LOCUS       c00117_gnlPro..        13282 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JBBMAOED_117.
ACCESSION   c00117_gnlPro..
VERSION     c00117_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 01:12:57
            Original ID  :: gnl|Prokka|JBBMAOED_117
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13282
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13282
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[589:5601]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      590..5601
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..13282
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13282
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(590..1381)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1020:4Fe-4S binding domain (Score: 31.8; E-value:
                     2.7e-10)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_1"
                     /sec_met_domain="Fer4_7 (E-value: 6.3e-11, bitscore: 32.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.1e-08, bitscore: 22.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1e-16, bitscore: 49.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.2e-05, bitscore: 15.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIGAIIAATVLVAAVGLFIGVFLGVAGKKFAVEVDEKEVAVREA
                     LPGNNCGGCGYPGCDGLAAAIAKGEAPVNGCPVGGEPVGKVIAAIMGQEVVETARQVAY
                     VKCAGTCEKTKDNYEYTGVEDCEMMAFIPGGGAKSCTYGCLGFGSCVKACPFGAIDVVN
                     GVAVVDKEACKACGKCVAKCPKHLIELVPYEQTTFVQCSSHAKGKAVTSACEVGCIGCK
                     KCEKTCPNGAITVDNFCAHIDYSKCTNCGACKEVCPRHIIQ"
     CDS             complement(1395..1970)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_2"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.8e-63, bitscore:
                     202.5, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKELLIILVSSAIVNNVVLSQFLGLCPFLGVSKSVETAAGMGGAI
                     IFVITLSSFVTGIIYNAILVPTNLTYLQTIVFILLIAALVQFVEMFLKKTMPSLYQALG
                     VYLPLITTNCAVLGVALTNVQKEYNVLQGTVNGFATAVGFTISIVLMAGIREKIAYNDI
                     PKSFQGFPTVLLTAGLMAIAFFGFSGLI"
     CDS             complement(1977..2687)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_3"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.3e-72, bitscore:
                     232.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPNTPAERLYNGIIKENPTFVLMLGMCPTLAITTSATNGIGMGL
                     TTTVILAASNLMISLLRNFIPDRVRMPAFIVVVASFVTVVQLLLQGFIPSLYDSLGIYI
                     PLIVVNCIILGRAEAYASKNKPIASLFDGIGMGLGFTLSITCIGAVRELIGAGSLFGHQ
                     ILPLADAAAGKAGYEPITIFILAPGAFFVLAALSALQNKFKIGAAKRGIDPSNPDCGGS
                     CAACGNTMCKGKRG"
     CDS             complement(2687..3295)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_4"
                     /sec_met_domain="FMN_bind (E-value: 7.4e-21, bitscore:
                     64.1, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNRIIKDTIAITVITLVAGLALGVVQDITADPIAKQEAQAKQDA
                     YKAVFADADSFETVDVDADAMQSYLDENGYAAQSIDETMLAKDASGNELGYAFTVTTSE
                     GYGGDIQFAMGIQDDGTLNGISILSIGETAGLGMRANTDAFKDQFKDKNVDKFEYTKTG
                     ATADDQIDALSGATITTNAMTNGVNAGLCAFQYEKGGNQ"
     CDS             complement(3292..4269)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_5"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 3.5e-121,
