTKSIIDGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLKANFSDVPNDIISA
                     VVTSNKTRKEFITSQIMNKNPKAVGIYRLTMKSNSDNFRQSSIQSVMELLKNNGIELII
                     YEPTLKVDLFEGFGVENDFEKFVTKSDVIVANRYSSVLDCVKEKVYTRDLFFRD"
     CDS             complement(9682..11445)
                     /locus_tag="ctg88_10"
                     /transl_table=11
                     /translation="MYSTIKSIQLLTALLKKYNINKLVLSPGGSDIPIIHSLENDDFFE
                     CHSVVDERSAVYYGIGLAQQTKSPVACICTSGTAVSNYLPGMTEAFYQDVPIVAITADK
                     DPYRLNQLMLQKTQQVNIFESVTKKSVNLPVVRGGNDRWYCERLINEALSELDHHGTGP
                     VHINIPIVENSAVYDCENLPQVRKINRISPDMPSEKWREYAERLSKYKKILVIAGQNNC
                     FSEDDRACVEKFFEKYNCLISVEHMSNLKCKGCLMTYPLSECSMQGMFGELCPDLIISF
                     GNNIASYKLKPMIKAHKEKFVHWQIDTAGRIRDFSDKLTDVFECTPQYFFNCFAENAPQ
                     NSKNDMTYYNMWNDDIKMLDYSSNLPFSNMYVAKKLAEIIPDRSVLHLAILSSTRTMQF
                     FDLKPNVKVYSNIGALGIDGCMSSFFGQASATDELAFCVVGDLSFFYDMNSAGIRGIKN
                     NARIILLNNGGGSEFHFFMGKEKIPTINQYICAEHHKGAKGWIESLGYDYYSATTKEEV
                     DNIIPTLAEESDRPIFVEIFTDMEEDAKLINRLFHDNRMKFGGMKLKMMEKAKSILSPS
                     QIQKAKKLLKK"
     CDS             complement(11621..12700)
                     /locus_tag="ctg88_11"
                     /transl_table=11
                     /translation="MKKVGIVTFHRALNYGAVLQSYALQKTVSSLGAECEIVDYICPKI
                     TADYKPFRIYKNDLLKSFAKSCVMVRRRAKRRDAFKSFFNNYLVKSKKSYTPQNIRELK
                     NDYDLFISGSDQVWSPRCVGFDPAYFLTFADDKQKYSYAASFAVPTLPDEFIDEYKKRL
                     NGFQKFSVREPSGEKLVKELTGRTAETHLDPTLLISADEWKKIAVSKIDKPYILIFTAN
                     PAVSLVDFAIKLSKEKNLPVYCINDAPHPVSHGINYIVAPTVEEFVGCFKNAEYVVTNS
                     FHGTAFSVIFNKNLFVEFKNKSGRNIRSEGLLKSLGINREIVDGNCRETEINWYDVNEK
                     IKNQTIISLDYLKSFVSGG"
     CDS             complement(12700..13614)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg88_12"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-30,
                     bitscore: 97.8, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEYTFSVFTPSYNRAKTLPRLYEALKKQTYRNFEWIIVDDGSAD
                     NTKETVEKFISDRPDFNITYKYQTNKGKHIATNVAAQIAKGEFFITIDSDDSVKDDALE
                     TFINEWNKIPDEDRSKYKGISCRTCNESGKTNGCPLPSERFDCSDLDLRLKYKIDGEMW
                     GMTKLEIIRANPYPCVSGLHFYPENIYWDNIGRKYITRFIDTPLRYYINDQENSLTGNA
                     YSAHRETIFVRLHFINECWDYAKSNPKFFIKQFVGLSRDGLLNGKRFSEIKKMPDTFSK
                     RALAVIFYPMGYFLYKKQSGGSR"
     CDS             complement(13638..15182)
                     /locus_tag="ctg88_13"
                     /transl_table=11
                     /translation="MKKLSTSKQMAINMVAAIVSFLIGTGINFVLAPYLVKELGSETYG
                     FIGLANNFVQYATIVTSALNSMSGRFISIEYSKGNIDKASRYFSSVLVADLIIAGVLLL
                     VSSIITFNIEFILNVPENLVDSVKILFALTFATFIISVITAIFTTAAFVKNKLYINSLR
                     DIASNTLKLLLVVILFSFFPAKVYFLAMASLASGIFLLLTNIKVKNKILPEVKMNFNLF
                     SFKLVKVLISAGIWSSIGYLSTALNRGLDLLICNLTLGAGLMGLLSIANTVPHCIDNLI
