LOCUS       gnlProkkaCJENKGDL_130   7661 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CJENKGDL_130.
ACCESSION   gnlProkkaCJENKGDL_130
VERSION     gnlProkkaCJENKGDL_130
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 22:38:37
            Original ID  :: gnl|Prokka|CJENKGDL_130
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7661
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7661
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1:5632]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..5632
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..7661
                     /SMILES="NC([*])C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7661
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             2..5632
                     /NRPS_PKS="Domain: AMP-binding (1-303). E-value: 6.2e-62.
                     Score: 201.3. Matches aSDomain:
                     nrpspksdomains_ctg130_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (412-473). E-value: 1e-10.
                     Score: 33.9. Matches aSDomain:
                     nrpspksdomains_ctg130_1_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_LCL (485-761). E-value:
                     1.7e-38. Score: 124.2. Matches aSDomain:
                     nrpspksdomains_ctg130_1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (909-1300). E-value:
                     6.6e-95. Score: 309.9. Matches aSDomain:
                     nrpspksdomains_ctg130_1_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1405-1472). E-value: 4e-21. Score:
                     66.9. Matches aSDomain: nrpspksdomains_ctg130_1_PCP.1"
                     /NRPS_PKS="Domain: NAD_binding_4 (1516-1754). E-value:
                     2.9e-35. Score: 113.4. Matches aSDomain:
                     nrpspksdomains_ctg130_1_NAD_binding_4.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     144.5; E-value: 9.3e-44)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg130_1"
                     /sec_met_domain="Condensation (E-value: 1.7e-49, bitscore:
                     156.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.2e-104, bitscore:
                     337.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.6e-12, bitscore:
                     34.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 5.7e-09,
                     bitscore: 23.5, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1e-14, bitscore:
                     42.3, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2.1e-36, bitscore:
                     113.4, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMMEDSSAKLLIADRELLPLVDGYKGPVLFTDQIWQLEDRDVVLK
                     KPQLHDLFILLYTSGSTGVPKGCMLEYGNITAFCHWFKRYYGIDSESRIAAYASFGFDA
                     CMMDIYGAITNGAQLHIIPEEIRLDFIGLQRYFEENGITHSFMTTQVGRQFALEMDCKS
                     LRYLSVGGEKLVPCEPPKDYKFINAYGPTEATIFTTVFEVDKYYPNVPIGKALDNVKLY
                     ITDKLGHMLPPGACGELMITGWQVSRGYLNKPEKTAEVYTKNLYDDTPGYEVMYHSGDV
                     ARFLPDGNIQIIGRKDSQVKIRGFRIELSEVEEVIRRYEGIRDATVVAFDDPNGGKYIA
                     AYVVSDSTVDINALNDFIKETKPAYMVPAVTMQIDKIPLNQNQKVNKKALPLPEKKAAE
                     IIKPENEVQQILFDCIAEVLGYTDFGITTDIYEAGLTSITAIKLNILISKAFDIVIKTS
                     DIKNHPTIRMMEEFVKTAGKESKREVQESYPLTNTQEGIFIECTANMGSTIYNIPYLLK
