LOCUS       c00025_gnlPro..        11273 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CJENKGDL_25.
ACCESSION   c00025_gnlPro..
VERSION     c00025_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 01:28:34
            Original ID  :: gnl|Prokka|CJENKGDL_25
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11273
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1080)
                     /locus_tag="ctg25_1"
                     /transl_table=11
                     /translation="MKRNKHHGLNVEFDGLCMDFGHVSLNKKKEFLCGDCYKIEENDED
                     HVLVLSDGLGSGVKANILSTLTATMLSTMIINQVELDEAVRAVAKTLPVCSVRNLAYAT
                     FTVLNFQGKQVSLYQFDNPDAILIRDGKLFDYPVETSMIEEKEIHKSCFELKDEDMLII
                     MSDGVTNAGMGKTTNGGWGRDDVMAFCRAKYHKGMSAQEMAGYLAEASLDLNLNETDDD
                     ITAIVLRMRHKQVVNLMIGPPSKEEHDERYLKSFFDSEGYHVICGGTTAQCAARYLDKE
                     LISLSETACGDVPAYYKLEGTELVTEGFLTIEHLLEYCEEWMEDRLSFNRLKRKKDAAA
                     LLGVMLFEQATDINFYFGGA"
     protocluster    1..11273
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1066:7601]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1067..7601
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..11273
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11273
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(1067..2791)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_2"
                     /sec_met_domain="Fer4_7 (E-value: 1.9e-09, bitscore: 27.2,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.9e-08, bitscore: 23.1,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 4.3e-12, bitscore: 34.8,
                     seeds: 364, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQRFQSILQFKKVSCKNCYKCVRNCPVKAIRVHDHQARIIESQCI
                     YCEKCILVCPQDAKEEQNMIPAICNAMENKTQVIASLHPAYLARFGVTGINGIREAMKK
                     LGFADAADAAEGASLMISQYRALFAEQKEPGIMISSACPVIVQLVKKHYPHLLGNLVQS
                     ASMMQFHASYLKKKYPKAEIVYVSPCISAMSELRDSGNEVDYVITLEEMVQWMKKEGIS
                     ITEKEPEQIAYRSREIAIADGLTDLLGDVKGIRRLSVSGMEQCREVLEELHPEDFENCF
                     LEMYACSGGCVAGPSFQMKKGHYLADVLAVKNAAFGKDFHREQGDYELPGFELRKNFGY
                     CSAQEQEEVSEEEIRDALAEMGKFSPKDELNCGACGYNTCREKAIAIIQNKAEVAMCIP
                     YMRAKQESYSNKVFNAMPGLLVTVDYNLKIIQMNEAASKLFNMPKKRRLIGKQVSEIMD
                     DYSLASILAFERNLMQDEIYLEDQKCYLDRVMTNDKENKMILCIMKDITKERKHKDQIH
                     NAQIEAARMADKLVEEQLKIVQQIAGLLGETAADTKVAVEKLKNTILLESEEENEKK"
     CDS             complement(3002..5710)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Molybdop_Fe4S4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Molybdopterin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Molydop_binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH-G_4Fe-4S_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_3"