                     TTIANIFTPRFTILYAKDNTDLLVEETKFSSKIMSFLMTAPLAGFIAFGNKFYTLWQPT
                     KSPDEITIIQILSVLVCISYLFTCHTRTLSSLFTVCNKLKASVLISLVCGVLTVIIVLL
                     LIHFTPLGVYAIAGVSSVFIGLKAIVFVPLYAAHILKIKLTTYYRSIFRGWFCFAVVIT
                     MFIFINSFVHANSWMSFLLLCAASGLAGYAVSVPLIFSRKELVLIKDKIKKKFKKS"
     CDS             complement(15206..16030)
                     /locus_tag="ctg88_14"
                     /transl_table=11
                     /translation="MVYKIMYPPIPNMGDLLNKDMLEELFNIKVVRKDLKSCNLIAIGS
                     ALDHIMYSTYPRIRAKQKIEHFMNDNVHIWSTGFIRGNAELDLGLMFRHIHIHALRGRL
                     SLQRMENILGKKLDVPTGDGGLLAERWLGFYPEKKYRVGIIPHFKEQDHPVVKKLLDNY
                     ENSTLIDLKENPKKVVEKIGECEYIISSSLHGMIVADSFHIPNMHITLTNNMFGDGNKY
                     NDYLSAFDITHTPFDCSNGDMPTISEVKNNYRIDPDVVELKKEQLFNAFPKF"
ORIGIN
        1 atctttgttt ttccacagtt ttacactccc acggcataaa aacagctcct tcatttgcta
       61 ttttcttgcc atttatttta tcataaaact gtatactatg tctttgcact gttgtatact
      121 atgttactac actgcacaca tcggccgccc gccttgatga aatattttgt ttaatcatat
      181 atgttttgat gtgattataa ttgtgtattg aaccttgcac gcattgcgtg caatcgtatg
      241 cgttgcatac gaacgggcga acacggttcc ccctaaaaca tacattgcaa aaataattgg
      301 aatgttatac ttggtcaaaa tatgtatgtt gctgtgtggt tgatttggct ttgcaaccaa
      361 atcaaatggc ggtcactgac cgccgctact gtatgtacaa acaattgcta tgttatgctc
      421 gggcaacatt tgtaatttac tattaaaacc gtctgcacga acacacgaac ataaaaaatg
      481 cggtggcaca ttgccaaccg catttttatt ttacattttc aattttccac tttcaattta
      541 aaagctccgc tcggagaaca gtggcgcacc atgtttattg caccgttacc gtaatcgtta
      601 cgcttgatgt tcttttaagc acatcggtga ctgaatatgt taccttgtac ttgccttttc
      661 gggtggttac tacattgccg aaaacttcga tattcgatgt tatgtcgttg ccgcaggtgt
      721 caacggctgt tactcctgca agggcgtaaa attcgccgcc gcttttgatt gtgtaatcgt
      781 ttgcaccgct gattattggt gttgctttgg catacgggca ttttttattg ctgtctgtcg
      841 gatcccattt gttggtaaaa tcggtgattt tgattgcatc cggttttccg agagggcctg
      901 cattttctgc gtcgtcatat atgcttacat ttgtgcctgt ggggcagttg tcataaaccc
      961 actttgcatc cgaaaccgca agtcttacgc atccttgtga cgcctgttcg ccaagcttgt
     1021 tgaactcctc aagctccaaa tcttcttcgc tcattgagta gtagggaacg gagtggaaaa
     1081 gataatcgcc agaaattccg ctgatgtatc ttccgaaaac atcgcccaca agggaaagcc
     1141 attcggactt gattccgatt gtgtagtcac ccgtgattgt cgaattgtca agacctgtgg
     1201 agcaaatcat cgcccttacg gggattgtgt acttgccctt ttcgtcatat gtgtaaaccg
     1261 tcacgcagtt tgccgtgcgg ttgaccttga ttgcgtacag gttttttgcc gtgttacgct
     1321 tattgttttc aagcttgtca agatttgccg ttatacaggt tgagtagctt tgctgttttt
     1381 tcgtggttga ttttgccacc gtaacctgaa attccgactt tgatttgtct tttgaaatgg
     1441 cagaaatcag agccgtaccc tctttgagag cgtcaaccct tccgccgtca tcaacggtaa
     1501 caattttact gtccgagctt gtccatttgg taacggattt tgctttttcg gatgacagtt
     1561 caataagctt tgattcgcct acttttaatg tgagcgaatc gaccttgctc ggaaatgtca
     1621 tattttcggt tactgccgta tcgtgcgtct gcggttttgg agaattttga gaatcatttc
     1681 cgaaaattcc cgtcacaccg cataatatgc aggttgcaat gaggacaaca caaagtaaaa