                     LDNKVDLDRLAEAIDSTVEAHPYLKTRLFMDDNGNVLQKRNDGLSYKTPILNGMNRDTL
                     VRPYMLFNEQLFRFEIYRTCDGNYLFLDLHHIVADGTSLAIIINDINRAYSGEKLEPEG
                     YTSYDLALDNRDALAGDIYKNAENYYKSVFEHAGGSISFYPDKNGAAPTAELYHRETRS
                     ISVQDVKEFCKKHGITENVFFISAFGITLGKYNFKKDAVFTTIYHGRNDSRLSETVGML
                     VKTLPVFCDFSGTAKDCLSGVQKQLIDSMNNDIYPFSQISHEFDIKADAMVIYQGDNFA
                     FDTIGGEYAQEEPVSLNMAKAPVSVSISIEKNRFVFEIEYRGDMYHEETIRYLADNLET
                     TAEGILRECDPADIRLMFEEETQMEDIPEHAGKTFIDLFKEMAARYPDRPAVRDDSGDF
                     TYRELDRMSDYIAQKLTENGFGPEQAAGILCGRTKEYTVAYVGVMKAGGAYVPLDPEYP
                     QSRIEYMLKDSGARNLLVIDQYQNLVEFYDGNVISLDSVSDEAEDFELSAELISPKPEN
                     LAYMIYTSGSTGKPKGVMIEHRNLLNLIEYITLSRNTSPDDIVAEFASFCFDASVIDLF
                     APLTAGAVLYILPESIRKDAIAISRYIKEKEITTVTFPTQMGELVTELLEDAPALKFVT
                     LGGEKFKHYRNRTYQMINGYGPTENTVSSTEFWVDRQYDNIPIGKSQRNVRSYIVDENL
                     NRLPVGASGELCHAGRQIARGYHNLPEKTASVFVENPFAVCEQESRLYRTGDMVRMKGD
                     GNIEYIGRIDSQVKIRGYRVELGEIEGALLKHELVKNAAVTVIEKGGNKYITAYYTGEA
                     IPEDELKTFLEPLIPDYMMPSFFVSIEEMPVTPGGKIDKKALPMPEVTTNTASYVEPVT
                     AAQRALCEIFEKALGIERVGIEDNFFELGGSSLTASKVAVMCLSKNISLVYADIFKYPT
                     VRELAALVDDDGVTEAAQSKNEFSDYNYNRIQNVISANTEENADRITKEKLGDIMVTGA
                     TGFLGIHVLKAFIDNYDGKVYCLVRKGKYESPEKRMMNMLMYYFDDPYKELFESRIICV
                     DGDITSKEQVTGFSEYKFSTIINCAACVKHFAADDVLERINVQGVENLIDFCKNNGRRL
                     IQISTVSVAGEGSDGVPPMSRVFCENDLYIGQNITNEYIRTKFLAERAVLEAVSEGLDG
                     KVVRVGNLMSRNSDGEFQINFITNGFLRSLRGYAAVGKFPMGGMHEVAEFSPIDSTALA
                     VLRLAQTDRRFTVFHACNSHHIYMADLIYAMRSYGFRIDIVRDEEFEAAVKEFAKTGQD
                     SDAVSGLIAYTSHNENEIYTIDYSNRFTAQVLYRLDYKWPVTDDRYLENAIAALDRLTF
                     FD"
     aSDomain        5..910
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg130_1_AMP-binding.1"
                     /evalue="6.20E-62"
                     /label="ctg130_1_AMP-binding.1"
                     /locus_tag="ctg130_1"
                     /protein_end="303"
                     /protein_start="1"
                     /score="201.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="MMEDSSAKLLIADRELLPLVDGYKGPVLFTDQIWQLEDRDVVLKK
                     PQLHDLFILLYTSGSTGVPKGCMLEYGNITAFCHWFKRYYGIDSESRIAAYASFGFDAC
                     MMDIYGAITNGAQLHIIPEEIRLDFIGLQRYFEENGITHSFMTTQVGRQFALEMDCKSL
                     RYLSVGGEKLVPCEPPKDYKFINAYGPTEATIFTTVFEVDKYYPNVPIGKALDNVKLYI
                     TDKLGHMLPPGACGELMITGWQVSRGYLNKPEKTAEVYTKNLYDDTPGYEVMYHSGDVA
                     RFLPDGNIQIIGRKDSQVKIR"
     aSModule        5..1420
                     /complete
                     /domains="nrpspksdomains_ctg130_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg130_1_PP-binding.1"
                     /locus_tags="ctg130_1"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       164..214
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg130_1_0001"
                     /evalue="8.50E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg130_1"
                     /protein_end="71"
                     /protein_start="54"
                     /score="21.5"
                     /tool="antismash"
