LOCUS       c00036_gnlPro..        15097 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NJKIFNDI_36.
ACCESSION   c00036_gnlPro..
VERSION     c00036_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 00:28:17
            Original ID  :: gnl|Prokka|NJKIFNDI_36
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15097
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..66
                     /locus_tag="ctg36_1"
                     /transl_table=11
                     /translation="VDKNVEKIILILSIIEHFGGD"
     protocluster    1..15097
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[85:5097]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      86..5097
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15097
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15097
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             86..1402
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_2"
                     /sec_met_domain="SLBB (E-value: 1.4e-17, bitscore: 54.0,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 7.1e-49, bitscore:
                     156.2, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 7.1e-42, bitscore: 132.2,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.5e-05, bitscore: 14.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGILTFKGGVHPYDGKELSKNSPVVKYLPKGDMVYPLSQHIGAPA
                     AAIVQKGDHVLAGQKIADAAGFVSSPIHSSVSGTVKGIEPRLTATGSMVSSIIIENDQQ
                     YESVEFTPARLEDLSKEEILARIKEGGVVGMGGAGFPTQVKLAPKEPEKIDHILVNGAE
                     CEPYLTSDYRRMLDDSEKLIEGLRVMLKLFDNAKGYICIEDNKPDCIAKLKEMVKDIPR
                     IEVAELMTKYPQGGERFLIKAVTDREINSAMLPADAGCVVDNVDTVIAVYEAVILGKPV
                     MDRIVTVTGQGIKNPQNFDVLSGTDMAELIEAAGGLTDNVSKVISGGPMMGFAMYDTHV
                     PCIKTSSACLCLEKDDVADAEQTACINCGRCVGVCPGHVIPARLATFAEHGDMKSFQKF
                     DGMECCECGCCSYICPAKRPLTQMIKSMRKMVLASRKKK"
     CDS             1418..2395
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_3"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 8e-121, bitscore:
                     393.4, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQMLHVSSNPHVRDKMTTSKIMQLVALALLPTTLFGIYNFGLRA
                     LLVVVITVASSVFFEWIYDKLMHKKNTITDFSAVVTGLLLALNMPASIPLWMPVLGSAF
                     AIIVVKQLFGGLGQNFMNPALAGRCFLMISFAGKMTDFAVSDSFRGVVDTVSGATPLAA
                     LKQNGFTDSSVSVLHMFIGDIQGTIGETSALAILIGAAILLVFKVIDLKIPLTYIGSFA
                     VFVILYMLGTGKGFDVNYLFSHIFGGGLMLGAWFMATDYVTTPITPRGQYVYGVCLGVL
                     TAVFRLFGGSAEGVSYAIIFCNLLVPMIERVTRHPAFGKGGKKA"
     CDS             2392..3000
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_4"
                     /sec_met_domain="FMN_bind (E-value: 1.7e-20, bitscore:
                     64.1, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNRIIKDTIAITVITLVAGLALGVVQDITADPIAKQEAQAKQDA
                     YKAVFADADSFETVDVDADAMQSYLDENGYAAQSIDETMLAKDASGNELGYAFTVTTSE
                     GYGGDIQFAMGIQDDGTLNGISILSIGETAGLGMRANTDAFKDQFKDKNVDKFEYTKTG
                     ATADDQIDALSGATITTNAMTNGVNAGLCAFQYEKGGNQ"
     CDS             3000..3710
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_5"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.9e-72, bitscore:
                     232.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPNTPAERLYNGIIKENPTFVLMLGMCPTLAITTSATNGIGMGL
                     TTTVILAASNLMISLLRNFIPDRVRMPAFIVVVASFVTVVQLLLQGFIPSLYDSLGIYI
                     PLIVVNCIILGRAEAYASKNKPIASLFDGIGMGLGFTLSITCIGAVRELIGAGSLFGHQ
                     ILPLADAAAGKAGYEPITIFILAPGAFFVLAALSALQNKFKIGAAKRGIDPSNPDCGGS
                     CAACGNTMCKGKRG"
     CDS             3717..4292
