LOCUS       c00060_gnlPro..        16678 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AKDGHAFL_60.
ACCESSION   c00060_gnlPro..
VERSION     c00060_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 01:15:03
            Original ID  :: gnl|Prokka|AKDGHAFL_60
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 20512
            Orig. end    :: 37190
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16678
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[30512:33505]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12993
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16678
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16678
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(543..1907)
                     /locus_tag="ctg60_17"
                     /transl_table=11
                     /translation="MATSIYAKPIKAKTILKFTLPTVLMMVFMSLYTVVDGIVVANCVG
                     SDALSAINIVYPFTLVFMAVGLMFSTGSNAIIAKKMGEGKQEEANRLMSGVAITATVIS
                     VIIAVLFTIFAEPMYMMFGSNEKILPYCIDYGSVMIPYGFVMCWQMLNQSYLVTADKPH
                     IMLVFSILSGCTNIVLDILFMAVWDFGIIGAGLGTIIGMAVGAIPLLLFFNKKQTLHFG
                     KPEFKVSEILFAMANGSSEAVTNLSTAVTTALFNIQMMHFAGAKGVAAISAILYIHFIF
                     TAVSFGFTSGVSPVISFNYGAQNHEKLQKLFKLCIKITLIISVAMITASEFFAEPLVGI
                     FSAGNEKIQQIALSGFRIFAINYLLCGMNIFASGLFTALNNGKISAVISVARTLVFECA
                     AMLILPMFIGINGVWSALPVAELCAVAISVTFIIANAKKYHLVGVPPHPVRADSL"
     CDS             1957..2694
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg60_18"
                     /sec_met_domain="HAD_2 (E-value: 3.4e-38, bitscore: 122.3,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LYHNFVAITTDLSFFVKYAIIYRLKSEKRGGFMFKGAVFDMDGLM
                     IDSERLVYSIWQEMLDEDGKEFNLDIFKKTIGLRSEDSYEYYKSVYGDDFDYPAYKAES
                     RIRYFKRIEKNGVPVKKGLYEIFDYLKSVGCKISLATSTSSQTALKIMKKINLYDKFDA
                     FVCGDDVKNGKPDPEVFLIAAKKLGLEPVDCVAFEDSINGIKSAHSAGMTTVMVPDLSE
                     PTDEIKPMIDFLCTDLSEAIKHL"
     CDS             3082..6642
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EKR"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg60_19"
                     /sec_met_domain="PFOR_II (E-value: 4.9e-19, bitscore: 59.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.9e-82, bitscore: 265.2,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 8.5e-33, bitscore: 104.7,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.7e-14, bitscore:
                     43.0, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_7 (E-value: 3.3e-11, bitscore: 34.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.3e-07, bitscore: 21.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 2e-09, bitscore: 28.2,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00011, bitscore: 13.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 7e-21, bitscore: 64.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LARKMKTMDGNSAVAHVSYAFTDVAAIYPITPSSVMADLTDKFSA
                     QGAKNLFGRQVQVTEMQSEGGASGAVHGSLAAGALTTTYTASQGLLLMIPNMYKMAGEL
                     LPGVIHVSARALTSHALSIFGDHSDIYACRQTGYAMLCSNNPQECMDLAAVAHLAAIEG
                     RVPFLHFFDGFRTSHEIQKIEEWDYADLADMLNWDAVEAFRRRALNPEHPVTRGTAQND
                     DIFFQAREACNKYYDAVPEVVVKYMDKVNAKIGTDYKPFNYYGAEDAEHVIVAMGSVCD
                     CTEEVVDYLNAAGEKVGLLKVHLYRPFVADYMLRELPKTVKTISVLDRTKEPGSIGEPL
                     YLDVLAAINGSDFAGVKVYTGRYGLGSKDTTPGDIIAVYRNAESETPKRRFTIGIVDDV
                     TNLSLPIVENPDTTPKGTHSCKFWGLGADGTVGANKNSIKIIGDNTDMYAQGYFAYDSK
                     KSGGLTVSHLRFGKTPIKSTYYISKADFVACHNPSYVDKYDIVDDLKEGGSFLLNCPWD
                     TEELSERLPGKMKKILAERHINFYTIDGIKIGKEIGLGGRINTVLQSAFFKIADIIPAD
                     KAKELMKAAAKKSYMKKGQAIVDMNYAAIDRGMEDLKKVEIPADWANAVDNLVADKAEG
                     NGALVEYVNEILKPVNAYKGNKLPVSTFMDHVDGTAPNGSAAYEKRGIAVDVPEWNPEN
