LOCUS       gnlProkkaCGNLHMDI_48   21374 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CGNLHMDI_48.
ACCESSION   gnlProkkaCGNLHMDI_48
VERSION     gnlProkkaCGNLHMDI_48
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 02:45:57
            Original ID  :: gnl|Prokka|CGNLHMDI_48
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 34982
            Orig. end    :: 56356
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21374
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11374]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11374
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21374
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21374
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             347..634
                     /locus_tag="ctg48_37"
                     /transl_table=11
                     /translation="MSTGLDSGLRINDNSILVECEVDSKYQYKLVIYDNTFDDNPLEKV
                     YAIRNIDYNITDGNKIANFIIKLEENNYDSKKVFSQLLRDYTKQFELILG"
     CDS             845..1162
                     /locus_tag="ctg48_38"
                     /transl_table=11
                     /translation="MDEEYDDWLVNDDGKNNINDLIKETVALETTGKTGFFYLDKKRTQ
                     NIFKKSGYQLPSRLKNSGSNIIIRTIDDSVNKKSIILLKANNLSDGSVIGKIALQKQVK
                     R"
     CDS             1362..1799
                     /locus_tag="ctg48_39"
                     /transl_table=11
                     /translation="MSTRELLARLLKCEAGGEGENGMRAVASVIVNRTRVPNGEFARVS
                     KGGDFRAIMEQPNQFTCLKTTVGGQYNPQNVYNIRPDEIHYNIADWALAGNTDSSVGNS
                     IFYFNPFSDTCPTFFPSNNGVIYNRVGDHCFYSPTEAYSKT"
     CDS             1814..2521
                     /locus_tag="ctg48_40"
                     /transl_table=11
                     /translation="MDNSSNMAVNTTPMSNQINPEHHYGLDKNKACLNNSCPSNTSDIG
                     CYIPAIDEIMRHNQGAPSVAHPNMTEKVQKSNDNPSLEQAEIAYEEGGSTSEEQPENIN
                     KYNGSLQNIPFIKNLKKIDTSIPVLPATPATTASSGATVATPIRQNIGMSMSDYQYPFP
                     VTAENLRYHNGFMRTQIGRRITVDFLMGANTIVQKTGYLLGVAQDYILINEIDTNDITT
                     CDYYNIKFIRYYY"
     CDS             2761..4305
                     /locus_tag="ctg48_41"
                     /transl_table=11
                     /translation="MFCEKCGNKLSEGDAFCEKCGAPVPQENPVTTEDNGVNQNNQQFT
                     QPVNFDNNANVTEGVQQAAQPYQVQSQPKVKKPFPTKLVVICGAAAVVIAGIIITLCTL
                     IPYLNRIKLDDYIKVEFDKGSLYNGYASADIYIDSDTIEKEKVSDDKKSDIDYGKYADN
                     ISKGDWGSVLNDAVDDYSASQASVSSILDYCNVKAYLKDAKTESTTEDSDSFYTVSSAT
                     IDNISKDDTIVVELKWDDSESAKKHISEYEKTLGIQFDKSDVKKELKVSDILKEKKISL
                     KDMVEVDIINHIVDNNLIKTYGIKDGELSIDIAKFDYKVDDYKLKYESGSTISVYDKND
                     DFVDDFYLSIDGSQNYLDEGDEVTFKAEKKIIPNTSLIIKDSSTTVTAKANNVMTSDEA
                     KANVDKINSAVNDYIDEYYSSLTSYSPVEMYYVQPKKASDDERAFILVVEKGKYDGWFD
                     SYDTYYCGIYIKNPYLLDDEVYFSSIDSSSGDQKLADYKKYESFLDSKNYTATKIS"
     CDS             4383..5282
                     /locus_tag="ctg48_42"
                     /transl_table=11
                     /translation="MKFCKYCGAQLEDNAVCNCEKSRAAQAQAQQANAQAQPQYQQPVQ
                     PQQPQYQNPVQQQYAQPQNPQTQQSPYAVNNTAPIGENAFVKALKNIPVVFTSFFKDSK
                     TVIKTAKAEKDIILGALFSAIFFIALILGNMFLMLSMSALDFPKTLLVSLVTTVLIGGF
                     YSVILFAYVKKYKTEENTAKAFIDSFITFSIESIPASIGWILAGLCALISVYMFLFFFV
                     IVMLYLVISLVNQVKANVPEAKNSALFTLILTLIVAVAFMIVFFIGAELTMWSFNTSTF
                     ATSVLTSLIGGGSYSSLY"
     CDS             complement(5342..6526)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_43"
                     /sec_met_domain="PF04055 (E-value: 3.8e-20, bitscore: 64.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFPIFSYTFQIEAETCVSASKSFMRFFMSNSIGLYIHIPFCKHK
                     CPYCDFFSGNADENDFDNYVIELKDKIKYWSEKTKRDVATVYFGGGTPSVLGADRLCDI
                     LDFIKFNFNIQNNAEITVEVNPDSAKTIDFEKMYACGFNRISMGMQTAVEDELRLLGRI
                     HSIDDAKTSVERAKSAGFNNISLDLMMGIPNQTIESLEKSISFCADCKVTHISSYILKI
                     EENTPFYKVQNKLKLADDDMQAEMYLKAVEMLDSLGYKQYEISNFAKQGYESRHNTNYW
                     RCGEYVGIGPSAHSFFEGKRFFYSRSMDNFYNNKLSFEGTGGDEEEFIMLSLRLKSGLN
                     YSEFEEKFGYTLPSYIIKKAKEYEKYGYTNVTDKSISFTPKGFLVSNSIISELI"
     CDS             6692..8278
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 109.2; E-value:
                     4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_44"
                     /transl_table=11
                     /translation="MSSFKEEISKRRTFAIISHPDAGKTTLTEKLLLYGGAINLAGSVK
                     GKRTAKHAVSDWMEIEKQRGISVTSSVLQFKYNGYCINILDTPGHEDFSEDTYRTLMAA
                     DSAVMVIDGSKGVEKQTIKLFKVCVMRNIPIITFINKMDRDAKNSFDLLEDIENVLGIH
                     TYPVNWPIGSGKEFKGVYDRNSKKILAFTANNGQKEVEKKELTLDDPALEDTIGYYHKQ
                     DLFDEIELLDGAGDEFDLEAVRNGQLTPVFFGSALTNFGVEPFLEQFLQLTTPPLPRET
                     VDEKVEPMSDFFSAFVFKIQANMNKAHRDRVAFMRICSGKFEKNMEVFHVQGNKKMRLS
                     QPQQIMAQEREIVDEAYAGDIIGVFDPGIFSIGDTICSPGHKVQFRGIPTFAPEHFALV
                     RQKDTMKRKQFIKGTSQIAQEGAIQIFQELDAGMEEVIVGVVGVLQFDVLKYRLQNEYN
                     CDIIMETLPYEFIRWIVNDDIDPKTLDLASDTKKIQDLKGNHLLLFTSYWSINWALEHN
                     KGLELAEFGTN"
     CDS             8302..9705
                     /NRPS_PKS="Domain: Aminotran_5 (54-217). E-value: 1.7e-13.