                     /sec_met_domain="Fer4 (E-value: 2.1e-10, bitscore: 29.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2 (E-value: 2.3e-12, bitscore: 36.0,
                     seeds: 206, tool: rule-based-clusters)"
                     /sec_met_domain="Molybdop_Fe4S4 (E-value: 2.5e-13,
                     bitscore: 39.1, seeds: 55, tool: rule-based-clusters)"
                     /sec_met_domain="Molybdopterin (E-value: 1.3e-96, bitscore:
                     313.2, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 6.9e-31,
                     bitscore: 95.8, seeds: 74, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_4 (E-value: 1.2e-18, bitscore: 56.2,
                     seeds: 126, tool: rule-based-clusters)"
                     /sec_met_domain="NADH-G_4Fe-4S_3 (E-value: 3.5e-19,
                     bitscore: 57.3, seeds: 418, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHLTIDGIPVEVEKGTTILQAARQIGVEIPTLCYLEDVLPDGSC
                     RLCVVEVTNNGRTKFDTACTLRCSEGDEVQTMSEKVVAYRKDTLDLLLSDHRVHCFSCE
                     ANGDCKLQDYCFEYGVTETSYPGEMKDMPIDDTNKFFTYDPSLCILCHRCVNTCKEIVG
                     RGAIDTMDRGFQSVIGAHYKHKWNEGICESCGNCVQACPTGALTMKRRKKYRPYQIDKK
                     VLTTCPHCATGCQYYLLVKDGKIVDTEAVNGPSNKGLLCVKGRSGCFDFVQSPERIKYP
                     LIKNKETGEFERATWDEALDLVASKFMEIKKQYGSDSLAGFACSRSPNEDIYMVQKMVR
                     CCFGTNNTDNCARVCHSASVSGLAMTLGSGAMTNPIEDITKNADLIMLVGSNPEEAHPV
                     VGMQIRQAIKRGCKLIVVDPRDIGLAKKADIHLKLKPGTNVAFANGIMNVILSEGLQDD
                     KFIAERTEGFEELKEIVKDYTPEKVAEICHIDADDLRKAAIMYAKADRAPIIYCLGVTE
                     HSTGTEGVMSMSNMAMMVGKLGREGCGVNPLRGQNNVQGACDMGAQPNVYPGYQKVTDP
                     AVREKFEKAWGVKLDPNIGTHATDVFPKAITGEIKGLYIYGEDPVVTDPDTTHIIKALK
                     SLDFFVLQELFMTETAQYADVILPGVSYAEKEGTFTNTERRVQRVRKAVTVPGEMRLDT
                     DIIIDLMNRMGYPQPYLTSAQIMDEIASLTPSFAGISHERLDSEEVHGQGLQWPCTSKD
                     HPGTPIMHVGKFSRGLGWFYPAKYVPSAELPDEEYPIILMTGRILYHYTTRAMTGKTPE
                     LMEIEGKSFIEMNIVDADKLGIKNGDKVRVSSRRGSIESTARVGTKTSPGESWMPFHFP
                     DGNANWLTNAALDKYARIPEYKVCAIKIEKA"
     CDS             complement(5724..7601)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH_4Fe-4S"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_4"
                     /sec_met_domain="Fer4 (E-value: 1.2e-10, bitscore: 30.1,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1.6e-11, bitscore: 33.1,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.3e-48, bitscore:
                     153.1, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 1e-10, bitscore:
                     30.8, seeds: 130, tool: rule-based-clusters)"
                     /sec_met_domain="NADH_4Fe-4S (E-value: 3.6e-37, bitscore:
                     115.4, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQNKEVLEQIREEAVKELNSYDCRILVCSGTGCVATGSQKIYEK
