LOCUS       c00294_gnlPro..        14384 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NAGKNJKB_294.
ACCESSION   c00294_gnlPro..
VERSION     c00294_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:52:23
            Original ID  :: gnl|Prokka|NAGKNJKB_294
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14384
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14384
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2041:8576]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2042..8576
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..14384
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14384
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(202..636)
                     /locus_tag="ctg294_1"
                     /transl_table=11
                     /translation="MAKILCVCISKERKTCSQNIHECEADLQGLVGDVHYGMGGRKQVS
                     LLPYEKVKEYFEQSEEEFRYGRFGENLLVEGINWNSIAEGNRFRCGDVLLEAVRIGAGG
                     PASDAYKGEKVCTPMEPWFVFCQILEAGRLREGEIILQQR"
     CDS             complement(853..2055)
                     /locus_tag="ctg294_2"
                     /transl_table=11
                     /translation="MKRNRHHGLNVEFDGLCMDFGHVSLNKKKEFLCGDCYKIEENDED
                     HVLVLSDGLGSGVKANILSTLTATMLSTMIINQVELDEAVRAVAKTLPVCSVRNLAYAT
                     FTVLNFQGKQVSLYQFDNPDAILIRDGKLFDYPVETSMIEEKEIHKSCFELKDEDMLII
                     MSDGVINAGMGKTTNGGWGRDDVMAFCRAKYHKGMSAQEMAGYLAEASLDLNLNETDDD
                     ITAIVLRMRHKQVVNLMIGPPSKEEHDERYLKSFFDSEGYHVICGGTTAQCAARYLDKE
                     LISLSETASGDVPAYYKLEGTELVTEGFLTIEHLLEYCEEWMEDRLSFNRLKRKKDAAA
                     LLGVMLFEQATDINFYFGGAINKSNVELGITEKRKEQAAEELVEHLQNAGKNVNIAFWA
                     I"
     CDS             complement(2042..3766)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg294_3"
                     /sec_met_domain="Fer4_7 (E-value: 2.6e-09, bitscore: 27.2,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.7e-08, bitscore: 23.1,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 5.9e-12, bitscore: 34.8,
                     seeds: 364, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQRFQSILQFKKVSCKNCYKCVRNCPVKAIRVHDHQARIIESQCI
                     YCEKCILVCPQDAKEEQNMIPAICNAMENKTQVIASLHPAYLARFGVTGINGIREAMKK
                     LGFADAADAAEGASLMISQYRALFAEQKEPGIMISSACPVIVQLVKKHYPHLLGNLVQS
                     ASMMQFHASYLKKKYPKAEIVYVSPCISAMSELRDSGNEVDYVITLEELVQWMKKEGIS
                     ITEKEPEQIAYRSREIAIADGLTDLLGAVKGIRRLSVSGMEQCREVLEELHPEDFENCF
                     LEMYACSGGCVAGPSFQMKKGHYLADVLAVKNAAFGKDFHREQGDYELPGFELRKNFGY
                     CSAQEQEEVSEEEIRDALAEMGKFSPKDELNCGACGYNTCREKAIAIIQNKAEVAMCIP
                     YMRAKQESYSNKVFNAMPGLLVTVDYNLKIIQMNEAASKLFNMPKKRRLIGKPVSEIMD
                     DYSLASILAFERNLMQDEIYLEDQKCYLDRVMTNDKENKMILCIMKDITKERKHKDQIH
                     NAQIEAARMADKLVEEQLKIVQQIAGLLGETAADTKVAVEKLKNTILLESEEENEKK"
     CDS             complement(3977..6685)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Molybdop_Fe4S4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Molybdopterin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Molydop_binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH-G_4Fe-4S_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg294_4"
                     /sec_met_domain="Fer4 (E-value: 2.9e-10, bitscore: 29.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2 (E-value: 8.7e-12, bitscore: 34.5,
                     seeds: 206, tool: rule-based-clusters)"
                     /sec_met_domain="Molybdop_Fe4S4 (E-value: 3.4e-13,
