LOCUS       gnlProkkaCJENKGDL_200  15511 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CJENKGDL_200.
ACCESSION   gnlProkkaCJENKGDL_200
VERSION     gnlProkkaCJENKGDL_200
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 22:38:37
            Original ID  :: gnl|Prokka|CJENKGDL_200
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15511
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15511
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4777:5511]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4778..5511
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..15511
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15511
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             275..505
                     /locus_tag="ctg200_1"
                     /transl_table=11
                     /translation="MDNSVESPASIMKTLSDERRFTDIFIAIPENNAIKTVQHFPVFRA
                     LQECISCIVFWDYKRKIGWGVKKQIWIISQL"
     CDS             484..1137
                     /locus_tag="ctg200_2"
                     /transl_table=11
                     /translation="MDYQSIVTFVMEMAGSVAFAASGAMVGVERNMDIFGVSVLGVATA
                     VGGGMIRDIVLGIIPPAVFTNPVYALVSVLASCIVFFIFYFKRELLQGHRRETYDKIML
                     AMDSVGLGIFTVVGVNTGIRQGYMDNVFLLVFLGTITGVGGGLLRDMMASVPPYIFVKH
                     IYACASIIGAVVCVYMNRFVGNVQAMVVSSIVVVLIRYLAAHYRWNLPRLSPHE"
     CDS             complement(1046..1582)
                     /locus_tag="ctg200_3"
                     /transl_table=11
                     /translation="MNLKGAVVMRKKLNITEGIFPMPVLMVATYNEDGSINVMNAAWGT
                     MQERDTVALNLTETHKTVQNIKARGAFTVSIADAAHVTEADYFGVESGNREPDKFARSR
                     LTATKSETVDAPIINNFPPRTKRQSDKLSLTALNITCLILYGILPIHVVTAWADSSGNV
                     LPDIGSAPLQLMILP"
     CDS             complement(2049..3347)
                     /locus_tag="ctg200_4"
                     /transl_table=11
                     /translation="MEYIILLIFSFFTEAVILWQYAASLFSPSHSGKKRLTLLSVLYVL
                     LFFLSLLGQTWLNIISFFVINTVFLYIMFNLKLLLALFHSAILTAIMGISELAVLGMIS
                     RFFPHFLLEASVGLVFYTVFSKITFFAVVYLLSWLFKGNKAAQEPYGHSEILLMFIPLS
                     SILMMFTLLSIGETTAYAPPVDFLVTICAVFLLLVNLLVFGINQYNTKRSQEYADLQLL
                     LQKESDSVEYYEMMLAQNENQSILIHDIKKHLQSIRLLNEKNDSDKINDYIQQLMESSD
                     LKETTKLCDHEMLNSILCRYQRHCNDKHIIFHTDIRSGTVQHIYPRDLTSLFCNLLENA
                     VESAENIPDSFIELTVQKKENSPFLIIILINSCQNTPVYNPEGLPISHKSDNGRHGFGI
                     KSIKKVVKQYHGNLQMYYDNDSGTFHTILTLKQ"
     CDS             complement(3354..4061)
                     /locus_tag="ctg200_5"
                     /transl_table=11
                     /translation="MRILICDDDTLIIEQLKKYIESYFESNHLKCPELVSFTSGEALLT
                     DKGEKDIVFLDIEMPGMNGIYVGNELKKANRNVIVFVVTSYSEYLDEAMRFHVFRYLSK
                     PLDKQRFFRNLKDALAYYNSITLKIPVETKQAVYSFPASQIIAIEAQGRKVIVHTARQD
                     FDSIHNMNYWLEKLPQNSFFQTHRSFIVNFEHIVDFDHSTVHLSNPQITAYLTRRKYSS
                     FRNAYLLYLESMR"
     CDS             complement(4153..4482)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 57.2; E-value: 4.5e-17)"
                     /gene_kind="other"
                     /locus_tag="ctg200_6"
                     /transl_table=11
                     /translation="MGNRIKIRRKELRIKQAELAERLNISNSHMSSIENGRQKPSLDIF
                     IQICNLLNVTPDYLLLGSMHAYNIPQDIIDKLRLCNQSDIELAGDFIELLVKRNNKATH
                     NEPKL"
     CDS             4778..4927
