LOCUS       c00009_gnlPro..        16678 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CPHBBEFF_9.
ACCESSION   c00009_gnlPro..
VERSION     c00009_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:52:48
            Original ID  :: gnl|Prokka|CPHBBEFF_9
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16678
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16678
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3685:6678]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3686..6678
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16678
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16678
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(235..2367)
                     /locus_tag="ctg9_1"
                     /transl_table=11
                     /translation="MKKIQKKLSVVLAVMMVLCMFTALPFSASAAETSEETSAGNKINV
                     TSNVTDPVSYDYNAQTEQVVVTYLLKADHMIVDTQSSLTYDSKVLKLASTTTTNTKKKV
                     FPVFQSSIVWNTSITNQVYFNCSSLDLFNFKSENVYCTFTFDVVGSGDTTVNLNVDYLT
                     GTEAESYDDFFESEKKDIDYIYDSANKVEGAAFTAKAVLVQGEEPTTAPQPTTVTQPTT
                     ATQPTTAPATKPTQPATEPTTTPSGDGATIKFAAPTSQASRYNWSKPVLFYGNTQSVDK
                     STKLSMTATSEKYYTTEVGSNTLLTTNGWTVYELKISKDQAAAINSSKFVGFATANGVN
                     RTTLVSGSNVLKAGVDTYTAKYGTTANTVAALDGKTFVIRDSAYGATSSVSFVGYWVSD
                     FVTVRAAAPLAATSYSTWDNVDLYYGNTTAFDSMTKLSMINTGDTTKVSSLNGNMTIKT
                     GRWYIYAITLDKATASAVENAKYVGFNKTDAVNRTAILKNVLFAKTNTFDGNYNSKART
                     LSELDGQLFVIKGMTAKSSSVATYTGEWETKDVYTQGKDDTVTLYFAAPKGVKNYANWD
                     TGVQLYYSNDNVYTKAERIDMKKVNETKKVTVDSSKLKTLKSGNWDVYSVTLTVDQIKA
                     IDNCQSVGFVKKGSFNRTAYTAYRNICKASKMDGNSTYSGVRESIETFDGYMFVINSCY
                     TPSNENISLTGSWVVK"
     CDS             complement(2942..3160)
                     /locus_tag="ctg9_2"
                     /transl_table=11
                     /translation="MDKNKKLFYTIIGAISALAAATAAFLALKKHRCAEQKLIEEIDDI
                     VSEKEPEEAAKEEPQAEVTADELAEEE"
     CDS             complement(3686..4441)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 76.2;
                     E-value: 1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_3"
                     /sec_met_domain="Radical_SAM (E-value: 4.5e-30, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNAVKGFVHSIETFGSVDGPGVRFVIFLSGCAMRCQFCHNPDT
                     WKHDENTVEYTADELLNKALAYRPYWKNKGGITVSGGEPLLQIDFLLDLFKKAKKQGVN
                     TCIDTSANPFTTKEPFYSKWKELMEYTDLLLLDIKHIDNEQHKILTGQPNTNILEMARQ
                     LSDMGKPVWIRHVLVPERNDKDEYLFRLADFIRSLKNVERVEVLPYHTLGVYKWKALGY
                     DYPLEGINPPTKERVKNAEMILNGEKTRD"
     CDS             complement(4441..6678)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_4"
                     /sec_met_domain="Gly_radical (E-value: 6.5e-41, bitscore:
                     131.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.1e-271, bitscore:
                     894.5, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEWTNFAGGKWESDIDVRDFIQKNYTPYDGDQSFLEGPTEATD
                     KLWGELKELQKEERAKGGVLDMETEVVSGITAYGAAYLDKDLEKVVGLQTDKPLKRAFM
                     PYGGIKMAEQSCQMYGYTPSPKLHEIFTKYHKTHNQGVFDIYTPEMKLARHNKILTGLP
                     DTYGRGRIVGDYRRVALYGIDRLIEGKKEDFAETNRQGMRRGDFQLREEIADQIRALND
                     MKEMALSYGFDISQPAKNAAEAVQWLYFGYLAAIKTQNGAAMSVGRVSTFLDIYIERDL
                     ENGTLTESQAQELVDHFVMKCRMVKFARIESYNQLFSGDPVWATLEVAGLGIDGRSMVT
                     KNDYRFLHTLENMGPSPEPNLTVLYSSRLPENFKKYAAHISVTTSSIQYENDDVMRPVW
                     GDDYSICCCVSATQTGKEIQFFGARANLAKCLLYAINGGIDEKTKMQVGPEYTPITSEY
                     LDYDEVIKKYDTMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTDVRRTFATGIAG
                     FSHVVDSLSAIKYAKVKVIRDDDGIAVDFETEGDFPRYGNNDERADKIAVDLLKTFMAK