                     bitscore: 39.1, seeds: 55, tool: rule-based-clusters)"
                     /sec_met_domain="Molybdopterin (E-value: 1.8e-96, bitscore:
                     313.2, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 9.6e-31,
                     bitscore: 95.8, seeds: 74, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_4 (E-value: 1e-17, bitscore: 53.6,
                     seeds: 126, tool: rule-based-clusters)"
                     /sec_met_domain="NADH-G_4Fe-4S_3 (E-value: 4.8e-19,
                     bitscore: 57.3, seeds: 418, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHLTIDGIPAEVEKGTTILQAARQIGVEIPTLCYLEDVLPDGSC
                     RLCVVEVTNNGRTKFDTACTLRCSEGDEVQTMSEKVVAYRKDTLDLLLSDHRVHCFSCE
                     ANGDCKLQDYCFEYGVTETSYPGEMKDMPIDDTNKFFTYDPSLCILCHRCVNTCKEIVG
                     RGAIDTMDRGFQSVIGAHYKHKWNEGICESCGNCVQACPTGALTMKRRKKYRPYQIDKK
                     VLTTCPHCATGCQYYLLVKDGKIVDTEAVNGPSNKGLLCVKGRSGCFDFVQSPERIKYP
                     LIKNKETGEFERATWDEALDLVASKFMEIKKQYGSDSLAGFACSRSPNEDIYMVQKMVR
                     CCFGTNNTDNCARVCHSASVSGLAMTLGSGAMTNPIEDITKNADLIMLVGSNPEEAHPV
                     VGMQIRQAIKRGCKLIVVDPRDIGLAKKADIHLKLKPGTNVAFANGIMNVILSEGLQDD
                     KFIAERTEGFEELKEIVKDYTPEKVAEICHIDADDLRKAAIMYAKADRAPIIYCLGVTE
                     HSTGTEGVMSMSNMAMMVGKLGREGCGVNPLRGQNNVQGACDMGAQPNVYPGYQKVTDP
                     AVREKFEKAWGVKLDPNIGTHATDVFPKAITGEIKGLYIYGEDPVVTDPDTTHIIKALK
                     SLDFFVLQELFMTETAQYADVILPGVSYAEKEGTFTNTERRVQRVRKAVTVPGEMRLDT
                     DIIIDLMNRMGYPQPHLTSAQIMDEIASLTPSFAGISHERLDSEEVHGQGLQWPCTSKD
                     HPGTPIMHVGKFSRGLGWFYPAKYVPSAELPDEEYPIILMTGRILYHYTTRAMTGKTPE
                     LMEIEGKSFIEMNIVDADKLGIKNGDKVRVSSRRGSIESTARVGTKTSPGESWMPFHFP
                     DGNANWLTNAALDKYARIPEYKVCAIKIEKA"
     CDS             complement(6699..8576)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH_4Fe-4S"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg294_5"
                     /sec_met_domain="Fer4 (E-value: 1.7e-10, bitscore: 30.1,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 2.2e-11, bitscore: 33.1,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.2e-48, bitscore:
                     153.6, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 1.4e-10,
                     bitscore: 30.8, seeds: 130, tool: rule-based-clusters)"
                     /sec_met_domain="NADH_4Fe-4S (E-value: 4.9e-37, bitscore:
                     115.4, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQNKEVLEQIREEAVKELNSYDCRILVCSGTGCVATGSQKIYEK
                     FMEIAKDAPGVTIEFGPHDKDAHVGVKKTGCQGVCELGPLVRIQKGDDVIQYTKVQIED
                     CQEIFEKSVQGNETIERLLYQKGGKVSRGPEDIPFIAKQTRIVLKNCGKFDAESLNEYI
                     ASGGFQALEKAMFEMDPDLVIDQVDKSGIRGRGGGGFPAGKKWIQVARQADPVHYVVCN
                     GDEGDPGAFMDGSVMEGDPYRLIEGMMLAAYAVRAQHGYIYVRAEYPQSVARLKHAIAV
                     LEEVGLLGDDILGTGFSFHMHINRGAGAFVCGEGSALTASIEGNRGMPRVKPPRTVEQG
                     LWAKPTVLNNVETYANIPEIILKGADWYRSIGTEGSPGTKTFSLTGSIENTGLIEVPMG
                     TTLREIIFDIGGGLKSGAAFKAVQIGGPSGGCLTEEHLDVPLDFDSVKKYGAIVGSGGL
                     VVMDEHTCMVEVARFFMGFTQRESCGKCGPCRIGTKRMLEILERIVDGKGEVEDLDKLE
                     HLGNFIKDRSLCGLGKSAPLPVLSTLRNFRDEYVEHIVDKKCAAHVCKAMRSYVIDPEK
                     CKGCTKCARNCPVGAITGNKKEPHSIDTSKCIKCGTCMENCVFGAISVN"
     CDS             complement(8573..9055)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg294_6"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 8.8e-52,