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 6.5e-63, bitscore:
                     202.5, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKELLIILVSSAIVNNVVLSQFLGLCPFLGVSKSVETAAGMGGAI
                     IFVITLSSFVTGIIYNAILVPTNLTYLQTIVFILLIAALVQFVEMFLKKTMPSLYQALG
                     VYLPLITTNCAVLGVALTNVQKEYNVLQGTVNGFATAVGFTISIVLMAGIREKIAYNDI
                     PKSFQGFPTVLLTAGLMAIAFFGFSGLI"
     CDS             4306..5097
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1020:4Fe-4S binding domain (Score: 31.8; E-value:
                     2.7e-10)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_7"
                     /sec_met_domain="Fer4_7 (E-value: 1.5e-10, bitscore: 32.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 7.2e-08, bitscore: 22.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 2.3e-16, bitscore: 49.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.8e-05, bitscore: 15.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIGAIIAATVLVAAVGLFIGVFLGVAGKKFAVEVDEKEVAVREA
                     LPGNNCGGCGYPGCDGLAAAIAKGEAPVNGCPVGGEPVGKVIAAIMGQEVVETARQVAY
                     VKCAGTCEKTKDNYEYTGVEDCEMMAFIPGGGAKSCTYGCLGFGSCVKACPFGAIDVVN
                     GVAVVDKEACKACGKCVAKCPKHLIELVPYEQTTFVQCSSHAKGKAVTSACEVGCIGCK
                     KCEKTCPNGAITVDNFCAHIDYSKCTNCGACKEVCPRHIIQ"
     CDS             5232..5840
                     /locus_tag="ctg36_8"
                     /transl_table=11
                     /translation="MIAFVHGMAVDMTESSVVVEAGGIGYEIYMTGADLSEIRMGEDVK
                     VHTYFSVREDAMKLYGFRDKDDLQMFKLLLGVNGVGPKAALGVLAGITADELRFAILSD
                     DVKTLSKAPGIGKKTAQKLILELKDKMKLEDAFELKLAHEQERAAVGAGEVSDGRQEAV
                     EALVALGYSSADALRAVRKVTDVPPDDVEGLLKAALKNF"
     CDS             5920..6924
                     /locus_tag="ctg36_9"
                     /transl_table=11
                     /translation="MEKRIITTDVTEEDFSLEGNLRPQTLDDYIGQEKTKSTLKVYIEA
                     AKQRHDALDHVLFYGPPGLGKTTLSGIIANEMGVHMKVTSGPAIEKPGEMAAILNNLQE
                     GDILFVDEIHRLNRQVEEVLYPAMEDYAIDIMIGKGASARSIRLDLPKFTLVGATTRAG
                     LLSAPLRDRFGVMHHLEFYTHEELKTIIIRSAQVLGVEIDEKGAAEIAKRSRGTPRLAN
                     RLLKRVRDFAQVKYDGRITYDVACFALNLLEVDQYGLDKIDRRILQTMIVNFQGGPVGL
                     ETLAAAIGEDSGTLEDVYEPYLLQNGFLNRTPRGRMASALAYEHLGYQMPEKN"
     CDS             7059..7466
                     /locus_tag="ctg36_10"
                     /transl_table=11
                     /translation="MAVKNTAKVIIGGKIITLGGYESEEYFQKVASYINKKMDELSAMP
                     GYSRQPMETKHTLISLNITDDYFKAKKQAEVFEQDLQQKDQEMYDLKHELISLRMQIEE
                     AQKHEQEALEQKSLLEGKNKELEKQIDELLK"
     CDS             7595..9790
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_11"
                     /sec_met_domain="Peptidase_U32 (E-value: 2.4e-82, bitscore:
                     266.2, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRREEIELLAPAGSYEGFEAAIGAGADAVYVGGAAFGARAYAKNF
                     GEEELLRAIDTAHIHGRKLYLTVNTLLKNRELSEQLYDYLLPYYKEGLDAVIVQDMGVF
                     KMIREMFPGMHLHASTQMTVTGPEGMKFLEEQGASRVVTARELSLEEIRRMHETSPIEI
                     ESFIHGALCYSYSGQCLMSSILGGRSGNRGRCAQPCRLPYQTALCCGENGRRSEKRKAQ
                     ELCPLSLKDISTIEILPQILEAGVTSLKIEGRMKQPGYTAGVTSVYRKYLDLLFEKGAE
                     NYRVAEEDKRYLLDLFNRGGSCTGYYQMQNGPSMMAFSNEKKTGDVSPVLRKKKEKIQG
                     TFILFPGSPAILDVSCRGIHGFASVGEVQYAQNQPLTEERIRSQMEKLGNTEYEWENLE
                     IQMDENIFIPMKMLNEARREALESLENELLKPYKREENNGKKRLSEDAGRKADSPKQKN
                     LPIYISCEEKSTALALYKREGIHGMYLNADAMEVCLDDCVSRGMEMYLSLPHIMRGEMP
                     RELLTRIREWMDRGMTGFLVRNLETFAVLRKAGLAEKCVLDHSMYTWNDEAADFWKDQK