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg200_7"
                     /sec_met_domain="TIGR04223 (E-value: 1.1e-14, bitscore:
                     44.5, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKEVTKSVAKGMKAALDVVLRTEANTASCLIMYQPKAPKELMNY
                     RRNK"
     CDS             4927..5511
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg200_8"
                     /sec_met_domain="AgrB (E-value: 1.3e-36, bitscore: 115.9,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKCTDTVVNWMIRCNAINEADKELYKYALYSFFLLVSPLILAGV
                     IGFGLGSVKHGVALIFPFVVLRKFSGGYHAKNLHTCILGSGFLLFLCIMLSMHVQCDLK
                     LAIATVIASVSLITFSPIDSENRRLDTNEKRTYKKTTVFFVILFGLLDIALFLLGKYIY
                     TICFSVGILLTAGLQVPCIVKKMCKSTKNRL"
     CDS             5512..5622
                     /locus_tag="ctg200_9"
                     /transl_table=11
                     /translation="MSFGAKGVEIMAKIKIIKFVIDLIKVLYLQLIQFVH"
     CDS             5726..6109
                     /locus_tag="ctg200_10"
                     /transl_table=11
                     /translation="MTHKKEVVFSLLFVIMVLCTGCSDKDNGDTSKNNRTSGESFVQEE
                     TIESTDNTDNADGSSAPTPELKTPRTKKELEDALGTVNESGKWTPPAGSHIDPKTGNIL
                     NKDGVVVGTTQEPYSKARPGSQG"
     CDS             6675..6881
                     /locus_tag="ctg200_11"
                     /transl_table=11
                     /translation="MIKIETKVLFQERVMVMALAQATKSHEPTYTINDAMDVLLSRLDE
                     AIDDMESDRVQIVEEAWAEIDAI"
     CDS             6891..7037
                     /locus_tag="ctg200_12"
                     /transl_table=11
                     /translation="MEKRKYKVVIAQSGKLDVKEKRNISFSNLNTGSMQRIFPKRLKSG
                     SCT"
     CDS             complement(7220..8539)
                     /locus_tag="ctg200_13"
                     /transl_table=11
                     /translation="MISLVVYPVSGHWIWGGGFISQMGFHDFAGSCAVHMVGGVAALIG
                     AIILGPRIGKYTKDGKSKAIPGHNLTVGALGVFILWFCWFGFNGASTVSMEGDAIVSAG
                     KIFVTTNLSAAVATVTVMIITWVRYKKPDVSMSLNGSLAGLVAITAGCDTVSPTSAAII
                     GIASGFIVVFGIEFIDKVLKIDDPVGAVGVHGLNGAFGTLAVGLFSDGSGTDWKGLLTG
                     GGFHGFGVQFTGMIITIAWVVVTMTIIFQVIKHTIGLRVSAEEEIAGLDSKEHGLASAY
                     DGFAMAGVPTPMGTSIKAPVVTARPSAPAESVPELPKEGVHKLTKVVIITRQNKLDEFM
                     QAMNEIGVTGITITNVLGCGVQKGAPSYYRGVEMEMNLLPKVKIEIVVSLVPVQKVIET
                     AKAVLHTGQIGDGKVFVYDIENVVKIRTGEEGYLALQDTK"
     CDS             complement(9231..11330)
                     /locus_tag="ctg200_14"
                     /transl_table=11
                     /translation="MAQNIPELYGSLVFNDKVMRSKLPKDMYKALKKTIESGTHLELDV
                     ANSVAVAMKEWATENGATHYTHWFQPMTNVTAEKHDSFISPTGDGQVIMDFSGKELVKG
                     EPDASSFPSGGLRATFEARGYTAWDPTSPAFIKDGTLYIPTAFCSYSGEALDKKTPLLR
                     SMQTLDKEATKLLHIIGNKDVKHVNTTVGPEQEYFLVDKELYKQRKDLVFCGRTLIGAP
                     APKGQEMEDHYFGALKPRVAAYMHDLDVELWKLGIPAKTKHNEVAPAQHELAPVFDTTN
                     VAVDHNQLTMEVMKKVADKHGLVCLLHEKPFEGINGSGKHNNWSMITDTGINILDPGKT
                     PAENTQFLIFLTAVIKAVDEYADVLRISVASAGNDHRLGANEAPPAVVSVFLGDELTEV
                     LKSIENDEYFAGSRAVQMDIGAKVLPHFVKDNTDRNRTSPFAFTGNKFEFRMLGSEASV
                     ANPNIILNTAVAECVHQFAEQLKDVPEDKMEDAIHELIKKTIIDHKCVIFNGNGYTDEW
                     IEEAEKRGLFNLKSTPDALPQWIADKNIELFTKYHIFTKEEIESRYEIWLESYSKILNI
                     ESNTMVEMVQKDFLPSVFAYIDKVAATAVAKKSVVSDVSTASEGKLIKELSQLADEIST
