LOCUS       gnlProkkaGJDMADOB_111   7126 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GJDMADOB_111.
ACCESSION   gnlProkkaGJDMADOB_111
VERSION     gnlProkkaGJDMADOB_111
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 22:33:33
            Original ID  :: gnl|Prokka|GJDMADOB_111
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7126
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..933
                     /locus_tag="ctg111_1"
                     /transl_table=11
                     /translation="MPVFYDIETTGLSRNSTYLYLIGAVGIEDETWNFYQWMAENANEE
                     ETILRIFSQFLQQCDLLISYNGDRFDQPYLEARYEKYGIPSPFTGKQSLDLYLTLKPLK
                     SLLKLPAMKQPCMEEFLGIKDRIYDNGKECIKLYKDFLKKRDAFTADEILGHNLEDVLG
                     LGRIFDMLGYLCIYDGDYEVTYSEFDGDNLILKLKLPCTLPQEFSNGNTDFYLTGKDEE
                     INLIIKTTDGKLKQYYADYKDYYYLPEEDTVIPKSLGSGIDRKHRKAATRNTCYTWFTC
                     SDAFLSSPVQQKQYLTYTLSCLIGTLERV"
     protocluster    1..7126
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1928:7124]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1929..7124
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..7126
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7126
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             complement(948..1595)
                     /NRPS_PKS="Domain: ACPS (98-159). E-value: 2.8e-13. Score:
                     41.7. Matches aSDomain: nrpspksdomains_ctg111_2_ACPS.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012:4'-phosphopantetheinyl transferase (Score: 129;
                     E-value: 2.6e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg111_2"
                     /transl_table=11
                     /translation="MQKLYRININHFEDPLKNERLLDLVGIRRREKVIRYRMPDDRKRS
                     LGAGIIIRKILDENGLTESCLRYSDNEKPVVDGLFFNVSHAGDYVVGVLSDCEVGCDIE
                     KNANAPLEVAEHYFYHSELAYIKAAKNKDKAFFTLWTLKESYMKMTGRGMSLPLDSFEV
                     VPTADGFVLGKSSERPCFFETMEFDGYIFSVSSERAFSLHNPLEIAFDDIYI"
     aSDomain        complement(1119..1301)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg111_2_ACPS.1"
                     /evalue="2.80E-13"
                     /label="ctg111_2_ACPS.1"
                     /locus_tag="ctg111_2"
                     /protein_end="159"
                     /protein_start="98"
                     /score="41.7"
                     /tool="antismash"
                     /translation="VGCDIEKNANAPLEVAEHYFYHSELAYIKAAKNKDKAFFTLWTLK
                     ESYMKMTGRGMSLPLD"
     CDS             complement(1607..1909)
                     /locus_tag="ctg111_3"
                     /transl_table=11
                     /translation="MEIITKTEGNKATMEISGWLDTQTAPQLGEALSGLEDSITSLVFD
                     FTNLEYISSAGLRQVIVAYKKMAQKDGFKIINVSDEVYDVFSLTGFDSKIDIQKK"
     CDS             complement(1929..7124)
                     /NRPS_PKS="Domain: PP-binding (267-328). E-value: 9.4e-11.
                     Score: 34.0. Matches aSDomain:
                     nrpspksdomains_ctg111_4_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_LCL (340-616). E-value:
                     1.2e-38. Score: 124.6. Matches aSDomain:
                     nrpspksdomains_ctg111_4_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (764-1155). E-value:
                     1.3e-94. Score: 309.0. Matches aSDomain:
                     nrpspksdomains_ctg111_4_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1260-1327). E-value: 3.7e-21.