                     Score: 42.1. Matches aSDomain:
                     nrpspksdomains_ctg48_45_Aminotran_5.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_45"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.6e-12, bitscore:
                     36.7, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.4e-09,
                     bitscore: 28.8, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 6.8e-13, bitscore:
                     40.1, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLYDKLKNYSKSGIYPFHMPGHKRTDITEEGIIPYNIDITEIHDF
                     DNLHSPNGVIDEIQKKAAKLYNAKNAFILINGSTGGILSAIRSMTNQGDKILMARNCHK
                     SVYNAAELFNLNVDYIFPDTDSRYNILTSVSPCYIEDKLTKHNDEIRLVIITSPTYEGV
                     VSDIKSISEICHKHGAKLLVDEAHGAHFSFSDNFPDEALNCGADAAVLSLHKTLPSLTQ
                     TALLITNDSELSEILAENLAVFETSSPSYILMSSIEKCLDFCENSKDKFKEYCCNLKTV
                     REKLENLKYLKIYDKSDTDFDYDIGKIVISTANANISGTKLAEILRNNYQIETEMAYSD
                     YVIAMTSVCDTEKAFDMLSDALISIDSELSKGADTERVPLKNLYTGKNFNACELYKFNK
                     ETIPFQNSEFRTSAEYIWAYPPGIPLIVPGEIISKELINYIEYLSACKIEIMSTKGGMT
                     DNISVVKKD"
     aSDomain        8464..8952
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg48_45_Aminotran_5.1"
                     /evalue="1.70E-13"
                     /label="ctg48_45_Aminotran_5.1"
                     /locus_tag="ctg48_45"
                     /protein_end="217"
                     /protein_start="54"
                     /score="42.1"
                     /tool="antismash"
                     /translation="IDEIQKKAAKLYNAKNAFILINGSTGGILSAIRSMTNQGDKILMA
                     RNCHKSVYNAAELFNLNVDYIFPDTDSRYNILTSVSPCYIEDKLTKHNDEIRLVIITSP
                     TYEGVVSDIKSISEICHKHGAKLLVDEAHGAHFSFSDNFPDEALNCGADAAVLSLHKTL
                     "
     CDS             10001..11374
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_46"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 6e-31,
                     bitscore: 98.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.3e-14, bitscore: 46.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.3e-14, bitscore: 46.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.8e-20, bitscore:
                     63.8, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQYKLNGYNIVLDVYSGSVHAVDDLAYDVIAMYKNATKEQIID
                     EMLSKYADNPEITKEEISDCIDDVKELEEQGKLFTDDKYENLAFDFKKRNTVIKALCLH
                     IAHTCNLNCEYCFASQGKYHGERALMSFEVGKRAIDFLIENSGSRVNLEVDFFGGEPLM
                     NFDVVKQIVAYARSIEKEHNKNFRFTLTTNGMLVDDDVIEFANKECHNVVLSLDGRKEV
                     HDHLRKTVNGKGSYDIIVPKFQEFVKKRGNKGYYVRGTYTHNNTDFTNDIFHMADLGFT
                     ELSMEPVVCAPDDPYALTYDDLPILFEQYEILAKEMLKREKEGRPLTFYHYMIDLTGGP
                     CIYKRISGCGSGTEYMAVTPWGDLYPCHQFVGDEKYKLGDIFNGVSNTKIQDEFKLCNA
                     YARPDCKDCWARLYCSGGCAANAYHATGSITGIYEYGCELFRKRMECAIMMKVAEAEE"
     CDS             11440..12249
                     /locus_tag="ctg48_47"
                     /transl_table=11
                     /translation="MNEKIIMLGTGSAMVTDCYNTCFLLKSENDCLLVDAGGGNGILSA
                     IKKSGIAWNSIKTMFITHSHTDHILGAVWVIRQISALMNSGKYDGDFNIYCHDECVDSI
                     TAICNHTLAPKFLKNINTKIFINEVKDGERQNAGSIRLTFFDIFSDKTKQFGFKAVFPS
                     GKVLACLGDEPFNEKCRNFVQNCDYLMCEAFCLYSQKDIFKPYEKFHSTALDAGKLAES
                     LFAKNLILYHTEDETLQTRKSTYTSEARTVFNGNIFVPDDFEVIDLK"
     CDS             complement(12241..14154)
                     /locus_tag="ctg48_48"
                     /transl_table=11
                     /translation="MFSTDKSSFNKKDVSDCDYKISLAGNPNVGKSTIFNELTGLRQHT
                     GNWTGKTVEFARGCCKIKDARFCITDLPGCYSLLSFSGEEAVTRECLIQNQNDCVVIVV
                     DCGVIERNLSFALQVLSVTKNAVLCLNLCDEAEKNGIKIDCDELSLNLGIPVVKTCATD
                     KKGLDELKKAIYNVCSGKIKCFRVERNFEGVDILSEKNYKQNIEKLSQIGNKISSDCVK
                     YEKSELNTCTRKLDKILTSKTTGIPIMLAMLGILFWITVVGANYPSEWLSNLFGFIKEK
                     LYILFDFLYAPDVVTGLLIDGVYTTLSWVVSVMLPPMAIFFPLFSLVEDSGYLPRIAFN
                     LDRYFSKCGAHGKQSLAMAMGLGCNACGVTGCRIIESPKERLIAILTNNFMPCNGRFPT
                     IIALLLMFFAGTAFKLSSSLEVAALLIGIIVFCVFITLVISKVLSVTILKGEQSGFVLE
                     LPPYRKPQILKTIVRSLLDRTLFVLGRAVAVAAPAGAIIWILANVHISDVSLLKYCTDF
                     LDPFGRFIGVDGVIIMAFILGFPANETVIPIIIMSYMASGTLVDYSSYDQLFQLLSMNG
                     WTITTAVCTIILCILHYPCSTTCLTIKKETGSLKWTLVSMALPTAMGIVLCMITAGVMG
                     LF"
     CDS             complement(14170..14406)
                     /locus_tag="ctg48_49"
                     /transl_table=11
                     /translation="MKEKCSLDKLPLGVTGIVYRVNCNENIKNRIFDFGIMENSSVIPL
                     FTSPFGDPSAYLVKNAVVALRNNDCKDIIVTPE"
     CDS             14874..16763
                     /locus_tag="ctg48_50"
                     /transl_table=11
                     /translation="MNKSFKKILSIVLSVMMISSLMTVSLSVSAVEDGKVRVIVRNDTY
                     SVENGAPWDGVLVDEWVSINNDTTMMSAVADALNNHGYTQEGAENNYISSINGLAAFDG
                     GTMSGWMGTLNDWFTNSGYASYTVADGTLESGDEIAIMYTSNGYGEDIGGTWANNDTTV