                     CIQCNRCAIVCPHAVIRPVAMTADELAKAPEGTKSLPMMGLKDLNFVMTVSTLDCTGCG
                     ACAQVCPGKKGAKALTMQSIDSQRPKQAVFDYALTLEDKPEVHEKFKFTTVKGSQFKQP
                     LLEFSGACAGCGETPYAKLVTQLFGDRMFIANATGCSSIWGASAPATPYTKNKKGYGPA
                     WQNSLFEDNAEFGLGMALGQKAIRNRLIEYVEGIQKDTDSADLKTACQNYLDTVTDSTS
                     SRPATDALIAELEKNTEDAKVGELVKKTLVDKDELAKKSMWIFGGDGWAYDIGFGGLDH
                     VIASGENVNILVFDTEVYSNTGGQASKATPVGSVAQFAAAGKAVKKKDLAAIAMSYGYV
                     YVAQCAMGADNNQVLKAMVEAESYNGPSLVICYAPCINHGIKGGMGIAQLEEKKAVEAG
                     YWNIFRYDPRLADEGKNPFMLDGKAPSASYRDFIMGEVRYNSLTRSFPERAEKLFEKAE
                     KVAADKYAHLEKLASLPDAE"
     CDS             6765..6944
                     /locus_tag="ctg60_20"
                     /transl_table=11
                     /translation="MVSGVPPQSFREDSLVNERVNMPECRYAMFVQICMGEHGVKCNMV
                     TVRPYIITVALQHL"
     CDS             complement(7151..8338)
                     /locus_tag="ctg60_21"
                     /transl_table=11
                     /translation="MKKKIFILLLCVVLIATCILCGVTGIFGNDSQNSPKPQTPDTAVT
                     ENMTFPSTVDSLTLKVGESKLIELSSEKAKSVTKWTSSDSKIVTVDDGGRVDALKEGTA
                     LISAILKDKSKSEFQVTVAKSTMKKQQSYSTCITANLDKLENNKRNTAKNLYAIKVNRT
                     ANCVTVYTYDEKGKYTIPVRAMICSTGLDNSTITGDYTIGIKSKWLFLVGDVFGRYISG
                     ISGDYLFHSVPYYSMSEEDLELEEFNKLGEQASQGCVRLAVSDAKWVYDNCPTGTNVSI
                     YDDAENAGPLGKPGAIKITDFTNKWDPTDSNKKCPYSKATPIISGANDYTIKSGGKFYA
                     LAGVTAVDTCGNDITSNIEVFGNVITTRKGKYKVTYSVTDVLKRTSSVTITVTVQ"
     CDS             8728..9039
                     /locus_tag="ctg60_22"
                     /transl_table=11
                     /translation="MHHKGRNRHHYEYWNDYNPKTKQIENVEMPVKYVIEMFCDRVAAS
                     KIYNGKNYTDGAPFTYFCRIRGKHRMHPNTEALLEKLLVMLRDEGEEKTFAYIRSMKK"
     CDS             9243..9734
                     /locus_tag="ctg60_23"
                     /transl_table=11
                     /translation="MKTDRVITAMIEYFGSDKKRIHHFLKVYSFAKTIGESENLLPDDQ
                     ELLEISAIVHDIGIKVSEEKYNSSAGKYQELEGPHEAEKLLAALGYEKTFIDKVCYLVG
                     HHHTYGNIDTLPYQILVEADFLVNLYEDDSSRSAAEQAYDKIFRTNTGKNLLKIMFLIP
                     "
     CDS             10001..12238
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg60_24"
                     /sec_met_domain="Gly_radical (E-value: 2.8e-41, bitscore:
                     131.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 4.6e-272, bitscore:
                     894.5, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEWTNFAGGKWESDIDVRDFIQKNYTPYDGDQSFLEGPTEATD
                     KLWGELKELQKEERAKGGVLDMETEVVSGITAYGAAYLDKDLEKVVGLQTDKPLKRAFM
                     PYGGIKMAEQSCQMYGYTPSPKLHEIFTKYHKTHNQGVFDIYTPEMKLARHNKILTGLP
                     DTYGRGRIVGDYRRVALYGIDRLIEGKKEDFAETNRQGMRRGDFQLREEIADQIRALND
                     MKEMALSYGFDISQPAKNAAEAVQWLYFGYLAAIKTQNGAAMSVGRVSTFLDIYIERDL
                     ENGTLTESQAQELVDHFVMKCRMVKFARIESYNQLFSGDPVWATLEVAGLGIDGRSMVT
                     KNDYRFLHTLENMGPSPEPNLTVLYSSRLPENFKKYAAHISVTTSSIQYENDDVMRPVW
                     GDDYSICCCVSATQTGKEIQFFGARANLAKCLLYAINGGIDEKTKMQVGPEYTPITSEY
                     LDYDEVIKKYDTMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTDVRRTFATGIAG
                     FSHVVDSLSAIKYAKVKVIRDDDGIAVDFETEGDFPRYGNNDERADKIAVDLLKTFMAK
                     LKYCHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQNGLLA
                     SLNSVAKLPYEYALDGISNTQTINPGALGHNDDERVDNLVNVMDGYFDQGAHHLNVNVF
                     GTEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             12238..12993
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 76.2;
                     E-value: 1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg60_25"
