LOCUS       gnlProkkaCJENKGDL_268  21975 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CJENKGDL_268.
ACCESSION   gnlProkkaCJENKGDL_268
VERSION     gnlProkkaCJENKGDL_268
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 22:38:37
            Original ID  :: gnl|Prokka|CJENKGDL_268
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 21975
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21975
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2:3500]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..3500
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..21975
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21975
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             complement(3..3500)
                     /NRPS_PKS="Domain: AMP-binding (22-421). E-value: 2.5e-105.
                     Score: 344.3. Matches aSDomain:
                     nrpspksdomains_ctg268_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (523-587). E-value: 4.4e-12.
                     Score: 38.3. Matches aSDomain:
                     nrpspksdomains_ctg268_1_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_LCL (599-880). E-value:
                     1.4e-38. Score: 124.5. Matches aSDomain:
                     nrpspksdomains_ctg268_1_Condensation_LCL.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     183.8; E-value: 1.1e-55)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg268_1"
                     /sec_met_domain="AMP-binding (E-value: 4.3e-109, bitscore:
                     355.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.7e-12, bitscore:
                     38.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 8.2e-49, bitscore:
                     156.7, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKMKNINERNNFVFEFRPVTELFEEQVKLHPEKCAVVSGKESFTY
                     AQLNERANRIANALVEKGVRRETIVGVVLERCCDFYAVRQGILKAGGAFAVATPDYPDD
                     RIRYIFEDSGAPFIITTKEIAEERRELFAKLPCTVLLIEELLENENTENPQVKIGEHDL
                     CYCIYTSGSTGKPKGVLIEHINLANFVNPDPKNAETYGYVSRGSVSLSMAAMTFDVSVL
                     EEFLPLTNGMTAVIASDEEILNPLMLGELIVRNKVDIMTTTPTYLSNMIDLPQLEKAVS
                     QIKVFDVGAEAFPPALYDKIRRVNPDAYIMNGYGPTETTISCTMKVITDSRNITIGTPN
                     GNVKVYIVDKENKILPDGETGELVIAGLGVGRGYMNLPDKTEAVFIDLNGERAYKTGDL
                     ARISPEGEIEFFGRIDNQIKLRGLRIELGEIEEVINSYEGIITSITLPVDNKFLCCYFM
                     ADRQINTEELSVYASESLAHYMVPEVFVQLEKMPVTQNGKIDKKALPKPAAQPKNLKEP
                     QTPMQKKIFEIVADVVENDFFGTDTSFYRAGLSSISAMKLCILISEEFGVTVKTSDIHE
                     NNTVEKLEKYVMLAPKIRTYEKREVYPLTGSQKGIFAECMKNPESTVYNIPFLFELESS
                     VDVQKLSDAISQMIAAHPYLLTKVYLSDSGEMVQKPCEEAFVPEVVRTTNEQFEKMKDE
                     LVRPFKLEKGRLFRAGIYVTEDRKYLFTDFHHILADGNSYDIIFEDIDRAYLGEKLEKE
                     SYTGFDAALDEEQQMKEGKYKKAEKYYDSIFEGIETESLPLPDCSGKTPERGYLSVPVD
                     TRESLVLSACEKLGVTPNILFTGVFGILMSRYSNSEESLFATIYNGRNDSRLENTVCML
                     VKTLPVYCSCDPKVTIQAYMTELSEQILSSMANDIFPFSDICAKYGINSDLVFAYQAEL
                     GDDFPIGDTVARGHDLSPDMSKMPLLIQVREYDHKYVLTAEYRSDMYSEAFVRGMLESY
                     EAAMDSLLKAKYISEVSVLSQNGADTIAEFNNTACEYDRSKTIADMFEELVQTIPDHTA
                     VVFKDKKYTYRELDEISDRLGKYIASQGIGSEDVVSILISRCEYMAIAPMGVIKAGAAY
                     QPLDPTYPRDRLRYMMEDSSAKLLIADRELLPLVDGYKGPVLFTDQIWQLEDRDVVLKK
                     "
     CDS_motif       complement(168..209)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg268_1_0007"
                     /evalue="2.00E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg268_1"
                     /protein_end="1111"
                     /protein_start="1097"
                     /score="14.7"
                     /tool="antismash"
                     /translation="MGVIKAGAAYQPLD"
     aSDomain        complement(861..1703)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg268_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.40E-38"
                     /label="ctg268_1_Condensation_LCL.1"
                     /locus_tag="ctg268_1"
                     /protein_end="880"
                     /protein_start="599"
                     /score="124.5"
                     /tool="antismash"
                     /translation="EVYPLTGSQKGIFAECMKNPESTVYNIPFLFELESSVDVQKLSDA
                     ISQMIAAHPYLLTKVYLSDSGEMVQKPCEEAFVPEVVRTTNEQFEKMKDELVRPFKLEK
                     GRLFRAGIYVTEDRKYLFTDFHHILADGNSYDIIFEDIDRAYLGEKLEKESYTGFDAAL
                     DEEQQMKEGKYKKAEKYYDSIFEGIETESLPLPDCSGKTPERGYLSVPVDTRESLVLSA
                     CEKLGVTPNILFTGVFGILMSRYSNSEESLFATIYNGRNDSRLENTVCMLVKTLPVYCS
                     "
     CDS_motif       complement(1266..1331)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg268_1_0006"
                     /evalue="1.10E-04"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg268_1"
                     /protein_end="745"
                     /protein_start="723"
                     /score="14.9"
                     /tool="antismash"
                     /translation="FHHILADGNSYDIIFEDIDRAY"
     CDS_motif       complement(1542..1637)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg268_1_0005"
                     /evalue="3.30E-06"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg268_1"
                     /protein_end="653"
                     /protein_start="621"
                     /score="19.5"
                     /tool="antismash"
                     /translation="TVYNIPFLFELESSVDVQKLSDAISQMIAAHP"
     aSDomain        complement(1740..1931)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg268_1_PP-binding.1"
                     /evalue="4.40E-12"
                     /label="ctg268_1_PP-binding.1"
                     /locus_tag="ctg268_1"
                     /protein_end="587"
                     /protein_start="523"
                     /score="38.3"
                     /tool="antismash"
                     /translation="KIFEIVADVVENDFFGTDTSFYRAGLSSISAMKLCILISEEFGVT
                     VKTSDIHENNTVEKLEKYV"
     aSModule        complement(1740..3434)
                     /complete
