LOCUS       c00332_gnlPro..        10855 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JBBMAOED_332.
ACCESSION   c00332_gnlPro..
VERSION     c00332_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 01:12:57
            Original ID  :: gnl|Prokka|JBBMAOED_332
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10855
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10855
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4359:6605]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4360..6605
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..10855
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10855
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(3..143)
                     /locus_tag="ctg332_1"
                     /transl_table=11
                     /translation="MASLIFEHLKKVYPNGFVSVDDVSLSIEDGEFVVFHGPSGCGKST
                     IL"
     CDS             249..341
                     /locus_tag="ctg332_2"
                     /transl_table=11
                     /translation="MHKIREITVGVCYVDSILEKAEEAVCKYCM"
     CDS             286..2040
                     /locus_tag="ctg332_3"
                     /transl_table=11
                     /translation="MLIQFWKRRKKQCVSIVCSISILFSSIFFLNGCEATFLEEKKSSK
                     EAENERFTSFTEKLFCKEMAASQISLHYTLKEPEAYGIDKADTAYGTIQTDSTQIKTAA
                     ENIQQALYTFSYEKLNVKNKITYDLLKQYLRSLREEADYLYYEEPLNTVNGVQTQIPIV
                     LSEYQFYDRTDVEAYLDVLSETRDYFQQIIAFEREKADKGLFLSDEMADQVLEQCNAFL
                     AMGNGNYLYSTFVSRIGELQELSEKEKSDYIQQNARQMEEQVYPAYEDLIQAVKELKGK
                     GTNEKGLCYFPEGRKYYEWYIQQSVGVTDTIQELEQLTRRQISEDITGMEEAVNEAKQA
                     ATILEDGKAERILEKLKKGIGTAFPEIPKTSLRIKYVPEEMQEHLSPAFYMIPAIDYTE
                     ENVIYVNQTQMRDDLALFTTLAHEGYPGHLYQTIFFESTNPDPIRSILNFGGYVEGWAT
                     YAEMCSYYLMPLSKTQAAILQKNSSVILALYALADMGIHYEGWSRMDTVEFYAKYGIKD
                     AETVDKIYNLILGSPGNYLKYYIGYIKFLELKKEWIKSGNQSQKEFHKAVLSVGPAPFE
                     IVGKYFSL"
     CDS             2163..2756
                     /locus_tag="ctg332_4"
                     /transl_table=11
                     /translation="MKLMIASDIHGSAFYCEQMIEAYKREGADKLLLLGDILYHGPRND
                     LPEGYAPKEVIAMLNPMKKELLCVRGNCDTEVDQMVLEFPILADYCYLNLSGDPEEKNS
                     DVTIFATHGHVYNPHKLPMLKDGDILLNGHTHIPACEEILDMNGGKYQYLNPGSVSIPK
                     EGSEHSYMIYENGVFTWKNLAGEEYQTWKTVSHS"
     CDS             2732..3751
                     /locus_tag="ctg332_5"
                     /transl_table=11
                     /translation="MEDRFALLIDADNVSAKYIKPILDELSKYGNVTYKRIYGDWTKSN
                     SASWKEELLQNSITPIQQFSYTQGKNSTDSAMIIDAMDMLYTSELEGFCLVSSDSDFTK