                     LKYCHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQNGLLA
                     SLNSVAKLPYEYALDGISNTQTINPGALGHNDDERVDNLVNVMDGYFDQGAHHLNVNVF
                     GTEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             complement(6945..7436)
                     /locus_tag="ctg9_5"
                     /transl_table=11
                     /translation="MKTDRVITAMIEYFGSDKKRIHHFLKVYSFAKTIGESENLLPDDQ
                     ELLEISAIVHDIGIKVSEEKYNSSAGKYQELEGPHEAEKLLAALGYEKTFIDKVCYLVG
                     HHHTYGNIDTLPYQILVEADFLVNLYEDDSSRSAAEQAYDKIFRTNTGKNLLKIMFLIP
                     "
     CDS             complement(7640..8164)
                     /locus_tag="ctg9_6"
                     /transl_table=11
                     /translation="MAHPIKHFRTITRHRHKVIANCARAGILRQGLIHDLSKYSPTEFI
                     PGAKYFQGTRSPNEKERELYGYSQAWMHHKGRNRHHYEYWNDYNPKTKQIENVEMPVKY
                     VIEMFCDRVAASKIYNGKNYTDGAPFTYFCRIRGKHRMHPNTEALLEKLLVMLRDEGEE
                     KTFAYIRSMKK"
     CDS             8341..9528
                     /locus_tag="ctg9_7"
                     /transl_table=11
                     /translation="MKKKIFILLLCVVLIATCILCGVTGIFGNDSQNSPKPQTPDTAVT
                     ENMTFPSTVDSLTLKVGESKLIELSSEKAKSVTKWTSSDSKIVTVDDGGRVDALKEGTA
                     LISAILKDKSKSEFQVTVAKSTMKKQQSYSTCITANLDKLENNKRNTAKNLYAIKVNRT
                     ANCVTVYTYDEKGKYTIPVRAMICSTGLDNSTITGDYTIGIKSKWLFLVGDVFGRYISG
                     ISGDYLFHSVPYYSMSEEDLELEEFNKLGEQASQGCVRLAVSDAKWVYDNCPTGTNVSI
                     YDDAENAGPLGKPGAIKITDFTNKWDPTDSNKKCPYSKATPIISGANDYTIKSGGKFYA
                     LAGVTAVDTCGNDITSNIEVFGNVITTRKGKYKVTYSVTDVLKRTSSVTITVTVQ"
     CDS             complement(10037..13597)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EKR"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg9_8"
                     /sec_met_domain="PFOR_II (E-value: 1.1e-18, bitscore: 59.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.8e-81, bitscore: 265.2,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 2e-32, bitscore: 104.7,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-13, bitscore:
                     43.0, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_7 (E-value: 7.5e-11, bitscore: 34.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 5.4e-07, bitscore: 21.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 4.6e-09, bitscore: 28.2,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00025, bitscore: 13.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.6e-20, bitscore: 64.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LARKMKTMDGNSAVAHVSYAFTDVAAIYPITPSSVMADLTDKFSA
                     QGAKNLFGRQVQVTEMQSEGGASGAVHGSLAAGALTTTYTASQGLLLMIPNMYKMAGEL
                     LPGVIHVSARALTSHALSIFGDHSDIYACRQTGYAMLCSNNPQECMDLAAVAHLAAIEG
                     RVPFLHFFDGFRTSHEIQKIEEWDYADLADMLNWDAVEAFRRRALNPEHPVTRGTAQND
                     DIFFQAREACNKYYDAVPEVVVKYMDKVNAKIGTDYKPFNYYGAEDAEHVIVAMGSVCD
                     CTEEVVDYLNAAGEKVGLLKVHLYRPFVADYMLRELPKTVKTISVLDRTKEPGSIGEPL
                     YLDVLAAINGSDFAGVKVYTGRYGLGSKDTTPGDIIAVYRNAESETPKRRFTIGIVDDV
                     TNLSLPIVENPDTTPKGTHSCKFWGLGADGTVGANKNSIKIIGDNTDMYAQGYFAYDSK
                     KSGGLTVSHLRFGKTPIKSTYYISKADFVACHNPSYVDKYDIVDDLKEGGSFLLNCPWD
                     TEELSERLPGKMKKILAERHINFYTIDGIKIGKEIGLGGRINTVLQSAFFKIADIIPAD
                     KAKELMKAAAKKSYMKKGQAIVDMNYAAIDRGMEDLKKVEIPADWANAVDNLVADKAEG
                     NGALVEYVNEILKPVNAYKGNKLPVSTFMDHVDGTAPNGSAAYEKRGIAVDVPEWNPEN
                     CIQCNRCAIVCPHAVIRPVAMTADELAKAPEGTKSLPMMGLKDLNFVMTVSTLDCTGCG
                     ACAQVCPGKKGAKALTMQSIDSQRPKQAVFDYALTLEDKPEVHEKFKFTTVKGSQFKQP
                     LLEFSGACAGCGETPYAKLVTQLFGDRMFIANATGCSSIWGASAPATPYTKNKKGYGPA
