LOCUS       c00336_gnlPro..        14703 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NAGKNJKB_336.
ACCESSION   c00336_gnlPro..
VERSION     c00336_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:52:23
            Original ID  :: gnl|Prokka|NAGKNJKB_336
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14703
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..585)
                     /locus_tag="ctg336_1"
                     /transl_table=11
                     /translation="MKVKVAETAGFCFGVKRAVNKVYELIDTEQKPIFTLGPIIHNEGV
                     VADLEARGVHVITEADLDFPDDTLQNGTVVIRSHGVGKAIYDKLKEKNISYVDVTCPFV
                     LKIHRIVEKESLAGNHIIIIGDKDHPEVQGICGWCQGPYTVIKNQEEAEAFVPPKGKKI
                     SIVSQTTFNYNKFKDLVEIICKKRYDNNVLNI"
     protocluster    1..14703
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3032:8355]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3033..8355
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..14703
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14703
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(604..1275)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytidylate_kin"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg336_2"
                     /sec_met_domain="Cytidylate_kin (E-value: 2e-78, bitscore:
                     252.6, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGCNIAIDGPAGAGKSTIAKKVAKELSFIYVDTGAMYRAMALYLL
                     NHGVNGENQEEIEAVCSGADISIEYKNGEQIVILNGENVNAMIRTEQVGNMASKSSANP
                     KVRAHLLKLQRTLAEKNDVVMDGRDIGTTILPNAEVKIYLTASADTRAKRRALEYEQKG
                     ESFDLDQIRKDIIERDERDMNREISPLKQAEDAVLVDSSEMGIDDVVNAILNVYKEKVQ
                     K"
     CDS             complement(1461..2921)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HI0933_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg336_3"
                     /sec_met_domain="HI0933_like (E-value: 3.5e-128, bitscore:
                     417.3, seeds: 46, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPVVHIYIDRSEAETWNYDEIDNLQGKINTGEYSMSKVIIIGGG
                     AAGMMAGVFAARNHHEVHILEKNEKLGKKVFITGKGRCNVTNACDTEELFPAMMSNPKF
                     LYSSFYSFTPQDVMEFFEKAGVPLKVERGNRVFPQSDHSSDIIRALERELKKAGAKIHL
                     HTAVQEIVKKPVTESVTDSVNTLESEAALTESGSDAGKSKKGKKSPDIPQEKITGVILT
                     DGTFMEGDAVIVATGGFSYQSTGSTGDGYRFARELGLKVTDIAPSLVPLKTKEDYIPKL
                     QGLSLKNTGLTIKNGKKVLYEDFGEMMFTHFGVTGPMILSASAHIGAKLAKAPNGELSA
                     YLDLKPALTREQLDARILREFEAGPNKQFKNVIGVLFPSSLTPVMLELGGIPAEKKIHD
                     ISREERQHFIDLIKAFPFTITGMGEFKEAIITRGGVSVKEINPGTMESKKISGLYFAGE
                     VLDLDAVTGGYNLQIAWSTAYLAAQAIQ"
     CDS             complement(3033..4445)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: PYC_OADA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: HMGL-like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg336_4"
                     /sec_met_domain="HMGL-like (E-value: 4.3e-47, bitscore:
                     150.5, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 4.8e-59, bitscore:
                     189.1, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELEKKPVKIVETILRDAHQSQIATRMTTEQMLPIVDKLDKVGY
                     HAVECWGGATFDASLRFLHEDPWERLRKLRDGFKNTKLQMLFRGQNILGYRPYADDVVE
                     YFVQKSAANGIDIIRIFDCLNDLRNLQTAVSAANKEKAHAQVALSYTLGDAYTLEYWTD
                     IAKRIEDMGADSICIKDMAGLLLPNKATELVTALKETVKIPIDLHTHYTSGVASMTYLK
                     AVEAGVDIIDTAMSPFALGTSQPATEVMVETFKDTPYDTGFDQKLLSEIADYFRPIRDE