                     LASRLRESGKMVIGMGEDKTPLPFRKACDIFTVLEVLLEDNTIEKEESEGKFYHPHVFG
                     RGQKKISGASLSSSNGRGSKEKIEKVSKEKIEEIVVKIITENQNNDRETGLGEVGSRLV
                     KVYPDFDVRRYGYSLLSKFLETLPKLKLIQEGTKVSVTLYEDKSKKDMLEEYIIRQIQM
                     TGDQGISLGTLGNRIRIQFGDFKVRDYGYSQFKQYIQSFPKVELIEDGERTRAVYVED"
     CDS             3790..4323
                     /locus_tag="ctg332_6"
                     /transl_table=11
                     /translation="MIKKWNAVCSWMLTLFLLGHMLTMSIPVLTGGQDYSDCQILAGGI
                     VATVLIHVVFCIVSYYPRRGVLNFHRYRKENWRLITQRISGIVILILLYPHMRVLHLII
                     SGASFSGGAKFLVLVTEILFAGAAFLHLSVSFSRSMLTLGLLKNDRMEKLVDYVTWIIC
                     GLLMVLTVAARIRL"
     CDS             4360..5931
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 153.1; E-value:
                     4.2e-47)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg332_7"
                     /sec_met_domain="FAD_binding_2 (E-value: 8.2e-48, bitscore:
                     153.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4e-15, bitscore:
                     45.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVLIIGNGIAGMSAAIEAAELDDEVILVSPVQSERTQSVMAAEG
                     INAVVDTAEEDSVVWHANDTLESGCFLEKEEDVRNLCEKAPEHLKWLDEMGVLFDRNED
                     DTWKVKASGGQSRKRTVYSGNSIGKQIVTAMTQKCLEYEIKGKIEKKIGLYFYSALIRD
                     EKCYGALFYNPESKMLIPVYADAVICATGGMNKLYGKTTGSELNDGYVTGKLFLQGVQL
                     RNLEFIQYYPTTVQRGNKRVIISESVRSEGWRLYYKNRSHSVYFMEEKYGTEGNLMSRD
                     LVAREIAMCPGQVYLENAKESIPVTPAIHFFMGGIKVDGMHQTNIAGLYAVGEAASKYH
                     GANCLGGNSLMTAVHSGRTAAHAVHEGQGQPMCEELFVPYIEHEQEKIERMEQMSEYRG
                     KYSATATLRKLMKIMSYGMDLIRDGEVLQDSIYALDSSLNELRTFPIDPMVSVYENYRL
                     YPMAVLGKATLMSAVERRESRGAHFRKDFPGEKSEFMKCSVAEFKDEKIRIYFEQESGE
                     KGGAVR"
     CDS             5928..6605
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 92; E-value: 7.4e-29)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg332_8"
                     /sec_met_domain="Fer2_3 (E-value: 1.4e-29, bitscore: 92.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 1.7e-10, bitscore: 31.0,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00024, bitscore: 11.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVRIKRQDDRRSAPYWQVFHFRGEGRITVAAILEKLNERDQLED
                     IKGKQCRKIRWECGCMQKMCGGCAMVINGHPALACGVFINTDDTEILRLEPLTKFPVVE
                     DLIVDRSVIWERQKEALMYLGIRKHPDPKEHDHQYSAAKCLKCGLCLEVCPNYLGAKDD
                     FYGAEFANNAYLLHSSSLNRKRALEKQYEEHFAKQCSKSLACRDICPAHLQTLSSISYM
                     NRR"