                     bitscore: 393.4, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQMLHVSSNPHVRDKMTTSKIMQLVALALLPTTLFGIYNFGLRA
                     LLVVVITVASSVFFEWIYDKLMHKKNTITDFSAVVTGLLLALNMPASIPLWMPVLGSAF
                     AIIVVKQLFGGLGQNFMNPALAGRCFLMISFAGKMTDFAVSDSFRGVVDTVSGATPLAA
                     LKQNGFTDSSVSVLHMFIGDIQGTIGETSALAILIGAAILLVFKVIDLKIPLTYIGSFA
                     VFVILYMLGTGKGFDVNYLFSHIFGGGLMLGAWFMATDYVTTPITPRGQYVYGVCLGVL
                     TAVFRLFGGSAEGVSYAIIFCNLLVPMIERVTRHPAFGKGGKKA"
     CDS             complement(4285..5601)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_6"
                     /sec_met_domain="SLBB (E-value: 6e-18, bitscore: 54.0,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 4e-49, bitscore:
                     155.9, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.6e-42, bitscore: 133.1,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.8e-05, bitscore: 14.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGILTFKGGVHPYDGKELSKNSPVVKYLPKGDMVYPLSQHIGAPA
                     AAIVQKGDHVLAGQKIADAAGFVSSPIHSSVSGTVKGIEPRLTATGSMVNSIIIENDQQ
                     YESVEFTPARLEDLSKEEILARIKEGGVVGMGGAGFPTQVKLAPKEPDKIDHILVNGAE
                     CEPYLTSDYRRMLDDSEKLIEGLRVMLKLFDNAKGYICIEDNKPDCIAKLKEMVKDIPR
                     IEVAELMTKYPQGGERFLIKAVTDREINSAMLPADAGCVVDNVDTVIAVYEAVILGKPV
                     MDRIVTVTGQGIKNPQNFDVLSGTDMAELIEAAGGLTDNVSKVISGGPMMGFAMYDTHV
                     PCIKTSSACLCLEKDDVADAEQTACINCGRCVGVCPGHVIPARLATFAEHGDMKSFQKF
                     DGMECCECGCCSYICPAKRPLTQMIKSMRKMVLASRKKK"
     CDS             5786..6811
                     /locus_tag="ctg117_7"
                     /transl_table=11
                     /translation="MIVKKMPILQGFPDFETVKFFTGKFFQKYNFTPVFYDIETTGLSR
                     NSTYLYLIGAVGIEDETWYFYQWMAENASEEETILRIFSQFLQQYNLMISYNGERFDQP
                     YLEARYEKYGIPSPFTGKQSLDLYLILKPLKSLLKLPAMQQPCMEEFLGIKDRIYDNGK
                     ECIKLYKDFLKKRDAFTADEILGHNLEDVLGLGRIFDMLGYLCIYDGDYEVTYSEFDGD
                     NLILKLKLPCTLPQEFSNGNTDFYLTGKDEEINLIIKTTDGKLKQYYADYKDYYYLPEE
                     DTVIPKSLGSGIDRKHRKAATRNTCYTWFTCSDAFLSSPVQQKQYLTYTLSCLIGTLER
                     V"
     CDS             complement(6826..7473)
                     /locus_tag="ctg117_8"
                     /transl_table=11
                     /translation="MQKLYRININHFEDPLKNERLLDLVGIRRREKVIRYRMPDDRKRS
                     LGAGIIIRKILDENGLTESCLRYSDNEKPVVDGLFFNVSHAGDYVVGVLSDCEVGCDIE
                     KNANAPLEVAEHYFYHSELAYIKAAKNKDKAFFTLWTLKESYMKMTGRGMSLPLDSFEV
                     VPTADGFVLGKSSERPCFFETMEFDGYIFSVSSERAFSLHNPLEIAFDDIYI"
     CDS             complement(7485..7787)
                     /locus_tag="ctg117_9"
                     /transl_table=11
                     /translation="MEIITKTEGNKATMEISGWLDTQTAPQLGEALSGLEDSITSLVFD
                     FTNLEYISSAGLRQVIVAYKKMAQKDGFKIINVSDEVYDVFSLTGFDSKIDIQKK"
     CDS             complement(7807..13281)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 292.2; E-value:
                     1.8e-89)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg117_10"
                     /sec_met_domain="AMP-binding (E-value: 2.9e-90, bitscore:
                     292.2, seeds: 145, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding_C (E-value: 6.8e-11, bitscore:
                     32.6, seeds: 272, tool: rule-based-clusters)"
                     /sec_met_domain="Epimerase (E-value: 5.1e-22, bitscore:
                     67.8, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="FILLYTSGSTGVPKGCMLEYGNITAFCHWFKRYYGIDSECRIAAY
                     ASFGFDACMMDIYGAITNGAQLHIIPEEIRLDFIGLQRYFEENGITHSFMTTQVGRQFA
                     LEMDCKSLRYLSVGGEKLVPCEPPKDYKFINAYGPTEATIFTTVFEVDKYYPNVPIGKA
                     LDNVKLYITDKLGHMLPPGACGELMITGWQVSRGYLNKPEKTAEVYTKNLYDDTPGYEV
                     MYHSGDVARFLPDGNIQIIGRKDSQVKIRGFRIELSEVEEVIRRYEGIRDATVVAFDDP
                     NGGKYIAAYVVSDSTVDINALNDFIKETKPAYMVPAVTMQIDKIPLNQNQKVNKKALPL
                     PEKKAAEIIKPENEVQQILFDCIAEVLGYTDFGITTDIYEAGLTSITAIKLNILISKAF
                     DIVIKTSDIKNHPTIRMMEEFVKTAGKESKREVQESYPLTNTQEGIFIECTANMGSTIY
                     NIPYLLKLDNKVDLDRLAEAIDSTVEAHPYLKTRLFMDDNGNVLQKRNDGLSYKTPILN
                     GMNRDTLVRPYMLFNEQLFRFEIYRTCDGNYLFLDLHHIVADGTSLAIIINDINRAYSG
                     EKLEPEGYTSYDLALDNRDALAGDIYKNAENYYKSVFEHAGGSISFYPDKNGAAPTAEL
                     YHRETRSISVQDVKEFCKKHGITENVFFISAFGITLGKYNFKKDAVFTTIYHGRNDSRL
                     SETVGMLVKTLPVFCDFSGTAKDCLSGVQKQLIDSMNNDIYPFSQISHEFDIKADAMVI
                     YQGDNFAFDTIGGEYAQEEPVSLNMAKAPVSVSISIEKNRFVFEIEYRGDMYHEETIRY
                     LADNLETTAEGILRECDPADIRLMFEEKTQMEDIPEHAGKTFIDLFKEMAARYPDRPAV
                     RDDSGDFTYRELDRMSDYIAQKLTENGFGPEQAAGILCGRTKEYTVAYVGVMKAGGAYV
                     PLDPEYPQSRIEYMLKDSGARNLLVIDQYQNLVEFYDGNVISLDSVPDEAEDFELSAEL
                     ISPKPENLAYMIYTSGSTGKPKGVMIEHRNLLNLIEYITLSRNTSPDDIVAEFASFCFD
                     ASVIDLFAPLTAGAVLYILPESIRKDAIAISRYIKEKEITTVTFPTQMGELVTELLEDA
                     PALKFVTLGGEKFKHYRNRTYQMINGYGPTENTVSSTEFLVDRQYDNIPIGKSQRNVRS
                     YIVDENLNRLPVGASGELCHAGRQIARGYHNLPEKTASVFVENPFAVCEQESRLYRTGD
                     MVRMKGDGNIEYIGRIDSQVKIRGYRVELGEIEGALLKHELVKNAAVTVIEKGGNKYIT
                     AYYTGEAIPEDELKTFLEPLIPDYMMPSFFVSIEEMPVTPGGKIDKKALPMPEVTTNTA
                     SDVEPVTAAQRALCEIFEKALGIERVGIEDNFFELGGSSLTASKVAVMCLSKNISLVYA
                     DIFKYPTVRELAALVDDDGVTEAAQSKNEFSDYNYNRIQNVISANTEENADRITKEKLG
                     DIMVTGATGFLGIHVLKAFIDNYDGKVYCLVRKGKYESSEKRMMNMLMYYFDDPYKELF
                     ESRIICVDGDITSKEQVTGFSEYKFSTIINCAACVKHFAADDVLERINVQGVENLIDFC
                     KNNGRRLIQISTVSVAGEGSDGVPPMSRVFCENDLYIGQNITNEYIRTKFLAERAVLEA
                     VSEGLDGKVVRVGNLMSRNSDGEFQINFITNGFLRSLRGYAAVGKFPMGGMHEVAEFSP
                     IDSTALAVLRLAQTDRRFTVFHACNSHHIYMADLIYAMRSYGFRIDIVRDEEFEAAVKE
                     FAKTGQDSDAVSGLIAYTSHNENEIYTIDYSNRFTAQVLYRLDYKWPVTDDRYLENAIA
                     ALDRLTFFD"
ORIGIN
        1 gaacaaacgc aatcatgata catcctccgt cccacagcaa tcctctccaa catcacatct
       61 gagcagatca ccacaaaatt catcacttcc gattcataat accacatccc acaccataac
      121 gcaaacatat attcgcgtac actgttcgca caccttgcga aacagttact gttcactccg
      181 ttcacagtaa tttagccaaa attcattcca gattgcctgc ggcaatggaa ttttggcttg
      241 tatgtctcgg gattttggca tattcatgcc aaaacacctc gcgggatagt ggtgtgtgaa