                     ALDSGLLNPKNLGVNIKTLLYQVPGGMLSNLTSQLKEQHAEDKFYDVLEEVPRVRKDLG
                     EPPLVTPSSQIVGTQAVFNVLMGERYKMVTKETKDILLGKYGATVKPFNPEVQKKCIGD
                     EKPITCRPADLLDNELEKLESEMAQYKEQDEDVLTYALFPQVAMDFFKYRQAQKTKVDE
                     KAADKKNGAYPV"
     CDS             complement(4588..5736)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg336_5"
                     /sec_met_domain="OAD_beta (E-value: 5e-157, bitscore:
                     511.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYVTETLSNLIHQTAFFSLTWGNYLMIAVACVFLYLAIKKGFEP
                     LLLVPIAFGMLLVNIYPDIMANPEDMSNGVGGLLHYFYILDEWSILPSLIFMGVGAMTD
                     FGPLIANPISFLMGAAAQLGIYAAYFLAIFLGFNGKAAAAISIIGGADGPTSIFLAGKL
                     GQSALMGPIAVAAYSYMSLVPIIQPPIMKLCTTEKERKIKMDQLRPVSKLEKILFPIVI
                     TIVVCLILPTTAPLVGMLMLGNLFRECGVVKQLTETASNALMYIVVILLGTSVGASTSA
                     EAFLNADTLKIVVLGLVAFAIGTFGGCMLGKLLCKLTHGKINPLIGSAGVSAVPMAARV
                     SQKVGAEADPTNFLLMHAMGPNVAGVIGTAVAAGTFMAIFGV"
     CDS             complement(5753..6121)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 63; E-value:
                     6e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg336_6"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.2e-20, bitscore:
                     63.0, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYTITVNGTAYEVTVEETGSVSAPAAAPKAAPKAAPAAAPKAA
                     APAAGAGAVKVTASVPGKVVKVAASVGQAVKAGDSVVILESMKMEIPVVAPQDGTIASI
                     DVAEGASVENGDTLATMN"
     CDS             complement(6149..6871)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg336_7"
                     /sec_met_domain="OAD_gamma (E-value: 7.6e-28, bitscore:
                     86.8, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFLVMAALVIGSTSAVFAADKVDDTVKSTLVTTAEGLTDAIVQL
                     KDEEIENYMSSGDDFTTSAMQSWQTSKDELGAKKDSNGETTVTFKDDQYTVTVPLKFEK
                     ADANFVYVFDSQGTPTSMSVDVQYGMGKTLQRAGLNTLMGIGTVFVMLILLSLLISLFR
                     FIPNPEAKKAAEAKAAKAAKEAEAAAIAQTAPAQAEENLADDGELVAVIAAAIAAAEGT
                     TTDGFVVRSIRKVKRNRR"
     CDS             complement(6919..8355)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg336_8"
                     /sec_met_domain="CT_Vparvula (E-value: 1.3e-136, bitscore:
                     445.7, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNATQSLAGTRITSLLDANSFVEIGQGVTARSTDFNMTANKAPS
                     DGVITGYGVIDDKLVYVYSQDASVLNGTVGEMHAKKITRLYDLAMKTGAPVIGLVDCAG
                     IRLQEATDALEAFGQIYLKQTLASGVIPQITAIFGTCGGGMAVIPSLTDFTFMESKKGK
                     MFVNTPNALEGNNTDKCDTAAADFQSKETGVIDGVGTEDEILGQIRSLVSLLPSNNEDT
                     DNYTECTDDLNRVCADLANCAGDTAIALSQIADNGEFFETKADYAKDMVTGFIRLNGAT
                     VGAVANRSEVYDAEGKKTETFDGSISARGARKAADFVKFCDAFDIPVLTLTNATGFMAT
                     LCSEKMMAKSVGELVAAFADATVPKVNVIIGKAYGTAYVAMNSKSIGADLVYAWDNAEI
                     GMMDASLAAKIMYADADAAELNEKAAQYRELQNGVASAAARGYVDTVISPADTRKYVIG
                     AFEMLFTKREDRPSKKHGTV"
     CDS             9067..11016
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) baiH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg336_9"
                     /sec_met_domain="baiH (E-value: 2e-141, bitscore: 462.1,
                     seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIKNRIVMMPMGTNYGEQNGEMSFLHINYYKERAKGGTGLIIVE
                     NASVDSPQGSNGTTQLRIDHDNYLPRLYKFCEEIHKYGTCIAIQINHAGASAVSARTNM