     1741 gaatgaaaat tttctttttc atagattacc tatccttata gaatttaaca ttaaatggtt
     1801 acaaaatttt aacctttgta tattataact ttttttcgac aatcttgcaa gtgctatttt
     1861 aaatcggtga gaaatgtggt aaaatgtcag tcggagaatg ttttgtattt tccaaactaa
     1921 caatttatgg tgataattat ggcacatccg attaaacatt tcagaacaat aacccgtcac
     1981 aggcacaagg taattgccaa ctgtgcaagg gcaggaattc tcagacaggg attaatacac
     2041 gatttgtcaa agtattcgcc tacagaattt attccgggtg caaagtattt tcagggcacg
     2101 agaagtccca atgaaaagga aagagagctg tacggctatt cacaggcgtg gctgcatcac
     2161 aagggcagaa accgtcacca ttacgaatac tggaacgatt acaacccaaa gacaaagcag
     2221 attgaaaatg ttgaaatgcc tgtaaaatat gttatcgaaa tgttctgcga ccgagttgcc
     2281 gcaagcaaaa tctacaacgg caaaaattac acggacggcg ctccgtttac atatttctgc
     2341 agaatcagag gcaaacaccg tatgcacccc aacaccgagg ccttgcttga aaaattattg
     2401 gttatgctga gagatgaggg tgaagaaaag acatttgcat atataagaag tatgaaaaag
     2461 tgattgtttg tgcgaatccg cccgtctgaa atatagtcgc aatgctaccc ctacagaatt
     2521 gcacaaacaa aaaacggtct acacgaatag ggtacggcgg ctcgccgtaa ggagtgataa
     2581 tatgaaaacc gacagggtta taactgctat gattgaatat tttggaagtg acaagaaaag
     2641 aattcaccat tttctcaagg tttattcatt cgcaaagaca atcggtgaaa gtgaaaatct
     2701 tttgcccgac gatcaggagc ttcttgaaat ctccgcaatc gttcacgaca tcggcataaa
     2761 ggtgagcgaa gaaaagtaca attcgtctgc aggaaagtat caggaacttg aaggtcctca
     2821 cgaggctgaa aagttgcttg ctgctctcgg ctacgaaaaa acatttattg acaaagtttg
     2881 ttaccttgtg ggacaccatc acacctatgg aaatattgat actttgccgt accgaatttt
     2941 ggtagaggca gacttccttg tgaaccttta cgaggacgat tcaagccgca gtgcagcaga
     3001 gcaggcatat gacaaaatat tccgcacaaa tacgggaaaa aatctgctga aaataatgtt
     3061 cctcataccc taaaattgta ctcatttacc atagtgcttt gagtgtgaaa aagtggtgta
     3121 aaaagtatct caaaatgctt gacaacgccc ttaaaaagtg ttattttaat ggtgttggtt
     3181 atatgattat aaaagtgaat aaatgacaga atacaaggat gtatgacgat tttttcaagg
     3241 agctgacctt accgggcgtc tgcttggaat tgagtcggca tttttttgtg tcatatacaa
     3301 aattcagtat taattatcat tatcggaggt tttacagtaa tgagagaaga atggacaaat
     3361 tttgcaggtg gcaaatggga gtccgacatt gatgtcagag acttcattca gagaaactac
     3421 acaccttatg acggcgacca gtctttcctt gaaggtccta cagaagctac agacaagctc
     3481 tggggcgagc tcaaggaact ccagaaggaa gaaagagcca agggcggcgt tcttgatatg
     3541 gaaactgagg ttgtaagcgg catcacagct tacggcgctg catatcttga taaagacctt
     3601 gaaaaggttg taggtcttca gacagacaag cctctcaagc gtgcatttat gccttacggc
     3661 ggtatcaaaa tggctgagca gtcatgccag atgtatggct acactccaag ccctaaactc
     3721 cacgaaatct ttacaaaata tcacaagact cacaaccagg gtgtgttcga tatctacact
     3781 cccgagatga agcttgcccg tcacaacaag attcttacag gtcttcccga cacatacggc
     3841 agaggcagaa tcgtcggtga ctacagaaga gttgctcttt acggtattga ccgtcttatc
     3901 gaaggcaaga aagaggactt tgcagaaaca aaccgtcagg gtatgagaag aggcgacttc
     3961 cagcttcgtg aagaaatcgc tgatcagatt cgtgctctta acgatatgaa ggaaatggca
     4021 ctttcttacg gctttgatat ttcacagcct gctaagaacg ctgcagaggc agttcagtgg
     4081 ctctacttcg gctatcttgc tgctatcaag actcagaacg gcgctgcaat gagcgttggt
     4141 cgtgtatcaa cattcctcga catctacatc gagcgtgacc ttgagaacgg tacacttaca