     CDS             complement(6774..7640)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     71; E-value: 2.1e-22)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg332_9"
                     /sec_met_domain="LysR_substrate (E-value: 6e-33, bitscore:
                     103.6, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 4e-23, bitscore: 71.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLTQLEYFCVAARYHNITRASKELFVTQPSVSNAIKALEEEFGV
                     NLFYRNNNKLTLTPEGEKFYQNAEELLAHADAVRSELHELRKQITPVRIGIPPMLGTIY
                     LPDMYLSLKEEFPDVDFRLYEYGSIKACELVLEEKLDLAIVNAEQSAIDKCNLHIIDNE
                     DLLFCVSKDHPLAEQSTLLLNMLTDESLVLFNTDSVQVMTLTRQFKAAGVNPHIVLNTS
                     QITTLINMVKTNHIGCFLYKSMVDMYPELVGIPVFPAIEQRIGVIWRKGKYQNAVTEKV
                     IRYLKNY"
     CDS             7872..9137
                     /locus_tag="ctg332_10"
                     /transl_table=11
                     /translation="MSPSTITLLFLLFAVIMFVLEKIPLGVTSMIVCIGLVVTGVLDVK
                     TAFAGFIDSNVILFVAMFIVGGALFETGMANKIGGIVTKFAKTERMLIIAIMVIVGLMS
                     GILSNTGTAAVLIPVVIGIAAKSGYKRSRLLMPLVFAAAMGGNLSLIGAPGNLIAQSAL
                     GEIGLKFGFFEYAIVGMPILIVGIIFYATIGYKLLPSHDVKDDGAFDTTKNFDNVPKWK
                     QWLSLIILVFTLLAMIFEDKIGIKLCISGGIGALLLILTGVISEKDALKSIDLKTIFLF
                     GGTLSLASALQETGAGEVIANKVIGALGANPSPYILTLVVFLLCCIMTNFMSNTATTAL
                     MVPICLSIAQGMGADPRAVLMACVIGGSCAYATPIGMPANTMVVGAGGYKFMDYVKAGF
                     PLIIIATVVSMIILPIAFPFFP"
     CDS             9244..10143
                     /locus_tag="ctg332_11"
                     /transl_table=11
                     /translation="MDKKAQVEQLTTYMANFVSYIGKVLPDDIKAKIDELAEKEDSPLS
                     KVIYQTMQKNQVLAKELNRPSCQDTGVLQFWVKCGTNFPLIGELEALLKEAVVKATFEA
                     PLRHNSVETFDEYNTGKNVGKGTPTVFWDIVPDSDQCEIYTYMAGGGCTLPGKAMVLMP
                     GEGYEGVTKFVLDVMTSYGLNACPPLLVGVGVATSVETAALLSKKALMRPLGSHNENER
                     AASMEKLLEDGINAIGLGPQGMGGKYSVMGVHIENTARHPSTIGVAVNVGCWSHRRGHI
                     VFDKDLNYTITTHSGVTL"
     CDS             10143..10769
                     /locus_tag="ctg332_12"
                     /transl_table=11
                     /translation="MLEIKDGKKILTTPVSAEDLKDIHAGDIIYLNGSMTTCRDVAHRR
                     LVEEGRELPVDVKDAAIFHAGPIIRPLENDKFEMVSVGPTTSMRMEKFEYEFVKESGVR
                     VIIGKGGMKENTERACKEFGAIHCVFPAGNAVVAATEVEEIVDAQWRDLGMPETLWHCR
                     VKEFGPLIVSIDTEGRNLFEENKVVFNERKEKAIEEICKHVSFIK"
ORIGIN
        1 cgtaaaattg tagattttcc gcatccgctt ggtccgtgga atacaacaaa ttcaccgtcc
       61 tcgatcgaga ggctgacatc gtctacagat acgaatccgt tcggatatac ttttttcaaa
      121 tgttcaaata ttaagctggc catacacaac gcctcctgta tcttatatag ttgtatttta