                     Score: 67.0. Matches aSDomain:
                     nrpspksdomains_ctg111_4_PCP.1"
                     /NRPS_PKS="Domain: NAD_binding_4 (1371-1609). E-value:
                     5.8e-36. Score: 115.7. Matches aSDomain:
                     nrpspksdomains_ctg111_4_NAD_binding_4.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     144.5; E-value: 9.1e-44)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg111_4"
                     /sec_met_domain="Condensation (E-value: 1.4e-49, bitscore:
                     156.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.5e-104, bitscore:
                     336.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.2e-12, bitscore:
                     34.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4e-09, bitscore:
                     24.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.3e-15, bitscore:
                     43.3, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 4.1e-37, bitscore:
                     115.7, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMTTQVGRQFALEMDCKSLRYLSVGGEKMVPCEAPKDYKFINAYG
                     PTEATIFTTVFEVGKYYPNVPIGKALDNVKLYITDKLGHMLPPGACGELMITGWQVSRG
                     YLNKPEKTAEVYTKNLYDDTPGYEVMYHSGDVARFLPDGNIQIIGRKDSQVKIRGFRIE
                     LSEVEEVIRRYEGIRDATVVAFDDPNGGKYIAAYVVSDSTVDINALNDFIKETKPAYMV
                     PAVTMQIDKIPLNQNQKVNKKALPLPEKKAAEIIKPENEVQQILFDCIAEVLGYTDFGI
                     TTDIYEAGLTSITAIKLNILISKAFDIVIKTSDIKNHPTIRMMEEFVKTAGKESKREVQ
                     ESYPLTNTQEGIFIECTANMGSTIYNIPYLLKLDNKVDLDRLAEAIDSTVEAHPYLKTR
                     LFMDDNGNVLQKRNDGLSYKTPILNGMNRDTLVRPYMLFNEQLFRFEIYRTCDGNYLFL
                     DLHHIVADGTSLAIIINDINRAYSGEKLEPEGYTSYDLALDNRDALAGDIYKNAENYYK
                     SVFEHAGGSISFYPDKNGAAPTAELYHRETRSISVQNVKEFCKKHGITENVFFISAFGI
                     TLGKYNFKKDAVFTTIYHGRNDSRLSETVGMLVKTLPVFCDFSGTAKDCLSGVQKQLID
                     SMNNDIYPFSQISHEFDIKADAMVIYQGDNFAFDTIGGEYAQEEPVSLNMAKAPVSVSI
                     SIEKNRFVFEIEYRGDMYHEETIRYLADNLETTAEGILRECDPADIRLMFEEKTQMEDI
                     PEHAGKTFIDLFKEMAARYPDRPAVRDDSGDFTYRELDRMSDYIAQKLTENGFGPEQAA
                     GILCGRTKEYTVAYVGVMKAGGAYVPLDPEYPQSRIEYMLKDSGARNLLVIDQYQNLVE
                     FYDGNVISLDSVPDEAEDFELSAELISPKPENLAYMIYTSGSTGKPKGVMIEHRNLLNL
                     IEYITLSRNTSPDDIVAEFASFCFDASVIDLFAPLTAGAVLYILPESIRKDAIAISRYI
                     KEKEITTVTFPTQMGELVTELLEDAPALKFVTLGGEKFKHYRNRTYQMINGYGPTENTV
                     SSTEFLVDRQYDNIPIGKSQRNVRSYIVDENLNRLPVGASGELCHAGRQIARGYHNLPE
                     KTASVFVENPFAVCEQESRLYRTGDMVRMKGDGNIEYIGRIDSQVKIRGYRVELGEIEG
                     ALLKHELVKNAAVTVIEKGGNKYITAYYTGEAIPEDELKTFLEPLIPDYMMPSFFVSIE
                     EMPVTPGGKIDKKALPMPEVTTNTASYVEPVTAAQRALCEIFEKALGIERVGIEDNFFE
                     LGGSSLTASKVAVMCLSKNISLVYADIFKYPTVRELAALVDDDGVTEAAQSKNEFSDYN
                     YNRIQNVISANTEENADRITKEKLGDIMVTGATGFLGIHVLKAFLDNYDGKVYCLVRKG
                     KYESPEKRMMNMLMYYFDDPYKELFESRIICVDGDITSKEQVTGFSEYKFSTIINCAAC
                     VKHFAADDVLERINVQGVENLIDFCKNNGRRLIQISTVSVAGEGSDGVPPMSRVFCEND
                     LYIGQNITNEYIRTKFLAERAVLEAVSEGLDGKVVRVGNLMSRNSDGEFQINFITNGFL
                     RSLRGYVAVGKFPMGGMHEVAEFSPIDSTALAVLRLAQTDRRFTVFHACNSHHIYMADL
                     IYAMRSYGFRIDIVRDEEFEAAVKEFAKTGQDSDAVSGLIAYTSHNENEIYTIDYSNRF
                     TAQVLYRLDYKWPVTDDRYLENAIAALDRLTFFD"
