LOCUS       gnlProkkaFIACMKLP_182   7829 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FIACMKLP_182.
ACCESSION   gnlProkkaFIACMKLP_182
VERSION     gnlProkkaFIACMKLP_182
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 22:03:07
            Original ID  :: gnl|Prokka|FIACMKLP_182
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7829
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7829
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[683:1426]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      684..1426
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..7829
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7829
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(2..586)
                     /NRPS_PKS="Domain: Thioesterase (17-175). E-value: 9.9e-39.
                     Score: 125.9. Matches aSDomain:
                     nrpspksdomains_ctg182_1_Thioesterase.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 210.1; E-value: 4.4e-64)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg182_1"
                     /transl_table=11
                     /translation="MNLKLIKNTENINKEKITLFCLPFAGGGASAYNQWAKKMQGKVTV
                     CPVQLPGREERIMEKPYIDMPVMLDDLEEAVREVVDGPYALWGHSMGGKISYELEKRLE
                     AEGYRAKYLFISGSRIPSIPEPKPIYHLPDEAFKRELGRFEGTPKEILENQELLDFFLP
                     MLRADFTMDETYYDKAGVVLHTPISAFGGEKD"
     aSDomain        complement(62..535)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg182_1_Thioesterase.1"
                     /evalue="9.90E-39"
                     /label="ctg182_1_Thioesterase.1"
                     /locus_tag="ctg182_1"
                     /protein_end="175"
                     /protein_start="17"
                     /score="125.9"
                     /tool="antismash"
                     /translation="TLFCLPFAGGGASAYNQWAKKMQGKVTVCPVQLPGREERIMEKPY
                     IDMPVMLDDLEEAVREVVDGPYALWGHSMGGKISYELEKRLEAEGYRAKYLFISGSRIP
                     SIPEPKPIYHLPDEAFKRELGRFEGTPKEILENQELLDFFLPMLRADFTMDETY"
     CDS_motif       complement(290..346)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg182_1_0001"
                     /evalue="3.70E-08"
                     /label="NRPS-te1"
                     /locus_tag="ctg182_1"
                     /protein_end="99"
                     /protein_start="80"
                     /score="25.8"
                     /tool="antismash"
                     /translation="DGPYALWGHSMGGKISYEL"
     CDS             complement(684..1268)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg182_2"
                     /sec_met_domain="AgrB (E-value: 1.2e-33, bitscore: 105.0,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWKKMAGRLFELQSRNGILEEKDRRLYEYAYGVLLGRVVIYLIIV
                     ILGIITGNWMEMIVFLLPFTVLRQYAGGIHLEKAGGCMAVSGILVLLCSLYLASAPAVI
                     WQMRIIWFVAVGVIFIMAPVDASSKKLDAKEKKVYGMRARVILVIECAIAGVFSVIGYS
                     LIVNGIMVAHIVLASGLILGWTKIFFDKELE"
     CDS             complement(1268..1426)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg182_3"
                     /sec_met_domain="TIGR04223 (E-value: 8.9e-13, bitscore:
                     37.1, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIRKNLGIKLLGAVNCLALCLTAYTANLACNWLYYQEDEPEE