     4201 gaatcacagg ctcaggaact cgttgaccac tttgttatga agtgccgtat ggttaagttt
     4261 gcaagaattg agtcttacaa ccagctcttc tcgggcgacc ctgtatgggc tacactcgaa
     4321 gttgcaggtc ttggcattga cggccgttct atggttacaa agaacgacta ccgtttcctc
     4381 cacacacttg agaatatggg accttcacct gagccaaacc tcacagttct ttattcttca
     4441 agacttcccg agaacttcaa gaagtatgct gctcatattt cagttacaac aagctcaatt
     4501 cagtacgaga acgatgatgt aatgcgtcct gtatggggcg atgattactc aatctgctgc
     4561 tgcgtatccg caacacagac aggtaaggaa atccagttct tcggcgcaag agctaacctt
     4621 gctaagtgcc ttctctacgc tatcaacggc ggtattgatg aaaagacaaa gatgcaggtt
     4681 ggtcctgaat atacacctat cacatcagag taccttgatt atgacgaagt tatcaagaag
     4741 tatgacacaa tgatggattg gcttgctcac ctctatgtag gcacacttaa catgattcac
     4801 tacatgcatg ataagtacta ctatgaggca gcagaaatgg ctcttatcga tacagatgta
     4861 agaagaacat ttgcaacagg tattgcaggc ttctcacatg ttgttgactc actcagcgct
     4921 attaagtacg ctaaggttaa ggttatccgt gacgaggacg gcgttgctgt tgactttgaa
     4981 acagagggtg acttcccaag atacggtaac aatgacgaga gagcagataa gattgccgtt
     5041 gatcttctca agacattcat ggctaagctc aagtattgcc acacatacag agattcagag
     5101 cctacaactt ctatccttac aatcacatca aatgttgttt acggtaaggc tacaggttca
     5161 cttcctgacg gcagaaaagc aggcgaacca ctttcacctg gtgctaaccc aagctacggt
     5221 gcagagcaga acggtcttct tgcttcactt aactctgttg ctaagcttcc ttacgagtac
     5281 gctcttgacg gtatttcaaa tactcagaca atcaacccgg gtgctctcgg acacaacgat
     5341 gacgagcgtg ttgacaacct cgtaaatgtt atggacggct actttgatca gggcgcacac
     5401 cacctcaatg taaatgtatt cggtacagaa aaactcattg acgctatgga gcatcctgag
     5461 aaggaagagt atgctaactt cacaatccgt gtatcgggtt atgctgttaa gttcatcgac
     5521 cttacaagag agcagcagct ggatgttatt gccagaacct gccacgacag aatgtgatgt
     5581 cggacaacgc tgttaaaggc tttgtacact caatagaaac ttttggctct gttgacggtc
     5641 cgggtgtgag atttgtgatt tttctgagcg gttgcgcaat gcgttgccag ttctgccaca
     5701 atcccgacac ctggaaacac gatgaaaaca ccgtggaata taccgccgac gagttgctta
     5761 ataaagcgct tgcataccgc ccctattgga aaaataaggg cggtatcaca gtaagcggag
     5821 gtgagccgct tttacagatt gactttttgc ttgatttgtt caagaaggct aaaaagcagg
     5881 gcgttaatac ctgtattgac acaagcgcca acccgtttac aaccaaagag ccgttctatt
     5941 caaagtggaa agagctaatg gaatatacgg atttgctgtt gcttgatata aagcatatcg
     6001 acaacgaaca gcacaaaatc cttacaggac agccaaacac caatattctt gaaatggcaa
     6061 gacagctttc cgatatgggc aagcccgtat ggataagaca tgttcttgtg cctgaaagaa
     6121 atgataagga cgagtatctt ttcagacttg ccgactttat ccgttcgctc aagaatgttg
     6181 agcgtgtaga ggtgcttccg tatcacacac tcggtgtgta caagtggaag gctctcggtt
     6241 atgactatcc tctcgagggc attgagcccc cgacaaaaga gcgtgttaag aatgcggaaa
     6301 tgattcttaa cggcgaaaaa acaagagatt aatttcttat ataacaacgg cagtaccgat
     6361 tttttggtac tgccgttttt gttttgattt ttatttgtta ttctgctttt gttgtttttt
     6421 cttcagcaaa attgatgaat caaaggtgta ttcaaagatt tttaagccgt ccttgttgag
     6481 aaatcgtcac cgtcggaaga atcgaccgct actcaggaac agactgttca gactgctccg
     6541 acgggtgagc ctgcaactgt cggtacaacc tccgtaaatc cgacttcggc aacaggcggt