                     /domains="nrpspksdomains_ctg268_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg268_1_PP-binding.1"
                     /locus_tags="ctg268_1"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(2208..2273)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg268_1_0004"
                     /evalue="2.10E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg268_1"
                     /protein_end="431"
                     /protein_start="409"
                     /score="32.7"
                     /tool="antismash"
                     /translation="FFGRIDNQIKLRGLRIELGEIE"
     aSDomain        complement(2238..3434)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg268_1_AMP-binding.1"
                     /evalue="2.50E-105"
                     /label="ctg268_1_AMP-binding.1"
                     /locus_tag="ctg268_1"
                     /protein_end="421"
                     /protein_start="22"
                     /score="344.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEEQVKLHPEKCAVVSGKESFTYAQLNERANRIANALVEKGVRRE
                     TIVGVVLERCCDFYAVRQGILKAGGAFAVATPDYPDDRIRYIFEDSGAPFIITTKEIAE
                     ERRELFAKLPCTVLLIEELLENENTENPQVKIGEHDLCYCIYTSGSTGKPKGVLIEHIN
                     LANFVNPDPKNAETYGYVSRGSVSLSMAAMTFDVSVLEEFLPLTNGMTAVIASDEEILN
                     PLMLGELIVRNKVDIMTTTPTYLSNMIDLPQLEKAVSQIKVFDVGAEAFPPALYDKIRR
                     VNPDAYIMNGYGPTETTISCTMKVITDSRNITIGTPNGNVKVYIVDKENKILPDGETGE
                     LVIAGLGVGRGYMNLPDKTEAVFIDLNGERAYKTGDLARISPEGEIEFFGRIDNQIKLR
                     "
     CDS_motif       complement(2346..2435)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg268_1_0003"
                     /evalue="1.00E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg268_1"
                     /protein_end="385"
                     /protein_start="355"
                     /score="37.0"
                     /tool="antismash"
                     /translation="PDGETGELVIAGLGVGRGYMNLPDKTEAVF"
     CDS_motif       complement(2952..3011)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg268_1_0002"
                     /evalue="5.90E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg268_1"
                     /protein_end="183"
                     /protein_start="163"
                     /score="31.1"
                     /tool="antismash"
                     /translation="CYCIYTSGSTGKPKGVLIEH"
     CDS_motif       complement(3219..3245)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg268_1_0001"
                     /evalue="2.90E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg268_1"
                     /protein_end="94"
                     /protein_start="85"
                     /score="5.3"
                     /tool="antismash"
                     /translation="GILKAGGAF"
     CDS             complement(3508..5253)
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 265.5; E-value: 1.3e-80)"
                     /gene_kind="transport"
                     /locus_tag="ctg268_2"
                     /transl_table=11
                     /translation="MEERNNRLLNAKLNKYIVPGIMMSLALQLGNIVDTIFVSNLIGVE
                     AMSAVTLSLPVETIVQLTGYCLGIGGSIAVGNMLGKRDKEGASKLFSATFIVTLVVGII
                     FSICALPAAEPVARLLVSGDGVLTGYTRDYIRVSMLGAPVIGIGLMMVNYLGVENHPEL
                     ASAYLIAANVINLVLDYIFLRYTPLGITGASLSTVLGFLFAMGIFVLYIRSDKRNLHLI
                     LLKPGELGITKEAIITGVPMLIFMAANFVKALGLNTIIMNQLGEEGMAVFTVCDNVLLI
                     VEMLTGGIIGVIPNVAGILFGEKDYVGIRVLCKKMLKYSYILLAVIFVLIMLFTEEITV
                     MFGSGGGELGSHMVQALRIFALCVAPYLWNKFIISYYESIEETAIASFATFLENAVVVL
                     PATLVGILVWKQIDGIGIDGIAVGFVATEIITAVAACIFRKIRHKNTSFYIVPDKNPGI
                     NLDFSIKSTMEEAQTVHKRIIEFCQEQGASKSKANLAAVCAEEMTVNIIRFGGKTSNWI
                     DINLCLEDDLCRLRIRDNGVNFNPLEYQYDSEDFDIHGIELVKKVSKSMDYIRAIDMNN
                     TIISF"
     CDS             complement(5386..6813)
                     /locus_tag="ctg268_3"
                     /transl_table=11
                     /translation="MDSTKPENLISYTNIEVDGIVTFRGNSFRDTPSHGYADMTDFRLN
                     KLWSADTGSLSSGSAVWTGSGWTGQPLMMKWPKEVKAHMNMTEKAKADDELVEVIYACM
                     DGYVYFLDLRTGEKTRDPLYLGYTFKGAGALDPRGYPIMYVGAGYNSNEGTAKVFVVNL
                     LDCSVMYTFGDNDEFSLRGSLSFFDGSALVDAETDTLIYPGENGILYLIRLNTKYDLNS
                     GTLSIDPGRTVKWRYYGTRSSTESFWLGMEDSAAIYKGYIFMTDNGGNLMCLDLNTLQL
                     VWVQDTLDDSNSTPVLEIEKGHLYLYVSTSFRLGWRSYDTATVPVWKIDAETGEIVWHT
                     DYECTTDDGVSGGVQSTIACGKNSLADYIYVTVAKTSDNASGVLACLRKSDGSKAWEDS
                     SSYAWSSPVCVYNKDGLGKVLYCNSTGDIRLLDGKTGKQEDVLSVSEGVIEASPAVYDN
                     YAVVGTRDCKIWGIRLQ"
     CDS             complement(6854..7246)
                     /locus_tag="ctg268_4"
                     /transl_table=11
                     /translation="MQQRQGYQAVEKLRETLDEKYLWEVILLYAGESFKTYTGLPFTYE
                     VRKGRNGDYTRELWIDRRENSKSLALSSVLLALRNIKKVGAVVDRPKALGDIRGVSYIY
                     GMFYRFGLIDVPDTARQKMKFTGYIF"
     CDS             complement(7305..7403)
                     /locus_tag="ctg268_5"
                     /transl_table=11
                     /translation="MSINRNEYKYICPNQKDKLGRADYGNDFSNAL"
     CDS             complement(7400..8236)
                     /locus_tag="ctg268_6"
                     /transl_table=11
                     /translation="MLYIGNHTSSSRGYLAMGKQMLANGGNTFAFFTRNPRGGKAKDID
                     PQDVQAFGQLAEENHFGKLVAHAPYTMNCCAAKENLRDFAREIMADDLRRLEMTPGNYY
                     NFHPGSHVGQGAEVGISKIAEILNEVLTKDQSTIVLLETMSGKGTEVGRNFEELRQIID
                     RVELKDKLGVCLDTCHVWDGGYDIVNDLDSVFEEFDRIIGLDRLKAIHLNDSMNPLGSH
                     KDRHARIGEGEIGLEALVRVINHPATEGIPFILETPNDDEGWTHEIALLRNEYKQK"
     CDS             complement(8502..9062)
                     /locus_tag="ctg268_7"
                     /transl_table=11
                     /translation="MDIYQIIITHNRSWTIREIIAFAVVFLMAVFLAAVLLRLHKIVII
                     QAVCGLLLLTFFAIVFGSTVFTRTPGIRQYQPEVFWSWKEILGIGTCGRLGSTTGDGLL
                     QENLLNILLLFPAGILLPGLTGRKLKWWMGLLVGIAVSSAIEISQLLLCRGLFEFDDII
                     HNSLGCMLGCLLGNRMLRLVHGK"