      181 tcacaaataa agaggggatg cattactgtt tggaaacaaa tttcagcgat gtataaataa
      241 ggaagccaat gcataaaatt agagaaataa ctgtcggagt ctgctatgtt gattcaattt
      301 tggaaaaggc ggaagaagca gtgtgtaagt attgtatgta gtatcagtat tcttttcagt
      361 tctattttct ttttaaacgg ttgtgaagca acatttttag aagaaaaaaa gagcagtaaa
      421 gaagcggaga atgaaagatt tacatcgttt acagaaaaat tgttttgcaa agagatggct
      481 gcaagccaga tcagtctgca ctatacatta aaagagccag aagcgtatgg gattgataaa
      541 gcggatacag catatggaac gatacagaca gacagtactc agattaagac agcagcggag
      601 aatatacagc aggcattgta tacattttct tatgaaaaac tgaatgtaaa gaataaaatt
      661 acatacgatc tgttaaagca atatctgaga agtttgagag aagaagcgga ttatctgtat
      721 tatgaagaac cgttaaatac agtcaatgga gtacagacgc agattccaat tgtattatct
      781 gaatatcagt tttatgacag gacagatgtg gaggcgtatc tggatgtttt aagtgagaca
      841 agggattatt ttcaacagat cattgcattt gaaagagaaa aagcagacaa aggattgttt
      901 ttgtcagatg aaatggcgga tcaggtgtta gaacaatgta atgcatttct tgcaatggga
      961 aatggaaatt atctgtactc gacatttgtg tccagaattg gtgaattaca ggaactgtct
     1021 gaaaaagaaa agagtgatta tattcagcag aacgccaggc agatggaaga gcaggtttat
     1081 ccggcgtatg aggatttgat acaggcggtt aaggaattga aagggaaggg aacgaatgaa
     1141 aagggattgt gttattttcc ggaagggaga aaatactacg aatggtatat acagcagagt
     1201 gtaggagtga cagacacgat tcaagagctt gagcaactaa cgcgcagaca aatttcagaa
     1261 gatattaccg gtatggaaga agcagtcaac gaagcgaagc aggcagcaac aatattggaa
     1321 gatgggaaag cagaaagaat tttagaaaag ttaaaaaaag ggatagggac tgcatttcct
     1381 gagattccaa aaacttctct gcggataaaa tatgtaccgg aggaaatgca ggaacattta
     1441 agtcccgcat tttatatgat accggcaatt gactatacag aagaaaatgt aatttatgta
     1501 aaccaaacac agatgcgaga tgatttggca ctgtttacaa cgttggcaca tgaggggtat
     1561 ccgggacatc tgtaccagac aatatttttt gaaagcacga atcctgatcc catcaggagt
     1621 attttaaatt ttggcggata tgtagaaggc tgggcaactt atgcggaaat gtgcagctat
     1681 tatctgatgc cgttatctaa gactcaggca gcaattcttc agaagaatag ttcagtgatt
     1741 cttgcacttt atgcattggc agatatggga atccattacg aaggatggag cagaatggat
     1801 acagtagaat tttatgcaaa atatgggatt aaagatgctg aaacggttga taaaatctat
     1861 aatctgattc tgggatcgcc gggaaattat ttgaaatatt atatcggata tataaaattt
     1921 ctggagttga aaaaggaatg gataaaatct ggaaatcaat cccagaaaga attccataaa
     1981 gctgtgctga gtgtgggtcc ggcgcctttt gaaattgtag gaaaatattt ttctctgtga
     2041 ttcattctgt gttataatat ccacaggcac aaaataataa gaggcggtgt ctcaagaaaa
     2101 gagtcactgc ttttttcatt tattatagag aaactattta gaaagacagg aggacgtgaa
     2161 aaatgaaatt aatgattgca tctgacatcc atggctcagc attttattgt gaacagatga
     2221 ttgaggctta taaaagagaa ggcgcagaca aattattatt gttaggagat attctttatc
     2281 atggaccgag aaatgatctg ccggaaggat atgcaccgaa ggaagtgatc gcaatgctta