     aSDomain        complement(2298..3011)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg111_4_NAD_binding_4.1"
                     /evalue="5.80E-36"
                     /label="ctg111_4_NAD_binding_4.1"
                     /locus_tag="ctg111_4"
                     /protein_end="1609"
                     /protein_start="1371"
                     /score="115.7"
                     /tool="antismash"
                     /translation="VTGATGFLGIHVLKAFLDNYDGKVYCLVRKGKYESPEKRMMNMLM
                     YYFDDPYKELFESRIICVDGDITSKEQVTGFSEYKFSTIINCAACVKHFAADDVLERIN
                     VQGVENLIDFCKNNGRRLIQISTVSVAGEGSDGVPPMSRVFCENDLYIGQNITNEYIRT
                     KFLAERAVLEAVSEGLDGKVVRVGNLMSRNSDGEFQINFITNGFLRSLRGYVAVGKFPM
                     GGMHEVAEFSPIDSTA"
     aSModule        complement(2298..6104)
                     /complete
                     /domains="nrpspksdomains_ctg111_4_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg111_4_AMP-binding.1"
                     /domains="nrpspksdomains_ctg111_4_PCP.1"
                     /domains="nrpspksdomains_ctg111_4_NAD_binding_4.1"
                     /locus_tags="ctg111_4"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(3144..3344)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg111_4_PCP.1"
                     /evalue="3.70E-21"
                     /label="ctg111_4_PCP.1"
                     /locus_tag="ctg111_4"
                     /protein_end="1327"
                     /protein_start="1260"
                     /score="67.0"
                     /tool="antismash"
                     /translation="RALCEIFEKALGIERVGIEDNFFELGGSSLTASKVAVMCLSKNIS
                     LVYADIFKYPTVRELAALVDDD"
     CDS_motif       complement(3630..3695)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_4_0010"
                     /evalue="5.60E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg111_4"
                     /protein_end="1165"
                     /protein_start="1143"
                     /score="37.5"
                     /tool="antismash"
                     /translation="YIGRIDSQVKIRGYRVELGEIE"
     aSDomain        complement(3660..4832)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg111_4_AMP-binding.1"
                     /evalue="1.30E-94"
                     /label="ctg111_4_AMP-binding.1"
                     /locus_tag="ctg111_4"
                     /protein_end="1155"
                     /protein_start="764"
                     /score="309.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FKEMAARYPDRPAVRDDSGDFTYRELDRMSDYIAQKLTENGFGPE
                     QAAGILCGRTKEYTVAYVGVMKAGGAYVPLDPEYPQSRIEYMLKDSGARNLLVIDQYQN
                     LVEFYDGNVISLDSVPDEAEDFELSAELISPKPENLAYMIYTSGSTGKPKGVMIEHRNL
                     LNLIEYITLSRNTSPDDIVAEFASFCFDASVIDLFAPLTAGAVLYILPESIRKDAIAIS
                     RYIKEKEITTVTFPTQMGELVTELLEDAPALKFVTLGGEKFKHYRNRTYQMINGYGPTE
                     NTVSSTEFLVDRQYDNIPIGKSQRNVRSYIVDENLNRLPVGASGELCHAGRQIARGYHN
                     LPEKTASVFVENPFAVCEQESRLYRTGDMVRMKGDGNIEYIGRIDSQVKIR"
     CDS_motif       complement(3786..3875)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_4_0009"
                     /evalue="1.10E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg111_4"
                     /protein_end="1113"
                     /protein_start="1083"
                     /score="40.2"
                     /tool="antismash"