                     GLETLKADTAKALATEDPLANAKAYQTVVLSDMDELRKSVDAAETLIPDALLPYPTYDK
                     LLFSV"
     CDS             11651..13168
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg200_15"
                     /sec_met_domain="GATase_7 (E-value: 1.6e-23, bitscore:
                     73.3, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILEPVKHKKTMSAGFESKVKVRQENTIGGNQMAGIKEECGVFGI
                     YDLDGGNVVPSIYYGLTSLQHRGQESCGLAVSDTKGERGNVKFHKDLGLVSEVLRQDVV
                     RKYEGDIGIGHVRYSTTGASVAENAQPLVLSYVKGTLALAHNGNLVNTPELKWELIQNG
                     AIFHTTTDSEVIAFHIARERVHSKTVEEAVLKTAKKIKGAYGLVVMSPRKLIAVRDPYG
                     LKPLCLGKRGNAYVIASESCALTSVSAEFIRDIEPGEILTITKDGLKSNKELASAAAKR
                     AHCVFEYIYFARLDSTIDGVKVYDARIRGGKSLAKSYPVEADLVTGVPESGLPAAKGYS
                     EASGIPFAFAFYKNSYIGRTFIKPTQEERESSVHLKLSVLESVVKDKRIVLVDDSIVRG
                     TTIANLIHMLKEAGAKEVHVRISSPPFLHPCYFGTDVPSNDQLIAASHSTEEICKMIGA
                     DSLGYMQTDYLEGMAGGLPLCKACFDGNYPMEIPDYTNAEFADIVKC"
     CDS             13339..13665
                     /locus_tag="ctg200_16"
                     /transl_table=11
                     /translation="MDKFKNLTNSEMWNIIWASDRKKQRMFSERVITMSQSKIKLNATE
                     EVQEFVNAASRCDFDIDVYYNRFLIDAKSILGVLSLDLTRELTVDCHGESREFDRTLKK
                     FAVA"
ORIGIN
        1 ctgaaaacac cggaaataat aaaagtagct gtatagctct aaagagcaaa cagtagtggt
       61 gtcatggatg caccctgaaa aaaaggcggt atcccgcctt aattcagatg ctctggtaac
      121 tcagttgccg agtaattcac ttactatact atgctgaagg tgttcgcgaa gtatataagt
      181 ttatctatat gaaatggaat aaatagtcga ttttctgata ctgattgaga gtaaagactc
      241 tttcacgtga cgttcaaaaa atcgactttt tatcttggat aattcagtgg aatctcctgc
      301 ttcaattatg aaaacattaa gtgatgaacg gagatttact gatattttta tagcaattcc
      361 agaaaataat gcaattaaga cagttcagca ttttcctgtc tttcgtgctt tgcaggagtg
      421 cattagttgc attgttttct gggattataa aagaaagata ggatggggag ttaaaaaaca
      481 aatatggatt atcagtcaat tgtaacattt gttatggaaa tggccggttc agtggcgttt
      541 gctgcttccg gagcgatggt gggcgttgaa cggaatatgg atattttcgg cgtgagcgtt
      601 ctgggagttg caacagcagt aggcggagga atgatcaggg atattgttct ggggatcatc
      661 cctccggctg tatttaccaa tcctgtatat gcactggtgt cagtgcttgc ttcctgcatt
      721 gttttcttta ttttttattt caagagagaa ttgcttcagg ggcacaggcg tgagacctac
      781 gataaaatca tgctggcaat ggactctgtc gggcttggga tttttacagt agtaggagta
      841 aatacaggaa tccgccaggg atatatggac aatgtgttcc tgcttgtatt tcttggaacc
      901 attacgggag taggcggcgg tctgcttaga gatatgatgg cgagtgtacc gccgtatatt
      961 tttgtaaaac atatctatgc ctgtgcctcc atcattggtg cagttgtatg cgtatatatg
     1021 aatcgatttg tgggaaatgt acaggctatg gtagtatcat caattgtagt ggtgctgatc
     1081 cgatatctgg cagcacatta ccgctggaat ctgcccaggc tgtcaccaca tgaataggaa
     1141 ggataccgta taaaatcaga caggtaatat ttagcgcagt caggctgagt ttgtctgact
     1201 gtctttttgt tcgaggagga aaattattga taatcggagc atctacagtt tcagattttg
     1261 tggcggtcag acggctgcgg gcaaatttat caggctcgcg attaccggat tctacaccga
     1321 aatagtcagc ttctgttaca tgtgcggcat ccgcgatgct gacggtaaat gcaccgcgtg
     1381 ctttgatatt ctgtacggtt ttatgggtct cggtaaggtt caatgcaact gtgtcacgtt
     1441 cctgcatcgt accccaggca gcgttcatta cattgatgct tccgtcttca ttataggttg
     1501 caaccatcaa tacaggcata ggaaaaatgc cttctgtaat atttaatttt tttctcatta
     1561 caacagcccc tttcagattc aattgacagg ataatatatc ctgctataaa tgagcaagtt
     1621 tgaaaaaatg cacaaaatta tcctgctaat ttcataaatg cttcaaaatc atcacttgct