     6601 gccgcaacat cggacagtac tccttcacag cctgataaaa acggcagcgt tcagacagga
     6661 gtgacagcaa cggctgttat gatgtttgtt gtaatttcgg gcggagtgct ttttgccctt
     6721 gcagagcgta aaaagagaat ataacacact gacagccatt tgtgcaaaga ttatcagttg
     6781 tctattgaaa aatttgtaaa tatgatataa aatagcaata agtagaaaaa tacggttttt
     6841 ccgctgattt atattaatac tgaaagaggt gccggaatgg ataaaaacaa aaaattattc
     6901 tacacaatca tcggtgcaat ctctgcactt gcggctgcca cagcagcatt tctcgcttta
     6961 aaaaagcaca gatgcgcaga acagaagctt attgaggaaa ttgacgatat tgtttccgaa
     7021 aaagagcctg aggaggctgc aaaggaagaa ccgctggcag aagttacagc cgatgagctt
     7081 gctgaggaag aataagcaac aagttgttgc acccaattcg ggtagcagta tttgcatgtg
     7141 aaaaagttaa atacccgagc ggtgctttca attaagaatt gaaagttgaa aacagataat
     7201 aatgtcggcg gtgtgccacc gcagtctatt caagaaaaca gtttaaaaaa gaaaatgcat
     7261 cagttgcccg aaaagctctg atgcattttt gttttgtgcg aagtaaccgt aagccttaat
     7321 tctctctgaa tttaagataa atggcataga cagccttttt aattttttga attggcgtaa
     7381 gcttgaaacc cttctttttc ataagactga gaatttctgc ataatagtcc ttgttctgat
     7441 gtttgagaac atagtccata tatttgttct tgtctctgta aaatttcgga atatcaaaaa
     7501 cattcttata cagttcaagt tttccgagta gcataagctc aaattgcgtt ctgacgcact
     7561 tttcacagtg accgcagttg ttctcaccgt agtaacacac attgaggtta tcatatgtaa
     7621 tcggaaattt tgaaatgaag tcaacctttt caagcctagt cttttcaagc cctgtaatgt
     7681 aaaaatcggt actttcggta ctcagcatac ttgccgtaaa tgcctcatag tgtgccgagc
     7741 cggtgtcgca ttgttttatc gaaaaactgc ttatcgggta tccagacgca tagtaatagt
     7801 ttttgaaaaa tttctgcata cacaagaccg ccgaaaagct gcaataatga tgaaccttta
     7861 catacggcag ggtaagatgt tcaccgagat ttgaattaat gtcaatcaac ggcatatcaa
     7921 agatttttgc ggattttttt gcaatttcaa gacgattttc gtacagctcg gcagattgtt
     7981 cgggtgtgta attagccgta cttctgtggg agccgacatt gaaaaaggta agatgactca
     8041 gcttttccgt tctgttttcg gaaagactgc aaattgtgtc aaatgaatcc acacctctcg
     8101 aaaatcctgt tgccgacgca tttttgcagc agtagttttc ctgtgtaagc tcttttgcag
     8161 atatcgaaat tttgttgaat aattttgaat tttttgtaag aacgggaatg aaaatttcat
     8221 taagctgaaa acacagttgc ttcgacatct ttgcttctgc cgaaatattc agactgttgt
     8281 tcattgcata cggcaacagt gcaacaacga atgcgtcggc actttcggtc agatagtcag
     8341 catactttgt atcaacatca aaccagagag tgtaggaagg ctttccgttt tcgctgattt
     8401 ttgaacagag tctggcacga ttatcaagtt tttcaatttt cggtttgccg ataatcaatg
     8461 tttccatact tttaccctca aattaatctc tgaaaaacaa atctcttgtg taaacctttt
     8521 cttttacaca gtcaagaacg gagctgtatc tgtttgcaac gattacatcc gattttgtga
     8581 cgaacttttc aaagtcgttt tcaacgccaa agccctcgaa taaatcgact ttaagtgtcg
     8641 gttcgtagat aattaactcg atgccgttat ttttcaaaag ctccataacg ctctgaattg
     8701 agctttgtct gaagttatcg gaatttgact tcattgtaag gcggtaaatt ccgacagctt
     8761 ttggattttt attcattatc tgtgatgtaa taaattcttt tcttgtcttg ttagatgtta
     8821 caacagcgct gattatgtca ttcggaacat ccgaaaaatt ggccttgagc tgttttgtat
     8881 cctttggcag acagtaaccg ccgtagccaa aggacggatt gttgtagtga tttccgattc
     8941 tcggatcaag acacacaccg tcaatgatac ttttagtgtt aaggttcttc atttcggcat
     9001 atgtgtcaag ctcgttgaaa aagctgacac gcattgcaag gtatgtattt gcaaaaagct