                     VLRNTVPLELNEGEIRHRDNRDSEMLIYGYLPLMISAQCVHKNLYGCNHKEEGVTLKDR
                     YDKEFTAKCICNPWKTENTDFCIPCYNIIYNSIPYGLLKEKSQIDRLGVSSLRLAFTIE
                     KPQDAVKIYEEFRDVYRDGKNPPKREYTKGHFKRGAE"
     CDS             10165..11169
                     /locus_tag="ctg36_12"
                     /transl_table=11
                     /translation="VIVAGVNVVALIVPVLIRKMKFLKDLTWVYAGIGIVLLAAVFVLA
                     KTSYGAKLSLMGIQPSEAIKITFVFFMAALLRKGADFSKVVQATVVAGLHVGILVISRD
                     LGSAVIFFAAYLVMIYVASRNVGYLALGLAGGSAGAVVAYHLFGHVRQRVTAWKDPMAV
                     YQNEGYQIVQSLFAIGTGGWFGMGLCQGSPEKIPVVKNDFIFSAICEELGGIFAICLIL
                     VCMSFFLMIVNIALKIKKPFYKLIALGLGTEYAFQVFLTIGGATKFIPMTGVTLPLVSY
                     GGSSVACTVLMLAIIQGLYILREDEDEEIERYRRKGTAQRVEEAPEAQSPGDF"
     CDS             11129..12580
                     /locus_tag="ctg36_13"
                     /transl_table=11
                     /translation="LKKRQKRKAREISEKRRPRNREYTLVSCFFVLIFVSMIGYLIYFN
                     YAKSDDFINSPYNTRQDTFSDRVVRGKIISADGQVLAQTNVYEDGTEERTYPYANMFAH
                     VVGYDTNGKSGLESEANFQLLTSHEFFLNQMKNEFKNQKNTGDSVITTLNADLQSTAYN
                     ALGDRRGAVVAIEPSTGKILVEMSRPDFDPNTISQNWDTLVNDSNDSSLLNRATNGAYP
                     PGSTFKVVTALDYFRTKGSLEGFSYLCEGSITREDHTIRCYGGTVHGQEDFYSAFANSC
                     NSAFAEIGTMLGGSSLKKTAENLLFNKSLPLSSYKKSTFTLNGKSSVAEVMQTAIGQGN
                     TLVSPMHMALITSAIANGGELMKPYLIDSVVSSDGETVKTTEPESYKRLMTTNEANILG
                     KLMKGVVENGTASALNGRGYTVAGKTGSAEFDENGSSHSWFIGYSNVDDPDLVVAIIVE
                     NGGTGSEAAVPIAEQIFDAYYYDKQ"
     CDS             12757..13212
                     /locus_tag="ctg36_14"
                     /transl_table=11
                     /translation="MIEATSCGGVVIHRGKILTLYKSYRNRYEGWVLPKGTVEPGETHE
                     QTALREVMEEAGVRATIVKYIGKSQYNFTVPEDVVFKEVHWYLMTADNYHSKPQREEFF
                     VDSGYYKFHEIYHLLRFSNEKQIVERAYQEYLEMRSNGLWGKQHKYY"
     CDS             13317..13628
                     /locus_tag="ctg36_15"
                     /transl_table=11
                     /translation="MLKWQENFLAGESVKDPEKIKKKLNSGKPVLGIYLLTLSENPVNL
                     MDIIPAAMLIQKSFYGICPKIIGMAKGKEEALEMVRSLIDEMYRETGTFATAEYIENR"
     CDS             13633..14661
                     /locus_tag="ctg36_16"
                     /transl_table=11
                     /translation="MLHILWLILKFILIILGILLGLLLLAVLLVLFCPVRYKASAVKAE
                     GGWKQTEGEGIVSWLFHGISLRAEWKDQQMEISFHLFGIPVDKLLKKRQEKRAITKKSG
                     KNPEKSGAEKVSVSGIDGNREEEHKKSVVDHPKSENMETEDLKTDRNSASGTSADTERI
                     RNSQISGQQELNADDTDRNSLKKRQFFIKGIYDRIRNIFQSIRTKLQNIRRTFGKIKKN
                     VSWWKAFIEHPRVTAARKLVWKHGKFLLKHIFPTRIEGQVTFSFEDPALTGAALAVLGM
                     TIPFHKNCIQIDPRFDSENYLYGNIRAKGRIYGFVPVRAAVSIYFNKNIKYVIKRWKTR
                     RA"
     CDS             14664..15035
                     /locus_tag="ctg36_17"
                     /transl_table=11
                     /translation="MANENNFKETVNSLFKGMDSFISAKTVVGEAIHVGDTIILPLMDV
                     SFGVGAGAFSGEKKDNGGGGMAGKMTPCAVLVIQNGTTKLVNVKNQDGLTKILDMVPDF
                     VDRFTSGKGDEESVGESEK"
ORIGIN
        1 gttgataaaa atgtagaaaa aattatattg attttatcaa taattgagca ctttggtggt
       61 gattaattta aaaggcggga actaaatggg tattttaacc tttaagggtg gtgttcatcc
      121 ttatgacgga aaagaattat ccaagaacag tccggtagtg aaatatctgc caaagggaga
      181 tatggtatat cctctttccc agcatatcgg tgctccggct gcagcgatag ttcagaaggg
      241 agaccatgtg ctcgcaggac agaagatcgc agatgctgcg gggtttgtct catcaccgat
      301 ccattcgtct gtttccggta cggtaaaagg aatcgaaccg cgcctgacag caacaggttc
      361 tatggtcagt tccattatca ttgagaatga ccagcagtat gaaagtgtgg aatttactcc
