LOCUS       c00223_gnlPro..        24383 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PFBDDIFG_223.
ACCESSION   c00223_gnlPro..
VERSION     c00223_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 21:56:13
            Original ID  :: gnl|Prokka|PFBDDIFG_223
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 24383
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24383
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9060:14383]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9061..14383
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24383
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24383
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(114..1193)
                     /locus_tag="ctg223_1"
                     /transl_table=11
                     /translation="MKTTLLIMAAGIGSRFGTGIKQLEPVDYAFQDINDIPGTLPEGRT
                     KPWGTGQAVLAAKKVIKTPFIVINADDYYGKEGFKAVHEYLVNGGKSCMAGFVLKNTLS
                     DNGGVTRGICKMDEDYNLTEVVETKNIVKTAAVAEAEGMAVDVDSLVSMNMWGLTPDFL
                     TTLEEGFKEFFEKEVPGNPLKAEYLIPIFIGELLEHGKISVKVLKTNDTWYQKFKESVF
                     FRKLFLLFFVTSMILFRTLLNRNLWMNPLSKVMGGWGIWETVNGEQKLTTECIENVIIM
                     VPFSSVVMWTFKEKTGNGWKKILWYSGKIAFIFSVSIEMLQLLLRLGTFQLSDIFYNTV
                     GGMLGGLVYYVTMKARKHL"
     CDS             1540..2916
                     /locus_tag="ctg223_2"
                     /transl_table=11
                     /translation="MNTTANLGKAPVRTLVLQLAIPSMTAQFVNVLYSIIDRMYIGHIS
                     QNGALALAGAGVCGPIVTFLTSFGTLVGIGGSITMGIRMGEKNHKKAEQVLANSFLVLS
                     IFSVLLTISFLLLKDKLLMWFGASGATFPFANTYLTIYTTSTFFALMATGLNYFINCQG
                     FPLVGMFTVLIGAGCNILLDPIFIFGFHMGISGAAIATVISQILSCIFAMTFLLGKKVP
                     VKITFGQYNLKVIKKILSLGFSPFLILATDSLILIFMNTVLQKYGGASQGDILITCATI
                     AQSYLLLITSPMIGISGGTQAILSYNYGARCVNRVKDAERNILGVMLIFTTIMFLLSRF
                     IPRYFVLLFTTDPQYIRFSVWTIRTYTLMIIPLSFQYVFVDGLTALECPKTGLALSVTR
                     KSLFVISAAVLPSFFGAKAAFFAEPVADGISSVLSTVVFLLLINRHLDKRCQMDKEAIL
                     "
     CDS             3282..4064
                     /locus_tag="ctg223_3"
                     /transl_table=11
                     /translation="MYHQLYNTLETYEYTGNFLNLLSSDIMDEKGNDLSADTNGKLYVS
                     LSAKKGIVIKDEQTTAKHDISGNLTMHPSGAWGLAYSYSNDTEKITFQDGNILKEPWIL
                     TSMDDDEVRTGIFKQVSLIEIGNEHIMVYGCLVGDDAPYKIAVYDQDGNQQLLLGRDPS
                     DDSASFGYITGVAETANGYIATDGNARILYFWSKDGTLLGKIQCSDIFGTRYPWLEDIK
                     VADDGSAIFPVMLSALICIQTPISTSSSTKSILVRVAS"
     CDS             complement(4678..5754)
                     /locus_tag="ctg223_4"
                     /transl_table=11
                     /translation="MSELSFEQMLEDSVKTIRNGEIVQGTVIDVKEDEIILNIGYKADG
                     IITKNEYSNDASLVLTDAVHVGDTMEAKVLKVNDGEGQVTLTYKRLAAEKGNKRLEEAF
                     ENQEVLKAPVTQVLDGGLCVNVDEARVFIPASLVSDTYEKDLSKYADQEIEFVITEFNP
                     RRRRIIGNRKQLLLAEKAEKQKELMERIHVGDTVEGTVKNVTDFGAFIDLGGADGLLHI
                     SEMSWGRVENPKKVFTVGDKVKVLIKEINGEKIALSLKFPEANPWLTAAEDFAVGNVVK
                     GKVARMTDFGAFVELAPGVDALLHVSQISREHVAKPADVLSIGQEIEAKVVDFNGEDKK
                     ISLSMKALEAPAEEAAEE"
     CDS             complement(5735..6613)
                     /locus_tag="ctg223_5"
                     /transl_table=11
                     /translation="MKVKVAETAGFCFGVKRAVNKVYELIDTEQKPIFTLGPIIHNEGV
                     VADLEARGVHVITEADLDFPDDTLQNGTVVIRSHGVGKAIYDKLKEKNISYVDVTCPFV
                     LKIHRIVEKESLAGNHIIIIGDKDHPEVQGICGWCQGPYTVIKNQEEAEAFVPPKGKKI
                     SIVSQTTFNYNKFKDLVEILCKKRYDNNVLNILNILNTICNATEERQREAKNIAGEVDT
                     MLVVGGRHSSNTQKLFEICKKECGNTYYIQTPVDLDSEMFQCSSYVGITAGASTPNKII
                     EEVQEHVRIKF"
     CDS             complement(6632..7303)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytidylate_kin"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg223_6"
                     /sec_met_domain="Cytidylate_kin (E-value: 8.6e-78,
                     bitscore: 252.6, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGCNIAIDGPAGAGKSTIAKKVAKELSFIYVDTGAMYRAMALYLL
                     NHGVNGENQEEIEAVCSGADISIEYKNGEQIVILNGENVNAMIRTEQVGNMASKSSANP
                     KVRAHLLKLQRTLAEKNDVVMDGRDIGTTILPNAEVKIYLTASADTRAKRRALEYEQKG
                     ESFDLDQIRKDIIERDERDMNREISPLKQAEDAVLVDSSEMGIDDVVNAILNVYKEKVQ
                     K"
     CDS             complement(7489..8949)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HI0933_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg223_7"
                     /sec_met_domain="HI0933_like (E-value: 1.5e-127, bitscore:
                     417.3, seeds: 46, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPVVHIYIDRSEAETWNYDEIDNLQGKINTGEYSMSKVIIIGGG
                     AAGMMAGVFAARNHHEVHILEKNEKLGKKVFITGKGRCNVTNACDTEELFPAMMSNPKF
                     LYSSFYSFTPQDVMEFFEKAGVPLKVERGNRVFPQSDHSSDIIRALERELKKAGAKIHL
                     HTAVQEIVKKPVTESVTDSVNTLESEAALTESGSDAGKSKKGKKSPDIPQEKITGVILT
                     DGTFMEGDAVIVATGGFSYQSTGSTGDGYRFARELGLKVTDIAPSLVPLKTKEDYIPKL
                     QGLSLKNTGLTIKNGKKVLYEDFGEMMFTHFGVTGPMILSASAHIGAKLAKAPNGELSA
                     YLDLKPALTREQLDARILREFEAGPNKQFKNVIGVLFPSSLTPVMLELGGIPAEKKIHD
                     ISREERQHFIDLIKAFPFTITGMGEFKEAIITRGGVSVKEINPGTMESKKISGLYFAGE
                     VLDLDAVTGGYNLQIAWSTAYLAAQAIQ"
     CDS             complement(9061..10473)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: PYC_OADA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: HMGL-like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg223_8"