                     KSVEITGAELSGEFDPSVTDYTLTIDTPSADVNVVPTATNKNFQTRKYKNEYLPSDDSA
                     FYKRSQTVNVSDGDKIFIGCGDIAWPSMNTSEGGTVYTFTVKYAPSAADTVSNKIDEVA
                     EYLASQDTPTVSSVGGEWTVLGLARAGKITDEIADGYYQNAVKYVEEKGSAKLHNTKST
                     DNSRVILALTAIGKDVTDVASYNLLEPLADMDYVKKQGINGPVFALIALDTGDYEIPQT
                     DAANPTTREKLVQTILDAQVANGGWTFFGSTADPDMTGMAIQALAPYYSTNSDVKEAID
                     KALTAMSNAQNENGGFASWGSVNSESCAQVLVALTSLGIDPTNDERFIKNGNTLIDAMM
                     SFSAENGFGHTDTTYNQMATEQGFYAFVSFDRLVNGKTSLYNMTDRLAENYAVGDVNLD
                     NTVSVIDATLVQKQIVNLEQLSKVSLIKADVNHDGVIDVVDATEIQKIIVKLV"
     CDS             16790..17719
                     /locus_tag="ctg48_51"
                     /transl_table=11
                     /translation="MEKIKKFVKKNQILLIAVCVCIAALTVAFFAGGNRSENKVQTAST
                     ASSLSTTNADTETTSVSATEKTTQNPTDSAKSNKDKKDRKNSEDKKNSKDNSQNSNGSA
                     VEKSEKSEQSSNNSSSDKNKPSSSSNSSSKPNKKNDVQPTTQDKYKTDPVPSGKPKPVE
                     PEEQETKDTNLYCTFTITCSTILDNIDDLDPEKIELVPKDGIILKKQKVQFKEGESVYD
                     VLVKVCKDNNIHMESSWTPMYNSAYIEGINNLYEFDCGSLSGWMYKVNEWFPNYGCSRY
                     VLKNGDDVVWCYTCNLGYDVGGGYATGE"
     CDS             17722..18612
                     /locus_tag="ctg48_52"
                     /transl_table=11
                     /translation="MKDTFSNMHPFINFIFFALTIGFTMFIMNPVCLAVSFLCALVTAL
                     YLNGKKAVRLSLVFLLPMILLIVLVNPVFNHEGMTILTYFPWDNPLTLESIVYGIASAF
                     LLSSTVLWFSSFNAVITSDKVVFLFGRIMPSLSLVISMALRFVPRFSAQMKLVRSAQHT
                     IGRDINEGTLFQRIRNAVKILSIMITWSLENAIETADSMKSRGHGLKGRTSYSLYKFDK
                     RDAFMLCTILFTGLVLMILLFTNAIKFRYYPSIKGDLFTVQSIIFYIFYTFLMLIPLSV
                     NIGEGIKWKHMQSKI"
     CDS             18585..21245
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 170; E-value:
                     1.1e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg48_53"
                     /transl_table=11
                     /translation="METYAIKNLSFRYPETGIDVLKDITFSVNEGEFITVCGPSGCGKS
                     TLLRHLKPDLSPHGVLSGEIFFEEKPISDLSHREQSSKIGFVMQSPENQIVTDKVWHEL
                     AFGLESLGYDNNTIRKRVAETASFFGIQNYFEKSVLELSGGQKQILNLASIMAMQPSVL
                     ILDEPTSQLDPIAASEFLHCVSRINHELGTTVIITEHRLDEVLPLSDRVLVIENNGISA
                     FDSPQKVGKILKEKNSKTFLSMPAPMQIWQAVTENDNTDCPVTVPSGKKWLSEYAQNHK
                     MYELKPENILKHSDKEAVSLNDIWFRYEKSGADVLKGLSLKIYQGEFAAILGGNGMGKS
                     TALSIICSLNKPYRGKVEISPLIKNSFDTLVAVLPQNPQTLFLKKTVLEDLYEVFDGRK
                     ISKEEKERRVTAAVKLCRLESLCNRHPYDLSGGEQQRAALAKILLIRPQILLLDEPTKG
                     LDAEFKIEFAQIIYDLNKAGITVLMVSHDVEFCAVYPSRCLMFFNGEVVSEGTPRTFFS
                     SNSFYSTSASRMSKGIIDNAVSSNDVIYACTGKSRDISIDRNTPDIDLFKNDTENIPLQ
                     KSKAENKKLSVFKKIFGFFGAVLFILGLIINLEYIPNFSAKTLPTWFNWGIIGVSVALL
                     MIAFGTKSKRPIDLPRKSSKLSKRTVSMAIMVLLAIPVTIFVGMTYLQDQKYLFISLLV
                     MIECMIPFFLVFEGRHPKARELVIISVLCAIAVAGRLAFTMLPQFKPVVAIVIISGVAF
                     GGESGFLVGAVSMLVSNLMFGQGPWTPWQMFAAGIIGFIGGILFKKGLLGRTRTSLCIY
                     GFIATMVIYGGLMNLYSALTSHSAFNLNMLITFYVQGFPMDIVHAVSTVIFLFFGAEPM
                     LEKLDRIKVKYGLIE"
ORIGIN
        1 cagtatttat cggaataata aagcggatat aacgggttcg aatccctccg tctccgccat
       61 aaaaaacacc gtagttctgt tagaattacg gtgttttttg ctcaatatca atagtcgggg
      121 ggtaatccga aaaaatcgag tatatttata agtggctaat tattttcacg ccctgtattt
      181 attgataagt ataatctaaa aatcctgtta tgattgcagt accatttctt tttgatattc
      241 attgcattct aacttggtaa tattaggatt tgaaataaat cctaaacacg gtggaaagtt
      301 ctctgaagtc ttaacggcag aagaatggcg gaaattcacg cacgctatgt caacaggact
      361 tgattcggga ttaagaataa atgataactc aattcttgtt gagtgtgaag tggactcaaa
      421 gtatcaatac aaattagtta tctacgacaa tacttttgac gataatcctt tagaaaaggt
      481 ttatgcaatc cgaaatatag attataatat aaccgatggc aacaaaatcg caaattttat
      541 aattaaatta gaggaaaaca attatgatag caagaaagta tttagccaat tactcagaga
      601 ttatactaaa cagtttgaac ttatactcgg ataatacaac attaagagta agcaattcaa
      661 tgacatcgga cgaaactctg ttaaaaatgg aagagttaat gaaggacaat ccaacagagc
      721 aggagttaat caagagattg ggcaagaact ttccgcagga gtaaaagaaa aattctcgct
      781 tgatgaagat tatgatttta cagatgaaaa agccagtgta atacacgata cgctgaaatt
      841 tttaatggac gaagaatacg atgattggct tgtgaacgat gacggcaaaa acaacatcaa
      901 tgatttaatc aaagaaactg ttgctttaga aacaacaggg aaaacaggat ttttttattt
      961 agacaaaaaa agaacccaga atatttttaa gaagtcaggg taccaattac ccagccgact
     1021 taaaaattcg ggttccaata tcattatacg cactattgat gatagtgtca ataaaaaatc
     1081 aataatatta ctcaaagcaa acaatttatc tgatggttcg gtgattggca aaatagccct
     1141 gcaaaagcaa gtaaagcggt agacagcaac agctaatctg aataaatgtt gtagttggca
     1201 tctcaaaaga ttatcgaaca ccgtctgatt tgcttctata aaacagaatt ttctgtctgc
     1261 gtgaataaca catttatcac aagctttttc gttgtaacaa caagttattt tatgcataaa
     1321 atatcattga ataaaataac ggttggtgaa aaaaggtggc attgagtaca agagaattgc