      301 cagtaacgcg aaacaaccag taaacagcgc ggggcattat ttcggtttgg gtgaattttg
      361 caggaagcgt agtaactctt agttccggga aatctgcgtt attcgaaaaa tgctcactgt
      421 ctgagccgct tcgcggcgag tttgagcatt tttcgaatgc ttttagcaga ttttccgaaa
      481 cttagagttc ctagcttccg aaactgaacc caaaccgaaa taatgctccg cgcgtccctt
      541 aatcgaaaaa aagaaccgcc atgccaccgc acagcagttc ttcctcccat tactgaataa
      601 tatgtctcgg acaaacctct ttacaagccc cacaattcgt acacttacta taatcaatat
      661 gcgcacagaa attatcaacc gtaatcgccc cattcgggca agtcttctca cacttcttac
      721 atccgataca gccaacctca cacgcagaag taacagcctt acctttcgca tgagaactac
      781 actgcacaaa cgtagtctgc tcatagggca caagctcgat cagatgcttc ggacacttgg
      841 caacacactt accgcaggcc ttacaagcct ccttatcaac aaccgccaca ccgttcacaa
      901 catcaatcgc cccaaacgga caggccttca cgcagcttcc aaaaccaagg catccataag
      961 tacaggactt cgcaccacca ccgggaatga aagccatcat ctcacagtct tccacacctg
     1021 tatactcata attatccttc gtcttctcac aggtacccgc acacttcaca tacgccacct
     1081 gacgggcagt ctccacaact tcctgtccca tgatcgctgc gattactttt ccgacaggct
     1141 caccgcctac cggacatccg tttacaggtg cctcaccttt ggcgatcgct gctgccagac
     1201 catcacagcc gggataacca cagccaccgc agttattacc gggaagcgcc tcacgaacag
     1261 caacttcctt ctcatccact tccacagcaa acttcttacc ggcaacacca aggaaaacac
     1321 cgataaaaag acctactgcc gcaaccagta cagttgccgc gataattgct cctatattca
     1381 taccagtccc ctccttaaat cagtcctgaa aatccgaaga aggcaattgc catcagtccg
     1441 gctgtcagca gaactgtagg gaatccctgg aaggattttg gaatgtcatt gtatgcgatt
     1501 ttctcacgga taccagccat cagcacgatg gaaatagtaa agcccactgc tgttgcaaat
     1561 ccgttcactg ttccctgaag aacattatac tctttctgca cgtttgtaag ggcaacacca
     1621 agaaccgcac agtttgttgt gatcagtgga agatacacac caagtgcctg atacagggaa
     1681 ggcattgtct tcttaaggaa catctctaca aactgtacca gcgccgcgat cagcaggatg
     1741 aatacgatag tctgcagata agtcaggttc gtaggaacca ggatagcatt gtaaataata
     1801 cctgtcacaa aagatgacag tgtaataacg aagatgatcg caccgcccat gccggctgct
     1861 gtctcaacac tcttggaaac accaaggaaa ggacagaggc caaggaactg gctgaggact
     1921 acgttattta caatcgctga gcttacaagt atgatcaaaa gttctttcat aatccattac
     1981 cccctttttc ccttacacat ggtattgcca caggctgcac agcttccgcc gcaatcagga
     2041 ttacttggat caatgccacg tttggctgca ccgattttga atttgttctg taatgcagaa
     2101 agcgctgcca gaacaaagaa tgctccgggt gccaggataa agattgtgat cggttcataa
     2161 ccagccttac ctgctgcagc atctgccaga ggaagaatct gatgtccgaa cagagaacct
     2221 gcgccgatca gctcacgtac tgcaccgata caggtgatac ttaaggtaaa tccaaggccc
     2281 ataccaatac catcaaacag agaggcaatc ggtttattct tggatgcata tgcttctgca
     2341 cgtccaagga tgatacagtt aactacgatc agaggaatat agattccaag ggagtcatac
     2401 agacttggga taaatccctg taaaagaagc tgtacaactg ttacaaagga agcaacaact
     2461 acgataaatg caggcatacg cactctgtcc ggaataaagt ttctcagaag agagatcatt
     2521 aagttggatg ctgcaaggat cactgttgta gtaagtccca ttccgatacc attggttgca
     2581 gatgtggtga tagccagtgt aggacacata ccaagcatca gtacaaaggt aggattttct
     2641 ttgatgattc cgttatataa acgttcagca ggtgtgtttg gtttcatcac tgatttcccc
     2701 ctttctcata ctggaatgca cataatccgg cattaacacc gtttgtcatg gcattcgttg
     2761 taatagtggc accacttaac gcatcgatct gatcatccgc tgtggcaccg gtctttgtat
     2821 attcaaattt gtctacgttc ttatctttga actgatcctt aaatgcatct gtgtttgctc
     2881 tcataccaag acctgcggtc tcaccgatgg aaagaatgga aattccattt aaggtaccgt
