LOCUS       gnlProkkaNAGKNJKB_111  16247 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NAGKNJKB_111.
ACCESSION   gnlProkkaNAGKNJKB_111
VERSION     gnlProkkaNAGKNJKB_111
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 03:01:30
            Original ID  :: gnl|Prokka|NAGKNJKB_111
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16247
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16247
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[5226:14211]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5227..14211
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..16247
                     /SMILES="NC([*])C(=O)NC([*])C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16247
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             2..103
                     /locus_tag="ctg111_1"
                     /transl_table=11
                     /translation="MNADMKLIILRKSIMYDKRIAIHWYCENTTEEE"
     CDS             108..944
                     /locus_tag="ctg111_2"
                     /transl_table=11
                     /translation="MLYIGNHTSSSRGYLAMGKQMLANGGNTFAFFTRNPRGGKAKDID
                     PQDVQAFGQLAEENHFGKLVAHAPYTMNCCAAKENLRDFAREIMADDLRRLEMTPGNYY
                     NFHPGSHVGQGAEVGISKIAEILNEVLTKDQSTIVLLETMSGKGTEVGRNFEELRQIID
                     RVELKDKLGVCLDTCHVWDGGYDIVNDLDSVFEEFDRIIGLDRLKAIHLNDSMNPLGSH
                     KDRHARIGEGEIGLEALVRVINHPATEGIPFILETPNDDEGWTHEIALLRNEYKQK"
     CDS             904..1002
                     /locus_tag="ctg111_3"
                     /transl_table=11
                     /translation="MKLRCSEMSINRNEYKYICPNQEDKLGRADKL"
     CDS             1043..1453
                     /locus_tag="ctg111_4"
                     /transl_table=11
                     /translation="MQERSEVQQRQRYQAVEKLRETLDEKYLWEVILLYAGESFKTYTG
                     LPFTYEVRKGRNGDYTRELWIDRRENSKSLALSSVLLALRNIKKVGAVVDRPKALGDIR
                     GVSYIYGMFYRFGLIDVPDTARQKMKFTGYIF"
     CDS             1464..3335
                     /locus_tag="ctg111_5"
                     /transl_table=11
                     /translation="MNKKRNMDSGRKSARPDYIQKTISQKSSGKRSGKVFFPKTLIKTG
                     GIIIFVLLLGFAGNKFFLSVSKTDSGKVKAVSASGADEEKEGRIIEKTKKTKEIKETKD
                     VVEMKKTKEINFQPHCVDSTKPENLISYTNIEVDGNVLENIGDYKADGDISFNIGQDYT
                     DVDGIVTFRGNSFRDTPSHGYADMTDFRLNKLWSADTGSLSSGSAVWTGSGWTGQPLMM
                     KWPKEVKAHMNMTEKATADDELVEVIYACMDGYVYFLDLRTGEKTRDPLYLGYTFKGAG
                     ALDPRGYPIMYVGAGYNSNEGTAKVFVVNLLDCSVMYTFGDNDEFSLRGSLSFFDGSAL
                     VDAETDTLIYPGENGILYLIRLNTKYDLNSGTLSIDPGRTVKWRYYGTRSSTESFWLGM
                     EDSAAIYKGYIFMTDNGGNLMCLDLNTLQLVWVQDTLDDSNSTPVLEIEKGHLYLYVST
                     SFRLGWRSYDTATVPVWKIDAETGEIVWHTDYECTTDDGVSGGVQSTIACGKNSLADYI
                     YVTVAKTSDNASGVLACLRKSDGSKAWEDSSSYAWSSPVCVYNKDGSGKVLYCNSTGDI
                     RLLDGKTGKQEDVLSVSDGVIEASPAAYDNYAVVGTRDCKIWGIRLQ"
     CDS             3468..5213
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 265.3; E-value: 1.5e-80)"
                     /gene_kind="transport"
                     /locus_tag="ctg111_6"
                     /transl_table=11
                     /translation="MEERNNRLLNAKLNKYIVPGIMMSLALQLGNIVDTIFVSNLIGVE
                     AMSAVTLSLPVETIVQLTGYCLGIGGSIAVGNMLGKRDKEGASKLFSATFIVTLVVGII
                     FSICALPAAEPVARLLVSGDGVLTGYTRDYIRVSMLGAPVIGIGLMMVNYLGVENHPEL
                     ASAYLIAANVINLVLDYIFLRYTPLGITGASLSTVLGFLFAMGIFVLYIRSDKRNLHLI
                     LLKPGELGITKEAIITGVPMLIFMAANFVKALGLNTIIMNQLGEEGMAVFTVCDNVLLI
                     VEMLTGGIIGVIPNVAGILFGEKDYVGIRVLCKKMLKYSYILLAVIFVFIMLFTEEITV
                     MFGSGGGELGSHMVQALRIFALCVAPYLWNKFIISYYESIEETAIASFATFLENAVVVL
                     PATLVGILVWKQIDGIGIDGIAAGFVATEIITAVAACIFRKIRHKNTSFYIVPDKNPGI
                     NLDFSIKSTMEEAQTVHKRIIEFCQEQGASKSKANLAAVCAEEMTVNIIRFGGKTSNWI
                     DINLCLEDDLCRLRIRDNGVNFNPLEYQYDSEDFDIHGIELVKKVSKSMDYIRAIDMNN
                     TIISF"
     CDS             5227..14211
                     /NRPS_PKS="Domain: AMP-binding (20-419). E-value: 2.2e-104.
                     Score: 341.1. Matches aSDomain:
                     nrpspksdomains_ctg111_7_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (521-585). E-value: 1.3e-11.
                     Score: 36.8. Matches aSDomain:
                     nrpspksdomains_ctg111_7_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_LCL (597-878). E-value:
                     5.7e-38. Score: 122.5. Matches aSDomain:
                     nrpspksdomains_ctg111_7_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1033-1421). E-value:
                     4.4e-91. Score: 297.3. Matches aSDomain:
                     nrpspksdomains_ctg111_7_AMP-binding.2"
                     /NRPS_PKS="Domain: PP-binding (1530-1591). E-value:
                     1.7e-10. Score: 33.2. Matches aSDomain:
                     nrpspksdomains_ctg111_7_PP-binding.2"
                     /NRPS_PKS="Domain: Condensation_LCL (1603-1879). E-value:
                     3.3e-38. Score: 123.2. Matches aSDomain:
                     nrpspksdomains_ctg111_7_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (2027-2418). E-value:
                     2.9e-94. Score: 307.8. Matches aSDomain:
                     nrpspksdomains_ctg111_7_AMP-binding.3"
                     /NRPS_PKS="Domain: PCP (2523-2590). E-value: 6.8e-21.