      421 tgcacgtctg gaagatcttt cgaaagagga gattttggcg agaattaaag aaggcggagt
      481 tgtgggaatg ggcggcgccg gattccccac acaggtaaag cttgcgccaa aggaaccgga
      541 gaagatcgat catatccttg taaacggtgc cgagtgtgaa ccctatctta ccagtgacta
      601 cagaagaatg ctggatgact ctgagaagct gatcgagggc ttaagagtta tgctgaagct
      661 ctttgacaat gcgaagggat atatctgtat tgaggataac aagcctgact gtattgcgaa
      721 actgaaagaa atggtaaaag atattccacg tattgaagta gcagagctga tgaccaagta
      781 cccacagggt ggtgagcgtt tcctgatcaa ggctgtcaca gacagagaga ttaactctgc
      841 catgcttccg gcagatgcag gatgcgtagt tgacaacgta gataccgtaa ttgctgttta
      901 tgaagccgtt atccttggaa aacctgttat ggaccgtatc gtgacagtaa caggacaggg
      961 gattaagaat ccgcagaact ttgatgtcct ttccggaaca gatatggcag agcttataga
     1021 agctgccggc ggactgacag acaatgtatc caaagtaatt tcaggtggtc ctatgatggg
     1081 atttgccatg tatgacactc atgtaccatg tattaagaca agctccgcat gtctctgcct
     1141 ggagaaggat gatgtggcag atgccgaaca gactgcatgc attaactgcg gcagatgtgt
     1201 aggagtctgt cccggccatg tcattcctgc aagacttgca acctttgcag agcatggtga
     1261 catgaagagc ttccagaaat ttgatggtat ggagtgctgc gaatgtggct gctgcagtta
     1321 tatctgccct gccaagcgtc cgctgaccca gatgatcaaa tctatgcgta agatggttct
     1381 ggcaagccgt aagaaaaagt aaaaggggga catcgtaatg gatcagatgt tacatgtatc
     1441 atccaatccc catgtccggg ataagatgac aacaagcaaa atcatgcagc ttgtggcact
     1501 ggcgcttctg ccgaccacac tgtttggaat ttataatttt ggccttcgtg ccttactggt
     1561 agtagtgatc accgtcgctt ccagtgtatt ctttgagtgg atttatgaca agctgatgca
     1621 taagaagaac acaattacag acttcagtgc agttgttaca ggtttattac ttgcattaaa
     1681 tatgcctgca tcaattccgc tctggatgcc tgtacttggc agtgcatttg cgatcatcgt
     1741 tgtaaaacag ctctttggtg gtctgggaca gaacttcatg aacccggcac ttgcaggaag
     1801 atgtttcctg atgatctctt tcgcaggaaa gatgacagac ttcgcagtaa gcgacagctt
     1861 cagaggtgtg gtagatactg tatccggtgc aactcctctg gcagctctga aacagaatgg
     1921 atttacagac agttctgtat ctgtattaca tatgtttatc ggtgatatcc agggaactat
     1981 cggtgagact tctgcccttg cgatcctgat cggagcagca atccttctgg ttttcaaggt
     2041 gatcgatctg aagattccgc ttacctatat tggaagtttc gcagtatttg taatccttta
     2101 catgcttgga acaggcaagg gatttgacgt gaactatctg ttcagccaca tcttcggcgg
     2161 tggtcttatg cttggtgcat ggtttatggc tacagactat gtcacaacac cgatcacacc
     2221 aagaggacag tatgtatacg gtgtctgcct tggtgtactg actgcggtct tccgtctctt
     2281 tggcggttcc gcagagggcg tatcttatgc gatcattttc tgcaacctgt tagttccgat
     2341 gattgaacgt gtgactcgtc acccggcatt tgggaaaggg ggcaaaaagg catgagtaac
     2401 agaattatca aagataccat agccattaca gtgatcacac tggtggcagg acttgccctt
     2461 ggtgtagtcc aggatattac agcagatcct attgcaaagc aggaagcaca ggcgaaacag
     2521 gatgcgtata aggcagtatt tgcagatgcg gacagctttg agacagtgga tgtggatgcg
     2581 gatgccatgc agtcttatct ggatgagaac ggatatgcgg cacagtccat agatgagact
     2641 atgcttgcca aagatgcttc aggcaatgaa ctgggatatg catttacagt aaccacttcc
     2701 gagggttacg gcggagatat ccagtttgca atgggtatcc aggatgacgg taccttaaat
     2761 ggaatttcca ttctttccat cggtgagacc gcaggtcttg gtatgagagc aaacacagat
     2821 gcatttaagg atcagttcaa agataagaac gtagacaaat ttgaatatac aaagaccggt
     2881 gccacagcgg atgatcagat cgatgcgtta agtggtgcca ctattacaac gaatgccatg
     2941 acaaacggtg tcaatgccgg attatgtgca ttccagtatg agaaaggggg aaatcagtga
     3001 tgaaaccaaa cacacctgct gaacgtttat ataacggaat catcaaagaa aatcctacct
     3061 ttgtactgat gcttggtatg tgtcctacac tggctatcac cacatctgca accaatggta
     3121 tcggaatggg acttactaca acagtgatcc ttgcagcatc caacttaatg atctctcttc
     3181 tgagaaactt tattccggac agagtgcgta tgcctgcatt tatcgtagtt gttgcttcct
     3241 ttgtaacagt tgtacagctt cttttacagg gatttattcc aagcctgtat gactcccttg
     3301 gaatctatat tcctctgatc gtagttaact gtatcatcct tggacgtgca gaagcatatg