     CDS             complement(9313..9558)
                     /locus_tag="ctg268_8"
                     /transl_table=11
                     /translation="MPDAYDHISLICRLKATQTKNKELESGERYVKLNELHQKECRAYE
                     HKIQALQTEVADAHKETIRVRNYWFQVLRNTLGQTP"
     CDS             9720..10076
                     /locus_tag="ctg268_9"
                     /transl_table=11
                     /translation="MYNFFTKVIHRILSILSDRGLISAHFQSYNGDLSTVRLPNGSFPG
                     IRFFPAFLLYFFQEREVVFMEIDFIQELKKRDELLDGYLRQIEIQEEFIQKQKELIEYL
                     EDHISKITDIVSSV"
     CDS             10101..11345
                     /locus_tag="ctg268_10"
                     /transl_table=11
                     /translation="MPDTYDHITLMCRLKAAQRRNKELESGERYIQLEELYQKEYNVYE
                     HKIEKLKKELADAHKETIRVRNYWFQILEDMLREFEKAQKRSAQELRKMEIRALNAEKQ
                     RDDALDKAAVFRHQFYEAASRLEEEQGKNLKLRAQINRDYENSSIPSSKAVRRKKITNN
                     REKTGRRPGGQPGHKGHCRKRQEPTQPVILLPPPEEALEDCAFKKTARTIVKQMVSIRM
                     VLNVTEYHADVYYNSHTGERAHAAFPDGVIDDVNYDGSIRAFLFLLNNDCCTSIDKSRA
                     FLSDLTGGKLNISKGMISRLNREFALKTEPEHRSAYADMLLSPVMHTDCTNARENGKSC
                     QIYVCATPDGKALYFAREKKGHEGVKGTVTEDYQGILVHDHDITFYNYGADHQECLAHV
                     LRYLKASIENEPDRT"
     CDS             11355..11774
                     /locus_tag="ctg268_11"
                     /transl_table=11
                     /translation="MHALVQEMVHFRNGCRQPHGPDPEIVSGFEKRYREILETARKEYE
                     NIPANDYYKDGYNLFLRMEKYMHNHLLFLHDIRVPATNNEAERLLRNYKRKQAQAVTFR
                     SFESIDYLCQCMSMLVLMRLEDPANIYDRVSRIFG"
     CDS             complement(11939..12085)
                     /locus_tag="ctg268_12"
                     /transl_table=11
                     /translation="MFAPVPVVIKIAYLVETTDLFCYGITDNSERITAFRYNVMKSYND
                     FRR"
     CDS             12098..12217
                     /locus_tag="ctg268_13"
                     /transl_table=11
                     /translation="MTIGNQTKDYTFCPDVSTGDIEEIQKINFMDTSKMTKIY"
     CDS             complement(12265..12744)
                     /locus_tag="ctg268_14"
                     /transl_table=11
                     /translation="MKRKRFSRLLFLMLTIMITVTFYQPAQAASGKYTGTYTKTWSVSS
                     NMTVTIKPSYSVIVNKVTSTKVRLQLEKLGVNGSPIYATAPITAKRKGNTVSFKWKDTW
                     GNSGTGTLKLYKGYVKLKVKQTYTARWNRSTLDTSGKYMKIYRKSGNTKMDNIDL"
     CDS             complement(12876..13289)
                     /locus_tag="ctg268_15"
                     /transl_table=11
                     /translation="MCSRYYIDPGMTEDISRVVQNIDGRIWLAQGDTRPTDVAPVIGQS
                     EHGLELGICRWGYPLSKSKGLVINARVETVLDKPSFQNGILYHRLLIPAGGFYEWNSLK
                     EKSIFTRLDSSVLYMAGFCDWFDNSKMPVLLQA"
     CDS             complement(13446..14201)
                     /NRPS_PKS="Domain: PKS_KR (6-175). E-value: 2.3e-15. Score:
                     48.8. Matches aSDomain: nrpspksdomains_ctg268_16_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     243.4; E-value: 4.2e-74)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg268_16"
                     /sec_met_domain="adh_short (E-value: 2.1e-39, bitscore:
                     125.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.8e-36, bitscore:
                     116.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENKVAIITGSTRGIGRATAELFAKEGAKVIVVGTKEELGESC
                     VNAIKAAGGEAIFCKTDVTSDESLDNLVKTALDAYGKIDILVNNAGVGGTTANMDQITM
                     DEWNTVLATNLTAPFVLCKKLIPIMEKQGAGTIVNVASMAATAAGRGGLAYTSAKHGLL
                     GLTRQMSLDHGRTGVRINAVLPGPIATDMIARVLAIPQHPVTMKIGMSPAKRPGEPIEV
                     AQAIAFLASDEASFIHGAALAVDGGYTIF"
     aSDomain        complement(13677..14183)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg268_16_PKS_KR.1"
                     /evalue="2.30E-15"
                     /label="ctg268_16_PKS_KR.1"
                     /locus_tag="ctg268_16"
                     /protein_end="175"
                     /protein_start="6"
                     /score="48.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAIITGSTRGIGRATAELFAKEGAKVIVVGTKEELGESCVNAIKA
                     AGGEAIFCKTDVTSDESLDNLVKTALDAYGKIDILVNNAGVGGTTANMDQITMDEWNTV
                     LATNLTAPFVLCKKLIPIMEKQGAGTIVNVASMAATAAGRGGLAYTSAKHGLLGLTRQM
                     SLDHGR"
     CDS_motif       complement(14097..14177)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg268_16_0001"
                     /evalue="2.70E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg268_16"
                     /protein_end="35"
                     /protein_start="8"
                     /score="20.0"
                     /tool="antismash"
                     /translation="IITGSTRGIGRATAELFAKEGAKVIVV"
     CDS             complement(14215..17025)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     377; E-value: 1.4e-114)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg268_17"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7e-30, bitscore:
                     94.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYQEIFKQGKIGNITLKNRLVMSPMGTSLAEMDGSPSEDMIAFYE
                     ARAIGGAALIIPEIARVNDLHGAGMMRQLSVSKDRHIEGLAKLAETVHKYGTKIFIQLH
                     HPGRETVTALTGGPVVSASAIPCKYLQQETRALSTEEVKALIQQFISGAVRVKKAGCDG
                     VELHAAHGYLLQQFLSPYTNKREDEYGGSFENRLRMITEIINGIRVQCGPDFPIGVRLS
                     VEEFLDKTGVTEDYIHIQDGVKIAMALEKCGIDFIDVSVGLYETGSVCVEPISFPQGWR
                     KDLIKAVKDHVSIPVIGVSCIREPQVAESFLEGGIVDFVSMGRSWLADEQWGLKVLEGR
                     ENEICKCINCLRCFESLNAWMGAGIPAECAVNPRAGRERLEGNAEYDTQEQKAAVVGGG
                     PCGMIAAKTLAERGMKVTLVDRQSELGGTINLAKKPPFKERMGWIADYYNVEFEKLGVE
                     LKLDMEATADKIAEMNPDAVLVATGSKSVIPGSIPGITGENVYTIEDILSGKAGLKNKK
                     VMIIGAGVTGLETAEYLCHEGNTVVLADMLDKVAPNANHTNVADVCGRLKEYNAQFMMA
                     YALKEIKKDGVVLERLNDKINVEVAADAVVLSLGFRPDNHLVEELKEKGIHAQAIGNAV
                     KDGTIAPASRSGFEAARKLFKTSVKTPSFITAPEEMPNFGKISLMKNQEGIYLAYLTDP
                     AAIAKVLPAPLKPFSVPVVTVSVCHVKEPTFADDYYEAILGVYCTYGTQLGLYPIGLVL
                     GGTGAEMAVQCGRDNGSIPKKLGSEFVIRRNNDHVTAQVCRRGTELVNIDLKIGEYNNA