                     Score: 66.2. Matches aSDomain:
                     nrpspksdomains_ctg111_7_PCP.1"
                     /NRPS_PKS="Domain: NAD_binding_4 (2634-2872). E-value:
                     1.4e-35. Score: 114.5. Matches aSDomain:
                     nrpspksdomains_ctg111_7_NAD_binding_4.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     141.3; E-value: 8.7e-43)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg111_7"
                     /sec_met_domain="AMP-binding (E-value: 8.8e-109, bitscore:
                     353.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.3e-12, bitscore:
                     36.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 8.1e-49, bitscore:
                     155.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.9e-08,
                     bitscore: 23.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.5e-14, bitscore:
                     41.9, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2.5e-36, bitscore:
                     114.5, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNINERNNFVFEFRPVTELFEEQVKLHPEKCAVVSGKESFTYAQ
                     LNERANRIANALVEKGVRRETIVGVVLERCCDFYAVRQGILKTGGAFAVATPDYPDDRI
                     RYIFEDSGAPFIITTKEIAEERRELFAKLPCTVLLIEELLENENTENPQVKIGEHDLCY
                     CIYTSGSTGKPKGVLIEHINLANFVNPDSKNAETYGYVSRGSVSLSMAAMTFDVSVLEE
                     FLPLTNGMTAVIASDEEILNPLMLGELIVRNKVDIMTTTPTYLSNMIDLPQLEKAVSQI
                     KVFDVGAEAFPPALYDKIRRVNPDAYIMNGYGPTETTISCTMKVITDSRNITIGTPNGN
                     VKVYIVDKENKILPDGETGELVIAGLGVGRGYMNLPDKTEAVFIDLNGERAYKTGDLAR
                     ISPEGEIEFFGRIDNQIKLRGLRIELGEIEEVINSYEGIITSITLPVDNKFLCCYFMAD
                     RQINTEELSVYASESLAHYMVPEVFVQLEKMPVTQNGKIDKKALPKPVAQPKNLKEPQT
                     PMQKKIFEIVADVVENDFFGTDTSFYRAGLSSISAMKLCILISEEFGVTVKTSDIHENN
                     TVEKLEKYVMLAPKIRTYEKREVYPLTGSQKGIFAECMKNPESTVYNIPFLFELESSVD
                     VQKLSDAISQMIAAHPYLLTKVYLSDSGEMVQKPCEEAFVPEVVRTTNEQFEKMKDELV
                     RPFKLEKGRLFRAGIYVTEDRKYLFTDFHHILADGNSYDIIFEDIDRAYLGEKLEKESY
                     TGFDAALDEEQQMKEGKYKKAEKYYDSIFEGIETESLPLPDCSGKTPERGYLSVPVDTR
                     ESLVLSACEKLGVTPNILFTGVFGILMSRYSNSEESLFATIYNGRNDSRLENTVCMLVK
                     TLPVYCSCDPKVTIQAYMTELSEQILSSMANDIFPFSDICAKYGINSDLVFAYQAELGD
                     DFPIGDTVARGHDLSPDMSKMPLLIQVREYDHKYVLTAEYRSDMYSEAFVRGMLESYEA
                     AMDSLLKAKYISEVSVLSQNGADKISEFNNTACEYDRSKTIADMFEELVQTIPDHTAVV
                     FKDKKYTYRELDEISDRLGKYIASQGIGSEDVVSILIPRCEYMAIAPMGVIKAGAAYQP
                     LDPTYPRDRLMYMMEDSSAKLLIVDRELLPLVDGYKGPVLFTDQIWQLEDRDVVLKKPQ
                     LHDLFILLYTSGSTGVPKGCMLEYGNITAFCHWFKRYYGIDSESRIAAYASFGFDACMM
                     DIYGAITNGAQLHIIPEEIRLDFIGLQRYFEENGITHSFMTTQVGRQFALEMDCKSLRY
                     LSVGGEKLVPCEPPKDYKFINAYGPTEATIFTTVFEVDKYYPNVPIGKALDNVKLYITD
                     KLGHMLPPGACGELMITGWQVSRGYLNKPEKTAEVYTKNLYDDTPGYEVMYHSGDVARF
                     LPDGNIQIIGRKDSQVKIRGFRIELSEVEEVIRRYEGIRDATVVAFDDPNGGKYIAAYV
                     VSDSTVDINALNDFIKETKPAYMVPAVTMQIDKIPLNQNQKVNKKALPLPEKKAAEIIK
                     PENEVQQILFDCIAEVLGYTDFGITTDIYEAGLTSITAIKLNILISKAFDIVIKTSDIK
                     NHPTIRMMEEFVKTAGKESKREVQESYPLTNTQEGIFIECTANMGSTIYNIPYLLKLDN
                     KVDLDRLAEAIDSTVEAHPYLKTRLFMDDNGNVLQKRNDGLSYKTPILNGMNRDTLVRP
                     YMLFNEQLFRFEIYRTCDGNYLFLDLHHIVADGTSLAIIINDINRAYSGEKLEPEGYTS
                     YDLALDNRDALAGDIYKNAENYYKSVFEHAGGSISFYPDKNGAAPTAELYHRETRSISV
                     QDVKEFCKKHGITENVFFISAFGITLGKYNFKKDAVFTTIYHGRNDSRLSETVGMLVKT
                     LPVFCDFSGTAKDCLSGVQKQLIDSMNNDIYPFSQISHEFDIKADAMVIYQGDNFAFDT
                     IGGEYAQEEPVSLNMAKAPVSVSISIEKNRFVFEIEYRGDMYHEETIRYLTDNLETTAE
                     GILRECDPADIRLMFEEETQMEDIPEHAGKTFIDLFKEMAARYPDRPAVRDDSGDFTYR
                     ELDRMSDYIAQKLTENGFGPEQAAGILCGRTKEYTVAYVGVMKAGGAYVPLDPEYPQSR
                     IEYMLKDSGARNLLVIDQYQNLVEFYDGNVISLDSVSDEAEDFELSAELISPKPENLAY
                     MIYTSGSTGKPKGVMIEHRNLLNLIEYITLSRNTSPDDIVAEFASFCFDASVIDLFAPL
                     TAGAVLYILPESIRKDAIAISRYIKEKEITTVTFPTQMGELVTELLEDAPALKFVTLGG
                     EKFKHYRNRTYQMINGYGPTENTVSSTEFLVDRQYDNIPIGKSQRNVRSYIVDENLNRL
                     PVGASGELCHAGRQIARGYHNLPEKTASVFVENPFAVCEQESRLYRTGDMVRMKGDGNI
                     EYIGRIDSQVKIRGYRVELGEIEGALLKHELVKNAAVTVIEKGGNKYITAYYTGEAIPE
                     DELKTFLEPLIPDYMMPSFFVSIEEMPVTPGGKIDKKALPMPEVTTNTASYVEPVTAAQ
                     RALCEIFEKALGIERVGIEDNFFELGGSSLTASKVAVMCLSKNISLVYADIFKYPTVRE
                     LAALVDDDGVTEAAQSKNEFSDYNYNRIQNVISANTEENADRITKEKLGDIMVTGATGF
                     LGIHVLKAFLDNYDGKVYCLVRKGKYESPEKRMMNMLMYYFDDPYKELFESRIICVDGD
                     ITSKEQVTGFSEYKFSTIINCAACVKHFAADDVLERINVQGVENLIDFCKNNGRRLIQI
                     STVSVAGEGSDGVPPMSRVFCENDLYIGQNITNEYIRTKFLAERAVLEAVSEGLDGKVV
                     RVGNLMSRNSDGEFQINFITNGFLRSLRGYAAVGKFPMGGMHEVAEFSPIDSTALAVLR
                     LAQTDRRFTVFHACNSHHIYMADLIYAMRSYGFRIDIVRDEEFEAAVKEFAKTGQDSDA
                     VSGLIAYTSHNENEIYTIDYSNRFTAQVLYRLDYKWPVTDDRYLENAIAALDRLTFFD"
     aSDomain        5287..6483
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg111_7_AMP-binding.1"
                     /evalue="2.20E-104"
                     /label="ctg111_7_AMP-binding.1"
                     /locus_tag="ctg111_7"
                     /protein_end="419"
                     /protein_start="20"
                     /score="341.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEEQVKLHPEKCAVVSGKESFTYAQLNERANRIANALVEKGVRRE
                     TIVGVVLERCCDFYAVRQGILKTGGAFAVATPDYPDDRIRYIFEDSGAPFIITTKEIAE
                     ERRELFAKLPCTVLLIEELLENENTENPQVKIGEHDLCYCIYTSGSTGKPKGVLIEHIN
                     LANFVNPDSKNAETYGYVSRGSVSLSMAAMTFDVSVLEEFLPLTNGMTAVIASDEEILN
                     PLMLGELIVRNKVDIMTTTPTYLSNMIDLPQLEKAVSQIKVFDVGAEAFPPALYDKIRR
                     VNPDAYIMNGYGPTETTISCTMKVITDSRNITIGTPNGNVKVYIVDKENKILPDGETGE
                     LVIAGLGVGRGYMNLPDKTEAVFIDLNGERAYKTGDLARISPEGEIEFFGRIDNQIKLR
                     "
     aSModule        5287..6981
                     /complete
                     /domains="nrpspksdomains_ctg111_7_AMP-binding.1"
                     /domains="nrpspksdomains_ctg111_7_PP-binding.1"