                     FMEIAKDAPGVTIEFGPHDKDAHVGVKKTGCQGVCELGPLVRIQKGDDVIQYTKVQIED
                     CQEIFEKSVQGNETIERLLYQKGGKVSRGPEDIPFIAKQTRIVLKNCGKFDAESLNEYI
                     ASGGFQALEKAMFEMDPDLVIDQVDKSGIRGRGGGGFPAGKKWIQVARQADPVHYVVCN
                     GDEGDPGAFMDGSVMEGDPYRLIEGMMLAAYAVRAQHGYIYVRAEYPQSVARLKHAIAV
                     LEEVGLLGDDILGTGFSFHMHINRGAGAFVCGEGSALTASIEGSRGMPRVKPPRTVEQG
                     LWAKPTVLNNVETYANIPEIILKGADWYRSIGTEGSPGTKTFSLTGSIENTGLIEVPMG
                     TTLREIIFDIGGGLKSGAAFKAVQIGGPSGGCLTEEHLDVPLDFDSVKKYGAIVGSGGL
                     VVMDEHTCMVEVARFFMGFTQRESCGKCGPCRIGTKRMLEILERIVDGKGEVEDLDKLE
                     HLGNFIKDRSLCGLGKSAPLPVLSTLRNFRDEYVEHIVDKKCAAHVCKAMRSYVIDPEK
                     CKGCTKCARNCPVGAITGNKKEPHSIDTSKCIKCGTCLENCVFGAISVN"
     CDS             complement(7598..8080)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_5"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 6.4e-52,
                     bitscore: 164.4, seeds: 130, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDQSFYQKADEIIAFYGKKPASLIPIMQDIQGVYRYLPEELLTY
                     VAEQIGVTEAKAFSVATFYENFSFDAKGKYVIKVCDGTACHVRKSIPVLEELYKKLGLS
                     KTKKTTDDMMFTVETVSCLGACGLAPTMMVNEEVYPRMTPEKADELIDKLRGGEQG"
     CDS             8557..9675
                     /locus_tag="ctg25_6"
                     /transl_table=11
                     /translation="MFSLKEKEVNTGRQRELDLVKGFLLIMIVFIHSFQTIGGVAAAES
                     NVHKILFALFMPTGACLYLFTMGFGSAFTRHSQPKDMVKNGIKLLFYQGLSNLCYAAVM
                     TISFNIRNSITVEAAGSRELYDANLYSMLTFVNIFFIAGMCYLVLAVYRKLNVSLRGYV
                     ISAVIVGIISPFTKLLVSDDPALNWILDMTFGGKGETSFCFFPYLSYVFLGYVFGKVLR
                     RIPEDEKGNFYKESGIICGITAAVWFICCIVLHPGIEGFFNYMIEQYRIPGLAKVLGSF
                     CSIIFVFAAAFRIMPMMEKWKFGYNKLCYYSKQISKMYAVHIGVYWTLAGFAAFYEFGV
                     KECLILSVAALIVTDLLVHGYIIITDKIKNRK"
     CDS             complement(9765..10457)
                     /locus_tag="ctg25_7"
                     /transl_table=11
                     /translation="MSRKVLVVDDEKLIVKGIRFSLEQDGMEVDCAYDGEEAVEKAKDK
                     KYDIILLDLMLPKMDGLEVCQQIREFSNVPIVMLTAKGEDMDKILGLEYGADDYITKPF
                     NILEVKARIKAIMRRAGSDHEEKEKAKSIQVGDLRMDCEGRRVFIAGKEINLTAKEFDV
                     LELLVFNPNKVYSRENLLNIVWGYEYPGDVRTVDVHIRRLREKIETNPSEPKYVHTKWG
                     VGYYFQAQ"
     CDS             complement(10468..11271)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_8"
                     /sec_met_domain="SLBB (E-value: 5.6e-13, bitscore: 37.8,
                     seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="YTVTRLLCGTLFLTGLTGCKSREAQFLIDGLQEAKAEVDAESSEE
                     KTSGQKSKKDTDEKKADTEDRQNDDGSSAESRKKQAESGGSDAGNGMEINSTGETQPEM
                     IYVDVCGAVANPGVFQLATGSRVFQAIEAAGGYLPEAVQNCVNRAGVLTDGQQLYILPQ