     2941 catcctggat acccattgca aactggatat ctccgccgta accctcggaa gtggttactg
     3001 taaatgcata tcccagttca ttgcctgaag catctttggc aagcatagtc tcatctatgg
     3061 actgtgccgc atatccgttc tcatccagat aagactgcat ggcatccgca tccacatcca
     3121 ctgtctcaaa gctgtccgca tctgcaaata ctgccttata cgcatcctgt ttcgcctgtg
     3181 cttcctgctt tgcaatagga tctgctgtaa tatcctggac tacaccaagg gcaagtcctg
     3241 ccaccagtgt gatcactgta atggctatgg tatctttgat aattctgtta ctcatgcctt
     3301 tttgccccct ttcccaaatg ccgggtgacg agtcacacgt tcgatcatcg gaactaacag
     3361 gttgcagaaa atgatcgcat aggatacgcc ctctgcggaa ccgccgaaga gacggaagac
     3421 cgcagtcagt acaccaagac agacaccgta tacatactgt cctcttggtg tgatcggtgt
     3481 tgtgacatag tctgtagcca taaaccatgc accaagcata agaccaccgc cgaagatgtg
     3541 gctgaacaga tagttcacgt caaatccctt gcctgttcca agcatgtaaa ggattacaaa
     3601 tactgcgaaa cttccaatat aggtaagcgg aatcttcaga tcgatcacct tgaaaaccag
     3661 aaggattgct gctccgatca ggatcgcaag ggcagaagtc tcaccgatag ttccctggat
     3721 atcaccgata aacatatgta atacagatac agaactgtct gtaaatccat tctgtttcag
     3781 agctgccaga ggagttgcac cggatacagt atctaccaca cctctgaagc tgtcgcttac
     3841 tgcgaagtct gtcatctttc ctgcgaaaga gatcatcagg aaacatcttc ctgcaagtgc
     3901 cgggttcatg aagttctgtc ccagaccacc gaagagctgt tttacaacga tgatcgcaaa
     3961 tgcactgcca agtacaggca tccagagcgg aattgatgca ggcatattta atgcaagtaa
     4021 taaacctgta acaactgcac tgaagtctgt aattgtgttc ttcttatgca tcagcttgtc
     4081 ataaatccac tcaaagaata cactggaagc gacggtgatc actactacca gtaaggcacg
     4141 aaggccaaaa ttataaattc caaacagtgt ggtcggcaga agcgccagtg ccacaagctg
     4201 catgattttg cttgttgtca tcttatcccg gacatgggga ttggatgata catgtaacat
     4261 ctgatccatt acgatgtccc ccttttactt tttcttacgg cttgccagaa ccatcttacg
     4321 catagatttg atcatctggg tcagcggacg cttggcaggg cagatataac tgcagcagcc
     4381 acattcgcag cactccatac catcaaattt ctggaagctc ttcatgtcac catgctctgc
     4441 aaaggttgca agtcttgcag gaatgacatg gccgggacag actcctacac atctgccgca
     4501 gttaatgcat gcagtctgtt cggcatctgc cacatcatcc ttctctaggc agagacatgc
     4561 ggagcttgtc ttaatacatg gtacatgagt gtcatacatg gcaaatccca tcataggacc
     4621 acctgaaatt actttggata cattgtctgt cagtccgccg gcagcttcta taagctctgc
     4681 catatctgtt ccggaaagga catcaaagtt ctgcggattc ttaatcccct gtcctgttac
     4741 tgtcacgata cggtccataa caggttttcc aaggataacg gcttcataaa cagcaattac
     4801 ggtatctacg ttgtcaacta cgcatcctgc atctgccgga agcatggcag agttgatctc
     4861 tctgtctgtg acagccttga tcaggaaacg ctcaccaccc tgtgggtact tggtcatcag
     4921 ctctgctact tcaatacgtg gaatatcttt taccatttct ttcagtttcg caatacagtc
     4981 aggcttgtta tcctcaatac agatgtatcc cttcgcattg tcaaagagct tcagcataac
     5041 tcttaagccc tcgatcagct tctcagagtc atccagcatt cttctgtagt cactggtaag
     5101 atagggttca cactcggcac cgtttacaag gatatgatcg atcttgtccg gttcctttgg
     5161 cgcaagcttt acctgtgtgg ggaatccggc gccgcccatt cccacaactc cgccttcttt
     5221 aattctcgcc agaatttcct ctttcgaaag atcttccaga cgtgcaggag taaattccac
     5281 actttcatac tgctggtcat tctcaatgat aatggaattg accatagaac ctgttgctgt
     5341 caggcgcggt tcgattcctt ttaccgtacc ggaaacagac gaatggatcg gtgatgagac
     5401 aaaccccgca gcatctgcga tcttctgtcc tgcgagcaca tggtctccct tctgaactat
     5461 cgctgcagcc ggagcaccga tatgctggga aagaggatat accatatctc cctttggcag
