LOCUS       gnlProkkaCJENKGDL_48    3675 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CJENKGDL_48.
ACCESSION   gnlProkkaCJENKGDL_48
VERSION     gnlProkkaCJENKGDL_48
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 22:38:37
            Original ID  :: gnl|Prokka|CJENKGDL_48
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3675
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3675
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2:3674]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..3674
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..3675
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3675
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             complement(3..3674)
                     /NRPS_PKS="Domain: PCP (365-434). E-value: 9.8e-23. Score:
                     72.1. Matches aSDomain: nrpspksdomains_ctg48_1_PCP.1"
                     /NRPS_PKS="Domain: Heterocyclization (451-748). E-value:
                     5.3e-103. Score: 336.3. Matches aSDomain:
                     nrpspksdomains_ctg48_1_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (911-1209). E-value:
                     2.1e-69. Score: 225.9. Matches aSDomain:
                     nrpspksdomains_ctg48_1_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transferase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     124; E-value: 1.6e-37)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_1"
                     /sec_met_domain="PP-binding (E-value: 6e-18, bitscore:
                     51.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.7e-52, bitscore:
                     163.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="Transferase (E-value: 3.6e-11, bitscore:
                     28.4, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.2e-69, bitscore:
                     219.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQKEIFEKGSITETQKNTVARWLEILKKEGILREEDGRLSRTGK
                     EVAVPEKAGDAETYFKKLKPYLKHMVTGNEVPLDVFYQKEPALAPNMLLRRIPGCEETV
                     ERLVQGLRLLTEERRKEPLQIIEIGTRDTATTRQFLNALEDVSVAYTYADSSKYFLQEA
                     EKELAGYERVEFEMLNLEEGMDKQQMSSHSYDVVISVNALHRNIDAADAVKKVAELLKP
                     NGILLMTDLVVRTYLQELTAAFLENGFADIRDKRKEAGLVTPDCLLWRECLSEAGLGED
                     CAVTERYGRCICCSRQQASVLSYHNGALREYLSEKLPEYMVPQNYHFMEQLPTLSNGKI
                     NRKQLREDFKEETAVIRFSKATTETEEKLLDIWKQLFGYENIGIEDNYFSLGGDSLIAT
                     RLISEVQKTFGCKITISTIFENLTVKSLAKTIEQSEQKEEDTLQIKPNLEEAYHPFPLT
                     DVQYAYWLGRSGLYELGNVATHCYFELDADGLDTECAETAWNLLIQRHGMMRVIIQPDG
                     MQRILENTPQYHIDVTDIRQLEVTEKEKALDEKRAEMSHQVIQTDEWPLFDVRITIIED
                     QKHRIHISFDNIIFDGWSMFHLLNEWAEVYRNGKAEMPITLSFRDYVLGLEQIKSTSAY
                     EKDKKYWEDRVETFADAPDLPLAKNESQITEQRFCRRSAKLSQKEWQSVKDAAGRLEVT
                     PSVLLMSAYAETLRLWSSNKDFTLNLTQFDRKQLHPEVNNLVGDFTTLTLLEIKNAGNN
                     FAERTKAIQKQLTEDLEHTAYGAVELERELKKKTGNMRGAIMPVVFTSGLGVEQWNEGK
                     WLGKLNYNISQTPQVWLDHQVVEMDGCLCLFWDSVDELFYPGMLDEMFRAYTGLLHTLA
                     VHPEIMQEKTASLVTAEISEKRRQANETAAEFEEKTLDGLFLESADKFPDKEALVTCSR
                     RMTYREIKEEAFYISGQLQSMGIKKEETVAVFMEKGWEQVVAVYGILFAGAAYLPIDIH
                     NPRERVEKILRDSGTRIILVQNQAYDQDTEWLHEWDCISVSGLKTDSEYKAQENKAGDL
                     AYVIYTSGTTGMPKGVMITHHNAVNTILDINARYQITEQDTAFGISNLHFDLSVYDVFG
                     ILGAGGKLVLPDPEYGKDPAHWIHWLNHENITVWNSVPAFVEMLAEYEEYQRQVTSQSL
                     RLVMMSGDWVPVSLPGRIRNLFQNVEIVALGGATEGSIWSNHFEIPEVVPEDWKSIPY"
     aSDomain        complement(48..941)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg48_1_AMP-binding.1"
                     /evalue="2.10E-69"