                     VKKMRKF"
     CDS             complement(1528..2823)
                     /locus_tag="ctg182_4"
                     /transl_table=11
                     /translation="MIIRDYLICLLQMYLLEDLEKNILPYRRERFWEKFLVYCIAALAM
                     FGTNRLESSILNMVMIPVIYMIASMVVFRGNIWKKLVTVCCYYVLAIIPEFLFAALTNA
                     YGVTGASEGFRTETEKTLALLLMSTMTFLFIKCINQVTRKRDYLTIENKTFTVLLMLPT
                     ATIVMLGCMFYSHTSFEGMNRVMVPVGASLLLMTNIFIFTVFDRFVEKSEEVKKMDRLY
                     QKSRAEIANLQYMNKVNEDNRAFLHDINKFICTVAGLIEEGENQEVKDIMEHLGVRIQN
                     LQKSVYCEHPILNSILCERKFLAESKDISYRITLGNDLRLDFLEELDLISIVGNLLDNA
                     LEAAEKTEDGRYVECRMYMGNAGHFLVMEFCNGYVVPLLKDKDRYISTKRDADSHGIGL
                     HTVGKLVKKYAGIMRVEAGEREFSVKLIFTIK"
     CDS             complement(2820..3557)
                     /locus_tag="ctg182_5"
                     /transl_table=11
                     /translation="MCKIAICDDDKEYREKIKTVIETEGILSSNEIRFYEYESGKELLE
                     DADILHDLIFMDMRMPGLDGNKTVLKLREYNEAAILVFCSGCFEPTPDSINVGQPFRYI
                     MKDLHDRSLKKEIPMILLKVKLCCGDSSVTVTSAGRIMRIHTEDILYICLAKRGCTIYI
                     ARQGKIEEMHCKESLSDLYECLAGRGFEYAHNSYIVNLAKVEGLEKNVALLPFGIQLNV
                     SRSRKGQFADALITFLGERNGMV"
     CDS             complement(3646..3885)
                     /locus_tag="ctg182_6"
                     /transl_table=11
                     /translation="MDIKTAVIYRLNDLIKQKDITVNEAAVRSGVPPSTLKNILYGQSR
                     NAGVVTIKKICDGLDITIQEFFEDPIFADLEPEL"
     CDS             complement(5086..7794)
                     /locus_tag="ctg182_7"
                     /transl_table=11
                     /translation="MQKMQEYTQEQIDRAEHMEIEIPADVKVQIFEYANLIGEEEKVRT
                     LVRNLADAVSQADQEGVEDLLDDVRMDIQELPDPTIGKLELRDYGYTAEDMVPLRKEAA
                     LDYHRMGSKIYFLGSDGIKGEYASREMIQAHDGLFGMESQMWERIKDNNLDYAEENLGA
                     FQEPMSVIEQEEALKLYDAGADIYLITNFSSPMYVTERMEIERGPEHYQMSMTELERFR
                     NLEWEMQKYPQIQSLKEANLLLGTRRIFGIYQIRDDLPGENYAFMNMSFIESHGMQIKK
                     EDYKLVYVGELSGNMSLEDIFERFNIDRPEDFRGHSLSVSDIVVLNDGKKVTAHFVDSI
                     SFEQLDSFLNLEEQVLSELAYEVGERYFAIQRTEEGYDYSFYDEDFRLIDGGVYENDEI
                     SIEEAAEELLEDEGSTGARISGDYDQMMEKVEEMDEAVMAEIQKSQGEYKPLAKVEELE
                     EANYNMIDNVLNNMPPKKEPYLEYFAAECDEFHDMGAYEKSTDANQIAAVYEKYRENPK
                     TAYLGCSMGIIYHDPEDSYYDEAEFAIVKGNTVFGNLMDDVRFYGELALVREGIEKIHE
                     ALPDYKYVPMRDVREAMYPEKMTTEQLAEALDEIAEAFDPYEYRDNVEPGENTVQEVML
                     DLRSGNIHYYVSYLKDIVDEECDLSVRAGVLIERLKAYEPELPKDMQPMVYVNYCEKSE
                     LGNPRCQKLSDLDSKTIEQDKVWYADRDPKTNEPKMTAQMFFTVYYAEKGDKMLHHFQG
                     KIDIGTGNGGIISQLKMQNEMKLTDESWISYQQGKGNEEYQKYMEDLTDMQNHVLPYLQ
                     SFCSLEEKGVKERREQQVAEKNESREAVPRTGGEANIAVKDAGKAERKEITGKEKKPSI
                     HERLEINKRIIQEKQGKDEPERGADLSVRMV"
ORIGIN
        1 cgtccttttc tccgccaaat gcagagatag gtgtatgcag cactactccc gctttatcat
       61 aatacgtttc atccatggta aaatccgccc gcagcatagg cagaaagaaa tccaacaatt
      121 cctgattctc tagtatctct tttggcgtcc cttcaaatct tcccagttcc ctcttaaacg