     1381 ttgcaagact tttaaaatgt gaggcaggtg gggaaggtga aaacggaatg cgtgccgttg
     1441 cgtcggtaat tgtaaaccga acccgtgttc caaacgggga atttgcaaga gtcagcaagg
     1501 gcggagattt ccgtgccata atggaacaac caaatcaatt tacctgtctt aaaacaactg
     1561 tcggaggaca atataatcct cagaatgttt ataatatacg ccctgacgaa attcactata
     1621 acattgccga ttgggcattg gcgggcaata ccgattcatc tgtcggaaat tcaattttct
     1681 attttaatcc attttcagat acctgcccaa cattttttcc gtcaaacaac ggagtaattt
     1741 acaacagggt aggggatcat tgcttttatt cgcctaccga ggcttattcc aaaacataaa
     1801 ggagcatagc ttaatggata attcttcaaa tatggcagtt aatacaactc ctatgtcaaa
     1861 tcagattaat cccgaacatc attacggact tgacaaaaac aaagcctgcc tcaacaattc
     1921 atgtccgtca aacacatcgg atatcggatg ttatattcct gcgattgacg aaattatgcg
     1981 acacaatcag ggcgcaccgt ctgttgcaca ccccaatatg acagaaaaag ttcaaaaatc
     2041 aaatgacaat ccctcgcttg aacaggcaga aatagcatat gaagagggcg gaagtacatc
     2101 agaagaacaa cctgaaaata taaataaata caacggaagt cttcaaaata taccgttcat
     2161 taagaactta aaaaaaatag atacatctat acccgttttg cctgcaaccc ctgctacaac
     2221 ggcgagctcc ggtgccaccg ttgcaacgcc gataaggcag aatatcggaa tgtcgatgag
     2281 tgattatcaa tatccgtttc ctgtaacagc cgaaaatctg agatatcaca acggttttat
     2341 gcgaacacaa atcggaagac gaatcaccgt tgattttctc atgggagcaa acacaattgt
     2401 tcagaaaaca ggctatcttt taggtgttgc tcaggattat atccttataa atgagattga
     2461 caccaacgac atcacaacct gtgattacta caatataaaa tttataaggt attattacta
     2521 aaccacagcg gcaaaaacta aagtttatag tttttgccgc tgttttattg taattatttg
     2581 ctatgtgtac atcatttcat tattttaaca tataattttc tatagtgtaa aaaattaaaa
     2641 aattttaaga aatattgaat tattgctgta atttgtgata taataagtgt ggtgatgtta
     2701 tcgctttaca atgctaaagt gataatattc attatattat caaacattgg agatgaattt
     2761 atgttctgtg aaaaatgcgg caataagctt agcgagggag atgctttttg cgaaaaatgc
     2821 ggagctcctg ttcctcagga aaatcccgtt acaacagaag acaacggagt aaatcaaaac
     2881 aatcagcagt tcacacaacc tgtaaatttt gacaacaatg ctaatgtcac agaaggtgta
     2941 cagcaggcgg cacaaccata tcaggttcag agtcaaccaa aagttaagaa gcctttcccg
     3001 acaaagcttg ttgtaatttg cggtgcggca gcagttgtaa ttgcaggaat aatcattaca
     3061 ctttgcacac ttattccata ccttaacaga attaaacttg atgattacat aaaagttgaa
     3121 tttgacaaag gttctttgta caacggttac gcttctgctg acatttacat tgacagtgat
     3181 actattgaaa aagaaaaggt ttctgatgat aagaaatcag acattgatta cggcaagtat
     3241 gccgacaata tttcaaaggg cgactgggga agtgtgctta acgatgcagt agatgattat
     3301 tctgcaagtc aggcatcggt ttcatcaatc cttgattact gcaatgtaaa ggcatatctc
     3361 aaagacgcta aaacagaatc aacaacagaa gattcagata gtttttacac agtttcatca
     3421 gcaaccatag acaacatcag caaagatgac acaattgttg ttgaactcaa atgggatgac
     3481 agtgagtctg caaagaaaca tatttccgag tatgaaaaaa ctctcggaat tcagtttgac
     3541 aagagtgatg tcaagaaaga gctcaaagtc agcgacattc ttaaagagaa aaaaatctca
     3601 ctcaaagata tggttgaagt ggatataatc aatcatatag ttgacaacaa ccttatcaaa
     3661 acttacggta taaaagacgg tgagctttca atcgacatcg ctaagtttga ctacaaagtt
     3721 gatgattaca aacttaaata tgaatcaggc tctactatca gtgtgtatga taaaaacgat
     3781 gattttgtag atgattttta tctcagcatt gacggtagtc aaaactatct tgatgaaggc
     3841 gatgaagtaa cattcaaagc cgaaaaaaaa attattccaa acacctcact tattattaag
     3901 gactcgtcaa caacagttac tgctaaggct aacaatgtta tgacttccga tgaagcaaaa
     3961 gcaaatgttg acaaaataaa ttccgctgta aacgattaca ttgatgaata ctattcatct
     4021 ctcacatctt attctccggt tgaaatgtat tatgttcagc caaagaaagc atctgatgat
     4081 gagcgagcat ttatccttgt agttgaaaaa ggaaaatatg acggttggtt tgacagttac
     4141 gatacttact attgcggcat atacatcaag aacccttatc tgcttgatga cgaagtttat
     4201 ttctcaagta ttgacagcag tagcggtgat cagaaacttg ctgactacaa gaagtatgag
     4261 agtttccttg attcaaaaaa ttataccgca acaaaaattt cttaacccaa acaatcggtt
     4321 ttcaacaaac aacaggtagc tataagacct gttacatatt attttatctt ggaggaatca
     4381 ccatgaaatt ctgtaaatat tgcggagcac agcttgaaga caatgctgtt tgcaactgcg
     4441 aaaagtcaag agccgctcaa gcacaggctc agcaggcaaa tgcacaggca cagcctcagt
     4501 atcagcagcc tgttcagcca caacagccac agtatcagaa ccctgttcag caacagtatg
     4561 cacagccgca aaaccctcag acacagcagt cgccttatgc cgtaaataac acagcaccca
     4621 ttggggaaaa tgcttttgtt aaggctttaa agaacattcc tgttgtgttc acttcattct
     4681 ttaaggattc caaaactgtt atcaaaacag caaaggctga aaaggacatc attctcggcg
     4741 ctcttttctc ggcaattttc tttattgcac tcattcttgg caatatgttc cttatgcttt
     4801 ctatgagcgc acttgatttt ccgaaaacac ttcttgtaag tcttgttact actgtcctta
     4861 tcggcggctt ctattctgtt attctctttg catatgtaaa gaaatacaaa accgaagaaa
     4921 acacagccaa agcatttatt gattcattca tcacattttc aattgaatct attccggcat
     4981 caatcggttg gattttggca ggtctttgcg cattaatcag cgtatatatg ttcctgttct
     5041 tcttcgtaat cgttatgctt taccttgtta tttcacttgt aaatcaggta aaagctaatg
     5101 ttcccgaagc aaagaactct gcattattca ctttaattct cacactcatc gttgccgttg
     5161 catttatgat tgtattcttc atcggcgcag aacttactat gtggtcattt aacacaagta
     5221 catttgcaac aagtgttctt acatcgctca tcggcggcgg ttcatactct tcattgtatt
     5281 aatctgtcat acaaattcat aacataaaat taacgctccg aatttattct cggagcgttt
     5341 tttatatcag ttcactgatt attgaatttg aaacaagaaa acctttcggt gtaaagctga