                     QPVSASDVPSKEGGEIPRPLSVEEIHHIVKKYGEAAKRAQAAGFDAVEIHAGHSYLISQ
                     FLSPLTNKRTDEFGGSVENRTRFCRMVIEEVRKQVGPFFPIMLRLSADELMEGGNTLED
                     TLEYLEYVQDEVDIFDVSCGLNGSIQYQIDANYMKDGWRSYMPKAVREKFGKPCISMGN
                     IRNPKVAEQILADGDADLIGMGRGLIAEPAWVNKVATGRECDLRKCISCNIGCAGNRIG
                     FNRPIRCTVNPAVLEGDVYKNQKVNKNCNVVVIGGGTAGLEAACTAAEVGCNTFLLEKG
                     ETLGGLASVISKIPAKKRLADFPNYLIHRAEQLENLYIFTNTEGTPENIRKFHPNLIVS
                     STGSAPLLPPIRGLHDRIDKEGSKVASILGMINHINDYPEDMTGKKVVVVGGGAVGLDV
                     VEFFAARNAEISIVEMMDQIGRDLDPVTKNDMKDQMKKHHVAQLTKTALQEVKDSSFLV
                     KDAEGERELPFDYGFVCLGMKAQGQLFAELSDAFVSDDVEILNIGDSKRARRIIDGTLE
                     GRNILNTLTQMGYL"
     CDS             11056..11934
                     /locus_tag="ctg336_10"
                     /transl_table=11
                     /translation="MAERITGHTELIGLMAYPIRHSSSPAMQNEAFAKLGYDYAYLAFE
                     VGADEIEDAVKAIRTLKMRGSNVSMPNKTLVGKYLDELSPAAELCGAVNTIVNDNGHLT
                     GHITDGIGFMSALKDNDIDVIGKKMTIVGAGGAATAIEIQAALDGVAEITIFNRKDEFW
                     DRAVSTVEKINTKTSCHAVLYDLADLDKLKAEMDDSFIFVNATGVGMKPLEGQSVVPDK
                     SYFRPELIVIDVPYSPLETKMRSMAKEVGCKTMNGLGMMLFQGSAAFELWTGEPMPIEH
                     MKEILHISYDD"
     CDS             12203..12964
                     /locus_tag="ctg336_11"
                     /transl_table=11
                     /translation="MNTVQVKNTVIGEGRPKICVPIVGKTKTDILEEAKKITTLPVDVV
                     EWRVDWFDDVFATEKVLETAKELQEVLKDIPVLLTFRTSKEGGEKEISVNDYAALNIAA
                     AQSGYVDLIDVEAFTGDEVVKTIINAAHEAGVKVIASNHDFFKTPEKEEIIRRLCMMQE
                     LGADIPKIAVMPTCKQDVITLLSATLEMSEKYADRPIITMSMAGTGVVSRLTGETFGSA
                     LTFGAASKASAPGQVGVHELKQVLDIIHSSL"
     CDS             complement(13145..14503)
                     /locus_tag="ctg336_12"
                     /transl_table=11
                     /translation="MANTRTQRRENELPYIPFGPFQIRLPFIHYKIESVEFIQGLILGV
                     TALAAVPYLEQYLGLPYELAWSCVIIETFLYLLHSLLGDPVVPGWITPTLPLTIVFLEG
                     FPMGEERIQAMIALQMLVGLVFIFMGVTRLADKFVHAVPNSVKGGILLAAPVTVMAGQL
                     GENGNMHKYPLAIVAGVGLLILISFSDKYQEKRKTNKFLDLVARYGNLFPYLIAMVVGL
                     LVGELDAPGLEIGTFIKIPQFKDIIDQVSIFGVGIPPASMFIKALPLALVCYVIAFGDF
                     VTTETLVSEARHARDDEYIDFNSSRSNLVSGLRNLILSIIAPFPPLSGPLWVGMTVSVS
                     MRYKEGKKAMKSLLGGMASFRLATFLSVLIIPVVSFFRPIFGVGSSITLMFQAFVCARI
                     GMDYCKSDRDKMIAGVMAAVLATQGTAWASAWALAVGFGLNIFLSNWNPFEKK"
ORIGIN
        1 aatatttaaa acattattat catacctctt tttgcaaata atttcaacta aatctttaaa
       61 tttgttgtaa ttaaatgtcg tctgggacac aatgcttatt tttttgcctt ttgggggtac
      121 aaatgcttcg gcttcttcct ggtttttgat cactgtgtac ggtccctgac accagccgca
      181 gatgccctgt acttcggggt ggtctttgtc gccgatgatg atgatgtggt ttcctgcaag
      241 gctttctttt tccacaatcc tgtggatttt cagaacgaag gggcaggtca catctacata
      301 agagatgttt ttttctttca gcttatcgta gatggctttg cctacaccgt gagagcggat
      361 gactactgtt ccgttctgca gggtatcatc cgggaaatcc aagtctgctt ctgtgataac
      421 atggacgcca cgggcttcca gatccgctac tacgccttcg ttgtggatga tcgggcccag
      481 agtgaaaata ggtttctgtt ctgtgtctat gagttcgtag actttgttca ctgcacgttt
      541 aacgccgaag cagaagcctg ctgtttctgc tacttttact ttcataaaat aatccttctt
      601 aaattatttc tgcacttttt ccttatatac attaagaatc gcatttacaa catcatcaat
      661 tcccatttcc gaggaatcta cgagcactgc gtcctctgcc tgtttcagag gggagatttc
      721 gcggttcatg tcgcgttcgt cgcgctcgat gatgtctttt cggatctggt ccaggtcgaa