                     /sec_met_domain="HMGL-like (E-value: 1.8e-46, bitscore:
                     150.5, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 2e-58, bitscore: 189.1,
                     seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELEKKPVKIVETILRDAHQSQIATRMTTEQMLPIVDKLDKVGY
                     HAVECWGGATFDASLRFLHEDPWERLRKLRDGFKNTKLQMLFRGQNILGYRPYADDVVE
                     YFVQKSAANGIDIIRIFDCLNDLRNLQTAVSAANKEKAHAQVALSYTLGDAYTLEYWTD
                     IAKRIEDMGADSICIKDMAGLLLPNKATELVTALKETVKIPIDLHTHYTSGVASMTYLK
                     AVEAGVDIIDTAMSPFALGTSQPATEVMVETFKDTPYDTGFDQKLLSEIADYFRPIRDE
                     ALDSGLLNPKNLGVNIKTLLYQVPGGMLSNLTSQLKEQHAEDKFYDVLEEVPRVRKDLG
                     EPPLVTPSSQIVGTQAVFNVLMGERYKMVTKETKDILLGKYGATVKPFNPEVQKKCIGD
                     EKPITCRPADLLDNELEKLESEMAQYKEQDEDVLTYALFPQVAMDFFKYRQAQKTKVDE
                     KAADKKNGAYPV"
     CDS             complement(10616..11764)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg223_9"
                     /sec_met_domain="OAD_beta (E-value: 2.1e-156, bitscore:
                     511.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYVTETLSNLIHQTAFFSLTWGNYLMIAVACVFLYLAIKKGFEP
                     LLLVPIAFGMLLVNIYPDIMANPEDMSNGVGGLLHYFYILDEWSILPSLIFMGVGAMTD
                     FGPLIANPISFLMGAAAQLGIYAAYFLAIFLGFNGKAAAAISIIGGADGPTSIFLAGKL
                     GQSALMGPIAVAAYSYMSLVPIIQPPIMKLCTTEKERKIKMDQLRPVSKLEKILFPIVI
                     TIVVCLILPTTAPLVGMLMLGNLFRECGVVKQLTETASNALMYIVVILLGTSVGASTSA
                     EAFLNADTLKIVVLGLVAFAIGTFGGCMLGKLLCKLTHGKINPLIGSAGVSAVPMAARV
                     SQKVGAEADPTNFLLMHAMGPNVAGVIGTAVAAGTFMAIFGV"
     CDS             complement(11781..12149)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 63; E-value:
                     6e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg223_10"
                     /sec_met_domain="Biotin_lipoyl (E-value: 5e-20, bitscore:
                     63.0, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYTITVNGTAYEVTVEETGSVSAPAAAPKAAPKAAPAAAPKAA
                     APAAGAGAVKVTASVPGKVVKVAASVGQAVKAGDSVVILESMKMEIPVVAPQDGTIASI
                     DVAEGASVENGDTLATMN"
     CDS             complement(12177..12932)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg223_11"
                     /sec_met_domain="OAD_gamma (E-value: 3.5e-27, bitscore:
                     86.6, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKMIKKITSVFMTFLVMAALVIGSTSAVFAADKVDDTVKSTLVTT
                     AEGLTDAIVQLKDEEIENYMSSGDDFTTSAMQSWQTSKDELGAKKDSNGETTVTFKDDQ
                     YTVTVPLKFEKADANFVYVFDSQGTPTSMSVDVQYGMGKTLQRAGLNTLMGIGTVFVML
                     ILLSLLISLFRFIPNPEAKKAAEAKAAKAAKEAEAAAIAQTAPAQAEENLADDGELVAV
                     IAAAIAAAEGTTTDGFVVRSIRKVKRNRR"
     CDS             complement(12947..14383)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg223_12"
                     /sec_met_domain="CT_Vparvula (E-value: 5.4e-136, bitscore:
                     445.7, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNATQSLAGTRITSLLDANSFVEIGQGVTARSTDFNMTANKAPS
                     DGVITGYGVIDDKLVYVYSQDASVLNGTVGEMHAKKITRLYDLAMKTGAPVIGLVDCAG
                     IRLQEATDALEAFGQIYLKQTLASGVIPQITAIFGTCGGGMAVIPSLTDFTFMESKKGK
                     MFVNTPNALEGNNTDKCDTAAADFQSKETGVIDGVGTEDEILGQIRSLVSLLPSNNEDT
                     DNYTECTDDLNRVCADLANCAGDTAIALSQIADNGEFFETKADYAKDMVTGFIRLNGAT
                     VGAVANRSEVYDAEGKKTETFDGSISARGARKAADFVKFCDAFDIPVLTLTNATGFMAT
                     LCSEKMMAKSVGELVAAFADATVPKVNVIIGKAYGTAYVAMNSKSIGADLVYAWDNAEI
                     GMMDASLAAKIMYADADAAELNEKAAQYRELQNGVASAAARGYVDTVISPADTRKYVIG
                     AFEMLFTKREDRPSKKHGTV"
     CDS             15047..17044
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) baiH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg223_13"
                     /sec_met_domain="baiH (E-value: 8.5e-145, bitscore: 475.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSNYQHIFTPLTVKNMTIKNRIVMMPMGTNYGEQNGEMSFLHIN
                     YYKERAKGGTGLIIVENASVDSPQGSNGTTQLRIDHDNYLPRLYKFCEEIHKYGTCIAI
                     QINHAGASAVSARTNMQPVSASDVPSKEGGEIPRPLSVEEIHHIVKKYGEAAKRAQAAG
                     FDAVEIHAGHSYLISQFLSPLTNKRTDEFGGSVENRTRFCRMVIEEVRKQVGPFFPIML
                     RLSADELMEGGNTLEDTLEYLEYVQDEVDIFDVSCGLNGSIQYQIDANYMKDGWRSYMP
                     KAVREKFGKPCISMGNIRNPKVAEQILADGDADLIGMGRGLIAEPAWVNKVATGRECDL
                     RKCISCNIGCAGNRIGFNRPIRCTVNPAVLEGDVYKNQKVNKNCNVVVIGGGTAGLEAA
                     CTAAEVGCNTFLLEKGETLGGLASVISKIPAKKRLADFPNYLIHRAEQLENLYIFTNTE
                     GTPENIRKFHPNLIVSSTGSAPLLPPIRGLHDRIDKEGSKVASILGMINHINDYPEDMT
                     GKKVVVVGGGAVGLDVVEFFAARNAEISIVEMMDQIGRDLDPVTKNDMKDQMKKHHVAQ
                     LTKTALQEVKDSSFLVKDAEGERELPFDYGFVCLGMKAQGQLFAELSDAFVSDDVEILN
                     IGDSKRARRIIDGTLEGRNILNTLTQMGYL"
     CDS             17084..17962
                     /locus_tag="ctg223_14"
                     /transl_table=11
                     /translation="MAERITGHTELIGLMAYPIRHSSSPAMQNEAFAKLGYDYAYLAFE
                     VGADEIEDAVKAIRTLKMRGSNVSMPNKTLVGKYLDELSPAAELCGAVNTIVNDNGHLT
                     GHITDGIGFMSALKDNDIDVIGKKMTIVGAGGAATAIEIQAALDGVAEITIFNRKDEFW
                     DRAVSTVEKINTKTSCHAVLYDLADLDKLKAEMDDSFIFVNATGVGMKPLEGQSVVPDK
                     SYFRPELIVIDVPYSPLETKMRSMAKEVGCKTMNGLGMMLFQGSAAFELWTGEPMPIEH
                     MKEILHISYDD"
     CDS             18231..18992