                     /label="ctg48_1_AMP-binding.1"
                     /locus_tag="ctg48_1"
                     /protein_end="1209"
                     /protein_start="911"
                     /score="225.9"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="FLESADKFPDKEALVTCSRRMTYREIKEEAFYISGQLQSMGIKKE
                     ETVAVFMEKGWEQVVAVYGILFAGAAYLPIDIHNPRERVEKILRDSGTRIILVQNQAYD
                     QDTEWLHEWDCISVSGLKTDSEYKAQENKAGDLAYVIYTSGTTGMPKGVMITHHNAVNT
                     ILDINARYQITEQDTAFGISNLHFDLSVYDVFGILGAGGKLVLPDPEYGKDPAHWIHWL
                     NHENITVWNSVPAFVEMLAEYEEYQRQVTSQSLRLVMMSGDWVPVSLPGRIRNLFQNVE
                     IVALGGATEGSIWSNHF"
     aSModule        complement(48..2321)
                     /domains="nrpspksdomains_ctg48_1_Heterocyclization.1"
                     /domains="nrpspksdomains_ctg48_1_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg48_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(471..530)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg48_1_0010"
                     /evalue="1.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg48_1"
                     /protein_end="1068"
                     /protein_start="1048"
                     /score="33.0"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGMPKGVMITH"
     CDS_motif       complement(714..752)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg48_1_0009"
                     /evalue="1.20E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg48_1"
                     /protein_end="987"
                     /protein_start="974"
                     /score="12.4"
                     /tool="antismash"
                     /translation="GILFAGAAYLPID"
     CDS_motif       complement(1170..1214)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg48_1_0008"
                     /evalue="1.50E-07"
                     /label="Cy7"
                     /locus_tag="ctg48_1"
                     /protein_end="835"
                     /protein_start="820"
                     /score="24.2"
                     /tool="antismash"
                     /translation="ISQTPQVWLDHQVVE"
     CDS_motif       complement(1263..1292)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg48_1_0007"
                     /evalue="2.40E-03"
                     /label="Cy6"
                     /locus_tag="ctg48_1"
                     /protein_end="804"
                     /protein_start="794"
                     /score="10.6"
                     /tool="antismash"
                     /translation="MPVVFTSGLG"
     CDS_motif       complement(1326..1373)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg48_1_0006"
                     /evalue="2.10E-03"
                     /label="afterCy5"
                     /locus_tag="ctg48_1"
                     /protein_end="783"
                     /protein_start="767"
                     /score="11.1"
                     /tool="antismash"
                     /translation="DLEHTAYGAVELEREL"
     aSDomain        complement(1431..2321)
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg48_1_Heterocyclization.1"
                     /evalue="5.30E-103"
                     /label="ctg48_1_Heterocyclization.1"
                     /locus_tag="ctg48_1"
                     /protein_end="748"
                     /protein_start="451"
                     /score="336.3"
                     /tool="antismash"
                     /translation="YHPFPLTDVQYAYWLGRSGLYELGNVATHCYFELDADGLDTECAE
                     TAWNLLIQRHGMMRVIIQPDGMQRILENTPQYHIDVTDIRQLEVTEKEKALDEKRAEMS
                     HQVIQTDEWPLFDVRITIIEDQKHRIHISFDNIIFDGWSMFHLLNEWAEVYRNGKAEMP
                     ITLSFRDYVLGLEQIKSTSAYEKDKKYWEDRVETFADAPDLPLAKNESQITEQRFCRRS