      781 ggattctccc ttctgttcat attccagtgc tcttcttttt gctctggtgt ctgcgcttgc
      841 tgtgaggtag atttttactt ctgcgtttgg aaggatggtt gtgccgatat ctctgccgtc
      901 catgactacg tcgtttttct ctgccagagt tctctgaagt ttcagaaggt gggctctgac
      961 tttcgggttt gcggagcttt tggatgccat gtttcctacc tgttcggtgc ggatcatagc
     1021 atttacgttc tctccgttga ggatgacaat ctgttctccg tttttgtatt cgatggagat
     1081 gtcagcgccg gaacatacag cctcgatctc ttcctgattt tctccgttta cgccatggtt
     1141 cagaagatat aaagccattg ccctgtacat ggctcctgta tctacataga taaatgataa
     1201 ttctttcgct actttctttg cgatggtgct ctttcctgct cctgcaggtc cgtcgatggc
     1261 tatgttacat cccattttcg tggttcctcc tgtttctatt attcaaacag attttctctg
     1321 ttttattatt aatgtttatt aatcagtcaa gcggatattc gcaatccgct tcgctacttg
     1381 ctcataaccg aatcatagat ataattcgca tacacggtac tcatcatctg cttgtttctg
     1441 ttgtttctat agtaagcaac ttactgtatg gcctgtgctg ccagatatgc ggtagaccag
     1501 gcaatctgta agttatatcc acctgtcact gcatccagat ccagtacctc gcctgcgaag
     1561 taaagacctg agattttctt tgattccatt gttccgggat tgatctcttt gacagagacg
     1621 ccgcctctgg taatgatggc ttctttgaac tcacccattc ctgtgattgt gaaggggaag
     1681 gctttgataa ggtcaatgaa gtgctggcgt tcttctctgg agatatcgtg gattttcttc
     1741 tctgcgggga ttccacccag ttccagcatt accggagtca gagatgacgg gaaaagtacg
     1801 ccaatcacgt tcttgaactg tttgtttggt cctgcttcaa attcgcgcag gatcctggca
     1861 tccagctgtt ctctggtaag tgccggcttc agatccagat atgcagacag ttcgccgttt
     1921 ggtgctttcg ccagttttgc accaatgtgg gcactggcgg acaggatcat gggacctgtg
     1981 actccgaaat gggtgaacat catctctccg aaatcctcat agagtacttt ctttccattc
     2041 tttatggtaa gtcctgtatt cttaagggaa agtccctgaa gcttagggat atagtcttct
     2101 tttgtcttta atgggacaag agaaggtgca atgtctgtga ccttcaatcc aagttctctt
     2161 gcaaagcggt atccatcgcc tgttgagccg gtgctctgat aagagaatcc gccggttgcc
     2221 acgatgactg catctccttc catgaaggtt ccgtctgtaa ggatgactcc tgtgatcttc
     2281 tcctgcggta tgtcaggtga tttttttcct tttttgcttt ttcctgcatc agatcctgat
     2341 tctgttaatg cggcttctga ttcaagggta tttacggaat ctgttacaga ttccgttaca
     2401 ggtttcttta caatttcctg tacagcagtg tgaagatgaa tctttgctcc tgctttcttc
     2461 agctcacgct ccagagcgcg gatgatgtct gaggaatggt cagactgtgg aaatacgcgg
     2521 tttccacgct ctaccttcag agggacaccc gctttctcaa agaactccat tacatcctga
     2581 ggggtaaatg aatagaaact gctgtagagg aacttgggat tgctcatcat tgcaggaaag
     2641 agttcttctg tgtcgcaggc atttgttaca ttgcatctgc cttttcctgt gatgaagact
     2701 ttctttccca gtttctcgtt cttctctaat atatgaactt catgatggtt acgggctgca
     2761 aaaacccctg ccatcattcc ggcggctccg ccgccgatta ttataacttt gctcatggaa
     2821 tattctcctg tatttatttt accctgcaga ttgtctattt catcatagtt ccacgtctcc
     2881 gcttcgctac gatcaatata gatatgtacc actggcagca tatacccatt ggcacattat
     2941 attcccgggt atcatattct ttcataataa cgcaaaggag cctgcttacg caagctcctt
     3001 ttttcgtttg gacatattta attactgatc aattatacag gatatgctcc gttctttttg
     3061 tcagctgctt tctcgtcaac ttttgttttc tgagcctgac ggtatttgaa gaagtccata
     3121 gctacctgtg ggaacagtgc gtatgttaat acgtcttcat cctgttcctt gtactgagcc
     3181 atttcgctct caagtttctc aagctcgttg tcaagaaggt ctgcaggacg gcatgtgatc
     3241 ggtttctcat cgccgatgca cttcttctgt acttccggat taaacggttt tacagttgcg
     3301 ccgtattttc ctaacaggat atcttttgtt tcttttgtaa ccattttgta tctctcgccc
     3361 ataagtacgt tgaatacagc ctgtgtacca acgatctgtg aagacggagt aacaagtggc
     3421 ggttcaccaa ggtctttacg tacacgcgga acttcctcga gaacatcgta gaatttgtct
     3481 tctgcgtgct gttctttcag ctgggaagtc aggttggaga gcataccgcc cggtacctgg