     9061 ttaccgcctc tgcctctgtg tagtccataa agagagtgtc tatgttttcc ttaattgcac
     9121 agtctgcaag tgctgttgca aaagtctcgg cagatttttt cagttcttca tttgccatat
     9181 caacaccgac aatgattctt gacggataga ggttatcata gagagccttg ccctcacgca
     9241 aaaattcggg actgaaaagg atttttgtgt atttgtattt ttcaataaca ctttttgtgt
     9301 atccaaccgg tatagtggat ttgataacta taaccgcatt tgggttgcat tcaattacaa
     9361 gcttaattac agcctcaacg gacgatgtat caaaaaagtg tctttcgtca tcgtaattgg
     9421 taggagtaga gataattaca aaatcagcat ttttgtacgc agattttgca tcgacggttg
     9481 caaccaaatt taattttttg tcagcaagat attcttcgat ttccctgtcg gcaatcggag
     9541 atttcttttc attgattaac tttaccttgc tttcaactac atcaacagcg gttacctcgt
     9601 gtttctgcga aagaagtaca gcgtttgaaa gacccacata ccctgtcccg gcaattgcta
     9661 ttttcatttg gtttcacctg attacttttt taataatttt tttgcctttt gaatctgtga
     9721 cggactgaga attgactttg ctttttccat catcttgagc ttcattccgc caaatttcat
     9781 tctgttgtca tgaaaaagcc tgttaataag ctttgcgtcc tcttccatat cggtgaaaat
     9841 ctcaacaaaa atcggtcggt cggattcttc tgcgagtgtg ggaataatgt tgtcaacttc
     9901 ttccttggtt gttgcgctgt aatagtcata tccgagtgat tcaatccagc cctttgcgcc
     9961 cttgtgatgt tcggcgcaga tgtactgatt gattgtagga atcttttcct tgcccataaa
    10021 gaagtgaaat tctgaaccgc cgccgttgtt gagaagaata attctcgcat tgttcttgat
    10081 tcctctgatg cctgcggagt tcatatcata gaagaaactg aggtcgccca caacgcaaaa
    10141 ggcaagctcg tctgttgccg atgcctgtcc gaaaaacgaa gacatacagc cgtcaatacc
    10201 cagagcgccg atattgctgt aaaccttgac attcggtttc aaatcgaaga actgcatagt
    10261 tcttgtactg ctgagaattg caaggtgcag aacagaacgg tcgggaataa tttcagcaag
    10321 ctttttggca acatacatat ttgagaacgg aagattgctt gaataatcaa gcattttgat
    10381 atcgtcattc cacatattgt agtatgtcat atcatttttt gaattctgcg gtgcgttctc
    10441 tgcaaagcag ttaaagaaat actgcggtgt acattcaaat acatctgtca gcttgtcgga
    10501 aaaatctctg attcttcccg cagtatcaat ttgccagtga acaaattttt ccttgtgagc
    10561 cttaatcata ggcttgagtt tatatgaagc aatattgttg ccgaacgaaa taataagatc
    10621 ggggcataac tcgccgaaca ttccctgcat tgagcattct gacaaaggat aggtcataag
    10681 gcagcccttg cacttgaggt ttgacatatg ctcaaccgat ataaggcaat tgtatttctc
    10741 aaagaacttc tcgacgcacg ctctgtcatc ttccgagaaa cagttgttct gaccggcaat
    10801 gacaagaatt ttcttatatt ttgaaagcct ttctgcatat tcacgccact tctcggaggg
    10861 catatcggga gaaattctgt tgattttcct aacctgagga agattttcac aatcatatac
    10921 agccgagttt tcaacaatcg gaatattgat atgcacaggt cctgttccgt gatggtcaag
    10981 ctccgaaaga gcctcgttaa taagtctttc gcagtaccat ctgtcatttc cgccacgcac
    11041 aacgggaaga ttaacggatt tttttgtaac cgattcaaaa atattgacct gctgggtttt
    11101 ctgcagcata agctgattta atctgtacgg gtctttgtca gcggtaattg cgacaatcgg
    11161 aacatcctga taaaatgcct ctgtcatacc cggaagatag ttgcttacag ccgtacccga
    11221 ggtacagata caggcaacgg gggattttgt ctgctgtgca agtccgatgc cgtaatacac
    11281 ggcacttctc tcgtcaacga ccgaatgaca ctcaaaaaaa tcgtcatttt caagtgaatg
    11341 aattatagga atatcactgc ctccgggaga aagcaccaat ttgttgatat tatatttttt
    11401 cagaagtgca gtgagcaact gaatgctttt tattgtagaa tacatacgct ttcctccgct