                     /locus_tags="ctg111_7"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       5476..5502
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0001"
                     /evalue="4.20E+00"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg111_7"
                     /protein_end="92"
                     /protein_start="83"
                     /score="1.8"
                     /tool="antismash"
                     /translation="GILKTGGAF"
     CDS_motif       5710..5769
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0002"
                     /evalue="1.70E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg111_7"
                     /protein_end="181"
                     /protein_start="161"
                     /score="29.7"
                     /tool="antismash"
                     /translation="CYCIYTSGSTGKPKGVLIEH"
     CDS_motif       6160..6189
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0003"
                     /evalue="3.10E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg111_7"
                     /protein_end="321"
                     /protein_start="311"
                     /score="7.4"
                     /tool="antismash"
                     /translation="YGPTETTISC"
     CDS_motif       6286..6375
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0004"
                     /evalue="2.90E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg111_7"
                     /protein_end="383"
                     /protein_start="353"
                     /score="35.6"
                     /tool="antismash"
                     /translation="PDGETGELVIAGLGVGRGYMNLPDKTEAVF"
     CDS_motif       6448..6513
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0005"
                     /evalue="5.90E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg111_7"
                     /protein_end="429"
                     /protein_start="407"
                     /score="31.3"
                     /tool="antismash"
                     /translation="FFGRIDNQIKLRGLRIELGEIE"
     aSDomain        6790..6981
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg111_7_PP-binding.1"
                     /evalue="1.30E-11"
                     /label="ctg111_7_PP-binding.1"
                     /locus_tag="ctg111_7"
                     /protein_end="585"
                     /protein_start="521"
                     /score="36.8"
                     /tool="antismash"
                     /translation="KIFEIVADVVENDFFGTDTSFYRAGLSSISAMKLCILISEEFGVT
                     VKTSDIHENNTVEKLEKYV"
     aSDomain        7018..7860
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg111_7_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.70E-38"
                     /label="ctg111_7_Condensation_LCL.1"
                     /locus_tag="ctg111_7"
                     /protein_end="878"
                     /protein_start="597"
                     /score="122.5"
                     /tool="antismash"
                     /translation="EVYPLTGSQKGIFAECMKNPESTVYNIPFLFELESSVDVQKLSDA
                     ISQMIAAHPYLLTKVYLSDSGEMVQKPCEEAFVPEVVRTTNEQFEKMKDELVRPFKLEK
                     GRLFRAGIYVTEDRKYLFTDFHHILADGNSYDIIFEDIDRAYLGEKLEKESYTGFDAAL
                     DEEQQMKEGKYKKAEKYYDSIFEGIETESLPLPDCSGKTPERGYLSVPVDTRESLVLSA
                     CEKLGVTPNILFTGVFGILMSRYSNSEESLFATIYNGRNDSRLENTVCMLVKTLPVYCS
                     "
     aSModule        7018..9999
                     /complete
                     /domains="nrpspksdomains_ctg111_7_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg111_7_AMP-binding.2"
                     /domains="nrpspksdomains_ctg111_7_PP-binding.2"
                     /locus_tags="ctg111_7"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       7084..7179
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0006"
                     /evalue="9.10E-06"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg111_7"
                     /protein_end="651"
                     /protein_start="619"
                     /score="18.1"
                     /tool="antismash"
                     /translation="TVYNIPFLFELESSVDVQKLSDAISQMIAAHP"
     CDS_motif       7390..7455
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0007"
                     /evalue="3.10E-04"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg111_7"
                     /protein_end="743"
                     /protein_start="721"
                     /score="13.5"
                     /tool="antismash"
                     /translation="FHHILADGNSYDIIFEDIDRAY"
     CDS_motif       7792..7851
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0008"
                     /evalue="5.10E-01"
                     /label="C5_starter_265-294"
                     /locus_tag="ctg111_7"
                     /protein_end="875"
                     /protein_start="855"
                     /score="3.1"
                     /tool="antismash"
                     /translation="GRNDSRLENTVCMLVKTLPV"
     aSDomain        8326..9489
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg111_7_AMP-binding.2"
                     /evalue="4.40E-91"
                     /label="ctg111_7_AMP-binding.2"
                     /locus_tag="ctg111_7"
                     /protein_end="1421"
                     /protein_start="1033"
                     /score="297.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEELVQTIPDHTAVVFKDKKYTYRELDEISDRLGKYIASQGIGSE
                     DVVSILIPRCEYMAIAPMGVIKAGAAYQPLDPTYPRDRLMYMMEDSSAKLLIVDRELLP
                     LVDGYKGPVLFTDQIWQLEDRDVVLKKPQLHDLFILLYTSGSTGVPKGCMLEYGNITAF
                     CHWFKRYYGIDSESRIAAYASFGFDACMMDIYGAITNGAQLHIIPEEIRLDFIGLQRYF
                     EENGITHSFMTTQVGRQFALEMDCKSLRYLSVGGEKLVPCEPPKDYKFINAYGPTEATI
                     FTTVFEVDKYYPNVPIGKALDNVKLYITDKLGHMLPPGACGELMITGWQVSRGYLNKPE
                     KTAEVYTKNLYDDTPGYEVMYHSGDVARFLPDGNIQIIGRKDSQVKIR"
     CDS_motif       8512..8553
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0009"
                     /evalue="5.90E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg111_7"
                     /protein_end="1109"
                     /protein_start="1095"
                     /score="13.3"
                     /tool="antismash"
