LOCUS       c00039_gnlPro..        16332 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BEKALDCJ_39.
ACCESSION   c00039_gnlPro..
VERSION     c00039_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 00:26:25
            Original ID  :: gnl|Prokka|BEKALDCJ_39
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 303237
            Orig. end    :: 319569
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16332
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[313237:316230]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12993
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16332
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16332
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             303..1127
                     /locus_tag="ctg39_311"
                     /transl_table=11
                     /translation="MVYKIMYPPIPNMGDLLNKDMLEELFNIKVVRKDLKSCNLIAIGS
                     ALDHIMYSTYPRIRAKQKIEHFMNDNVHIWSTGFIRGNAELDLGLMFRHIHIHALRGRL
                     SLQRMENILGKKLDVPTGDGGLLAERWLGFYPEKKYRVGIIPHFKEQDHPVVKKLLDNY
                     ENSTLIDLKENPKKVVEKIGECEYIISSSLHGMIVADSFHIPNMHITLTNNMFGDGNKY
                     NDYLSAFDITHTPFDCSNGDMPTISEVKNNYRIDPDVVELKKEQLFNAFPKF"
     CDS             1151..2695
                     /locus_tag="ctg39_312"
                     /transl_table=11
                     /translation="MKKLSTSKQMAINMVAAIVSFLIGTGINFVLAPYLVKELGSETYG
                     FIGLANNFVQYATIVTSALNSMSGRFISIEYSKGNIDKASRYFSSVLVADLIIAGVLLL
                     VSSIITFNIEFILNVPENLVDSVKILFALTFATFIISVITAIFTTAAFVKNKLYINSLR
                     DIASNTLKLLLVVILFSFFPAKVYFLAMASLASGIFLLLTNIKVKNKILPEVKMNFNLF
                     SFKLVKVLISAGIWSSIGYLSTALNRGLDLLICNLTLGAGLMGLLSIANTVPHCIDNLI
                     TTIANIFTPRFTILYAKDNTDLLVEETKFSSKIMSFLMTAPLAGFIAFGNKFYTLWQPT
                     KSPDEITIIQILSVLVCISYLFTCHTRTLSSLFTVCNKLKASVLISLVCGVLTVIIVLL
                     LIHFTPLGVYAIAGVSSVFIGLKAIVFVPLYAAHILKIKLTTYYRSIFRGWFCFAVVIT
                     MFIFINSFVHANSWMSFLLLCAASGLAGYAVSVPLIFSRKELVLIKDKIKKKFKKS"
     CDS             2719..3633
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_313"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.1e-29,
                     bitscore: 97.8, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEYTFSVFTPSYNRAKTLPRLYEALKKQTYRNFEWIIVDDGSAD
                     NTKETVEKFISDRPDFNITYKYQTNKGKHIATNVAAQIAKGEFFITIDSDDSVKDDALE
                     TFINEWNKIPDEDRSKYKGISCRTCNESGKTNGCPLPSERFDCSDLDLRLKYKIDGEMW
                     GMTKLEIIRANPYPCVSGLHFYPENIYWDNIGRKYITRFIDTPLRYYINDQENSLTGNA
                     YSAHRETIFVRLHFINECWDYAKSNPKFFIKQFVGLSRDGLLNGKRFSEIKKMPDTFSK
                     RALAVIFYPMGYFLYKKQSGGSR"
     CDS             3633..4712
                     /locus_tag="ctg39_314"
                     /transl_table=11
                     /translation="MKKVGIVTFHRALNYGAVLQSYALQKTVSSLGAECEIVDYICPKI
                     TADYKPFRIYKNDLLKSFAKSCVMVRRRAKRRDAFKSFFNNYLVKSKKSYTPQNIRELK
                     NDYDLFISGSDQVWSPRCVGFDPAYFLTFADDKQKYSYAASFAVPTLPDEFIDEYKKRL
                     NGFQKFSVREPSGEKLVKELTGRTAETHLDPTLLISADEWKKIAVSKIDKPYILIFTAN
                     PAVSLVDFAIKLSKEKNLPVYCINDAPHPVSHGINYIVAPTVEEFVGCFKNAEYVVTNS
                     FHGTAFSVIFNKNLFVEFKNKSGRNIRSEGLLKSLGINREIVDGNCRETEINWYDVNEK
                     IKNQTIISLDYLKSFVSGG"
     CDS             4714..4872
                     /locus_tag="ctg39_315"
                     /transl_table=11
                     /translation="MSLKNTLKKVRQGIIKTFKAKNVVPVYVQKENNNILDGKTALITG
                     GSGIIKN"
     CDS             4888..6651
                     /locus_tag="ctg39_316"
                     /transl_table=11
                     /translation="MYSTIKSIQLLTALLKKYNINKLVLSPGGSDIPIIHSLENDDFFE
                     CHSVVDERSAVYYGIGLAQQTKSPVACICTSGTAVSNYLPGMTEAFYQDVPIVAITADK