                     /translation="PVGASGELCHAGRQIARGYHNLPEKTASVF"
     CDS_motif       complement(3975..4004)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_4_0008"
                     /evalue="5.00E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg111_4"
                     /protein_end="1050"
                     /protein_start="1040"
                     /score="6.8"
                     /tool="antismash"
                     /translation="YGPTENTVSS"
     CDS_motif       complement(4353..4412)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_4_0007"
                     /evalue="4.30E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg111_4"
                     /protein_end="924"
                     /protein_start="904"
                     /score="34.5"
                     /tool="antismash"
                     /translation="AYMIYTSGSTGKPKGVMIEH"
     CDS_motif       complement(4605..4643)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_4_0006"
                     /evalue="1.80E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg111_4"
                     /protein_end="840"
                     /protein_start="827"
                     /score="17.9"
                     /tool="antismash"
                     /translation="GVMKAGGAYVPLD"
     aSDomain        complement(5277..6104)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg111_4_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.20E-38"
                     /label="ctg111_4_Condensation_LCL.1"
                     /locus_tag="ctg111_4"
                     /protein_end="616"
                     /protein_start="340"
                     /score="124.6"
                     /tool="antismash"
                     /translation="ESYPLTNTQEGIFIECTANMGSTIYNIPYLLKLDNKVDLDRLAEA
                     IDSTVEAHPYLKTRLFMDDNGNVLQKRNDGLSYKTPILNGMNRDTLVRPYMLFNEQLFR
                     FEIYRTCDGNYLFLDLHHIVADGTSLAIIINDINRAYSGEKLEPEGYTSYDLALDNRDA
                     LAGDIYKNAENYYKSVFEHAGGSISFYPDKNGAAPTAELYHRETRSISVQNVKEFCKKH
                     GITENVFFISAFGITLGKYNFKKDAVFTTIYHGRNDSRLSETVGMLVKTLPVFC"
     CDS_motif       complement(5682..5747)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_4_0005"
                     /evalue="8.70E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg111_4"
                     /protein_end="481"
                     /protein_start="459"
                     /score="24.7"
                     /tool="antismash"
                     /translation="LHHIVADGTSLAIIINDINRAY"
     CDS_motif       complement(5928..6038)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_4_0004"
                     /evalue="1.40E-07"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg111_4"
                     /protein_end="399"
                     /protein_start="362"
                     /score="24.0"
                     /tool="antismash"
                     /translation="TIYNIPYLLKLDNKVDLDRLAEAIDSTVEAHPYLKTR"
     aSDomain        complement(6141..6323)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg111_4_PP-binding.1"
                     /evalue="9.40E-11"
                     /label="ctg111_4_PP-binding.1"
                     /locus_tag="ctg111_4"
                     /protein_end="328"
                     /protein_start="267"
                     /score="34.0"
                     /tool="antismash"
                     /translation="DCIAEVLGYTDFGITTDIYEAGLTSITAIKLNILISKAFDIVIKT