                     /sec_met_domain="Radical_SAM (E-value: 2e-30, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNAVKGFVHSIETFGSVDGPGVRFVIFLSGCAMRCQFCHNPDT
                     WKHDENTVEYTADELLNKALAYRPYWKNKGGITVSGGEPLLQIDFLLDLFKKAKKQGVN
                     TCIDTSANPFTTKEPFYSKWKELMEYTDLLLLDIKHIDNEQHKILTGQPNTNILEMARQ
                     LSDMGKPVWIRHVLVPERNDKDEYLFRLADFIRSLKNVERVEVLPYHTLGVYKWKALGY
                     DYPLEGINPPTKERVKNAEMILNGEKTRD"
     CDS             13519..13737
                     /locus_tag="ctg60_26"
                     /transl_table=11
                     /translation="MDKNKKLFYTIIGAISALAAATAAFLALKKHRCAEQKLIEEIDDI
                     VSEKEPEEAAKEEPQAEVTADELAEEE"
     CDS             14312..16444
                     /locus_tag="ctg60_27"
                     /transl_table=11
                     /translation="MKKIQKKLSVVLAVMMVLCMFTALPFSASAAETSEETSAGNKINV
                     TSNVTDPVSYDYNAQTEQVVVTYLLKADHMIVDTQSSLTYDSKVLKLASTTTTNTKKKV
                     FPVFQSSIVWNTSITNQVYFNCSSLDLFNFKSENVYCTFTFDVVGSGDTTVNLNVDYLT
                     GTEAESYDDFFESEKKDIDYIYDSANKVEGAAFTAKAVLVQGEEPTTAPQPTTVTQPTT
                     ATQPTTAPATKPTQPATEPTTTPSGDGATIKFAAPTSQASRYNWSKPVLFYGNTQSVDK
                     STKLSMTATSEKYYTTEVGSNTLLTTNGWTVYELKISKDQAAAINSSKFVGFATANGVN
                     RTTLVSGSNVLKAGVDTYTAKYGTTANTVAALDGKTFVIRDSAYGATSSVSFVGYWVSD
                     FVTVRAAAPLAATSYSTWDNVDLYYGNTTAFDSMTKLSMINTGDTTKVSSLNGNMTIKT
                     GRWYIYAITLDKATASAVENAKYVGFNKTDAVNRTAILKNVLFAKTNTFDGNYNSKART
                     LSELDGQLFVIKGMTAKSSSVATYTGEWETKDVYTQGKDDTVTLYFAAPKGVKNYANWD
                     TGVQLYYSNDNVYTKAERIDMKKVNETKKVTVDSSKLKTLKSGNWDVYSVTLTVDQIKA
                     IDNCQSVGFVKKGSFNRTAYTAYRNICKASKMDGNSTYSGVRESIETFDGYMFVINSCY
                     TPSNENISLTGSWVVK"
ORIGIN
        1 ggttgctaag tatgttacag acttcggaac agacgatatt ctcggtgaag agaatattat
       61 ctgcctccca cacctcggtg catcaactcc cgaaagtgaa gaaaattgtg ctgttatggc
      121 ttgtgatcag gttaaggagt atctcgagaa cggtaacatc atcaactccg taaactatcc
      181 tgcaatttca cttgcaagaa caaatgctga cgatacccgt ttctgcgttg ctcacaagaa
      241 tgttcccgag cttctcaaga aggttctcac acagatcagc ggcaatgttg aaaatatgct
      301 ttcaaagagc cgtggcgact atgcttacac aattattgat gttgcaggcg ccggtgcaga
      361 tgaccttgca aaaatcgcag cagttgacgg cgtaatcaga gttcgtgcaa tctgatttcg
      421 attttaattg aactttaatt gttgtaaaaa attatccgag cattgttttg atgctcggat
      481 tttttgcgtt tatttgtaca aatggttaca atgctacact tgggcataat atgtttttga
      541 tatcacaaac tgtctgcacg aacggggtgc ggtggtacac cgaccagatg gtattttttt
      601 gcattggcaa ttataaatgt tacggaaatt gcaacggcac acaattctgc aacgggcaat
      661 gccgaccata caccgtttat gcctataaac atcggcaaaa tcagcattgc ggcacactcg
      721 aaaacaagtg ttcttgcaac tgaaattacg gctgaaatct tgccgttgtt gagtgcggtg
      781 aaaagtcccg atgcgaaaat attcattccg cacaacagat aatttattgc aaaaattctg
      841 aatccgctga gtgcaatctg ctgaattttt tcgttgcctg ccgagaaaat tccgacaagc
      901 ggttctgcaa aaaattcaga tgccgtaatc attgcaaccg aaattatcag cgtgattttt
      961 atgcataatt tgaacagctt ttgcagtttt tcgtgatttt gtgcgccgta gttaaagctg
     1021 atgacgggtg aaactcccga agtgaatcca aacgaaaccg cagtgaaaat aaagtgaatg
     1081 tacaaaatag cacttatagc cgcaacgcct tttgcgcctg caaagtgcat catctgaatg
     1141 ttgaacagcg ctgttgtcac ggctgttgaa agatttgtca cagcttctga cgagccgttt
     1201 gccatagcaa agaggatttc acttaccttg aattcaggct tgccaaagtg cagagtctgc
     1261 tttttgttga aaaagagcaa aagcggaatt gcacccacag ccattccgat gattgtgccg
     1321 agtcctgcac cgattattcc aaaatcccac acagccataa aaagaatgtc aagcacaatg
     1381 tttgtgcaac ccgacagtat cgagaaaaca agcatgatat gtggcttgtc tgctgttaca
     1441 aggtacgatt ggttgagcat ctgccagcac attacaaagc catacggaat cataacgctg
     1501 ccgtagtcaa tgcagtaggg gagaattttt tcgtttgagc cgaacatcat gtacataggt