     1681 tttgcacata ggaatagata ctgatacttt tcctgatgaa cggcactaca gattcgatga
     1741 tatccatctt gaaaagatcg atatttgcca gttcctgtga cacaaataca atgtgccagt
     1801 gacatcagca gccagtatct ctgtatttcc tttgagaaac ggatctggta tgtatccagt
     1861 gccagacggt ttttacattg cctgaaaaat atctcgatcg gccatcgaca cacataacag
     1921 gaaaagatct ctttctttta tgcaaaatca cgaacttgct catttatagt gatataaaac
     1981 aacatcaatg catgctgaaa tatgtaaaaa ggcaatcgta taaaattgcg attgccagat
     2041 tttaatattt actgctttaa ggttaggatt gtatggaagg taccggaatc attatcataa
     2101 tacatttgca aatttccatg gtactgtttt acgacttttt taatgctttt gattccgaat
     2161 ccatgtctgc cattgtctga tttatgggat ataggaagtc cctctggatt atatacaggg
     2221 gtattttggc aggagttgat gagtatgata ataagaaagg gtgaattttc tttcttttgt
     2281 acggtgagct caataaaaga gtctggaata ttctctgctg attccactgc attctccaat
     2341 aagttacaga ataaagaagt caaatcgcgc ggatatatat gttgtaccgt gccgcttctg
     2401 atgtcagtgt gaaaaataat gtgcttatca ttgcagtggc gctgatagcg gcacagaatg
     2461 gagtttagca tttcatgatc acagagtttt gtggtttcct ttaagtcgga agattccatg
     2521 agttgttgta tatagtcatt tattttatcg gaatcatttt tttcgttcag taatctgatt
     2581 gattgaagat gtttctttat atcgtggatc aaaatgctct ggttctcgtt ttgtgcaagc
     2641 atcatttcat agtattcaac agaatcggat tctttctgga gcagtaactg caaatcggca
     2701 tattcctgtg atctttttgt gttatattgg ttgattccaa atacaagtag gttgaccagc
     2761 aacagaaaaa cggcacagat tgttactaga aaatcaaccg gtggggcata tgcggttgtt
     2821 tcaccaatag aaagaagagt aaacatcata agaatagagg aaagcgggat gaacatcaag
     2881 agaatttcgg agtgaccgta cggttcttga gctgctttgt tccccttgaa gagccaactt
     2941 aacaagtaaa cgactgcaaa aaaggtaatt ttgctaaata cggtataaaa aacaagtccg
     3001 acacttgctt ctaagagaaa atggggaaag aatcttgata tcatccccaa aactgcaagt
     3061 tcagatattc ccataatcgc tgtaagtata gcggaatgga agagtgccaa taataacttg
     3121 aggttaaaca ttatatagag gaaaacagtg tttatcacaa aaaaactgat aatattcagc
     3181 catgtttgcc caagcaggga aagaaaaaac aacagtacat aaagaacact taatagagtc
     3241 agtctctttt taccgctatg agaaggggaa aaaaggctgg cggcgtactg ccataagata
     3301 accgcttctg taaaaaaact aaaaataagt aaaataatat attccattta ttttcacctc
     3361 atgctttcca gatatagtag atatgcattt ctgaaggaac tgtatttcct gcgtgtcagg
     3421 taagcggtaa tctgaggatt tgataaatgt acggtggagt gatcaaagtc cacaatatgt
     3481 tcgaagttaa caataaagct ccggtgtgtc tgaaaaaaac tgttttgggg aagcttttcc
     3541 aaccagtaat tcatattatg aatagagtca aagtcctgac gggcagtatg tacaattact
     3601 tttcgcccct gagcttctat ggcaataatc tgcgaagcag gaaacgaata taccgcctgt
     3661 tttgtttcca caggaatttt gagtgtaatg gaattgtaat aagctaaggc atccttcaga
     3721 tttcggaaaa aacgctgctt atctagaggt ttggaaaggt aacggaatac atgaaaacgc
     3781 attgcttcat ccaaatattc agaataagag gtgacaacaa aaacgatcac atttctattt
     3841 gcttttttta attcattccc aacatagatt ccattcatgc caggcatttc gatatccaga
     3901 aaaacaatat ccttttcacc tttgtcagtt aacaaagctt caccactggt aaaagaaact
     3961 aattcaggac attttaaatg gttggactca aagtaggatt cgatatactt cttcaattgt
     4021 tcaatgatca gagtgtcatc atcacaaatt aaaatacgca ttttttcacc tgactttcta
     4081 aatagatgta tgtgtacatc ttatcacata gaatttccaa atgcaaaaaa tgcgtatgaa
     4141 aagacaattt aattacaatt ttggttcatt atgtgttgct ttgttatttc gttttacaag
     4201 cagttcgata aagtctccgg caagctctat gtcggattga ttacataacc gtagtttatc
     4261 aataatatcc tgtggaatat tataagcgtg catactgccg agcagaaggt agtcaggtgt
     4321 aacattgagt aaattacaaa tctgaatgaa aatatccaga cttggttttt gccttccgtt
     4381 ttcgattgat gacatatggc tattggatat atttaatctt tcggcaagtt ctgcctgttt