                     SDIKNHPTIRMMEEFV"
     CDS_motif       complement(6621..6683)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_4_0003"
                     /evalue="8.60E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg111_4"
                     /protein_end="168"
                     /protein_start="147"
                     /score="33.9"
                     /tool="antismash"
                     /translation="IGRKDSQVKIRGFRIELSEVE"
     CDS_motif       complement(6780..6866)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_4_0002"
                     /evalue="1.10E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg111_4"
                     /protein_end="115"
                     /protein_start="86"
                     /score="40.1"
                     /tool="antismash"
                     /translation="PPGACGELMITGWQVSRGYLNKPEKTAEV"
     CDS_motif       complement(6969..6995)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_4_0001"
                     /evalue="4.30E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg111_4"
                     /protein_end="52"
                     /protein_start="43"
                     /score="7.0"
                     /tool="antismash"
                     /translation="YGPTEATIF"
ORIGIN
        1 acacctgttt tttacgacat tgaaaccacc ggattatcaa gaaattccac gtatttatac
       61 ctgattggag ctgttggaat tgaagatgaa acttggaatt tttatcaatg gatggcggaa
      121 aatgcaaatg aagaagagac aattctgaga attttttcac aatttcttca gcaatgtgat
      181 ttgctgattt cctacaacgg agaccgcttc gaccagccat atctggaagc acgatatgaa
      241 aaatatggaa tcccctctcc atttacagga aaacagtctc tggatctcta cctgacatta
      301 aaaccgttaa agtcactttt gaaactgcct gccatgaagc agccctgcat ggaagaattt
      361 ctgggaatca aagacaggat ctatgataat ggcaaggaat gcattaaact ttacaaagat
      421 tttctgaaaa aaagagatgc ctttacagct gatgaaattc tggggcacaa cctggaggat
      481 gtgctgggac ttggaagaat ctttgatatg ctgggatatc tttgcatcta tgatggagat
      541 tatgaagtta catacagtga atttgacgga gacaacctga tcctgaaact gaaactcccc
      601 tgcacactgc cacaggaatt ttccaatgga aacactgact tctatctgac aggaaaagac
      661 gaagaaatca atttaattat caaaacaact gacgggaaac tgaaacaata ctatgcagat
      721 tataaggatt actattatct cccggaggag gatacggtta tcccgaaatc tctcggatcc
      781 ggaattgaca gaaaacaccg gaaagcagca accagaaata cctgttacac ctggtttacc
      841 tgctccgatg ccttcctcag ttctcccgta cagcagaagc aatatctgac atatacgctt
      901 tcctgtctga ttggaactct agaacgtgtc tgaaaaatcc tctgtgatca tatataaata
      961 tcgtcaaaag caatttccaa tggattgtga agagaaaaag ccctctcact gctgactgag
     1021 aaaatataac cgtcaaattc cattgtctca aaaaagcatg gcctttctga ggattttccg
     1081 aggacaaacc catctgctgt gggaaccact tcaaaagaat ccaaaggaag gctcattcct
     1141 ctgcctgtca ttttcatata actttctttt aatgtccaga gcgtaaaaaa cgccttatct
     1201 ttgttcttcg cagccttgat gtaagcaagc tctgaatggt agaaataatg ttctgccacc
     1261 tcaagaggcg cattggcatt tttctcaata tcgcacccga cttcgcagtc tgacagcact
     1321 cccacaacat agtcccccgc atgagataca ttaaaaaaaa ggccatccac aaccggcttt
     1381 tcattgtcag aatatctcag gcagctttcc gtaagcccgt tttcatcgag gatttttctg
     1441 atgatgattc ctgcacccag acttcttttg cggtcatcag gcatacgata cctgatgacc
     1501 ttttctcttc ttctgatccc aaccagatcc agaagccttt cattcttaag cggatcctca
     1561 aaatgattaa tattgatcct gtataatttc tgcatctgat caacagttac ttcttctgaa
     1621 tatcgatctt gctgtcaaac cctgtaaggc tgaatacatc gtaaacctca tcagaaacat