     2341 atccaatgaa gaaagaactt ctctgtgtga gaggaaattg tgatacagaa gtggatcaga
     2401 tggtattgga gttcccaatt ctggcagatt attgttatct gaatctgtca ggagatccgg
     2461 aagaaaagaa cagtgatgtt acaatatttg caacacacgg acatgtgtat aatccacata
     2521 agcttccgat gctgaaagac ggagatattt tgttgaacgg acatacgcat attccggcat
     2581 gtgaggaaat ccttgatatg aacggtggaa aatatcagta cttaaatcca ggttctgtct
     2641 cgattccgaa ggaaggatcc gagcacagtt atatgattta tgaaaacggt gtatttacat
     2701 ggaagaatct tgcaggagag gagtatcaga catggaagac cgtttcgcac tcttaatcga
     2761 tgcggataat gtatctgcaa aatatattaa gccaatcctg gatgaattat ctaaatatgg
     2821 aaacgtgact tacaaacgaa tttacggaga ctggacaaag tcaaacagtg cgagctggaa
     2881 ggaagaactt cttcaaaatt ctattacgcc gattcagcag ttcagttata cacagggaaa
     2941 gaattctaca gattctgcca tgatcattga tgcaatggac atgctctata caagtgaatt
     3001 ggaggggttc tgtctggtat cgagtgacag tgattttaca aagcttgcaa gccggcttcg
     3061 tgaaagtgga aagatggtaa tcggaatggg cgaggacaag acaccgcttc cgttccgtaa
     3121 agcctgtgat atcttcaccg tattagaggt gcttctggaa gacaacacga tagagaagga
     3181 agagagtgaa ggaaagtttt atcatccgca tgtgtttgga aggggacaga agaaaatttc
     3241 cggtgcttca ttatcatcgt cgaatggaag aggttcaaaa gaaaagattg aaaaggtatc
     3301 aaaggaaaaa atagaagaaa tcgtggttaa gatcattacg gaaaaccaga ataacgacag
     3361 ggaaaccggg cttggtgaag ttggaagccg gctggttaaa gtatatccgg actttgatgt
     3421 tcgacgttat ggttacagtt tgttatccaa gttccttgaa actttaccga aattaaagct
     3481 gatccaggaa ggaacgaaag tttcggttac tctgtatgaa gataagagta agaaagatat
     3541 gcttgaagag tatattatcc gacagatcca gatgacaggg gatcagggga tctctcttgg
     3601 aacactgggg aatcgaattc gtattcagtt tggtgatttt aaagtacggg attatggata
     3661 ctcacaattt aagcagtata tacaaagttt tccaaaggta gaattgatcg aagatggaga
     3721 gcgtacccgc gctgtttatg tggaagatta aaagtagaga gaataagata cagaaggggg
     3781 tgctgattaa tgataaagaa atggaacgca gtatgttcct ggatgcttac gttattctta
     3841 cttggacata tgcttaccat gtccattcct gtgttgacag gtggacagga ttattctgat
     3901 tgtcagatac ttgcaggagg gattgtggcg acagttttga ttcatgtagt tttttgtatt
     3961 gtaagttatt atccaagacg tggagtactt aattttcaca gatacaggaa agagaattgg
     4021 agattaatta cgcagagaat cagtggaatt gttatactga ttttattgta tccacacatg
     4081 agagtacttc atcttataat aagtggagca tcattttctg gtggagcaaa gtttcttgta
     4141 ttagtgacgg agattctctt tgcaggtgcg gcatttctgc atctgagtgt atcgttcagc
     4201 cgttctatgc tgacgcttgg tttgttgaag aacgatagga tggagaagct tgtggattat
     4261 gtaacatgga tcatctgtgg attattaatg gttcttacgg tggctgcgcg gataagattg
     4321 taggaatagg tgagattttt aggaaagaga agatgacaaa tgaaggtatt gattatagga
     4381 aatggaattg ccgggatgtc tgctgcaata gaagcagcag aacttgatga tgaggtaatt