                     DPYRLNQLMLQKTQQVNIFESVTKKSVNLPVVRGGNDRWYCERLINEALSELDHHGTGP
                     VHINIPIVENSAVYDCENLPQVRKINRISPDMPSEKWREYAERLSKYKKILVIAGQNNC
                     FSEDDRACVEKFFEKYNCLISVEHMSNLKCKGCLMTYPLSECSMQGMFGELCPDLIISF
                     GNNIASYKLKPMIKAHKEKFVHWQIDTAGRIRDFSDKLTDVFECTPQYFFNCFAENAPQ
                     NSKNDMTYYNMWNDDIKMLDYSSNLPFSNMYVAKKLAEIIPDRSVLHLAILSSTRTMQF
                     FDLKPNVKVYSNIGALGIDGCMSSFFGQASATDELAFCVVGDLSFFYDMNSAGIRGIKN
                     NARIILLNNGGGSEFHFFMGKEKIPTINQYICAEHHKGAKGWIESLGYDYYSATTKEEV
                     DNIIPTLAEESDRPIFVEIFTDMEEDAKLINRLFHDNRMKFGGMKLKMMEKAKSILSPS
                     QIQKAKKLLKK"
     CDS             6666..7850
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_317"
                     /sec_met_domain="UDPG_MGDP_dh_N (E-value: 1.9e-36,
                     bitscore: 119.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="UDPG_MGDP_dh (E-value: 5.7e-28, bitscore:
                     91.4, seeds: 679, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAIAGTGYVGLSNAVLLSQKHEVTAVDVVESKVKLINEKKSPI
                     ADREIEEYLADKKLNLVATVDAKSAYKNADFVIISTPTNYDDERHFFDTSSVEAVIKLV
                     IECNPNAVIVIKSTIPVGYTKSVIEKYKYTKILFSPEFLREGKALYDNLYPSRIIVGVD
                     MANEELKKSAETFATALADCAIKENIDTLFMDYTEAEAVKLFANTYLAMRVSFFNELDT
                     YAEMKNLNTKSIIDGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLKANFSDVPNDIISA
                     VVTSNKTRKEFITSQIMNKNPKAVGIYRLTMKSNSDNFRQSSIQSVMELLKNNGIELII
                     YEPTLKVDLFEGFGVENDFEKFVTKSDVIVANRYSSVLDCVKEKVYTRDLFFRD"
     CDS             7866..9017
                     /locus_tag="ctg39_318"
                     /transl_table=11
                     /translation="METLIIGKPKIEKLDNRARLCSKISENGKPSYTLWFDVDTKYADY
                     LTESADAFVVALLPYAMNNSLNISAEAKMSKQLCFQLNEIFIPVLTKNSKLFNKISISA
                     KELTQENYCCKNASATGFSRGVDSFDTICSLSENRTEKLSHLTFFNVGSHRSTANYTPE
                     QSAELYENRLEIAKKSAKIFDMPLIDINSNLGEHLTLPYVKVHHYCSFSAVLCMQKFFK
                     NYYYASGYPISSFSIKQCDTGSAHYEAFTASMLSTESTDFYITGLEKTRLEKVDFISKF
                     PITYDNLNVCYYGENNCGHCEKCVRTQFELMLLGKLELYKNVFDIPKFYRDKNKYMDYV
                     LKHQNKDYYAEILSLMKKKGFKLTPIQKIKKAVYAIYLKFREN"
     CDS             complement(9238..9456)
                     /locus_tag="ctg39_319"
                     /transl_table=11
                     /translation="MDKNKKLFYTIIGAISALAAATAAFLALKKHRCAEQKLIEEIDDI
                     VSEKEPEEAAKEEPLAEVTADELAEEE"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 76.2;
                     E-value: 1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_320"
                     /sec_met_domain="Radical_SAM (E-value: 2.4e-29, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNAVKGFVHSIETFGSVDGPGVRFVIFLSGCAMRCQFCHNPDT
                     WKHDENTVEYTADELLNKALAYRPYWKNKGGITVSGGEPLLQIDFLLDLFKKAKKQGVN
                     TCIDTSANPFTTKEPFYSKWKELMEYTDLLLLDIKHIDNEQHKILTGQPNTNILEMARQ
                     LSDMGKPVWIRHVLVPERNDKDEYLFRLADFIRSLKNVERVEVLPYHTLGVYKWKALGY
                     DYPLEGIEPPTKERVKNAEMILNGEKTRD"
     CDS             complement(10756..12993)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_321"
                     /sec_met_domain="Gly_radical (E-value: 3.4e-40, bitscore:
                     131.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.7e-270, bitscore:
                     892.9, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEWTNFAGGKWESDIDVRDFIQRNYTPYDGDQSFLEGPTEATD
                     KLWGELKELQKEERAKGGVLDMETEVVSGITAYGAAYLDKDLEKVVGLQTDKPLKRAFM
                     PYGGIKMAEQSCQMYGYTPSPKLHEIFTKYHKTHNQGVFDIYTPEMKLARHNKILTGLP
                     DTYGRGRIVGDYRRVALYGIDRLIEGKKEDFAETNRQGMRRGDFQLREEIADQIRALND