                     /translation="LLYTSGSTGVPKGCMLE"
     CDS_motif       566..592
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg130_1_0002"
                     /evalue="4.80E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg130_1"
                     /protein_end="197"
                     /protein_start="188"
                     /score="6.8"
                     /tool="antismash"
                     /translation="YGPTEATIF"
     CDS_motif       695..781
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg130_1_0003"
                     /evalue="1.20E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg130_1"
                     /protein_end="260"
                     /protein_start="231"
                     /score="39.9"
                     /tool="antismash"
                     /translation="PPGACGELMITGWQVSRGYLNKPEKTAEV"
     CDS_motif       878..940
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg130_1_0004"
                     /evalue="9.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg130_1"
                     /protein_end="313"
                     /protein_start="292"
                     /score="33.8"
                     /tool="antismash"
                     /translation="IGRKDSQVKIRGFRIELSEVE"
     aSDomain        1238..1420
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg130_1_PP-binding.1"
                     /evalue="1.00E-10"
                     /label="ctg130_1_PP-binding.1"
                     /locus_tag="ctg130_1"
                     /protein_end="473"
                     /protein_start="412"
                     /score="33.9"
                     /tool="antismash"
                     /translation="DCIAEVLGYTDFGITTDIYEAGLTSITAIKLNILISKAFDIVIKT
                     SDIKNHPTIRMMEEFV"
     aSDomain        1457..2284
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg130_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.70E-38"
                     /label="ctg130_1_Condensation_LCL.1"
                     /locus_tag="ctg130_1"
                     /protein_end="761"
                     /protein_start="485"
                     /score="124.2"
                     /tool="antismash"
                     /translation="ESYPLTNTQEGIFIECTANMGSTIYNIPYLLKLDNKVDLDRLAEA
                     IDSTVEAHPYLKTRLFMDDNGNVLQKRNDGLSYKTPILNGMNRDTLVRPYMLFNEQLFR
                     FEIYRTCDGNYLFLDLHHIVADGTSLAIIINDINRAYSGEKLEPEGYTSYDLALDNRDA
                     LAGDIYKNAENYYKSVFEHAGGSISFYPDKNGAAPTAELYHRETRSISVQDVKEFCKKH
                     GITENVFFISAFGITLGKYNFKKDAVFTTIYHGRNDSRLSETVGMLVKTLPVFC"
     aSModule        1457..5263
                     /complete
                     /domains="nrpspksdomains_ctg130_1_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg130_1_AMP-binding.2"
                     /domains="nrpspksdomains_ctg130_1_PCP.1"
                     /domains="nrpspksdomains_ctg130_1_NAD_binding_4.1"
                     /locus_tags="ctg130_1"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       1523..1633
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg130_1_0005"
                     /evalue="1.50E-07"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg130_1"
                     /protein_end="544"
                     /protein_start="507"
                     /score="23.8"
                     /tool="antismash"