     3541 tacagtaaag tcttgatgtt aacaccaagg ttcttaggat tgagcagtcc gctgtcaaga
     3601 gcttcgtcac ggatcggacg gaagtagtca gcgatctcgg agagaagctt ctgatcaaat
     3661 cctgtgtcgt atggtgtatc cttgaatgtc tcaaccataa cctctgttgc aggctgggat
     3721 gttcccagtg caaatggaga cattgctgta tcgatgatat ccacacctgc ttctactgct
     3781 tttaagtaag tcatggaagc tacacctgag gtgtaatgtg tatgaaggtc gatcgggatc
     3841 ttaactgttt cttttaatgc tgttacaagc tctgtagctt tgtttggaag gagaagacct
     3901 gccatatctt tgatacagat ggaatcagcg cccatatctt caatacgttt tgcaatgtct
     3961 gtccagtatt ccagtgtgta agcatctcct aatgtatagg aaagagctac ctgtgcatga
     4021 gccttctctt tgtttgcagc gcttactgct gtctgcaggt tacgaaggtc attgaggcag
     4081 tcaaaaatac ggatgatgtc gattccgttt gcagcagatt tctgtacgaa gtattctaca
     4141 acgtcatctg catatggacg gtatccaagg atgttctgtc cacggaaaag catctgaagt
     4201 tttgtgtttt tgaagccgtc acgtaattta cgaagtcttt cccatggatc ttcgtgaagg
     4261 aaacgaaggg atgcatcgaa tgttgcacca ccccagcact ctactgcgtg atagccgact
     4321 ttatcaagtt tatctacgat cggaagcatc tgttctgtgg tcatacgtgt tgcgatctgg
     4381 gactgatgag catcacggag aatggtttcc acaattttaa caggtttttt ctctaattct
     4441 gccattatta aatctccttt atagttctgt ttaatcggat attcgcaatc cgcttcgcta
     4501 cttgctcata accaaatagc tgctccgcag cttatcagaa ggagttgcac tcctcctgat
     4561 acaagcaaga tagcttgctt gatttggtta tactccgaaa atagccatga atgttccggc
     4621 tgctacggct gtaccgataa caccggcaac gttcgggccc attgcgtgca tcagaaggaa
     4681 gtttgtagga tctgcctctg cacccacttt ctgggataca cgggctgcca taggtactgc
     4741 ggatacacct gcggaaccga tcagcgggtt gatctttcca tgagtcagtt tgcagagcag
     4801 tttaccaagc atacatccgc cgaatgtacc gattgcgaat gcaacaagac ctaaaactac
     4861 gatcttcaga gtatctgcgt ttaagaatgc ttctgcactt gtggaagcac ctacggatgt
     4921 acccagaagg ataactacga tatacatcag ggcattggaa gctgtttctg tcagctgttt
     4981 tacaacaccg cactctctga acaggttacc aagcatgagc ataccaacca gcggagctgt
     5041 tgtaggcaaa atcaggcaga caacgattgt gataacgatc gggaacagga tcttctccag
     5101 tttggaaacc gggcgaagct gatccatttt gatcttacgt tctttctctg ttgtgcagag
     5161 tttcatgata ggcggctgga tgatcggaac cagtgacata taggaatatg ctgccactgc
     5221 gatcggtccc atcagtgcag actgtccaag tttacctgca aggaaaatgg aagtcgggcc
     5281 atcagcacca ccgatgatgg agatagctgc cgctgctttt ccgttgaatc caaggaagat
     5341 tgcaaggaag taagctgcat agataccaag ctgtgctgca gcacccatca ggaagctgat
     5401 cgggtttgca atcagcggac cgaagtctgt catggcacct acacccatga agatcaggga
     5461 tggtaagata ctccactcat caaggatgta gaaataatga agaagtccac ctacaccatt
     5521 agacatatct tccgggtttg ccataatgtc cggatagata tttacaagca gcataccgaa
     5581 tgcgatagga acaagcagaa gcggctcgaa tcccttcttg atagcaaggt aaaggaatac
     5641 gcaggctact gcgatcatca ggtaattgcc ccatgtcaaa ctgaagaatg ctgtctgatg
     5701 aatcaggttg gacaatgttt ctgttacata agacatttga ctacctcccg tcttagttca
     5761 ttgttgctaa agtatctccg ttttctacag aggcaccttc tgcaacatca atgcttgcga
     5821 tagtaccatc ctgaggagct actacaggga tttccatttt catggattca agaataacta
     5881 cgctgtctcc ggcttttact gcctgtccaa cgcttgctgc tactttgaca actttgccag
     5941 gtacggaagc agttactttt actgcgccgg cgcctgctgc aggagctgct gctttcggag
     6001 ctgctgcagg tgcagcctta ggtgctgctt ttggagctgc tgcaggagcg gatacgcttc
     6061 ctgtttcttc aacagttact tcatatgctg taccatttac tgtaattgta tagcttttca
     6121 ttttaaaatc ctcctaaata aatgacaatt atcttctatt tctttttact ttacggatgg
     6181 aacgaactac gaagccgtct gttgtagttc cttctgctgc tgcgatggct gctgcgataa
     6241 cagctaccag ctctccgtca tctgcaaggt tctcttctgc ctgtgcaggt gctgtctgtg
     6301 cgatggctgc tgcctctgcc tcttttgcag ctttggctgc ttttgcttct gctgctttct