                     bitscore: 164.4, seeds: 130, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDQSFYQKADEIIAFYGKKPASLIPIMQDIQGVYRYLPEELLTY
                     VAEQIGVTEAKAFSVATFYENFSFDAKGKYVIKVCDGTACHVRKSIPVLEELYKKLGLS
                     KTKKTTDDMMFTVETVSCLGACGLAPTMMVNEEVYPRMTPEKADELIDKLRGGEQG"
     CDS             complement(9420..10112)
                     /locus_tag="ctg294_7"
                     /transl_table=11
                     /translation="MSRKVLVVDDEKLIVKGIRFSLEQDGMEVDCAYDGEEAVEKAKDK
                     KYDIILLDLMLPKMDGLEVCQQIREFSNVPIVMLTAKGEDMDKILGLEYGADDYITKPF
                     NILEVKARIKAIMRRAGSDHEEKEKAKSIQVGDLRMDCEGRRVFIAGKEINLTAKEFDV
                     LELLVFNPNKVYSRENLLNIVWGYEYPGDVRTVDVHIRRLREKIETNPSEPKYVHTKWG
                     VGYYFQAQ"
     CDS             complement(10123..11004)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg294_8"
                     /sec_met_domain="SLBB (E-value: 1.6e-13, bitscore: 40.0,
                     seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIKNRCCYTVTLILCGTLFLTGLTGCKSREAQFLIDGLQEAKA
                     EVDAESSEEKTSGQKSKKDTDEKKADTEDRQNDDGSSAEFRKKQAESDGSDAGNGTGSD
                     SGKHTSDADIDNGSEAVSDKEMQQAMIYVDVCGAVANPGVFQLAAGSRVFQAIEAAGGY
                     LPEAALTCVNRAGVLTDGQQLYILTQEEMERQGLDPAEMAKASDGQMNGSAGTGQNTGM
                     AAQVQQDNRININTADEAQLTTLTGIGATRAQAIIAYREENGPFAAIEDIMNVQGIKEG
                     TFAKIKDEIVVG"
     CDS             complement(11101..11535)
                     /locus_tag="ctg294_9"
                     /transl_table=11
                     /translation="MWGFIVALISGALMSIQGVFNTEVTKQTSLWVSTGWVQLSAFAVC
                     VLAWLFTGRESVAALWQVDNKYTLLGGVIGAFITITVIQSMGALGPARAAMLIVISQLA
                     VAYVIELFGLFGVDKEPFEWRKILGLLIAISGIVIFKWQK"
     CDS             complement(11746..13812)
                     /locus_tag="ctg294_10"
                     /transl_table=11
                     /translation="MKKRALILAMIAFIAATTSEPSINMVHAEETQVEETQTEENAGQI
                     SELPIKTLTPKVMDVNPYMAASDSNIHHDCYNTDSTDEVLPVDIYSEINVSYEKVNPNA
                     SPAVFFDSYGHAVVPLLGGLAIRDINAEETQTLGYFSPKQHDNGDYLIQSSYSFVDESN
                     RLVCPTNNNHVLMLKATDEDGNVLPEFEKVLDIDIKAAAEAALGKTLDQNLLSVVFDYE
                     GNLWFATGGFRIYPDRKQQGTFGYVSRTAIDKILNGEDVDLSDAVFVYELEPGEGAENG
                     IAASKEGAVILTNLKCYLLQADNGVKKVWETSYKSVGAKESKEGDETTGGGLAWGGGCS
                     PSLTNDLVMFTDNQDPVNLIAVDMKTGEQVASMPVIDELPEGTQVSVENSAIVYDDGEG
                     TVSTIVCNWFGAGSAKLGEADNDSSIQSYENIYDVGWLRQGNKMIAPGIERVDTVKTED
                     GYEMKSIWCRSDLSDTSMMKLSTATGYIYGYVQDMETGMWQYIMLDFETGETAFTMDIS
                     DKPGYNNMAIGMYAGNSGNALYCPTGYLELLRLQDRFVYLPEMPYRKVNLDQAMRNVLS
                     QEKFAADGGQGDVEGWLNTITIENVHPNTTVAIRMKGISGETGSLKLYAYGTDGTLKEV
                     PAEKWHIQTEDGETPDTLSEDVLYEVHMIVEDGGDFDLSETEKEIKISAVLGA"
     CDS             complement(13839..14213)
                     /locus_tag="ctg294_11"
                     /transl_table=11
                     /translation="VYCIAILTDQEQEGQNCAEYIRNYCTEKKVFPLIEIYQNQEQFFG
                     RIRKTVPAVVFLALPGVSGLNAAEHLRSLYPKCGIIWCSDLDFSLHAFRMWIEYFFMKP
                     VEEQKIKEGLSIWFERRNVI"
ORIGIN
        1 cttttcaata cctttataac ccccggttca attgacggat atattagttt tacctgttga
       61 actctatagc aatttcagag aataatatca ctaagatact ccattagagc cttatttttt
      121 ataaaccaga ttgtcttcag tattttggaa attgctataa catcataata ttcagcccac
      181 tgctgaagaa ttacatattt ttcatctctg ttggagaatg atttctcctt ctctcagcct