                     WQNSLFEDNAEFGLGMALGQKAIRNRLIEYVEGIQKDTDSADLKTACQNYLDTVTDSTS
                     SRPATDALIAELEKNTEDAKVGELVKKTLVDKDELAKKSMWIFGGDGWAYDIGFGGLDH
                     VIASGENVNILVFDTEVYSNTGGQASKATPVGSVAQFAAAGKAVKKKDLAAIAMSYGYV
                     YVAQCAMGADNNQVLKAMVEAESYNGPSLVICYAPCINHGIKGGMGIAQLEEKKAVEAG
                     YWNIFRYDPRLADEGKNPFMLDGKAPSASYRDFIMGEVRYNSLTRSFPERAEKLFEKAE
                     KVAADKYAHLEKLASLPDAE"
     CDS             complement(13985..14722)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg9_9"
                     /sec_met_domain="HAD_2 (E-value: 7.8e-38, bitscore: 122.3,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LYHNFVAITTDLSFFVKYAIIYRLKSEKRGGFMFKGAVFDMDGLM
                     IDSERLVYSIWQEMLDEDGKEFNLDIFKKTIGLRSEDSYEYYKSVYGDDFDYPAYKAES
                     RIRYFKRIEKNGVPVKKGLYEIFDYLKSVGCKISLATSTSSQTALKIMKKINLYDKFDA
                     FVCGDDVKNGKPDPEVFLIAAKKLGLEPVDCVAFEDSINGIKSAHSAGMTTVMVPDLSE
                     PTDEIKPMIDFLCTDLSEAIKHL"
     CDS             14772..16136
                     /locus_tag="ctg9_10"
                     /transl_table=11
                     /translation="MATSIYAKPIKAKTILKFTLPTVLMMVFMSLYTVVDGIVVANCVG
                     SDALSAINIVYPFTLVFMAVGLMFSTGSNAIIAKKMGEGKQEEANRLMSGVAITATVIS
                     VIIAVLFTIFAEPMYMMFGSNEKILPYCIDYGSVMIPYGFVMCWQMLNQSYLVTADKPH
                     IMLVFSILSGCTNIVLDILFMAVWDFGIIGAGLGTIIGMAVGAIPLLLFFNKKQTLHFG
                     KPEFKVSEILFAMANGSSEAVTNLSTAVTTALFNIQMMHFAGAKGVAAISAILYIHFIF
                     TAVSFGFTSGVSPVISFNYGAQNHEKLQKLFKLCIKITLIISVAMITASEFFAEPLVGI
                     FSAGNEKIQQIALSGFRIFAINYLLCGMNIFASGLFTALNNGKISAVISVARTLVFECA
                     AMLILPMFIGINGVWSALPVAELCAVAISVTFIIANAKKYHLVGVPPHPVRADSL"
ORIGIN
        1 cgcttccgca accgcattct acatatgttc tcactcaaat cagcaaaaaa caatacaaaa
       61 caagcggcag tttaaacaac caccacttgt caatttcaat tattctgttt taatgctacc
      121 ccaactattg acatagagcc caaatacttt gaacaactta attacacaca taaaaactcc
      181 ccgcacaaaa ctgtacgggg agaaaataag tttattttgt tttaagtaat cggattactt
      241 tactacccag ctacctgtaa gtgaaatgtt ttcattgctt ggtgtgtagc aagagttgat
      301 tacgaacata tagccgtcaa atgtttcgat tgattcacga acaccgctgt atgttgaatt
      361 gccgtccatc ttgcttgcct tacagatatt tctgtatgct gtgtaagctg ttctgttgaa
      421 tgaacccttc tttacaaagc ctacgctctg gcagttatca attgccttaa tctggtcaac
      481 tgtaagtgtt acgctgtaaa catcccagtt acctgactta agtgtcttga gttttgaaga
      541 atcaactgtt accttcttgg tttcgtttac cttcttcata tcaattctct cagcttttgt
      601 gtaaacattg tcattgctat aatagagctg tacacctgta tcccagtttg catagttctt
      661 tacacccttt ggtgctgcaa agtaaagtgt tactgtgtca tctttgccct gtgtataaac
      721 atcctttgtt tcccattcac ctgtatatgt agctactgat gatgatttag ctgtcatacc
      781 cttgattacg aagagctgac cgtcaagttc tgaaagtgtt cttgcctttg agttgtagtt
      841 gccgtcaaat gtatttgtct ttgcgaaaag tacattcttg aggattgctg ttctgtttac
      901 tgcatctgtc ttgttaaagc cgacatactt tgcattttct actgctgatg ctgttgcctt
      961 atcaagtgtg attgcataga tgtaccatct gcctgttttg attgtcatat tgccgttgag
     1021 agatgatacc tttgttgtgt cgcctgtgtt gatcattgaa agctttgtca ttgaatcgaa
     1081 agctgttgtg ttaccataat aaagatcaac attgtcccat gtagaatatg atgttgctgc
     1141 aagcggagct gctgctctta ctgttacaaa gtcgcttacc caatagccta cgaatgatac
     1201 tgatgatgtt gcaccgtaag ctgaatctct gataacgaat gtcttgccgt caagagctgc
     1261 aactgtgttt gctgttgtac cgtacttagc tgtgtaagta tctacacctg ctttaagaac
     1321 atttgaaccg cttacgagag ttgttctgtt tacgccgtta gctgttgcaa aaccgacaaa
     1381 ctttgatgaa ttgattgctg ctgcctgatc ctttgaaatc ttgagttcgt atactgtcca
     1441 gccgtttgtt gtgagaagtg tgtttgaacc aacttctgtt gtgtaatact tctcgcttgt
     1501 tgctgtcatt gaaagctttg ttgacttgtc aactgactgt gtgttgccgt agaagagtac
     1561 aggcttgctc cagttgtatc ttgatgcctg gcttgtagga gccgcaaact tgattgttgc