                     /locus_tag="ctg223_15"
                     /transl_table=11
                     /translation="MNTVQVKNTVIGEGRPKICVPIVGKTKTDILEEAKKITTLPVDVV
                     EWRVDWFDDVFATEKVLETAKELQEVLKDIPVLLTFRTSKEGGEKEISVNDYAALNIAA
                     AQSGYVDLIDVEAFTGDEVVKTIINAAHEAGVKVIASNHDFFKTPEKEEIIRRLCMMQE
                     LGADIPKIAVMPTCKQDVITLLSATLEMSEKYADRPIITMSMAGTGVVSRLTGETFGSA
                     LTFGAASKASAPGQVGVHELKQVLDIIHSSL"
     CDS             complement(19173..20531)
                     /locus_tag="ctg223_16"
                     /transl_table=11
                     /translation="MANTRTQRRENELPYIPFGPFQIRLPFIHYKIESVEFIQGLILGV
                     TALAAVPYLEQYLGLPYELAWSCVIIETFLYLLHSLLGDPVVPGWITPTLPLTIVFLEG
                     FPMGEERIQAMIALQMLVGLVFIFMGVTRLADKFVHAVPNSVKGGILLAAPVTVMAGQL
                     GENGNMHKYPLAIVAGVGLLILISFSDKYQEKRKTNKFLDLVARYGNLFPYLIAMVVGL
                     LVGELDAPGLEIGTFIKIPQFKDIIDQVSIFGVGIPPASMFIKALPLALVCYVIAFGDF
                     VTTETLVSEARHARDDEYIDFNSSRSNLVSGLRNLILSIIAPFPPLSGPLWVGMTVSVS
                     MRYKEGKKAMKSLLGGMASFRLATFLSVLIIPVVSFFRPIFGVGSSITLMFQAFVCARI
                     GMDYCKSDRDKMIAGVMAAVLATQGTAWASAWALAVGFGLNIFLSNWNPFEKK"
     CDS             complement(20823..22022)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 50.4; E-value: 5.4e-16)"
                     /gene_kind="transport"
                     /locus_tag="ctg223_17"
                     /sec_met_domain="MFS_1 (E-value: 4.4e-16, bitscore: 50.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQKTNKMLIFTSLAAYFTYFIHGIGASILGQYKPEFAAAWGAKP
                     LADGTLDVSMVVSVIAALGLGRLISLPFSGPLSDKYGRRLSGIIGVLCYVAYFFGMANS
                     TSMAMGYAFAVIGGIANSFLDTCVSPTCMEIYVNNPSVANLFTKFSICLSQFLLPFLIG
                     IVASANMSYKTIFIVAGIAILIDGILILILPFPAREKAVQAKADKKKSGHKISPAAIAA
                     ILIGFTSSSTFMLWLNCNQELARSYGMADPSKIQSLYALGTATAILATAAFIKKGLKEI
                     SVLILYPLISTIMLALCYFIQAPFICLVGGFVIGYAGAGGVLQLAVSTTAEFFPENKGT
                     ATSLVMIASSIANYTILSLAGYITKVGGSSAPRMILLLNMAVTIVGILLALFVKKNRNQ
                     "
     CDS             complement(22043..22927)
                     /locus_tag="ctg223_18"
                     /transl_table=11
                     /translation="MEQRIKGTTGLMALIGSPVGHSGSPAMYNFSFRHHNLDYAYMAFD
                     IKEDQVPAALDAIRLFKMRGANVTMPCKNEAAKHMDELSPAARIIGAVNTIVNEDGKLV
                     GHITDGIGFVRNLKEHGVDVKGKKMVVLGAGGAATAIQVQCALDGAESISIFNPKDPFF
                     ARAESTAEKLSKETPDCKVSVFDLADEAKLKEEVANADILVNATLAGMKPHEELTLIKD
                     KSMFRPDLVVADVVYNPAETRMVKEAKEAGCKLAIGGKGMLLWQGAAAYKLYTGLEMPT
                     AKYQKFQEENENK"
ORIGIN
        1 ctattacact tatcctttct gtattcgtat ctatttcatt taaacgactg tttatagagg
       61 caggacacaa taatttttaa tcttcttatc ttcatggggt ctgaccccac atactacaga
      121 tgctttcttg ccttcattgt cacatagtac accaaaccac cgagcattcc acctactgta
      181 ttgtagaaga tatccgatag ctgaaacgta cccaatctaa gcaataattg caacatctca
      241 atgcttaccg aaaagatgaa cgctatcttc ccgctatacc acagtatctt cttccagccg
      301 tttcctgtct tttctttgaa tgtccacatc actaccgaac taaacggcac cattatgatc
      361 acattctcta tgcactcagt tgtaagtttc tgctcgccgt tcactgtctc ccagatgccc
      421 cagccaccca tgaccttgga taacggattc atccacaaat tacggttcaa tagtgttcgg
      481 aataaaatca tcgaagtcac aaaaaacaac agaaacaact tccgaaagaa cacgctctct
      541 ttgaatttct gataccatgt atcatttgtt ttcagaacct tcacagatat cttcccatgc
      601 tccagcagtt caccgatgaa gataggaatc agatattctg cctttagtgg attacccggc
      661 acttccttct cgaagaattc tttgaatccc tcttccagcg ttgtaaggaa atcaggagtt
      721 aagccccaca tattcatgga aaccagagaa tcaacatcaa cagccattcc ttctgcctct
      781 gctacagctg cggtctttac aatgttcttc gtttccacga cctcggtcag gttgtaatcc
      841 tcatccatct tgcagatacc gcgagtcacg ccaccgttat cagacagcgt gttcttcagc
      901 acaaaacctg ccatacagga cttgccgcca ttcaccagat actcatgaac agccttgaaa
      961 ccttctttgc catagtaatc atctgcattg atgacgatga acggggtctt gatgaccttc
     1021 ttcgctgcaa gcacggcctg accagttccc cacggctttg tacggccttc cggcagagtc
     1081 cccggaatat cgttaatgtc ctggaaagca taatccaccg gctctaactg cttgattcct
     1141 gttccgaagc ggctgccaat accagctgcc atgataagta atgttgtttt cataattctc
     1201 ctttccatac cttgtagcgc ccaatgtgcc ttccacaaaa ttttatgtag ttattagagc
     1261 agcgccagta gcctatgctc tcgttttcgt ttatagtttc tttagagaaa aatcatttct
     1321 tcttcatggg gtctgacccc gagaggctat ttagaagaaa tcaaagctct ggctgtacag
     1381 aagaccgcat aacttttgtt agcaggtttt tatgtctttt ttatctcaaa tattatagct
     1441 ttttctgtcc atatctgtta gaattgacaa tgattaataa caggggctgc tgcacataca
     1501 gatgcggcag tccctgtcga atggatgagg aaaattaaaa tgaacacaac agcaaatctt
     1561 ggcaaggcac ccgtacgcac tctggtgctc cagcttgcca tcccttctat gaccgcgcaa
     1621 tttgtcaatg tactttacag cattattgac aggatgtata tcggacatat ttcccaaaat
     1681 ggtgcactgg ctcttgcagg tgcaggggta tgcggtccta tcgttacatt tctcacttct
     1741 tttggcactc tggtaggaat cggaggttcc attaccatgg gaatccgaat gggagaaaaa
     1801 aatcataaaa aagcagaaca ggtactggcg aattcttttc tggtgctcag tattttttct
     1861 gttctgctga ctatcagctt tcttcttcta aaagataagc tgcttatgtg gtttggcgca
     1921 agtggggcta cttttccctt tgccaatacc tatctgacca tttatacaac aagtaccttt
     1981 ttcgcactga tggctacagg gcttaattac tttatcaact gtcagggctt cccccttgta
     2041 ggaatgttta ccgtactgat cggcgcagga tgtaacatcc tgttagaccc gatttttatt
     2101 tttggttttc atatgggaat ttccggcgct gccattgcaa cggttatttc gcagatactc
     2161 tcctgcatct ttgcaatgac cttcctgtta ggaaaaaagg ttcctgtaaa gattaccttc
     2221 ggacaataca acttaaaagt cataaaaaaa atcctttccc tgggattttc tccttttctg