                     EERERQGLDPAEMAGASDGQMNGSAGTGQNTGMTAQVQQDNRININTADEAQLTTLTGI
                     GATRAQAIIAYREENGPFAAIEDIMNVQGIKEGTFAKIKDEIVVG"
ORIGIN
        1 agcaccaccg aagtagaaat taatatccgt tgcctgctca aacagcatca caccaagcaa
       61 tgctgccgca tctttttttc gtttcagcct gttaaaggac agcctgtcct ccatccattc
      121 ttcacaatat tcaagcaaat gctcaatcgt aagaaatccc tctgtcacca gctctgtacc
      181 ttccagctta taataggcag gaacgtctcc gcaggcagtt tcactaagag agatcagctc
      241 tttatccaga tatctggcag cacactgtgc agtagttccg ccgcagatta catgatatcc
      301 ctctgaatcg aaaaaggact tcagatatcg ctcatcatgc tcctccttac ttggcgggcc
      361 gatcataagg tttaccacct gtttatgccg catccgcagg acaatggctg taatatcatc
      421 atccgtttca ttcagattca gatccaggct ggcctctgcc agatagcctg ccatctcctg
      481 tgcgctcatc cctttatggt actttgccct gcagaaagcc attacatcat ctcttcccca
      541 gccgccgttg gtagtttttc ccattcccgc attggtgaca ccgtcggaca taatgatcag
      601 catatcctca tctttcagtt caaaacagct tttatggatt tccttctctt cgatcatact
      661 tgtctccacc ggataatcaa agagcttgcc atcccgaatc agaattgcat ccggattatc
      721 aaactgataa aggcttacct gtttcccctg aaaattcagt actgtaaaag tggcatatgc
      781 cagatttctc acactgcaca caggaagcgt ttttgccact gcacgcactg cctcatccag
      841 ttccacctga ttaatgatca tggtactgag catggtcgca gtcagcgtgg aaaggatatt
      901 cgcctttact ccgctcccaa gtccgtcaga aagcaccaga acatggtctt catcattttc
      961 ttcaatctta tagcagtccc cacagagaaa ttctttcttt ttattcaggc tcacatgacc
     1021 aaaatccatg cataagccgt caaattccac attcagtcca tgatgcttat ttcttttcat
     1081 tctcttcttc actctccaga agtatggtat ttttcagttt ttctactgcc actttggtgt
     1141 ccgcagcagt ttctccaaga agtccggcga tctgctgcac gatcttcagc tgttcttcta
     1201 ccagcttatc tgccatacgc gcagcttcaa tctgggcatt atgaatctga tctttatgct
     1261 tccgctcctt tgtaatatcc ttcataatgc agagaatcat tttattttct ttatcattcg
     1321 tcattacgcg atccagataa catttctgat cctccagata aatctcatcc tgcatcagat
     1381 tccgttcaaa agccagtata ctcgccagac tgtaatcatc catgatctcc gatacctgtt
     1441 tcccgatcag gcgccgcttt ttcggcatat tgaacaattt ggacgccgcc tcattcatct
     1501 gaatgatctt cagattataa tccacagtta ccagaagtcc gggcatggca ttaaagactt
     1561 tattggagta actttcctgt tttgcccgca tatatggaat gcacatggca acctcagctt
     1621 tattctggat aatggcaatt gccttttccc tgcatgtgtt gtacccgcag gcaccgcagt
     1681 ttaattcatc ctttggagaa aattttccca tttccgccag agcatccctg atttcttcct
     1741 ctgagacctc ttcctgttcc tgtgcagaac agtaaccgaa attctttctc agctcaaatc
     1801 ccggaagttc atagtctccc tgctctctgt gaaaatcttt tccaaaggct gcattcttca
     1861 ctgccagaac atctgccaga taatgtccct tcttcatctg gaaagaagga cctgccacac
     1921 agccgccgct gcatgcatac atctcaagaa agcaattttc aaaatcctcc ggatgaagtt
     1981 cttccagaac ctccctgcac tgctccatcc cacttacaga aagcctgcgg attcccttta
     2041 catccccaag caggtctgtt aaaccatccg caatggcgat ttctctggaa cggtaggcaa
     2101 tctgctcagg ttctttctca gttatggaaa tcccttcttt tttcatccat tgcaccatct