     4441 tatccgtaat tcttttctgc gtattttgat gcggtttccc ataccttcat attgaaattc
     4501 tatttatccc accttctttc agtagaattt taccaataga actaaataaa aagaagaatg
     4561 taacaaagaa ctattctgca atatattaaa caaactgata tttatatata aataattctg
     4621 tatcacatat tatttttcgt agaaaagagg gaaattatcc aatattgtaa agaatcattc
     4681 cgttcattcc aaaggggtcg tttatttgat taaagtggta tatgattgct tatgtgaaaa
     4741 tcaatgacaa attttagtgg aaaggagaga ggtcattatg aagaaagagg taactaaatc
     4801 ggttgcaaaa ggaatgaaag cagcattaga tgttgtgtta cggacagaag ctaacacagc
     4861 ttcttgtctt atcatgtatc agcctaaggc accgaaagaa ttaatgaact acaggagaaa
     4921 caagtaatgg aaaaatgtac agatacagta gtaaattgga tgatccggtg taatgcgata
     4981 aacgaggcgg ataaggaact ttacaagtat gcattatata gtttttttct attggtatca
     5041 ccacttatcc ttgcaggagt tattggcttt ggcttgggaa gcgtaaaaca cggagttgct
     5101 cttatttttc cgtttgtggt tctgagaaaa tttagtggtg gttatcatgc aaaaaatttg
     5161 cacacttgta ttcttggatc tggttttcta ttgtttctgt gcataatgtt atcaatgcat
     5221 gtgcaatgtg atttgaagtt ggcaatagct acagttattg cgtctgtgag cctgattaca
     5281 tttagtccaa tagacagtga aaacagaaga cttgatacta acgagaaaag gacatataaa
     5341 aaaacaacag tgttcttcgt gatactgttt gggctgttag atatagcttt atttttgctg
     5401 ggaaagtaca tctatacaat ctgtttttct gttgggatat tactgacagc aggcttacaa
     5461 gtaccttgta tcgtaaagaa aatgtgtaaa tcgaccaaaa acagactgta aatgtcgttt
     5521 ggtgcaaaag gggttgaaat catggcaaaa ataaagataa taaagtttgt cattgatttg
     5581 atcaaagttc tttatttaca gttaattcag tttgttcatt gaaagggagt ggattccaat
     5641 gggacaatga tagaattcta tcactttaaa ttgagtagtt cggttcggag tagttaaacg
     5701 ggcataatgg aggtaaaaga ttaaaatgac acataagaaa gaagttgttt ttagcttgtt
     5761 gtttgtaata atggtgttat gtacaggctg cagtgataaa gataatggag atacgtctaa
     5821 aaataacagg acttcaggag aatcatttgt tcaagaagaa actattgaga gtactgacaa
     5881 tacagacaat gcagacggca gctcggcacc aacgccagaa ctgaaaacgc cccgaacgaa
     5941 aaaggaattg gaagatgcgc ttggtacagt gaatgagtcg ggaaaatgga cgccaccagc
     6001 cggttctcat atagatccca aaacaggtaa tatactgaat aaagatgggg tcgtggttgg
     6061 aactacgcag gaaccttata gtaaagcacg tccaggttct caaggatgat gatatggtgt
     6121 aaaaaaatta tgggaggaaa agattatgaa gtatatgaga aaaaactcat ttgtagtgtg
     6181 tttggtcata agtgcaattc ttttgacaag ttcatttgca atgccggtgc ttgctgcgga
     6241 aaatacagga attgaaacaa gctctgtcac gagaagcgta ccgggatatt acaagtgcac
     6301 agggtcggat gtaaatatca gatcaggccc tggaacacaa tatacaatag taggcacatt
     6361 gaattatggc acaaaagtat atgtatattc tatcagtaat gggtgggcca aaatttctct
     6421 tggcggcatt taccgttatg ttagtgccga ttaccttcgg gagctttaag gaaaaacatt
     6481 taatataaac gaggcatagg taaatagctg tatgggctgc cgcactgaaa agtttggtgc
     6541 ggcagcactt ttgtttactt ttttaattga aactacaaat ggacaaattc taaaaaacgt
     6601 cccaaaaaca gtattctgtg tttgggttat aaagacaaat ttaaaatata tagatatttc
     6661 cggtggttcg tggtatgata aaaatagaaa caaaagtgct atttcaagaa agggtgatgg
     6721 ttatggcatt ggcacaggca acaaaatccc atgaaccaac ttatacaatc aatgatgcaa
     6781 tggatgttct tttgtcaagg ctggatgaag ccattgatga tatggaaagt gacagagtgc
     6841 agatagtgga agaagcatgg gcagaaattg atgcaatata aggggtacgg atggaaaaaa
     6901 gaaaatacaa agttgtaatt gcccagagcg gcaagctgga tgtgaaggaa aaaagaaata
     6961 tatccttcag caatttaaat accgggagta tgcagaggat ttttcccaaa agattaaaaa
     7021 gcggttcttg cacttgacac acttcctacc agatataata caataggctt ccgatatcgt
     7081 ggctatgata tttacatgaa atatactgcc tgttttttaa cgccattgga attgttagaa
     7141 agaaagatta aaataagaga caccagcaat caatacgctg atgtctctta ttaatattac