     1621 accgtcacct gaaggtgttg ttgtcggctc tgttgcaggc tgagtaggct ttgttgcggg
     1681 agctgttgtt ggctgtgttg ctgttgttgg ctgtgttaca gttgtaggct gaggagctgt
     1741 tgttggctct tcgccctgaa cgagaactgc ctttgcagta aatgcagcac cttctacttt
     1801 gttagcacta tcgtaaatat aatcgatgtc cttcttttca ctttcgaaga aatcatcata
     1861 tgattcagcc tctgtacctg taagataatc aacattaaga tttactgttg tgtcaccgct
     1921 gcctacaaca tcaaatgtaa atgtgcaata aacattctct gacttgaagt tgaaaagatc
     1981 aaggcttgag cagttgaagt aaacctgatt tgtaatgctt gtattccaaa cgatgctgct
     2041 ctggaataca gggaaaacct ttttctttgt atttgttgtt gttgttgatg caagcttgag
     2101 aaccttgctg tcgtatgtaa ggctgctctg tgtatcaacg atcatgtggt ctgccttgag
     2161 aaggtaagta acaacaacct gctctgtctg tgcattgtaa tcatacgaaa caggatctgt
     2221 cacatttgat gtaacattga tcttgttgcc tgcacttgtt tcttcgcttg tttcggcagc
     2281 acttgctgag aaaggcagag ctgtgaacat gcacagcacc atcattaccg caagaaccac
     2341 agaaagcttt ttctgaattt ttttcatact tgctgctcct ttaataaaat aaaattaccg
     2401 ttcgccacag ttttgtggca atacttctaa gcttcggaaa ctttaacagt acaaaatttc
     2461 cgaggacatt taaattatag cacatttaag ttgttcgggc aatgaatctg ttattctttt
     2521 agcgaaaatt ttttgcccta aaatatgtgc aaattaacgg taagtttgct attatataca
     2581 aattcattgt cagattattg tggatattgt ctaatccata ttccacagtt cagaaataac
     2641 tgataataat actatcgtat ttaattttta caacaattgt tttgtaacaa aaaagtctgc
     2701 gtcaagagca atttcgatgg ggctgtgaca aaacagccta acaaaacaaa aatgcatcag
     2761 accttttcgg acatctgatg cattttcttt tttaaactgt tttcttgaat agattgtggt
     2821 ggcacaccgc cgacatcatt atctgtttta actttcaatt cttaattgaa agcaccgctc
     2881 gggtatttaa ctttcgcaca tacaaatact gctacccgaa tttggtgcaa caacttgttg
     2941 cttattcttc ctcagcaagc tcatcggctg taacttctgc ctgcggttct tcctttgcag
     3001 cctcctcagg ctctttttcg gaaacaatat cgtcaatttc ctcaataagc ttctgttctg
     3061 cgcatctgtg cttttttaaa gcgagaaatg ctgctgtggc agccgcaagt gcagagattg
     3121 caccgatgat tgtgtagaat aattttttgt ttttatccat tccggcacct ctttcagtat
     3181 taatataaat cataaatcag cggaaaaacc gtatttttct acttattgct attttatatc
     3241 atttttacaa atttttcaat agacaactga taatctttgc acaaatggct gtcagtgtgt
     3301 tatattctct ttttacgctc tgcaagggca aaaagcactc cgcccgaaat tacaacaagc
     3361 atcataacag ccgttgctgt cactcctgtc tgaacactgc cgtttttatc aggctgtgaa
     3421 ggagtgctgt ccgatgttgc ggcaccgcct gttgccgaag tcggatttgc agaggttgta
     3481 ccgacagttg caggctcacc cgtcggagca gtcggttctt ccgactgtga cgatttctca
     3541 acaaggacgg cttaaaaatc tttgaataca cctttgattc atcaattttg ctgaagaaga
     3601 aacaacaaaa gcagaataac aaataaaaat caaaacaaaa acggcagtac caaaaaaatc
     3661 ggtactgccg tttttatata agaaattaat ctcttgtttt ttcgccgtta agaatcattt
     3721 ccgcattctt aacacgctct tttgtcgggg gattaatgcc ctcgagagga tagtcataac
     3781 cgagagcctt ccacttgtac acaccgaggg tgtgatacgg aagcacctct acacgctcaa
     3841 cattcttgag cgaacggata aagtcggcaa gtctgaaaag atactcgtcc ttatcatttc
     3901 tttcaggcac aagaacatgt cttatccata cgggcttgcc catatcggaa agctgtcttg
     3961 ccatttcaag aatattggtg tttggctgtc ctgtaaggat tttgtgctgt tcgttgtcga
     4021 tatgctttat atcaagcaac agcaaatccg tatattccat tagctctttc cactttgaat
     4081 agaacggctc tttggttgta aacgggttgg cgcttgtgtc aatacaggta ttaacgcctt
     4141 gctttttagc cttcttgaac aaatcaagca aaaagtcaat ctgtaaaagc ggctcacctc
     4201 cgcttactgt gataccgccc ttatttttcc aataggggcg gtatgcaagc gctttattaa
     4261 gcaactcgtc ggcggtgtat tccacggtgt tttcatcgtg tttccaggtg tcgggattgt
     4321 ggcagaactg gcaacgcatt gcgcaaccgc tcagaaaaat cacaaatctc acgcctggac
     4381 cgtcaacaga gccaaaagtt tctattgagt gtacaaagcc tttaacagcg ttgtccgaca
     4441 ttacattctg tcgtggcagg ttctggcaat aacatccagc tgctgctctc ttgtaaggtc
     4501 gatgaactta acagcataac ccgatacacg gattgtgaag ttagcatact cttccttctc
     4561 aggatgctcc atagcgtcaa tgagtttttc tgtaccgaat acatttacat tgaggtggtg