     5401 ttgacttgtc cgtaacattt gtatagccgt atttttcata ctctttagct tttttgataa
     5461 tgtaagaggg gagggtgtat ccgaattttt cctcaaattc agaataatta agaccgcttt
     5521 tcagcctgag agagagcata ataaattctt cctcatctcc gcccgtacct tcaaaagaca
     5581 gcttattgtt ataaaaattg tccatgcttc tcgaataaaa gaaccttttg ccctcaaaaa
     5641 atgagtgtgc agacggacct atgccgacat attcaccgca tctccagtaa ttggtattat
     5701 gtcggctttc atagccctgt tttgcaaaat tagaaatttc atattgcttg tatccgagag
     5761 aatcaagcat ttcaacagct ttcagataca tttcagcctg catatcatca tcggcaagct
     5821 taagtttatt ttgaacctta taaaatggag tattctcctc gattttcaaa atgtatgatg
     5881 aaatatgagt aactttgcaa tcggcacaga aactgattga tttttcaagg ctttcaattg
     5941 tctgattagg aattcccatc atcaaatcaa gtgaaatatt attaaatccc gcacttttag
     6001 ccctttcaac agaagtcttt gcgtcatcaa tgctgtgaat tctcccaagc agtcttaatt
     6061 catcttcaac agcagtctgc attcccattg aaatgcgatt aaatccgcag gcatacattt
     6121 tttcaaaatc aatagttttg gcggagtcgg gattgacttc aaccgtaatc tcggcattat
     6181 tttgaatatt aaaattaaac ttgataaaat caagaatatc acaaagtctg tctgcaccca
     6241 aaacactcgg cgtaccgccg ccgaaatata cggttgcaac atctcttttg gttttttcag
     6301 accagtattt tattttatct tttaattcaa tcacataatt atcaaaatcg ttttcatctg
     6361 cattaccgct gaaaaaatcg caatacggac atttgtgctt acaaaacggt atgtgaatgt
     6421 aaagaccgat agaattactc ataaaaaacc tcataaatga ttttgaggca gaaacacaag
     6481 tttctgcctc gatttggaag gtatatgaaa aaataggaaa aatcacatta agtccttctg
     6541 taccaatata ttacaatata tttacaaatt tgtcaagttt ttgtagcaat tatttttctc
     6601 acattttctt cattctttat tgacatatac catccaaaaa tagtaaaata tagaattgtg
     6661 gatatactta acctccgaag ggaagaaaga tatgagttca tttaaagaag aaatcagcaa
     6721 gcgcagaacc tttgcgatta tttcgcatcc tgatgcgggt aaaacaacac ttacggaaaa
     6781 gctcttgctc tacggcggag caattaacct tgcaggttcg gtaaaaggca aaagaaccgc
     6841 aaagcatgct gtgtccgact ggatggaaat tgaaaaacag cgtggtattt ctgttacatc
     6901 atcggttttg cagtttaaat ataacggtta ttgcataaat attcttgata caccgggaca
     6961 tgaggatttc tcggaagata cctaccgtac acttatggcg gcagactctg ccgtaatggt
     7021 aattgacggt tcaaagggtg ttgagaaaca gactatcaaa cttttcaagg tctgtgtaat
     7081 gcgtaatatt cctatcatta cattcatcaa caagatggac agagatgcaa aaaattcttt
     7141 tgaccttctt gaagacattg aaaatgttct cggaattcac acctatcccg taaactggcc
     7201 aatcggttca ggtaaggaat tcaagggtgt gtatgacaga aattccaaga aaatccttgc
     7261 ttttaccgct aataacggtc agaaagaagt tgaaaagaaa gaacttacgc ttgacgatcc
     7321 tgcccttgaa gatacaatag gctactatca taagcaggat ttgtttgatg aaatagaact
     7381 tcttgacggt gcaggcgatg aatttgacct tgaagcagtc cgcaacggtc agcttactcc
     7441 tgtattcttc ggttcggctc ttacaaactt tggtgttgaa ccattccttg aacagttctt
     7501 acagctcaca actccacctc tgccaagaga aacagttgat gaaaaggttg agcctatgtc
     7561 agactttttc tctgcatttg ttttcaaaat tcaggcaaac atgaataagg ctcaccgtga
     7621 cagagttgca tttatgcgta tctgcagcgg caagtttgaa aagaatatgg aagtgttcca
     7681 tgttcagggc aacaaaaaaa tgcgtctttc acagccacag cagattatgg ctcaggaaag
     7741 agaaattgtt gacgaggcat atgcgggcga catcatcggt gtgtttgatc cgggtatttt
     7801 ctcaatcggt gacacaatct gttcaccggg acacaaggta cagttcaggg gaattcctac
     7861 atttgctccc gaacactttg cacttgtccg tcagaaagac acaatgaagc gcaaacagtt
     7921 catcaagggt acaagtcaga ttgcacagga aggtgcaatt cagattttcc aggagcttga
     7981 cgcaggtatg gaggaagtta tcgttggtgt tgtaggcgta cttcagtttg atgttcttaa
     8041 atacagactt caaaacgaat acaactgtga tatcattatg gaaacactcc catatgaatt
     8101 tatccgttgg attgtaaacg atgacattga tccgaaaact ctcgaccttg cgtcggatac
     8161 taagaaaatt caggatctta aaggcaatca tcttttgctc tttacaagct actggagcat
     8221 aaactgggcg cttgaacaca acaagggact tgaactcgct gagttcggta caaactaaat
     8281 atttaaaata tcggaggata tatgctgtac gacaagctta aaaattattc aaaaagcggc
     8341 atatatcctt ttcatatgcc cggacacaaa agaacggaca ttacagaaga gggtataata
     8401 ccgtataata tcgacataac cgaaattcat gattttgaca atcttcattc gccaaacgga
     8461 gttattgatg aaattcagaa aaaggctgca aaactttaca atgcaaaaaa tgctttcatt
     8521 ctgattaacg gttcaacagg cggaatactt tcagcaatcc gatcaatgac aaatcaaggc
     8581 gacaagatct taatggctcg taactgccat aaatctgtat ataatgcagc agaactgttt
     8641 aatctcaatg tcgattacat ttttcccgat acagacagca gatacaatat tcttacatcg
     8701 gtttcacctt gctatataga agataaactt acaaaacaca atgatgaaat cagacttgta
     8761 atcataactt cgcctacata tgaaggagtt gtttcggata taaagtcaat ctccgaaatc
     8821 tgtcacaaac acggagcaaa attacttgtt gacgaagctc acggagcgca tttttcgttt
     8881 tcggacaatt ttcccgatga agcacttaac tgcggtgcag atgccgcagt attgagtctg
     8941 cacaaaactt tgccgtcatt aactcaaact gcattgctca taacaaatga cagtgagctt
     9001 tctgaaattc ttgctgaaaa tttagctgta tttgaaacaa gcagtccgtc atatatttta
     9061 atgagttcaa tcgaaaaatg tcttgatttc tgcgaaaaca gcaaagataa attcaaggaa
     9121 tattgttgca atcttaaaac ggtcagagaa aaacttgaaa atctaaaata tctgaaaatt
     9181 tatgataaaa gcgatactga ttttgattat gatatcggca aaattgtaat ttcaacagcg
     9241 aacgcaaata tttcgggaac aaagcttgcc gaaatactgc gaaataatta tcagattgaa
     9301 accgaaatgg catattcgga ctatgtaatt gccatgacat cagtttgtga cactgaaaaa
     9361 gcttttgata tgctttcaga cgctctgatt tcaattgaca gcgaactttc aaaaggagcc