     7201 ctgattgttg ataaataatt tactttgtat cctgcagtgc gagataacct tcttcgcctg
     7261 tacggatctt aacgacattt tcaatgtcat atacaaatac tttaccatca ccaatctgac
     7321 cggtatggag gactgccttg gcagtttcga taactttctg tacaggtacg agacttacaa
     7381 caatctcaat tttgacctta ggaagaagat tcatttccat ctcaacacca cgatagtagg
     7441 atggagcacc tttctgtaca ccgcatccga gaacgttcgt aatagtgata cctgtaacac
     7501 cgatctcatt cattgcctgc ataaattcat caagcttatt ctgacgggtg atgataacaa
     7561 cttttgtaag cttatgaacg ccttctttcg gaagttcagg aactgattca gcaggagcag
     7621 aaggtctggc tgtgacaaca ggagctttta tggaagttcc cataggagtc ggaacgccag
     7681 ccattgcgaa accgtcataa gcacttgcaa gaccatgttc tttggagtca agacctgcga
     7741 tctcttcttc agctgaaaca cgaagtccga ttgtatgttt gattacctgg aagataattg
     7801 tcatagtaac aacaacccat gcgattgtga tgatcatacc agtgaactga acaccaaatc
     7861 cgtggaagcc gccgcctgta aggagtcctt tccagtctgt gcctgatccg tctgagaaaa
     7921 gaccaactgc aagggtaccg aaagcaccgt ttaaaccatg aacaccgaca gcaccaacag
     7981 ggtcatcaat tttcagaacc ttgtcaataa attcaatacc aaatactacg ataaaaccgg
     8041 aagcaatacc gatgattgct gcggatgtag gagaaactgt gtcgcatcct gctgtaattg
     8101 ctacaagtcc tgcaagagaa ccgttcagag acatggaaac atccggtttt ttgtaacgta
     8161 cccatgtgat gatcataaca gttacagttg caacagctgc tgaaaggtta gtagtaacga
     8221 agattttacc ggcacttacg attgcatcgc cttccatact tactgtggaa gcaccgttaa
     8281 atccgaacca gcagaaccag aggataaata cacctaaagc gccaactgta aggttgtgtc
     8341 ccgggatagc ctttgatttg ccgtcctttg tatatttacc gatacgaggt ccaaggatga
     8401 tggcaccgat cagagctgcc acaccaccta ccatatgtac tgcacaggaa cctgcgaaat
     8461 cgtggaatcc catctggctg ataaatccac cgccccagat ccagtgtccg gataccggat
     8521 atacaacaag actgatcata aggctgtaga tgcaatagga aaggaacttg gtacgttctg
     8581 ccattgcacc ggaaacaatt gttgcggatg ttgcacagaa tactgtctgg aagattaaga
     8641 atgcccagaa aggaactccg tcaggaagca ttcctgaacc atagtgtgct tctgtggcaa
     8701 taccaccgat ctttccgata aatccattac ctgcaccaaa catcagaccg aagccgacca
     8761 gccagaagac cggggttccg atacagaagt ccatcaggtt tttcataata atgttacctg
     8821 cgtttttggc tcgtgtgaag cctgtttcta ccattgcgaa tccggcctgc ataaagaaga
     8881 ccagtgcggc gccgaccagc acccatattg tgtttactgc ggaaaattcc ataataatat
     8941 tcctccctca taaaaatttc ctcatatttt ataaaatgca aaaagcgcga tgcctggaaa
     9001 tgtagccagt tcatcgcgct tttgcgaata taaaatccat atttatagtg tattgcataa
     9061 ctgatgtaat agaaaagaca tttcgtatga ctgtatgcaa tgcagtttaa aatcaaaatt
     9121 atatgtaaaa caggggaaca tcaaaatatc gtgtgattaa tggatgagga aatcgataat
     9181 gaattatgaa gtagagttca taaagatatt cccctgttat tacctgttaa ttaaacggaa
     9241 aacagaagct tgtcatatgt aggatatgga agcagtgcat ccgggatcag agtttctgct
     9301 gcgtctacag attttctgag ttcatccata tcagaaagaa caactgtctg gtatgctttt
     9361 gcattagcca gaggatcttc tgtagcaagc gctttggcag tgtctgcttt taaggtctca
     9421 agacctgtgg aaatctcatc agcaagctgt gacagctctt tgatcagttt tccttcagaa
     9481 gctgtgctga catctgaaac aactgatttt ttagcaacag cagtagctgc aactttgtcg
     9541 atatatgcga atacagatgg aaggaaatcc ttctgtacca tttcaaccat agtattggac
     9601 tcaatgttaa gaatcttgga ataggattcc agccagatct cataacggga ttcaatttct
     9661 tcttttgtga agatatgata tttggtaaag agttcaatat ttttatctgc gatccactga
     9721 ggaagagcat ctggtgtaga tttcaggtta aagagacctc gtttctcagc ttcttcgatc
     9781 cattcgtctg tataaccgtt tccgttaaag ataacacatt tatgatcaat aattgtcttc
     9841 ttgatcagtt cgtggattgc atcctccatc ttgtcttccg gtacatcctt taactgttct
     9901 gcaaactggt gaacacactc agcaacagca gtgtttaaaa taatgttcgg gtttgcaaca