                     MTGMLYQFPEAGKKTYGGGFYFHLDREPDKEGKSHFQNGALLQNLCEYNYHSWEPGFAA
                     IKLQSSIDDPWGELPIRTVIGGAYSSNDLMVHKLNLCEEIDADVLAPYLLTARYDRTAF
                     METGRR"
     CDS             complement(17006..17176)
                     /locus_tag="ctg268_18"
                     /transl_table=11
                     /translation="MHSVLQIIINYSALCINTQCLFYIYAVVFLTMKMLFLSHNNQETQ
                     VKEGVHVSGNI"
     CDS             17210..18778
                     /locus_tag="ctg268_19"
                     /transl_table=11
                     /translation="MLFSDLIDYLKNEKTFNIILNCSTDLHEIRDVELLDGTQTGYATD
                     IVYFGYPDVLSPDMQPSQCILVRGENYLFPYSCTDRATVQAKELFAVFNAAKQFLQTHE
                     QVSLYEELVRKGHSSHSLDEVINSASIKLGYSLVFCDKKFRILSFSTSIPVTDKLWKEN
                     IERGYCTYDFIKNVMSLEAVQGASASIEAVEVSCPESPYRKCSSKVFLNGVQVGFVLMI
                     ENNIPFTAEHLAAMSDVSRAISSVVGHYHPELFQYTSADQQLLEALLIGTPADILAESI
                     SHLRVSDAMYALCIQPKTFLKENELKQQLYPVIRHIFPEAYMTVHDNALVLLVPDQSSV
                     IFVDTQKVMLKTMAEYHLDVGISLVFSKMDEFYRAYQQARTVLEWNHRIPDNLKKEISW
                     DQRYPMEHQIHRYSEIEFYEMMNKIKEPEKLADYIHPALYRLNKYDQRTGNELYHTLEV
                     YLQCFHNNKETANILCIHRNSLAYRMEKIIEIGKADLNDPMTEFLLRMSFKLVEYLKIR
                     DLDLP"
     CDS             complement(18903..20729)
                     /locus_tag="ctg268_20"
                     /transl_table=11
                     /translation="MQVTKTVEETRKQIKAWKKEGKTIGLVPTMGFLHEGHASLIKKCR
                     EQNDIVVVSDFVNPTQFGPTEDLEAYPRDFERDSKLCESLGTDLIFCPEPSEMYHDPHA
                     FVSIDTLSETLCGKTRPIHFKGVCTVVTKLFHIVAPDRAYFGQKDAQQLAIIRKMVQDL
                     NFDIEIVGCPIVREEDGLAKSSRNTYLSDEERKAALCLSRSVKLGQEIIHAGISAEELL
                     GKMRAVIEAEPLAKIDYVSMVDALTMQPVEKADHNVLVAMAVYIGKTRLVDNFSYEVYY
                     LENILKKIGKISSFASRYIGIIIIAFSCLAFFWRDGFAWMTNYTSVFLGVIMFGMGLTI
                     RLEDFRAIFSRPKEVIIGAVAQYTIMPVVAWVLCKVMNLPADLALGVILVGCCPGGTAS
                     NVITYIAGGDVALSVGMTIVSTLAAPVMTPFLVYILAGAWVEVSFWAMVLSVVKVILVP
                     VLLGILLRTLAGDHVDKVSDVMPLISVVAIVMIIGGIVAINAEKILSCGVLVLGVVAIH
                     NFCGMMLGLLAAKIFHVEYTRATAIAIEVGMQNSGLAVSLAAANFVANPLATLPGAIFS
                     VWHNIAGSIFAGIRRSGVENRTRTGENGVSAA"
     CDS             complement(20839..21330)
                     /locus_tag="ctg268_21"
                     /transl_table=11
                     /translation="MYPDALFLQIIKVYFLFMVLLDSDFSRRKGLYKMTIEMLKGKIHR
                     ATVIQAELDYVGSITVDEELLEAAGILEYEKVQIVDVNNGSRFETYTICGKRGSGMICL
                     NGAAARCVSTGDKIIIMAYAGYEPEEARIHKPAVVFVDEENKISRVTNYEKHGLLKDMA
                     "
     CDS             complement(21622..21873)
                     /locus_tag="ctg268_22"
                     /transl_table=11
                     /translation="MPYEVFRKNFFAHMNELEITPGKVRLDEAIRLIVCQMSDFLVPYV
                     ISINYVCEANDTPLALHKEIHIYCISQCITGRGVNSNQ"
ORIGIN
        1 ggcttcttaa gcacaacatc cctatcctcc agctgccaga tctgatctgt aaacagcacc
       61 ggtcctttat atccgtctac cagaggaaga agctctctgt cagcaatgag aagctttgca
      121 gaggaatcct ccatcatgta cctcaggcgg tccctgggat aggttggatc cagaggctgg
      181 taagctgcac ctgcctttat cacgcccatc ggtgcgatcg ccatatattc acagcgggag
      241 atcagaatgg aaacaacatc ttcactgccg attccctggg atgcgatata ttttccaagt
      301 ctgtcactga tctcatccag ttctctgtaa gtatattttt tatccttaaa taccacagcc
      361 gtatggtcag gaatggtctg taccagctcc tcaaacatat cagcgatggt cttacttctg
      421 tcatattcgc aggcagtatt attaaattcc gcaattgtgt ccgctccatt ttgagaaaga
      481 acagaaactt ccgaaatata ttttgctttc agcagggaat ccatagctgc ctcataggat
      541 tccagcattc cacgtacaaa ggcttcactg tacatgtcac tgcggtattc tgcagtaagc
      601 acatatttat gatcatattc tcttacctga atcagcagag gcatctttga catatccgga
      661 gaaaggtcat ggcccctggc aacagtatca ccaatcggaa aatcatcccc aagttctgcc
      721 tgatatgcaa ataccagatc agaattaatc ccgtactttg cacagatatc agagaacgga
      781 aaaatatcat ttgccatgga agacagaatc tgctcagaga gctctgtcat ataggcctgt
      841 atggtgactt tcggatcaca ggaacagtaa accggcagag tctttacaag catgcagact
      901 gtattctcca gtctggaatc atttcttcca ttataaatag ttgcaaaaag actctcctcg
      961 gaattggaat atctgctcat gagaatgccg aatacacctg taaacagaat gtttggagta
     1021 acccccagct tctcgcaggc agaaagtacc agagactctc tggtgtccac aggcaccgac
     1081 agatatcctc tctcaggagt ctttcctgaa cagtcaggaa gaggcaggga ttctgtctca
     1141 attccctcga aaatactgtc ataatatttc tcggccttct tatattttcc ctctttcatc
     1201 tgctgttctt catcaagggc agcatcaaag cctgtgtagg attctttctc caatttctca
     1261 cccagatagg cccgatcgat atcctcaaaa ataatatcat aggaattacc atctgccagg
     1321 atatggtgga aatctgtaaa aagatatttc ctgtcttctg tcacataaat ccccgcccgg
     1381 aacagccgtc ccttttccag cttaaaggga cgcaccagct catctttcat cttttcaaac
     1441 tgctcatttg tggtccggac cacctctggt acaaaggctt cctcacaagg cttctgcacc
     1501 atctctccgc tgtcacttaa ataaaccttt gtcagcagat acggatgtgc agcgatcatc
     1561 tgagaaatgg catctgacag cttctgaacg tcaacagagc tttccagttc aaacaggaac
     1621 ggaatattgt ataccgtact ctcaggattc ttcatgcact ctgcaaaaat acccttctgg
     1681 gagccggtaa gagggtaaac ttctctcttt tcataggttc tgatcttcgg tgcaagcatc
     1741 acatattttt ccagcttctc caccgtattg ttttcgtgga tatcactggt tttcacagtc
     1801 actccgaatt cctctgagat cagaatacaa agcttcatgg cactgataga agacagcccc
     1861 gccctgtaaa aacttgtgtc agttccaaaa aaatcattct ccacaacgtc tgcaacgatt
     1921 tcaaaaatct tcttctgcat aggagtctgg ggttctttca gattctttgg ctgtgcagcc
     1981 ggctttggca gtgctttctt atcaatttta ccattctgtg tcacaggcat cttttccagt
     2041 tggacaaaaa cctcaggaac catataatga gccagggact ctgatgcata gacagaaagc
     2101 tcctctgtat tgatctggcg gtcagccata aaatagcagc agaggaattt gttatctaca
     2161 ggcagagtaa tgctggtaat gattccctca taggaattga tcacttcctc gatctcacca
     2221 agttcaatcc tcaggccgcg aagcttgatc tgattgtcta ttcttccgaa aaattcaatc
     2281 tcaccctcag ggctgatcct tgcaaggtca ccggtcttat aagctctctc tccgttaaga
     2341 tcaatgaata cagcctctgt tttatccggc agattcatat aacctctgcc aacgcccagt
     2401 cctgcgatca caagctctcc ggtctctccg tccggaagga tcttattctc tttatctaca
     2461 atatatacct tcacattacc gttaggcgta ccaatggtaa tgtttctgct gtccgtaatt