                     MKEMALSYGFDISQPAKNAAEAVQWLYFGYLAAIKTQNGAAMSVGRVSTFLDIYIERDL
                     ENGTLTESQAQELVDHFVMKCRMVKFARIESYNQLFSGDPVWATLEVAGLGIDGRSMVT
                     KNDYRFLHTLENMGPSPEPNLTVLYSSRLPENFKKYAAHISVTTSSIQYENDDVMRPVW
                     GDDYSICCCVSATQTGKEIQFFGARANLAKCLLYAINGGIDEKTKMQVGPEYTPITSEY
                     LDYDEVIKKYDTMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTDVRRTFATGIAG
                     FSHVVDSLSAIKYAKVKVIRDEDGVAVDFETEGDFPRYGNNDERADKIAVDLLKTFMAK
                     LKYCHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQNGLLA
                     SLNSVAKLPYEYALDGISNTQTINPGALGHNDDERVDNLVNVMDGYFDQGAHHLNVNVF
                     GTEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             complement(13260..13751)
                     /locus_tag="ctg39_322"
                     /transl_table=11
                     /translation="MKTDRVITAMIEYFGSDKKRIHHFLKVYSFAKTIGESENLLPDDQ
                     ELLEISAIVHDIGIKVSEEKYNSSAGKYQELEGPHEAEKLLAALGYEKTFIDKVCYLVG
                     HHHTYGNIDTLPYRILVEADFLVNLYEDDSSRSAAEQAYDKIFRTNTGKNLLKIMFLIP
                     "
     CDS             complement(13870..14406)
                     /locus_tag="ctg39_323"
                     /transl_table=11
                     /translation="MVIIMAHPIKHFRTITRHRHKVIANCARAGILRQGLIHDLSKYSP
                     TEFIPGAKYFQGTRSPNEKERELYGYSQAWLHHKGRNRHHYEYWNDYNPKTKQIENVEM
                     PVKYVIEMFCDRVAASKIYNGKNYTDGAPFTYFCRIRGKHRMHPNTEALLEKLLVMLRD
                     EGEEKTFAYIRSMKK"
     CDS             14571..15758
                     /locus_tag="ctg39_324"
                     /transl_table=11
                     /translation="MKKKIFILLLCVVLIATCILCGVTGIFGNDSQNSPKPQTHDTAVT
                     ENMTFPSKVDSLTLKVGESKLIELSSEKAKSVTKWTSSDSKIVTVDDGGRVDALKEGTA
                     LISAISKDKSKSEFQVTVAKSTTKKQQSYSTCITANLDKLENNKRNTAKNLYAIKVNRT
                     ANCVTVYTYDEKGKYTIPVRAMICSTGLDNSTITGDYTIGIKSEWLSLVGDVFGRYISG
                     ISGDYLFHSVPYYSMSEEDLELEEFNKLGEQASQGCVRLAVSDAKWVYDNCPTGTNVSI
                     YDDAENAGPLGKPDAIKITDFTNKWDPTDSNKKCPYAKATPIISGANDYTIKSGGEFYA
                     LAGVTAVDTCGNDITSNIEVFGNVVTTRKGKYKVTYSVTDVLKRTSSVTITVTVQ"
ORIGIN
        1 tctaccaata cctctttgaa ggcggaattg tattcggact tattccggta tattcaagcc
       61 tttcgctgac ggcaaaggtt gtatgcacaa gaatcaaaga taagtcagaa tttgcgttgt
      121 gctgtacgct tgtgtgcgta acacttccaa aacttctgat ttccaccgaa ccatgggcaa
      181 caacatcgat atggatgctt attacttatt cgctgatata catatgcaag acaaatccga
      241 tatttatatc tcttaatcag agcttctgct cacggcgcaa ataatacaac ggagaaaata
      301 caatggtata taagataatg tatcccccga ttccgaatat gggagatctt cttaataaag
      361 atatgcttga agaactgttt aacatcaagg ttgtaagaaa agaccttaaa agctgtaacc
      421 tgattgcaat cggttctgca cttgaccaca taatgtactc aacatatccg aggatcagag
      481 caaagcagaa aattgagcat tttatgaatg ataatgtcca catatggagt acgggcttta
      541 tccgaggcaa tgccgagctt gatttggggc tgatgttcag acatatacat atacacgctc
      601 tgaggggcag actttcattg cagagaatgg aaaatattct cggcaaaaag cttgatgtgc
      661 cgacaggtga cggaggactt cttgccgaaa ggtggcttgg attttatccc gaaaaaaagt
      721 atcgtgtcgg aattatcccg cactttaagg aacaggatca ccctgttgtg aaaaaacttc
      781 ttgataacta cgaaaattca acgcttattg acctgaagga aaacccaaaa aaggttgtcg
      841 aaaaaatagg cgagtgcgaa tacattattt caagcagcct tcacggtatg attgttgccg
      901 acagtttcca cattcccaat atgcacataa cccttacaaa caatatgttc ggtgacggaa
      961 acaagtacaa tgattacctc tccgcctttg acattacaca cacacccttt gattgttcaa
     1021 acggcgatat gcctacaatc agcgaggtga aaaataatta cagaatcgat ccggatgttg
     1081 ttgaactgaa gaaagaacag ctcttcaatg cttttccaaa attttaatca gttaaaacta
     1141 aggtcatatt atgaaaaaat tatcaacaag taaacaaatg gcaataaata tggttgccgc
     1201 catagtgtct ttcttgatag gaacaggaat taactttgtt cttgcaccct atcttgtaaa