     9961 gaagcttcgg aaccaagcat acggaattcg aatttgttac ctgtaaatgc gaatggtgaa
    10021 gtacggtttc tgtctgtatt gtcttttacg aaatgtggaa gtacttttgc accgatatcc
    10081 atctggactg cgcggcttcc tgcaaaatat tcgtcatttt cgatagattt taatacttct
    10141 gtcagttcat caccgagaaa tacggataca acagcaggcg gagcctcgtt tgcaccaaga
    10201 cggtgatcat ttcctgcact tgctacagaa atacgaagta catctgcgta ttcatcaact
    10261 gctttgataa cagctgtcag gaaaatcagg aactgtgtat tttcagcagg tgtttttccc
    10321 ggatcaagga tatttatacc agtatctgtg atcatagacc agttgttgtg tttaccgctt
    10381 ccgttgattc cctcaaatgg tttctcatga aggaggcata caagtccatg cttgtcggca
    10441 actttcttca ttacttccat tgttaactgg ttgtggtcaa ccgcaacgtt tgttgtatcg
    10501 aatacaggag ccagctcgtg ctgtgcagga gcaacttcgt tatgttttgt tttggcagga
    10561 ataccaagtt tccagagctc tacatccagg tcatgcatat aagctgcaac acgaggtttc
    10621 agagcaccga agtaatgatc ttccatttcc tgacccttag gagcaggagc accgatcaat
    10681 gtacgtccgc agaatacaag gtcttttctc tgcttgtata attccttgtc taccaggaaa
    10741 tattcctgtt caggacctac agttgtattt acgtgtttga catctttatt acctattata
    10801 tggagaagtt ttgtagcttc tttatcaagt gtctgcatgg aacgaaggag aggggtcttt
    10861 ttatcaagag cttctccgct gtaggagcag aatgctgtag gaatgtaaag agttccgtct
    10921 ttgatgaatg ccggtgatgt cggatcccat gctgtatatc ctcttgcttc gaatgtggca
    10981 cgaagaccgc ctgacgggaa actggaagca tccggctcac cttttacaag ttctttacct
    11041 gagaaatcca tgatcacctg accatctcct gtaggagaaa tgaaactgtc atgtttctct
    11101 gcagttacgt ttgtcattgg ctggaaccag tgagtataat gagtggcgcc gttctcggta
    11161 gcccattctt tcattgcaac agcaacggag ttggcaacat caagttcaag gtgtgtaccg
    11221 ctctcgattg ttttctttaa tgctttgtac atgtcttttg gcagtttact tctcattact
    11281 ttgtcgttga agaccaggct gccgtacagt tcagggatat tctgtgccat ataggtactc
    11341 tcctttcggt ttgcaatatt ttctgaatat gtgtagtgcc gctgcagatc accattgtga
    11401 ctgcctgcgg ttttcgtctc atagaaaatt cctcatcgaa cattttctat gaaacgaaag
    11461 ttttataaaa cgaaaaaagc gccctggatg agatctctgt agatctttcc aaagcgcctt
    11521 tgctttatgt gctgtactat aaacgaaatg aaaacagatg tcaagcactt tttttgaaaa
    11581 aattcagaaa aaatttttga gatatggcaa aaaaaggata ggttgacaaa tttgtttcta
    11641 ttattataat ttgattttgg aacccgtcaa acataagaaa acaatgtcag cgggttttga
    11701 aagtaaagtt aaagtcagac aagagaatac gatcggagga aatcagatgg ctggaataaa
    11761 agaagagtgc ggcgtctttg gaatttatga tctggatggc ggcaatgtag ttccgtccat
    11821 atattatgga ctgacttccc tgcagcacag aggacaggaa tcctgcggac ttgcagtttc
    11881 tgatactaag ggagagcgtg gaaatgtgaa gtttcataag gatctgggac ttgtaagtga
    11941 ggttctcaga caggatgttg tccgtaaata tgagggagat attggtattg gtcatgtaag
    12001 atattccaca acaggagctt ctgttgcaga gaatgcacag ccccttgttt tgtcttatgt
    12061 aaagggaact cttgcacttg cacataacgg aaatctggtt aatacaccgg aactgaaatg
    12121 ggaactgatc cagaatggag cgattttcca tacaactaca gattcagagg ttattgcgtt
    12181 ccatatcgca agagaacgtg tgcattctaa aacagtagaa gaggcagtgc taaagactgc
    12241 aaagaagatc aaaggtgcat atggtctggt agttatgagc ccgagaaaac tgatcgcagt
    12301 ccgcgaccca tatggactga aaccattgtg tctcggtaaa agaggaaatg cttatgttat
    12361 tgcttctgag agctgtgctc tgacatctgt aagtgcggaa tttatccgtg acattgagcc
    12421 gggtgagatt cttacgatca caaaagacgg actgaagtca aataaagagc ttgcgtctgc
    12481 tgctgcaaaa cgcgcgcatt gtgtgtttga gtatatatat tttgcaagac ttgacagtac
    12541 cattgatggg gtgaaggtct atgatgccag aatccgcggt ggtaaatctc ttgccaagtc
    12601 ttatcctgta gaggcagatc ttgtaacagg tgtaccggag tccggactcc ctgctgcaaa
    12661 gggatactcc gaagcatcag gaatcccgtt tgcatttgcg ttctataaaa acagctatat
    12721 tggaagaaca tttatcaaac cgactcagga agaacgtgag tccagcgttc atctgaaact