     3361 catccaagaa taaaccgatt gcctctctgt ttgatggtat tggtatgggt cttggattta
     3421 ccttaagtat cacctgtatc ggtgcagtac gtgagctgat cggcgcaggt tctctgttcg
     3481 gacatcagat ccttcctctg gcagatgctg cagcaggtaa ggctggttat gaaccgatca
     3541 caatctttat cctggcaccc ggagcattct ttgttctggc agcgctttct gcattacaga
     3601 acaaattcaa aatcggtgca gccaaacgtg gcattgatcc aagtaatcct gattgcggcg
     3661 gaagctgtgc agcctgtggc aataccatgt gtaagggaaa aagggggtaa tggattatga
     3721 aagaactttt gatcatactt gtaagctcag cgattgtaaa taacgtagtc ctcagccagt
     3781 tccttggtct ctgtcctttc cttggtgttt ccaagagtgt tgagacagca gccggcatgg
     3841 gcggtgcgat catcttcgtt attacactgt catcttttgt gacaggtatt atttataatg
     3901 ctatcctggt tcctacgaac ctgacttatc tgcagactat cgtattcatc ctgctgatcg
     3961 cggcgctggt acagtttgta gagatgttcc ttaagaagac aatgccttcc ctgtatcagg
     4021 cacttggtgt gtatcttcca ctgatcacaa caaactgtgc agttcttggt gttgccctta
     4081 caaatgtgca gaaagagtat aatgttcttc agggaacagt gaacggattt gcaacagcag
     4141 tgggctttac tatttccatc gtgctgatgg ctggtatccg tgagaaaatc gcatacaatg
     4201 acattccaaa atccttccag ggattcccta cagttctgct gacagccgga ctgatggcaa
     4261 ttgccttctt cggattttca ggactgattt aaggagggga ctggtatgaa tataggagca
     4321 attatcgcgg caactgtact ggttgcggca gtaggtcttt ttatcggtgt tttccttggt
     4381 gttgccggta agaagtttgc tgtggaagtg gatgagaagg aagttgctgt tcgtgaggcg
     4441 cttcccggta ataactgcgg tggctgtggt tatcccggct gtgatggtct ggcagcagcg
     4501 atcgccaaag gtgaggcacc tgtaaatgga tgtccggtag gcggtgagcc tgtcgggaaa
     4561 gtgatcgcag cgatcatggg acaggaagtt gtggagactg cccgtcaggt ggcgtatgtg
     4621 aagtgtgcgg gtacctgtga gaagacgaag gataattatg agtatacagg tgtggaagac
     4681 tgtgagatga tggctttcat tcccggtggt ggtgcgaagt cctgtactta tggatgcctt
     4741 ggttttggaa gctgcgtgaa ggcctgtccg tttggggcga ttgatgttgt gaacggtgtg
     4801 gcggttgttg ataaggaggc ttgtaaggcc tgcggtaagt gtgttgccaa gtgtccgaag
     4861 catctgatcg agcttgtgcc ctatgagcag actacgtttg tgcagtgtag ttctcatgcg
     4921 aaaggtaagg ctgttacttc tgcgtgtgag gttggctgta tcggatgtaa gaagtgtgag
     4981 aagacttgcc cgaatggggc gattacggtt gataatttct gtgcgcatat tgattatagt
     5041 aagtgtacga attgtggggc ttgtaaagag gtttgtccga gacatattat tcagtaatgg
     5101 gaggaagaac tgctgtgtga aggcatggcg gttctttttt tcgattaagg gatgcgaata
     5161 tatgtttgcg ttatggggtg ggatgtggta tgatgaatcg gaagtgatga atttgggacg
     5221 gaggatgtat catgattgcg tttgttcatg gaatggctgt ggatatgact gagagctcgg
     5281 tggttgttga ggccgggggg attggttatg agatatatat gacgggggca gatttgtctg
     5341 agattcgtat gggggaggat gtgaaggtcc atacttattt tagtgtgaga gaggatgcca
     5401 tgaagctgta tgggttcagg gataaggatg atctgcagat gtttaagctg cttcttggcg
     5461 tgaatggtgt ggggccgaag gctgcgctgg gagttctggc ggggattaca gcggatgaat
     5521 tgaggtttgc aattctttcg gatgatgtga agacgttgtc gaaggctccg ggtatcggga
     5581 agaagacggc tcagaagctg attcttgagc tgaaggataa gatgaagctg gaggatgcgt
     5641 ttgaattgaa gctggctcat gagcaggaga gggcagcagt gggagccggt gaggtttcgg
     5701 atggcaggca ggaggctgtt gaggctctgg ttgcgctggg atacagcagt gcggatgcgc
     5761 ttcgggcggt gcgtaaggtt acggatgtgc cgccggatga tgtggaaggt cttttgaagg
     5821 ctgcgctgaa gaatttttaa ctgaagcagg atttcacgct ctggtagatt ggattgcctg
     5881 tattgttata gaattgttat aggttaggat gggtaacaga tggagaaacg tattataact
     5941 acggatgtga cggaggagga tttttctctg gaggggaatc tccggccgca gacgttggat
     6001 gattatattg gtcaggagaa gaccaagagt actttgaagg tttatataga ggctgcgaag
     6061 cagaggcatg atgcattgga tcatgttttg ttttatggtc ctccggggct tggcaagact
     6121 actctttcgg ggattattgc caatgagatg ggggttcata tgaaggtgac ttccgggccg
     6181 gctattgaga agccggggga gatggctgcg atccttaata atctgcagga gggagatatt
     6241 ctgtttgtgg atgagatcca ccgcttgaac aggcaggtgg aggaggtcct ttatcctgct