     4441 cttgtatcac cggttcagtc agaacgtaca cagtcagtta tggcagcaga aggaatcaat
     4501 gcagtagttg ataccgcaga ggaggattct gtagtgtggc atgcgaatga tacgctggag
     4561 agtgggtgtt ttcttgaaaa agaagaggat gtgagaaatc tctgtgagaa agcaccggaa
     4621 catctgaaat ggctggatga gatgggagtt ctttttgatc gaaatgaaga tgatacatgg
     4681 aaagtgaaag cttccggagg acagagtaga aaaaggactg tttattcagg taattccatt
     4741 ggaaaacaga ttgttacggc aatgacacag aaatgcctgg agtatgagat taaaggtaaa
     4801 atagaaaaga aaatcggatt gtatttttat tccgctctta ttcgggatga aaagtgttat
     4861 ggagcgttat tttataatcc agaatctaaa atgttgattc cggtttatgc ggatgcagta
     4921 atctgtgcta ccggtggaat gaacaagcta tatggaaaaa ccactggatc tgaattaaat
     4981 gatggttatg tgacaggaaa gcttttttta cagggagtgc agctgagaaa tctcgaattt
     5041 atccagtatt atccgaccac ggttcagaga ggaaataaga gggttataat ctcggaatct
     5101 gtcagaagtg aaggttggag actttattat aagaatagaa gtcacagtgt ttatttcatg
     5161 gaagaaaagt atggtacgga aggcaatctg atgtcaagag atcttgtcgc aagagaaatt
     5221 gcaatgtgtc ccggacaggt ttatctggag aatgcaaaag aatcgatccc tgtaacgccg
     5281 gcaatccatt tctttatggg tggtattaaa gtggacggaa tgcatcagac gaatattgca
     5341 ggattgtatg ctgtgggaga agctgcgtca aaatatcatg gtgcaaattg ccttggtgga
     5401 aattcattga tgacagcagt tcattcggga agaacagcag cgcatgcggt gcatgaggga
     5461 cagggtcagc cgatgtgtga agaattgttt gttccttata ttgagcatga gcaggagaaa
     5521 attgagcgta tggaacagat gtcagagtat cggggcaagt attcagcgac agcaacactg
     5581 cgtaaattaa tgaagatcat gagttatggc atggatttga tccgtgatgg agaagttctt
     5641 caggatagta tttacgcatt ggattccagc ttgaatgagc tgaggacatt tccgattgat
     5701 ccaatggtat ctgtttatga aaattacaga ttatatccga tggctgttct tggaaaagcg
     5761 acacttatga gtgctgtgga aagacgtgaa tcaagaggag ctcatttccg aaaagatttt
     5821 ccaggtgaaa aatcagaatt catgaaatgt tccgttgcag agtttaaaga cgaaaaaatc
     5881 aggatttatt ttgaacagga gtcaggagaa aagggaggcg ctgtgagatg aaagtaagaa
     5941 tcaaaagaca ggatgaccga agatcagcgc cgtattggca agtttttcat ttcagaggag
     6001 agggaagaat tacagtagcc gcgattctcg agaagttaaa tgaacgtgac cagctggaag
     6061 atatcaaagg aaaacaatgt agaaaaatcc gttgggaatg tggttgtatg cagaaaatgt
     6121 gcggaggttg tgcaatggtg atcaacgggc atccggcatt ggcatgtgga gtgttcatta
     6181 atacagatga tacagagatt ttaaggctgg aaccacttac aaaatttccg gttgtggaag
     6241 atctgattgt tgacagatct gtaatatggg aacgccagaa ggaagcactg atgtaccttg
     6301 gaattcggaa acatccagat ccgaaagagc atgatcatca gtattcggca gcaaagtgtc
     6361 tgaaatgtgg actttgtctg gaagtatgtc cgaattatct tggggcaaaa gatgatttct
     6421 atggcgcaga gtttgcaaat aatgcgtatc ttctgcattc ttccagtctg aatcgaaagc
     6481 gggcattgga gaaacagtat gaagaacatt ttgcgaagca atgttcgaaa tcactggcat
     6541 gcagagatat ctgtccggcg cacctgcaga cgttgtcgtc gatttcttat atgaatagaa