     2161 cttccaatgt aatcacataa tccacttcat ttcctgagtc tctcaactct gacatagctg
     2221 aaatacaggg acttacatag acaatctctg ccttcggata tttttttttc agataactgg
     2281 catgaaactg catcatagag gcagactgta ccagatttcc cagaagatgc ggatagtgtt
     2341 tcttgacaag ctgtacgatt acagggcagg cagaagagat cattattccc ggctctttct
     2401 gttccgcaaa aagtgctctg tactgcgaaa tcatcaggct tgcaccttct gctgcatccg
     2461 ctgcatctgc aaatcccagc ttcttcatcg cttcccttat tccattgata ccggttaccc
     2521 caaaacgtgc cagatatgct ggatgaagag aggctataac ctgcgtctta ttctccattg
     2581 cattgcagat tgcaggaatc atattctgct cttccttggc atcctgcggg cagacaagga
     2641 tacacttctc acagtaaata cactgacttt ctatgatcct ggcctgatga tcatgaacac
     2701 gtatcgcctt aaccgggcag ttccggacac atttgtaaca atttttacaa ctgacttttt
     2761 taaactgaag gattgactga aatctctgca tgcctcgtac tccttattat gtaacactat
     2821 atttttcaca aaaaattatc tgtaaccgtt ccgtattttc acagaatgat gtactgccga
     2881 atgattattt ttgcctttcc ataaaggaat atggagctgc cgcaaggaca gcagatccat
     2941 gtgcgacagc cccatataat atttacgata tcagatccgg aactttgtct ccgatattgt
     3001 tttatgcttt ctcaatctta attgcgcata ccttatattc aggaattctt gcgtatttgt
     3061 caagtgcggc gttggtcagc cagtttgcat ttccatccgg gaagtggaat ggcatccagc
     3121 tctcacccgg tgaggtcttt gtacctacac gagcggtaga ttcaatggat cctcgtctgg
     3181 aagaaactct gactttatca ccgtttttga tacccagctt atcggcatct acgatgttca
     3241 tttcgataaa tgacttacct tcgatctcca taagctcagg tgtctttccc gtcatggctc
     3301 ttgttgtgta atgatacaga atacgtcctg tcataaggat gattggatat tcctcatccg
     3361 gaagctctgc tgacggtaca tattttgcag gatagaacca gccaagaccg cgggagaatt
     3421 taccaacatg catgatcggt gttcccggat gatccttgga ggtacatggc cactgaagtc
     3481 cctgtccatg aacttcttca ctgtcaagac gttcatggct gatacctgcg aagctcggtg
     3541 tcagggatgc gatctcatcc atgatctgag cagatgtcag atatggctgc ggatatccca
     3601 tacggttcat cagatcaata ataatatctg tatccagtct catttcgcca ggtactgtga
     3661 cagccttgcg gactctctgt acgcggcgct ctgtattggt aaatgtaccc tctttctctg
     3721 catagcttac accaggaagg ataacatctg catactgagc tgtctctgtc atgaaaagtt
     3781 cctgaagcac aaagaaatca agactcttta atgctttgat aatgtgtgtg gtatccggat
     3841 cagtaactac cgggtcctca ccatagatat acagaccttt gatctcgcct gtgattgctt
     3901 tcgggaatac atcagttgca tgagttccta tattcggatc aagttttaca ccccatgctt
     3961 tctcaaattt ctcacgaact gcaggatcag taaccttctg atatcctgga tatacattcg
     4021 gctgagcgcc catatcgcag gcaccctgta cgttattctg tccacgaagc gggttaacac
     4081 cacagccttc acgtccaagc ttaccaacca tcattgccat attggacatg gacataacgc
     4141 cctctgtacc tgtggaatgt tcggttacac caagacagta gatgattgga gcgcggtcag
     4201 cttttgcata catgatcgct gcttttctca gatcgtctgc gtcaatgtgg cagatttcag
     4261 ctaccttctc aggtgtgtaa tcttttacga tttcctttaa ttcttcaaaa ccttcggtac
     4321 gctctgcaat gaacttgtca tcctgaagac cttcagaaag gatcacattc atgatgccgt
     4381 ttgcaaaagc aacatttgta ccaggtttca gtttcagatg gatatctgct ttcttagcca