     2521 accttcatgg tacagctgat ggtagtttcc gtaggtccat aaccattcat aatgtaagca
     2581 tccgggttta ctctgcgaat cttgtcatac agagccggag gaaaagcctc tgcacctaca
     2641 tcaaacacct taatctgaga aactgctttt tcaagctggg gcagatcgat catattggac
     2701 agataagtag gagttgtggt cataatatcc actttatttc tgacgatcag ctcacccagc
     2761 ataagaggat tcagaatctc ctcatcagag gcaatcaccg cagtcatccc gttggtaagt
     2821 ggcagaaatt cctccagaac agacacatca aaggtcatgg ctgccatgga aagagataca
     2881 cttcctctgc ttacataacc ataagtttcc gcatttttcg gatccggatt tacaaaattg
     2941 gcaaggttga tatgttcgat cagcacaccc ttgggcttgc ctgtggaacc ggaagtatag
     3001 atacaataac aaagatcatg ctccccgatc tttacctgag gattctctgt attctcattc
     3061 tccagaagtt cctcgatcag aagtactgta cagggaagct tagcaaacag ttcccttcgt
     3121 tcctctgcga tctcctttgt tgtgataata aaaggagctc ctgaatcctc aaaaatatac
     3181 cggatcctgt catcaggata atccggtgtg gcaactgcaa atgcgcctcc tgccttcagg
     3241 ataccctgcc gcactgcata gaaatcacag catctctcaa gaaccacacc tacgatggtc
     3301 tcccgtctga cacctttttc cacaagtgca ttggcaatcc tgttggcccg ttcattgagc
     3361 tgtgcatagg tgaagctctc tttgccggag acaactgcac atttctctgg atgaagcttc
     3421 acctgttcct cgaacaattc tgttaccggc cgaaactcaa atacaaaatt gttcctttca
     3481 ttaatatttt tcattttcat gtacctccta aaaagatatt atggtattat tcatatcaat
     3541 cgcacgaata taatccatgg attttgatac cttcttgaca agttcaatcc catgtatatc
     3601 aaagtcttca ctgtcatact gatattccag agggttgaaa tttacaccgt tatctctgat
     3661 cctcagtctg cagagatcat cctccagaca gaggttaatg tcgatccagt tggaggtttt
     3721 tcccccgaat cgtataatat ttacagtcat ttcctccgca cacactgcgg caagatttgc
     3781 cttgctttta gaagctccct gttcctggca gaactctatg atccgcttat gaaccgtttg
     3841 tgcttcctcc atggtactct taatggaaaa atccagatta atccccggat ttttgtcagg
     3901 aacaatataa aagcttgtat tcttatgcct gatttttctg aaaatacagg ctgcaactgc
     3961 agttatgatc tcagttgcaa caaatcccac tgcaattccg tcgataccga tcccgtcaat
     4021 ctgtttccat acaaggattc ccaccagggt tgcaggcaga actaccaccg cattctccag
     4081 aaatgtggca aaacttgcaa tggctgtctc ctcaatggac tcgtaatagc tgataataaa
     4141 cttattccac agataaggtg ccacacacaa agcaaagatt cgcagcgcct ggaccatatg
     4201 actgcccagc tcgccaccgc cgcttccgaa catgacagtg atttcctcgg taaacagcat
     4261 aataaggaca aaaatcacag ccagcaggat gtaactgtat ttcagcatct ttttacagag
     4321 aacccggatt cccacatagt ccttctctcc gaaaagaatt cctgccacat tggggatcac
     4381 accgatgatt ccgcctgtaa gcatctcgac gatcagcagc acattgtcac agacagtaaa
     4441 tactgccata ccttcctcgc ccagctggtt catgataatg gtattcagtc caagcgcctt
     4501 tacaaaatta gctgccataa agatcagcat tggcacgcct gtgatgattg cttcctttgt
     4561 gattccaagt tcgcccggct ttagcaggat caggtggagg tttcgcttat cagagcggat
     4621 ataaagcaca aaaattccca ttgcaaacag gaaaccaaga acagttgata aggatgcacc
     4681 tgtaatcccc agaggagtat atctgaggaa tatatagtcc agcacaagat tgatcacatt
     4741 ggctgcgata aggtaggctg atgccagctc cggatgattc tccacaccaa gataattgac
     4801 catcatcagt ccaattccga tcaccggtgc ccccagcata cttacacgta tgtaatctct
     4861 ggtataaccg gtcaggacac cgtcacctga taccagaagt ctggcaacag gttctgctgc
     4921 aggaagggca cagattgaaa aaatgattcc caccacaagt gttactataa atgtggcaga
     4981 aaacaatttc gatgcccctt ctttgtctcg tttgccaagc atgtttccca ctgctatgga
     5041 accgccgata ccaaggcagt atcctgtcag ctgaacgatc gtctccacag gcaggctcag
     5101 ggtaactgca gacattgcct ccaccccgat caggttactt acaaatatcg tatctacgat
     5161 atttcccagc tgaagcgcca gagacatcat aatccccgga acaatatact tgttcagctt
     5221 cgcattcagc agtctgttat ttctctcttc catcgcttcc tctcctttgt tttcagtttt
     5281 ttcaaaatat tgtgccgtaa aactgtaaga tatttaaatt ttaccattta gtgcgataaa
     5341 tggcaagtta ataaagaatg ggagaaagca aataaatatt gctatttact gtaacctgat
     5401 tccccatatt ttacagtctc tggtgcctac aaccgcatag ttatcgtaga cagccgggga
     5461 agcctctatc acaccctcgc tgacagataa tacatcttcc tgtttacctg ttttaccatc
     5521 aagaaggcgg atatcacctg tactgttgca ataaagaacc tttcctaatc cgtctttgtt
     5581 ataaacgcac accggagaag accaggcata tgaggaagaa tcctcccatg ctttagatcc
     5641 gtcagatttt ctcagacagg caagaactcc ggatgcattg tcagaggtct ttgccactgt
     5701 cacatatata taatcggcaa gactgttctt tccacaggca atcgtagact gaactccacc
     5761 ggaaacaccg tcatcagtag tacattcata atctgtatgc cacacgatct caccggtttc
     5821 tgcatcaatc ttccagacag ggacagtggc tgtgtcataa cttctccatc caaggcggaa
     5881 ggaagtactt acatacagat acagatgtcc tttttcgatt tccagaacag gcgttgaatt
     5941 agaatcatcc aatgtatcct gaacccatac cagctgaaga gtgttcagat ccagacacat
     6001 aagatttccc ccattatcgg tcataaatat atagccttta tagattgccg cactgtcttc
     6061 cattccaagc cagaaagact ctgtactgct tcttgttcca tagtagcgcc attttacagt
     6121 tctgcccgga tcaatggata aagtcccact gttcagatca tattttgtat tcagcctgat
     6181 cagatacagg attccgttct ctcccggata gatcagggta tctgtctctg catccacaag
     6241 tgctgatccg tcaaaaaagc tcagacttcc tctgagtgaa aactcatcat tgtctccaaa
     6301 agtatacata acactacaat ccagcaagtt tactacaaat acctttgcag ttccttcgtt
     6361 gctgttatat ccggcgccaa catacataat cggatatcct ctcggatcaa gggcacccgc
     6421 acccttaaaa gtatatccca gatataatgg gtcacgtgtc ttttctcccg ttctcagatc
     6481 cagaaaatac acatacccat ccatacaggc ataaatcacc tcaaccagtt catcatctgc
     6541 ctttgctttc tctgtcatat tcatatgtgc tttgacctct tttggccatt tcatcataag
     6601 cggctgtcct gtccagccac ttcctgtcca gactgcactg cccgaagaaa gagaacctgt
     6661 atctgcagac cacagtttgt tcagcctgaa atcagtcata tctgcataac catgggaagg
     6721 ggtatcgcga aaactgtttc cgcgaaatgt gacgattcca tccacctcaa tattagtata
     6781 gctgatcaga ttttccggtt ttgtagaatc cacacaatga ggctgaaaat taatctcttt
     6841 agtctctttc ctcctaaaaa atatatcctg tgaacttcat cttctgcctg gctgtatccg
     6901 gcacatcgat cagcccaaag cggtagaaca ttccatatat ataactcact ccgcggatgt
     6961 cgcccagagc tttgggtctg tcaaccacag ctcccacctt ctttatgttt ctcaatgcca
     7021 gcagcactga acttaacgcc agactcttac tgttctccct acggtcgatc cacaattccc
     7081 ttgtgtagtc tccattccga ccctttctta cttcataagt gaacggaagc cctgtatagg
     7141 ttttgaaact ctcacctgca tagagtaaaa taacctccca cagatacttc tcgtccagtg
     7201 tttctctcag cttctctact gcctgatatc cttgtctttg ctgcattcct tccttttgat
     7261 ctcactccta ctcttttgat ttgcacttac aatttgtcag aacgctaaag cgcgtttgaa
     7321 aaatcatttc cataatctgc acgccccaat ttatctttct gattcggaca gatatattta