     2281 atcctggcca cagacagcct gatactgatc tttatgaata cagtgctcca gaaatatggt
     2341 ggtgcttccc agggcgatat actgatcacc tgtgccacca ttgctcaaag ctatctgctt
     2401 ctgatcacct cacctatgat cgggatcagc ggaggtacac aggcaatctt gagctacaat
     2461 tacggtgcca gatgcgtaaa cagggtcaaa gacgcagaaa ggaacattct aggagtaatg
     2521 cttatcttta ccaccatcat gttccttctc tcccggttca ttccccggta ctttgttctt
     2581 ctgtttacca ctgatccaca gtatatcaga ttctctgtct ggaccatccg tacctataca
     2641 ctgatgatca ttccgctaag cttccagtat gtctttgtag acgggctgac tgccctggaa
     2701 tgtccaaaga caggacttgc gctctccgtt accagaaaat ctctttttgt gatcagtgca
     2761 gctgtcttgc cctctttctt tggtgcaaaa gcggcttttt tcgcagaacc tgttgctgac
     2821 ggaatctctt ctgtcctctc aacagttgta ttcttgcttc tgatcaaccg ccacctggat
     2881 aaacgctgcc agatggataa ggaagcgatc ctgtaaatta ctcctgtatc tccgcatttg
     2941 ggagatacag aaataagtat aattgtgcag aaatctattc tatttgatgc tttcgttgtt
     3001 cctacgccaa tcaaatcctc tacttctttt cttgtaacgc ttccattttt tctcctcatt
     3061 cctattgtca agcggatatt cgcaatccgc ttcgctacgc ggctctacac cgaataactg
     3121 ctccgcagtt tatcagaagg agcttgcact cctcctgata caagcaagtc cccacccact
     3181 gctgattgct tttcgcaatt gaagcagagt atattccatt taatgtttcc caggccggat
     3241 ttgagatcat gtatcaccga tttgcactgt ccggagaccg gatgtatcat cagctatata
     3301 acactctgga aacttatgaa tatacaggaa acttcctgaa tcttctgtcc tctgatataa
     3361 tggatgagaa aggaaatgat ctatctgcag atactaatgg aaaactttat gtttctctct
     3421 cagcaaaaaa aggaatcgtc ataaaagatg aacaaaccac agcaaagcat gacataagcg
     3481 gcaacctgac catgcatccg tccggagcgt ggggactggc ctattcctat agcaatgata
     3541 cggagaaaat aacattccag gatggcaaca tactcaaaga accctggatc ttaacctcaa
     3601 tggatgatga cgaagtacga accggtattt ttaaacaagt cagtctgatt gagatcggaa
     3661 atgaacatat tatggtatac ggatgtcttg tcggagatga tgccccatat aaaatagcag
     3721 tatatgatca ggatggaaac cagcagttgc ttcttggtcg tgatccatcc gatgattctg
     3781 cttcttttgg ctacatcact ggagtagcag agacagcaaa cggatatatt gcaacagatg
     3841 gaaatgccag aatactctac ttctggtcaa aagacggaac tcttctcggt aaaatacaat
     3901 gcagcgatat tttcggaacc agatacccct ggcttgaaga tataaaagtc gcagacgatg
     3961 gttctgcaat ttttcctgtg atgctgtctg cattgatctg catacagaca cccatatcta
     4021 ccagttcttc cacaaaatcc atattggtgc gtgtggcctc ataacgttct atatgcgcca
     4081 cgattggctt atatccccct gacagcagtg tgctgagacg ttcgcgtata taattctctt
     4141 ctgaattatg agaaaattct gtgagaacat atcgggagcc tgccattgtc atgaccttat
     4201 tttctctgag catggagatc atctccatat ttgtgtgaaa ttcacacccc agatatacat
     4261 gaagatccga agcgacttct gctgctgctt tctccaccag tttaaactgc tcttttacct
     4321 tctctgctga tgtttcaaac attcgaaagc gaaaatgagg ggttgcaata attgtcctta
     4381 caccctgttc atattccatt cggagcaatt ttcctgtttc ttctatgtct gtggctccat
     4441 cgtctacccc gggtacaata tggcaatgta tatcataaat tccttttccg gacattctat
     4501 tactccttcc tgatcacctg taaacgaata tattttctgt cggcaatgtt atttataatt
     4561 ttcctgtaac tgctgaccgt atttataatc cgaaaaatca accggctccg tatgatcaat
     4621 ctcatacaaa gccggttgat aaatattcat gagtattctt ttatgagtaa tctcttatta
     4681 ttcttctgca gcttcctcag ccggtgcctc aagagctttc atgctcaggc tgatcttctt
     4741 gtcttctccg ttgaagtcaa caaccttagc ttcgatctcc tgtccgattg acagtacatc
     4801 tgcaggtttg gcaacgtgct ctctggaaat ctgggatacg tgaagaagtg catctacacc
     4861 aggtgcaagc tctacgaatg cgccgaagtc tgtcatacgt gcaactttac ctttaactac
     4921 gtttcctaca gcgaagtcct cagctgctgt gagccatgga tttgcttccg ggaatttaag
     4981 ggaaagtgcg atcttctctc cgttgatctc tttgataagg actttaactt tatcgccaac
     5041 agtgaatact ttcttcgggt tctctactct gccccaggac atttcggaga tgtgaagaag
     5101 tccgtctgct ccgcccagat cgatgaatgc accgaaatct gtaacgttct taactgttcc
     5161 ttcaactgtg tcaccaacat ggattctctc cattaattct ttctgtttct ctgctttctc
     5221 agcaagaaga agctgcttac ggttaccgat gatgcggcgt cttctcggat tgaattctgt
     5281 gataacgaat tcgatctcct gatctgcata tttggaaagg tctttctcat atgtgtcgga
     5341 aacgaggctt gcaggaatga atactcttgc ttcgtctacg tttacacaaa gtccgccgtc
     5401 aagtacctga gttacaggag cttttaatac ttcctgattc tcaaatgctt cttcaagacg
     5461 tttgttgcct ttctctgctg ccagtctctt gtaagtaaga gtaacctgac cttctccatc
     5521 gtttactttg agaacttttg cttccattgt gtctccaacg tgaacagcat ctgtgagtac
     5581 aaggcttgca tcgttagagt attcgttctt tgtgataata ccgtctgctt tataaccgat
     5641 attcagaata atctcatctt cttttacatc gatgacagta ccctgtacaa tctctccatt
     5701 tctgatagtc tttacggaat cttccagcat ttgttcaaaa cttaattctg acatgttctt
     5761 gaacctcctc aataattttg tttggggtgg aagcccctgc tgtaatacct acataactac
     5821 tgcattggaa catttcagaa tccaagtcta caggtgtttg tatatagtaa gtatttccac
     5881 attccttttt acatatttca aacagctttt gagtattgga actatgccgg ccacctacga
     5941 ccaacatagt gtctacctct ccggctatgt tttttgcttc tctctgccgt tcttcggtag
     6001 cattacaaat agtgtttaaa atattgagaa tatttaaaac attattatca tacctctttt
     6061 tgcaaagaat ttcaactaaa tctttaaatt tgttgtaatt aaatgtcgtc tgggacacaa
     6121 tgcttatttt tttgcctttt gggggtacaa atgcttcggc ttcttcctgg tttttgatca
     6181 ctgtgtacgg tccctgacac cagccgcaga tgccctgtac ttcggggtgg tctttgtcgc
     6241 cgatgatgat gatgtggttt cctgcaaggc tttctttttc cacaatcctg tggattttca
     6301 gaacgaaggg gcaggtcaca tctacataag agatgttttt ttctttcagc ttatcgtaga
     6361 tggctttgcc tacaccgtga gagcggatga ctactgttcc gttctgcagg gtatcatccg
     6421 ggaaatccaa gtctgcttct gtgataacat ggacgccacg ggcttccaga tccgctacta
     6481 cgccttcgtt gtggatgatc gggcccagag tgaaaatagg tttctgttct gtgtctatga
     6541 gttcgtagac tttgttcact gcacgtttaa cgccgaagca gaagcctgct gtttctgcta
     6601 cttttacttt cataaaataa tccttcttaa attatttctg cactttttcc ttatatacat
     6661 taagaatcgc atttacaaca tcatcaattc ccatttccga ggaatctacg agcactgcgt