      241 ccctgcctcc agaatctgac agaatacaaa ccagggttcc atgggcgtgc ataccttttc
      301 tcccttatag gcatctgatg caggaccgcc cgcaccgatc ctgactgctt ccagaagtac
      361 atctccacaa cgaaatctgt tcccctccgc aatactgttc cagttaatcc cttccacaag
      421 gagattttct ccaaatctgc catatctgaa ttcttcttcg gactgttcga aatattcttt
      481 taccttctca taaggaagaa gactgacctg ctttcttccg cccattccat aatgcacatc
      541 tcccacaagt ccctgcagat cagcttcgca ttcatgaatg ttctgcgagc aggtcttgcg
      601 ttccttactg atgcatacac ataatatctt cgccattttc tgtctcatcc ttcctgatgt
      661 attactgttc actccgttca cagcaacacg cttcgcgatg cacagaattt atgctaatcg
      721 cataaattcg cgcggtatgt ctcgggtttt ctgtgacctt cgctcacaaa aaacacctcg
      781 cgggatatta ccagtgaaca gtaaccctga tatctcttta taaaaccatg tactgctgtt
      841 tttcctgctt tctcagattg cccagaatgc aatattcaca ttctttcctg cattctgcag
      901 atgctccaca agttcttctg ctgcctgttc tttccttttt tctgtgattc ccagttccac
      961 gttactctta ttgatagcac cgccgaagta gaaattaata tccgttgcct gctcaaacag
     1021 catcacacca agcaatgctg ccgcatcttt ttttcgtttc agcctgttaa aggacaacct
     1081 gtcctccatc cattcttcac aatattcaag caaatgctca atcgtaagaa atccctctgt
     1141 caccagctct gtaccttcca gcttataata ggcaggaacg tctccgctgg cagtttcact
     1201 aagagagatc agctctttat ccagatatct ggcagcacac tgtgcagtag ttccgccaca
     1261 gattacatga tatccctctg aatcgaaaaa ggacttcaga tatcgctcat catgctcctc
     1321 cttacttggc gggccgatca taaggtttac cacctgttta tgccgcatcc gcaggacaat
     1381 ggctgtaata tcatcatccg tttcattcag attcagatcc aggctggcct ctgccagata
     1441 gcctgccatc tcctgtgcgc tcatcccttt atggtacttt gccctgcaga aagccattac
     1501 atcatctctt ccccagccgc cgttggtagt ttttcccatt cccgcattga tgacaccgtc
     1561 ggacataatg atcagcatat cctcatcttt cagttcaaaa cagcttttat ggatttcctt
     1621 ctcttcgatc atacttgtct ccaccggata atcaaagagc ttgccatccc ggatcagaat
     1681 tgcatccgga ttatcaaact gataaaggct tacctgtttc ccctgaaaat tcagcactgt
     1741 aaaagtggca tatgccagat ttctcacact gcacacagga agcgtttttg ccactgcacg
     1801 cactgcctca tccagttcca cctgattaat gatcatggta ctgagcatgg tcgcagtcag
     1861 cgtggaaagg atattcgcct ttactccgct cccaagtccg tcagaaagca ccagaacatg
     1921 gtcttcatca ttttcttcaa tcttatagca gtccccacag agaaattctt tctttttatt
     1981 caggctcaca tgaccaaaat ccatgcataa gccgtcaaat tccacattca gtccatgatg
     2041 cctatttctt ttcattctct tcttcactct ccagaagtat ggtatttttc agtttttcta
     2101 ctgccacctt ggtgtccgca gcagtttctc caagaagtcc ggcgatctgc tgtacgatct
     2161 tcagctgttc ttctaccagc ttatctgcca tacgcgcagc ttcaatctgg gcattatgaa
     2221 tctgatcttt atgttttcgt tcctttgtaa tatctttcat aatgcagagg atcattttat
     2281 tttctttatc attcgtcatt acgcgatcca gataacattt ctgatcctcc agataaatct
     2341 catcctgcat cagattccgt tcaaaagcca gtatactcgc cagactgtaa tcatccatga
     2401 tctccgatac cggtttcccg atcaggcgcc gctttttcgg catattgaac aatttggacg
     2461 ccgcctcatt catctgaatg atcttcagat tataatccac agttaccaga agtccgggca
     2521 tggcattaaa gactttattg gagtaacttt cctgttttgc ccgcatatat ggaatgcaca
     2581 tggcaacctc agctttattc tggataatgg caattgcctt ttccctgcat gtgttgtacc
     2641 cgcaggcacc gcagtttaat tcatcctttg gagaaaattt tcccatttcc gccagagcat
     2701 ccctgatttc ttcctctgag acctcttcct gttcctgtgc agaacagtaa ccgaaattct
     2761 ttctcagttc aaatcccgga agttcatagt ctccctgctc tctgtgaaaa tcttttccaa
     2821 aggctgcatt cttcactgcc agaacatctg ccagataatg tcccttcttc atctggaaag
     2881 aaggacctgc cacacagccg ccgctgcatg catacatctc aagaaagcaa ttttcaaaat
     2941 cctccggatg aagttcttcc agaacctccc tgcactgctc catcccactt acagaaagcc
     3001 tgcggattcc ctttacagcc ccaagcaggt ctgttaaacc atccgcaatg gcgatttctc
     3061 tggaacggta ggcaatctgc tcaggttctt tctcagttat ggaaatccct tcttttttca