                     /translation="MGVIKAGAAYQPLD"
     CDS_motif       8743..8793
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0010"
                     /evalue="1.40E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg111_7"
                     /protein_end="1189"
                     /protein_start="1172"
                     /score="20.8"
                     /tool="antismash"
                     /translation="LLYTSGSTGVPKGCMLE"
     CDS_motif       9145..9171
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0011"
                     /evalue="8.40E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg111_7"
                     /protein_end="1315"
                     /protein_start="1306"
                     /score="6.2"
                     /tool="antismash"
                     /translation="YGPTEATIF"
     CDS_motif       9274..9360
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0012"
                     /evalue="2.10E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg111_7"
                     /protein_end="1378"
                     /protein_start="1349"
                     /score="39.2"
                     /tool="antismash"
                     /translation="PPGACGELMITGWQVSRGYLNKPEKTAEV"
     CDS_motif       9457..9519
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0013"
                     /evalue="1.60E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg111_7"
                     /protein_end="1431"
                     /protein_start="1410"
                     /score="33.1"
                     /tool="antismash"
                     /translation="IGRKDSQVKIRGFRIELSEVE"
     aSDomain        9817..9999
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg111_7_PP-binding.2"
                     /evalue="1.70E-10"
                     /label="ctg111_7_PP-binding.2"
                     /locus_tag="ctg111_7"
                     /protein_end="1591"
                     /protein_start="1530"
                     /score="33.2"
                     /tool="antismash"
                     /translation="DCIAEVLGYTDFGITTDIYEAGLTSITAIKLNILISKAFDIVIKT
                     SDIKNHPTIRMMEEFV"
     aSDomain        10036..10863
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg111_7_Condensation_LCL.2"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.30E-38"
                     /label="ctg111_7_Condensation_LCL.2"
                     /locus_tag="ctg111_7"
                     /protein_end="1879"
                     /protein_start="1603"
                     /score="123.2"
                     /tool="antismash"
                     /translation="ESYPLTNTQEGIFIECTANMGSTIYNIPYLLKLDNKVDLDRLAEA
                     IDSTVEAHPYLKTRLFMDDNGNVLQKRNDGLSYKTPILNGMNRDTLVRPYMLFNEQLFR
                     FEIYRTCDGNYLFLDLHHIVADGTSLAIIINDINRAYSGEKLEPEGYTSYDLALDNRDA
                     LAGDIYKNAENYYKSVFEHAGGSISFYPDKNGAAPTAELYHRETRSISVQDVKEFCKKH
                     GITENVFFISAFGITLGKYNFKKDAVFTTIYHGRNDSRLSETVGMLVKTLPVFC"
     aSModule        10036..13842
                     /complete
                     /domains="nrpspksdomains_ctg111_7_Condensation_LCL.2"
                     /domains="nrpspksdomains_ctg111_7_AMP-binding.3"
                     /domains="nrpspksdomains_ctg111_7_PCP.1"
                     /domains="nrpspksdomains_ctg111_7_NAD_binding_4.1"
                     /locus_tags="ctg111_7"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       10102..10212
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0014"
                     /evalue="2.50E-07"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg111_7"
                     /protein_end="1662"
                     /protein_start="1625"
                     /score="23.1"
                     /tool="antismash"
                     /translation="TIYNIPYLLKLDNKVDLDRLAEAIDSTVEAHPYLKTR"
     CDS_motif       10393..10458
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0015"
                     /evalue="1.60E-07"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg111_7"
                     /protein_end="1744"
                     /protein_start="1722"
                     /score="23.9"
                     /tool="antismash"
                     /translation="LHHIVADGTSLAIIINDINRAY"
     CDS_motif       10777..10857
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0016"
                     /evalue="3.60E-02"
                     /label="C5_starter_265-294"
                     /locus_tag="ctg111_7"
                     /protein_end="1877"
                     /protein_start="1850"
                     /score="6.8"
                     /tool="antismash"
                     /translation="VFTTIYHGRNDSRLSETVGMLVKTLPV"
     aSDomain        11308..12480
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg111_7_AMP-binding.3"
                     /evalue="2.90E-94"
                     /label="ctg111_7_AMP-binding.3"
                     /locus_tag="ctg111_7"
                     /protein_end="2418"
                     /protein_start="2027"
                     /score="307.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FKEMAARYPDRPAVRDDSGDFTYRELDRMSDYIAQKLTENGFGPE
                     QAAGILCGRTKEYTVAYVGVMKAGGAYVPLDPEYPQSRIEYMLKDSGARNLLVIDQYQN
                     LVEFYDGNVISLDSVSDEAEDFELSAELISPKPENLAYMIYTSGSTGKPKGVMIEHRNL
                     LNLIEYITLSRNTSPDDIVAEFASFCFDASVIDLFAPLTAGAVLYILPESIRKDAIAIS
                     RYIKEKEITTVTFPTQMGELVTELLEDAPALKFVTLGGEKFKHYRNRTYQMINGYGPTE
                     NTVSSTEFLVDRQYDNIPIGKSQRNVRSYIVDENLNRLPVGASGELCHAGRQIARGYHN
                     LPEKTASVFVENPFAVCEQESRLYRTGDMVRMKGDGNIEYIGRIDSQVKIR"
     CDS_motif       11497..11535
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0017"
                     /evalue="3.30E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg111_7"
                     /protein_end="2103"
                     /protein_start="2090"
                     /score="17.1"
                     /tool="antismash"
                     /translation="GVMKAGGAYVPLD"
     CDS_motif       11728..11787
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0018"
                     /evalue="8.00E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg111_7"
                     /protein_end="2187"
                     /protein_start="2167"
                     /score="33.7"