     7381 tactcatttc tgtttatact catttctgtt tatactcatt tctgagcaac gcaatttcat
     7441 gagtccatcc ctcatcgtca tttggtgtct ccagaataaa cggaattccc tctgtggcag
     7501 gatgattgat cacgcggaca agtgcctcca gtcctatttc accttctccg attctggcat
     7561 ggcggtcctt atggctgcca aggggattca tgctgtcatt taaatggatg gcttttagtc
     7621 tgtccagacc tattatccgg tcaaattctt caaatacgct gtcaagatcg tttacaatat
     7681 catatccacc atcccagaca tgacaggtat ccagacaaac acctaattta tcttttaact
     7741 ccaccctgtc aatgatctga cgaagttctt cgaaatttct tcctacttct gtgccctttc
     7801 ctgacatagt ttccagaagt acaatcgtac tctgatcttt tgtcagcact tcattgagaa
     7861 tttctgcaat tttactgatt cctacttctg caccctgtcc tacgtgactg cccggatgaa
     7921 aattgtaata atttcccggt gtcatttcca gacgtctcag atcatctgcc atgatttccc
     7981 tggcaaaatc cctgaggttt tctttggcag cgcagcagtt catagtgtaa ggcgcatgag
     8041 ccaccagctt tccaaaatga ttctcctctg ccagctgccc aaatgcctgc acatcctgcg
     8101 gatcaatgtc tttggctttc cctcctcttg gatttctggt aaaaaatgca aatgtgttac
     8161 cgccatttgc cagcatctgc ttccccattg caaggtagcc ccgggatgag cttgtgtgat
     8221 ttcctatata taacatcttt ttactcctct tctgtcgtat tttcacagta ccagtttata
     8281 gcaatccttt tatcatacat tatagatttt ttcaaaattt tctttttcat atctgcatta
     8341 tagcatttta acagattttg ttaaacattt ttactgttat aaacaacttt acgtcaaaaa
     8401 gacattgctg tgaacggagt caattgttcc aaaatttttc aggttgcgct tatgaactat
     8461 cttcatgtca atgaagacaa tatttcatct ggtcctgccc tttactttcc atgcaccaac
     8521 cttaacatcc tattccccaa caaacacccc agcatacatc ccaaactatt atgaataata
     8581 tcgtcaaact caaacaaccc tctgcaaagc agcagctgac taatctcgat agcagatgat
     8641 accgcaattc ccacaagcaa tcccatccac catttcagtt ttctgcctgt caaccccggc
     8701 aataaaatcc ctgccggaaa aagcagcaga atattcaaca gattctcctg cagtaagcca
     8761 tctcccgtag tacttcccag tctgccacat gtaccaatcc ccaggatttc cttccatgac
     8821 cagaatacct ccggctgata ctgcctgatc cccggagtcc tcgtaaaaac agtagaacca
     8881 aatacaattg caaaaaacgt cagaagcaac agtccacaga ctgcctgaat aatcactatt
     8941 ttatgcagcc ttaataatac tgctgccaga aaaacagcca tcaggaaaac cactgcaaaa
     9001 gcaataattt ccctgatcgt ccagcttcga ttatgtgtaa taataatctg ataaatgtcc
     9061 actatctatc tctccccatc ccatgaattc tgattttaac tgcctgtcaa tcggatattc
     9121 gcagtttatc agaaggagct tacaatcctc ctgatataag caagttccca cccactgctt
     9181 atcgcttttt gcaacctccg cagaggactt acctgattcg gttatatttt catttacaat
     9241 gaattatacc aaaactacct gattcttaca aagcactttt atcaatatcc ttcatataaa
     9301 tccccgggca tttcatggtg tctgaccaag agtattacgc agtacctgaa accagtagtt
     9361 gcggacacgg atcgtttctt tatgggcatc cgctacctcc gtctgcagtg cctggatctt
     9421 atgttcatag gctctgcact ccttttggtg gagttcgttc aacttaacat accgttcacc
     9481 ggattccagt tctttatttt tggtctgtgt ggctttcagc cgacatataa gtgagatgtg
     9541 atcatacgca tcaggcatat gttttcctcc agaacagtta taatcacata gaaaaaaagc
     9601 gaatcaccag aaagtgcctt ttcgtcaatc tgactgtgga taaatagctg ttttataata
     9661 aaaaaagtat tcatgcagac cttgaagctt caagaatggg ttcccaaaac tagaatctag
     9721 tgtataactt tttcacaaaa gttatacacc gaatcctatc cattctttca gacagaggcc
     9781 ttatatctgc tcatttccaa tcttataatg gagatttatc cacagtcaga ttgcccaatg
     9841 ggtcatttcc gggaattcgc ttttttcctg catttctgct atactttttt caagaaagag
     9901 aggttgtttt tatggagatt gattttatac aggaactaaa aaaacgtgat gaacttcttg
     9961 acggctatct caggcagatc gagatccagg aggaattcat ccagaaacag aaagagctga
    10021 tcgaatatct cgaggatcat atctcaaaga tcacagatat cgtcagcagt gtttagcagg
    10081 actgtaccgg aggaaaacgt atgcctgata cttatgatca tatcactctc atgtgtcggc
    10141 tgaaagctgc acaacgcaga aacaaagaac tggaatctgg tgaaagatat atccagttag
    10201 aagaacttta tcagaaagag tacaacgttt atgaacataa gattgagaag ctgaaaaaag
    10261 aacttgcaga tgcgcacaaa gaaacgatcc gtgtgcgcaa ttactggttt cagatactgg
    10321 aggatatgct ccgggagttt gaaaaggcac aaaaaaggtc cgcgcaggaa ctccgaaaaa
    10381 tggagatccg tgcactgaat gcagaaaagc aaagagatga tgcactggat aaagcagccg
    10441 ttttcagaca tcagttttat gaagcggcat ccagactgga agaagaacag ggaaagaatc
    10501 tgaaactacg ggcacagatc aaccgcgatt atgaaaactc ttctattcct tcttcaaaag
    10561 cagtacgacg caaaaagatc acaaacaaca gggaaaaaac aggcagaaga ccaggcgggc
    10621 agcccggcca caaagggcac tgccggaaaa gacaggagcc tacacagcca gttattcttc
    10681 ttcctccacc tgaagaagcg ctcgaagact gtgcttttaa aaagactgcc aggaccatcg
    10741 taaagcagat ggtaagtatc cgtatggtcc tgaatgtaac ggaatatcat gcagacgttt
    10801 attataacag tcatacggga gaacgtgcac atgcagcatt tccagacgga gttatcgatg
    10861 atgtgaatta tgatggcagc atacgggcat ttctgttcct tctgaacaat gactgctgta
    10921 catctattga taagagcaga gcatttctgt ccgacctgac gggtggaaaa ctgaatattt
    10981 ccaaaggcat gataagcaga ctaaaccggg agtttgcttt aaaaactgag cctgaacaca
    11041 ggtctgccta tgcagatatg ctgctttccc ctgttatgca tacggattgt acaaatgcca
    11101 gggaaaacgg aaagagctgc cagatatatg tctgcgcaac accggacgga aaagccctgt
    11161 actttgcccg tgagaaaaag ggacacgaag gagtaaaggg tacggttaca gaagactatc
    11221 aggggatcct tgtccatgac catgatatta ccttttataa ttatggagca gatcatcagg
    11281 aatgccttgc ccatgtactg cggtatctga aagccagcat agagaacgaa ccagaccgta
    11341 cctgaaataa aaaaatgcat gcactggtgc aggaaatggt ccacttccga aatggatgcc
    11401 ggcagccaca cggaccagat ccggaaatag tctccggatt cgaaaaacga taccgtgaga
    11461 tactggaaac tgcccggaaa gaatatgaaa acattccggc aaatgattat tataaagacg
    11521 ggtacaattt attcctgaga atggagaaat acatgcacaa ccatctgttg ttcctgcatg
    11581 atatccgggt acctgccacg aataatgaag ccgaaaggct tctaaggaat tataagcgga
    11641 aacaggcgca ggccgtgaca ttcagaagtt tcgaaagcat cgattatctc tgccaatgca
    11701 tgagcatgct tgttttgatg cgccttgaag atccggcaaa tatatatgac agagtgtcta
    11761 gaatatttgg ataaagaaaa ccgatgactt tgactgttat cagtgactgt tatcagtcta
    11821 caccatcgat tttctcaagt ccagctaacc cttgaacagt aacaggaaca gaaaaaagtg
    11881 cctcaaacat tgatgtaggt attacgcatg atccctacaa tatctccact gcatatattc
    11941 atcttcggaa atcattgtag cttttcataa cattataacg aaatgctgtg attctctctg
    12001 aattgtcagt gatgccatag caaaagagat cggtggtttc gacaagataa gcaatcttta
    12061 ttacgacggg aactggagcg aacactggta tgcccgtgtg actattggga accagacaaa
    12121 agattacacg ttttgtccgg atgtgagtac tggagacatt gaagaaatcc agaaaataaa
    12181 ttttatggac acttctaaaa tgacaaaaat atactaacca aacaaatggg cagaaacagc