                     /translation="TIYNIPYLLKLDNKVDLDRLAEAIDSTVEAHPYLKTR"
     CDS_motif       1814..1879
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg130_1_0006"
                     /evalue="9.50E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg130_1"
                     /protein_end="626"
                     /protein_start="604"
                     /score="24.6"
                     /tool="antismash"
                     /translation="LHHIVADGTSLAIIINDINRAY"
     aSDomain        2729..3901
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg130_1_AMP-binding.2"
                     /evalue="6.60E-95"
                     /label="ctg130_1_AMP-binding.2"
                     /locus_tag="ctg130_1"
                     /protein_end="1300"
                     /protein_start="909"
                     /score="309.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FKEMAARYPDRPAVRDDSGDFTYRELDRMSDYIAQKLTENGFGPE
                     QAAGILCGRTKEYTVAYVGVMKAGGAYVPLDPEYPQSRIEYMLKDSGARNLLVIDQYQN
                     LVEFYDGNVISLDSVSDEAEDFELSAELISPKPENLAYMIYTSGSTGKPKGVMIEHRNL
                     LNLIEYITLSRNTSPDDIVAEFASFCFDASVIDLFAPLTAGAVLYILPESIRKDAIAIS
                     RYIKEKEITTVTFPTQMGELVTELLEDAPALKFVTLGGEKFKHYRNRTYQMINGYGPTE
                     NTVSSTEFWVDRQYDNIPIGKSQRNVRSYIVDENLNRLPVGASGELCHAGRQIARGYHN
                     LPEKTASVFVENPFAVCEQESRLYRTGDMVRMKGDGNIEYIGRIDSQVKIR"
     CDS_motif       2918..2956
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg130_1_0007"
                     /evalue="1.90E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg130_1"
                     /protein_end="985"
                     /protein_start="972"
                     /score="17.8"
                     /tool="antismash"
                     /translation="GVMKAGGAYVPLD"
     CDS_motif       3149..3208
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg130_1_0008"
                     /evalue="4.70E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg130_1"
                     /protein_end="1069"
                     /protein_start="1049"
                     /score="34.4"
                     /tool="antismash"
                     /translation="AYMIYTSGSTGKPKGVMIEH"
     CDS_motif       3557..3586
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg130_1_0009"
                     /evalue="5.50E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg130_1"
                     /protein_end="1195"
                     /protein_start="1185"
                     /score="6.7"
                     /tool="antismash"
                     /translation="YGPTENTVSS"
     CDS_motif       3686..3775
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg130_1_0010"
                     /evalue="1.20E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg130_1"
                     /protein_end="1258"
                     /protein_start="1228"
                     /score="40.0"
                     /tool="antismash"
                     /translation="PVGASGELCHAGRQIARGYHNLPEKTASVF"
     CDS_motif       3866..3931
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg130_1_0011"
                     /evalue="6.10E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg130_1"
                     /protein_end="1310"
                     /protein_start="1288"