     1261 ggaactcggt tctgaaacct acggatttat cggacttgca aacaactttg tccagtatgc
     1321 caccattgta acatctgctc tcaactcaat gtcgggcaga tttatttcaa ttgaatacag
     1381 caaaggaaac attgacaagg catcaagata tttcagctcg gttctggttg ccgacctgat
     1441 tattgccggc gttttacttt tggtttcgtc aattattaca ttcaacattg aatttatact
     1501 gaatgttccc gaaaatcttg ttgacagcgt aaagatattg tttgcgctca cttttgcaac
     1561 atttataatc agcgttatca cggcaatatt tactactgcg gcatttgtaa aaaacaagct
     1621 gtatatcaat tccctccgtg atattgcgtc aaatacgctc aagctcttgc ttgtagtaat
     1681 tttgttctcg ttttttcccg caaaagtata ttttctcgct atggcgtcac ttgcaagcgg
     1741 aatttttctt ttgcttacca atatcaaagt caagaataaa attctgccgg aagtaaagat
     1801 gaacttcaac cttttcagtt tcaagctggt aaaagttctg atttccgcag gaatttggtc
     1861 gtcaatcggt tatctcagca cagctctgaa cagaggtctt gacctgttaa tctgtaacct
     1921 gactctcgga gcgggactca tgggactttt gtcgattgca aacaccgttc cgcactgcat
     1981 tgataacctt attacaacca ttgcaaatat attcactccc agatttacaa tcctttatgc
     2041 aaaggacaac acggacttac ttgttgaaga aacaaagttt tcgtcaaaga ttatgagttt
     2101 tctcatgact gcacctcttg cgggatttat tgcgtttggc aacaagttct atacattgtg
     2161 gcagccgacc aaatctccgg acgaaattac cataattcag attttgtcgg tgcttgtatg
     2221 tatttcatac ctatttacct gtcacacaag aactctttct agccttttca ccgtatgcaa
     2281 caagctcaag gcctccgttc ttatctcgct tgtgtgcggt gttcttacgg ttattatcgt
     2341 tttactgctc atacacttta caccgctcgg tgtttatgct attgcaggcg tcagctctgt
     2401 ttttatcggt cttaaagcga tagtatttgt tccgttgtac gccgcacata ttttgaaaat
     2461 aaagcttaca acatattaca ggtctatttt caggggatgg ttctgctttg ctgttgttat
     2521 caccatgttc atctttatca acagctttgt acacgcaaac agctggatgt cattccttct
     2581 tctctgtgca gcaagcggac tggcaggata tgccgtttcc gttccgctca ttttctcaag
     2641 aaaagaactc gttcttatca aggataaaat taagaagaag tttaagaaaa gctaaattat
     2701 tatcattttg aggttgcaat gactgaatat actttttccg tttttacacc gtcatataac
     2761 agggcaaaaa ctctgcccag attatatgag gcgctgaaaa aacagacata cagaaatttt
     2821 gaatggataa ttgttgatga cggttcagcc gacaacacaa aagaaacggt tgagaaattc
     2881 atcagcgaca gacctgactt taacataacc tataaatatc agaccaacaa aggaaaacac
     2941 attgcaacaa atgttgcggc acagattgca aagggtgaat tctttataac gattgactcc
     3001 gatgacagcg taaaagacga tgcccttgaa acatttataa acgaatggaa caaaattccc
     3061 gatgaagaca gatcaaaata caagggaatt tcgtgccgca cctgtaacga aagcggcaaa
     3121 acaaacggtt gtcctctgcc gtcagaacga tttgactgtt ccgaccttga cctgagattg
     3181 aagtataaaa ttgacggtga gatgtgggga atgacaaaac ttgaaataat cagagccaac
     3241 ccttatccgt gtgtttcggg acttcatttt tatcccgaaa atatctattg ggacaatatc
     3301 ggaagaaaat atataacccg ttttattgac acaccgttgc gatattacat aaacgatcag
     3361 gaaaattctt tgacgggtaa cgcttactcg gctcacaggg aaactatttt cgtaagactc
     3421 cactttataa acgaatgttg ggattacgca aagagcaatc ctaagttctt tatcaaacaa
     3481 tttgtgggac tttcccgtga cggcttactc aacggtaaaa gattttccga aataaaaaag
     3541 atgcccgaca cattttcaaa gagggctctt gcggtcatat tttatcccat gggatatttt
     3601 ttgtacaaaa aacaatcagg gggaagcaga taatgaaaaa ggtaggcatt gtaacatttc
     3661 accgtgcatt gaactacggc gctgtgcttc agagctatgc gttgcaaaaa accgtttcat
     3721 cgctcggtgc ggagtgtgaa attgttgact atatctgtcc gaaaatcaca gccgactaca
     3781 aaccctttcg catttataaa aacgaccttc tgaaatcctt tgcaaaaagc tgtgtcatgg
     3841 taagaagaag agcaaaacgc agagacgctt ttaagtcgtt tttcaataac tatcttgtaa
     3901 agagtaaaaa gtcgtatact ccgcaaaata tcagagagct taaaaacgat tatgacttgt
     3961 tcatttcggg aagcgatcag gtatggagtc cgagatgcgt cggttttgat cccgcttatt
     4021 ttctgacatt tgccgatgac aaacagaagt attcatatgc ggcaagcttt gccgttccga
     4081 cattgcccga tgaatttatt gatgaatata aaaaaaggct gaacggtttt cagaagttct
     4141 cagttcgtga accgagcgga gaaaagcttg taaaagaact cacgggcaga accgccgaaa
     4201 ctcatcttga tcctaccctg ctgatttcgg cagacgaatg gaaaaagatt gccgtttcaa