     6361 ttgcttccgg attcggaata aatctgaaca gagaaatcag aaggcttaat aaaatcagca
     6421 ttacgaatac agttccaata cccatcaaag tattaaggcc tgctctctga agagtcttgc
     6481 ccataccata ctgtacatct acagacatgg aagtcggtgt tccctgtgag tcaaagacat
     6541 atacaaagtt tgcatctgct ttctcaaatt taagaggaac agtaactgtg tactgatcat
     6601 ctttgaaagt tacagtggtt tcaccattgc tgtccttctt tgcgccaagt tcatccttgg
     6661 atgtctgcca ggactgcatg gcacttgttg taaagtcatc tcctgaactc atgtaattct
     6721 cgatttcttc atctttaagc tggacaatgg catctgtcag tccttctgct gtagttacca
     6781 gtgtggactt aacagtatca tcaaccttat ctgcggcaaa taccgcagag gtgctgccga
     6841 tcaccagcgc agccattacg agaaatgtca tgaatacaga agttattttt ttgatcattt
     6901 tcatatgcgt caccccgctt agaccgttcc atgtttctta gacggacgat cttctctctt
     6961 tgtgaacagc atctcaaatg caccgattac atattttctt gtgtcagccg ggctgatcac
     7021 agtgtcaaca tagcctcttg ctgctgcgga agcaacacca ttctgaagct ctctgtactg
     7081 agcagctttt tcattcagtt cagcagcatc tgcatctgcg tacatgatct tggctgccag
     7141 ggaagcatcc atcataccga tctctgcgtt atcccatgca tatacaaggt ctgcaccgat
     7201 agatttgctg ttcattgcca cgtaagctgt accgtaagct ttgccgatga tcacatttac
     7261 cttcggaaca gttgcatctg cgaatgcagc taccagttca cctacggatt tcgccatcat
     7321 cttctcgctg cataaggttg ccatgaagcc tgttgcgttt gtaagtgtaa gtaccggaat
     7381 atcaaaagcg tcgcagaatt tcacgaaatc tgctgctttt cttgcgcctc ttgcagagat
     7441 gcttccgtca aatgtttctg ttttcttgcc ttctgcgtca tatacttcgc ttctgtttgc
     7501 aacagcacct actgtagcgc cgtttaaacg gataaagcct gtaaccatgt cttttgcata
     7561 gtctgctttt gtctcgaaga attcaccgtt gtcagcgatc tgggaaagtg cgattgctgt
     7621 gtcacctgca cagtttgcaa gatctgcgca tacgcggtta agatcgtctg tacactctgt
     7681 gtaattgtct gtgtcttcat tattagaagg aagaagtgat actaaggaac ggatctggcc
     7741 aagaatctca tcctctgtac caacgccatc gatcacacct gtctctttgc tctggaaatc
     7801 agctgctgct gtatcgcatt tgtctgtgtt gtttccttcc agtgcgtttg gtgtgttgac
     7861 gaacattttt ccttttttgg attccatgaa tgtgaaatct gtcagggacg ggataactgc
     7921 cataccaccg ccgcatgttc cgaagattgc tgtgatctgc gggatcacac cggatgccaa
     7981 tgtctgtttc agatagatct gtccgaaagc ttccagtgcg tctgttgctt cctgaagacg
     8041 gatacctgca cagtcaacaa gtccgataac cggagcgcct gttttcatgg caagatcata
     8101 aagtcttgtg atcttctttg catgcatttc accaacagta ccgtttaata cagatgcatc
     8161 ctggctgtat acataaacca gtttgtcatc gatcacacca tatccggtga taacaccgtc
     8221 agatggtgcc ttgtttgcag tcatgttgaa atctgtggat ctggctgtta caccctgtcc
     8281 gatttcgaca aaactgtttg cgtcaagcaa agaagtaatt cttgtgcctg ctaagctttg
     8341 tgttgcatta ctcattcttg tttgccctcc atctttatga gaatatttaa aagttaaccc
     8401 aaaaatttag ccgattttaa ttttaccttt tccggcagaa aatttcaaca tttatttgtc
     8461 attttcgtta aaaatatagc agaaaaattt gtcaggtttc tccaaatttt gtttttttga
     8521 gtatttcttc ctatttaata gagggtatta cggttatttt gtattgtcct gtatttcacc
     8581 ctctcccgca aaccagtgtg tcgacaagtt gatttctcga acaatcctgc gtctgaattt
     8641 cttatttcta tcctgcaaga ttgtttcaag aatcaacttg tcggcacacc agagcgtgtt
     8701 tgaagcaact ataccacaca cttgtctgcg aatccgactg cacaggtata aaagtctcag
     8761 cgcagcccgg cgaaacaata ctatagccat acaggttcag caggattttc ccatgatgtg
     8821 gatgcagttg cgaatgcttt cattcagtac gcggacagtg cacggaaaac catagatgtt
     8881 ttttattata tagcacgaat tatcaattag atttatggat tatcccgtta tataattaac
     8941 acatcaaaga aattcaggcc acagctaaag cactgaacag ctatagatac aacagaaaat
     9001 ttcaggagga aagacgtaat gaaaagcaat taccagcata ttttcacacc actcacagta
     9061 aaaaatatga ctatcaaaaa ccgtatcgtt atgatgccta tgggaaccaa ttacggggaa