     6301 atggaggatt atgctattga tattatgatc gggaagggag cttctgccag gtctatacgt
     6361 ctggatctgc cgaagtttac actggtgggg gcgactacca gggcaggact tctgtctgca
     6421 cctcttcgtg accgttttgg tgtgatgcat catctggagt tttatactca tgaggagctt
     6481 aagacgatca ttatccgttc tgctcaggtt cttggagtgg agattgatga gaagggtgcg
     6541 gctgagattg ccaagagatc caggggaact ccgaggcttg ccaaccgtct gctgaagagg
     6601 gttcgtgatt ttgcgcaggt gaagtatgat ggacggatta cttatgatgt ggcgtgtttt
     6661 gcgctgaatc ttctggaagt ggatcagtat ggtctggata agattgacag aaggattctt
     6721 cagactatga tcgtgaattt tcagggtggt cctgtgggac tggagacttt ggctgcggcg
     6781 ataggggagg attccggtac gctggaggat gtgtatgagc cttatctgct gcagaatgga
     6841 ttcctgaacc gtacgccgag aggacgtatg gcatcggcgc ttgcgtatga gcatctgggc
     6901 tatcagatgc cggagaaaaa ctgaagttaa gggcgtaaaa atataaaaaa gtaaaagttt
     6961 tttaaaaatt cctatacatt tcgactgctt tcgagtataa tgaagtaaat gtccggggtt
     7021 ccgggcagat tgaaggaaga tacaggaggc tcgtacggat ggcggtcaaa aatacagcaa
     7081 aggtaatcat aggtggtaag attattacgc tgggaggcta tgaatcggaa gaatattttc
     7141 agaaagtagc atcctatata aataaaaaga tggatgagtt aagtgctatg ccgggttaca
     7201 gcagacagcc catggagacc aagcatacac ttatcagcct gaatattaca gatgactatt
     7261 ttaaggcaaa gaaacaggcg gaggtttttg aacaggattt acagcagaag gatcaggaga
     7321 tgtatgatct gaagcatgag ctgatctcgc ttcgtatgca gattgaggaa gcgcagaagc
     7381 atgaacagga agccctggaa cagaagagcc ttctggaggg aaagaataag gaactggaaa
     7441 agcagattga tgagctgctg aaataacaga ggggggatta cttcggtgat ttccccttta
     7501 tgatttgttt catatgtatt cgatttgaat attatagcaa tgctcataaa taatgcattt
     7561 aagatgactg ttatagaaaa cgtgaggtat agaattgaga agagaagaga ttgaacttct
     7621 ggcacctgcc ggttcctatg agggatttga ggcagcgatc ggtgcaggtg cagatgcggt
     7681 ttatgtaggg ggagcagcct ttggcgcgcg ggcctatgcg aagaatttcg gagaggaaga
     7741 gcttttgcgt gccattgata ctgctcatat ccatggcagg aaactttatc tgacagtgaa
     7801 tacgctgttg aagaacaggg aactgtctga acagttgtat gattatctgc ttccatatta
     7861 taaggaaggt ctggatgcgg tgatcgttca ggatatgggt gtgtttaaga tgatcaggga
     7921 gatgtttccg ggtatgcatc ttcatgccag cacgcagatg actgtgacag gtccggaggg
     7981 gatgaagttt ctggaagaac agggtgcttc cagagtggta actgccagag agctttccct
     8041 tgaggaaatc cggaggatgc atgagacaag tcctatcgag attgaatctt ttatccatgg
     8101 agctttatgt tacagttatt cgggacagtg cctgatgagc agtatcctgg gtggaagaag
     8161 cggtaacaga ggaaggtgtg cacagccttg ccgtctgcct taccagacgg cgctttgttg
     8221 cggggaaaat ggcagacggt cagagaaaag gaaagcgcaa gaactatgtc ctctgagtct
     8281 gaaggatatt tctacgatag agattcttcc gcagattctg gaggctggtg ttacttctct
     8341 taagatagag ggcaggatga agcagccggg atatacagca ggggtaactt ctgtatatcg
     8401 gaagtacctg gatcttcttt ttgagaaggg agctgagaat tacagggtag cagaggagga
     8461 taagagatat ctgctggatc tgtttaacag gggaggttcc tgtaccggtt attatcagat
     8521 gcagaatggt ccgtccatga tggcattcag caatgagaag aaaacaggag atgtcagtcc
     8581 tgtattaaga aaaaagaaag aaaaaattca gggaacattc attctttttc cgggaagtcc
     8641 tgctatactg gatgtgtcat gcaggggaat ccatggattt gcgtctgtgg gtgaggtaca
     8701 gtatgcgcag aaccagccgc tgacagagga gcgcatccgt tcacagatgg agaagcttgg
     8761 aaatacagaa tatgagtggg aaaatctgga aatccagatg gatgagaata tttttatccc
     8821 gatgaaaatg ctgaatgagg cgagaagaga ggcactggaa tctctggaaa atgaattgct
     8881 caaaccatat aagagagaag aaaataatgg gaagaaacgc ttatcagagg atgccggaag
     8941 aaaagcagat tcgccaaagc agaaaaatct tccgatttat atttcctgtg aagaaaaatc
     9001 cactgcactg gcgttatata aaagagaggg gatacatgga atgtatctga acgctgatgc
     9061 catggaggtc tgcctggatg actgtgtaag cagaggaatg gagatgtatc tgtctcttcc
     9121 gcatattatg agaggtgaga tgccccggga gcttctcacc aggatcagag agtggatgga
     9181 cagaggaatg acaggatttc tggtaagaaa tctggagact tttgcagttc tgcgaaaggc