     4441 gaccaatatc acgaggatca actacgatca gcttacagcc tctcttgata gcctgacgga
     4501 tctgcatgcc gactacagga tgtgcttcct cagggttgga accaaccagc atgatcagat
     4561 ctgcattctt tgtgatatcc tcaattgggt ttgtcatggc acctgagcca agagtcatcg
     4621 caagacctga tacagatgca gaatgacata cacgtgcaca gttgtctgta ttgttggtgc
     4681 cgaagcagca gcgaaccatc ttctgtacca tgtaaatatc ttcattgggt gatctggaac
     4741 atgcaaagcc tgcaagagaa tcagagccgt actgtttctt gatctccata aatttggaag
     4801 caacaagatc cagcgcctca tcccatgttg cacgttcgaa ttcacctgtc tctttattct
     4861 tgatcagcgg atatttaata cgctccggtg actgtacgaa atcgaaacat ccgctgcgtc
     4921 ccttaacaca gagcagccct ttgttggacg gtccgtttac agcttctgta tctacgatct
     4981 ttccgtcttt tacaaggaga taatactggc agcctgttgc acagtgagga caggtagtca
     5041 gaaccttctt gtcaatctgg tacggacggt atttctttct gcgcttcatg gtcagtgcac
     5101 ctgtcggaca ggcctgtaca cagttaccgc aggattcaca gataccttcg ttccatttat
     5161 gtttgtaatg tgcaccgatc actgactgga aaccacgatc catagtgtcg atggcacctc
     5221 ttcccacaat ctccttacat gtattcacgc agcgatggca gagaatacac aggcttggat
     5281 cataggtaaa gaatttattg gtatcatcta tcggcatatc cttcatttca ccaggatagc
     5341 ttgtctcagt cacaccatat tcaaaacagt agtcctgtaa tttacagtca ccgtttgcct
     5401 cacaggagaa gcagtgtaca cgatgatcag aaagaaggag gtcaagggta tctttacgat
     5461 atgcaactac cttctctgac attgtctgta cttcatcacc ctctgagcag cgaagtgtac
     5521 atgccgtatc aaatttggtt cttccattgt ttgttacttc taccacgcac aaacgacagg
     5581 aaccatccgg caatacatct tccagatagc agagtgtagg aatctccact ccgatctgtc
     5641 tggcagcctg cagaatggtc gtaccttttt ccacttctac aggaattcca tctattgtca
     5701 aatgaatcat cttttcaccc tccttaattc acagaaattg cgccgaatac acaattttcc
     5761 agacatgttc cgcacttaat acacttggag gtatcaatgc tgtgaggctc tttcttattg
     5821 cctgtgattg caccaaccgg acagtttctc gcacacttgg tacatccttt acatttctca
     5881 ggatcgatca cataagaacg cattgcctta catacatgag ccgcgcactt tttatcaaca
     5941 atatgctcta catattcatc tctgaagttt cttaatgtgg aaagtacagg aagcggtgca
     6001 ctctttccaa gtccgcagag tgaacggtcc ttgataaagt ttccaagatg ctccagttta
     6061 tccagatcct ctacttcacc ctttccgtct acgatcctct caaggatttc aagcatacgc
     6121 ttggtgccaa tacggcaggg accacattta ccgcaggatt ctctctgggt gaagcccata
     6181 aagaaacgtg caacctctac catacaggta tgttcatcca taactaccag accaccggaa
     6241 ccaacaatcg caccgtattt cttaacagag tcgaaatcaa ggggtacatc cagatgttct
     6301 tctgtcagac atccaccgga tggtccaccg atctgaacag ccttaaacgc agcaccggat
     6361 ttcagtcctc cgccgatatc aaaaatgatt tctcttaagg ttgttcccat cgggacctcg
     6421 atcagacctg tattctcaat agaacctgtc agtgagaagg tttttgttcc aggtgatccc
     6481 tctgtaccga tacttctgta ccaatctgca cctttgagaa taatctccgg aatatttgca
     6541 taagtttcta cgttattcag aacagtaggt ttcgcccata atccctgttc aactgtacgg
     6601 ggcggtttta cacggggcat gcctctgctt ccttcgatag atgcagtcag ggcagaaccc
     6661 tcgccacata cgaaagctcc tgcaccacga ttgatatgca tatggaagga aaatcctgtt