    11461 ttagtttttg ataattccgg aaccgcctgt aatcagagcg gttttgccgt caagaatatt
    11521 gttgttctcc ttctgcacat acacgggaac aacatttttt gctttaaagg ttttgattat
    11581 gccctgtctg acttttttta gtgtattttt aagactcatt ttaaccaccg ctgacaaagg
    11641 atttaagata atccaaagat attattgtct ggttcttgat tttttcgttc acatcgtacc
    11701 agtttatttc ggtttctcgg cagtttccgt caacaatttc acggttgatt ccaagacttt
    11761 tcaaaagacc ttcggagcgg atgtttcttc cgcttttgtt cttgaattca acaaaaagat
    11821 tcttgttgaa aataacagaa aacgctgttc cgtgaaacga gtttgtaaca acatattcgg
    11881 catttttgaa acagccgaca aattcctcaa cagtaggtgc aacaatataa tttataccgt
    11941 gacttacagg gtgaggtgca tcgtttatgc agtaaacggg aaggttcttt tcttttgaca
    12001 gtttaatggc aaaatccaca agcgaaactg ccggattagc cgtaaaaatg aggatatacg
    12061 gtttgtcaat ttttgaaacg gcaatctttt tccattcgtc tgccgaaatc agcagggtag
    12121 gatcaagatg agtttcggcg gttctgcccg tgagttcttt tacaagcttt tctccgctcg
    12181 gttcacgaac tgagaacttc tgaaaaccgt tcagcctttt tttatattca tcaataaatt
    12241 catcgggcaa tgtcggaacg gcaaagcttg ccgcatatga atacttctgt ttgtcatcgg
    12301 caaatgtcag aaaataagcg ggatcaaaac cgacgcatct cggactccat acctgatcgc
    12361 ttcccgaaat gaacaagtca taatcgtttt taagctctct gatattttgc ggagtatacg
    12421 actttttact ctttacaaga tagttattga aaaacgactt aaaagcgtct ctgcgttttg
    12481 ctcttcttct taccatgaca cagctttttg caaaggattt cagaaggtcg tttttataaa
    12541 tgcgaaaggg tttgtagtcg gctgtgattt tcggacagat atagtcaaca atttcacact
    12601 ccgcaccgag cgatgaaacg gttttttgca acgcatagct ctgaagcaca gcgccgtagt
    12661 tcaatgcacg gtgaaatgtt acaatgccta cctttttcat tatctgcttc cccctgattg
    12721 ttttttgtac aaaaaatatc ccatgggata aaatatgacc gcaagagccc tctttgaaaa
    12781 tgtgtcgggc atctttttta tttcggaaaa tcttttaccg ttgagtaagc cgtcacggga
    12841 aagtcccaca aattgtttga taaagaactt aggattgctc tttgcgtaat cccaacattc
    12901 gtttataaag tggagtctta cgaaaatagt ttccctgtga gccgagtaag cgttacccgt
    12961 caaagaattt tcctgatcgt ttatgtaata tcgcaacggt gtgtcaataa aacgggttat
    13021 atattttctt ccgatattgt cccaatagat attttcggga taaaaatgaa gtcccgaaac
    13081 acacggataa gggttggctc tgattatttc aagttttgtc attccccaca tctcaccgtc
    13141 aattttatac ttcaatctca ggtcaaggtc ggaacagtca aatcgttctg acggcagagg
    13201 acaaccgttt gttttgccgc tttcgttaca ggtgcggcac gaaattccct tgtattttga
    13261 tctgtcttca tcgggaattt tgttccattc gtttataaat gtttcaaggg catcgtcttt
    13321 tacgctgtca tcggagtcaa tcgttataaa gaattcaccc tttgcaatct gtgccgcaac
    13381 atttgttgca atgtgttttc ctttgttggt ctgatattta taggttatgt taaagtcagg
    13441 tctgtcgctg atgaatttct caaccgtttc ttttgtgttg tcggctgaac cgtcatcaac
    13501 aattatccat tcaaaatttc tgtatgtctg ttttttcagc gcctcatata atctgggcag
    13561 agtttttgcc ctgttatatg acggtgtaaa aacggaaaaa gtatattcag tcattgcaac
    13621 ctcaaaatga taataattta gcttttctta aacttcttct taattttatc cttgataaga
    13681 acgagttctt ttcttgagaa aatgagcgga acggaaacgg catatcctgc cagtccgctt
    13741 gctgcacaga gaagaaggaa tgacatccag ctgtttgcgt gtacaaagct gttgataaag
    13801 atgaacatgg tgataacaac agcaaagcag aaccatcccc tgaaaataga cctgtaatat
    13861 gttgtaagct ttattttcaa aatatgtgcg gcgtacaacg gaacaaatac tatcgcttta