     9241 aggtctggct gagaaatgtg ttctggatca cagtatgtat acatggaatg atgaagctgc
     9301 tgatttctgg aaagatcaga aagtcctcag aaatacggta ccgcttgagc tgaacgaagg
     9361 ggaaatccga cacagagata accgggacag cgagatgctg atctacggat atctgcctct
     9421 tatgatatcg gcccagtgtg tgcataaaaa tctttacgga tgtaatcata aggaagaagg
     9481 ggtaacttta aaagaccgtt acgataaaga atttacggcg aaatgtatat gtaacccatg
     9541 gaaaactgag aatacagatt tctgtatacc ctgctataat atcatttaca acagtatccc
     9601 ttacggcctg ttgaaagaga aatcacagat agacagactt ggtgtctctt ccctgagact
     9661 tgcatttacc attgagaagc ctcaggatgc ggtgaagata tatgaagagt tcagagatgt
     9721 ttatcgtgat gggaagaatc ctccgaaacg ggaatataca aagggacatt ttaaaagagg
     9781 agccgagtaa ggcatatgat taatgtaatt gtagaattat ccaagtatgt gatccttacc
     9841 ctgatggtga tttatacctt tcactgtttc tatctggtga aacagcagag tgaggaggag
     9901 agaaacgaat cgctgcgcca gcagctgatg cttatctttt ttatggattt cactgcgttt
     9961 ctggtcatct acctgaagac aggtaagttg caggtcgtgt tgttttatgt cgaaatgatg
    10021 gcattttttg cgggaatcca gattttgtac aggatttttt ataagaaagc atcgatttta
    10081 ctgctcaaca atatgtgcat gcttctcagc gtaggattta ttatgctgtg caggctggat
    10141 gtttccacag ctaccagaca gctggtgatc gtggcaggcg taaatgtggt ggcattgatc
    10201 gtacctgtcc tgatcaggaa gatgaaattt ctcaaggacc tgacatgggt ttatgcggga
    10261 atcggaatcg ttttgctggc ggcggtattt gtgcttgcaa agacaagcta tggagcaaaa
    10321 ctttccctga tgggaatcca gccttcagag gcgataaaga ttacatttgt gttctttatg
    10381 gcggcattgc tgagaaaagg tgctgatttt tcaaaagtgg tccaggctac ggtagtggcg
    10441 ggactgcatg tggggattct tgtaatttcc agagaccttg gaagtgcagt gatcttcttt
    10501 gcggcatatc ttgtgatgat ttatgtggca tccagaaatg tgggatatct ggcacttggt
    10561 cttgcaggcg gatctgcagg ggcagttgtc gcatatcatc tgtttggcca tgtgcgtcag
    10621 agagtgacag cctggaagga tcccatggcg gtatatcaga atgaaggata ccagatcgtt
    10681 cagtcactgt ttgccattgg aaccggcgga tggtttggaa tgggattgtg tcagggttcg
    10741 cctgagaaga ttcctgttgt caagaatgac tttatattca gtgcaatctg tgaggaactg
    10801 ggtgggattt ttgcaatctg cctgatcctg gtatgtatga gtttcttttt gatgatcgta
    10861 aatattgcgc ttaagattaa gaaaccattc tacaaactga tcgcacttgg acttggtacg
    10921 gaatatgcat ttcaggtatt tctgacaatt ggcggagcaa cgaaatttat ccctatgaca
    10981 ggtgtaactc ttcctctggt cagctatgga ggaagttctg tcgcgtgtac agtactgatg
    11041 ctggcgatca ttcagggatt gtatattttg agagaagatg aggacgaaga aattgagaga
    11101 tatcgaagaa aaggaacggc gcagagagtt gaagaagcgc cagaagcgca aagcccggga
    11161 gatttctgaa aagagaaggc cccgtaacag agagtataca ctggtatcct gcttttttgt
    11221 gctgatcttt gtcagtatga tcggatatct gatctacttt aattatgcaa agagcgatga
    11281 ttttatcaat agtccctata atacaaggca ggatactttt tcagacaggg ttgtaagagg
    11341 taagatcata tctgcagatg ggcaggtgct tgcccagacc aatgtttacg aagacggaac
    11401 agaggaacgt acttatccct atgcaaatat gttcgctcat gtagtcggat atgacactaa
    11461 tggaaaaagc ggactggaat cagaggcgaa cttccagctt ctgacttctc atgaattttt
    11521 cctgaaccag atgaaaaatg agtttaagaa tcagaaaaat acgggtgatt ctgtgatcac
    11581 gacgttaaac gcagatcttc agtcaactgc ctataatgca cttggtgaca ggagaggggc
    11641 ggttgttgcc atagaaccct ctacaggtaa gattctggtg gaaatgagca gaccggactt
    11701 tgacccgaat actatttccc agaactggga cacactggta aatgattcca atgacagcag
    11761 tctgttgaac agagctacaa acggagccta tcctccggga tctacattta aggtggtaac
    11821 tgccctggac tatttcagaa ccaagggcag tctggaggga ttttcctatc tctgtgaggg
    11881 aagtattacc agagaagatc acacgatcag gtgctatggc ggaactgttc atggacagga
    11941 agatttttac agtgcttttg ccaattcctg taacagtgca tttgcagaga tcggaaccat
    12001 gctcggaggc agttctctga aaaaaacagc cgagaatctt ctttttaata agagtcttcc
    12061 gctttcttcc tataaaaaga gtacttttac attaaatgga aaatcttctg ttgcagaggt
    12121 tatgcagact gccatcggac agggtaatac gttggtatca cctatgcata tggcgctgat