                     AKLSQKEWQSVKDAAGRLEVTPSVLLMSAYAETLRLWSSNKDFTLNLTQFDRKQLHPEV
                     NNLVGDFTTLTLLEIK"
     CDS_motif       complement(1434..1490)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg48_1_0005"
                     /evalue="3.00E-09"
                     /label="Cy5"
                     /locus_tag="ctg48_1"
                     /protein_end="747"
                     /protein_start="728"
                     /score="28.9"
                     /tool="antismash"
                     /translation="HPEVNNLVGDFTTLTLLEI"
     CDS_motif       complement(1491..1529)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg48_1_0004"
                     /evalue="1.20E-03"
                     /label="afterCy4"
                     /locus_tag="ctg48_1"
                     /protein_end="728"
                     /protein_start="715"
                     /score="11.6"
                     /tool="antismash"
                     /translation="FTLNLTQFDRKQL"
     CDS_motif       complement(1542..1598)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg48_1_0003"
                     /evalue="1.40E-07"
                     /label="Cy4"
                     /locus_tag="ctg48_1"
                     /protein_end="711"
                     /protein_start="692"
                     /score="24.2"
                     /tool="antismash"
                     /translation="VTPSVLLMSAYAETLRLWS"
     CDS_motif       complement(1893..1937)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg48_1_0002"
                     /evalue="1.70E-05"
                     /label="Cy3"
                     /locus_tag="ctg48_1"
                     /protein_end="594"
                     /protein_start="579"
                     /score="17.9"
                     /tool="antismash"
                     /translation="RIHISFDNIIFDGWS"
     CDS_motif       complement(2118..2171)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg48_1_0001"
                     /evalue="1.90E-07"
                     /label="Cy2"
                     /locus_tag="ctg48_1"
                     /protein_end="519"
                     /protein_start="501"
                     /score="23.4"
                     /tool="antismash"
                     /translation="LIQRHGMMRVIIQPDGMQ"
     aSDomain        complement(2373..2579)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg48_1_PCP.1"
                     /evalue="9.80E-23"
                     /label="ctg48_1_PCP.1"
                     /locus_tag="ctg48_1"
                     /protein_end="434"
                     /protein_start="365"
                     /score="72.1"
                     /tool="antismash"
                     /translation="EEKLLDIWKQLFGYENIGIEDNYFSLGGDSLIATRLISEVQKTFG
                     CKITISTIFENLTVKSLAKTIEQS"
ORIGIN
        1 ccatacggaa tactcttcca atcttccggc acaacctctg gaatctcgaa atgattagac
       61 cagatactgc cttctgttgc tcctccaaga gcaacaatct caacattctg gaacagatta
      121 cggattctcc ctggaagtga aacaggaacc cagtcaccac tcatcattac taaccgcagc
      181 gattgtgaag ttacctgcct ttgatattcc tcatattctg ccagcatttc tacaaaagct
      241 ggcacgctgt tccatacggt aatattctca tgattcaacc agtgaatcca atgcgctgga
      301 tcttttccat attccggatc cggaagaacc aatttcccac ctgcgcctaa aatgccaaaa
      361 acatcataaa cagacaggtc aaaatgaaga ttggagattc caaacgccgt atcctgttct
      421 gtaatctgat agcgtgcatt gatatccagt atcgtattca ctgcattatg gtgagtaatc
      481 attactcctt tcggcatccc ggttgttccc gacgtataga ttacatacgc aaggtctccc
      541 gccttattct cctgtgcttt gtattcagaa tcggttttta atccagacac agaaatacaa
      601 tcccactcgt gcagccattc ggtatcctga tcatacgcct gattctgcac aagaatgatt
      661 cttgttccac tatcacggag aatcttttca actcgttctc tcggattatg gatatctatc