    13921 agaccgataa aaacagagct gacgcctgca atagcataaa caccgagcgg tgtaaagtgt
    13981 atgagcagta aaacgataat aaccgtaaga acaccgcaca caagcgagat aagaacggag
    14041 gccttgagct tgttgcatac ggtgaaaagg ctagaaagag ttcttgtgtg acaggtaaat
    14101 aggtatgaaa tacatacaag caccgacaaa atctgaatta tggtaatttc gtccggagat
    14161 ttggtcggct gccacaatgt atagaacttg ttgccaaacg caataaatcc cgcaagaggt
    14221 gcagtcatga gaaaactcat aatctttgac gaaaactttg tttcttcaac aagtaagtcc
    14281 gtgttgtcct ttgcataaag gattgtaaat ctgggagtga atatatttgc aatggttgta
    14341 ataaggttat caatgcagtg cggaacggtg tttgcaatcg acaaaagtcc catgagtccc
    14401 gctccgagag tcaggttaca gattaacagg tcaagacctc tgttcagagc tgtgctgaga
    14461 taaccgattg acgaccaaat tcctgcggaa atcagaactt ttaccagctt gaaactgaaa
    14521 aggttgaagt tcatctttac ttccggcaga attttattct tgactttgat attggtaagc
    14581 aaaagaaaaa ttccgcttgc aagtgacgcc atagcgagaa aatatacttt tgcgggaaaa
    14641 aacgagaaca aaattactac aagcaagagc ttgagcgtat ttgacgcaat atcacggagg
    14701 gaattgatat acagcttgtt ttttacaaat gccgcagtag taaatattgc cgtgataacg
    14761 ctgattataa atgttgcaaa agtgagcgca aacaatatct ttacgctgtc aacaagattt
    14821 tcgggaacat tcagtataaa ttcaatgttg aatgtaataa ttgacgaaac caaaagtaaa
    14881 acgccggcaa taatcaggtc ggcaaccaga accgagctga aatatcttga tgccttgtca
    14941 atgtttcctt tgctgtattc aattgaaata aatctgcccg acattgagtt gagagcagat
    15001 gttacaatgg tggcatactg gacaaagttg tttgcaagtc cgataaatcc gtaggtttca
    15061 gaaccgagtt cctttacaag atagggtgca agaacaaagt taattcctgt tcctatcaag
    15121 aaagacacta tggcggcaac catatttatt gccatttgtt tacttgttga taattttttc
    15181 ataatatgac cttagtttta actgattaaa attttggaaa agcattgaag agctgttctt
    15241 tcttcagttc aacaacatcc ggatcgattc tgtaattatt tttcacctcg ctgattgtag
    15301 gcatatcgcc gtttgaacaa tcaaagggtg tgtgtgtaat gtcaaaggcg gagaggtaat
    15361 cattgtactt gtttccgtca ccgaacatat tgtttgtaag ggttatgtgc atattgggaa
    15421 tgtggaaact gtcggcaaca atcataccgt gaaggctgct tgaaataatg tattcgcact
    15481 cgcctatttt ttcgacaacc ttttttgggt tttccttcag gtcaataagc gttgaatttt
    15541 cgtagttatc aagaagtttt ttcacaacag ggtgatcctg ttccttaaag tgcgggataa
    15601 ttccgacacg atactttttt tcgggataaa atccaagcca cctttcggca agaagtcctc
    15661 cgtcacctgt cggcacatca agctttttgc cgagaatatt ttccattctc tgcaatgaaa
    15721 gtctgcccct cagagcgtgt atatgtatat gtctgaacat cagccccaaa tcaagctcgg
    15781 cattgcctcg gataaagccc gtactccata tgtggacatt atcattcata aaatgctcaa
    15841 ttttctgctt tgctctgatc ctcggatatg ttgagtacat tatgtggtca agtgcagaac
    15901 cgattgcaat caggttacag cttttaaggt cttttcttac aaccttgatg ttaaacagtt
    15961 cttcaagcat atctttatta agaagatctc ccatattcgg aatcggggga tacattatct
    16021 tatataccat tgtattttct ccgttgtatt atttgcgccg tgagcagaag ctctgattaa
    16081 gagatataaa tatcggattt gtcttgcata tgtatatcag cgaataagta ataagcatcc
    16141 atatcgatgt tgttgcccat ggttcggtgg aaatcagaag ttttggaagt gttacgcaca
    16201 caagcgtaca gcacaacgca aattctgact tatctttgat tcttgtgcat acaacctttg
    16261 ccgtcagcga aaggcttgaa tataccggaa taagtccgaa tacaattccg ccttcaaaga
    16321 ggtattggta ga
//