     1561 tcggcaaaaa ttgtgaacag cacagcaatg ataacagaaa tgaccgttgc cgtgattgca
     1621 acaccggaca taagtcggtt tgcttcctcc tgtttgcctt ctcccatttt ctttgcgatt
     1681 atagcatttg agcctgttga aaacattaag cccacagcca taaatacgag cgtgaacgga
     1741 tatacaatat tgattgcgga caatgcgtca cttccgacac agttcgcaac aacgattccg
     1801 tcaacaactg tgtaaagtga cataaaaacc atcataagaa cggttggcaa agtgaacttc
     1861 agaatcgttt ttgccttaat aggttttgca taaattgatg ttgccataaa atttcctcac
     1921 cctcaaattt atatttttca cagaccattc aaacgattgt atcataactt tgtcgcaatt
     1981 acaaccgatt tgtctttttt tgtaaaatat gctattatat acagacttaa aagcgaaaaa
     2041 aggggcggtt ttatgtttaa gggcgcagtt tttgatatgg acgggcttat gattgacagc
     2101 gaaaggcttg tttattcaat ctggcaggaa atgcttgatg aggacggcaa agagtttaat
     2161 cttgacattt tcaaaaagac aatcggactt cgcagtgagg attcctacga atattacaag
     2221 tcggtttacg gcgatgattt tgactatcct gcttacaagg cggagtcgag aatccgctat
     2281 tttaagcgta tcgaaaagaa cggtgtgcct gtaaaaaagg gcttgtacga aatttttgat
     2341 tatttaaaat cagtcggttg taaaatttcg cttgcaactt caacctcgtc acaaacggct
     2401 ttgaagatta tgaagaaaat caatctctat gataaatttg acgcattcgt gtgcggtgat
     2461 gatgttaaaa acggcaaacc cgatcccgag gtttttttga ttgccgcaaa gaagctcggt
     2521 cttgagccgg tggactgcgt tgcgtttgag gacagcatta acggcataaa atctgcacat
     2581 tccgcaggta tgaccacggt tatggttccc gatttgtcag agccgacaga cgaaattaaa
     2641 ccgatgatag attttttgtg tacggattta agcgaagcga taaagcattt ataaattgaa
     2701 aattacggcg agccgccgtt cccaattcgt gtagatagtt tgtaatgtca aaaaacaaat
     2761 tatgtccgag cgaaacattg caaccgtttg tacaaatagc caaaaccttt gttgttgatt
     2821 tttaaaaaat caacaacaaa gtattttgac aggaacaagt aaatataaaa aacttttttg
     2881 taaaaaacga aacaaaaata tatatcctgc tttgaatttc ttgtgtaaaa cactttacaa
     2941 atcggtgttt aagtgataaa atttaagatg atacaaagta tccgtaccgc ttgttgattt
     3001 acggtgcgta attaacgggt atcgaaaatt tatgcggcat catttccttt gccgctttga
     3061 ttaaaaagga ggacgattcc attggcaaga aaaatgaaaa ctatggatgg taacagcgca
     3121 gtagctcatg tttcttatgc gtttaccgat gttgcggcta tctatcctat tacaccttct
     3181 tccgtaatgg ctgaccttac cgacaagttc tcggcacagg gtgccaagaa ccttttcggc
     3241 agacaggttc aggtaacgga aatgcagtcg gagggcggcg catcaggtgc tgttcacggc
     3301 tcactcgcag caggtgcttt gaccacaact tacacagcat cacagggcct gctccttatg
     3361 attccgaata tgtacaagat ggcaggcgag ctccttccgg gcgttattca tgtatcagcc
     3421 cgtgcgctca caagccacgc actttctatt tttggtgacc actcagatat ctacgcttgc
     3481 cgtcagacag gttatgctat gctttgttca aacaatcctc aggaatgtat ggaccttgcc
     3541 gctgttgctc accttgcagc tattgaaggc agagttcctt tccttcattt ctttgacggt
     3601 ttcagaactt ctcacgaaat tcagaagatt gaggagtggg attacgcaga cctcgccgat
     3661 atgcttaact gggatgcagt tgaggctttc cgtcgtcgtg ctcttaaccc tgagcatcct
     3721 gtaacaagag gtactgctca gaacgacgat atcttcttcc aggcaagaga agcttgtaac
     3781 aagtattatg acgcagttcc cgaagttgtt gttaagtaca tggacaaggt taatgctaaa
     3841 atcggcactg actacaagcc gttcaactac tacggtgcag aggatgcaga gcatgttatc
     3901 gttgctatgg gttctgtctg cgactgtacg gaagaagttg tcgattacct caatgccgca
     3961 ggcgaaaagg tcggtcttct taaagttcac ctttacagac ctttcgttgc cgactatatg
     4021 ctcagagagc ttcctaagac tgttaagaca atctctgttc ttgacagaac aaaggaaccc
     4081 ggttcaatcg gcgaacctct ttatcttgat gttctcgccg ctatcaacgg ttcggacttt
     4141 gcaggtgtaa aggtttacac aggcagatac ggtcttggct caaaggatac aacacccggc
     4201 gacatcatcg ctgtttacag aaacgctgaa agcgaaacac ctaagagaag atttacaatc
     4261 ggcattgttg atgatgttac aaacctctca cttccgattg ttgaaaatcc cgatacaact
     4321 ccgaagggta cacacagctg taagttctgg ggtcttggtg ctgacggtac tgtcggtgct
     4381 aacaagaact caatcaagat tatcggcgat aacaccgata tgtacgctca gggctacttt
     4441 gcatatgact caaagaagtc aggcggtctt acagtttctc accttcgttt cggtaaaact
     4501 cccattaagt caacatacta catttcaaag gcagactttg ttgcctgtca caatccgtct