     3121 tccattgcac cagctcttcc aatgtgatca cataatccac ttcatttcct gagtctctca
     3181 actctgacat agctgaaata cagggactta catagacaat ctctgccttc ggatattttt
     3241 ttttcagata actggcatga aactgcatca tagaggcaga ctgtaccaga tttcccagaa
     3301 gatgcggata gtgtttcttg acaagctgta cgattacagg gcaggcagaa gagatcatta
     3361 ttcccggctc tttctgttcc gcaaaaagtg ctctgtactg cgaaatcatc aggcttgcac
     3421 cttctgctgc atccgctgca tctgcaaatc ccagcttctt catcgcttcc cttattccat
     3481 tgataccggt taccccaaaa cgtgccagat atgctggatg aagagaggct ataacctgcg
     3541 tcttattctc cattgcattg cagattgcag gaatcatatt ctgctcttcc ttggcatcct
     3601 gcgggcagac aaggatacac ttctcacagt aaatacactg actttctatg atcctggcct
     3661 gatgatcatg aacacgtatc gccttgaccg ggcagttccg gacacatttg taacaatttt
     3721 tacaactgac ttttttaaac tgaaggattg actgaaatct ctgcatgcct cgtactcctt
     3781 attatgtaac actatatttt tcacaaaaaa ttatctgtaa ccgttccgta ttttcacaga
     3841 atgatgtact gccgaatgat tatttttgcc tttccataaa ggaatatgga gctgccgcaa
     3901 ggacagcaga tccatgtgcg acagccccat ataatattta cgatatcaga tccggaactt
     3961 tgtctccgat attgttttat gctttctcaa tcttaattgc gcatacctta tattcaggaa
     4021 ttcttgcgta tttgtcaagt gcggcgttgg tcagccagtt tgcatttcca tccgggaagt
     4081 ggaatggcat ccagctctca cccggtgagg tctttgtacc tacacgagcg gtagattcaa
     4141 tggatcctcg tctggaagaa actctgactt tatcaccgtt tttgataccc agcttatcgg
     4201 catctacgat gttcatttcg ataaatgact taccttcgat ctccataagc tcaggtgtct
     4261 ttcctgtcat ggctcttgtt gtgtaatgat acagaatacg tcctgtcatg aggatgattg
     4321 gatattcctc atccggaagc tctgctgacg gtacatattt tgcaggatag aaccagccaa
     4381 gaccgcggga gaatttacca acatgcatga tcggtgttcc cggatgatcc ttggaggtac
     4441 atggccactg aagtccctgt ccatgaactt cttcactgtc aagacgttca tggctgatac
     4501 ctgcgaagct cggtgtcagg gatgcgatct catccatgat ctgagcagaa gtcagatgtg
     4561 gctgcggata tcccatgcgg ttcatcagat caataataat atctgtatcc agtctcatct
     4621 ctccaggtac tgtgacagcc ttgcggactc tctgtacgcg gcgctctgta ttggtaaatg
     4681 taccctcttt ctctgcatag cttacaccag gaaggataac atctgcatac tgagctgtct
     4741 ctgtcatgaa aagttcctga agcacaaaga aatcaagact ctttaatgct ttgataatgt
     4801 gtgtggtatc cggatcagta actaccgggt cctcaccata gatatacaga cctttgatct
     4861 cgcctgtgat tgctttcggg aatacatcag ttgcatgagt tcctatattc ggatcaagtt
     4921 ttacacccca tgctttctcg aatttctcac gaactgcagg atcagtaacc ttctgatatc
     4981 cgggatatac attcggctga gcgcccatat cgcaggcacc ctgtacgtta ttctgtccac
     5041 gaagcgggtt aacaccacag ccttcacgtc caagcttgcc aaccatcatt gccatattgg
     5101 acatggacat aacgccctct gtacctgtgg aatgttcggt tacaccaagg cagtagatga
     5161 ttggagcgcg gtctgctttt gcatacatga tcgctgcttt tctcagatcg tctgcgtcaa
     5221 tgtggcagat ttcagctacc ttctcaggtg tgtaatcttt tacgatttcc tttaattctt
     5281 caaaaccttc ggtacgctct gcaatgaact tgtcatcctg aagaccttca gaaaggatca
     5341 cattcatgat gccgtttgca aaagcaacat ttgtaccagg tttcagtttc agatggatat
     5401 ctgctttctt agccagacca atatcacgag gatcaactac gatcagctta cagcctctct
     5461 tgatagcctg acggatctgc atgccgacta caggatgtgc ttcctcaggg ttggaaccaa
     5521 ccagcataat cagatctgca ttctttgtga tatcctcaat tgggtttgtc atggcacctg
     5581 agccaagagt catcgcaaga cctgatacag atgcggaatg acatacacgt gcacagttgt
     5641 ctgtattgtt ggtgccgaag cagcagcgaa ccatcttctg taccatgtaa atatcttcat
     5701 tcggtgatct ggaacatgca aagcctgcaa gagaatcaga gccgtactgt ttcttgatct
     5761 ccataaattt ggaagcaaca agatccagcg cctcatccca tgttgcacgt tcgaattcac
     5821 ctgtttcttt attcttgatc agcggatatt taatacgctc cggtgactgt acgaaatcga
     5881 agcatccgct gcggccctta acacagagca atcctttgtt ggatggtccg tttacagctt