     9121 cagaacggcg aaatgagttt tcttcacatt aattattata aagagcgtgc caaaggcggc
     9181 acaggtctga tcatcgtaga gaatgcaagc gtagattctc cgcagggttc caacggaact
     9241 actcagcttc gtattgacca cgacaactat ctgccgcgtc tgtacaaatt ctgtgaagag
     9301 atccacaaat atggtacctg tattgcgatc cagatcaacc acgcaggtgc ttccgctgtt
     9361 tccgcacgta caaatatgca gccggtttcc gcatctgatg ttccgtccaa agaaggcgga
     9421 gaaatcccgc gtccgttatc agtggaagaa atccatcaca ttgtaaagaa atacggcgag
     9481 gctgcaaaga gagcccaggc tgcaggtttt gacgcagtag aaatccatgc gggacattcc
     9541 tatctgatca gccagttcct ctctcctctt acaaacaaac gtacagatga gttcggcgga
     9601 tctgtggaaa acagaacacg tttctgccgt atggtcattg aagaagtaag aaaacaggtc
     9661 ggacctttct tcccaatcat gctccgtctc agcgcagatg agctgatgga aggcggcaac
     9721 actcttgagg atactcttga atatctggaa tatgttcagg atgaagttga tatcttcgat
     9781 gtttcctgcg gtttaaacgg ttctatccag tatcagatcg atgccaacta catgaaagac
     9841 ggatggcgtt cctatatgcc taaagctgtc agagagaaat tcggcaagcc atgtatctcc
     9901 atgggaaata tccgtaaccc gaaggttgcc gagcagatcc tcgctgacgg cgatgcagac
     9961 ctgatcggta tgggacgtgg tcttatcgca gaacctgcat gggtgaacaa agtagctaca
    10021 ggcagagaat gtgaccttcg caaatgtatc tcctgtaaca tcggatgtgc aggaaacaga
    10081 atcggcttta accgtccgat ccgctgtact gtaaacccgg ctgttctgga aggtgatgtt
    10141 tataagaatc agaaagtgaa caaaaactgt aatgttgtag taatcggagg cggtactgcc
    10201 ggactggaag ctgcctgtac agccgcagaa gtaggctgta ataccttcct tctggaaaaa
    10261 ggtgagactc ttggcggtct tgcttctgtg atctctaaga ttcctgcaaa gaagcgtctg
    10321 gctgatttcc cgaactatct gattcacaga gcagagcagc ttgagaatct ttatatcttc
    10381 acaaacacag aaggaacacc ggaaaatatc cgcaaattcc atccgaacct gattgtaagc
    10441 tccacaggtt ccgcgccact gcttcctccg atcaggggac ttcacgaccg cattgacaaa
    10501 gaaggcagca aggttgcttc tatcctggga atgatcaatc acatcaatga ctatccggaa
    10561 gatatgacag gcaagaaggt tgttgttgtg ggcggcggtg ctgttggtct tgatgttgtg
    10621 gaattctttg cagcaagaaa cgctgagatt tctattgtgg agatgatgga tcagatcgga
    10681 cgtgacctgg atcctgttac aaagaatgac atgaaggacc agatgaagaa acatcatgtg
    10741 gcccagctta caaagacagc tcttcaggaa gtaaaagaca gctctttcct tgtaaaagat
    10801 gcagaaggtg aacgtgagct tccatttgac tacggattcg tatgtcttgg tatgaaagct
    10861 cagggacagc ttttcgcaga gctttccgat gcttttgttt ctgatgatgt tgagatcctg
    10921 aacatcggag acagcaaacg tgcaagaagg atcatcgacg gaactctgga aggaagaaat
    10981 atccttaata cactgactca gatgggatac ctttaacaaa aacctttaca acaaaatacg
    11041 aaaggggata ttataatggc tgaaagaatt accggacata ctgaattaat cggtctgatg
    11101 gcttacccga tccgtcactc cagctctcct gcaatgcaga atgaggcttt tgcaaaactc
    11161 gggtatgact acgcttacct tgctttcgag gttggcgcag atgaaattga ggatgcagta
    11221 aaagcaatcc gtactctgaa aatgagagga tccaatgttt ccatgccaaa caaaactctg
    11281 gttggaaaat acctggatga gctttctcct gctgcagaat tatgcggtgc agttaacacg
    11341 atcgtaaatg acaacggtca tcttacaggt catatcactg acggtatcgg atttatgtct
    11401 gccctgaaag ataatgatat tgatgtgatc ggaaagaaaa tgaccattgt tggtgcaggc
    11461 ggtgctgcca ctgccatcga gatccaggct gctttagacg gtgttgccga gatcacaatc
    11521 tttaaccgca aggatgaatt ctgggatcgt gcagtatcca cagtagagaa gatcaacaca
    11581 aagacatcct gccatgcagt tctttatgat ctggcagatc ttgataaact gaaagctgag
    11641 atggatgaca gttttatctt tgtcaatgct acaggtgtgg gaatgaaacc actggaagga
    11701 cagtccgttg ttccggacaa gtcttacttc cgtcctgagc tgatcgttat agatgttcct
    11761 tactctcctc tggaaacaaa aatgcgttcc atggccaagg aagttggatg caagacaatg
    11821 aatggtctgg gaatgatgtt attccagggt tccgctgcat ttgagttatg gacaggcgaa
    11881 ccaatgccta tcgaacatat gaaagagatt cttcacatct cctatgatga ctgatacctg