     4261 aaattgacaa accgtatatc ctcattttta cggctaatcc ggcagtttcg cttgtggatt
     4321 ttgccattaa actgtcaaaa gaaaagaacc ttcccgttta ctgcataaac gatgcacctc
     4381 accctgtaag tcacggtata aattatattg ttgcacctac tgttgaggaa tttgtcggct
     4441 gtttcaaaaa tgccgaatat gttgttacaa actcgtttca cggaacagcg ttttctgtta
     4501 ttttcaacaa gaatcttttt gttgaattca agaacaaaag cggaagaaac atccgctccg
     4561 aaggtctttt gaaaagtctt ggaatcaacc gtgaaattgt tgacggaaac tgccgagaaa
     4621 ccgaaataaa ctggtacgat gtgaacgaaa aaatcaagaa ccagacaata atatctttgg
     4681 attatcttaa atcctttgtc agcggtggtt aaaatgagtc ttaaaaatac actaaaaaaa
     4741 gtcagacagg gcataatcaa aacctttaaa gcaaaaaatg ttgttcccgt gtatgtgcag
     4801 aaggagaaca acaatattct tgacggcaaa accgctctga ttacaggcgg ttccggaatt
     4861 atcaaaaact aaagcggagg aaagcgtatg tattctacaa taaaaagcat tcagttgctc
     4921 actgcacttc tgaaaaaata taatatcaac aaattggtgc tttctcccgg aggcagtgat
     4981 attcctataa ttcattcact tgaaaatgac gatttttttg agtgtcattc ggtcgttgac
     5041 gagagaagtg ccgtgtatta cggcatcgga cttgcacagc agacaaaatc ccccgttgcc
     5101 tgtatctgta cctcgggtac ggctgtaagc aactatcttc cgggtatgac agaggcattt
     5161 tatcaggatg ttccgattgt cgcaattacc gctgacaaag acccgtacag attaaatcag
     5221 cttatgctgc agaaaaccca gcaggtcaat atttttgaat cggttacaaa aaaatccgtt
     5281 aatcttcccg ttgtgcgtgg cggaaatgac agatggtact gcgaaagact tattaacgag
     5341 gctctttcgg agcttgacca tcacggaaca ggacctgtgc atatcaatat tccgattgtt
     5401 gaaaactcgg ctgtatatga ttgtgaaaat cttcctcagg ttaggaaaat caacagaatt
     5461 tctcccgata tgccctccga gaagtggcgt gaatatgcag aaaggctttc aaaatataag
     5521 aaaattcttg tcattgccgg tcagaacaac tgtttctcgg aagatgacag agcgtgcgtc
     5581 gagaagttct ttgagaaata caattgcctt atatcggttg agcatatgtc aaacctcaag
     5641 tgcaagggct gccttatgac ctatcctttg tcagaatgct caatgcaggg aatgttcggc
     5701 gagttatgcc ccgatcttat tatttcgttc ggcaacaata ttgcttcata taaactcaag
     5761 cctatgatta aggctcacaa ggaaaaattt gttcactggc aaattgatac tgcgggaaga
     5821 atcagagatt tttccgacaa gctgacagat gtatttgaat gtacaccgca gtatttcttt
     5881 aactgctttg cagagaacgc accgcagaat tcaaaaaatg atatgacata ctacaatatg
     5941 tggaatgacg atatcaaaat gcttgattat tcaagcaatc ttccgttctc aaatatgtat
     6001 gttgccaaaa agcttgctga aattattccc gaccgttctg ttctgcacct tgcaattctc
     6061 agcagtacaa gaactatgca gttcttcgat ttgaaaccga atgtcaaggt ttacagcaat
     6121 atcggcgctc tgggtattga cggctgtatg tcttcgtttt tcggacaggc atcggcaaca
     6181 gacgagcttg ccttttgcgt tgtgggcgac ctcagtttct tctatgatat gaactccgca
     6241 ggcatcagag gaatcaagaa caatgcgaga attattcttc tcaacaacgg cggcggttca
     6301 gaatttcact tctttatggg caaggaaaag attcctacaa tcaatcagta catctgcgcc
     6361 gaacatcaca agggcgcaaa gggctggatt gaatcactcg gatatgacta ttacagcgca
     6421 acaaccaagg aagaagttga caacattatt cccacactcg cagaagaatc cgaccgaccg
     6481 atttttgttg agattttcac cgatatggaa gaggacgcaa agcttattaa caggcttttt
     6541 catgacaaca gaatgaaatt tggcggaatg aagctcaaga tgatggaaaa agcaaagtca
     6601 attctcagtc cgtcacagat tcaaaaggca aaaaaattat taaaaaagta atcaggtgaa
     6661 accaaatgaa aatagcaatt gccgggacag ggtatgtggg tctttcaaac gctgtacttc
     6721 tttcgcagaa acacgaggta accgctgttg atgtagttga aagcaaggta aagttaatca
     6781 atgaaaagaa atctccgatt gccgacaggg aaatcgaaga atatcttgct gacaaaaaat
     6841 taaatttggt tgcaaccgtc gatgcaaaat ctgcgtacaa aaatgctgat tttgtaatta
     6901 tctctactcc taccaattac gatgacgaaa gacacttttt tgatacatcg tccgttgagg
     6961 ctgtaattaa gcttgtaatt gaatgcaacc caaatgcggt tatagttatc aaatccacta
     7021 taccggttgg atacacaaaa agtgttattg aaaaatacaa atacacaaaa atccttttca
     7081 gtcccgaatt tttgcgtgag ggcaaggctc tctatgataa cctctatccg tcaagaatca
     7141 ttgtcggtgt tgatatggca aatgaagaac tgaaaaaatc tgccgagact tttgcaacag
     7201 cacttgcaga ctgtgcaatt aaggaaaaca tagacactct ctttatggac tacacagagg