     6601 gatagaaatg agtcaggtat tattcgctga atgcggtttc tcagtgggaa atgcaaggag
     6661 aacttaaaga aaatggcaga aaaagagaat taaaatctat aaggggcggg tacagtacaa
     6721 tgtatccgcc tttaaaaata atgagttgtt aaataaattg attggcataa cgattaataa
     6781 ttcttcaaat atctaataac cttttcggtc acagcgttct gatactttcc ttttctccag
     6841 ataacaccaa tgcgctgttc aattgcagga aagacaggta ttccgacaag ttcaggatac
     6901 atatccacca tagacttata caaaaaacag ccaatatgat tagtctttac catattgatc
     6961 agcgttgtga tctgactggt gttcagaaca atgtgtgggt ttactcctgc ggccttgaac
     7021 tgacgggtca gtgtcataac ctgaacagaa tcagtgttaa acagaaccaa tgactcatca
     7081 gtcagcatgt ttaaaagaag cgtggattgt tctgcaagtg gatgatcctt tgatacgcag
     7141 aagagcagat cttcattatc aataatatga aggttgcatt tatcaatcgc agactgttct
     7201 gcattgacaa tcgcgaggtc aagtttctcc tccagaacaa gttcacaggc tttgattgat
     7261 ccatattcat ataggcggaa atctacgtca gggaattctt ccttcaaaga aagatacata
     7321 tccggcaggt aaatggttcc aagcattggc gggattccga tgcggacagg tgtaatctgc
     7381 ttacggagtt cgtgcagttc agatctgaca gcatccgcat gagccaaaag ttcttcggca
     7441 ttttgataga acttttcacc ttccggtgtc agagtcagtt tattattgtt tctatagaaa
     7501 agattcacgc cgaattcttc ttccaaagct ttgatcgcgt tagataccga aggctgggta
     7561 acaaaaagct ctttggatgc gcgggtgatg ttgtggtatc ttgcagcaac acagaaatat
     7621 tcgagttgtg tcagtttcat ttgtaaaaac ctcctatatc taaattattg cgtactaaag
     7681 gtttccatag ttttttctta tagtaccata tttttttcag aatgtacatt ttcgattgta
     7741 ttttctataa tacaaccata gcagagaggt aatcgaaacg gccggaaatt acttaaagcg
     7801 aagctaaaaa taatagctga aaaagttaag aagtaaaaga aaaacagaaa caaaggaatg
     7861 gaggaaaaca tatgagtcca tcaacaataa ctcttctgtt tctcctgttt gcggtaatca
     7921 tgtttgtatt agaaaagata ccgcttggag taacatcaat gattgtctgt atcggtcttg
     7981 tagtgactgg ggttttagac gtgaaaacag cctttgcagg gttcattgac agtaacgtaa
     8041 tcctttttgt agcaatgttt atcgtaggag gtgcgttatt tgaaacagga atggcgaata
     8101 aaatcggagg aattgttacg aagttcgcca agacagaaag aatgctgatc attgcgatta
     8161 tggtgatcgt aggattgatg agcggaatcc tgtcaaacac aggaactgca gcagttctga
     8221 ttccggtagt tatcggaatt gcagcaaaat caggatacaa aagatcccga cttctgatgc
     8281 cgcttgtatt tgcagcagca atgggaggaa atctttccct gatcggtgca ccgggaaatc
     8341 taatcgcaca gagtgcactc ggtgaaatcg gactaaaatt cggattcttc gagtatgcaa
     8401 ttgttggtat gccgatcctg atcgtaggaa ttattttcta cgcaacaatt ggttacaaac
     8461 tgcttccaag tcacgatgtg aaggatgacg gagcttttga tacaacaaag aatttcgata
     8521 atgtgccgaa atggaaacag tggttatcac tgattatcct ggtatttaca ttgctggcaa
     8581 tgattttcga agataaaatc ggtatcaagc tttgtatttc cggtggaatc ggagcactgc
     8641 ttctgattct tacaggagtt atctcagaaa aagatgcact taagtcaatc gatcttaaga