                     /tool="antismash"
                     /translation="AYMIYTSGSTGKPKGVMIEH"
     CDS_motif       12136..12165
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0019"
                     /evalue="9.60E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg111_7"
                     /protein_end="2313"
                     /protein_start="2303"
                     /score="6.0"
                     /tool="antismash"
                     /translation="YGPTENTVSS"
     CDS_motif       12265..12354
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0020"
                     /evalue="1.90E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg111_7"
                     /protein_end="2376"
                     /protein_start="2346"
                     /score="39.3"
                     /tool="antismash"
                     /translation="PVGASGELCHAGRQIARGYHNLPEKTASVF"
     CDS_motif       12445..12510
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg111_7_0021"
                     /evalue="1.00E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg111_7"
                     /protein_end="2428"
                     /protein_start="2406"
                     /score="36.7"
                     /tool="antismash"
                     /translation="YIGRIDSQVKIRGYRVELGEIE"
     aSDomain        12796..12996
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg111_7_PCP.1"
                     /evalue="6.80E-21"
                     /label="ctg111_7_PCP.1"
                     /locus_tag="ctg111_7"
                     /protein_end="2590"
                     /protein_start="2523"
                     /score="66.2"
                     /tool="antismash"
                     /translation="RALCEIFEKALGIERVGIEDNFFELGGSSLTASKVAVMCLSKNIS
                     LVYADIFKYPTVRELAALVDDD"
     aSDomain        13129..13842
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg111_7_NAD_binding_4.1"
                     /evalue="1.40E-35"
                     /label="ctg111_7_NAD_binding_4.1"
                     /locus_tag="ctg111_7"
                     /protein_end="2872"
                     /protein_start="2634"
                     /score="114.5"
                     /tool="antismash"
                     /translation="VTGATGFLGIHVLKAFLDNYDGKVYCLVRKGKYESPEKRMMNMLM
                     YYFDDPYKELFESRIICVDGDITSKEQVTGFSEYKFSTIINCAACVKHFAADDVLERIN
                     VQGVENLIDFCKNNGRRLIQISTVSVAGEGSDGVPPMSRVFCENDLYIGQNITNEYIRT
                     KFLAERAVLEAVSEGLDGKVVRVGNLMSRNSDGEFQINFITNGFLRSLRGYAAVGKFPM
                     GGMHEVAEFSPIDSTA"
     CDS             14231..14533
                     /locus_tag="ctg111_8"
                     /transl_table=11
                     /translation="MEIITKTEGNKATMEISGWLDTQTAPQLGEALSGLEDSITSLVFD
                     FTNLEYISSAGLRQVIVAYKKMAQKDGFKIINVSDEVYDVFSLTGFDSKIDIQKK"
     CDS             14545..15192
                     /NRPS_PKS="Domain: ACPS (98-159). E-value: 2.8e-13. Score:
                     41.7. Matches aSDomain: nrpspksdomains_ctg111_9_ACPS.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012:4'-phosphopantetheinyl transferase (Score: 129.3;
                     E-value: 2.1e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg111_9"
                     /transl_table=11
                     /translation="MQKLYRININHFEDPLKNERLLDLVGIRRREKVIRYRMPDDRKRS
                     LGAGIIIRKILDENGLTESCLRYSDNEKPVVDGLFFNVSHAGDYVVGVLSDCEVGCDIE
                     KNANAPLEVAEHYFYHSELAYIKAAKNKDKAFFTLWTLKESYMKMTGRGMSLPLDSFEV
                     VPTEEGFVLGKSSERPCFFETMEFDGYIFSVSSERAFSLHNPLKIVFDDIYV"
     aSDomain        14839..15021
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg111_9_ACPS.1"
                     /evalue="2.80E-13"
                     /label="ctg111_9_ACPS.1"
                     /locus_tag="ctg111_9"
                     /protein_end="159"
                     /protein_start="98"
                     /score="41.7"
                     /tool="antismash"
                     /translation="VGCDIEKNANAPLEVAEHYFYHSELAYIKAAKNKDKAFFTLWTLK
                     ESYMKMTGRGMSLPLD"
     CDS             complement(15207..16247)
                     /locus_tag="ctg111_10"
                     /transl_table=11
                     /translation="MKIINMIVKKMPILQGFPDFETVNFFTGKLFQKYNFTPVFYDIET
                     TGLSRNSTYLYLIGAVGIEDETWYFYQWMAENASEEETILRIFSQFLQQYNLMISYNGE
                     RFDQPYLEARYEKYGIPSPFTGKQSLDLYLTLKPLKSLLKLPAMKQPCMEEFLGIKDRI
                     YDNGKECIKLYKDFLKKRETFTAEEILGHNLEDVLGLGRIFDMLGYLCVYDGDYEVTYS
                     EFDGDNLILKLKLPCTLPQEFSNGNTDFYLTGKDEEINLIIKTTDGKLKQYYADYKDYY
                     YLPEEDTVIPKSLGSGIDRKHRKAATRNTCYTWFTCSDAFLSSPVQQKQYLTYTLSCLI
                     GTLECV"
ORIGIN
        1 ctataatgca gatatgaaac tgataatctt gagaaaatcc ataatgtatg ataaaaggat
       61 tgctatacac tggtactgtg aaaatacgac agaagaggag taaaaaaatg ttatatatag
      121 gaaatcacac aagctcatcc cggggatatc ttgcaatggg gaagcagatg ctggcaaatg
      181 gcggtaacac atttgcattt tttaccagaa atccaagagg agggaaagcc aaagacattg
      241 atccgcagga tgtgcaggca tttgggcagc tggcagaaga gaatcatttt ggaaagctgg
      301 tggctcatgc gccttacact atgaactgct gcgctgccaa agaaaacctc agggattttg
      361 ccagagaaat catggcagat gatctgagac gtctggaaat gacaccggga aattattaca
      421 attttcatcc gggcagtcac gtaggacagg gtgcagaagt aggaatcagt aaaattgcag
      481 aaattctcaa tgaagtgctg acaaaagatc agagtacgat tgtacttctg gaaactatgt
      541 caggaaaggg cacagaagta ggaagaaatt tcgaagaact tcgtcagatc attgacaggg
      601 tggagttaaa agataaatta ggtgtttgcc tggatacctg tcatgtctgg gatggtggat
      661 atgatattgt aaacgatctt gacagcgtat ttgaggaatt tgaccggata ataggtctgg
      721 acagactaaa agccatccat ttaaatgaca gcatgaatcc ccttggcagc cataaggacc
      781 gccatgccag aatcggagaa ggtgaaatag gactggaggc acttgtccgc gtgatcaatc
      841 atcctgccac agagggaatt ccgtttattc tggagacacc aaatgatgat gagggatgga
      901 ctcatgaaat tgcgttgctc agaaatgagt ataaacagaa atgagtataa atatatctgt
      961 ccgaatcagg aagataaatt ggggcgtgct gacaagttgt aagtgcaaat caaaagagca
     1021 ggagtgagat caaaaggaag gaatgcagga aagatcagag gtgcagcaaa gacaaagata
     1081 tcaggcagta gagaagctga gagaaacact ggacgagaag tatctgtggg aggttatttt
     1141 actctatgca ggtgagagtt tcaaaaccta tacagggctt ccgttcactt atgaagtaag
     1201 aaagggtcgg aatggagact acacaaggga attgtggatc gaccgtaggg agaacagtaa