    12781 gagtgtgctg gaatctgttg taaaagataa gaggattgtt ctggtggatg attctattgt
    12841 tcgtggaaca accattgcaa acctgatcca catgttaaaa gaggcgggag caaaggaagt
    12901 gcacgtacgt atcagttcac cgccattttt acatccatgc tatttcggaa cggatgtgcc
    12961 gtcaaatgat cagctcattg cagccagcca cagcacagag gaaatctgta aaatgatcgg
    13021 agcagattct cttggctaca tgcagacaga ttatctggaa ggaatggcgg gcggcctgcc
    13081 cttatgtaag gcatgcttcg atggaaatta tccgatggag attccggatt atacaaatgc
    13141 ggagtttgca gatattgtga agtgttaagt cgcaaaaatt cataaaaaat gcagaaacct
    13201 gtcgatgata tatggaatca atctcacata atggtaaaac caatatagaa tggaatcata
    13261 catagtgtat aaaataatgc tgtgaaaaca tatataaacg aacaaaatgc acaatagaac
    13321 ccctgcgctt tatgaaaatt ggataaattt aaaaacttga caaattctga aatgtggaac
    13381 ataatatggg cgtctgatag aaaaaaacaa agaatgtttt cagaaagggt gatcacgatg
    13441 tcacagagta aaatcaagtt aaatgcaact gaagaggtgc aggaatttgt gaatgctgca
    13501 agcagatgtg attttgatat tgatgtttat tacaacagat ttttaattga tgccaaatca
    13561 atccttggtg tacttagtct ggatctgacc agagaactga cagtagactg ccacggggag
    13621 agccgggaat ttgatcgtac attgaagaaa tttgcagttg cataaatttt gcatttttat
    13681 aaccgaataa ttattgcaga gaagacgggt ctggaagatg aacttctaca gattcgtttt
    13741 ttctgtatta tgactgtgtt cagagtaatt ccataaaata taactgcttc atagtttatc
    13801 agaaggaact tatttgattt gtttttgctt aaaaacggga aattcattat tgacaaacga
    13861 aaaaaaatgt tttatagtat agcatatttt taaagaaagc caattgaaca tattattata
    13921 gaagatatga tgatctgaca aaggcgtcag atgcagaata ccagatgggt caagtgccct
    13981 ctgatagctg catctgacgc ttttttatta acaaaggatg atggaggagg aaatcaaaat
    14041 ggcagtgaaa tacgtatttg ttacaggagg agttgtttcc ggtcttggaa agggaatcac
    14101 agctgcatct ctggggcgtc ttctgaaagc gagaggatac caggtaacca tgcagaagtt
    14161 tgatccttat atcaatatcg accccggaac catgaacccg attcagcacg gagaagtttt
    14221 tgtaacagac gatggtacag agacagacct ggatctggga cattatgaga gattcattga
    14281 tgagagtctt gataaaaatt ccaatgtgac aaccggtaag gtttactggt ctgttcttca
    14341 gaaagaacgt cacggggatt tcggcggggg taccgtacag gtaattcctc atattacaaa
    14401 tgagattaag agccgtttct accgcgccaa atcaccggag gaaaacaaga ttgccattat
    14461 cgaggtggga ggaacagtcg gtgatattga aagccaaccg ttcctggaag caattcgtca
    14521 gttccagctc aatgtgggac atgacaatgc aatcctgatc cacgtaacat taattcctta
    14581 tttaaaggca tctgaagaac tgaaaacaaa acctacacag gcaagcgtaa aggaacttca
    14641 gggaatggga atccagccgg atgtactggt gtgcagaagt gaacatgagc tgacagagga
    14701 catcaaagaa aaaatcgctt tattctgcaa cgtacctgta tcacatgtac ttcagaacct
    14761 ggatgtggaa tatttatatg aagctcctct tgcaatggaa agagagaagc ttgcagatgt
    14821 agttctttca agtctccgtc ttgaaaacag aaaaccggat ttaagtgact gggaggaaat
    14881 ggtagaaagt ctgagaaatc cgaataaaac agtaaagatc gcaattgtag gaaaatatac
    14941 acagcttcat gatgcatatc tcagtgtagt agaggcactg aaacatggcg gaatttcctg
    15001 cagagccaag gtagagcttg actggatcga ttccgaagaa ctgacagaga agaatctgga
    15061 tcagcagctt cacaatgtag atggtatcct ggttccgggt ggtttcggga acagaggtac
    15121 agaaggaatg atcctggcag cacagtatgc aagagtacat aagattccat atcttggaat
    15181 ctgtctggga atgcagatgg caattgtaga attcgcccgt catgtacttg gatacgaaga
    15241 tgcaaacagt attgaactga atccggagac aaagcatccg gtaattgcat taatgccgga
    15301 tcaggaagat atcgaagata tcggtggaac cttaagactt ggaagttatc catgtattct
    15361 tgcagaaggt tccagatcct atgaactctt tggcaaaaaa gaaatccatg agcgccacag
    15421 acatcgttat gaagtaaaca atgcattccg taaagaactt caggagaagg gaatgaatat
    15481 cgtaggaact tcccctgata atcatatcgt a
//