    12181 taccagtgcg atcgccaatg gcggggagct catgaagcct tatctcattg attctgttgt
    12241 aagttcagac ggagagacag tgaagacaac agagccggag agctataaac gtctgatgac
    12301 aacaaatgag gcgaatatcc ttggaaagct tatgaaaggt gttgtggaaa acggaaccgc
    12361 atcggctctg aacggaagag gatatacagt ggcaggcaag accggatcag cggaatttga
    12421 tgagaatggt tccagtcatt cctggtttat cggttattcc aacgtggatg atccggatct
    12481 ggtagttgcg atcattgttg agaatggcgg taccggaagt gaagcagcag tgcccatcgc
    12541 agagcagata tttgatgcgt attattatga taagcaataa taaattccat gttgcaggca
    12601 atctggaatg aattttggct acgttactga gaacggagtg aacagtaatt aatcggtaat
    12661 atgttatgaa atgatattta tagcttgcgg gtttggaaaa aaagagatat actatactca
    12721 gtttataata ccacgcaaaa caggagggat tgcattatga tagaagcaac gagctgtggc
    12781 ggtgtggtaa ttcatcgggg taagattctt actttgtata aatcttacag gaaccgttat
    12841 gagggctggg tattgccgaa aggaacagtg gaaccaggcg aaacgcatga acagacagca
    12901 ttgcgggaag tgatggaaga ggctggagtg cgtgcgacca ttgtgaaata catcggaaag
    12961 agccaatata actttaccgt tccggaggac gtggttttca aagaggtaca ctggtatctt
    13021 atgactgcgg ataattatca tagtaagccc cagagagagg agttttttgt agattccgga
    13081 tattataaat ttcatgagat ctatcatctg ctgaggtttt caaacgagaa gcagatcgta
    13141 gagcgtgctt atcaggaata tttggagatg agaagcaatg gactctgggg aaaacagcat
    13201 aagtattatt aacgagagaa cagggctgtg tttttttgca acgcagcccg gtttaaattt
    13261 tggagaaaat ggaaatactg taactgaagt gttatagaaa cgggagaggg tgtaagatgc
    13321 tgaaatggca ggagaatttt cttgcagggg aatctgtaaa ggatcctgag aagataaaaa
    13381 agaaactgaa cagcggaaaa ccggttctgg gcatttatct ccttactctg tcagagaatc
    13441 ctgtgaatct gatggatatt attcctgcag caatgctgat acagaagagt ttttatggaa
    13501 tctgtccgaa gatcatagga atggcgaagg gcaaagagga agccttggag atggtgcgaa
    13561 gtctgatcga tgaaatgtac agggaaacgg gaaccttcgc aacagctgaa tatatagaaa
    13621 acaggtgaga atatgttaca tattttatgg ctgatcctta aatttatact gatcatcctg
    13681 ggaattctgc tgggccttct tttactggca gttcttcttg tactgttctg tcctgtaaga
    13741 tataaggcat cagctgtcaa ggcagaaggt ggctggaaac agacagaggg agagggtatc
    13801 gtaagctggc tgtttcatgg gatttcgctg agagcggaat ggaaagatca gcagatggag
    13861 atatcctttc atctgtttgg aattcccgta gacaagttgt tgaaaaaacg gcaggagaag
    13921 agggctataa caaagaaatc cgggaaaaat ccggagaaat ccggcgcaga aaaggtatct
    13981 gtatccggca tagacggaaa cagggaagaa gagcataaaa aatcagtggt tgatcacccg
    14041 aaatcagaga atatggagac tgaggatctg aaaacagaca gaaattcagc ttcaggtaca
    14101 tctgctgata cagagaggat cagaaacagt cagatatccg gacagcagga actgaatgca
    14161 gatgatacag atcggaatag tctaaagaag aggcagtttt ttataaaagg gatctatgac
    14221 cggatccgaa atatttttca gtcgattcgt acaaaactgc aaaatatccg caggacattc
    14281 gggaagatta agaagaatgt gtcctggtgg aaggcgttta tagaacatcc cagagtgaca
    14341 gctgccagaa aacttgtatg gaaacatgga aaatttttgc ttaagcatat ttttcctaca
    14401 aggatagaag ggcaggttac tttttctttt gaagatccgg cgctgacagg tgcggcactt
    14461 gctgtacttg ggatgacaat tccatttcac aaaaactgta tacagatcga tccccgcttt
    14521 gacagtgaga attatctgta tggaaacatc agggcaaaag gcaggattta cggatttgtt
    14581 cctgtgcggg cagcagtgag tatttatttc aataaaaata taaaatacgt tataaaacgt
    14641 tggaaaacca ggagggcatg accatggcaa atgaaaacaa ttttaaagaa accgtaaatt
    14701 cattattcaa gggaatggac agttttattt ctgcgaaaac agtggtagga gaggcaatcc
    14761 atgtaggcga tacgatcatt cttcctctga tggatgtatc tttcggtgta ggtgccggtg
    14821 ctttttccgg agagaagaag gataacggcg gcggcggaat ggcaggaaag atgactccct
    14881 gtgcagtgct tgtgatccag aatggaacaa caaagctggt caatgtgaaa aatcaggatg
    14941 gtctcaccaa gatccttgat atggttccgg attttgtaga ccgttttacc tccggaaaag
    15001 gtgacgaaga atctgtcggc gaatcagaaa aataattttt gcatagacta tagcaaaccg
    15061 atgaaaaagg tgcagaagaa ttggaaaagc tgttcgg
//