     1261 gagtctggcg ttaagttcag tgctgctggc attgagaaac ataaagaagg tgggagctgt
     1321 ggttgacaga cccaaagctc tgggcgacat ccgcggagtg agttatatct atggaatgtt
     1381 ctaccgcttt gggctgatcg atgtgccgga tacagccagg cagaagatga agttcacagg
     1441 atatattttt taggaggaaa ggtatgaaca agaagagaaa catggattct gggagaaaat
     1501 ctgcaagacc ggattacatt cagaaaacaa tatcacagaa aagttcagga aaacgcagtg
     1561 gaaaagtttt cttccccaaa accctcataa agactggggg gattataatt tttgtacttc
     1621 tgcttgggtt tgcaggaaac aagtttttcc tgtctgtcag caaaacagac agcgggaagg
     1681 tgaaggccgt atcagcttca ggtgcagatg aggaaaaaga aggcaggata atcgaaaaaa
     1741 ctaaaaaaac taaagaaatt aaagaaacca aagatgtggt tgaaatgaaa aagactaaag
     1801 agattaattt tcagcctcat tgtgtggatt ctacaaaacc ggaaaatctg atcagctata
     1861 ctaatattga ggtggatgga aacgtacttg aaaatattgg agattataag gctgatggtg
     1921 atatttcctt taatatagga caggattata cagatgtgga tggaatcgtc acatttcgcg
     1981 gaaacagttt tcgcgataca ccttcccatg gttatgcaga tatgactgat ttcaggctga
     2041 acaaactgtg gtctgcagat acaggttctc tttcttcggg cagtgcagtc tggacaggaa
     2101 gtggctggac aggacagccg cttatgatga aatggccaaa agaggtcaaa gcacatatga
     2161 atatgacaga gaaagcaacg gcagatgatg agctggttga ggtgatttat gcctgtatgg
     2221 atgggtatgt gtattttctg gatctgagaa cgggagaaaa gacacgtgac ccattatatc
     2281 tgggatatac ttttaagggt gcgggtgccc ttgatccgag aggatatccg attatgtatg
     2341 ttggcgccgg atataacagc aacgaaggaa ctgcaaaggt atttgtagta aacttgctgg
     2401 attgtagtgt tatgtatact tttggagaca atgatgagtt ttcactcaga ggaagtctga
     2461 gcttttttga cggatcagca cttgtggatg cagagacaga taccctgatc tatccgggag
     2521 agaacggaat cctgtatctg atcaggctga atacaaaata tgatctgaac agtgggactt
     2581 tatccattga tccgggcaga actgtaaaat ggcgctacta tggaacaaga agcagtacag
     2641 agtctttctg gcttggaatg gaagacagtg cggcaatcta taaaggctat atatttatga
     2701 ccgataatgg gggaaatctt atgtgtctgg acctgaacac tcttcagctg gtatgggttc
     2761 aggatacatt ggatgattct aattcaacgc ctgttctgga aatcgaaaaa ggacatctgt
     2821 atctgtatgt aagtacttcc ttccgccttg gatggagaag ttatgacaca gccactgtcc
     2881 ctgtctggaa gattgatgca gaaaccggcg agatcgtgtg gcatacagat tatgaatgta
     2941 ctactgatga cggtgtttcc ggtggagttc agtctacgat tgcttgtgga aagaacagcc
     3001 ttgccgatta tatatatgtg acagtggcaa agacctctga caatgcatcg ggagttcttg
     3061 cctgtctgag aaaatctgac ggatctaaag catgggagga ttcttcctca tatgcctggt
     3121 cttctccggt gtgcgtttat aacaaagacg gatcaggaaa ggttctttat tgcaacagta
     3181 caggcgatat ccgccttctt gatggtaaaa caggtaaaca ggaagatgta ttatctgtca
     3241 gcgatggcgt gatagaggct tccccggctg cctacgataa ctatgcggtt gtaggcacca
     3301 gagactgtaa aatatgggga atcaggttac agtaaatagc aatatttatt tgctttctcc
     3361 cattctttat taacttgcca tttatcgcac taaatggtaa aatttaaata tcttacagtt
     3421 ttacggcaca atattttgaa aaaactgaaa acaaaggaga ggaagcgatg gaagagagaa
     3481 ataacagact gctgaatgcg aagctgaaca agtatattgt tccggggatt atgatgtctc
     3541 tggcgcttca gctgggaaat atcgtagata cgatatttgt aagtaacctg atcggggtgg
     3601 aggcaatgtc tgcagttacc ctgagcctgc ctgtggagac aatcgttcag ctgacaggat
     3661 actgccttgg tatcggcggt tccatagcag tgggaaacat gcttggcaaa cgagacaaag
     3721 aaggggcatc gaaattgttt tctgccacat ttatagtaac acttgtggtg ggaatcattt
     3781 tttcaatctg cgcccttcct gcagcagaac ctgttgccag acttctggta tcaggtgacg
     3841 gtgtcctgac cggttatacc agagattaca tacgtgtaag tatgctgggg gcaccggtga
     3901 tcggaattgg actgatgatg gtcaattacc ttggtgtgga gaatcatccg gagctggcat
     3961 cagcctacct tatcgcagcc aatgtgatca atcttgtgct ggactatata ttcctcagat
     4021 atactccgct gggaattaca ggtgcatcct tatcaactgt tcttggtttc ctgtttgcaa
     4081 tgggaatttt tgtgctttat atccgctctg ataagcgaaa cctccacctg atcctgctaa
     4141 agccgggcga acttggaatc acaaaggaag caatcatcac aggcgtgcca atgctgatct
     4201 ttatggcagc taattttgta aaggcgcttg gactgaatac cattatcatg aaccagctgg
     4261 gcgaggaagg tatggcagta tttactgtct gtgacaatgt gctgctgatc gtcgagatgc
     4321 ttacaggcgg aatcatcggt gtgatcccca atgtggcagg aatccttttt ggagagaagg
     4381 actacgtggg aatccgggtt ctctgtaaaa agatgctgaa atacagttac atcctgctgg
     4441 ctgtgatctt tgtctttatt atgctgttta ccgaggaaat cactgtcatg ttcggaagcg
     4501 gcggtggcga gctgggcagt catatggtcc aggcgctgcg catctttgct ttgtgtgtgg
     4561 caccttatct gtggaataag tttattatca gctattacga gtccattgag gagacagcca
     4621 ttgcaagttt tgccacattt ctggagaatg cggtggtagt tctgcctgca accctggtgg
     4681 gaatccttgt atggaaacag attgacggga ttggtatcga cggaattgca gcaggatttg
     4741 ttgccactga gatcataact gcagttgcag cctgtatttt cagaaaaatc aggcataaga
     4801 atacaagctt ttatattgtt cctgacaaaa atccggggat taatctggat ttttccatta
     4861 agagtaccat ggaggaagca caaacggttc ataagaggat catagagttc tgccaggaac
     4921 agggagcttc taaaagcaag gcaaatcttg ccgcagtgtg tgcggaggaa atgactgtaa
     4981 atattatacg attcggtgga aaaacctcca actggatcga cattaacctc tgtctggagg
     5041 atgatctctg cagactgagg atcagagata acggtgtaaa tttcaaccct ctggaatatc
     5101 agtatgacag tgaagacttt gatatacatg ggattgaact tgtcaagaag gtatcaaaat
     5161 ccatggatta tattcgtgcg attgatatga ataataccat aatatctttt taggaggtac
     5221 atgaaaatga aaaatattaa tgaaaggaac aattttgttt ttgagtttcg gccggtaaca
     5281 gaattgttcg aggaacaggt gaagcttcat cctgagaaat gtgcagttgt ctccggcaaa
     5341 gagagcttta cctatgcaca gctcaatgaa cgggccaaca ggattgccaa tgcacttgtg
     5401 gaaaaaggtg tcagacggga gaccatcgta ggtgtggttc ttgagagatg ctgtgatttc
     5461 tatgcagtgc gacagggtat cctgaagaca ggaggcgcat ttgcagttgc cacaccggat
     5521 tatcctgatg acaggatccg atatattttt gaggattcag gagctccttt tattatcaca
     5581 acaaaggaga tcgcagagga acgaagggaa ctgtttgcta agcttccctg tacagtactt
     5641 ctgatcgagg aacttctgga gaatgagaat acagagaatc ctcaggtaaa gatcggggag
     5701 catgatcttt gttattgtat ctatacttct ggttccacag gcaagcccaa gggtgtgctg
     5761 atcgaacata tcaaccttgc caattttgta aatccggatt cgaaaaatgc ggaaacttat
     5821 ggttatgtaa gcagaggaag tgtatctctt tccatggcag ccatgacctt tgatgtgtct
     5881 gttctggagg aatttctgcc acttaccaac gggatgactg cggtgatcgc ctctgatgag
     5941 gagattttga atcctcttat gctgggtgag ctgatcgtca gaaataaagt ggatattatg
     6001 accacaactc ctacttacct gtccaatatg atcgatctgc cccagcttga aaaagcagtt
     6061 tctcagatta aggtgtttga tgtaggtgca gaggcttttc ctccggctct gtatgacaag
     6121 attcgcagag taaacccgga tgcttacatt atgaatggtt atggacctac ggaaactacc
     6181 atcagctgta ccatgaaggt aattacggac agcagaaaca ttaccattgg tacgcctaac