     9421 gacaccgagc gtgttccgtt aaaaaatctc tacacaggca aaaatttcaa cgcctgtgag
     9481 ttgtacaaat tcaacaaaga aactattccg tttcaaaatt cggaattcag aacttctgcc
     9541 gagtatatct gggcatatcc acccggaatt cccctcatcg tacccggtga aattataagc
     9601 aaggaactta taaattacat tgaatatctt tcagcctgca agattgagat tatgtcaaca
     9661 aaaggcggta tgacggacaa cataagcgta gttaaaaaag attgacaaat caatgactgt
     9721 gtgataatat taaactaaca aaatctaaca aggagtttga tttattatga agagaattaa
     9781 aactatcgaa actcgtgacc ttaagaagag cgttaagaca ggcggttgcg gcgagtgcca
     9841 gacttcatgt cagtcagcgt gtaagacatc ttgcggcgtt gctaaccagc agtgcgaaaa
     9901 gtgcatgagc gagaaataat tctattttaa tttgattatt aaggattatc gccgttttcc
     9961 caaagggtta acggctttcc ttttgtctaa cggagatatt atgattcatc agtataaact
    10021 taacggatac aacatagttc ttgatgttta cagcggcagt gtacacgcag tcgatgacct
    10081 tgcttatgat gttattgcaa tgtacaaaaa cgcaacaaaa gaacagataa tcgacgaaat
    10141 gctttcaaaa tatgcagata atcctgagat tacaaaagaa gaaatctccg actgcattga
    10201 tgatgtaaaa gagcttgagg aacagggaaa gctctttaca gacgacaaat acgaaaacct
    10261 tgcatttgac tttaaaaaga gaaacacagt aatcaaagca ctttgtctgc acattgctca
    10321 cacctgtaac cttaactgcg aatactgctt tgcaagccag ggcaaatacc acggcgagag
    10381 agcgctgatg agctttgaag tgggcaagag agcaattgac tttctcattg aaaattcagg
    10441 cagcagagta aaccttgagg ttgacttctt cggcggagaa cctcttatga actttgacgt
    10501 tgtaaagcag attgttgcct atgcaagaag tattgaaaag gaacacaaca aaaacttccg
    10561 ttttacactt acaacaaacg gtatgcttgt tgatgacgat gtaattgaat ttgcaaacaa
    10621 agaatgtcac aatgtagttc tcagccttga cggcagaaaa gaagtgcatg accatcttcg
    10681 caaaactgta aacggcaaag gcagttatga tattatcgtt ccgaaatttc aggaatttgt
    10741 caaaaaaaga ggcaacaagg gttactatgt aagaggtact tacacacata ataacacaga
    10801 cttcacaaac gatattttcc atatggcgga tttgggtttt acagagcttt caatggagcc
    10861 ggttgtatgt gctcccgatg acccatatgc acttacatat gacgatttgc ctatcctttt
    10921 tgaacagtac gaaattcttg caaaggaaat gctcaagcgt gaaaaagagg gcagaccgct
    10981 caccttctat cattatatga ttgaccttac aggcggtccg tgcatttata agagaatctc
    11041 gggttgcggt tcgggtacag aatatatggc tgtaacacct tggggcgacc tctatccctg
    11101 tcatcagttt gtaggcgatg aaaagtacaa gctcggcgat atctttaacg gcgtttcaaa
    11161 cacgaaaatt caggacgaat ttaagctttg taacgcatac gcccgtcctg actgcaaaga
    11221 ctgctgggca agactttatt gcagcggcgg ttgtgccgca aacgcttatc atgcaacagg
    11281 ctcaatcaca ggtatttacg aatacggctg tgagcttttc agaaaaagaa tggaatgtgc
    11341 cattatgatg aaggttgcag aagcagaaga ataaaattac aataaaattt tcaggcagat
    11401 acatttttct tgtatctgcc tgtattttcg aggtgctgta tgaacgaaaa aattattatg
    11461 ctcggcacag gaagtgcgat ggttaccgac tgttataata cctgttttct tctgaaatcc
    11521 gaaaacgact gtcttcttgt tgacgcaggt ggcggaaacg ggattttatc cgcaattaag
    11581 aaatcaggaa tagcttggaa cagcataaag acaatgttta ttactcattc tcacaccgac
    11641 catatattgg gtgccgtgtg ggtaataagg caaataagcg ctcttatgaa ttcaggcaaa
    11701 tatgacggtg attttaatat ttactgccac gatgaatgtg ttgattcaat cacggcaatt
    11761 tgcaaccaca cacttgcacc gaaattcctc aaaaatatca atacaaaaat tttcatcaat
    11821 gaagtaaaag acggtgaaag acaaaatgcc ggcagtatcc gactcacttt ctttgatata
    11881 ttttcagaca aaacaaagca attcggattc aaggctgttt ttccgtcagg aaaagttctc
    11941 gcctgtctcg gtgatgaacc gttcaatgaa aaatgcagaa attttgttca aaactgtgat
    12001 tatcttatgt gtgaagcttt ttgtctttac agtcaaaaag atatttttaa gccctacgaa
    12061 aaattccaca gcacagcact tgatgccgga aaacttgcag agagtctttt tgcaaaaaat
    12121 cttatcctgt atcacaccga ggacgaaaca cttcaaacac gcaaaagtac atatacttca
    12181 gaggcaagaa cagtttttaa cggaaatata tttgttcccg atgattttga agttattgac
    12241 ttaaaataat cccataacac ctgctgtaat catacaaagc acaattccca ttgcagtagg
    12301 caaagccata gaaacaagcg tccatttaag gctgcctgtt tcttttttta ttgtcagaca
    12361 ggttgttgaa cacggataat gaagaatgca aagaataatc gtgcatacag ccgttgtaat
    12421 cgtccagccg ttcatactga gaagttgaaa cagctgatcg tagcttgaat aatcaacaag
    12481 agtaccgctt gccatatatg acataattat aatcggaata acggtttcat tcgcaggaaa
    12541 tccaagtata aatgccatta ttataacgcc gtcaaccccg ataaatctgc cgaacggatc
    12601 taaaaagtca gtacaatatt ttaaaagtga aacatcgctt atatgcacat ttgcaagaat
    12661 ccaaattatc gcacctgccg gtgcggcaac cgcaacagcc cttcctaaaa caaataaagt
    12721 tctgtccaac agcgaacgga caatagtttt taaaatctgc ggctttctgt acggcggaag
    12781 ttcaagcaca aatccggact gttcgccttt caatattgtg actgaaagta ccttagatat
    12841 aacaagtgtt ataaaaacac agaaaactat tattccaatc aacaatgccg ctacctcaag
    12901 cgaactgctc agcttaaatg ccgtacctgc aaagaacatg agcagtaatg caattattgt
    12961 gggaaaccgt ccgttacacg gcataaaatt atttgtaaga attgcaatca gccgttcctt
    13021 tggtgactca ataattctgc aacccgtaac tccgcaggca ttacagccaa gccccattgc
    13081 catagcaaga ctttgctttc cgtgagcacc gcactttgaa aaatacctat caagattaaa
    13141 tgcaattctc ggcagatatc ccgaatcctc aacaagcgaa aacaacggaa agaatatagc
    13201 cataggcggc agcattacag ataccaccca tgacagagtt gtataaactc cgtcaatcaa
    13261 aagtcccgtt acaacatcgg gagcgtataa aaaatcaaaa agaatataca gtttctcttt
    13321 tataaaacca aacaaattgc ttaaccattc gctcggataa tttgcaccaa caactgttat