     5521 atatttcact accggactgt tcttggataa ttcttttccg tcataaggat gaacaccacc
     5581 cttaaaggtt aaaattccca tttcgttccc tccttttata ttaagcacca ccaaagtgct
     5641 ctatttttga taaaatccat atactttttt gtacattttt atcaacctgt ttataatata
     5701 aaccattttt tcaaaaaaag cactacccaa atttcatttt cttgtgtata attaaataca
     5761 atttcagaaa ggaaaaatta ttaacatgat tgttaaaaaa atgcccattt tacaagggtt
     5821 tccagacttt gagactgtta aatttttcac cggaaaattc ttccaaaaat acaattttac
     5881 acctgttttt tacgacattg aaaccaccgg attatcaaga aattccacgt atttatacct
     5941 gatcggagct gttggaattg aagatgaaac ttggtatttt tatcaatgga tggccgaaaa
     6001 tgccagtgaa gaagagacaa ttctgagaat tttttcacaa tttcttcagc aatataattt
     6061 gatgatttct tacaacggag aacgatttga ccagccctat ctggaagcac gatatgaaaa
     6121 atatggaatc ccctctccat ttacaggaaa acagtctctg gatctctacc tgatattaaa
     6181 accgttaaag tcacttttaa aactgcccgc catgcaacag ccctgcatgg aagaatttct
     6241 ggggatcaaa gacaggattt atgataatgg taaggaatgc attaaacttt acaaagattt
     6301 tctgaaaaaa agagatgcct ttacagctga tgaaattctg gggcacaacc tggaggatgt
     6361 gctgggactt ggaagaatct ttgatatgct gggatatctt tgcatctatg atggagatta
     6421 tgaagttaca tacagtgaat ttgacggaga caacctgatc ctgaaactga aactcccctg
     6481 cacactgcca caggaatttt ccaatggaaa caccgacttc tatctgacag gaaaagacga
     6541 agaaatcaat ttaattatca aaacaactga cgggaaactg aaacaatact atgcagatta
     6601 taaggattac tattatctcc cggaggagga tacggttatc ccgaaatctc tcggatccgg
     6661 aattgacaga aagcaccgga aagcagcaac cagaaatacc tgttacacct ggtttacctg
     6721 ctccgatgcc ttcctcagtt ctcccgtaca gcagaagcaa tatctgacat atacgctttc
     6781 ctgtctgatt ggaactctag aacgtgtctg aaaaatcctc tgtgatcata tataaatatc
     6841 gtcaaaagca atttccaatg gattgtgaag agaaaaagcc ctctcactgc tgactgagaa
     6901 aatataaccg tcaaattcca ttgtctcaaa aaagcatggc ctttctgagg attttccgag
     6961 gacaaaccca tctgctgtgg gaaccacttc aaaagaatcc aaaggaaggc tcattcctct
     7021 gcctgtcatt ttcatataac tttcttttaa tgtccagagc gtaaaaaacg ccttatcttt
     7081 gttcttcgca gccttgatgt aagcaagctc tgaatggtag aaataatgtt ctgccacctc
     7141 aagaggcgca ttggcatttt tctcaatatc gcacccgact tcgcagtctg acagcacacc
     7201 cacaacatag tcccccgcat gagatacatt aaaaaaaagg ccatccacaa ccggcttttc
     7261 attgtcagaa tatctcaggc agctttccgt aagcccgttt tcatcgagaa tttttctgat
     7321 gatgatccct gcacccagac ttcttttgcg gtcatcaggc atacgatacc tgatgacctt
     7381 ttctcttctt ctgatcccaa ccagatccag aagcctttca ttcttaagcg gatcctcaaa
     7441 atgattaata ttgatcctgt ataatttctg catctgatca acagttactt cttctgaata
     7501 tcgatcttgc tgtcaaaccc tgtaaggctg aatacatcgt aaacctcatc agaaacattg
     7561 atgatcttaa atccatcctt ttgagccatt tttttgtagg ctacgatcac ctgacgtaag
     7621 cctgcagatg aaatatactc cagatttgta aaatcaaata ccagacttgt gatgctgtct
     7681 tcaagtccgg acagagcctc ccctaactgg ggagctgtct gtgtatcaag ccatccgctg
     7741 atttccatag ttgctttgtt accttctgtt tttgtgataa tttccattgt aattttccct
     7801 cctgaatcaa tcaaaaaatg taagtctgtc aagtgctgca attgcatttt ccagatatct
     7861 gtcatctgta accggccatt tataatccag cctgtacaga acctgtgctg taaaacgatt
     7921 gctgtaatca atggtataga tttcattttc attatgtgag gtataggcga tcagtccgga
     7981 aaccgcatca gaatcctgac cggtctttgc aaattccttc actgctgcct caaactcctc
     8041 atctcttaca atatcaatcc tgaatccata gctgcgcatt gcgtagatca ggtctgccat