      721 ggaagatatg cggctccggc aaacaggatt ccataaacag caactacctg ctcccaccct
      781 ttttccataa atacagctac cgtctcttct ttttttattc ccatgctctg caactgcccg
      841 gaaatgtaaa acgcttcttc ttttatctcc cgatatgtca tccgcctgct gcacgttacc
      901 agcgcctcct tatccggaaa tttgtctgcc gactccaaga ataatccatc caacgttttc
      961 tcttcaaatt cagccgccgt ttcattcgcc tgacgccgtt tttctgaaat ttccgctgtt
     1021 accagacttg ccgttttttc ctgcatgatc tccggatgaa ctgctagcgt atgaagcagg
     1081 ccggtatatg cccggaacat ctcatccagc attcccggat aaaataactc gtccacggaa
     1141 tcccaaaaca ggcataaaca gccatccatt tcaaccacct gatgatccaa ccacacctgc
     1201 ggcgtctgtg aaatgttata gttcagtttt ccaagccact ttccttcatt ccactgctcc
     1261 acgccaaggc cactggtaaa cactaccggc ataatagcgc cccgcatatt tccagtcttt
     1321 ttctttaatt cgcgctccag ttcaaccgcg ccataagctg tatgctccag atcttctgta
     1381 agctgcttct gaattgcctt tgtcctttcc gcaaaattat tccctgcatt ctttatctcc
     1441 agcaatgtca gtgttgtaaa atctccaacc agattgttca cttccggatg caattgtttc
     1501 cggtcaaact gcgtcagatt aagtgtaaaa tccttattac tgctccacaa acggagagtc
     1561 tccgcataag cactcatcaa aagaacagaa ggcgttacct ccagtcttcc cgccgcgtct
     1621 tttacagact gccattcttt ctgtgacagt tttgcgctcc ggcgacagaa acgctgctct
     1681 gtaatctggc tttcgttctt tgcaagtggc agatccggtg cgtccgcaaa agtctccacc
     1741 cggtcttccc aatatttttt atctttctca taagcagagg tagactttat ctgctccagt
     1801 cccagcacgt aatcccggaa agacaaagta atcggcattt ccgcttttcc atttcgatat
     1861 acttctgccc actcatttaa gagatggaac atactccagc catcaaagat aatattgtca
     1921 aaactgatat ggattctatg cttctggtcc tctattatag tgattcgcac atcaaacaga
     1981 ggccattcat ctgtctgaat tacctgatga gacatctctg cccgtttttc atccaatgcc
     2041 ttttcttttt ctgtcacttc caattgtcgg atatccgtca cgtcaatatg atactgggga
     2101 gtattctcca gtatgcgctg cataccatcc ggctggataa taacacgcat catcccatgc
     2161 ctctgtatca acagattcca tgccgtctct gcgcactcag tatcaaggcc gtctgcatcc
     2221 agttcaaaat aacagtgcgt tgcaacattt cccaattcat acaatccgct tctgccaagc
     2281 cagtaagcat actgcacatc ggttaatggg aacggatgat atgcttcctc cagattcggt
     2341 ttgatctgca gtgtatcttc ttctttctgt tcggactgtt caatagtttt tgccagagat
     2401 tttacggtca gattttcaaa aatcgtactg atcgttattt tacagccgaa ggttttctgt
     2461 acttccgaga tcaaccttgt ggcaatcagc gagtctcccc caaggctaaa ataattatct
     2521 tcaattccga tattttcata tccaaataat tgtttccaga tatctaaaag cttttcttct
     2581 gtttctgtcg ttgcctttga aaatcggata accgcagttt cttctttaaa atcttcccgc
     2641 aattgcttcc tgttaatctt cccattggac aatgttggga gctgctccat gaaatgatag
     2701 ttctgtggaa ccatatactc cggcagtttt tctgatagat attcccttag tgctccatta
     2761 tgataggaca ggacagacgc ctgctgtctg ctgcagcata tacatcttcc atatctctct
     2821 gtcacagcac agtcttcgcc caatcctgcc tctgataaac attctctcca cagcaggcaa
     2881 tccggggtaa ccagccctgc ttcttttctc ttgtcccgaa tatccgcaaa accattttcc
     2941 aaaaaagccg ctgtaagttc ctgaaggtat gtccttacca caaggtcagt catcagcaat
     3001 attccgtttg gcttcagtaa ttccgctact ttctttaccg catccgcagc atcaatattt
     3061 ctatgtaaag catttaccga tatcacaacg tcataactat gcgaggacat ctgctgctta
     3121 tccatgcctt cttccagatt cagcatctca aactcaactc tctcatatcc tgcaagttct
     3181 ttctctgctt cctgcagaaa atattttgaa gaatccgcat atgtataagc cacgcttaca
     3241 tcttccagtg cattcaaaaa ctgtcttgta gttgcagtgt cccttgtacc aatttctata
     3301 atctggagtg gctcttttct gcgttcttct gtcagaagcc ttaatccctg caccagtctt
     3361 tccactgttt cctcgcagcc cggaatcctc cgaagcaaca tattcggagc caaagccggc
     3421 tctttctggt agaatacgtc cagcggaact tcattcccag taaccatatg cttcagatac
     3481 ggcttcagtt tcttaaaata cgtttccgca tctccagctt tttccggtac agccacttcc
     3541 ttcccggtac gcgatagtct gccgtcctct tctctcagga ttccttcctt ctttaaaatt
     3601 tccaaccatc ttgccacagt attcttctgt gtttccgtaa tgctcccttt ttcaaaaatt
     3661 tccttctgcg aaaga
//