    13381 ccagaacaat ataccaagca ttgcaagcat aatcggtatt cccgtggttt tgcttgtaag
    13441 tattttatca agctttcttg tacaagtatt taactctgat ttttcatatt ttacgcagtc
    13501 acttgaaatt ttgttgccaa tctgcgaaag cttttcaata ttctgtttgt agtttttttc
    13561 ggatagtata tcaacacctt caaaatttct ttctacccta aaacatttta tctttccgct
    13621 gcatacatta tagatcgctt tttttaattc atccaaacct tttttgtctg ttgcacaggt
    13681 ttttacaaca ggtattccaa gatttagcga taactcgtcg cagtcgattt ttataccgtt
    13741 tttttcagcc tcatcacaaa gattaagaca aagaacagca ttctttgtga cagataacac
    13801 ctgcaatgca aatgaaagat ttctttcaat aactccgcag tcaacaacta ttacaacgca
    13861 gtcattttgg ttttgtataa ggcactccct tgttaccgcc tcttcgcccg aaaatgaaag
    13921 cagggaatag catccgggta agtccgtaat acaaaatctt gcgtctttga ttttgcaaca
    13981 acctctggca aactcaactg ttttacccgt ccagtttccc gtgtgctgtc ttaatcccgt
    14041 aagttcgtta aaaattgtac tcttgcctac attaggatta ccggcaagag aaattttgta
    14101 atcgcaatcc gagacatcct ttttattaaa agatgattta tccgtagaaa acaataaaaa
    14161 agcctccttt tattcaggag taacaatgat atctttgcaa tcgttatttc tcagtgccac
    14221 aacggcattt ttaacaagat acgcagacgg atcaccgaac ggacttgtaa acaaggggat
    14281 aacagaactg ttctccataa taccgaaatc aaatattctg tttttgatat tttcattaca
    14341 gttcacacga tagacaatcc ccgtaactcc aagcggtaac ttgtcaagcg aacatttttc
    14401 tttcatctga ttcaccgatt tcaacttttt attaacagca tattcaattc atacaactga
    14461 gttacacaaa aagccagcca taaactaaac ttatatcgta cccgaataaa ctctgatatc
    14521 agaaaaattt taaggaattg acacgactat aaacaggtgt tataattaaa tgcagatttc
    14581 aaatgtatat aacttaatat gggtttacgg ttcaaaatgc atcttgcaga gtagataaca
    14641 gagaattcgg tgagaatccg aagcaacagt cattactgta tttggcattg ccataagtca
    14701 ggtcgctgtc cgtatacctc ggattttgca aatcttggac agggaagagg tgcagccgac
    14761 catatctgta cagacttttg gtctgtatgg ttttgtttgt tgtgccttcc aaaaacggag
    14821 ggctttttta ttttgccttt cgatatacac aatacaatat ggaggaaaac actatgaaca
    14881 aatcttttaa aaaaatcctc tcaattgtac tttctgtaat gatgatttcg tcacttatga
    14941 cggtttcact ttcagtaagc gcagttgaag acggaaaagt aagagtaatt gtcagaaatg
    15001 atacatactc ggtagaaaac ggcgctccgt gggacggcgt tctcgttgat gagtgggtaa
    15061 gcattaataa tgacactact atgatgtcag cggttgctga tgcactcaac aatcacggct
    15121 acacacagga aggtgctgag aacaattaca tctcgtcaat taacggtctt gctgcatttg
    15181 acggcggtac aatgagtggc tggatgggaa ctctcaatga ctggttcaca aattcaggtt
    15241 atgcatccta tacagtagca gacggcacac ttgagagtgg tgatgaaatc gctattatgt
    15301 atacttcaaa cggttacggc gaggatatcg gcggtacatg ggcaaataac gatacaactg
    15361 ttaaatcggt tgaaatcaca ggtgccgagc tttcaggcga atttgatccg tcagttacag
    15421 actacacact cacaatcgac acaccgtcag ctgatgtaaa tgtagttcct actgcaacta
    15481 acaaaaactt ccagacaaga aaatataaga atgaatatct tccttctgac gacagtgcgt
    15541 tttacaagag aagtcagact gttaatgttt ctgacggtga caaaattttc atcggctgcg
    15601 gtgatattgc atggccgtca atgaacacaa gtgaaggcgg tactgtatat acattcacag
    15661 tgaaatatgc tccttctgca gctgacacag tttcaaacaa gattgacgag gttgcagaat
    15721 atcttgcatc acaagacaca cccacagttt cttcggtagg cggtgagtgg acagtcctcg
    15781 gtcttgcaag agcaggtaaa atcactgacg aaattgcaga cggttactat cagaatgcag
    15841 ttaagtatgt tgaagaaaaa ggttctgcaa aacttcacaa tactaaatca acagacaatt
    15901 caagagtaat tcttgccctt acggcaatcg gtaaggatgt tacagatgtt gcatcatata
    15961 accttcttga accgcttgca gatatggatt atgttaagaa gcagggtatc aacggtcctg
    16021 tctttgcact cattgcactt gatacgggcg attatgaaat tccgcagact gacgccgcaa
    16081 atcccacaac aagagaaaag ctcgtacaga caattcttga tgcacaggta gcaaacggtg
    16141 gctggacatt tttcggttca actgcagatc ctgatatgac aggtatggca attcaggcac
    16201 ttgctcctta ctactcaaca aacagcgatg ttaaagaggc aattgacaaa gcactcacag
    16261 caatgtcaaa tgcacagaat gaaaacggcg gatttgcatc atggggttct gtaaacagcg
    16321 aaagctgtgc acaggtactc gttgcactta caagccttgg aattgatcct acaaatgatg
    16381 aaagattcat caaaaacggc aacacactca tcgatgctat gatgagtttc tccgctgaaa
    16441 acggattcgg tcatacagac acaacataca atcagatggc aaccgaacag ggtttctatg
    16501 cttttgtttc atttgaccgt cttgtaaacg gcaaaacttc actctacaat atgactgacc
    16561 gacttgcaga aaattatgcc gtaggtgatg ttaatcttga caacacagtt tctgtaattg
    16621 acgcaacact tgttcagaag cagattgtaa accttgaaca gctttcaaag gtttcactta
    16681 tcaaagctga tgtaaatcat gacggtgtta tcgatgttgt tgatgcaaca gaaattcaga
    16741 aaatcatcgt taagctcgtt tgattaaagt tcacaagtaa aaattggtta tggaaaagat
    16801 aaaaaagttt gttaaaaaaa atcaaatact tttaattgcg gtgtgcgttt gtattgccgc
    16861 acttacagta gcattttttg caggcggcaa ccgatcggaa aataaagttc aaactgcatc
    16921 aactgcctcc tcgctatcga caacaaatgc agacacagaa acaacttctg tgtctgcaac
    16981 agagaaaacc actcaaaatc ctaccgattc cgctaaatca aacaaagata aaaaggacag
    17041 aaaaaattcc gaagataaaa agaacagtaa ggataattcg cagaacagta acggttcagc
    17101 cgttgaaaaa agtgaaaaat ccgagcagag ttcaaacaac agttcttcgg ataagaataa
    17161 accgtcttct tcatcaaaca gttcttcaaa accgaacaaa aagaatgatg ttcaaccgac
    17221 aacgcaggac aagtacaaaa ccgatcctgt accgtcggga aagccaaagc cggttgaacc
    17281 ggaagaacag gaaacaaaag atacaaatct ttattgtacc tttacaatca cctgttcaac
    17341 aattcttgac aatatagatg accttgatcc cgaaaaaatt gaactcgttc caaaggacgg