    12241 tttaaaactg tttctgccct gcttttataa atctatgtta tccatttttg tattaccact
    12301 cttgcggtag attttcatat attttccgct tgtatccaga gtactccgat tccacctggc
    12361 ggtatatgtc tgctttactt ttaatttgac gtatcctttg tacaatttta atgttccagt
    12421 gccggaattg ccccatgtat ctttccactt aaaagaaact gtgtttcctt tacgctttgc
    12481 tgtaatggga gcagtcgcat agataggcga accattgact cccagttttt caagctgaag
    12541 cctgactttg gtactggtaa ccttatttac aatgacggaa tagctcggct tgatggtgac
    12601 cgtcatattg cttgaaacag accatgtttt tgtgtaggtc ccggtgtatt taccggaagc
    12661 tgcttgggct ggctggtaaa acgtaacagt aatcatgata gtcagcatta agaatagtaa
    12721 tctggaaaac ctttttctct tcatggtaat caaatcctcc tttatgttta taaacatatt
    12781 gtactactgg atttatatgg aaacaaggac gaaatacgga tttggaagtt ttaaaaacct
    12841 tgaccagggc gaatatgaaa tcacagaaat taagactaag cctgcagaag tacaggcatt
    12901 ttgctattat caaaccagtc acagaaccct gccatgtaca gcacagagga atccagtctg
    12961 gtaaagatac tcttttcttt cagggaattc cattcgtaga aaccgcctgc cggaatcaac
    13021 agccggtgat ataagatccc gttttgaaaa gaaggtttat ccaaaacagt ttctaccctt
    13081 gcattgatga ccagaccctt gctttttgac aggggatatc cccatctgca tatacccagt
    13141 tccagtccgt gttctgactg tccaatgact ggtgcgacat cggtcggacg ggtatctcct
    13201 tgtgccagcc agatcctccc atctatgttc tgtaccactc tggaaatatc ttccgtcata
    13261 ccgggatcaa tgtaatatct gctgcacata gttctctcct atttaagaat tcatgtactg
    13321 acagtacgtt agacttggat gattttcctt agggtactat attttgattt atctctgcag
    13381 tcagatccta cgtactgaaa aaaggagtcc aaatgactcc tttttctaat gcatatcaat
    13441 tatttttaaa atatcgtata tccgccatct acagccaaag ctgctccatg gatgaaacta
    13501 gcttcgtctg atgcaaggaa tgcaatggcc tgtgctactt cgataggttc tccaggacgt
    13561 tttgccggac tcattccaat cttcattgtt accggatgct gtggaattgc aagcacacgt
    13621 gcaatcatat ctgttgcaat cggtcctgga agaacagcat ttatacgcac tcctgtacgt
    13681 ccatgatcca atgacatctg acgggtgagt ccaagaaggc catgtttagc agaagtgtaa
    13741 gcaagccctc cgcggccagc tgcggttgct gccatggaag ctacattgac gatggttcca
    13801 gctccttgtt tttccataat agggattagt ttcttgcaaa gaacaaatgg tgctgtgaga
    13861 tttgttgcaa gaacagtgtt ccattcatcc attgtgatct gatccatatt ggcagttgtt
    13921 ccgcctactc ctgcattatt aacgagaatg tctatttttc cgtaggcgtc cagagctgtt
    13981 ttaaccaggt tatcaagact ttcatcagat gtcacgtctg ttttacagaa aattgcttct
    14041 cctccggctg ccttgattgc attcacacag ctttctccca gttcttcctt tgttccaaca
    14101 actatgactt ttgctccttc ttttgcaaag agttctgcgg ttgctcttcc gattcctctt
    14161 gttgaaccgg taatgattgc tactttgttt tcaaacttca tggcaatgcc ctccttatct
    14221 tcttcctgtt tccatgaatg ctgttctgtc ataccgtgcg gtaagcagat acggtgccag
    14281 aacatctgcg tcaatctctt cacataaatt cagtttatga accatcagat catttgagga
    14341 atacgcacct ccaatgactg ttctgattgg aagttctccc catggatcat caatggacga
    14401 ttgtaattta atcgctgcaa aaccaggctc ccatgaatgg taattgtatt cacagagatt
    14461 ctgaagcaga gcaccattct ggaaatgtga ttttccttct ttatccggtt cgcggtcaag
    14521 gtggaagtag aaaccaccgc catatgtctt tttaccggct tctgggaact gatacagcat
    14581 tccggtcatt gcgttattat attcaccaat cttgagatca atatttacaa gttcagtacc
    14641 acgacggcag acttgagcgg tcacatgatc attgtttcga cggattacaa attcagatcc
    14701 cagtttcttt ggaattgatc cattgtcacg tccacactga actgccattt ctgcaccggt
    14761 tcccccaagt acaagtccta ttggatataa tccaagctgt gttccatatg tacagtaaac
    14821 accaaggatt gcttcataat aatcatcagc aaaggtaggc tccttaacat ggcacacaga
    14881 taccgtaact acaggcacgg aaaatggttt taacggtgca ggcagaacct ttgcaatcgc
    14941 cgcaggatcg gtgaggtatg caagatatat tccctcctga tttttcataa gagatatctt
    15001 accgaaatta ggcatttcct ccggagcagt gataaagctt ggagttttga cagatgtctt
    15061 aaacaatttc cttgctgctt caaaaccact tctggatgca ggagcaatcg taccgtcttt
    15121 cacagcattt ccgatagcct gagcatggat tcctttttct tttaattctt caacaagatg
    15181 gttgtccgga cggaaaccaa gggaaagaac aacagcatct gcagcaactt ccacatttat
    15241 cttatcgttc agtctttcaa gtacaactcc atcttttttg atctctttaa gagcatatgc
    15301 catcatgaac tgggcattgt attctttcaa tcttccacat acatctgcaa catttgtatg
    15361 atttgcatta ggagcaactt tgtcaagcat atccgcaagt acaacggtat ttccttcgtg
    15421 acagagatat tctgctgttt caagtcccgt aacacctgct ccgatgatca ttactttttt
    15481 attcttcagt ccggcttttc cggaaagaat atcttcgatt gtatatacat tttctccggt
    15541 tattccggga atagatcctg gaatgacaga tttagaacct gttgctacaa gtaccgcgtc
    15601 cggattcatt tctgcaattt tatccgcagt cgcttccata tcaagtttta attcaactcc
    15661 aagtttctca aattcaacat tataataatc agcaatccag cccatacgtt ctttgaaagg
    15721 aggcttcttt gcaaggttta tcgtacctcc aagctcactc tggcggtcaa ccaatgttac
    15781 cttcatgccg cgttcagcaa gtgttttagc agcgatcata ccacatggtc cgccccccac
    15841 cactgcggcc ttctgttcct gagtgtcata ttctgcattt ccctcaagcc gttcgcggcc
    15901 tgcacgtgga ttaactgcac attccgccgg aatacccgcg cccatccatg cattcaggct
    15961 ctcaaagcag cgcagacaat tgatacattt acaaatttca ttctctcttc cttcaagtac
    16021 cttgagtccc cactgttcgt ctgcgagcca gcttcttccc atggagacaa aatcaacaat
    16081 acctccttcc agaaaactct cagctacctg tggttcacgt atgcaggaaa ctcctatcac
    16141 tggaatagaa acgtgatctt ttacggcctt gatcagatct tttctccaac cctgggggaa
    16201 ggagatcggc tctacacata cacttcctgt ctcgtataaa ccaacagaca catcaataaa
    16261 atcaatcccg catttctcaa gcgccattgc aatcttaact ccatcctgga tatggatata
    16321 atcctctgtc actcctgttt tatccagaaa ttcttcaacg cttaaacgga caccgatcgg
    16381 aaagtccggt ccacactgta cacggattcc atttatgatc tcggtgatca tacgaagtct
    16441 gttttcaaag gaaccaccat actcatcttc gcgtttattt gtgtaagggg aaagaaactg
    16501 ttgtaataga tacccatgag ccgcatgaag ctctactcca tcgcaacccg ctttttttac
    16561 ccgtacagca cctgagataa actgttggat caaagctttt acttcttctg ttgaaagagc
    16621 ccttgtttct tgctgaagat atttgcacgg tattgctgaa gcagatacta ccggaccgcc
    16681 tgtaagagca gttactgttt cacgtccagg gtgatgcagc tggatgaata tctttgtccc
    16741 atatttatgt actgtttctg caagctttgc aagaccttcg atatgtctgt cttttgaaac
    16801 agacagctga cgcatcatcc ctgcaccatg cagatcgttt acccttgcaa tctccggaat
    16861 aataagcgct gcgccaccaa ttgcacgtgc ctcatagaat gcaatcatgt cttccgatgg
    16921 agacccatcc atctccgcca ggcttgtacc catcggtgac attacaagcc ggtttttaag
    16981 tgtaatattt ccaatttttc cctgtttaaa tatttcctga tacatgtaca ccctccttta
    17041 cttgtgtctc ttgattatta tggcttaaaa ataacatttt cattgttaaa aaaacaacgg