     4561 tatgttgaca agtacgatat tgttgatgac cttaaagaag gcggttcatt ccttcttaac
     4621 tgcccgtggg atacagaaga gctttccgag cgtctcccgg gtaagatgaa gaagattctc
     4681 gctgaaagac acatcaactt ctacacaatt gacggtatca agatcggtaa ggaaatcggt
     4741 cttggcggtc gtatcaacac ggttcttcag tcagccttct tcaagattgc agatatcatt
     4801 cctgccgaca aggctaagga gcttatgaag gctgccgcta agaagtcata catgaagaaa
     4861 ggtcaggcta tcgtagatat gaactacgcc gctatcgacc gtggtatgga agacctcaag
     4921 aaggttgaaa ttcctgctga ttgggctaat gctgttgata atttagttgc cgacaaggca
     4981 gagggtaacg gcgctctcgt tgagtatgta aacgaaatcc tcaagcctgt aaatgcgtat
     5041 aagggtaaca aactccctgt ttcaacattt atggatcatg ttgacggtac tgctcctaac
     5101 ggttctgccg cttatgaaaa gagaggtatc gcagttgatg ttcccgaatg gaatcctgaa
     5161 aactgtattc agtgtaacag atgtgcaatc gtatgtcctc acgctgtaat ccgtcctgtt
     5221 gccatgacag ccgatgagct tgcaaaagct cccgagggta caaagagcct cccgatgatg
     5281 ggacttaagg acctcaattt tgtaatgaca gtttcaacac tcgactgtac gggttgcggt
     5341 gcttgtgctc aggtttgtcc gggtaagaag ggcgctaagg ctctcacaat gcagtcaatc
     5401 gactcacagc gtcctaagca ggcagtattt gactacgctc tcacacttga agataagcct
     5461 gaagttcacg agaagttcaa gttcactaca gttaagggca gtcagttcaa acagccgttg
     5521 cttgaattct caggcgcttg cgcaggctgc ggtgaaacac cgtatgcaaa gcttgttaca
     5581 cagcttttcg gtgacagaat gtttatcgct aacgcaacag gctgttcatc aatttggggt
     5641 gcatctgctc ctgcaacacc ttatacaaag aataagaagg gttacggtcc tgcttggcag
     5701 aactcactct ttgaagataa cgcagagttt ggtcttggta tggctctcgg tcagaaggct
     5761 atccgcaaca gacttatcga gtatgttgag ggtattcaga aggatacaga cagcgctgac
     5821 ctcaagacag cttgtcagaa ctatctcgac acagtaacag attcaacttc aagccgtcct
     5881 gcaacagacg ctcttatcgc tgaactcgaa aagaacacag aggatgcaaa ggttggcgaa
     5941 cttgttaaga aaacactcgt tgacaaggac gaacttgcta agaagtcaat gtggatcttc
     6001 ggcggtgacg gctgggctta cgatatcggc ttcggcggtc ttgaccatgt aatcgcatca
     6061 ggcgaaaatg ttaatatcct cgtattcgat accgaggttt attctaacac aggcggtcag
     6121 gcttcaaagg ctactcctgt aggttcggtt gcacagtttg ccgccgcagg taaggctgtt
     6181 aagaagaaag acctcgccgc tattgcaatg agctacggct atgtttatgt tgcacagtgc
     6241 gctatgggtg ctgacaacaa tcaggttctc aaggctatgg ttgaggctga aagctacaac
     6301 ggtccgtcac tcgtaatctg ctacgctccg tgtatcaacc acggtatcaa gggtggcatg
     6361 ggcattgctc agcttgagga gaaaaaggct gttgaggcag gttactggaa catcttccgt
     6421 tacgatcctc gtcttgcaga cgaaggaaag aatccgttca tgcttgacgg taaagctcct
     6481 tctgcatcat atcgtgactt catcatgggc gaagttcgtt ataactcact cactcgttca
     6541 ttccccgaaa gagcagaaaa actctttgaa aaggctgaaa aggttgctgc tgataagtat
     6601 gctcaccttg aaaagcttgc aagccttccc gatgccgagt aattttggct aaagcttgta
     6661 caaagtgaat atgtgaataa ataaaaaatt ctcccgaata tggcatttgc cgtgttcggg
     6721 agattctttt ttaattgaaa atgtaaaatg gaaaattgaa aattatggtc agcggtgtgc
     6781 caccgcagtc ctttcgggaa gacagtcttg ttaatgagag agtgaatatg cccgagtgta
     6841 ggtatgcaat gtttgtacaa atctgtatgg gcgaacacgg tgtcaagtgc aacatggtaa
     6901 cggttcgccc atacattatt acagttgctt tgcagcattt ataaaatttg tattaatata
     6961 tagtctgtgc cgttgcttgt gggcgaatga tatccgcccc aacagataaa caacaacttt
     7021 catatataaa aaacagtcgg gaagacgatg ttttgcattt tgcaagccgt cttcccgaca
     7081 ttcattttcc attttcaatt ttccactttc aatttaaaag ctccgctcgg agaacagtgg
     7141 cgcaccgtgt ttattgcacc gttaccgtaa tcgttacgct tgatgttctt ttaagcacat
     7201 cagtgactga atatgttacc ttgtacttgc cttttcgggt ggttatcaca ttgccgaaaa
     7261 cttcgatatt cgaagttatg tcgttgccgc aggtgtcaac ggctgttact cctgcaaggg
     7321 cgtaaaattt gccgccgctt ttgattgtgt aatcgtttgc gccgctgatt attggtgttg
     7381 ctttggaata cgggcatttt ttattgctgt ctgtcggatc ccatttgttg gtgaaatcgg
     7441 tgattttgat tgcacccggt tttccgagag ggcctgcatt ttctgcgtcg tcatatatgc
     7501 ttacattcgt gcctgtgggg cagttgtcat aaacccactt tgcatccgaa accgcaagtc
     7561 ttacgcatcc ttgtgatgcc tgttcgccaa gcttgttgaa ttcctcaagc tccaaatctt