      181 cttcatccgg aagatgatag attggcttcg gttccggaat gctgggaatc cggctgccgg
      241 aaataaacag gtatttcgct ctatatccct ctgcctccaa tcgcttttcc agctcatagg
      301 agatcttccc gcccatactg tgcccccata aggcatacgg tccgtccaca acctctctta
      361 cagcctcttc cagatcatct aacataaccg gcatatctat atacggtttc tccatgatcc
      421 gttcttccct tcccggaagc tggactggac ataccgttac ttttccctgc atctttttcg
      481 cccactgatt ataagcagac gcgccgcctc ctgcaaacgg caggcagaac aaggttattt
      541 tctctttgtt gatattttct gtatttttta tcaatttcaa attcactttt atattcctct
      601 tgtatcatgt tctttttgtt ctgtttatca tccttttgca atacgctttt cccaggtatt
      661 tcttattcct atcatggatt agttcactct aactctttat caaaaaaaat tttggtccat
      721 cctaatatta aaccagacgc caaaacaata tgcgctacca taatcccgtt tacgatcagg
      781 gaatatccga tcacagaaaa aacacctgct atcgcgcatt caataactaa aattaccctc
      841 gcgcgcatcc cataaacttt tttctctttc gcatccaact tcttgctgct ggcatctacc
      901 ggcgccatga taaatataac gccaaccgcg acaaaccata tgatccgcat ttgccatatt
      961 acagccggag cagacgccag atacagactg catagaagga caaggatacc ggaaacagcc
     1021 atgcagcccc ctgccttttc caaatgaatc cctccggcat actgccttaa aacagtaaag
     1081 ggcaataaaa agactatcat ctccatccaa ttccccgtta tgatgccaag tatgacgatg
     1141 ataaggtata ttaccaccct gcccagcagt acgccgtaag catattcata cagcctgcgg
     1201 tctttctctt caagaatccc attcctgctt tgtagttcaa aaagccgacc agccattttt
     1261 ttccacacta gaatttcctc attttcttaa cttcttccgg ctcatcttcc tgatagtaca
     1321 gccagttgca cgccagattt gccgtatacg ccgtcaagca gagtgcaaga cagtttacag
     1381 ctccaagcag tttgattccc aggttttttc tgattatttt tttcatagtt acaaagcctc
     1441 cttttttccg aaagtttaca caaaaatcgc cctcttttca attaccgcgg caaaaacggt
     1501 aactttttgg gcgatttttg cacgtcctta tttgattgta aagatcagct taacagagaa
     1561 ctcccgttct cctgcctcca ctcgcataat tcccgcatac tttttaacca gttttccaac
     1621 cgtgtgcagt ccgatcccgt gactgtccgc gtctcttttg gtgcttatgt acctgtcctt
     1681 gtcctttaac agagggacga catacccatt gcaaaattcc atgacaagga aatgccccgc
     1741 atttcccata tacatcctgc attccacata tctgccatct tctgtctttt ctgccgcttc
     1801 cagtgcgtta tccaaaagat tccctacgat cgagatcaaa tccaactctt ccagaaaatc
     1861 cagtctgaga tcattaccca gggtaatcct ataggatata tccttagatt ctgcaagaaa
     1921 ttttctttca cataggatgc tgttcaagat cggatgctca caatatacac ttttttgaag
     1981 attctgaatc cggacgccta aatgttccat gatgtcctta acctcttgat tctctccttc
     2041 ttctatcaag ccggctactg tacagataaa tttatttata tcgtgtaaga atgctctgtt
     2101 atcctcatta accttattca tatactgcag attggcaatc tccgccctgc ttttctggta
     2161 tagccggtcc atcttcttca cttcttctga tttttctaca aacctgtcaa atactgtgaa
     2221 aatgaagata ttcgtcatta acagaagcga agctcctacc ggaaccatga ccctgttcat
     2281 tccttcaaaa gaagtgtgcg aataaaacat acatcctaac ataacgatcg ttgcggttgg
     2341 cagcatgagc agcactgtaa atgttttatt ttcaatcgtc agataatccc ttttccttgt
     2401 tacctgatta atgcatttaa taaacagaaa tgtcatggta ctcatcagca ggagtgctaa
     2461 tgtcttttct gtttcagtcc tgaagccctc ggacgcacca gtcacgccat atgcattcgt
     2521 aagtgccgca aagagaaatt cgggaataat tgccagcaca taatagcagc ataccgtaac
     2581 cagcttcttc catatatttc cccggaacac aaccatagat gcgatcatat agattaccgg
     2641 aatcattacc atattaagta ttgaggattc caggcggttg gttccgaaca ttgccagtgc
     2701 tgcgatacaa tatacgagaa atttttccca gaatctttct cttctgtatg ggagtatgtt