     6721 cctctgcctg tttcagaggg gagatttcgc ggttcatgtc gcgttcgtcg cgctcgatga
     6781 tgtcttttcg gatctggtcc aggtcgaagg attctccctt ctgttcatat tccagtgctc
     6841 ttctttttgc tctggtgtct gcgcttgctg tgaggtagat ttttacttct gcgtttggaa
     6901 ggatggttgt gccgatatct ctgccgtcca tgactacgtc gtttttctct gccagagttc
     6961 tctgaagttt cagaaggtgg gctctgactt tcgggtttgc ggagcttttg gatgccatgt
     7021 ttcctacctg ttcggtgcgg atcatagcat ttacgttctc tccgttgagg atgacaatct
     7081 gttctccgtt tttgtattcg atggagatgt cagcgccgga acatacagcc tcgatctctt
     7141 cctgattttc tccgtttacg ccatggttca gaagatataa agccattgcc ctgtacatgg
     7201 ctcctgtatc tacatagata aatgataatt ctttcgctac tttctttgcg atggtgctct
     7261 ttcctgctcc tgcaggtccg tcgatggcta tgttacatcc cattttcgtg gttcctcctg
     7321 tttctattat tcaaacagat tttctctgtt ttattattaa tgtttattaa tcagtcaagc
     7381 ggatattcgc aatccgcttc gctacttgct cataaccgaa tcatagatat aattcgcata
     7441 cacggtactc atcatctgct tgtttctgtt gtttctatag taagcaactt actgtatggc
     7501 ctgtgctgcc agatatgcgg tagaccaggc aatctgtaag ttatatccac ctgtcactgc
     7561 atccagatcc agtacctcgc ctgcgaagta aagacctgag attttctttg attccattgt
     7621 tccgggattg atctctttga cagagacgcc gcctctggta atgatggctt ctttgaactc
     7681 acccattcct gtgattgtga aggggaaggc tttgataagg tcaatgaagt gctggcgttc
     7741 ttctctggag atatcgtgga ttttcttctc tgcggggatt ccacccagtt ccagcattac
     7801 cggagtcaga gatgacggga aaagtacgcc aatcacgttc ttgaactgtt tgtttggtcc
     7861 tgcttcaaat tcgcgcagga tcctggcatc cagctgttct ctggtaagtg ccggcttcag
     7921 atccagatat gcagacagtt cgccgtttgg tgctttcgcc agttttgcac caatgtgggc
     7981 actggcggac aggatcatgg gacctgtgac tccgaaatgg gtgaacatca tctctccgaa
     8041 atcctcatag agtactttct ttccattctt tatggtaagt cctgtattct taagggaaag
     8101 tccctgaagc ttagggatat agtcttcttt tgtctttaat gggacaagag aaggtgcaat
     8161 gtctgtgacc ttcaatccaa gttctcttgc aaagcggtat ccatcgcctg ttgagccggt
     8221 gctctgataa gagaatccgc cggttgccac gatgactgca tctccttcca tgaaggttcc
     8281 gtctgtaagg atgactcctg tgatcttctc ctgcggtatg tcaggtgatt tttttccttt
     8341 tttgcttttt cctgcatcag atcctgattc tgttaatgcg gcttctgatt caagggtatt
     8401 tacggaatct gttacagatt ccgttacagg tttctttaca atttcctgta cagcagtgtg
     8461 aagatgaatc tttgctcctg ctttcttcag ctcacgctcc agagcgcgga tgatgtctga
     8521 ggaatggtca gactgtggaa atacgcggtt tccacgctct accttcagag ggacacccgc
     8581 tttctcaaag aactccatta catcctgagg ggtaaatgaa tagaaactgc tgtagaggaa
     8641 cttgggattg ctcatcattg caggaaagag ttcttctgtg tcgcaggcat ttgttacatt
     8701 gcatctgcct tttcctgtga tgaagacttt ctttcccagt ttctcgttct tctctaatat
     8761 atgaacttca tgatggttac gggctgcaaa aacccctgcc atcattccgg cggctccgcc
     8821 gccgattatt ataactttgc tcatggaata ttctcctgta tttattttac cctgcagatt
     8881 gtctatttca tcatagttcc acgtctccgc ttcgctacga tcaatataga tatgtaccac
     8941 tggcagcata tacccattgg cacattatat tcccgggtat catattcttt cataataacg
     9001 caaaggagcc tgcttacgca agctcctttt ttcgtttgga catatttaat tactgatcaa
     9061 ttatacagga tatgctccgt tctttttgtc agctgctttc tcgtcaactt ttgttttctg
     9121 agcctgacgg tatttgaaga agtccatagc tacctgtggg aacagtgcgt atgttaatac
     9181 gtcttcatcc tgttccttgt actgagccat ttcgctctca agtttctcaa gctcgttgtc
     9241 aagaaggtct gcaggacggc atgtgatcgg tttctcatcg ccgatgcact tcttctgtac
     9301 ttccggatta aacggtttta cagttgcgcc gtattttcct aacaggatat cttttgtttc
     9361 ttttgtaacc attttgtatc tctcgcccat aagtacgttg aatacagcct gtgtaccaac
     9421 gatctgtgaa gacggagtaa caagtggcgg ttcaccaagg tctttacgta cacgcggaac
     9481 ttcctcgaga acatcgtaga atttgtcttc tgcgtgctgt tctttcagct gggaagtcag
     9541 gttggagagc ataccgcccg gtacctggta cagtaaagtc ttgatgttaa caccaaggtt
     9601 cttaggattg agcagtccgc tgtcaagagc ttcgtcacgg atcggacgga agtagtcagc
     9661 gatctcggag agaagcttct gatcaaatcc tgtgtcgtat ggtgtatcct tgaatgtctc
     9721 aaccataacc tctgttgcag gctgggatgt tcccagtgca aatggagaca ttgctgtatc
     9781 gatgatatcc acacctgctt ctactgcttt taagtaagtc atggaagcta cacctgaggt
     9841 gtaatgtgta tgaaggtcga tcgggatctt aactgtttct tttaatgctg ttacaagctc
     9901 tgtagctttg tttggaagga gaagacctgc catatctttg atacagatgg aatcagcgcc
     9961 catatcttca atacgttttg caatgtctgt ccagtattcc agtgtgtaag catctcctaa
    10021 tgtataggaa agagctacct gtgcatgagc cttctctttg tttgcagcgc ttactgctgt
    10081 ctgcaggtta cgaaggtcat tgaggcagtc aaaaatacgg atgatgtcga ttccgtttgc
    10141 agcagatttc tgtacgaagt attctacaac gtcatctgca tatggacggt atccaaggat
    10201 gttctgtcca cggaaaagca tctgaagttt tgtgtttttg aagccgtcac gtaatttacg
    10261 aagtctttcc catggatctt cgtgaaggaa acgaagggat gcatcgaatg ttgcaccacc
    10321 ccagcactct actgcgtgat agccgacttt atcaagttta tctacgatcg gaagcatctg
    10381 ttctgtggtc atacgtgttg cgatctggga ctgatgagca tcacggagaa tggtttccac
    10441 aattttaaca ggttttttct ctaattctgc cattattaaa tctcctttat agttctgttt
    10501 aatcggatat tcgcaatccg cttcgctact tgctcataac caaatagctg ctccgcagct
    10561 tatcagaagg agttgcactc ctcctgatac aagcaagata gcttgcttga tttggttata
    10621 ctccgaaaat agccatgaat gttccggctg ctacggctgt accgataaca ccggcaacgt
    10681 tcgggcccat tgcgtgcatc agaaggaagt ttgtaggatc tgcctctgca cccactttct
    10741 gggatacacg ggctgccata ggtactgcgg atacacctgc ggaaccgatc agcgggttga
    10801 tctttccatg agtcagtttg cagagcagtt taccaagcat acatccgccg aatgtaccga
    10861 ttgcgaatgc aacaagacct aaaactacga tcttcagagt atctgcgttt aagaatgctt
    10921 ctgcacttgt ggaagcacct acggatgtac ccagaaggat aactacgata tacatcaggg
    10981 cattggaagc tgtttctgtc agctgtttta caacaccgca ctctctgaac aggttaccaa
    11041 gcatgagcat accaaccagc ggagctgttg taggcaaaat caggcagaca acgattgtga
    11101 taacgatcgg gaacaggatc ttctccagtt tggaaaccgg gcgaagctga tccattttga