     1681 tgatgatctt aaatccatcc ttttgagcca tttttttgta ggctacgatc acctgacgta
     1741 agcctgcaga tgaaatatac tccagatttg taaaatcaaa taccagactt gtgatgctgt
     1801 cttcaagtcc ggacagagcc tcccctaact ggggagctgt ctgtgtatca agccatccgc
     1861 tgatttccat agttgctttg ttaccttctg tttttgtgat aatttccatt gtgattttcc
     1921 ctcctgaatc aatcaaaaaa tgtaagtctg tcaagtgctg caattgcatt ttccagatat
     1981 ctgtcatctg taaccggcca tttataatcc agcctgtaca gaacctgtgc tgtaaaacga
     2041 ttgctgtaat caatggtata gatttcattt tcattatgtg aggtataggc gatcagtccg
     2101 gaaaccgcat cagaatcctg accggtcttt gcaaattcct tcactgctgc ctcaaactcc
     2161 tcatctctta caatatcaat cctgaatcca tagctgcgca ttgcgtagat caggtctgcc
     2221 atataaatat gatggctgtt gcatgcatga aatacagtaa atctccggtc ggtctgagcc
     2281 agtctcagaa ctgccagcgc agtagaatca atcggtgaga attctgccac ctcatgcata
     2341 ccgcccatag ggaatttacc tacagccaca taacctctca ggctgcgaag gaatccattg
     2401 gtaatgaaat taatctggaa ctcaccgtca gagtttcggc tcatcagatt acctacccgg
     2461 actaccttgc cgtccagtcc ctcggaaact gcttccagaa ccgccctctc tgccaggaat
     2521 ttggtgcgga tatattcgtt ggtaatattc tgtccgatgt acagatcatt ctcacagaaa
     2581 actctggaca ttggcggaac accgtcagaa ccttctcccg caacggaaac cgtagaaatc
     2641 tggatcagtc tgcggccgtt attcttacag aaatcgatca gattttccac accctgcaca
     2701 ttaattcttt ccagtacatc atcagccgca aaatgcttta cgcaggcagc gcagttaatg
     2761 atggtgctga atttgtattc tgaaaatcct gttacctgtt cctttgaggt aatatcccca
     2821 tccacacaga taatacggct ttcaaacagc tctttgtatg gatcatcaaa atagtacatc
     2881 agcatgttca tcattcgctt ttcaggcgat tcatatttgc ccttacgtac aagacagtaa
     2941 accttaccgt cataattgtc aaggaatgct ttaaggacat ggatccccag gaaacctgtg
     3001 gcacctgtga ccataatatc tcccagcttt tcctttgtga tccggtctgc attttcttct
     3061 gtatttgcgc tgatcacatt ctggatcctg ttatagttat aatccgaaaa ttcattcttg
     3121 ctctgtgcag cctctgtaac tccgtcatca tcaaccaaag ctgcaagttc ccgtacagta
     3181 ggatatttga aaatatccgc atataccagt gaaatattct ttgacagaca cataacagca
     3241 accttggatg cagtaaggga agatccgccc agctcaaaga agttgtcctc aatccctact
     3301 ctttcaattc ccagtgcttt ctcaaaaatc tcacagagtg ctctctgagc tgcagtaacc
     3361 ggctctacat agctggcagt gttcgtggtt acctccggca ttggcagtgc ttttttatca
     3421 atcttaccgc ccggtgtcac aggcatttcc tcaatgctga caaagaaaga cggcatcata
     3481 taatccggga tcagcggctc caggaaggtc ttcagttcat cctccgggat ggcttctcct
     3541 gtataataag ctgtgatata tttatttcca cccttttcaa ttactgtaac ggctgcattt
     3601 ttcaccagct catgtttcag aagggcacct tcgatctcac caagctccac acgatatcct
     3661 ctgatcttca cctgtgaatc gatccggcct atgtactcaa tatttccgtc acctttcatg
     3721 cggaccatat caccggtcct gtaaagacgg ctttcctgct cacatacagc aaatggattt
     3781 tctacaaaca cagatgctgt tttttccgga agattatgat atcctctggc aatctgcctt
     3841 cctgcgtgac aaagttcgcc ggacgcaccc accggaagcc ggttcagatt ctcatccaca
     3901 atgtagctgc gcacattccg ctgtgatttt ccgatcggga tgttgtcata ctgtctgtct
     3961 accaaaaact ctgtggaaga aaccgtattc tctgtaggac cgtagccatt gatcatctga
     4021 taggtacggt tacggtaatg cttgaatttc tcgccgccaa gtgtaacaaa tttaagagca
     4081 ggtgcatcct ccagaagttc tgtaaccagt tctcccatct gggtagggaa ggttacggtg
     4141 gtgatctctt tttcctttat atatctgctt atggcaatgg cgtccttacg gatactctcc
     4201 ggtaaaatat acaggactgc tcctgcggta agaggtgcaa acagatcgat cactgacgca
     4261 tcgaaacaga agctcgcaaa ctctgccaca atgtcatccg gtgaagtatt tctgctcagt
     4321 gtgatatatt cgatcaggtt caacagattt ctgtgctcga tcataacacc ctttggcttt
     4381 cctgtggagc ctgaggtata gatcatatag gcaaggttct ccggtttcgg agaaataagc