     6721 ccaaggatgt catcgcctaa cagtcccact tcttccagaa ctgcgatagc gtgtttcagt
     6781 cgtgctacag actgaggata ctccgcacgt acataaatat aaccatgctg tgctcttact
     6841 gcgtaagctg caagcatcat accctcgatc agacggtaag gatcaccttc cattacggaa
     6901 ccatccataa atgctcccgg gtcaccctca tcaccgttac aaaccacata atgaacagga
     6961 tcagcctggc gtgctacctg aatccatttc ttacctgccg ggaagccgcc gccaccacgt
     7021 ccacggatac cggatttatc aacctgatca ataaccagat ccggatccat ctcaaacatt
     7081 gctttctcca gagcctggaa accgccgctt gctatgtact cattcagaga ttctgcatca
     7141 aacttaccac agttcttcaa aacaatacgg gtctgtttcg cgataaacgg aatatcttcc
     7201 ggtccgcggc ttactttacc gcctttctga taaagcagtc tctcgatagt ctcattaccc
     7261 tgaacactct tctcaaaaat ctcctggcag tcttcgatct gaaccttcgt atactgaatc
     7321 acatcgtcgc ctttctggat acgaacaagt ggtccaagct cacagacacc ctgacatcct
     7381 gttttcttta cacctacatg tgcatctttg tcatgaggtc caaactcaat ggtaactccc
     7441 ggagcatctt tggcaatctc catgaatttc tcatagattt tctgagaacc ggttgccaca
     7501 catccggtac ctgaacagac aagaatacga cagtcataag aattaagttc tttcacagct
     7561 tcttctctga tctgctccaa tacttcctta ttctggatca tccctgttcg ccccctctca
     7621 gtttatcaat cagctcatct gccttctccg gagtcattct cggatatacc tcttcattga
     7681 ccatcatagt cggtgcaagt ccgcaggcac caagacagga aactgtttcc acagtaaaca
     7741 tcatatcgtc tgtcgtcttc tttgtctttg acagccccag tttcttataa agttcctcca
     7801 gaaccggtat tgattttctt acatgacagg ctgttccgtc acagaccttg atcacatatt
     7861 tacctttcgc atcaaatgag aaattctcat aaaatgtggc aacactgaac gctttcgctt
     7921 ctgtcacacc gatctgctcc gcaacatatg taagcaattc ttccgggaga tatctgtaca
     7981 ccccctggat atcctgcatg atcggaatca gtgatgccgg ctttttacca tagaaagcaa
     8041 tgatctcatc cgctttctga taaaatgact gatctagcat ttcgcaccct ccttatacct
     8101 gttttttctc tttttattgc actctttaca tattgtaacg ttaattatat gcctttttcg
     8161 tcattttcac aagcgcattt atagaaattt tctaattttt tatcattttc ctctatagat
     8221 gtttgtttta tttgtctaat ttttatcagc tttgttcaat actaaaccat ctcagatgta
     8281 aaccaaacta aactgaatca aactgaataa ttgttactgt ttacgcacca ctatcccgag
     8341 acatacaagc caaaattcca ttgccgcaga caatttggaa tgaattttag ctacgttact
     8401 gagaacggag taaacagtaa tgtacgtgtg tacaatgtca gaaatattat gattgtgcta
     8461 tgattctgcc tgtgctacac tgtccatatg atatcagtga caaaagataa gtgttccgtt
     8521 ctcactgaaa atatccggat aaaggaggag gtaagtatgt tttctttgaa agaaaaagaa
     8581 gtgaatacag gacgtcagag ggaacttgat ctggtaaagg gtttcctgtt gatcatgata
     8641 gtatttatac attcatttca gacaataggt ggtgtcgcag cagccgaatc aaatgtacat
     8701 aagattctgt ttgcgctctt catgccgaca ggtgcctgcc tgtatctgtt taccatggga
     8761 ttcggaagtg ctttcacacg ccattcccag cccaaagata tggttaaaaa tggcataaag
     8821 ctgttattct atcagggatt aagcaattta tgctatgcag ctgtaatgac aatcagtttt
     8881 aatataagaa attccattac agttgaagct gcaggcagca gagaattata tgacgcaaat
     8941 ctttattcca tgcttacatt cgtaaatata ttctttatag ccggtatgtg ctatctggtg