     5941 ctgtatctac gatctttccg tcttttacaa ggagataata ctggcagcct gttgcacagt
     6001 gaggacaggt agtcagaacc ttcttgtcaa tctggtacgg ccggtatttc tttctgcgct
     6061 tcatggtcag tgcacctgtc ggacaggcct gtacacagtt accgcaggat tcacagatac
     6121 cttcgttcca tttatgtttg taatgtgcac cgatcactga ctggaaacca cgatccatag
     6181 tgtcgatggc acctcttccc acaatctcct tacatgtatt cacgcagcga tgacagagaa
     6241 tacacaagct tggatcatag gtaaagaatt tattggtatc atctatcggc atatccttca
     6301 tttcaccggg atagcttgtc tcagtcacac catattcaaa acagtagtcc tgtaatttac
     6361 agtcaccgtt tgcctcacag gagaagcagt gtacacgatg atcggaaaga aggaggtcaa
     6421 gggtatcttt acgatatgca actaccttct ctgacattgt ctgtacttca tccccctctg
     6481 agcagcgaag tgtacatgcc gtatcaaatt tggttcttcc attgtttgtt acttctacca
     6541 cgcacaaacg acaggaacca tccggcaata catcttccag atagcagagt gtaggaatct
     6601 ccactccgat ctgtctggca gcctgcagaa tggtcgtacc tttttccact tctgcaggaa
     6661 ttccatctat tgtcaaatga atcatctttt caccctcctt aattcacaga aattgcgccg
     6721 aatacacaat tttccataca tgttccgcac ttaatacact tggaggtatc aatgctgtga
     6781 ggctctttct tattgcctgt gatcgcacca accggacagt ttctcgcaca cttggtacat
     6841 cctttacatt tctcaggatc gatcacataa gaacgcattg ccttacatac atgagccgcg
     6901 cactttttat caacaatatg ctctacatat tcatctctga agtttcttaa tgtggaaagt
     6961 acaggaagcg gtgcactctt tccaagtccg cagagtgaac ggtccttgat gaagtttcca
     7021 agatgctcca gtttatccag atcctctact tcaccctttc cgtctacgat cctctcaagg
     7081 atttcaagca tacgcttagt gccaatacgg cagggaccac atttaccgca ggattctctc
     7141 tgagtgaagc ccataaagaa acgtgcaacc tctaccatac aggtatgttc atccataact
     7201 accagaccac cggaaccaac gatcgcaccg tatttcttaa cagagtcgaa atcaagaggt
     7261 acatccaaat gttcttctgt cagacatcca ccggatggtc caccgatctg aacagcctta
     7321 aacgcagcac cggatttcag tcctccgccg atatcaaaaa tgatttctct taaggttgtt
     7381 cccatcggga cctcgatcag acctgtattc tcaatagaac ctgtcagtga gaaagttttt
     7441 gttccaggtg atccctctgt accgatactt ctgtaccagt ctgcaccttt gagaatgatc
     7501 tccggaatat ttgcataagt ttctacgtta ttcagaacag taggtttcgc ccataatccc
     7561 tgttcaactg tacggggcgg ttttacacga ggcatgcctc tgtttccttc gatagatgca
     7621 gtcagggcag aaccttcacc acatacgaaa gcacctgcac cacgattgat atgcatatgg
     7681 aaggagaatc ctgttccaag gatgtcatca cctaacagtc ccacttcttc cagaactgcg
     7741 atagcgtgtt tcagtcgtgc tacagactga ggatactccg cacgtacata aatataacca
     7801 tgctgtgctc ttactgcgta agctgcaagc atcataccct cgatcagacg gtaaggatca
     7861 ccttccatta cggaaccatc cataaatgct cccgggtcac cctcatcacc gttacaaacc
     7921 acataatgaa caggatcagc ctggcgtgct acctgaatcc atttcttacc tgccgggaag
     7981 ccgccgccac cacgtccacg gataccggat ttatcaacct gatcaataac cagatccgga
     8041 tccatctcaa acattgcttt ctccagagcc tggaaaccgc cgcttgctat gtactcattc
     8101 agagattctg catcaaactt accacagttc ttcaaaacaa tacgggtctg tttcgcgata
     8161 aacggaatat cttccggtcc gcggcttact ttaccgcctt tctgataaag cagtctctcg
     8221 atagtctcat taccctgaac actcttctca aaaatctcct ggcagtcttc gatctgaacc
     8281 ttcgtatact ggatcacatc gtcgcctttc tggatacgaa caagtggtcc aagctcacag
     8341 acaccctgac atcctgtttt ctttacacct acatgtgcat ctttgtcatg aggtccaaac
     8401 tcaatggtaa ctcccggagc atctttggca atctccatga atttctcata gattttctga
     8461 gaaccggttg ccacacatcc ggtacctgaa cagacaagaa tacgacagtc ataagaatta
     8521 agttctttca cagcttcttc tctgatctgc tccaatactt ccttattctg gatcatccct
     8581 gttcgccccc tctcagttta tcaatcagct catctgcctt ctccggagtc attctcggat
     8641 atacctcttc attgaccatc atagtcggtg caagtccgca ggcaccaaga caggaaactg
     8701 tttccacagt aaacatcata tcgtctgtcg tcttctttgt ctttgacagc cccagtttct