     7261 cagaggcggt aaagcttttt gcaaatacat accttgcaat gcgtgtcagc tttttcaacg
     7321 agcttgacac atatgccgaa atgaagaacc ttaacactaa aagtatcatt gacggtgtgt
     7381 gtcttgatcc gagaatcgga aatcactaca acaatccgtc ctttggctac ggcggttact
     7441 gtctgccaaa ggatacaaaa cagctcaagg ccaatttttc ggatgttccg aatgacataa
     7501 tcagcgctgt tgtaacatct aacaagacaa gaaaagaatt tattacatca cagataatga
     7561 ataaaaatcc aaaagctgtc ggaatttacc gccttacaat gaagtcaaat tccgataact
     7621 tcagacaaag ctcaattcag agcgttatgg agcttttgaa aaataacggc atcgagttaa
     7681 ttatctacga accgacactt aaagtcgatt tattcgaggg ctttggcgtt gaaaacgact
     7741 ttgaaaagtt cgtcacaaaa tcggatgtaa tcgttgcaaa cagatacagc tccgttcttg
     7801 actgtgtaaa agaaaaggtt tacacaagag atttgttttt cagagattaa tttgagggta
     7861 aaagtatgga aacattgatt atcggcaaac cgaaaattga aaaacttgat aatcgtgcca
     7921 gactctgttc aaaaatcagc gaaaacggaa agccttccta cactctctgg tttgatgttg
     7981 atacaaagta tgctgactat ctgaccgaaa gtgccgacgc attcgttgtt gcactgttgc
     8041 cgtatgcaat gaacaacagt ctgaatattt cggcagaagc aaagatgtcg aagcaactgt
     8101 gttttcagct taatgaaatt ttcattcccg ttcttacaaa aaattcaaaa ttattcaaca
     8161 aaatttcgat atctgcaaaa gagcttacac aggaaaacta ctgctgcaaa aatgcgtcgg
     8221 caacaggatt ttcgagaggt gtggattcat ttgacacaat ttgcagtctt tccgaaaaca
     8281 gaacggaaaa gctgagtcat cttacctttt tcaatgtcgg ctcccacaga agtacggcta
     8341 attacacacc cgaacaatct gccgagctgt acgaaaatcg tcttgaaatt gcaaaaaaat
     8401 ccgcaaaaat ctttgatatg ccgttgattg acattaattc aaatctcggt gaacatctta
     8461 ccctgccgta tgtaaaggtt catcattatt gcagcttttc ggcggtcttg tgtatgcaga
     8521 aatttttcaa aaactattac tatgcgtctg gatacccgat aagcagtttt tcgataaaac
     8581 aatgcgacac cggctcggca cactatgagg catttacggc aagtatgctg agtaccgaaa
     8641 gtaccgattt ttacattaca gggcttgaaa agactaggct tgaaaaggtt gacttcattt
     8701 caaaatttcc gattacatat gataacctca atgtgtgtta ctacggtgag aacaactgcg
     8761 gtcactgtga aaagtgcgtc agaacgcaat ttgagcttat gctactcgga aaacttgaac
     8821 tgtataagaa tgtttttgat attccgaaat tttacagaga caagaacaaa tatatggact
     8881 atgttctcaa acatcagaac aaggactatt atgcagaaat tctcagtctt atgaaaaaga
     8941 agggtttcaa gcttacgcca attcaaaaaa ttaaaaaggc tgtctatgcc atttatctta
     9001 aattcagaga gaattaaggc ttacggttac ttcgcacaaa acaaaaatgc atcagagctt
     9061 ttcgggcaac tgatgcattt tcttttttaa actgttttct tgaatagact gcggtggcac
     9121 accgccgaca ttattatctg ttttcaactt tcaattctta attgaaagca ccgctcgggt
     9181 atttaacttt ttcacatgca aatactgcta cccgaattgg gtgcaacaac ttgttgctta
     9241 ttcttcctca gcaagctcat cggctgtaac ttctgccagc ggttcttcct ttgcagcctc
     9301 ctcaggctct ttttcggaaa caatatcgtc aatttcctca ataagcttct gttctgcgca
     9361 tctgtgcttt tttaaagcga gaaatgctgc tgtggcagcc gcaagtgcag agattgcacc
     9421 gatgattgtg tagaataatt ttttgttttt atccattccg gcacctcttt cagtattaat
     9481 ataaatcagc ggaaaaaccg tatttttcta cttattgcta ttttatatca tatttacaaa
     9541 tttttcaata gacaactgat aatctttgca caaatggctg tcagtgtgtt atattctctt
     9601 tttacgctct gcaagggcaa aaagcactcc gcccgaaatt acaacaaaca tcataacagc
     9661 cgttgctgtc actcctgtct gaacgctgcc gtttttatca ggctgtgaag gagtactgtc
     9721 cgatgttgcg gcaccgcctg ttgccgaagt cggatttacg gaggttgtac cgacagttgc
     9781 aggctcaccc gtcggagcag tctgaacagt ctgttcctga gtagcggtcg attcttccga
     9841 cggtgacgat ttctcaacaa ggacggctta aaaatctttg aatacacctt tgattcatca
     9901 attttgctga agaaaaaaca acaaaagcag aataacaaat aaaaatcaaa acaaaaacgg
     9961 cagtaccaaa aaatcggtac tgccgttgtt atataagaaa ttaatctctt gttttttcgc
    10021 cgttaagaat catttccgca ttcttaacac gctcttttgt cgggggctca atgccctcga
    10081 gaggatagtc ataaccgaga gccttccact tgtacacacc gagtgtgtga tacggaagca
    10141 cctctacacg ctcaacattc ttgagcgaac ggataaagtc ggcaagtctg aaaagatact
    10201 cgtccttatc atttctttca ggcacaagaa catgtcttat ccatacgggc ttgcccatat
    10261 cggaaagctg tcttgccatt tcaagaatat tggtgtttgg ctgtcctgta aggattttgt