     8701 caatcttcct gtttggtggt acactttccc tcgcatctgc tcttcaggag acaggagccg
     8761 gagaagtgat cgctaataaa gtaatcggag cgttgggtgc gaacccatct ccatatatcc
     8821 tgacacttgt tgtattcctg ctgtgttgta tcatgacaaa cttcatgtca aatacagcaa
     8881 caacagcact gatggttcca atctgtctct caattgcaca ggggatggga gcggatccaa
     8941 gagctgtact gatggcatgt gtaatcggtg gttcctgcgc atatgcaaca ccaatcggaa
     9001 tgcctgcgaa cacaatggta gtcggagccg gtggatataa gtttatggac tatgtaaaag
     9061 caggattccc attgatcatc attgcaacag ttgtaagtat gattatcctt ccaatcgcat
     9121 ttccattctt cccgtaagaa gacatgttgt tggagtgaga tataaaagaa actataaaac
     9181 aatgaactaa cctaatcatc aaagttactg gaaattgcag cagtaatgaa aggagaccta
     9241 aaaatggata aaaaagcaca ggtagagcag cttactactt atatggcgaa ctttgtttcc
     9301 tatattggta aagtactgcc ggatgacatc aaagcaaaga ttgacgagct tgcagaaaaa
     9361 gaagacagcc cgctttcaaa ggttatttat cagacaatgc agaagaacca ggttcttgca
     9421 aaagagctga acagaccaag ctgtcaggac acaggagtat tacagttctg ggtaaaatgc
     9481 ggaacaaact tcccactcat tggagaactg gaagcactct taaaggaagc agttgtaaag
     9541 gctacatttg aagcaccgct tcgtcataac agtgttgaga catttgatga gtataacaca
     9601 ggaaagaatg taggaaaagg aacaccgaca gtattctggg atatcgtacc ggacagtgat
     9661 cagtgcgaaa tctatacata catggcaggt ggtggatgta cactgccagg aaaagctatg
     9721 gttcttatgc cgggcgaagg atacgaagga gttacaaaat ttgttcttga tgttatgaca
     9781 tcttacggat tgaatgcatg tcctccgctg cttgttggtg tcggtgttgc tacatctgtt
     9841 gagacagcag cattactttc caagaaagct cttatgagac cgcttggaag ccacaatgaa
     9901 aatgaacgtg cagcgtctat ggagaagctg cttgaggatg gaattaacgc aattggactt
     9961 ggaccacagg gaatgggcgg aaagtattct gttatgggag ttcacattga gaatacagca
    10021 agacatccat ccacaattgg agttgctgtt aatgttggat gctggtcaca cagacgtgga
    10081 cacattgtat ttgataagga ccttaactac acaatcacaa cacattcggg ggtgacatta
    10141 taatgctgga aataaaagat ggaaaaaaga ttttaacaac accagtctca gctgaggatc
    10201 tcaaagatat tcatgcagga gatatcattt atctgaacgg aagcatgaca acttgccgtg
    10261 acgttgcaca cagaagactc gttgaagaag gacgtgagct tccggttgat gtaaaagatg
    10321 cagcaatctt ccacgcaggc ccgatcatca gaccacttga aaatgataaa tttgaaatgg
    10381 tttctgtagg accgacaaca agtatgcgta tggaaaaatt tgagtatgaa tttgtaaaag
    10441 agtccggagt tcgtgtgatc atcggaaaag gtggaatgaa agaaaacaca gagcgtgcat
    10501 gtaaagaatt cggagcaatt cattgcgtat tcccagcagg aaatgctgtt gttgcagcaa
    10561 cagaagttga ggaaatcgtt gatgctcagt ggagagacct cggaatgcct gagacactgt
    10621 ggcactgccg cgtaaaagag ttcggaccac tgatcgtatc tattgacaca gagggacgca
    10681 acctgtttga agagaacaaa gtagtcttca atgagagaaa agaaaaagcg atcgaagaga
    10741 tctgcaaaca tgtaagtttt attaaataag ttgtgtcagg acattaaagt ttactcgaaa
    10801 aatctgagcc actcatgcct gaaaagcgac tcagatttat gaaatcagaa attaa
//