     8761 tataaagttc ctccagaacc ggtattgatt ttcttacatg acaggctgtt ccgtcacaga
     8821 ccttgatcac atatttacct ttcgcatcaa atgagaaatt ctcataaaat gtggcaacac
     8881 tgaacgcttt cgcttctgtt acgccgatct gctccgcaac atatgtaagc aattcttccg
     8941 ggagatatct gtacaccccc tggatatcct gcatgatcgg aatcagtgat gccggctttt
     9001 taccatagaa agcaatgatc tcatccgctt tctgataaaa tgactgatct agcatttcgc
     9061 accctcctta tacctgtttt ttctcttttt attgcactct ttacatattg taacgttaat
     9121 tatatgcctt tttcgtcatt ttcacaagcg catttataga tattttctaa atttttatca
     9181 ttttcctcta tagatgtttg ttttgtttgt ctaattttta tcagctttgt tcaatactaa
     9241 accatctcag atgtaaacca aactaaacta aatcaaactg aactgccatt cttactctag
     9301 agcgtgtctg aaaaaggctt actgcaagat gtgcgtcaca atcagtccta acaaaaaaca
     9361 gaccgcattt tatgatcttt gtttcataaa atacggtctg tctgtttcac acgttctttt
     9421 tattgagcct ggaaataata tccgacaccc catttggtgt gtacatattt cggttcactt
     9481 ggattggttt caatcttctc acggagacgg cggatatgta catccacagt acgtacatca
     9541 cccggatact catatcccca tacaatgttc agcaggttct cacgactgta aaccttattc
     9601 ggattaaata ccagaagctc cagtacatca aattcctttg ctgtcagatt aatctcttta
     9661 cctgcaataa atacacgtct gccttcacag tccatacgaa gatcgcccac ctgaatgctc
     9721 tttgcctttt ctttctcctc gtggtcgctt cccgcacggc gcatgattgc tttgatacgt
     9781 gccttaactt ccaggatatt gaacggtttg gtgatataat catccgcacc atattcaaga
     9841 ccaaggatct tatccatatc ctcgccctta gctgtcagca tcacaatcgg cacattggaa
     9901 aattcgcgga tctgctggca tacttccagc ccgtccatct tcggcagcat cagatccaga
     9961 aggataatat catatttttt atcttttgct ttctctactg cctcttctcc atcataagcg
    10021 cagtctacct ccataccatc ctgctccaga ctaaaacgga ttccttttac gatcagtttc
    10081 tcatcatcta ctaccaaaac tttcctgctc attcggttct ccttatccta ctactatctc
    10141 atcttttatc tttgcaaaag taccttcttt gataccctgt acattcataa tatcctctat
    10201 cgcagcaaat ggcccgttct cttctctgta ggcaatgatt gcctgcgcac gtgttgcacc
    10261 gatccccgtc agcgtagtaa gctgagcttc atctgctgta tttatgttga tcctgttatc
    10321 ctgctgaacc tgagcggcca tccctgtgtt ctgtcctgtc ccggcacttc cattcatctg
    10381 tccatctgat gctttggcca tctctgcagg atccagtccc tgccgctcca tctcttcctg
    10441 tgtgagaata taaagctgct gtccgtctgt cagaactcct gcacggttta cacaggttag
    10501 agctgcctcg ggaagatatc ctcccgctgc ctcaatcgcc tgaaacaccc ggctcccggc
    10561 tgccagctga aaaactcccg gattcgcaac tgctccgcag acatcaacat agatcatcgc
    10621 ctgctgcatt tccttatcag aaactgcttc tgacccatta tctatatcag catctgaagt
    10681 atgtttcccg gaatcacttc ctgtcccatt acctgcatct gaaccatctg attctgcctg
    10741 ttttttccgg aactctgcag aactgccatc atcattctgt cgatcttctg tatcagcttt
    10801 cttctcatct gtatctttct tcgacttctg tcctgatgtt ttctcttccg atgactccgc
    10861 atccacctct gcctttgctt cctgcaatcc atctatcaga aactgtgcct ctctgctctt
    10921 acatcctgtc agtcctgtaa gaaacaaagt tccacataat atcagtgtca cagtataaca
    10981 acatctgttt tttattttta tcataagggt cctcctctta tttctcagag taagagtccc
    11041 cctgtccata atgccaccct tattgtaacg aaatcttaat gattttacaa tagtaaactc
    11101 ttatttttgc cacttaaata taacaattcc ggaaatcgcg atcagcaatc caaggatttt
    11161 acgccattca aatggttctt tatctacccc aaacaatcca aataattcaa ttacataagc
    11221 aactgccagc tgcgaaataa cgatcagcat tgctgccctg gcaggtccaa gggctcccat
    11281 actctggatt actgtaatgg taataaacgc tccgatcact ccgccaagaa gtgtatattt
    11341 attgtccacc tgccagagtg cagccacact ttcccgtcct gtaaaaagcc aggcaagaac
    11401 gcagactgca aaagccgaca gctgtaccca tccggttgat acccagaggc tggtctgctt
    11461 tgtcacctcc gtattaaaaa caccctgaat gctcatcagt gcccctgaaa tcaatgccac
    11521 tataaatccc cacataaatc tgccctcctg gataatatga tcattctgct tactccggta