                     /score="37.4"
                     /tool="antismash"
                     /translation="YIGRIDSQVKIRGYRVELGEIE"
     aSDomain        4217..4417
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg130_1_PCP.1"
                     /evalue="4.00E-21"
                     /label="ctg130_1_PCP.1"
                     /locus_tag="ctg130_1"
                     /protein_end="1472"
                     /protein_start="1405"
                     /score="66.9"
                     /tool="antismash"
                     /translation="RALCEIFEKALGIERVGIEDNFFELGGSSLTASKVAVMCLSKNIS
                     LVYADIFKYPTVRELAALVDDD"
     aSDomain        4550..5263
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg130_1_NAD_binding_4.1"
                     /evalue="2.90E-35"
                     /label="ctg130_1_NAD_binding_4.1"
                     /locus_tag="ctg130_1"
                     /protein_end="1754"
                     /protein_start="1516"
                     /score="113.4"
                     /tool="antismash"
                     /translation="VTGATGFLGIHVLKAFIDNYDGKVYCLVRKGKYESPEKRMMNMLM
                     YYFDDPYKELFESRIICVDGDITSKEQVTGFSEYKFSTIINCAACVKHFAADDVLERIN
                     VQGVENLIDFCKNNGRRLIQISTVSVAGEGSDGVPPMSRVFCENDLYIGQNITNEYIRT
                     KFLAERAVLEAVSEGLDGKVVRVGNLMSRNSDGEFQINFITNGFLRSLRGYAAVGKFPM
                     GGMHEVAEFSPIDSTA"
     CDS             5652..5954
                     /locus_tag="ctg130_2"
                     /transl_table=11
                     /translation="MEIITKTEGNKATMEISGWLDTQTAPQLGEALSGLEDSITSLVFD
                     FTNLEYISSAGLRQVIVAYKKMAQKDGFKIINVSDEVYDVFSLTGFDSKIDIQKK"
     CDS             5966..6613
                     /NRPS_PKS="Domain: ACPS (98-159). E-value: 2.8e-13. Score:
                     41.7. Matches aSDomain: nrpspksdomains_ctg130_3_ACPS.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012:4'-phosphopantetheinyl transferase (Score: 128.7;
                     E-value: 3.2e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg130_3"
                     /transl_table=11
                     /translation="MQKLYRININHFEDPLKNERLLDLVGIRRREKVIRYRMPDDRKRS
                     LGAGIIIRKILDENGLTESCLRYADNEKPVVDGLFFNVSHAGDYVVGVLSDCEVGCDIE
                     KNANAPLEVAEHYFYHSELAYIKAAKNKDKAFFTLWTLKESYMKMTGRGMSLPLDSFEV
                     VPTAEGFVLGKSSERPCFFETMEFDGYIFSVSSERAFSLHNPLEIVFDDIYV"
     aSDomain        6260..6442
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg130_3_ACPS.1"
                     /evalue="2.80E-13"
                     /label="ctg130_3_ACPS.1"
                     /locus_tag="ctg130_3"
                     /protein_end="159"
                     /protein_start="98"
                     /score="41.7"
                     /tool="antismash"
                     /translation="VGCDIEKNANAPLEVAEHYFYHSELAYIKAAKNKDKAFFTLWTLK
                     ESYMKMTGRGMSLPLD"
     CDS             complement(6628..7659)
                     /locus_tag="ctg130_4"
                     /transl_table=11
                     /translation="MNMIVKKMPILQGFPDFETVNFFTGKLFQKYNFTPVFYDIETTGL
                     SRNSTYLYLIGAVGIEDETWNFYQWMAENANEEETILRIFSQFLQQYNLMISYNGERFD
                     QPYLEARYEKYGIPSPFTGKQSLDLYLTLKPLKSLLKLPAMKQPCMEEFLGIKDRIYDN