     4621 tgcgccctga tcaaagtagc cgtccataac atttacgagg ttgtcaacac gctcgtcgtc
     4681 gttgtgtccg agagcacccg ggttgattgt ctgagtattt gaaataccgt caagagcgta
     4741 ctcgtaagga agcttagcaa cagagttaag tgaagcaaga agaccgttct gctctgcacc
     4801 gtagcttggg ttagcacccg gtgaaagcgg ctcgcctgct tttctgccgt caggaagtga
     4861 acctgtagcc ttaccgtaaa caacatttga tgtgattgta aggatagaag ttgtaggctc
     4921 tgaatctctg tatgtgtggc aatacttaag cttagccata aatgtcttaa gaagatcaac
     4981 ggcaatctta tctgctctct cgtcattgtt accgtatctt gggaagtcac cctctgtttc
     5041 aaagtcaaca gcaatgccgt catcgtcacg gataacctta accttagcgt acttaatagc
     5101 gctgagtgag tcaacaacat gtgagaagcc tgcaatacct gttgcaaatg ttcttcttac
     5161 atctgtatcg ataagagcca tttctgctgc ctcatagtag tacttatcat gcatgtagtg
     5221 aatcatgtta agtgtgccta catagaggtg agcaagccaa tccatcattg tgtcatactt
     5281 cttgataact tcgtcataat caaggtactc tgatgtgata ggtgtatatt caggaccaac
     5341 ctgcatcttt gtcttttcat caataccgcc gttgatagcg tagagaaggc acttagcaag
     5401 gttagctctt gcgccgaaga actggatttc cttacctgtc tgtgttgcgg atacgcagca
     5461 gcagattgag taatcatcgc cccatacagg acgcattaca tcatcgttct cgtactgaat
     5521 tgagcttgtt gtaactgaaa tatgagcagc atacttcttg aagttctcgg gaagtcttga
     5581 agaataaaga actgtgaggt ttggctcagg tgaaggtccc atattctcaa gtgtgtggag
     5641 gaaacggtag tcgttctttg taaccattga acggccgtca atgccaagac ctgcaacttc
     5701 gagtgtagcc catacagggt cgcccgagaa gagctggttg taagactcaa ttcttgcaaa
     5761 cttaaccata cggcacttca taacaaagtg gtcaacgagt tcctgagcct gtgattctgt
     5821 aagtgtaccg ttctcaaggt cacgctcgat gtagatgtcg aggaatgttg atacacgacc
     5881 aacgctcatt gcagcgccgt tctgagtctt gatagcagca agatagccaa agtagagcca
     5941 ctgaactgcc tctgcagcgt tcttagcagg ctgtgaaata tcaaagccgt aagaaagtgc
     6001 catttccttc atatcgttaa gagcacgaat ctgatcagcg atttcttcac gaagctggaa
     6061 gtcgcctctt ctcataccct gacggtttgt ttctgcaaag tcctctttct tgccttcgat
     6121 aagacggtca ataccgtaaa gagcaactct tctgtagtca ccgacgattc tgcctctgcc
     6181 gtatgtgtcg ggaagacctg taagaatctt gttgtgacgg gcaagcttca tctcaggagt
     6241 gtagatatcg aatacaccct ggttgtgagt cttgtgatat tttgtaaaga tttcgtggag
     6301 tttagggctt ggagtgtagc catacatctg gcatgactgc tcagccattt taataccgcc
     6361 gtaaggcata aatgcacgct tgagaggctt gtctgtctga agacctacaa ccttttcaag
     6421 gtctttatca agatatgcag cgccgtaagc tgtgatgccg cttacaacct cagtttccat
     6481 atcaagaacg ccgcccttgg ctctttcttc cttctggagt tccttgagct cgccccagag
     6541 cttgtctgta gcttctgtag gaccttcaag gaaagactgg tcgccgtcat aaggtgtgta
     6601 gtttttctga atgaagtctc tgacatcaat gtcggactcc catttgccac ctgcaaaatt
     6661 tgtccattct tctctcatta ctgtaaaacc tccgataatg ataattaata ctgaattttg
     6721 tatatgacac aaaaaaatgc cgactcaatt ccaagcagac gcccggtaag gtcagctcct
     6781 tgaaaaaatc gtcatacatc cttgtattct gtcatttatt cacttttata atcatataac
     6841 caacaccatt aaaataacac tttttaaggg cgttgtcaag cattttgaga tactttttac
     6901 accacttttt cacactcaaa gcgctatggt aaatgagtac aattttaggg tatgaggaac
     6961 attattttca gcagattttt tcctgtattt gtgcggaata ttttgtcata tgcctgctct
     7021 gctgcactgc ggcttgaatc gtcctcgtaa aggttcacaa ggaagtctgc ctctaccaaa
     7081 atttggtacg gcaaagtatc aatatttcca taggtgtgat ggtgtcccac aaggtaacaa
     7141 accttgtcaa taaatgtttt ttcgtagccg agagcagcaa gcaacttttc agcctcgtga
     7201 ggaccttcaa gttcctgata ctttcctgca gacgaattgt acttttcttc gctcaccttt
     7261 atgccgatgt cgtgaacgat tgcggagatt tcaagaagct cctgatcgtc gggcaaaaga
     7321 ttttcacttt caccgattgt ctttgcgaat gaataaacct tgagaaaatg gtgaattctt
     7381 ttcttgtcac ttccaaaata ttcaatcata gcagttataa ccctgtcggt tttcatatta
     7441 tcactcctta cggcgagccg ccgtacacta ttcgtgtaga tagttttttg tttgtgcaat
     7501 tctgtagggg tagccttgcg accgccgcct gtggcggata aagggagcaa agcgctgtct
     7561 gaaataacga gcaataggca gtacatttat gtacaaagct ttgcgactat atttcagacg