    11581 atcatttctg taccgaaaag aggtactgcc gtttagcagc acctcttgtt ttctttagta
    11641 ttagtctatt ctgttttgca gatatcattc ataaaccggg caaataaatg tttcgtttcc
    11701 tcacatatat acttcctgca acaaatccta tttcacaatt tacagtcagg cacccagaac
    11761 agcagatatc ttaatctctt tttccgtttc actgagatca aaatcaccgc catcttccac
    11821 aatcatatgt acctcataca gtacgtcttc ggataatgta tccggtgttt caccatcttc
    11881 tgtctgaata tgccatttct ctgccggaac ttctttcaag gtaccatctg taccatatgc
    11941 atacagcttc agagaacctg tttccccgga gattcctttc atacgtattg caacggtcgt
    12001 attcggatgt acgttctcaa ttgtgatcgt attcagccat ccttccacat ctccctggcc
    12061 gccgtctgcc gcaaatttct cctggcttaa cacattgcgc attgcctgat ccagattcac
    12121 cttgcggtaa ggcatttccg gcagatatac aaacctgtcc tgcagtctca gaagttccag
    12181 atagccggtc ggacaataga gcgcatttcc gctgtttccc gcatacatac cgatagccat
    12241 gttgttgtat cccggtttgt cagaaatatc catggtaaat gcagtctcgc ctgtctcaaa
    12301 atcaagcatg atatactgcc acataccagt ttccatatcc tgaacatatc cgtaaatata
    12361 tcctgttgca gtggacagct tcatcatgga agtgtcagac agatcacttc tgcaccagat
    12421 actcttcatc tcatatccgt cctccgtctt aactgtatcc acacgttcta tacccggtgc
    12481 gatcatttta ttaccctgtc tcagccagcc cacatcataa atattctcat agctttgtat
    12541 tgaggaatca ttatctgctt ctcccagctt cgcacttcct gcaccaaacc agttacatac
    12601 gatcgtgctt actgttccct ctccatcatc atatacaatt gcagaatttt ccacagacac
    12661 ctgtgtacct tccggaagct catctataac aggcatgctc gcaacctgtt ctcctgtttt
    12721 catatccacc gcaataagat ttaccggatc ctgattatct gtaaacataa ccagatcgtt
    12781 ggtcaaagac ggggaacatc cacctcccca tgcaagaccg ccgcctgtcg tctcatcacc
    12841 ttctttgctt tccttggcac ccacactttt ataggaagtt tcccagactt ttttcacacc
    12901 attatccgcc tggagcagat aacacttcag atttgtcaga atgaccgcac cctccttaga
    12961 tgccgcaata ccattctctg caccctctcc cggttccagt tcatatacaa acactgcatc
    13021 tgacagatct acatcttctc cattcaagat cttatcgata gctgtacggg aaacatatcc
    13081 aaaggttccc tgctgttttc tgtcaggata aatgcggaag cctcctgttg caaaccagag
    13141 atttccctca taatcaaaaa ctacagataa cagattctga tccagtgttt ttccaagtgc
    13201 agcctctgct gccgctttaa tatcaatatc cagcactttc tcaaattccg gaagtacatt
    13261 tccgtcttca tctgttgcct tcagcatcag tacatggtta ttattggtcg gacacaccag
    13321 acggttactc tcatctacaa aggaatagga actctggatc agataatctc cattatcatg
    13381 ctgttttgga gaaaaatatc ccagtgtctg tgtttcctct gcattaatat cacggattgc
    13441 cagtccacca agcaacggaa ctactgcatg tccgtaagaa tcaaaaaaga ctgccgggga
    13501 agcattagga ttaacttttt cataagaaac attgatctca gaataaatat caacaggcaa
    13561 tacctcatct gttgaatctg tattatagca gtcatgatga atattggaat cacttgctgc
    13621 catataagga ttcacatcca taaccttcgg tgtaagtgtc tttataggca attctgatat
    13681 ctgacctgca ttttcctctg tctgtgtttc ttctacctgt gtttcctctg catgtaccat
    13741 atttattgac ggttcagatg ttgtagctgc tataaaagcg atcattgcaa gaattaaagc
    13801 tcttttcttc ataattgttt tcctcctgag tgtttttgtc atattacatt tctgcgttca
    13861 aaccagatgg agagtccttc ttttattttc tgctcttcca caggtttcat aaaaaaatat
    13921 tctatccaca tcctgaacgc atgaagcgaa aaatcaagat cactgcacca gataatccca
    13981 catttcggat acagggaacg gagatgttct gccgcattca gcccagacac acctggcaat
    14041 gcaagaaaca ccactgccgg tactgttttt cgtatccgcc caaaaaactg ttcctgattc
    14101 tgatagattt caatcaatgg aaaaactttc ttttctgtac agtaattcct gatatattcc
    14161 gcacagttct gtccttcctg ttcctgatca gtcaatatgg caatacaata cacgacatcc
    14221 ctcctcttcc atttgatgta ctcccatttg ttatcctcat tataaaaaag tcagaatttt
    14281 tttcaataat tctgtcacga aacgacaaaa aatgacacga attgcaaatc tatgatattg
    14341 ttttgtgata tactgttatc agagcgtttt tgaaatagct acac
//