                     GKECIKLYKDFLKKRDAFTADEILGHNLEDVLGLGRIFDMLGYLCIYDGDYEVTYSEFD
                     GDNLILKLKLPCTLPQEFSNGNTDFYLTGKDEEINLIIKTTDGKLKQYYADYKDYYYLP
                     EEDTVIPKSLGSGIDRKHRKAATRNTCYTWFTCSDAFLSSPVQQKQYLTYTLSCLIGTL
                     ERV"
ORIGIN
        1 gtacatgatg gaggattcct ctgcaaagct tctcattgct gacagagagc ttcttcctct
       61 ggtagacgga tataaaggac cggtgctgtt tacagatcag atctggcagc tggaggatag
      121 ggatgttgtg cttaagaagc cgcagctgca tgatctgttt atccttttgt atacttccgg
      181 ttccacaggt gtgccaaagg gctgtatgct ggaatatgga aatattactg ctttttgtca
      241 ctggttcaag agatattatg gcatagattc ggagtccagg atagctgcat atgcttcctt
      301 tggttttgat gcctgcatga tggatattta cggtgccatc acaaacggtg cacagcttca
      361 cattattccg gaggagatcc gtctggattt cattggactg cagcgctatt ttgaggaaaa
      421 tggcatcacg cattccttta tgactactca ggtgggaagg cagtttgcgc tggagatgga
      481 ttgtaagagc ctgagatatc tttctgtagg aggagagaaa ctggttccat gtgagccgcc
      541 aaaagattat aagtttatca atgcttatgg acctacagag gcgactattt ttacgactgt
      601 atttgaagtg gacaaatatt atccaaatgt cccgatcgga aaagcacttg acaatgtgaa
      661 gctttatatt acagacaagc tggggcatat gcttcctccc ggtgcatgcg gagagctgat
      721 gatcaccggc tggcaggttt ccagaggata tcttaacaag ccggaaaaaa ctgccgaggt
      781 ctatacaaag aatctttatg atgatacacc gggatacgaa gtgatgtatc attcaggtga
      841 tgtggcaaga tttcttccgg atggaaatat ccagatcatt ggcagaaagg attcccaggt
      901 taagatcaga ggtttcagga ttgagctttc tgaggttgag gaagtgatcc gcagatatga
      961 gggcatcagg gatgccactg tagttgcctt tgatgatcca aatggtggaa aatatattgc
     1021 tgcctatgtg gtatcggaca gcactgttga tatcaatgcc ctgaatgatt ttattaaaga
     1081 gacaaagcct gcctatatgg tacctgcagt taccatgcag attgacaaaa ttcctctgaa
     1141 ccagaaccag aaggtaaata aaaaggctct tcctctgcct gagaaaaaag cagcggagat
     1201 cattaagcct gagaatgagg ttcagcagat attatttgac tgtatcgcag aggttctggg
     1261 gtatacggat tttgggatta ccacagatat ttatgaggca ggtctgacat ccatcactgc
     1321 cattaagctg aatatcctga tctccaaagc ctttgacatt gtgatcaaaa cttcagatat
     1381 taagaatcat cccactatcc gaatgatgga ggaatttgta aaaactgcgg gaaaagaaag
     1441 caaaagagaa gtacaggaaa gttatcctct taccaacact caggagggga ttttcattga
     1501 gtgtacggca aatatgggtt ctaccattta caatatcccg tatctgttaa agcttgataa
     1561 caaggtggat ctggacagac tggcagaagc cattgacagt actgttgagg cgcatcctta
     1621 tctgaaaacc cgtctgttta tggatgacaa cggaaatgta cttcagaaac gaaacgatgg
     1681 gctcagttat aaaacaccga ttttaaacgg aatgaacaga gacactctgg tacgtccata
     1741 tatgttgttt aatgaacagc ttttccggtt tgaaatctac agaacctgtg atggcaatta
     1801 tctgttcctg gaccttcacc acattgttgc cgatggtaca tctctggcta ttataattaa
     1861 tgatattaac agagcttaca gcggtgagaa gctggaaccg gaaggttata cttcctatga
     1921 tctggcactg gataacagag atgccctggc aggtgatatc tataaaaatg cagagaatta
     1981 ttataagtca gtatttgaac atgcaggtgg aagcatcagc ttctatccgg acaaaaacgg
     2041 tgcggctcca acagcagaac tttaccacag agagaccaga tccatttctg tgcaggatgt
     2101 gaaggaattc tgtaaaaagc atggaattac ggagaatgta ttcttcattt ccgcttttgg
     2161 tatcacactt ggaaaatata atttcaaaaa ggatgctgta tttaccacta tttaccatgg
     2221 aagaaacgat tccagacttt cggaaacagt gggtatgctg gtaaaaacac tccctgtttt
     2281 ctgtgatttc tcaggaacag ctaaagattg cttaagcggt gtacagaaac agctgatcga
     2341 ttccatgaac aacgatattt atcctttctc acagatcagc catgagtttg atattaaggc