     2761 cttttccaag tcctccaaca gatacatctg aagaagacaa atcaaataat ctcttattat
     2821 cataccatgc cgttcctttc cccaagaaat gttatcagtg cgtcggcaaa ctgtcctttt
     2881 ctcgacctcg aaacattcaa ctggattcca aacggcagca acgcaacatt cttttccaat
     2941 ccttccactt ttgccaaatt cacaatatag ctgttgtgtg catactcaaa tccccttccg
     3001 gccagacact catacagatc acttaaagat tccttgcaat gcatctcttc tatctttccc
     3061 tgtctggcaa tgtatatcgt acagcccctt ttcgccagac agatatataa aatgtcttcc
     3121 gtatggatgc gcattatcct tcccgccgat gtaactgtca cggaagaatc tccacagcac
     3181 aatttcactt ttaataaaat cataggtatt tcctttttca gacttctgtc atgcagatcc
     3241 ttcatgatgt accggaacgg ttgtccaaca ttaatgctgt caggagtcgg ttcaaaacag
     3301 ccggagcaga acaccaatat cgctgcttca ttatattccc tcagcttcag tactgtttta
     3361 tttccatcca atccaggcat acgcatatcc ataaaaatca gatcatgcaa aatatccgca
     3421 tcttccaata attcttttcc tgattcatat tcataaaacc gtatctcatt cgaagacaga
     3481 atcccttccg tttctatgac cgtctttatt ttctccctgt attctttatc atcgtcgcaa
     3541 attgctattt tacacatatt catcctccag tgttagtttc ttctaaccct ttcccataaa
     3601 aaaaccatct tgcagaatct gaatcctaag attatttgcc tgttcctata actccggttc
     3661 caaatctgcg aagatgggat cttcaaaaaa ttcctgtatt gtaatatcca atccatcgca
     3721 tatcttttta attgtaacta cgccagcatt cctgctttgt ccatacaaaa tatttttcag
     3781 tgttgaaggc gggacgcctg agcgcaccgc cgcttcattc actgtgatat ctttctgctt
     3841 aatcagatcg tttaaccgat atatgaccgc tgtttttata tccacggaat caaccacctt
     3901 tttttcttct attttatata aaccgtcttt aaaaggtcgc ccatatatag tctttttgat
     3961 ctatgtatga tattttttga cagttttcct gtttttagag aaatccgcaa aaaacctgtc
     4021 tttatcagac gcagaaaagc cccacgagaa cacatccggt cctgcgcagg gcttttcact
     4081 tatcatacta ttttccatat tttttatttt ccaatgtgcc gggccggagc ctccgttctt
     4141 ctttcccact gttgccagtc atcgttttgc ctttttcata cttttatttt tctcattctt
     4201 tcctgataaa atcattattg ttacgtctat gaaataacac cgtaaaaaaa cactgccaaa
     4261 cagacagtgc acctcatttt atgcatctgg ctgccatttt acaggccctg tagctttgcg
     4321 tcccagactt tcatctggtt tgccgatttc cttattatag ctttaatctt atgcaaaaaa
     4381 ttgattttat tatactttaa cgctcaacta tacacaagaa aaatttaccg ttttaacgcc
     4441 cgaaaaacaa aaaagaacag ccgatacata tacccgaact gttcttctac ttccgaagtc
     4501 cacgcagcat tgacattact gtttcctgct catttgtact cagatcgttc catatcccta
     4561 gaacttcttt ctgtttttct gtcagattct ctgaattatc ttcctgaaaa aactacgata
     4621 atgtcacgcc caaagctgta catatttttc aagtgtgatc agcgacggca ggttttcctg
     4681 cgccatgatt cttcccagtg acgactggga aattcccgac agttgcgata atctgcattt
     4741 actgatatca cgcttttcac atagagatgt tattttatcc gcaatatact tctctatcta
     4801 caagtaacta ttcctcattt ccgctattac atgttcttat tgcacctgta atagcagaaa
     4861 aatattagtt atcaactttg caagtattca tttccacaat aggaagcata cacataaaaa
     4921 aataaagata ctttcctttc cgcaaaagtc attttcgctt atatcatttt tataatatca
     4981 cagcaagtta cgtttatcac ataaaagttt gaagcataat cattcaaaac aaaaagccga
     5041 aagccacatt gttatctgtg acctccgact ccattctatc ttatactaca ccatccttac
     5101 actcaaatca gctcctctct ccggctcatc ttttccctgt ttttcctgga tgattctctt
     5161 attgatttcc aagcgttcat ggatcgacgg tttcttctct tttcctgtta tttcctttct
     5221 ttcagctttc cccgcatcct taactgctat atttgcttca ccgccagttc ttggcacagc