     9001 cttgcggtct acaggaaatt aaatgtaagc ttaaggggat atgtcataag tgctgtaata
     9061 gtcggaatca tatcaccatt tacaaagttg ctggtttctg atgatccggc acttaactgg
     9121 atcctggata tgactttcgg tggaaaaggt gaaaccagct tctgcttctt cccatatttg
     9181 agttatgtat ttcttggata tgtttttgga aaagtgctca gaagaatccc tgaagatgaa
     9241 aaaggaaact tttataaaga aagcgggatc atatgtggga ttactgcggc ggtatggttt
     9301 atatgctgca ttgtactaca tccgggcatt gagggattct ttaattatat gatcgaacaa
     9361 tacagaatcc cggggcttgc aaaggtactc ggaagtttct gcagtatcat atttgtgttt
     9421 gcagctgcat ttcgtatcat gccaatgatg gaaaaatgga aattcggata taataaactg
     9481 tgttattact caaaacagat ttcaaagatg tatgccgtac atatcggagt ttactggaca
     9541 cttgccggtt ttgctgcttt ttacgaattt ggggtaaaag aatgcctgat attgtcagtg
     9601 gcagcactga tcgtgactga tcttcttgta catggataca tcataattac agataaaata
     9661 aaaaacagaa aatagcagaa tgctttttat ctgcacaaaa aaacagacca cattttatga
     9721 tctttgtttc ataaaatgtg gtctgcctgt ttcatgcgtt ctttttattg agcctggaaa
     9781 taatatccaa cgccccattt ggtgtgtaca tatttcggtt cacttggatt ggtttcaatc
     9841 ttctcacgga gacggcggat atgtacatcc acagtacgta catcacccgg atactcatat
     9901 ccccatacaa tgttcagcag gttctcacga ctgtatactt tatttggatt aaataccaga
     9961 agctccagta catcaaattc ctttgctgtc agattaatct ctttacctgc aataaataca
    10021 cgtctgcctt cacagtccat acgaagatcg cccacctgaa tgctctttgc cttttctttc
    10081 tcctcgtggt cgcttcccgc acggcgcatg atcgctttga tacgtgcctt aacttccagg
    10141 atattgaacg gtttggtgat ataatcatcc gcaccatatt caagaccaag gatcttatcc
    10201 atatcctcac ccttagctgt cagcatcacg atcggcacat tggaaaattc gcggatctgc
    10261 tggcatactt ccagcccgtc catcttcggc agcatcagat ccagaaggat aatatcatat
    10321 tttttatctt ttgctttctc tactgcctct tctccatcat aagcgcagtc tacctccata
    10381 ccatcctgtt ccagactaaa acggattcct tttacgatca gtttctcatc atctactacc
    10441 aaaactttcc tgctcattcg gttctcctta tcctactact atctcatctt ttatctttgc
    10501 aaaagtacct tctttgatac cctgtacatt cataatatcc tctatcgcag caaatggccc
    10561 gttctcttct ctgtaggcaa tgatcgcctg cgcacgtgtt gcaccgatcc ccgtcagcgt
    10621 agtaagctga gcttcatctg ctgtatttat gttgatcctg ttatcctgct gaacctgagc
    10681 ggtcatccct gtattctgtc ctgtcccggc acttccattc atctgtccat ctgatgctcc
    10741 ggccatctct gcaggatcca gcccctgccg ctccctctct tcctgtggga gaatataaag
    10801 ctgctgtcca tctgtcagaa ctcctgcacg gtttacacaa ttctgcactg cctcaggaag
    10861 atatcctccg gctgcctcaa tagcctgaaa cacccggctt ccggttgcca gctgaaagac
    10921 tcccggattt gcaactgctc cgcacacatc tacatagatc atctcaggct gtgtttcccc
    10981 ggttgaattt atctccatcc cattacctgc atctgaacca cctgattctg cctgtttttt
    11041 ccgggactct gcagaactgc catcatcatt ctgtcggtct tctgtatcag ctttcttctc
    11101 atctgtgtct ttcttcgact tctgtcctga tgttttctct tccgatgact ccgcatccac
    11161 ctctgccttt gcttcctgca atccatctat cagaaactgt gcctctctgc tcttacatcc
    11221 tgtcagtcct gtaagaaaca aagttccaca taatagccgt gtcacagtat aac
//