     2401 agatgccatg gttatttacc agggcgacaa ttttgctttt gacaccattg gcggggaata
     2461 tgcacaggag gagcctgtca gcctgaacat ggcaaaggca ccggtttctg tcagcatttc
     2521 cattgaaaag aacagatttg tctttgagat tgagtacaga ggggatatgt accatgagga
     2581 aactatccgg tatctggctg acaatctgga aaccactgca gagggaatct taagggaatg
     2641 cgatccggct gatatccggc tgatgtttga ggaagaaact cagatggagg atattccgga
     2701 acatgcagga aagaccttca tagatctgtt taaggagatg gctgccagat atccggacag
     2761 accggcagtg cgggatgact ccggagattt tacttacaga gagttggaca gaatgtctga
     2821 ttatattgct cagaagctta cggaaaacgg atttggcccg gaacaggcag caggtatcct
     2881 gtgcggcagg acaaaggaat atacagtagc ctatgtgggt gttatgaagg ccggcggagc
     2941 ctatgttcct ctggatccgg agtatccaca gagcagaatt gaatatatgc tgaaggattc
     3001 aggagcaaga aatctccttg tgatcgatca gtatcagaat cttgtggaat tttatgacgg
     3061 aaatgtgatc agtctggaca gtgtgtcaga tgaggctgag gattttgaac tttctgcaga
     3121 gcttatttct ccgaaaccgg agaaccttgc ctatatgatc tatacctcag gctccacagg
     3181 aaagccaaag ggtgttatga tcgagcacag aaatctgttg aacctgatcg aatatatcac
     3241 actgagcaga aatacttcac cggatgacat tgtggcagag tttgcgagct tctgtttcga
     3301 tgcgtcagtg atcgatctgt ttgcacctct taccgcagga gcagtcctgt atattttacc
     3361 ggagagtatc cgtaaggacg ccattgccat aagcagatat ataaaggaaa aagagatcac
     3421 caccgtaacc ttccctaccc agatgggaga actggttaca gaacttctgg aggatgcacc
     3481 tgctcttaaa tttgttacac ttggcggcga gaaattcaag cattaccgta accgtaccta
     3541 tcagatgatc aatggctacg gtcctacaga gaatacggtt tcttccacag agttttgggt
     3601 agacagacag tatgacaaca tcccgattgg aaaatcacag cggaatgtgc gcagctacat
     3661 tgtggatgag aatctgaacc ggcttccggt gggtgcgtcc ggcgaacttt gtcacgcagg
     3721 aaggcagatt gccagaggat atcataatct tccggaaaaa acagcatctg tgtttgtaga
     3781 aaatccattt gctgtatgtg agcaggaaag ccgtctttac aggaccggtg atatggtccg
     3841 catgaaaggt gacggaaata ttgagtacat aggccggatc gattcacagg tgaagatcag
     3901 aggatatcgt gtggagcttg gtgagatcga aggtgccctt ctgaaacatg agctggtgaa
     3961 aaatgcagcc gttacagtaa ttgaaaaggg tggaaataaa tatatcacag cttattatac
     4021 aggagaagcc atcccggagg atgaactgaa gaccttcctg gagccgctga tcccggatta
     4081 tatgatgccg tctttctttg tcagcattga ggaaatgcct gtgacaccgg gcggtaagat
     4141 tgataaaaaa gcactgccaa tgccggaggt aaccacgaac actgccagct atgtagagcc
     4201 ggttactgca gctcagagag cactctgtga gatttttgag aaagcactgg gaattgaaag
     4261 agtagggatt gaggacaact tctttgagct gggcggatct tcccttactg catccaaggt
     4321 tgctgttatg tgtctgtcaa agaatatttc actggtatat gcggatattt tcaaatatcc
     4381 tactgtacgg gaacttgcag ctctggttga tgatgacgga gttacagagg ctgcacagag
     4441 caagaatgaa ttttcggatt ataactataa caggatccag aatgtgatca gcgcaaatac
     4501 agaagaaaat gcagaccgga tcacaaagga aaagctggga gatattatgg tcacaggtgc
     4561 cacaggtttc ctggggatcc atgtccttaa agcattcatt gacaattatg acggtaaggt
     4621 ttactgtctt gtacgtaagg gcaaatatga atcgcctgaa aagcgaatga tgaacatgct
     4681 gatgtactat tttgatgatc catacaaaga gctgtttgaa agccgtatta tctgtgtgga
     4741 tggggatatt acctcaaagg aacaggtaac aggattttca gaatacaaat tcagcaccat
     4801 cattaactgc gctgcctgcg taaagcattt tgcggctgat gatgtactgg aaagaattaa
     4861 tgtgcagggt gtggaaaatc tgatcgattt ctgtaagaat aacggccgca gactgatcca
     4921 gatttctacg gtttccgttg cgggagaagg ttctgacggt gttccgccaa tgtccagagt
     4981 tttctgtgag aatgatctgt acatcggaca gaatattacc aacgaatata tccgcaccaa