    11161 tcttacgttc tttctctgtt gtgcagagtt tcatgatagg cggctggatg atcggaacca
    11221 gtgacatata ggaatatgct gccactgcga tcggtcccat cagtgcagac tgtccaagtt
    11281 tacctgcaag gaaaatggaa gtcgggccat cagcaccacc gatgatggag atagctgccg
    11341 ctgcttttcc gttgaatcca aggaagattg caaggaagta agctgcatag ataccaagct
    11401 gtgctgcagc acccatcagg aagctgatcg ggtttgcaat cagcggaccg aagtctgtca
    11461 tggcacctac acccatgaag atcagggatg gtaagatact ccactcatca aggatgtaga
    11521 aataatgaag aagtccacct acaccattag acatatcttc cgggtttgcc ataatgtccg
    11581 gatagatatt tacaagcagc ataccgaatg cgataggaac aagcagaagc ggctcgaatc
    11641 ccttcttgat agcaaggtaa aggaatacgc aggctactgc gatcatcagg taattgcccc
    11701 atgtcaaact gaagaatgct gtctgatgaa tcaggttgga caatgtttct gttacataag
    11761 acatttgact acctcccgtc ttagttcatt gttgctaaag tatctccgtt ttctacagag
    11821 gcaccttctg caacatcaat gcttgcgata gtaccatcct gaggagctac tacagggatt
    11881 tccattttca tggattcaag aataactacg ctgtctccgg cttttactgc ctgtccaacg
    11941 cttgctgcta ctttgacaac tttgccaggt acggaagcag ttacttttac tgcgccggcg
    12001 cctgctgcag gagctgctgc tttcggagct gctgcaggtg cagccttagg tgctgctttt
    12061 ggagctgctg caggagcgga tacgcttcct gtttcttcaa cagttacttc atatgctgta
    12121 ccatttactg taattgtata gcttttcatt ttaaaatcct cctaaataaa tgacaattat
    12181 cttctatttc tttttacttt acggatggaa cgaactacga agccgtctgt tgtagttcct
    12241 tctgctgctg cgatggctgc tgcgataaca gctaccagct ctccgtcatc tgcaaggttc
    12301 tcttctgcct gtgcaggtgc tgtctgtgcg atggctgctg cctctgcctc ttttgcagct
    12361 ttggctgctt ttgcttctgc tgctttcttt gcttccggat tcggaataaa tctgaacaga
    12421 gaaatcagaa ggcttaataa aatcagcatt acgaatacag ttccaatacc catcaaagta
    12481 ttaaggcctg ctctctgaag agtcttgccc ataccatact gtacatctac agacatggaa
    12541 gtcggtgttc cctgtgagtc aaagacatat acaaagtttg catctgcttt ctcaaattta
    12601 agaggaacag taactgtgta ctgatcatct ttgaaagtta cagtggtttc accattgctg
    12661 tccttctttg cgccaagttc atccttggat gtctgccagg actgcatggc acttgttgta
    12721 aagtcatctc ctgaactcat gtaattctcg atttcttcat ctttaagctg gacaatggca
    12781 tctgtcagtc cttctgctgt agttaccagt gtggacttaa cagtatcatc aaccttatct
    12841 gcggcaaata ccgcagaggt gctgccgatc accagcgcag ccattacgag aaatgtcatg
    12901 aatacagaag ttattttttt gatcattttc atatgcgtca ccccgcttag accgttccat
    12961 gtttcttaga cggacgatct tctctctttg tgaacagcat ctcaaatgca ccgattacat
    13021 attttcttgt gtcagccggg ctgatcacag tgtcaacata gcctcttgct gctgcggaag
    13081 caacaccatt ctgaagctct ctgtactgag cagctttttc attcagttca gcagcatctg
    13141 catctgcgta catgatcttg gctgccaggg aagcatccat cataccgatc tctgcgttat
    13201 cccatgcata tacaaggtct gcaccgatag atttgctgtt cattgccacg taagctgtac
    13261 cgtaagcttt gccgatgatc acatttacct tcggaacagt tgcatctgcg aatgcagcta
    13321 ccagttcacc tacggatttc gccatcatct tctcgctgca taaggttgcc atgaagcctg
    13381 ttgcgtttgt aagtgtaagt accggaatat caaaagcgtc gcagaatttc acgaaatctg
    13441 ctgcttttct tgcgcctctt gcagagatgc ttccgtcaaa tgtttctgtt ttcttgcctt
    13501 ctgcgtcata tacttcgctt ctgtttgcaa cagcacctac tgtagcgccg tttaaacgga
    13561 taaagcctgt aaccatgtct tttgcatagt ctgcttttgt ctcgaagaat tcaccgttgt
    13621 cagcgatctg ggaaagtgcg attgctgtgt cacctgcaca gtttgcaaga tctgcgcata
    13681 cgcggttaag atcgtctgta cactctgtgt aattgtctgt gtcttcatta ttagaaggaa
    13741 gaagtgatac taaggaacgg atctggccaa gaatctcatc ctctgtacca acgccatcga
    13801 tcacacctgt ctctttgctc tggaaatcag ctgctgctgt atcgcatttg tctgtgttgt
    13861 ttccttccag tgcgtttggt gtgttgacga acatttttcc ttttttggat tccatgaatg
    13921 tgaaatctgt cagggacggg ataactgcca taccaccgcc gcatgttccg aagattgctg
    13981 tgatctgcgg gatcacaccg gatgccaatg tctgtttcag atagatctgt ccgaaagctt
    14041 ccagtgcgtc tgttgcttcc tgaagacgga tacctgcaca gtcaacaagt ccgataaccg
    14101 gagcgcctgt tttcatggca agatcataaa gtcttgtgat cttctttgca tgcatttcac
    14161 caacagtacc gtttaataca gatgcatcct ggctgtatac ataaaccagt ttgtcatcga
    14221 tcacaccata tccggtgata acaccgtcag atggtgcctt gtttgcagtc atgttgaaat
    14281 ctgtggatct ggctgttaca ccctgtccga tttcgacaaa actgtttgcg tcaagcaaag
    14341 aagtaattct tgtgcctgct aagctttgtg ttgcattact cattcttgtt tgccctccat
    14401 ctttatgaga atatttaaaa gttaacccaa aaatttagcc gattttaatt ttaccttttt
    14461 cggcagaaaa tttcaacatt tatttgtcat tttcgttaaa aatatagcag aaaaatttgt
    14521 caggtttctc caaattttgt ttttttgagt atttcttcct atttaataga gggtattacg
    14581 gttattttgt attgtcctgt atttcaccct ctcccgcaaa ccagtgtgtc gacaagttga
    14641 tttctcgaac aatcctgcgt ctgaatttct tatttctatc ctgcaagatt gtttcaagaa
    14701 tcaacttgtc ggcacaccag agcgtgtttg aagcaactat accacacact tgtctgcgaa
    14761 tccgactgca caggtataaa agtctcagcg cagcccggcg aaacaatact atagccatac
    14821 aggttcagca ggattttccc atgatgtgga tgcagttgcg aatgctttca ttcagtacgc
    14881 ggacagtgca cggaaaacca tagatgtttt ttattatata gcacgaatta tcaattagat
    14941 ttatggatta tcccgttata taattaacac atcaaagaaa ttcaggccac agctaaagca
    15001 ctgaacagct atagatacaa cagaaaattt caggaggaaa gacgtaatga aaagcaatta
    15061 ccagcatatt ttcacaccac tcacagtaaa aaatatgact atcaaaaacc gtatcgttat
    15121 gatgcctatg ggaaccaatt acggggaaca gaacggcgaa atgagttttc ttcacattaa
    15181 ttattataaa gagcgtgcca aaggcggcac aggtctgatc atcgtagaga atgcaagcgt
    15241 agattctccg cagggttcca acggaactac tcagcttcgt attgaccacg acaactatct
    15301 gccgcgtctg tacaaattct gtgaagagat ccacaaatat ggtacctgta ttgcgatcca
    15361 gatcaaccac gcaggtgctt ccgctgtttc cgcacgtaca aatatgcagc cggtttccgc
    15421 atctgatgtt ccgtccaaag aaggcggaga aatcccgcgt ccgttatcag tggaagaaat
    15481 ccatcacatt gtaaagaaat acggcgaggc tgcaaagaga gcccaggctg caggttttga