    11941 atggtatctt cagtaaagat atctcatatt gtgatgcaga acagatcatt tcactgatct
    12001 ttctgcacat aatatttgat atataccgct tttcggcgta ctgcaggaga tgtactgata
    12061 tattactccg cgcagaatgt acatatcctg cagtttgctt caaaaagctg ttgatcatgc
    12121 ggttatgtta cggttattct tataacagtt ccataataat ccggaactac tataatacaa
    12181 cagaaaatat gaggataaac agatgaacac agttcaggta aaaaacactg tgatcggcga
    12241 gggcagacct aagatctgcg ttcccatcgt aggaaaaaca aaaacagaca ttctcgaaga
    12301 agccaaaaag atcactactc ttcctgttga tgtagttgag tggcgtgttg actggttcga
    12361 tgatgtcttt gctactgaga aagtattaga aaccgctaaa gagcttcagg aagttttaaa
    12421 agacattcct gttctcctta cattccgtac ttccaaagaa ggcggtgaga aagaaatttc
    12481 tgtaaatgac tatgctgctt taaatattgc agctgctcag agcggttatg tagatttaat
    12541 tgatgtagaa gcatttacag gtgatgaagt tgttaagaca atcatcaatg ctgctcatga
    12601 ggcaggtgta aaggtaattg cttccaacca tgatttcttt aagactccgg agaaggagga
    12661 gatcatccga cgcctctgca tgatgcagga gctgggtgct gatatcccta agattgcagt
    12721 aatgcctacc tgtaagcagg atgttatcac actgctgtct gccactctgg aaatgtctga
    12781 gaaatatgca gaccgcccga tcattaccat gtccatggca ggaacaggcg ttgtaagccg
    12841 tctaacaggt gagacattcg gctccgctct cactttcggt gctgcttcca aagcttctgc
    12901 tccgggacag gtcggtgtac atgaattaaa acaggtgctg gatatcattc acagcagcct
    12961 gtgatctgtt gatgaatgat gtgatatcag atgttattct tgcctatagc tgatatcact
    13021 catattcgtc aacagattgt tacagaattt gaatttaata attatgactc cttaaaataa
    13081 taattgatga aaaccaagaa gaacagccct gaatcccggc tgttcttctt ggttttcgtt
    13141 tatattattt tttctcaaag ggattccagt tggacaggaa gatattcagt ccgaagccta
    13201 ctgccagtgc ccatgcagat gcccatgcgg ttccctgggt tgcgaggact gctgccataa
    13261 cgcctgcaat catcttgtct ctgtcgctct tacagtaatc cataccaatt ctcgcacata
    13321 caaacgcctg gaacatcaga gtaatggaag atcctactcc gaagatcgga cggaagaagc
    13381 ttactacagg aatgatcagc acacttaaga atgtggccag tctgaaagaa gccattcctc
    13441 cgagaagaga cttcattgct ttctttcctt ctttataacg catggatacg gatacagtca
    13501 ttccaaccca taacggaccg gaaaggggag gaaatggtgc aatgatggaa aggatcaggt
    13561 ttctcagacc gcttaccaga ttggaacggc tggaattgaa atcaatatac tcatcatctc
    13621 ttgcgtgacg tgcctctgat acaagagtct ctgtagtaac aaaatcacca aatgcaataa
    13681 catagcacac cagtgccagc ggcagtgctt tgataaacat agatgcagga ggaatcccta
    13741 cgccaaaaat gctcacctga tcaatgatat ctttaaactg aggaatcttg ataaaagtac
    13801 caatctccag tcccggagca tccagttctc caaccagaag tcctactacc attgcgataa
    13861 gatatgggaa gagatttcca tatcttgcaa caagatcaag aaacttattt gtttttctct
    13921 tctcctgata tttgtcagag aagctgatca ggatcaggag gcctacacct gcaacaatag
    13981 ccagaggata tttgtgcata tttccgttct ctcccagctg ccctgccata actgttacag
    14041 gtgccgcaag aaggatacct ccttttacag aattggggac tgcatgaaca aatttatccg
    14101 ccagtctggt cacacccata aagataaata ccagacctac caacatctgc agtgcgatca
    14161 ttgcctggat tctctcctct cccataggga agccttccag aaatacgatg gttagaggca
    14221 gtgtgggtgt gatccatccc ggtacaaccg gatcacctag cagactgtgc agcagataaa
    14281 gaaatgtctc aataattaca cagctccacg ccagctcata aggaagcccc agatactgct
    14341 ccagataagg aacagctgcc agtgctgtta cgcccaggat cagaccctga atgaactcaa
    14401 cagattctat cttgtaatgt atgaatggaa gtcttatctg aaatggtcca aaggggatgt
    14461 agggcagttc attttctctt ctttgtgttc ttgtatttgc catacagatt ctccttttca
    14521 ataaattgtt agattacttc tatatttcag cttgtatatt ctatcttttt gttaattttt
    14581 agacaatccg gattttaata aaatccactc cgcccggaaa aaatttgaag cttgtaacgg
    14641 cctaacggat cttcagttgg attggttttt tattattttt tatttcaagg ggtggatcgg
    14701 ggg
//