     6241 ggtaatgtga aggtatatat tgtagataaa gagaataaga tccttccgga cggagagacc
     6301 ggagagcttg tgattgcagg actgggcgtt ggcagaggtt atatgaatct gccggataaa
     6361 acagaggctg tattcattga tcttaacgga gagagagctt ataagaccgg tgaccttgca
     6421 aggatcagcc ctgagggtga gattgaattt ttcggaagaa tagacaatca gatcaagctt
     6481 cgcggtctga ggattgagct tggtgagatc gaggaggtga tcaattccta tgagggaatc
     6541 attaccagca ttactctgcc tgtagataac aaattcctct gctgctattt tatggctgac
     6601 cgccagatca atacagagga gctttctgtc tatgcatcag agtccctggc tcattatatg
     6661 gttcctgagg tttttgtcca actggaaaag atgcctgtga cacagaatgg taaaattgat
     6721 aagaaagcac tgccaaagcc ggttgcacag ccaaagaatc tgaaagaacc ccagactcct
     6781 atgcagaaga agatttttga aatcgttgca gacgttgtgg agaatgattt ttttggaact
     6841 gacacaagtt tttacagggc ggggctgtct tctatcagtg ccatgaagct ttgtattctg
     6901 atctcagagg aattcggagt gactgtgaaa accagtgata tccacgaaaa caatacggtg
     6961 gagaagctgg aaaaatatgt gatgcttgca ccgaagatca gaacctatga aaagagagaa
     7021 gtttaccctc ttaccggctc ccagaagggt atttttgcag agtgcatgaa gaatcctgag
     7081 agtacggtat acaatattcc gttcctgttt gaactggaaa gctctgttga cgttcagaag
     7141 ctgtcagatg ccatttctca gatgatcgct gcacatccgt atctgctgac aaaggtttat
     7201 ttaagtgaca gcggagagat ggtgcagaag ccttgtgagg aagcctttgt accagaggtg
     7261 gtccggacca caaatgagca gtttgaaaag atgaaagatg agctggtgcg tccctttaag
     7321 ctggaaaagg gacggctgtt ccgggcgggg atttatgtga cagaagacag gaaatatctt
     7381 tttacagatt tccaccatat cctggcagat ggtaattcct atgatattat ttttgaggat
     7441 atcgatcggg cctatctggg tgagaaattg gagaaagaat cctacacagg ctttgatgct
     7501 gcccttgatg aagaacagca gatgaaagag ggaaaatata agaaggccga gaaatattat
     7561 gacagtattt tcgagggaat tgagacagaa tccctgcctc ttcctgactg ttcaggaaag
     7621 actcctgaga gaggatatct gtcggtgcct gtggacacca gagagtctct ggtactttct
     7681 gcctgcgaga agctgggggt tactccaaac attctgttta caggtgtatt cggcattctc
     7741 atgagcagat attccaattc cgaggagagt ctttttgcaa ctatttataa tggaagaaat
     7801 gattccagac tggagaatac agtctgcatg cttgtaaaga ctctgccggt ttactgttcc
     7861 tgtgatccga aagtcaccat acaggcctat atgacagagc tctctgagca gattctgtct
     7921 tccatggcaa atgatatttt tccgttctct gatatttgtg caaagtacgg gattaattct
     7981 gatctggtat ttgcatatca ggcagagctt ggggatgatt tcccaatcgg tgataccgtt
     8041 gccaggggtc atgacctttc tccggatatg tcaaagatgc ctctgttgat ccaggtaaga
     8101 gaatatgatc ataaatatgt gcttactgca gaataccgca gtgacatgta cagtgaagcc
     8161 tttgtacgtg gaatgctgga atcctatgag gcagctatgg attccctgct gaaagcaaaa
     8221 tatatttcgg aagtttctgt tctttcccaa aatggagcag acaaaatttc ggaatttaat
     8281 aatactgcct gcgaatatga cagaagtaag accatcgctg atatgtttga ggagctggta
     8341 cagaccattc ctgaccatac ggctgtggta tttaaggata aaaaatatac ttacagagaa
     8401 ctggatgaga tcagtgacag acttggaaaa tatatcgcat cccagggaat tggcagtgaa
     8461 gatgttgttt ccattctaat cccccgctgt gaatatatgg cgatcgcacc gatgggcgtg
     8521 ataaaggcag gtgcagctta ccagcctctg gatccaacct atcccaggga ccgcctgatg
     8581 tacatgatgg aggattcctc tgcaaagctt ctcattgttg acagagagct tcttcctctg
     8641 gtagacggat ataaaggacc ggtgctgttt acagatcaga tctggcagct ggaggatagg
     8701 gatgttgtgc ttaagaagcc gcagctgcat gatctgttta tccttttgta tacttccggt
     8761 tccacaggtg tgccaaaggg ctgtatgctg gaatatggaa atattactgc tttctgtcac
     8821 tggttcaaga gatattatgg catagattcg gagtccagga tagctgcata tgcttccttt
     8881 ggttttgatg cctgcatgat ggatatttac ggtgccatca caaacggtgc acagcttcac
     8941 attattccgg aggagatccg tctggatttt attggactgc agcgctattt tgaggaaaat
     9001 ggcatcacgc attcctttat gactactcag gtgggaaggc agtttgcgct ggagatggat
     9061 tgtaagagcc tgagatatct ttctgtagga ggagagaaac tggttccatg tgagccgcca
     9121 aaagattata agtttatcaa tgcttatgga cctacagagg cgactatttt tacgactgta
     9181 tttgaagtgg acaaatatta tccaaatgtc ccgatcggaa aagcacttga caatgtgaag
     9241 ctttatatta cagacaagct ggggcatatg cttcctcccg gtgcatgcgg agagctgatg
     9301 atcaccggct ggcaggtttc cagaggatat cttaacaagc cggaaaaaac tgccgaggtc
     9361 tatacaaaga atctttatga tgatacaccg ggatacgaag tgatgtatca ttcaggtgat
     9421 gtggcaagat ttcttccgga tggaaatatc cagatcattg gcagaaagga ttcccaggtt
     9481 aagatcagag gtttcaggat tgagctttct gaggttgagg aagtgatccg cagatatgag
     9541 ggcatcaggg atgccactgt agttgccttt gatgatccaa atggtggaaa atatattgct
     9601 gcctatgtgg tatcggacag cactgttgat atcaatgccc tgaatgattt tattaaagag
     9661 acaaagcctg cctatatggt acctgcagtt accatgcaga ttgacaaaat tcctctgaac
     9721 cagaaccaga aggtaaataa aaaggctctt cctctgcctg agaaaaaagc agcggagatc
     9781 attaagcctg agaatgaggt tcagcagata ttatttgact gtatcgcaga ggttctgggg
     9841 tatacggatt ttgggattac cacagatatt tatgaggcag gtctgacatc catcactgcc
     9901 attaagctga atatcctgat ctccaaagcc tttgacattg tgatcaaaac ttcagatatt
     9961 aagaatcatc ccactatccg aatgatggag gaatttgtaa aaactgcggg aaaagaaagc
    10021 aaaagggaag tacaggaaag ttatcctctt accaacactc aggaggggat tttcattgag
    10081 tgtactgcaa atatgggttc taccatttac aatatcccgt atctgttaaa gcttgataac
    10141 aaggtggatc tggacagact ggcagaagcc attgacagta ctgttgaggc gcatccttat
    10201 ctgaaaaccc gtctgtttat ggatgacaac ggaaatgtac ttcagaaacg aaacgatggg
    10261 ctcagttata aaacaccgat tttaaacgga atgaacagag acactctggt acgtccatat
    10321 atgttgttta atgaacagct tttccggttt gaaatctaca gaacctgtga tggcaattat
    10381 ctgttcctgg accttcacca cattgttgcc gatggtacat ctctggctat tataattaat
    10441 gatattaaca gagcttacag cggtgagaag ctggaaccgg aaggttatac ttcctatgat
    10501 ctggcactgg ataacagaga tgccctggca ggtgatatct ataaaaatgc agagaattat
    10561 tataagtcag tatttgaaca tgcaggtgga agcatcagct tctatccgga caaaaacggt
    10621 gcggctccaa cagcagaact ttaccacaga gagaccagat ccatttccgt gcaggatgtg
    10681 aaggaattct gtaaaaagca tggaattacg gagaatgtat tcttcatttc cgcttttggt
    10741 atcacacttg gaaaatataa tttcaaaaag gatgctgtat ttaccactat ttaccatgga
    10801 agaaacgatt ccagactttc ggaaacagtg ggtatgctgg taaaaacact ccctgttttc
    10861 tgtgatttct caggaacagc caaagattgc ctgagcggtg tacagaaaca gctgatcgat
    10921 tccatgaaca acgatattta tcctttctca cagatcagcc atgagtttga tattaaggca
    10981 gatgccatgg ttatttatca gggcgacaat tttgcttttg ataccattgg cggggaatat
    11041 gcacaggagg agcctgtcag cttgaacatg gcaaaggcac cggtttctgt cagcatttcc
    11101 attgaaaaga acagatttgt ctttgagatt gagtacagag gggatatgta ccatgaggaa
    11161 actatccggt atctgactga caatctggaa accactgcag agggaatctt aagggaatgc