    15541 cgcagtagaa atccatgcgg gacattccta tctgatcagc cagttcctct ctcctcttac
    15601 aaacaaacgt acagatgagt tcggcggatc tgtggaaaac agaacacgtt tctgccgtat
    15661 ggtcattgaa gaagtaagaa aacaggtcgg acctttcttc ccaatcatgc tccgtctcag
    15721 cgcagatgag ctgatggaag gcggcaacac tcttgaggat actcttgaat atctggaata
    15781 tgttcaggat gaagttgata tcttcgatgt ttcctgcggt ttaaacggtt ctatccagta
    15841 tcagatcgat gccaactaca tgaaagacgg atggcgttcc tatatgccta aagctgtcag
    15901 agagaaattc ggcaagccat gtatctccat gggaaatatc cgtaacccga aggttgccga
    15961 gcagatcctc gctgacggcg atgcagacct gatcggtatg ggacgtggtc ttatcgcaga
    16021 acctgcatgg gtgaacaaag tagctacagg cagagaatgt gaccttcgca aatgtatctc
    16081 ctgtaacatc ggatgtgcag gaaacagaat cggctttaac cgtccgatcc gctgtactgt
    16141 aaacccggct gttctggaag gtgatgttta taagaatcag aaagtgaaca aaaactgtaa
    16201 tgttgtagta atcggaggcg gtactgccgg actggaagct gcctgtacag ccgcagaagt
    16261 aggctgtaat accttccttc tggaaaaagg tgagactctt ggcggtcttg cttctgtgat
    16321 ctctaagatt cctgcaaaga agcgtctggc tgatttcccg aactatctga ttcacagagc
    16381 agagcagctt gagaatcttt atatcttcac aaacacagaa ggaacaccgg aaaatatccg
    16441 caaattccat ccgaacctga ttgtaagctc cacaggttcc gcgccactgc ttcctccgat
    16501 caggggactt cacgaccgca ttgacaaaga aggcagcaag gttgcttcta tcctgggaat
    16561 gatcaatcac atcaatgact atccggaaga tatgacaggc aagaaggttg ttgttgtggg
    16621 cggcggtgct gttggtcttg atgttgtgga attctttgca gcaagaaacg ctgagatttc
    16681 tattgtggag atgatggatc agatcggacg tgacctggat cctgttacaa agaatgacat
    16741 gaaggaccag atgaagaaac atcatgtggc ccagcttaca aagacagctc ttcaggaagt
    16801 aaaagacagc tctttccttg taaaagatgc agaaggtgaa cgtgagcttc catttgacta
    16861 cggattcgta tgtcttggta tgaaagctca gggacagctt ttcgcagagc tttccgatgc
    16921 ttttgtttct gatgatgttg agatcctgaa catcggagac agcaaacgtg caagaaggat
    16981 catcgacgga actctggaag gaagaaatat ccttaataca ctgactcaga tgggatacct
    17041 ttaacaaaaa cctttacaac aaaatacgaa aggggatatt ataatggctg aaagaattac
    17101 cggacatact gaattaatcg gtctgatggc ttacccgatc cgtcactcca gctctcctgc
    17161 aatgcagaat gaggcttttg caaaactcgg gtatgactac gcttaccttg ctttcgaggt
    17221 tggcgcagat gaaattgagg atgcagtaaa agcaatccgt actctgaaaa tgagaggatc
    17281 caatgtttcc atgccaaaca aaactctggt tggaaaatac ctggatgagc tttctcctgc
    17341 tgcagaatta tgcggtgcag ttaacacgat cgtaaatgac aacggtcatc ttacaggtca
    17401 tatcactgac ggtatcggat ttatgtctgc cctgaaagat aatgatattg atgtgatcgg
    17461 aaagaaaatg accattgttg gtgcaggcgg tgctgccact gccatcgaga tccaggctgc
    17521 tttagacggt gttgccgaga tcacaatctt taaccgcaag gatgaattct gggatcgtgc
    17581 agtatccaca gtagagaaga tcaacacaaa gacatcctgc catgcagttc tttatgatct
    17641 ggcagatctt gataaactga aagctgagat ggatgacagt tttatctttg tcaatgctac
    17701 aggtgtggga atgaaaccac tggaaggaca gtccgttgtt ccggacaagt cttacttccg
    17761 tcctgagctg atcgttatag atgttcctta ctctcctctg gaaacaaaaa tgcgttccat
    17821 ggccaaggaa gttggatgca agacaatgaa tggtctggga atgatgttat tccagggttc
    17881 cgctgcattt gagttatgga caggcgaacc aatgcctatc gaacatatga aagagattct
    17941 tcacatctcc tatgatgact gatacctgat ggtatcttca gtaaagatat ctcatattgt
    18001 gatgcagaac agatcatttc actgatcttt ctgcacataa tatttgatat ataccgcttt
    18061 tcggcgtact gcaggagatg tactgatata ttactccgcg cagaatgtac atatcctgca
    18121 gtttgcttca aaaagctgtt gatcatgcgg ttatgttacg gttattctta taacagttcc
    18181 ataataatcc ggaactacta taatacaaca gaaaatatga ggataaacag atgaacacag
    18241 ttcaggtaaa aaacactgtg atcggcgagg gcagacctaa gatctgcgtt cccatcgtag
    18301 gaaaaacaaa aacagacatt ctcgaagaag ccaaaaagat cactactctt cctgttgatg
    18361 tagttgagtg gcgtgttgac tggttcgatg atgtctttgc tactgagaaa gtattagaaa
    18421 ccgctaaaga gcttcaggaa gttttaaaag acattcctgt tctccttaca ttccgtactt
    18481 ccaaagaagg cggtgagaaa gaaatttctg taaatgacta tgctgcttta aatattgcag
    18541 ctgctcagag cggttatgta gatttaattg atgtagaagc atttacaggt gatgaagttg
    18601 ttaagacaat catcaatgct gctcatgagg caggtgtaaa ggtaattgct tccaaccatg
    18661 atttctttaa gactccggag aaggaggaga tcatccgacg cctctgcatg atgcaggagc
    18721 tgggtgctga tatccctaag attgcagtaa tgcctacctg taagcaggat gttatcacac
    18781 tgctgtctgc cactctggaa atgtctgaga aatatgcaga ccgcccgatc attaccatgt
    18841 ccatggcagg aacaggcgtt gtaagccgtc taacaggtga gacattcggc tccgctctca
    18901 ctttcggtgc tgcttccaaa gcttctgctc cgggacaggt cggtgtacat gaattaaaac
    18961 aggtgctgga tatcattcac agcagcctgt gatctgttga tgaatgatgt gatatcagat
    19021 gttattcttg cctatagctg atatcactca tattcgtcaa cagattgtta cagaatttga
    19081 atttaataat tatgactcct taaaataata attgatgaaa accaagaaga acagccctga
    19141 atcccggctg ttcttcttgg ttttcgttta tattattttt tctcaaaggg attccagttg
    19201 gacaggaaga tattcagtcc gaagcctact gccagtgccc atgcagatgc ccatgcggtt
    19261 ccctgggttg cgaggactgc tgccataacg cctgcaatca tcttgtctct gtcgctctta
    19321 cagtaatcca taccaattct cgcacataca aacgcctgga acatcagagt aatggaagat
    19381 cctactccga agatcggacg gaagaagctt actacaggaa tgatcagcac acttaagaat
    19441 gtggccagtc tgaaagaagc cattcctccg agaagagact tcattgcttt ctttccttct
    19501 ttataacgca tggatacgga tacagtcatt ccaacccata acggaccgga aaggggagga
    19561 aatggtgcaa tgatggaaag gatcaggttt ctcagaccgc ttaccagatt ggaacggctg
    19621 gaattgaaat caatatactc atcatctctt gcgtgacgtg cctctgatac aagagtctct
    19681 gtagtaacaa aatcaccaaa tgcaataaca tagcacacca gtgccagcgg cagtgctttg
    19741 ataaacatag atgcaggagg aatccctacg ccaaaaatgc tcacctgatc aatgatatct
    19801 ttaaactgag gaatcttgat aaaagtacca atctccagtc ccggagcatc cagttctcca
    19861 accagaagtc ctactaccat tgcgataaga tatgggaaga gatttccata tcttgcaaca
    19921 agatcaagaa acttatttgt ttttctcttc tcctgatatt tgtcagagaa gctgatcagg