     4441 tctgcagaaa gttcaaaatc ctcagcctca tctggcacac tgtccagact gatcacattt
     4501 ccgtcataaa attccacaag attctgatac tgatcgatca caaggagatt tcttgctcct
     4561 gaatccttca gcatatattc aattctgctc tgtggatact ccggatccag aggaacatag
     4621 gctccgccgg ccttcataac acccacatag gctactgtat attcttttgt cctgccgcac
     4681 aggatacctg ctgcctgttc cgggccaaat ccgttttccg taagcttctg agcaatataa
     4741 tcagacattc tgtccaactc tctgtaagta aaatctccgg agtcatcccg cactgccggt
     4801 ctgtccggat atctggcagc catctcctta aacagatcta tgaaggtctt tcctgcatgt
     4861 tccggaatat cctccatctg agttttttcc tcaaacatca gccggatatc agccggatcg
     4921 cattccctta agattccctc tgcagtggtt tccagattgt cagccagata ccggatagtt
     4981 tcctcatggt acatatcccc tctgtactca atctcaaaga caaatctgtt cttttcaatg
     5041 gaaatgctga cagaaaccgg tgcctttgcc atgttcaggc tgacaggctc ctcctgtgca
     5101 tattccccgc caatggtgtc aaaagcaaaa ttgtcgccct ggtaaataac catggcatct
     5161 gccttaatat caaactcatg gctgatctgt gagaaaggat aaatatcgtt gttcatggaa
     5221 tcgatcagct gtttctgtac accgcttaag caatctttgg ctgttcctga gaaatcgcag
     5281 aaaacaggga gtgtttttac cagcataccc actgtttccg aaagtctgga atcgtttctt
     5341 ccatggtaaa tagtggtaaa tacagcatcc tttttgaaat tatattttcc aagtgtgata
     5401 ccaaaagcgg aaatgaagaa tacattctcc gtaattccat gctttttaca gaattccttc
     5461 acattctgca cggaaatgga tctggtctct ctgtggtaaa gttctgctgt tggagccgca
     5521 ccgtttttgt ccggatagaa gctgatgctt ccacctgcat gttcaaatac tgacttataa
     5581 taattctctg catttttata gatatcacct gccagggcat ctctgttatc cagtgccaga
     5641 tcataggaag tataaccttc cggttccagc ttctcaccgc tgtaagctct gttaatatca
     5701 ttaattataa tagccagaga tgtaccatcg gcaacaatgt ggtgaaggtc caggaacaga
     5761 taattgccat cacaggttct gtagatttca aaccggaaaa gctgttcatt aaacaacata
     5821 tatggacgta ccagagtgtc tctgttcatt ccgtttaaaa tcggtgtttt ataactgagc
     5881 ccatcgtttc gtttctgaag tacatttccg ttgtcatcca taaacagacg ggttttcaga
     5941 taaggatgtg cctcaacagt actgtcaatg gcttctgcca gtctgtccag atccaccttg
     6001 ttatcaagct ttaacagata cgggatattg taaatggtag aacccatatt tgcagtacac
     6061 tcaatgaaaa tcccctcctg agtgttggta agaggataac tttcctgtac ttcccttttg
     6121 ctttcttttc ccgcagtttt tacaaattcc tccatcattc ggatagtagg atgattctta
     6181 atatctgaag ttttgatcac aatgtcaaag gctttggaga tcaggatatt cagcttaatg
     6241 gcagtgatag atgtcagacc tgcctcataa atatctgtgg taatcccaaa atccgtatac
     6301 cccagaacct ctgcgataca gtcaaataat atctgctgaa cctcattctc aggcttaatg
     6361 atctccgctg cttttttctc aggcagagga agagcctttt tatttacctt ctggttctgg
     6421 ttcagaggaa ttttgtcaat ctgcatggta actgcaggta ccatataggc aggctttgtc
     6481 tctttaataa aatcattcag ggcattgata tcaacagtgc tgtccgatac cacataggca
     6541 gcaatatatt ttccaccatt tggatcatca aaggcaacta cagtggcatc cctgatgccc
     6601 tcatatctgc ggatcacttc ctcaacctca gaaagctcaa tcctgaaacc tctgatctta
     6661 acctgggaat cctttctgcc aatgatctgg atatttccat ccggaagaaa tcttgccaca
     6721 tcacctgaat gatacatcac ttcgtatccc ggtgtatcat cataaagatt ctttgtatag
     6781 acctcggcag ttttttccgg cttgttaaga tatcctctgg aaacctgcca gccggtgatc
     6841 atcagctctc cgcatgcacc gggaggaagc atatgcccca gcttgtctgt aatataaagc
     6901 ttcacattgt caagtgcttt tccgatcggg acatttggat aatatttgcc cacttcaaat
     6961 acagtcgtaa aaatagtcgc ctctgtaggt ccataagcat tgataaactt ataatctttt
     7021 ggcgcctcac atggaaccat tttctctcct ccaacagaaa gatatctcag gctcttacaa
     7081 tccatctcca gcgcaaactg ccttcccacc tgagtagtca taaagg
//