    11221 gatccggctg atatccggct gatgtttgag gaagaaactc agatggagga tattccggaa
    11281 catgcaggaa agaccttcat agatctgttt aaggagatgg ctgccagata tccggacaga
    11341 ccggcagtgc gggatgactc cggagatttt acttacagag agttggacag aatgtctgat
    11401 tatattgctc agaagcttac ggaaaacgga tttggcccgg aacaggcagc aggtatcctg
    11461 tgcggcagga caaaggaata tacagtagcc tatgtgggtg ttatgaaggc cggcggagcc
    11521 tatgttcctc tggatccgga gtatccacag agcagaattg aatatatgct gaaggattca
    11581 ggagcaagaa atctccttgt gatcgatcag tatcagaatc ttgtggaatt ttatgacgga
    11641 aatgtgatca gtctggacag tgtgtcagat gaggctgagg attttgaact ttctgcagag
    11701 cttatttctc cgaaaccgga gaaccttgcc tatatgatct atacctcagg ctccacagga
    11761 aagccaaagg gtgttatgat tgagcacaga aatctgttga acctgatcga atatatcaca
    11821 ctgagcagaa atacttcacc ggatgacatt gtggcagagt ttgcaagctt ctgtttcgat
    11881 gcgtcagtga tcgatctgtt tgcacctctt accgcaggag cagtcctgta tattttaccg
    11941 gagagtatcc gtaaggacgc cattgccata agcagatata taaaggaaaa agagatcacc
    12001 accgtaacct tccctaccca gatgggagaa ctggttacag aacttctgga ggatgcacct
    12061 gctcttaaat ttgttacact tggcggcgag aaattcaagc attaccgtaa ccgtacctat
    12121 cagatgatca atggctacgg tcctacagag aatacggttt cttccacaga gtttttggta
    12181 gacagacagt atgacaacat cccgatcgga aaatcacagc ggaatgtgcg cagctacatt
    12241 gtggatgaga atctgaaccg gcttccggtg ggtgcgtccg gcgaactttg tcacgcagga
    12301 aggcagattg ccagaggata tcataatctt ccggaaaaaa cagcatctgt gtttgtagaa
    12361 aatccatttg ctgtatgtga gcaggaaagc cgtctttaca ggaccggtga tatggtccgc
    12421 atgaaaggtg acggaaatat tgagtacata ggccggatcg attcacaggt gaagatcaga
    12481 ggatatcgtg tggagcttgg tgagatcgaa ggtgcccttc tgaaacatga gctggtgaaa
    12541 aatgcagccg ttacagtaat tgaaaagggt ggaaataaat atatcacagc ttattataca
    12601 ggagaagcca tcccggagga tgaactgaag accttcctgg agccgctgat cccggattat
    12661 atgatgccgt ctttctttgt cagcattgag gaaatgcctg tgacaccggg cggtaagatt
    12721 gataaaaaag cactgccaat gccggaggta accacgaaca ctgccagcta tgtagagccg
    12781 gttactgcag ctcagagagc actctgtgag atttttgaga aagcactggg aattgaaaga
    12841 gtagggattg aggacaactt ctttgagctg ggcggatctt cccttactgc atccaaggtt
    12901 gctgttatgt gtctgtcaaa gaatatttca ctggtatatg cggatatttt caaatatcct
    12961 actgtacggg aacttgcagc tctggttgat gatgacggag ttacagaggc tgcacagagc
    13021 aagaatgaat tttcggatta taactataac aggatccaga atgtgatcag cgcaaataca
    13081 gaagaaaatg cagaccggat cacaaaggaa aagctgggag atattatggt cacaggtgcc
    13141 acaggtttcc tggggatcca tgtccttaaa gcattccttg acaattatga cggtaaggtt
    13201 tactgtcttg tacgtaaggg caaatatgaa tcgcctgaaa agcgaatgat gaacatgctg
    13261 atgtactatt ttgatgatcc atacaaagag ctgtttgaaa gccgtattat ctgtgtggat
    13321 ggggatatta cctcaaagga acaggtaaca ggattttcag aatacaaatt cagcaccatc
    13381 attaactgcg ctgcctgcgt aaagcatttt gcggctgatg atgtactgga aagaattaat
    13441 gtgcagggtg tggaaaatct gatcgatttc tgtaagaata acggccgcag actgatccag
    13501 atttctacgg tttccgttgc gggagagggt tctgacggtg ttccgccaat gtccagagtt
    13561 ttctgtgaga atgatctgta catcggacag aatattacca acgaatatat ccgcaccaaa
    13621 ttcctggcag agagggcggt tctggaagca gtttccgagg gactggacgg caaggtagtc
    13681 cgggtaggta atctgatgag ccgaaactct gacggcgagt tccagattaa tttcattacc
    13741 aatggattcc ttcgcagcct gagaggttat gcggctgtag gtaaattccc tatgggcggt
    13801 atgcatgagg tggcagaatt ctcaccgatt gattctactg cgctggcagt tctgagactg
    13861 gctcagaccg accggagatt tactgtattc catgcatgta acagccatca tatttatatg
    13921 gcagacctga tctacgcaat gcgcagctat ggattcagga ttgatattgt aagagatgag
    13981 gagtttgagg cagcagtgaa ggaatttgca aagaccggtc aggattctga tgcggtttcc
    14041 ggactgatcg cctatacctc acataatgaa aatgaaatct ataccattga ttacagcaat
    14101 cgttttacag cacaggttct gtacaggctg gattataaat ggccggttac agatgacaga
    14161 tatctggaaa atgcaattgc agcacttgac agacttacat tttttgattg attcaggagg
    14221 gaaaattaca atggaaatta tcacaaaaac agaaggtaac aaagcaacta tggaaatcag
    14281 cggatggctt gatacacaga cagctcccca gttaggggag gctctgtccg gacttgaaga
    14341 cagcatcaca agtctggtat ttgattttac aaatctggag tatatttcat ctgcaggctt
    14401 acgtcaggtg atcgtggcct acaaaaaaat ggctcaaaag gatggattta agatcatcaa
    14461 tgtttctgat gaggtttacg atgtattcag ccttacaggg tttgacagca agatcgatat
    14521 tcagaagaag taactgttga tcagatgcag aaattataca ggatcaatat taatcatttt
    14581 gaggatccgc ttaagaatga aaggcttctg gatctggttg ggatcagaag aagagaaaag
    14641 gtcatcaggt atcgtatgcc tgatgaccgc aaaagaagtc tgggtgcagg gatcatcatc
    14701 agaaaaatcc tcgatgaaaa cgggcttacg gaaagctgcc tgagatattc tgacaatgaa
    14761 aagccggttg tggatggcct tttttttaat gtatctcatg cgggggacta tgttgtgggt
    14821 gtgctgtcag actgcgaagt cgggtgcgat attgagaaaa atgccaatgc gcctcttgag
    14881 gtggcagaac attatttcta ccattcagag cttgcttaca tcaaggctgc gaagaacaaa
    14941 gataaggcgt tttttacgct ctggacatta aaagaaagtt atatgaaaat gacaggcaga
    15001 ggaatgagcc tccctttgga ttcttttgaa gtggttccca cagaagaggg gtttgtcctc
    15061 ggaaaatcct cagaaaggcc atgctttttt gagacaatgg aatttgacgg ttatattttc
    15121 tcggtcagca gtgagagggc tttttctctt cacaatccat tgaaaattgt tttcgacgat
    15181 atttatgtat gatcacagag gatttttcag acgcattcta gagttccaat cagacaggaa
    15241 agcgtatatg tcagatattg cttctgctgt acgggagaac tgaggaaggc atcggagcag
    15301 gtaaaccagg tgtaacaggt atttctggtt gctgctttcc ggtgctttct gtcaattccg
    15361 gatccgagag atttcgggat aaccgtatcc tcttccggga gataatagta atccttataa
    15421 tctgcatagt attgtttcag tttcccgtca gttgttttga taattaaatt gatttcttcg
    15481 tcttttcctg tcagatagaa gtcggtgttt ccattggaaa attcctgtgg cagtgtgcag
    15541 gggagcttca gcttcaggat caggttgtct ccgtcaaatt cactgtatgt aacttcataa
    15601 tctccgtcat aaacgcacag atatcccagc atatcaaaga ttcttcccag tcccagcaca
    15661 tcctccaggt tgtgtcccag gatttcttca gccgtaaaag tctctctttt cttcagaaaa
    15721 tctttgtaaa gtttaatgca ctccttacca ttatcataaa tcctgtcttt gatccccaga
    15781 aattcttcca tgcagggctg tttcatggcg ggcagtttta aaagtgactt taacggtttt
    15841 aatgtcaggt agagatccag agactgtttt cctgtaaatg gagaggggat tccatatttt
    15901 tcatatcgtg cttccagata gggctggtca aatcgttctc cgttgtaaga aatcatcaaa
    15961 ttatattgct gaagaaattg tgaaaaaatt ctcagaattg tctcttcttc actggcattt
    16021 tcggccatcc attgataaaa ataccaagtt tcatcttcaa ttccaacagc tccgatcagg
    16081 tataaatacg tggaatttct tgacaatcct gtggtttcta tgtcgtaaaa aacaggtgta
    16141 aaattgtatt tttggaagag ttttccagtg aaaaaattaa cggtctcaaa gtctggaaac
    16201 ccctgtaaaa taggcatttt tttaacaatc atgttaataa tttttcc
//