    10321 gctgttcgtt gtcgatatgc tttatatcaa gcaacagcaa atccgtatat tccattagct
    10381 ctttccactt tgaatagaac ggctctttgg ttgtaaacgg gttggcgctt gtgtcaatac
    10441 aggtattaac gccctgcttt ttagccttct tgaacaaatc aagcaaaaag tcaatctgta
    10501 aaagcggctc acctccgctt actgtgatac cgcccttatt tttccaatag gggcggtatg
    10561 caagcgcttt attaagcaac tcgtcggcgg tatattccac ggtgttttca tcgtgtttcc
    10621 aggtgtcggg attgtggcag aactggcaac gcattgcgca accgctcaga aaaatcacaa
    10681 atctcacacc cggaccgtca acagagccaa aagtttctat tgagtgtaca aagcctttaa
    10741 cagcgttgtc cgacatcaca ttctgtcgtg gcaggttctg gcaataacat ccagctgctg
    10801 ctctcttgta aggtcgatga acttaacagc ataacccgat acacggattg tgaagttagc
    10861 atactcttcc ttctcaggat gctccatagc gtcaatgagt ttttctgtac cgaatacatt
    10921 tacattgagg tggtgtgcgc cctgatcaaa gtagccgtcc ataacattta cgaggttgtc
    10981 aacacgctcg tcatcgttgt gtccgagagc acccgggttg attgtctgag tatttgaaat
    11041 accgtcaaga gcgtactcgt aaggaagctt agcaacagag ttaagtgaag caagaagacc
    11101 gttctgctct gcaccgtagc ttgggttagc accaggtgaa agtggttcgc ctgcttttct
    11161 gccgtcagga agtgaacctg tagccttacc gtaaacaaca tttgatgtga ttgtaaggat
    11221 agaagttgta ggctctgaat ctctgtatgt gtggcaatac ttgagcttag ccatgaatgt
    11281 cttgagaaga tcaacggcaa tcttatctgc tctctcgtca ttgttaccgt atcttgggaa
    11341 gtcaccctct gtttcaaagt caacagcaac gccgtcctcg tcacggataa ccttaacctt
    11401 agcgtactta atagcgctga gtgagtcaac aacatgtgag aagcctgcaa tacctgttgc
    11461 aaatgttctt cttacatctg tatcgataag agccatttct gctgcctcat agtagtactt
    11521 atcatgcatg tagtgaatca tgttaagtgt gcctacatag aggtgagcaa gccaatccat
    11581 cattgtgtca tacttcttga taacttcgtc ataatcaagg tactctgatg tgataggtgt
    11641 atattcagga ccaacctgca tctttgtctt ttcatcaata ccgccgttga tagcgtagag
    11701 aaggcactta gcaaggttag ctcttgcgcc gaagaactgg atttccttac ctgtctgtgt
    11761 tgcggatacg cagcagcaga ttgagtaatc atcgccccat acaggacgca ttacatcatc
    11821 gttctcgtac tgaattgagc ttgttgtaac tgaaatatga gcagcatact tcttgaagtt
    11881 ctcgggaagt cttgaagaat aaagaactgt gaggtttggc tcaggtgaag gtcccatatt
    11941 ctcaagtgtg tggaggaaac ggtagtcgtt ctttgtaacc atagaacggc cgtcaatgcc
    12001 aagacctgca acttcgagtg tagcccatac agggtcgccc gagaagagct ggttgtaaga
    12061 ctcaattctt gcaaacttaa ccatacggca cttcataaca aagtggtcaa cgagttcctg
    12121 agcctgtgat tctgtaagtg taccgttctc aaggtcacgc tcgatgtaga tgtcgaggaa
    12181 tgttgataca cgaccaacgc tcattgcagc gccgttctga gtcttgatag cagcaagata
    12241 gccgaagtag agccactgaa ctgcctctgc agcgttctta gcaggctgtg aaatatcaaa
    12301 gccgtaagaa agtgccattt ccttcatatc gttaagagca cgaatctgat cagcgatttc
    12361 ttcacgaagc tggaagtcgc ctcttctcat accctgacgg tttgtttctg caaagtcctc
    12421 tttcttgcct tcgataagac ggtcaatacc gtaaagagca actcttctgt agtcaccgac
    12481 gattctgcct ctgccgtatg tgtcgggaag acctgtaaga atcttgttgt gacgggcaag
    12541 cttcatctcg ggagtgtaga tatcgaacac accctggttg tgagtcttgt gatattttgt
    12601 aaagatttcg tggagtttag ggcttggagt gtagccatac atctggcatg actgctcagc
    12661 cattttgata ccgccgtaag gcataaatgc acgcttgaga ggcttgtctg tctgaagacc
    12721 tacaaccttt tcaaggtctt tatcaagata tgcagcgccg taagctgtga tgccgcttac
    12781 aacctcagtt tccatatcaa gaacgccgcc cttggctctt tcttccttct ggagttcctt
    12841 gagctcgccc cagagcttgt ctgtagcttc tgtaggacct tcaaggaaag actggtcgcc
    12901 gtcataaggt gtgtagtttc tctgaatgaa gtctctgaca tcaatgtcgg actcccattt
    12961 gccacctgca aaatttgtcc attcttctct cattactgta aaacctccga taatgataat
    13021 taatactgaa ttttgtatat gacacaaaaa aatgccgact caattccaag cagacgcccg
    13081 gtaaggtcag ctccttgaaa aaatcgtcat acatccttgt attctgtcat ttattcactt
    13141 ttataatcat ataaccaaca ccattaaaat aacacttttt aagggcgttg tcaagcattt
    13201 tgagatactt tttacaccac tttttcacac tcaaagcact atggtaaatg agtacaattt
    13261 tagggtatga ggaacattat tttcagcaga ttttttcccg tatttgtgcg gaatattttg