     7621 cttcgctcat tgagtagtag ggaacggagt ggaaaagata atcgcccgaa attccgctga
     7681 tgtatcttcc gaaaacatcg cccacaagga aaagccattt ggacttgatt ccgattgtat
     7741 agtcacctgt gattgtcgaa ttgtcaagac ctgtagagca aatcatcgcc cttacgggaa
     7801 ttgtgtactt gcccttttcg tcatatgtgt aaaccgtcac gcagtttgcc gtgcggttga
     7861 ccttgattgc gtacaggttt tttgccgtgt tacgcttatt gttttcaagc ttgtcaagat
     7921 ttgccgttat acaggttgag tagctttgct gttttttcat ggttgatttt gccaccgtaa
     7981 cctgaaattc cgactttgat ttgtctttta aaatggcaga aatcagagcc gtaccctctt
     8041 tgagagcgtc aacccttccg ccgtcatcaa cggtaacaat tttactgtcc gagcttgtcc
     8101 atttggtaac ggattttgct ttttcggatg acagttcaat aagctttgat tcgcctactt
     8161 ttaatgtgag cgaatcgacc gtgctcggaa atgtcatatt ttcggttact gccgtatcgg
     8221 gcgtctgcgg ttttggagaa ttttgagaat catttccgaa aattcccgtc acaccgcata
     8281 atatgcaggt tgcaatgagg acaacacaaa gtaaaagaat gaaaattttc tttttcatag
     8341 attacctatc cttatagaat ttaacattaa atggttacaa aattttaacc tttgtatatt
     8401 ataacttttt ttcgacaatc ttgcaagtgc tattttaaat cggcgagaaa tgtggtaaaa
     8461 tgacagtcgg agaatgtttt gtattttcca aactaacaat tcatggtgat aattatggca
     8521 catccgatta aacatttcag aacaataacc cgtcacaggc acaaggtaat tgccaactgt
     8581 gcaagggcag gaattctcag acagggatta atacacgatt tgtcaaagta ttcgcctaca
     8641 gaatttattc cgggtgcaaa gtattttcag ggcacgagaa gtcccaatga aaaggaaaga
     8701 gagctgtacg gctattcaca ggcgtggatg catcacaagg gcagaaaccg tcaccattac
     8761 gaatactgga acgattacaa cccaaagaca aagcagattg aaaatgttga aatgcctgta
     8821 aaatatgtta tcgaaatgtt ctgcgaccga gttgccgcaa gcaaaatcta caacggcaaa
     8881 aattacacgg acggcgctcc gtttacatat ttttgcagaa tcagaggcaa acaccgtatg
     8941 caccccaaca ccgaggcttt gcttgaaaaa ttattggtta tgctgagaga tgagggtgaa
     9001 gaaaagacat ttgcatatat aagaagtatg aaaaagtgat tgtttgtgcg aatcctcccg
     9061 tctgaaatat agtcgcaaag ctttgtacat aaatgtactg cctattgctc gttatttcag
     9121 acagcgcttt gctcccttta tccgccacag gcggcggtcg caaggctacc cctacagaat
     9181 tgcacaaaca aaaaactatc tacacgaata gtgtacggcg gctcgccgta aggagtgata
     9241 atatgaaaac cgacagggtt ataactgcta tgattgaata ttttggaagt gacaagaaaa
     9301 gaattcacca ttttctcaag gtttattcat tcgcaaagac aatcggtgaa agtgaaaatc
     9361 ttttgcccga cgatcaggag cttcttgaaa tctccgcaat cgttcacgac atcggcataa
     9421 aggtgagcga agaaaagtac aattcgtctg caggaaagta tcaggaactt gaaggtcctc
     9481 acgaggctga aaagttgctt gctgctctcg gctacgaaaa aacatttatt gacaaggttt
     9541 gttaccttgt gggacaccat cacacctatg gaaatattga tactttgccg taccaaattt
     9601 tggtagaggc agacttcctt gtgaaccttt acgaggacga ttcaagccgc agtgcagcag
     9661 agcaggcata tgacaaaata ttccgcacaa atacaggaaa aaatctgctg aaaataatgt
     9721 tcctcatacc ctaaaattgt actcatttac catagcgctt tgagtgtgaa aaagtggtgt
     9781 aaaaagtatc tcaaaatgct tgacaacgcc cttaaaaagt gttattttaa tggtgttggt
     9841 tatatgatta taaaagtgaa taaatgacag aatacaagga tgtatgacga ttttttcaag
     9901 gagctgacct taccgggcgt ctgcttggaa ttgagtcggc atttttttgt gtcatataca
     9961 aaattcagta ttaattatca ttatcggagg ttttacagta atgagagaag aatggacaaa
    10021 ttttgcaggt ggcaaatggg agtccgacat tgatgtcaga gacttcattc agaaaaacta
    10081 cacaccttat gacggcgacc agtctttcct tgaaggtcct acagaagcta cagacaagct
    10141 ctggggcgag ctcaaggaac tccagaagga agaaagagcc aagggcggcg ttcttgatat
    10201 ggaaactgag gttgtaagcg gcatcacagc ttacggcgct gcatatcttg ataaagacct
    10261 tgaaaaggtt gtaggtcttc agacagacaa gcctctcaag cgtgcattta tgccttacgg
    10321 cggtattaaa atggctgagc agtcatgcca gatgtatggc tacactccaa gccctaaact
    10381 ccacgaaatc tttacaaaat atcacaagac tcacaaccag ggtgtattcg atatctacac
    10441 tcctgagatg aagcttgccc gtcacaacaa gattcttaca ggtcttcccg acacatacgg
    10501 cagaggcaga atcgtcggtg actacagaag agttgctctt tacggtattg accgtcttat
    10561 cgaaggcaag aaagaggact ttgcagaaac aaaccgtcag ggtatgagaa gaggcgactt