    19981 atcaggaggc ctacacctgc aacaatagcc agaggatatt tgtgcatatt tccgttctct
    20041 cccagctgcc ctgccataac tgttacaggt gccgcaagaa ggatacctcc ttttacagaa
    20101 ttggggactg catgaacaaa tttatccgcc agtctggtca cacccataaa gataaatacc
    20161 agacctacca acatctgcag tgcgatcatt gcctggattc tctcctctcc catagggaag
    20221 ccttccagaa atacgatggt tagaggcagt gtgggtgtga tccatcccgg tacaaccgga
    20281 tcacctagca gactgtgcag cagataaaga aatgtctcaa taattacaca gctccacgcc
    20341 agctcataag gaagccccag atactgctcc agataaggaa cagctgccag tgctgttacg
    20401 cccaggatca gaccctgaat gaactcaaca gattctatct tgtaatgtat gaatggaagt
    20461 cttatctgaa atggtccaaa ggggatgtag ggcagttcat tttctcttct ttgtgttctt
    20521 gtatttgcca tacagattct ccttttcaat aaattgttag attaattcta tatttcagct
    20581 tgtatattct atctttttgt taatttttag acaatccgga ttttaataaa atccaatccg
    20641 accggaaaaa atttgaagct tgtaacgtcc aaacgtatct tcagttggat tggattttaa
    20701 taatttttta tttcaaggcg tagaaaggag gcatagcggt agctacgaca cccgacaaca
    20761 acgcgaaaat aagaaattta gatgcgagat tattcaggaa atcaacttgt tggcacactg
    20821 ccttactgat ttctgttctt ctttacaaag agggcgagca ggataccgac gatggtcact
    20881 gccatgttca gaagaagaat cattctcgga gcactgcttc cgccaacttt ggtaatgtac
    20941 cctgcaaggc ttaagattgt gtagttcgcg atgctggatg cgatcattac cagtgaggtt
    21001 gctgttccct tattctcagg gaagaactct gctgtggtgg aaactgccag ctggagaaca
    21061 ccgcctgcac ctgcatatcc gatcacaaaa ccacctacca gacaaataaa cggagcctgg
    21121 ataaagtagc agagagccag cataattgtg gagattagcg gatagagaat caggacgcta
    21181 atctctttca gacctttttt gataaaagct gctgttgcaa ggatggcagt tgcagttccc
    21241 agggcataca gggactggat ctttgaagga tctgccatac cgtaggaacg ggcaagttcc
    21301 tgattacagt tcagccataa cataaaggtt gaggagctgg tgaatccaat cagaattgca
    21361 gcaatcgctg caggggaaat cttgtgtccg gatttcttct tatcagcttt agcctgtact
    21421 gccttctctc tcgccggaaa ggggagaatc aggatcagga ttccgtcaat gaggattgca
    21481 atacctgcta cgataaagat tgtcttatat gacatatttg cggatgctac gattccgatc
    21541 aggaatggaa gcaaaaactg gctcagacag atggagaatt ttgtaaacag gttggctact
    21601 gacggattgt ttacatagat ttccatacag gtcgggctta cacatgtgtc aaggaaggag
    21661 ttggcaattc ctccgattac agcaaatgca tatcccattg ccattgatgt agaattagcc
    21721 attccaaaga agtacgctac ataacagagc acaccgataa ttccgctcaa tcttcgtcca
    21781 tatttgtcag acagaggacc agagaaagga agagaaatca gacgtcccag tccaagtgct
    21841 gcaattacag atactaccat acttacatcc agtgtgccat cggccagggg cttcgcaccc
    21901 caggcagctg caaactcggg tttgtactgc cccaggatag aagcaccgat tccatggatg
    21961 aaataggtga aatatgctgc aagggaggtg aaaatgagca ttttgtttgt tttctgtttc
    22021 attttggtct cctaggttat tattacttgt tttcgttttc ttcctggaat ttctggtatt
    22081 tagctgttgg catttccagt cctgtgtaga gtttgtaagc tgcagctccc tgccataaca
    22141 gcattccttt tccgccgatt gcaagcttgc agcctgcttc tttggcttct tttaccattc
    22201 ttgtttcagc aggattgtaa acaacgtctg ctactacaag gtcagggcgg aacatggatt
    22261 tatctttgat cagagtaagc tcttcgtgag gtttcattcc tgcaagtgtt gcgtttacga
    22321 ggatgtctgc gtttgcaacc tcttctttca gttttgcctc atctgccaga tcaaatacag
    22381 aaactttaca atccggtgtt tctttgctca gtttctctgc tgtggactct gcacgtgcaa
    22441 agaatgggtc tttcggattg aagatagaaa tggattctgc accgtctaat gcacactgta
    22501 cctggattgc tgttgcagca ccgcctgcac cgagaactac catttttttg cctttcacat
    22561 caacgccatg ttcttttaag ttgcggacaa atccgatacc gtctgtgata tgtcctacta
    22621 atttgccgtc ttcattaacg attgtgttaa ctgcaccgat gattcttgct gcaggtgaaa
    22681 gctcatccat gtgttttgca gcttcgttct tgcatggcat agttacgttt gcgcctctca
    22741 ttttgaaaag acggattgca tccagagcag ccggaacctg gtcttccttg atgtcaaatg
    22801 ccatgtaagc atagtcaagg ttatgatgac ggaagctgaa gttatacatt gccggtgatc
    22861 ctgagtgtcc taccgggctt ccgataagtg ccattaatcc tgttgttcct ttaattctct
    22921 gttccatttc ctttttgcct cctgaatttt tttgtaaaat cattttcaag ctgctgtccg
    22981 ctgataatat catacagcgt ctcttaactg caactataaa acgaataaat tataagattc
    23041 gaaattcgct gatttactgc gtaaatcgct gctttctcat gtttggcggg tcccaggttc
    23101 aaaaatctta tcgtgcaagc acgaacgact ttttgaactt ttgaccctga tatcatcata
    23161 atgtggaagc tacctcatac gcttctttcg tagcatcaag tgctcttctt gcgcgggtgg
    23221 catcgccgat cacataggta tccggtacga tagctttgat ctcttcgccg aatgggttgt
    23281 agtttctgaa tcccatggaa aggatgacag aatcatatcc tctggattca tgtctctgtc
    23341 cgtctgctgt ctcgtactct acgccgtcct catagaattt gcataccttt gcacctgtga
    23401 tctctttgat cttgtaatct tcgaaatctt tcatcaggta aactctatgc tcgtggatca
    23461 cgtcggcacc tacagtgtct ctgaactcaa tgactgttac atcatggttc tgctcaccga
    23521 ggaatgctgc tgtctcgcat cccaccattc cgccacctac aaccagtact ttctttcctg
    23581 ctgctctctt tccgtcaagg agatcagagc catggataat tgcaggattg tcgatacctt
    23641 cgatcggaag gatcagtgtt ctggaaccgg aagcaacaat tacgctgtct ggtttctctt
    23701 ccctgataag atccagagtt acttcctgat tcattttaat tgttacgcct gctttctggc
    23761 agcgtacgat atagctgcgg atcatgtttg tgatgtcgcc ttttcccgga ggataagcag
    23821 caagacgcat gtttccgcca agtttatcac ttgcttcata aagtgttacc tgatgacctt
    23881 tttcctgtgc gataaatgca gcgcaaagac ctgcaacacc gccaccgatt accattactt
    23941 tcttagcttt ttctgcagga acaatgccct cagcttcatg tccaaggaat gggtttacaa
    24001 gacagcatac agggtttcct gcatacatgt ttgccacgca gccctgaaga catgcgatac
    24061 atgggatcat atcctccagt ctttcttcct gcgcttttaa tggcatataa ggatctgcaa
    24121 ggctctgacg tccgaatgca accaggtcac agcgtccttc ttttaccatt aattccgcaa
    24181 actgcggttc tgtataacgt cctactgtga tcaccgggat agatacggca cgtttgatct
    24241 cttctacctg agaagcggag aaaccgccgt gtgtaactgt cggtgcccac ataaattcat
    24301 cgcggatgtg aacagctctg gatacatgga tggcatccag tccgcatcct tccagatatg
    24361 cagcgatcgc agcactgtca tgc
//