     5281 ttctctgctc tcatttttct ctgctacctg ctgttctcgt ctctccttca cacctttttc
     5341 ttccaggctg caaaagctct gcagatacgg cagtacatga ttctgcatat ctgtcagatc
     5401 ttccatatac ttctgatact cttcattgcc ttttccttgc tggtagctga tccagctttc
     5461 atctgtcaat ttcatttcat tctgcatctt taactgactg atgataccgc cgtttccggt
     5521 accaatatct atcttacctt gaaaatgatg cagcatcttg tcgcccttct cagcataata
     5581 tactgtaaaa aacatctgtg ctgtcatttt tggttcgtta gtctttggat cacgatcagc
     5641 ataccagact ttgtcctgtt ctatggtttt ggaatccaaa tcagataact tctggcatct
     5701 tggattcccc agttcacttt tctcacaata attcacatac accattggtt gcatatcttt
     5761 tggaagttcc ggttcatagg cttttagcct ttcaatcaat acacctgcac gaacagacaa
     5821 gtcgcattct tcgtctacaa tatctttcaa gtaagaaaca tagtaatgaa tatttccact
     5881 tcgcaaatcc agcattactt cctgtaccgt attttctccc ggctccacat tatcccgata
     5941 ctcatatgga tcaaacgctt ctgcaatctc atccagtgcc tctgctaact gttctgtggt
     6001 catcttctct ggatacattg cttctcgaac atcccgcatc ggaacgtact tatagtcagg
     6061 taatgcttca tgaattttct caattccttc ccgtaccaat gcaagttccc cataaaaccg
     6121 aacatcatcc atcagatttc caaacacagt atttcctttt acaattgcaa attcagcttc
     6181 atcatagtaa ctgtcttccg gatcatgata aataattccc atcgagcatc ccagatacgc
     6241 tgtttttgga ttctccctat atttttcata gactgcagca atctgattag catcggtact
     6301 tttttcatac gctcccatat catggaactc atcgcattct gccgcaaagt attccagata
     6361 tggttctttc ttcggtggca tattgttaag gacgttatca atcatgttat aatttgcctc
     6421 ttccagttcc tctacctttg ccaatggctt atattcgccc tggcttttct gaatctctgc
     6481 cattacagct tcatccattt cttctacttt ttccatcatc tgatcataat ccccactgat
     6541 gcgtgctccc gtcgagcctt cgtcttccaa aagttcctcc gccgcttctt caatagaaat
     6601 ttcatcattc tcataaacgc caccatcaat taagcggaaa tcttcatcgt aaaaggaata
     6661 atcatatcct tcttctgttc tctgaatagc aaaatatcgt tctcctacct catatgccag
     6721 ttcactaaga acctgttctt ccagattcag gaaagaatcc agctgttcaa aactgatact
     6781 gtctacaaaa tgggcagtta cctttttccc atcattcaga actacgatat cactgacaga
     6841 cagggaatgc ccacggaagt cttccggtct gtcaatgttg aacctttcaa aaatatcctc
     6901 cagtgacata tttcctgata attcaccaac atagaccagc ttataatctt ctttttttat
     6961 ctgcatacca tgactttcaa taaaactcat attcataaat gcatagtttt ctcccggtaa
     7021 atcatcccgg atctgataaa ttccaaatat ccttcttgtt cctaacaaca ggtttgcttc
     7081 tttcaaagac tgaatctgtg gatatttctg catttcccat tccaggttac ggaaacgctc
     7141 cagttctgtc atagacatct gataatgctc cggtcctcgt tcaatttcca tgcgttctgt
     7201 gacatacata ggtgatgaaa aattagtgat cagatagata tctgctcctg catcgtataa
     7261 tttcagtgct tcttcctgct caatgacact cataggctcc tgaaatgctc ctaaattttc
     7321 ttctgcataa tccaggttgt tatccttaat ccgttcccac atctgcgatt ccattccaaa
     7381 caaaccgtcg tgtgcctgta tcatttctct actcgcatat tcacctttaa tgccatcact
     7441 gccaaggaaa taaatcttag aacccattct gtgataatcc aaggctgctt cttttctaag
     7501 tggcaccata tcttctgctg tatatccata gtcacgtaat tccagcttac ctatggttgg
     7561 atccggcagt tcctgaatat ccattcttac gtcatccagc aaatcctcta caccttcttg
     7621 atctgcctga ctcactgcat ctgccagatt tcttaccaaa gtcctaactt tctcttcctc
     7681 gccgatcaga ttcgcatatt caaaaatctg tacttttaca tccgctggaa tctctatttc
     7741 catgtgttct gcacggtcta tctgttcctg cgtatattcc tgcattttct gcatttcttt
     7801 tcctgttatc atatttctcg ccattcaaa
//