     7621 ggaggattcg cacaaacaat cactttttca tacttcttat atatgcaaat gtcttttctt
     7681 caccctcatc tctcagcata accaataatt tttcaagcaa agcctcggtg ttggggtgca
     7741 tacggtgttt gcctctgatt ctgcaaaaat atgtaaacgg agcgccgtcc gtgtaatttt
     7801 tgccgttgta gattttgctt gcggcaactc ggtcgcagaa catttcgata acatatttta
     7861 caggcatttc aacattttca atctgctttg tctttgggtt gtaatcgttc cagtattcgt
     7921 aatggtgacg gtttctgccc ttgtgatgca tccacgcctg tgaatagccg tacagctctc
     7981 tttccttttc attgggactt ctcgtgccct gaaaatactt tgcacccgga ataaattctg
     8041 taggcgaata ctttgacaaa tcgtgtatta atccctgtct gagaattcct gcccttgcac
     8101 agttggcaat taccttgtgc ctgtgacggg ttattgttct gaaatgttta atcggatgtg
     8161 ccataattat caccatgaat tgttagtttg gaaaatacaa aacattctcc gactgtcatt
     8221 ttaccacatt tctcgccgat ttaaaatagc acttgcaaga ttgtcgaaaa aaagttataa
     8281 tatacaaagg ttaaaatttt gtaaccattt aatgttaaat tctataagga taggtaatct
     8341 atgaaaaaga aaattttcat tcttttactt tgtgttgtcc tcattgcaac ctgcatatta
     8401 tgcggtgtga cgggaatttt cggaaatgat tctcaaaatt ctccaaaacc gcagacgccc
     8461 gatacggcag taaccgaaaa tatgacattt ccgagcacgg tcgattcgct cacattaaaa
     8521 gtaggcgaat caaagcttat tgaactgtca tccgaaaaag caaaatccgt taccaaatgg
     8581 acaagctcgg acagtaaaat tgttaccgtt gatgacggcg gaagggttga cgctctcaaa
     8641 gagggtacgg ctctgatttc tgccatttta aaagacaaat caaagtcgga atttcaggtt
     8701 acggtggcaa aatcaaccat gaaaaaacag caaagctact caacctgtat aacggcaaat
     8761 cttgacaagc ttgaaaacaa taagcgtaac acggcaaaaa acctgtacgc aatcaaggtc
     8821 aaccgcacgg caaactgcgt gacggtttac acatatgacg aaaagggcaa gtacacaatt
     8881 cccgtaaggg cgatgatttg ctctacaggt cttgacaatt cgacaatcac aggtgactat
     8941 acaatcggaa tcaagtccaa atggcttttc cttgtgggcg atgttttcgg aagatacatc
     9001 agcggaattt cgggcgatta tcttttccac tccgttccct actactcaat gagcgaagaa
     9061 gatttggagc ttgaggaatt caacaagctt ggcgaacagg catcacaagg atgcgtaaga
     9121 cttgcggttt cggatgcaaa gtgggtttat gacaactgcc ccacaggcac gaatgtaagc
     9181 atatatgacg acgcagaaaa tgcaggccct ctcggaaaac cgggtgcaat caaaatcacc
     9241 gatttcacca acaaatggga tccgacagac agcaataaaa aatgcccgta ttccaaagca
     9301 acaccaataa tcagcggcgc aaacgattac acaatcaaaa gcggcggcaa attttacgcc
     9361 cttgcaggag taacagccgt tgacacctgc ggcaacgaca taacttcgaa tatcgaagtt
     9421 ttcggcaatg tgataaccac ccgaaaaggc aagtacaagg taacatattc agtcactgat
     9481 gtgcttaaaa gaacatcaag cgtaacgatt acggtaacgg tgcaataaac acggtgcgcc
     9541 actgttctcc gagcggagct tttaaattga aagtggaaaa ttgaaaatgg aaaatgaatg
     9601 tcgggaagac ggcttgcaaa atgcaaaaca tcgtcttccc gactgttttt tatatatgaa
     9661 agttgttgtt tatctgttgg ggcggatatc attcgcccac aagcaacggc acagactata
     9721 tattaataca aattttataa atgctgcaaa gcaactgtaa taatgtatgg gcgaaccgtt
     9781 accatgttgc acttgacacc gtgttcgccc atacagattt gtacaaacat tgcataccta
     9841 cactcgggca tattcactct ctcattaaca agactgtctt cccgaaagga ctgcggtggc
     9901 acaccgctga ccataatttt caattttcca ttttacattt tcaattaaaa aagaatctcc
     9961 cgaacacggc aaatgccata ttcgggagaa ttttttattt attcacatat tcactttgta
    10021 caagctttag ccaaaattac tcggcatcgg gaaggcttgc aagcttttca aggtgagcat
    10081 acttatcagc agcaaccttt tcagcctttt caaagagttt ttctgctctt tcggggaatg
    10141 aacgagtgag tgagttataa cgaacttcgc ccatgatgaa gtcacgatat gatgcagaag
    10201 gagctttacc gtcaagcatg aacggattct ttccttcgtc tgcaagacga ggatcgtaac
    10261 ggaagatgtt ccagtaacct gcctcaacag cctttttctc ctcaagctga gcaatgccca
    10321 tgccaccctt gataccgtgg ttgatacacg gagcgtagca gattacgagt gacggaccgt
    10381 tgtagctttc agcctcaacc atagccttga gaacctgatt gttgtcagca cccatagcgc
    10441 actgtgcaac ataaacatag ccgtagctca ttgcaatagc ggcgaggtct ttcttcttaa
    10501 cagccttacc tgcggcggca aactgtgcaa ccgaacctac aggagtagcc tttgaagcct
    10561 gaccgcctgt gttagaataa acctcggtat cgaatacgag gatattaaca ttttcgcctg