    13321 tcatatgcct gctctgctgc actgcggctt gaatcgtcct cgtaaaggtt cacaaggaag
    13381 tctgcctcta ccaaaattcg gtacggcaaa gtatcaatat ttccataggt gtgatggtgt
    13441 cccacaaggt aacaaacttt gtcaataaat gttttttcgt agccgagagc agcaagcaac
    13501 ttttcagcct cgtgaggacc ttcaagttcc tgatactttc ctgcagacga attgtacttt
    13561 tcttcgctca cctttatgcc gatgtcgtga acgattgcgg agatttcaag aagctcctga
    13621 tcgtcgggca aaagattttc actttcaccg attgtctttg cgaatgaata aaccttgaga
    13681 aaatggtgaa ttcttttctt gtcacttcca aaatattcaa tcatagcagt tataaccctg
    13741 tcggttttca tattatcact ccttacggcg agccgccgta ccctattcgt gtagaccgtt
    13801 ttttgtttgt gcaattctgt aggggtagca ttgcgactat atttcagacg ggcggattcg
    13861 cacaaacaat cactttttca tacttcttat atatgcaaat gtcttttctt caccctcatc
    13921 tctcagcata accaataatt tttcaagcaa ggcctcggtg ttggggtgca tacggtgttt
    13981 gcctctgatt ctgcagaaat atgtaaacgg agcgccgtcc gtgtaatttt tgccgttgta
    14041 gattttgctt gcggcaactc ggtcgcagaa catttcgata acatatttta caggcatttc
    14101 aacattttca atctgctttg tctttgggtt gtaatcgttc cagtattcgt aatggtgacg
    14161 gtttctgccc ttgtgatgca gccacgcctg tgaatagccg tacagctctc tttccttttc
    14221 attgggactt ctcgtgccct gaaaatactt tgcacccgga ataaattctg taggcgaata
    14281 ctttgacaaa tcgtgtatta atccctgtct gagaattcct gcccttgcac agttggcaat
    14341 taccttgtgc ctgtgacggg ttattgttct gaaatgttta atcggatgtg ccataattat
    14401 caccataaat tgttagtttg gaaaatacaa aacattctcc gactgacatt ttaccacatt
    14461 tctcaccgat ttaaaatagc acttgcaaga ttgtcgaaaa aaagttataa tatacaaagg
    14521 ttaaaatttt gtaaccattt aatgttaaat tctataagga taggtaatct atgaaaaaga
    14581 aaattttcat tcttttactt tgtgttgtcc tcattgcaac ctgcatatta tgcggtgtga
    14641 cgggaatttt cggaaatgat tctcaaaatt ctccaaaacc gcagacgcac gatacggcag
    14701 taaccgaaaa tatgacattt ccgagcaagg tcgattcgct cacattaaaa gtaggcgaat
    14761 caaagcttat tgaactgtca tccgaaaaag caaaatccgt taccaaatgg acaagctcgg
    14821 acagtaaaat tgttaccgtt gatgacggcg gaagggttga cgctctcaaa gagggtacgg
    14881 ctctgatttc tgccatttca aaagacaaat caaagtcgga atttcaggtt acggtggcaa
    14941 aatcaaccac gaaaaaacag caaagctact caacctgtat aacggcaaat cttgacaagc
    15001 ttgaaaacaa taagcgtaac acggcaaaaa acctgtacgc aatcaaggtc aaccgcacgg
    15061 caaactgcgt gacggtttac acatatgacg aaaagggcaa gtacacaatc cccgtaaggg
    15121 cgatgatttg ctccacaggt cttgacaatt cgacaatcac gggtgactac acaatcggaa
    15181 tcaagtccga atggctttcc cttgtgggcg atgttttcgg aagatacatc agcggaattt
    15241 ctggcgatta tcttttccac tccgttccct actactcaat gagcgaagaa gatttggagc
    15301 ttgaggagtt caacaagctt ggcgaacagg cgtcacaagg atgcgtaaga cttgcggttt
    15361 cggatgcaaa gtgggtttat gacaactgcc ccacaggcac aaatgtaagc atatatgacg
    15421 acgcagaaaa tgcaggccct ctcggaaaac cggatgcaat caaaatcacc gattttacca
    15481 acaaatggga tccgacagac agcaataaaa aatgcccgta tgccaaagca acaccaataa
    15541 tcagcggtgc aaacgattac acaatcaaaa gcggcggcga attttacgcc cttgcaggag
    15601 taacagccgt tgacacctgc ggcaacgaca taacatcgaa tatcgaagtt ttcggcaatg
    15661 tagtaaccac ccgaaaaggc aagtacaagg taacatattc agtcaccgat gtgcttaaaa
    15721 gaacatcaag cgtaacgatt acggtaacgg tgcaataaac atggtgcgcc actgttctcc
    15781 gagcggagct tttaaattga aagtggaaaa ttgaaaatgt aaaataaaaa tgcggttggc
    15841 aatgtgccac cgcatttttt atgttcgtgt gttcgtgcag acggttttaa tagtaaatta
    15901 caaatgttgc ccgagcataa catagcaatt gtttgtacat acagtagcgg cggtcagtga
    15961 ccgccatttg atttggttgc aaagccaaat caaccacaca gcaacataca tattttgacc
    16021 aagtataaca ttccaattat ttttgcaatg tatgttttag ggggaaccgt gttcgcccgt
    16081 tcgtatgcaa cgcatacgat tgcacgcaat gcgtgcaagg ttcaatacac aattataatc
    16141 acatcaaaac atatatgatt aaacaaaata tttcatcaag gcgggcggcc gatgtgtgca
    16201 gtgtagtaac atagtataca acagtgcaaa gacatagtat acagttttat gataaaataa
    16261 atggcaagaa aatagcaaat gaaggagctg tttttatgcc gtgggagtgt aaaactgtgg
    16321 aaaaacaaag at
//