    10621 ccagcttcgt gaagaaatcg ctgatcagat tcgtgctctt aacgatatga aggaaatggc
    10681 actttcttac ggctttgata tttcacagcc tgctaagaac gctgcagagg cagttcagtg
    10741 gctctacttt ggctatcttg ctgctatcaa gactcagaac ggcgctgcaa tgagcgttgg
    10801 tcgtgtatca acattcctcg acatctacat cgagcgtgac cttgagaacg gtacacttac
    10861 agaatcacag gctcaggaac tcgttgacca ctttgttatg aagtgccgta tggttaagtt
    10921 tgcaagaatt gagtcttaca accagctctt ctcgggcgac cctgtatggg ctacactcga
    10981 agttgcaggt cttggcattg acggccgttc aatggttaca aagaacgact accgtttcct
    11041 ccacacactt gagaatatgg gaccttcacc tgagccaaac ctcacagttc tttattcttc
    11101 aagacttccc gagaacttca agaagtatgc tgctcatatt tcagttacaa caagctcaat
    11161 tcagtacgag aacgatgatg taatgcgtcc tgtatggggc gatgattact caatctgctg
    11221 ctgcgtatcc gcaacacaga caggtaagga aatccagttc ttcggcgcaa gagctaacct
    11281 tgctaagtgc cttctctacg ctatcaacgg cggtattgat gaaaagacaa agatgcaggt
    11341 tggtcctgaa tatacaccta tcacatcaga gtaccttgat tatgacgaag ttatcaagaa
    11401 gtatgacaca atgatggatt ggcttgctca cctctatgta ggcacactta acatgattca
    11461 ctacatgcat gataagtact actatgaggc agcagaaatg gctcttatcg atacagatgt
    11521 aagaagaaca tttgcaacag gtattgcagg cttctcacat gttgttgact cactcagcgc
    11581 tattaagtac gctaaggtta aggttatccg tgacgatgac ggcattgctg ttgactttga
    11641 aacagagggt gacttcccaa gatacggtaa caatgacgag agagcagata agattgccgt
    11701 tgatcttctt aagacattta tggctaagct taagtattgc cacacataca gagattcaga
    11761 gcctacaact tctatcctta caatcacatc aaatgttgtt tacggtaagg ctacaggttc
    11821 acttcctgac ggcagaaaag caggcgagcc gctttcaccg ggtgctaacc caagctacgg
    11881 tgcagagcag aacggtcttc ttgcttcact taactctgtt gctaagcttc cttacgagta
    11941 cgctcttgac ggtatttcaa atactcagac aatcaacccg ggtgctctcg gacacaacga
    12001 cgacgagcgt gttgacaacc tcgtaaatgt tatggacggc tactttgatc agggcgcaca
    12061 ccacctcaat gtaaatgtat tcggtacaga aaaactcatt gacgctatgg agcatcctga
    12121 gaaggaagag tatgctaact tcacaatccg tgtatcgggt tatgctgtta agttcatcga
    12181 ccttacaaga gagcagcagc tggatgttat tgccagaacc tgccacgaca gaatgtaatg
    12241 tcggacaacg ctgttaaagg ctttgtacac tcaatagaaa cttttggctc tgttgacggt
    12301 ccaggcgtga gatttgtgat ttttctgagc ggttgcgcaa tgcgttgcca gttctgccac
    12361 aatcccgaca cctggaaaca cgatgaaaac accgtggaat acaccgccga cgagttgctt
    12421 aataaagcgc ttgcataccg cccctattgg aaaaataagg gcggtatcac agtaagcgga
    12481 ggtgagccgc ttttacagat tgactttttg cttgatttgt tcaagaaggc taaaaagcaa
    12541 ggcgttaata cctgtattga cacaagcgcc aacccgttta caaccaaaga gccgttctat
    12601 tcaaagtgga aagagctaat ggaatatacg gatttgctgt tgcttgatat aaagcatatc
    12661 gacaacgaac agcacaaaat ccttacagga cagccaaaca ccaatattct tgaaatggca
    12721 agacagcttt ccgatatggg caagcccgta tggataagac atgttcttgt gcctgaaaga
    12781 aatgataagg acgagtatct tttcagactt gccgacttta tccgttcgct caagaatgtt
    12841 gagcgtgtag aggtgcttcc gtatcacacc ctcggtgtgt acaagtggaa ggctctcggt
    12901 tatgactatc ctctcgaggg cattaatccc ccgacaaaag agcgtgttaa gaatgcggaa
    12961 atgattctta acggcgaaaa aacaagagat taatttctta tataaaaacg gcagtaccga
    13021 tttttttggt actgccgttt ttgttttgat ttttatttgt tattctgctt ttgttgtttc
    13081 ttcttcagca aaattgatga atcaaaggtg tattcaaaga tttttaagcc gtccttgttg
    13141 agaaatcgtc acagtcggaa gaaccgactg ctccgacggg tgagcctgca actgtcggta
    13201 caacctctgc aaatccgact tcggcaacag gcggtgccgc aacatcggac agcactcctt
    13261 cacagcctga taaaaacggc agtgttcaga caggagtgac agcaacggct gttatgatgc
    13321 ttgttgtaat ttcgggcgga gtgctttttg cccttgcaga gcgtaaaaag agaatataac
    13381 acactgacag ccatttgtgc aaagattatc agttgtctat tgaaaaattt gtaaaaatga
    13441 tataaaatag caataagtag aaaaatacgg tttttccgct gatttatgat ttatattaat
    13501 actgaaagag gtgccggaat ggataaaaac aaaaaattat tctacacaat catcggtgca
    13561 atctctgcac ttgcggctgc cacagcagca tttctcgctt taaaaaagca cagatgcgca
    13621 gaacagaagc ttattgagga aattgacgat attgtttccg aaaaagagcc tgaggaggct