    10621 atgcgattac atggtcaaga ccgccgaagc cgatatcgta agcccagccg tcaccgccga
    10681 agatccacat tgacttctta gcaagttcgt ccttgtcaac gagtgttttc ttaacaagtt
    10741 cgccaacctt tgcatcctct gtgttctttt cgagttcagc gataagagcg tctgttgcag
    10801 gacggcttga agttgaatct gttactgtgt cgagatagtt ctgacaagct gtcttgaggt
    10861 cagcgctgtc tgtatccttc tgaataccct caacatactc gataagtctg ttgcggatag
    10921 ccttctgacc gagagccata ccaagaccaa actctgcgtt atcttcaaag agtgagttct
    10981 gccaagcagg accgtaaccc ttcttattct ttgtataagg tgttgcagga gcagatgcac
    11041 cccaaattga tgaacagcct gttgcgttag cgataaacat tctgtcaccg aaaagctgtg
    11101 taacaagctt tgcatacggt gtttcaccgc agcctgcgca agcgcctgag aattcaagca
    11161 acggctgttt gaactgactg cccttaactg tagtgaactt gaacttctcg tgaacttcag
    11221 gcttatcttc aagtgtgaga gcgtagtcaa atactgcctg cttaggacgc tgtgagtcga
    11281 ttgactgcat tgtgagagcc ttagcgccct tcttacccgg acaaacctga gcacaagcac
    11341 cgcaacccgt acagtcgagt gttgaaactg tcattacaaa attgaggtcc ttaagtccca
    11401 tcatcgggag gctctttgta ccctcgggag cttttgcaag ctcatcggct gtcatggcaa
    11461 caggacggat tacagcgtga ggacatacga ttgcacatct gttacactga atacagtttt
    11521 caggattcca ttcgggaaca tcaactgcga tacctctctt ttcataagcg gcagaaccgt
    11581 taggagcagt accgtcaaca tgatccataa atgttgaaac agggagtttg ttacccttat
    11641 acgcatttac aggcttgagg atttcgttta catactcaac gagagcgccg ttaccctctg
    11701 ccttgtcggc aactaaatta tcaacagcat tagcccaatc agcaggaatt tcaaccttct
    11761 tgaggtcttc cataccacgg tcgatagcgg cgtagttcat atctacgata gcctgacctt
    11821 tcttcatgta tgacttctta gcggcagcct tcataagctc cttagccttg tcggcaggaa
    11881 tgatatctgc aatcttgaag aaggctgact gaagaaccgt gttgatacga ccgccaagac
    11941 cgatttcctt accgatcttg ataccgtcaa ttgtgtagaa gttgatgtgt ctttcagcga
    12001 gaatcttctt catcttaccc gggagacgct cggaaagctc ttctgtatcc cacgggcagt
    12061 taagaaggaa tgaaccgcct tctttaaggt catcaacaat atcgtacttg tcaacataag
    12121 acggattgtg acaggcaaca aagtctgcct ttgaaatgta gtatgttgac ttaatgggag
    12181 ttttaccgaa acgaaggtga gaaactgtaa gaccgcctga cttctttgag tcatatgcaa
    12241 agtagccctg agcgtacata tcggtgttat cgccgataat cttgattgag ttcttgttag
    12301 caccgacagt accgtcagca ccaagacccc agaacttaca gctgtgtgta cccttcggag
    12361 ttgtatcggg attttcaaca atcggaagtg agaggtttgt aacatcatca acaatgccga
    12421 ttgtaaatct tctcttaggt gtttcgcttt cagcgtttct gtaaacagcg atgatgtcgc
    12481 cgggtgttgt atcctttgag ccaagaccgt atctgcctgt gtaaaccttt acacctgcaa
    12541 agtccgaacc gttgatagcg gcgagaacat caagataaag aggttcgccg attgaaccgg
    12601 gttcctttgt tctgtcaaga acagagattg tcttaacagt cttaggaagc tctctgagca
    12661 tatagtcggc aacgaaaggt ctgtaaaggt gaactttaag aagaccgacc ttttcgcctg
    12721 cggcattgag gtaatcgaca acttcttccg tacagtcgca gacagaaccc atagcaacga
    12781 taacatgctc tgcatcctct gcaccgtagt agttgaacgg cttgtagtca gtgccgattt
    12841 tagcattaac cttgtccatg tacttaacaa caacttcggg aactgcgtca taatacttgt
    12901 tacaagcttc tcttgcctgg aagaagatat cgtcgttctg agcagtacct cttgttacag
    12961 gatgctcagg gttaagagca cgacgacgga aagcctcaac tgcatcccag ttaagcatat
    13021 cggcgaggtc tgcgtaatcc cactcctcaa tcttctgaat ttcgtgagaa gttctgaaac
    13081 cgtcaaagaa atgaaggaaa ggaactctgc cttcaatagc tgcaaggtga gcaacagcgg
    13141 caaggtccat acattcctga ggattgtttg aacaaagcat agcataacct gtctgacggc
    13201 aagcgtagat atctgagtgg tcaccaaaaa tagaaagtgc gtggcttgtg agcgcacggg
    13261 ctgatacatg aataacgccc ggaaggagct cgcctgccat cttgtacata ttcggaatca
    13321 taaggagcag gccctgtgat gctgtgtaag ttgtggtcaa agcacctgct gcgagtgagc
    13381 cgtgaacagc acctgatgcg ccgccctccg actgcatttc cgttacctga acctgtctgc
    13441 cgaaaaggtt cttggcaccc tgtgccgaga acttgtcggt aaggtcagcc attacggaag
    13501 aaggtgtaat aggatagata gccgcaacat cggtaaacgc ataagaaaca tgagctactg
    13561 cgctgttacc atccatagtt ttcatttttc ttgccaatgg aatcgtcctc ctttttaatc
    13621 aaagcggcaa aggaaatgat gccgcataaa ttttcgatac ccgttaatta cgcaccgtaa