    17101 cataaatata aaaaagacat tgtgtattta tgcacaatgc actataatta ataataatct
    17161 gcaaaacact gtgcattttt cacaaataat tgtaaagagg agtatgaaga tgctgttttc
    17221 cgatcttatt gattatttaa aaaatgaaaa aacttttaac ataatactaa attgttctac
    17281 tgatcttcat gaaatacgag atgtagagct gctggatggc actcaaacag gatacgccac
    17341 agatattgtc tattttggtt atccagatgt cttgtctcct gatatgcagc cttctcaatg
    17401 tatccttgtt cgtggagaaa actatctttt tccttattcc tgcacggatc gtgcaacagt
    17461 acaggcaaaa gagctttttg cggtttttaa tgcagcaaaa cagtttcttc agacacatga
    17521 acaggttagt ttatatgaag aactggttcg aaaaggccac tcttcccata gcctggatga
    17581 agtgattaac tctgcatcca tcaaattagg atattctttg gtattttgcg acaagaaatt
    17641 ccgtatcctg tcattttcta catcaattcc ggttacggat aagttatgga aagaaaatat
    17701 cgaacgtgga tattgtacat atgatttcat taaaaatgta atgtcattgg aagctgtcca
    17761 gggggcttca gccagcattg aagctgttga agtatcctgt ccggaatcac catatcgtaa
    17821 atgtagttcg aaagtgtttt taaacggtgt tcaggttggt tttgttctga tgatagaaaa
    17881 caatatccct tttaccgcag aacacttagc agctatgagt gatgtaagcc gggcgatcag
    17941 ctctgtagtt ggccattatc atcctgaact gtttcagtac accagtgcgg atcagcagct
    18001 tcttgaagct ctgctgatcg gaactccggc tgatatattg gcagaatcca tttctcatct
    18061 tcgagtatct gatgcaatgt atgcactttg tatccaaccg aagacatttt tgaaggaaaa
    18121 tgaattaaag cagcagcttt atcctgtgat ccggcatatc tttccggaag catatatgac
    18181 tgtccacgac aatgcattag tccttcttgt accagatcag agttctgtta tatttgtaga
    18241 tactcaaaaa gtaatgctca aaacgatggc agagtatcat ctggatgtcg gaatctccct
    18301 ggttttttca aaaatggatg aattttacag agcttatcag caggcacgga cagttcttga
    18361 atggaatcac agaatccctg ataaccttaa gaaggaaata tcatgggatc aaaggtatcc
    18421 gatggagcat caaattcatc ggtattctga aattgagttc tacgaaatga tgaacaagat
    18481 caaagaacca gaaaaacttg cagattatat ccaccctgcc ctttacagac tgaataaata
    18541 tgaccagaga acgggaaatg aactttacca tacacttgag gtatatctac agtgtttcca
    18601 taacaataag gaaacagcta acattttgtg tattcacagg aattcgctgg cttatcgaat
    18661 ggaaaaaatc attgaaatag gtaaagccga tttaaacgat cccatgacag agtttctgtt
    18721 gagaatgtct tttaagcttg tggaatattt gaagataaga gacctcgatc tcccctgata
    18781 tttaaaaagg aagcccggta taggcttcct tcagtttata tattacaaac cgtaaatgtc
    18841 tcaaaacatg gcgtagtgta aacgtgaact tcctgatttt gttttctacg ttcccttgtt
    18901 atttatgctg ctgacacacc attttcacct gtgcgtgtcc tgttttctac gccggaacgg
    18961 cggattcctg caaagatgga gcctgcaata ttatgccata cactgaaaat agcacctgga
    19021 agagttgcca gtggattggc tacaaagtta gctgctgcca gagaaactgc cagtccgctg
    19081 ttttgcatgc ccacttcaat agctatagct gttgcccgtg tatattctac atggaaaatt
    19141 tttgctgcaa ggagcccaag catcatacca cagaaattgt ggatcgcaac aacgccaagg
    19201 accagaactc cgcagcttaa gattttctct gcattaattg ccacgattcc gccaatgatc
    19261 ataacaatgg ctacaacaga gatcaatggc ataacatctg aaactttatc tacatgatct
    19321 cctgcaagtg tacggagaag gattccaaga agtacaggaa ccagaattac ttttacaaca
    19381 gaaagtacca ttgcccagaa ggatacttcc acccaggcac ctgccagaat gtacacaaga
    19441 aatggagtca taacaggagc agccagagtg gaaacgatgg tcattcctac tgaaagtgca
    19501 acatcaccgc ctgcaatata ggtgatcaca ttgctggctg ttccaccagg acagcatccc
    19561 acaagaatca cacccagagc cagatctgcg ggaagattca taactttaca caatacccag
    19621 gctacgactg gcatgatcgt atactgtgca actgcgccaa tgatcacttc ctttggtctg
    19681 gaaaaaattg cccggaagtc ttccagacgt atggtcagtc ccataccaaa catgatcacg
    19741 cccagaaaaa cagatgtata atttgtcatc catgcaaatc catccctcca gaaaaaggca
    19801 aggcatgaaa aggcaatgat gatgattcca atatatctgg atgcaaaact gctgattttt
    19861 cctattttct ttaaaatatt ttccaaataa tatacctcgt agctgaagtt atcgaccagt
    19921 cttgttttgc caatatagac agccattgct acgagaacat tatgatcagc tttttccaca
    19981 ggctgcatgg taagtgcatc taccatggaa acgtaatcga tttttgccag aggctctgcc
    20041 tcgatcactg cacgcatttt gccgagaagt tcttctgcgg aaatgcctgc gtgaatgatt
    20101 tcctgtccga gttttacgga tctggacaga cagagagcag cctttctctc ttcatcgctt
    20161 aaatatgtat ttctggagga ttttgccagt ccgtcctctt cacggacaat cgggcagcct
    20221 acgatttcta tatcaaaatt cagatcctgg accattttgc ggatgatggc cagctgctga
    20281 gcatccttct gtccgaaata tgctctgtcc ggggctacaa tatggaacag cttggttaca
    20341 actgtgcaca cacctttgaa atggatagga cgtgtttttc cacaaagtgt ctcagataat
    20401 gtatcgatac ttacaaatgc atggggatca tgatacattt cagaaggttc agggcagaag
    20461 atcaggtctg tgccaagact ttcacagagt ttgctgtcgc gttcgaaatc tcttggatat
    20521 gcctcaagat cctctgtcgg accaaactgt gttggattga caaagtcaga cacaactaca
    20581 atgtcgttct gttctctgca ttttttgatc agacttgcat gtccctcatg aagaaatccc
    20641 attgttggaa caagacctat agttttacct tcttttttcc atgctttgat ctgttttctt
    20701 gtttcttcta ctgtttttgt tacctgcatt gttatctcct ctttctcggt caatggaccg
    20761 gtatcataga ttttgagata gcctcttttc tgaattcact ttcatcttat gatagcctct
    20821 aatctgatat caacgttttc aggccatgtc tttcagcaga ccatgtttct cataattggt
    20881 cactctgctg atcttattct cttcatctac aaatacaaca gcaggcttat gaatgcgtgc
    20941 ctcttcaggc tcatatcctg cgtaagccat gatgataatc ttgtcacctg tgcttacaca
    21001 tcttgctgct gctccgttca gacagatcat accgcttccg cgttttccgc agattgtgta
    21061 tgtctcgaat cgactgccat tgttcacatc tacaatctga actttctcat attccagtat
    21121 tccggcagct tccagcagtt cttcatccac agtaatgctt cccacataat ccagttcagc
    21181 ctggataaca gttgctctgt ggatttttcc ttttaacatt tctattgtca tcttatatag
    21241 tcctttcctg cgggaaaaat cagagtcaag cagcaccata aaaaggaaat atacctttat
    21301 gatctgcaaa aaaagcgcat caggatacac tttgaccctg aaacgcttct gattgattcc
    21361 ctgtatattg agtcctgttt ctgatacata aaatatgttt tactattcca tagattattg
    21421 gaaatctgat tttttgtatc ataaataccg gctcgtatct tttaaaatta catacatccc
    21481 tccgttcccg tttccggatt ccggctggct gcttttatat aagattccag tgatttcagc
    21541 cagagtatag ttttgagtcc aaatactatc tctgagtggt attattacat ctggtcagtt
    21601 atttgtcaat aaattgttta tttactggtt actgttcact ccgcgtccag taatacactg
    21661 cgaaatacaa taaatatgaa tctccttgtg caaagccaaa ggagtatcgt ttgcttcgca
    21721 gacgtaattt atgctaatca catatggaac caaaaaatca ctcatctgac aaacaatcag
    21781 acggatagcc tcatccaacc gtaccttccc gggagttatt tccaattcgt tcatatgtgc
    21841 aaagaaattt ttccgaaaga cttcatacgg catcaataac tctgcagcaa acaggtttgt
    21901 aatctgaatg tcagaaacta aacagctatt accataaaaa taaaaagttt ctctttatga
    21961 tacagctctc cgaac
//