     5041 attcctggca gagagggcgg ttctggaagc agtttccgag ggactggacg gcaaggtagt
     5101 ccgggtaggt aatctgatga gccgaaactc tgacggcgag ttccagatta atttcattac
     5161 caatggattc cttcgcagcc tgagaggtta tgcggctgta ggtaaattcc ctatgggcgg
     5221 tatgcatgag gtggcagaat tctcaccgat tgattctact gcgctggcag ttctgagact
     5281 ggctcagacc gaccggagat ttactgtatt ccatgcatgc aacagccatc atatttatat
     5341 ggcagacctg atttacgcaa tgcgcagcta tggattcagg attgatattg taagagatga
     5401 ggagtttgag gcagcagtga aggaatttgc aaagaccggt caggattctg atgcggtttc
     5461 cggactgatc gcctatacct cacataatga aaatgaaatc tataccattg attacagcaa
     5521 tcgttttaca gcacaggttc tgtacaggct ggattataaa tggccggtta cagatgacag
     5581 atatctggaa aatgcaattg cagcacttga cagacttaca ttttttgatt gattcaggag
     5641 ggaaaattac aatggaaatt atcacaaaaa cagaaggtaa caaggcaact atggaaatca
     5701 gcggatggct tgatacacag acagctcccc agttagggga ggctctgtcc ggacttgaag
     5761 acagcatcac aagtctggta tttgatttta caaatctgga gtatatttca tctgcaggct
     5821 tacgtcaggt gatcgtagcc tacaaaaaaa tggcccaaaa ggatggattt aagatcatca
     5881 atgtttctga tgaggtttac gatgtattca gccttacagg gtttgacagc aagatcgata
     5941 ttcagaagaa gtaactgttg atcagatgca gaaattatac aggatcaata ttaatcattt
     6001 tgaggatccg cttaagaatg aaaggcttct ggatctggtt gggatcagaa gaagagaaaa
     6061 ggtcatcagg tatcgtatgc ctgatgaccg caaaagaagt ctgggtgcag ggatcatcat
     6121 cagaaaaatc ctcgatgaaa acgggcttac ggaaagctgc ctgagatatg ctgacaatga
     6181 aaaaccggtt gtggatggcc ttttttttaa tgtatctcat gcgggggact atgttgtggg
     6241 tgtgctgtca gactgcgaag tcgggtgcga tattgagaaa aatgccaatg cgcctcttga
     6301 ggtggcagaa cattatttct accattcaga gcttgcttac atcaaggctg cgaagaacaa
     6361 agataaggcg ttttttacgc tctggacatt aaaagaaagt tatatgaaaa tgacaggcag
     6421 aggcatgagc cttcctttgg attcttttga agtggttccc acagcagagg ggtttgtcct
     6481 cggaaaatcc tcagaaaggc catgcttttt tgagacaatg gaatttgacg gttatatttt
     6541 ctcggtcagc agtgagaggg ctttttctct tcacaatcca ttggaaattg ttttcgacga
     6601 tatttatgta tgatcacaga tgatttttca gacacgctct agagttccaa tcagacagga
     6661 aagcgtatat gtcagatatt gcttctgctg tacgggagaa ctgaggaagg catcggagca
     6721 ggtaaaccag gtgtaacagg tatttctggt tgctgctttc cggtgctttc tgtcaattcc
     6781 ggatccgaga gatttcggga taaccgtatc ctcctccggg agataatagt aatccttata
     6841 atctgcatag tattgtttca gtttcccgtc agttgtcttg ataattaaat tgatttcttc
     6901 gtcttttcct gtcagataga agtcggtgtt tccattggaa aattcctgtg gcagtgtgca
     6961 ggggagcttc agcttcagga tcaggttgtc tccgtcaaat tcactgtatg taacttcata
     7021 atctccatca tagatgcaaa gatatcccag catatcaaaa attcttccca gtcccagcac
     7081 atcctccagg ttatgtccaa ggatttcatc agctgtaaag gcatctcttt ttttcagaaa
     7141 atctttgtaa agtttaatgc attccttacc attatcataa atcctgtctt tgatccccag
     7201 aaattcttcc atgcagggct gtttcatagc gggcagtttt aaaagtgact ttaacggttt
     7261 taatgtcagg tagagatcca gagactgttt tcctgtaaat ggagagggga ttccatattt
     7321 ttcatatcgt gcttccagat agggctggtc aaatcgttct ccgttgtaag aaatcatcaa
     7381 attatattgc tgaagaaatt gtgaaaaaat tctcagaatt gtctcttctt catttgcatt
     7441 ttccgccatc cattgataaa aattccaagt ttcatcttca attccaacag ctccgatcag
     7501 gtataaatac gtggaatttc ttgataatcc ggtggtttca atgtcgtaaa aaacaggtgt
     7561 aaaattgtat ttttggaaga gttttccagt gaaaaaatta acggtctcaa agtctggaaa
     7621 cccctgtaaa ataggcattt ttttaacaat catgttaata a
//