    17401 tataatcctc aaaaaacaga aggttcaatt caaagagggc gaatctgtat atgatgtcct
    17461 tgtaaaagtt tgtaaggaca acaatattca tatggaatcg agctggactc ctatgtataa
    17521 ttccgcttat attgaaggaa ttaacaacct ctacgaattt gactgcggtt ctctttcggg
    17581 ctggatgtac aaagtcaatg aatggtttcc aaactacggc tgttcacgat atgtactcaa
    17641 gaacggcgac gatgtggtct ggtgctacac ttgtaactta ggctatgatg tcggcggagg
    17701 atacgcaaca ggagaataat gatgaaggat actttttcaa atatgcaccc ctttatcaat
    17761 tttatatttt ttgcacttac aatagggttc acgatgttta tcatgaaccc tgtttgtctt
    17821 gctgtaagtt ttttatgtgc gcttgtaacc gctttatacc ttaacggcaa aaaagctgtg
    17881 agattgtcac ttgtttttct tttacctatg atactcttga tagttctcgt aaatcctgtt
    17941 tttaatcatg aaggaatgac tatactcaca tattttccgt gggataaccc actaacactc
    18001 gaatcaatcg tttacggtat tgcaagtgca tttttgcttt cgtcaacagt tttatggttt
    18061 tcttcattca atgcagtaat cacttccgac aaggtagttt tcctgtttgg cagaataatg
    18121 ccgtcattga gtctggtgat ttcaatggca ttgcgttttg ttccaaggtt ttcggcacaa
    18181 atgaaacttg tgcgtagtgc acaacacaca atcgggagag atataaacga gggaacattg
    18241 tttcaaagaa taagaaacgc agtaaaaatt ctttcgatta tgataacatg gtcacttgaa
    18301 aacgcaattg aaacagctga ttcaatgaaa agcagaggtc acggtcttaa aggcagaaca
    18361 tcctattcac tttataaatt tgacaaaaga gacgcattta tgctttgcac aatccttttt
    18421 accggattgg tacttatgat tttgcttttt acaaacgcaa taaaattcag atactatccg
    18481 tcaatcaagg gcgatttgtt tacggtgcaa agtattattt tttatatatt ctacacattt
    18541 ttaatgttga ttccgctatc ggtaaatata ggagagggga taaaatggaa acatatgcaa
    18601 tcaaaaatct gagttttcga taccccgaaa ccggtattga tgtacttaaa gatattactt
    18661 tcagcgtaaa tgagggcgag tttatcacag tctgcggtcc gtcaggctgc ggaaaaagca
    18721 cacttctcag acatctgaaa cccgatcttt caccgcacgg tgttctttcg ggagaaatat
    18781 tctttgaaga aaaacctata tcagaccttt ctcacaggga gcaaagcagt aaaatcggct
    18841 ttgttatgca atcacctgaa aatcagattg ttaccgataa ggtatggcac gaacttgctt
    18901 tcgggcttga aagtcttggt tatgacaaca atacaatccg aaaaagagtt gccgaaacag
    18961 cttcattttt cggaatccaa aattattttg aaaaaagcgt tctcgaactt tcgggcggac
    19021 aaaagcaaat tttaaacctt gcttcaatta tggcaatgca accgtccgtt ctcattttgg
    19081 atgaaccgac aagccaactc gatccgattg cggcaagcga atttttgcac tgcgtttcac
    19141 gcataaatca cgaactggga acaacagtga taataacgga acacagactt gatgaggtgc
    19201 ttccgctttc agacagggtg cttgtcatcg aaaacaacgg aatttcagct tttgactctc
    19261 ctcaaaaggt cgggaaaatt cttaaagaaa aaaacagtaa aacatttctt tctatgcctg
    19321 ctccgatgca gatatggcag gctgttacag aaaatgacaa taccgactgt cccgtaactg
    19381 ttccaagcgg caaaaagtgg ctttcagaat atgcccaaaa tcataaaatg tatgagctca
    19441 aacccgaaaa tattctgaaa cactctgata aagaagcagt aagtcttaat gatatttggt
    19501 tcaggtacga aaagtcgggt gcagatgtac taaaaggtct ttcactaaaa atatatcagg
    19561 gggaatttgc ggctatactc ggcggtaacg gtatgggaaa atcaaccgct ttgtcaatta
    19621 tctgttcact taacaagcca tacagaggca aagttgaaat ctctccgctt atcaaaaatt
    19681 cttttgacac gctcgtagca gtattaccgc aaaatccgca gacactgttt ttgaaaaaaa
    19741 ctgtacttga agatttatac gaagtatttg acggcagaaa aatcagcaag gaggaaaaag
    19801 aaagacgggt taccgcagcg gtaaagctgt gcagacttga aagtctctgc aatcgccatc
    19861 cttatgattt atccggcggt gaacagcaga gagcggctct tgcaaaaatt cttctcataa
    19921 ggcctcaaat tcttttgctt gatgaaccta caaagggact tgatgccgaa ttcaagattg
    19981 agtttgctca gattatatac gacctcaata aagccggcat aaccgttctc atggtaagtc
    20041 acgatgtaga gttctgtgct gtatatccaa gccgctgtct gatgtttttt aacggtgaag
    20101 ttgtgtcaga aggtacaccg agaactttct tttcatcaaa cagcttttat tccacctctg
    20161 caagccgaat gtcaaaaggc ataatagata acgcagtatc atcaaatgat gtcatatacg
    20221 cctgcacagg caaaagcaga gatatttcta tcgacaggaa cacacctgat attgaccttt
    20281 ttaaaaacga caccgaaaat attcctctcc aaaaaagcaa agctgaaaac aaaaagctat
    20341 ctgtttttaa aaaaatcttc ggattttttg gcgcagtact gttcatactc ggtctgatta
    20401 taaacctgga atatattccg aatttttcag ccaaaacttt gcctacctgg ttcaactggg
    20461 gaataatcgg agtatctgtt gcgttgctta tgattgcttt cggaacaaaa tcaaaacgac
    20521 cgattgacct gccgagaaaa agttcaaaac tgagtaaaag aaccgtcagt atggcaatta
    20581 tggttttgct tgcaattcca gttacaattt ttgttggaat gacatatctt caggatcaga
    20641 aatatctttt tatttcactc cttgttatga ttgagtgtat gattccgttt tttcttgttt
    20701 ttgaaggcag gcacccaaaa gcgagagagc ttgtcataat ttctgttcta tgtgcaatag
    20761 cagttgcagg acgacttgca tttacaatgt tgcctcagtt caagcccgtt gtggcaattg
    20821 tgataatttc gggagtagca ttcggcggtg aatcgggatt tcttgtcggt gctgtaagta
    20881 tgcttgtttc aaatcttatg ttcggtcaag gaccttggac gccgtggcaa atgtttgcgg
    20941 caggaataat aggcttcatt ggcggtattc tctttaagaa aggtcttttg ggcagaacaa
    21001 ggacttcgct ctgtatatac ggtttcattg ccacaatggt catttacggc ggacttatga
    21061 acctttattc ggcactcaca tcacattccg catttaatct aaatatgctc ataacttttt
    21121 atgttcaggg ctttccgatg gatattgttc acgcagtttc gactgttata tttctgtttt
    21181 tcggagcaga acctatgctt gaaaagcttg acagaattaa agttaagtac ggacttatcg
    21241 aataaaccta aacagcagat aaaatttctg ctgttttttt gtgctgtaat tcaaaaattt
    21301 tcgacaaaag tatagacata atccgaaaat aatattataa ttttgatgtg tctgatttta
    21361 atcaagcagt attt
//