     8101 ataaatatga tggctgttgc atgcatggaa tacagtaaat ctccggtcgg tctgagccag
     8161 tctcagaact gccagcgcag tagaatcaat cggtgagaat tctgccacct catgcatacc
     8221 gcccataggg aatttaccta cagccgcata acctctcagg ctgcgaagga atccattggt
     8281 aatgaaatta atctggaact caccgtcaga gtttcggctc atcagattac ctacccggac
     8341 taccttgccg tccagtccct cggaaactgc ttccagaacc gccctctctg ccaggaattt
     8401 ggtacggata tattcattgg taatattctg tccgatgtac agatcattct cacagaaaac
     8461 tctggacatt ggcggaacac cgtcagaacc ctctcccgca acggaaaccg tagaaatctg
     8521 gatcagtcta cggccgttat tcttacagaa atcgatcaga ttttccacac cctgcacatt
     8581 aattctttcc agtacatcat cagccgcaaa atgctttacg caggcagcgc agttaatgat
     8641 ggtgctgaat ttgtattctg aaaatcctgt tacctgttcc tttgaggtaa tatccccatc
     8701 cacacagata atacggcttt caaacagctc tttgtatgga tcatcaaaat agtacatcag
     8761 catgttcatc attcgctttt cagacgattc atatttgccc ttacgtacaa gacagtaaac
     8821 cttaccgtca taattgtcaa tgaatgcttt aaggacatgg atccccagga aacctgtggc
     8881 acctgtgacc ataatatctc ccagcttttc ctttgtgatc cggtctgcat tttcttctgt
     8941 atttgcgctg atcacattct ggatcctgtt atagttataa tccgaaaatt cattcttgct
     9001 ctgtgcagcc tctgtaactc cgtcatcatc aaccaaagct gcaagttccc gtacagtagg
     9061 atatttgaaa atatccgcat ataccagtga aatattcttt gacagacaca taacagcaac
     9121 cttggatgca gtaagggaag atccgcccag ctcaaagaag ttgtcctcaa tccctactct
     9181 ttcaattccc agtgctttct caaaaatctc acagagtgct ctctgagctg cagtaaccgg
     9241 ctctacatcg ctggcagtgt tcgtggttac ctccggcatt ggcagtgctt ttttatcaat
     9301 cttaccgccc ggtgtcacag gcatttcctc aatgctgaca aagaaagacg gcatcatata
     9361 atccgggatc agcggctcca ggaaggtctt cagttcatcc tccgggatgg cttctcctgt
     9421 ataataagct gtgatatatt tatttccacc cttttcaatt actgtaacgg ctgcattttt
     9481 caccagctca tgtttcagaa gggcaccttc gatctcacca agctccacac gatatcctct
     9541 gatcttcacc tgtgaatcga tccggcctat gtactcaata tttccgtcac ctttcatgcg
     9601 gaccatatca ccggtcctgt aaagacggct ttcctgctca catacagcaa atggattttc
     9661 tacaaacaca gatgctgttt tttccggaag attatgatat cctctggcaa tctgccttcc
     9721 tgcgtgacaa agttcgccgg acgcacccac cggaagccgg ttcagattct catccacaat
     9781 gtagctgcgc acattccgct gtgattttcc gatcgggatg ttgtcatact gtctgtctac
     9841 caaaaactct gtggaagaaa ccgtattctc tgtaggaccg tagccattga tcatctgata
     9901 ggtacggtta cggtaatgct tgaatttctc gccgccaagt gtaacaaatt taagagcagg
     9961 tgcatcctcc agaagttctg taaccagttc tcccatctgg gtagggaagg ttacggtggt
    10021 gatctctttt tcctttatat atctgcttat ggcaatggcg tccttacgga tactctccgg
    10081 taaaatatac aggactgctc ctgcggtaag aggtgcaaac agatcgatca ctgacgcatc
    10141 gaaacagaag ctcgcaaact ctgccacaat gtcatccggt gaagtatttc tgctcagtgt
    10201 gatatattcg atcaggttca acagatttct gtgctcgatc ataacaccct ttggctttcc
    10261 tgtggagcct gaggtataga tcatataggc aaggttctcc ggtttcggag aaataagctc
    10321 tgcagaaagt tcaaaatcct cagcctcatc tggcacactg tccagactga tcacatttcc
    10381 gtcataaaat tccacaagat tctgatactg atcgatcaca aggagatttc ttgctcctga
    10441 atccttcagc atatattcaa ttctgctctg tggatactcc ggatccagag gaacataggc
    10501 tccgccggcc ttcataacac ccacataggc tactgtatat tcttttgtcc tgccgcacag
    10561 gatacctgct gcctgttccg ggccaaatcc gttttccgta agcttctgag caatataatc
    10621 agacattctg tccaactctc tgtaagtaaa atctccggag tcatcccgca ctgccggtct