    13681 gcaaaggaag aaccgcaggc agaagttaca gccgatgagc ttgctgagga agaataagca
    13741 acaagttgtt gcaccaaatt cgggtagcag tatttgtatg tgcgaaagtt aaatacccga
    13801 gcggtgcttt caattaagaa ttgaaagtta aaacagataa tgatgtcggc ggtgtgccac
    13861 cacaatctat tcaagaaaac agtttaaaaa agaaaatgca tcagatgtcc gaaaaggtct
    13921 gatgcatttt tgttttgtta ggctgttttg tcacagcccc atcgaaattg ctcttgacgc
    13981 agactttttt gttacaaaac aattgttgta aaaattaaat acgatagtat tattatcagt
    14041 tatttctgaa ctgtggaata tggattagac aatatccaca ataatctgac aatgaatttg
    14101 tatataatag caaacttacc gttaatttgc acatatttta gggcaaaaaa ttttcgctaa
    14161 aagaataaca gattcattgc ccgaacaact taaatgtgct ataatttaaa tgtcctcgga
    14221 aattttgtac tgttaaagtt tccgaagctt agaagtattg ccacaaaact gtggcgaacg
    14281 gtaattttat tttattaaag gagcagcaag tatgaaaaaa attcagaaaa agctttctgt
    14341 ggttcttgcg gtaatgatgg tgctgtgcat gttcacagct ctgcctttct cagcaagtgc
    14401 tgccgaaaca agcgaagaaa caagtgcagg caacaagatc aatgttacat caaatgtgac
    14461 agatcctgtt tcgtatgatt acaatgcaca gacagagcag gttgttgtta cttaccttct
    14521 caaggcagac cacatgatcg ttgatacaca gagcagcctt acatacgaca gcaaggttct
    14581 caagcttgca tcaacaacaa caacaaatac aaagaaaaag gttttccctg tattccagag
    14641 cagcatcgtt tggaatacaa gcattacaaa tcaggtttac ttcaactgct caagccttga
    14701 tcttttcaac ttcaagtcag agaatgttta ttgcacattt acatttgatg ttgtaggcag
    14761 cggtgacaca acagtaaatc ttaatgttga ttatcttaca ggtacagagg ctgaatcata
    14821 tgatgatttc ttcgaaagtg aaaagaagga catcgattat atttacgata gtgctaacaa
    14881 agtagaaggt gctgcattta ctgcaaaggc agttctcgtt cagggcgaag agccaacaac
    14941 agctcctcag cctacaactg taacacagcc aacaacagca acacagccaa caacagctcc
    15001 cgcaacaaag cctactcagc ctgcaacaga gccgacaaca acaccttcag gtgacggtgc
    15061 aacaatcaag tttgcggctc ctacaagcca ggcatcaaga tacaactgga gcaagcctgt
    15121 actcttctac ggcaacacac agtcagttga caagtcaaca aagctttcaa tgacagcaac
    15181 aagcgagaag tattacacaa cagaagttgg ttcaaacaca cttctcacaa caaacggctg
    15241 gacagtatac gaactcaaga tttcaaagga tcaggcagca gcaatcaatt catcaaagtt
    15301 tgtcggtttt gcaacagcta acggcgtaaa cagaacaact ctcgtaagcg gttcaaatgt
    15361 tcttaaagca ggtgtagata cttacacagc taagtacggt acaacagcaa acacagttgc
    15421 agctcttgac ggcaagacat tcgttatcag agattcagct tacggtgcaa catcatcagt
    15481 atcattcgta ggctattggg taagcgactt tgtaacagta agagcagcag ctccgcttgc
    15541 agcaacatca tattctacat gggacaatgt tgatctttat tatggtaaca caacagcttt
    15601 cgattcaatg acaaagcttt caatgatcaa cacaggcgac acaacaaagg tatcatctct
    15661 caacggcaat atgacaatca aaacaggcag atggtacatc tatgcaatca cacttgataa
    15721 ggcaacagca tcagcagtag aaaatgcaaa gtatgtcggc tttaacaaga cagatgcagt
    15781 aaacagaaca gcaatcctca agaatgtact tttcgcaaag acaaatacat ttgacggcaa
    15841 ctacaactca aaggcaagaa cactttcaga acttgacggt cagctcttcg taatcaaggg
    15901 tatgacagct aaatcatcat cagtagctac atatacaggt gaatgggaaa caaaggatgt
    15961 ttatacacag ggcaaagatg acacagtaac actttacttt gcagcaccaa agggtgtaaa
    16021 gaactatgca aactgggata caggtgtaca gctctattat agcaatgaca atgtttacac
    16081 aaaagctgag agaattgata tgaagaaggt aaacgaaacc aagaaggtaa cagttgattc
    16141 ttcaaaactc aagacactta agtcaggtaa ctgggatgtt tacagcgtaa cacttacagt
    16201 tgaccagatt aaggcaattg ataactgcca gagcgtaggc tttgtaaaga agggttcatt
    16261 caacagaaca gcttacacag catacagaaa tatctgtaag gcaagcaaga tggacggcaa
    16321 ttcaacatac agcggtgttc gtgaatcaat cgaaacattt gacggctata tgttcgtaat
    16381 caactcttgc tacacaccaa gcaatgaaaa catttcactt acaggtagct gggtagtaaa
    16441 gtaatccgat tacttaaaac aaaataaact tattttctcc ccgtacagtt ttgtgcgggg
    16501 agtttttatg tgtgtaatta agttgttcaa agtatttggg ctctatgtca atagttgggg
    16561 tagcattaaa acagaataat tgaaattgac aagtggtggt tgtttaaact gccgcttgtt
    16621 ttgtattgtt ttttgctgat ttgagtgaga acatatgtag aatgcggttg cggaagcg
//