    13681 atcaacaagc ggtacggata ctttgtatca tcttaaattt tatcacttaa acaccgattt
    13741 gtaaagtgtt ttacacaaga aattcaaagc aggatatata tttttgtttc gttttttaca
    13801 aaaaagtttt ttatatttac ttgttcctgt caaaatactt tgttgttgat tttttaaaaa
    13861 tcaacaacaa aggttttggc tatttgtaca aacggttgca atgtttcgct cggacataat
    13921 ttgttttttg acattacaaa ctatctacac gaattgggaa cggcggctcg ccgtaatttt
    13981 caatttataa atgctttatc gcttcgctta aatccgtaca caaaaaatct atcatcggtt
    14041 taatttcgtc tgtcggctct gacaaatcgg gaaccataac cgtggtcata cctgcggaat
    14101 gtgcagattt tatgccgtta atgctgtcct caaacgcaac gcagtccacc ggctcaagac
    14161 cgagcttctt tgcggcaatc aaaaaaacct cgggatcggg tttgccgttt ttaacatcat
    14221 caccgcacac gaatgcgtca aatttatcat agagattgat tttcttcata atcttcaaag
    14281 ccgtttgtga cgaggttgaa gttgcaagcg aaattttaca accgactgat tttaaataat
    14341 caaaaatttc gtacaagccc ttttttacag gcacaccgtt cttttcgata cgcttaaaat
    14401 agcggattct cgactccgcc ttgtaagcag gatagtcaaa atcatcgccg taaaccgact
    14461 tgtaatattc gtaggaatcc tcactgcgaa gtccgattgt ctttttgaaa atgtcaagat
    14521 taaactcttt gccgtcctca tcaagcattt cctgccagat tgaataaaca agcctttcgc
    14581 tgtcaatcat aagcccgtcc atatcaaaaa ctgcgccctt aaacataaaa ccgccccttt
    14641 tttcgctttt aagtctgtat ataatagcat attttacaaa aaaagacaaa tcggttgtaa
    14701 ttgcgacaaa gttatgatac aatcgtttga atggtctgtg aaaaatataa atttgagggt
    14761 gaggaaattt tatggcaaca tcaatttatg caaaacctat taaggcaaaa acgattctga
    14821 agttcacttt gccaaccgtt cttatgatgg tttttatgtc actttacaca gttgttgacg
    14881 gaatcgttgt tgcgaactgt gtcggaagtg acgcattgtc cgcaatcaat attgtatatc
    14941 cgttcacgct cgtatttatg gctgtgggct taatgttttc aacaggctca aatgctataa
    15001 tcgcaaagaa aatgggagaa ggcaaacagg aggaagcaaa ccgacttatg tccggtgttg
    15061 caatcacggc aacggtcatt tctgttatca ttgctgtgct gttcacaatt tttgccgaac
    15121 ctatgtacat gatgttcggc tcaaacgaaa aaattctccc ctactgcatt gactacggca
    15181 gcgttatgat tccgtatggc tttgtaatgt gctggcagat gctcaaccaa tcgtaccttg
    15241 taacagcaga caagccacat atcatgcttg ttttctcgat actgtcgggt tgcacaaaca
    15301 ttgtgcttga cattcttttt atggctgtgt gggattttgg aataatcggt gcaggactcg
    15361 gcacaatcat cggaatggct gtgggtgcaa ttccgctttt gctctttttc aacaaaaagc
    15421 agactctgca ctttggcaag cctgaattca aggtaagtga aatcctcttt gctatggcaa
    15481 acggctcgtc agaagctgtg acaaatcttt caacagccgt gacaacagcg ctgttcaaca
    15541 ttcagatgat gcactttgca ggcgcaaaag gcgttgcggc tataagtgct attttgtaca
    15601 ttcactttat tttcactgcg gtttcgtttg gattcacttc gggagtttca cccgtcatca
    15661 gctttaacta cggcgcacaa aatcacgaaa aactgcaaaa gctgttcaaa ttatgcataa
    15721 aaatcacgct gataatttcg gttgcaatga ttacggcatc tgaatttttt gcagaaccgc
    15781 ttgtcggaat tttctcggca ggcaacgaaa aaattcagca gattgcactc agcggattca
    15841 gaatttttgc aataaattat ctgttgtgcg gaatgaatat tttcgcatcg ggacttttca
    15901 ccgcactcaa caacggcaag atttcagccg taatttcagt tgcaagaaca cttgttttcg
    15961 agtgtgccgc aatgctgatt ttgccgatgt ttataggcat aaacggtgta tggtcggcat
    16021 tgcccgttgc agaattgtgt gccgttgcaa tttccgtaac atttataatt gccaatgcaa
    16081 aaaaatacca tctggtcggt gtaccaccgc accccgttcg tgcagacagt ttgtgatatc
    16141 aaaaacatat tatgcccaag tgtagcattg taaccatttg tacaaataaa cgcaaaaaat
    16201 ccgagcatca aaacaatgct cggataattt tttacaacaa ttaaagttca attaaaatcg
    16261 aaatcagatt gcacgaactc tgattacgcc gtcaactgct gcgatttttg caaggtcatc
    16321 tgcaccggcg cctgcaacat caataattgt gtaagcatag tcgccacggc tctttgaaag
    16381 catattttca acattgccgc tgatctgtgt gagaaccttc ttgagaagct cgggaacatt
    16441 cttgtgagca acgcagaaac gggtatcgtc agcatttgtt cttgcaagtg aaattgcagg
    16501 atagtttacg gagttgatga tgttaccgtt ctcgagatac tccttaacct gatcacaagc
    16561 cataacagca caattttctt cactttcggg agttgatgca ccgaggtgtg ggaggcagat
    16621 aatattctct tcaccgagaa tatcgtctgt tccgaagtct gtaacatact tagcaacc
//