    10681 gtccggatat ctggcagcca tctccttaaa cagatctatg aaggtctttc ctgcatgttc
    10741 cggaatatcc tccatctgag ttttttcctc aaacatcagc cggatatcag ccggatcgca
    10801 ttcccttaag attccctctg cagtggtttc cagattgtca gccagatacc ggatagtttc
    10861 ctcatggtac atatctcctc tgtactcaat ctcaaagaca aatctgttct tttcaatgga
    10921 aatgctgaca gaaaccggtg cctttgccat gttcaggctg acaggctcct cctgtgcata
    10981 ttccccgcca atggtgtcaa aagcaaaatt gtcgccctgg taaataacca tggcatctgc
    11041 cttaatatca aactcatggc tgatctgtga gaaaggataa atatcgttgt tcatggaatc
    11101 gatcagctgt ttctgtacac cgcttaagca atctttggct gttcctgaga aatcgcagaa
    11161 aacagggagt gtttttacca gcatacccac tgtttccgaa agtctggaat cgtttcttcc
    11221 atggtaaata gtggtaaata cagcatcctt tttgaaatta tattttccaa gtgtgatacc
    11281 aaaagcggaa atgaagaata cattctccgt aattccatgc tttttacaga attccttcac
    11341 atcctgcaca gaaatggatc tggtctctct gtggtaaagt tctgctgttg gagccgcacc
    11401 gtttttgtcc ggatagaagc tgatgcttcc acctgcatgt tcaaatactg acttataata
    11461 attctctgca tttttataga tatcacctgc cagggcatct ctgttatcca gtgccagatc
    11521 ataggaagta taaccttccg gttccagctt ctcaccgctg taagctctgt taatatcatt
    11581 aattataata gccagagatg taccatcggc aacaatgtgg tgaaggtcca ggaacagata
    11641 attgccatca caggttctgt agatttcaaa ccggaaaagc tgttcattaa acaacatata
    11701 tggacgtacc agagtgtctc tgttcattcc gtttaaaatc ggtgttttat aactgagccc
    11761 atcgtttcgt ttctgaagta catttccgtt gtcatccata aacagacggg ttttcagata
    11821 aggatgtgcc tcaacagtac tgtcaatggc ttctgccagt ctgtccagat ccaccttgtt
    11881 atcaagcttt aacagatacg ggatattgta aatggtagaa cccatatttg cagtacactc
    11941 aatgaaaatc ccctcctgag tgttggtaag aggataactt tcctgtactt cccttttgct
    12001 ttcttttccc gcagttttta caaattcctc catcattcgg atagtaggat gattcttaat
    12061 atctgaagtt ttgatcacaa tgtcaaaggc tttggagatc aggatattca gcttaatggc
    12121 agtgatagat gtcagacctg cctcataaat atctgtggta atcccaaaat ccgtataccc
    12181 cagaacctct gcgatacagt caaataatat ctgctgaacc tcattctcag gcttaatgat
    12241 ctccgctgct tttttctcag gcagaggaag agccttttta tttaccttct ggttctggtt
    12301 cagaggaatt ttgtcaatct gcatggtaac tgcaggtacc atataggcag gctttgtctc
    12361 tttaataaaa tcattcaggg cattgatatc aacagtgctg tccgatacca cataggcagc
    12421 aatatatttt ccaccatttg gatcatcaaa ggcaactaca gtggcatccc tgatgccctc
    12481 atatctgcgg atcacttcct caacctcaga aagctcaatc ctgaaacctc tgatcttaac
    12541 ctgggaatcc tttctgccaa tgatctggat atttccatcc ggaagaaatc ttgccacatc
    12601 acctgaatga tacatcactt cgtatcccgg tgtatcatca taaagattct ttgtatagac
    12661 ctcggcagtt ttttccggct tgttaagata tcctctggaa acctgccagc cggtgatcat
    12721 cagctctccg catgcaccgg gaggaagcat atgccccagc ttgtccgtaa tataaagctt
    12781 cacattgtca agtgcttttc cgatcgggac atttggataa tatttgtcca cttcaaatac
    12841 agtcgtaaaa atagtcgcct ctgtaggtcc ataagcattg ataaacttat aatcttttgg
    12901 cggctcacat ggaaccagtt tctctcctcc tacagaaaga tatctcaggc tcttacaatc
    12961 catctccagc gcaaactgcc ttcccacctg agtagtcata aaggaatgcg tgataccatt
    13021 ttcctcaaaa tagcgctgca gtccaatgaa atccagacgg atttcctccg gaataatgtg
    13081 aagctgtgca ccgtttgtga tggcaccgta aatatccatc atgcaggcat caaaaccaaa
    13141 ggaagcatat gcagctatcc tgcactccga atctatgcca taatatctct tgaaccagtg
    13201 acagaaagca gtaatatttc catattccag catacagccc tttggcacac ctgtggaacc
    13261 ggaagtatac aaaaggataa ac
//
