LOCUS       c00067_gnlPro..        10350 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|POEEIKGN_67.
ACCESSION   c00067_gnlPro..
VERSION     c00067_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 00:38:36
            Original ID  :: gnl|Prokka|POEEIKGN_67
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10350
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10350
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[934:6542]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      935..6542
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..10350
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10350
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             935..2653
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg67_1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.7e-49, bitscore:
                     155.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQISGNKLLVKALKEEGVEYLFGYPGACTIDISDELYKQDDVKI
                     ILPRHEQALVHEADAYARTTGKVGVCLVTSGPGATNLVTGLATANYDSVPLVCFTGQVA
                     RHLIGNDAFQEVDIVGITRSITKYGVTVRRREDLGRIIKEAFYIARTGRPGPVLIDLPK
                     DVMAELGSAEYPKNVNIRGYKPNTDVHIGQLKRAIKLLNKAKRPLFLAGGGVVISRAHE
                     IFREVVEKTKVPVVTTVMGKGSIPTDHPLYIGNLGMHGAYAANMAVSNCDVLFSIGTRF
                     NDRITGKLHEFAPHAQIIHIDIDTASISRNIQVDIPIVADAKEAITKMNEYVQECSTDK
                     WLNLIKNWKEEHPLKMRPNDLLSPMDILKEINEQFENSIIVTDVGQHQMLVSQYAEITE
                     GKQMIMSGGLGTMGYGLPGGIGAKIGNPDRPVIVISGDGGVQMNIQELATAVLEELPVI
                     LCIFNNEYLGMVRQWQKLFYGKRYAMTNLRAGALSRRTEGMEYPQYTPDFIRLAESYRA
                     KGIRVTKKEEIAAAFEEAKKNTKAPTVIEFIIDPEEMVYPMIKPGGTLEDMIMDC"
     CDS             2671..3180
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg67_2"
                     /sec_met_domain="ALS_ss_C (E-value: 3.5e-23, bitscore:
                     70.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKGMKKRWISLYVENQVGVLSKISGLFSGKSYNLDSLTVGTTED
                     PTVSRMTIATVSDDETFEQIKKQLNRMIEVIKVIDFTDVFVRMKEILYIKVFNCSKEDK
                     VELFQIAETFKAKVIDYGKDSLLLEFVQTATKNDAVVKLIKEEFHRIEVVRGGSVGIES
                     ISMMER"
     CDS             complement(3249..4505)
                     /locus_tag="ctg67_3"
                     /transl_table=11
                     /translation="VKSTERLIFHIDVNSAFLSWESARRVSQGLPDLREIPSCVGGDPK
                     KRTGIVVAKSIPAKKYGIQTGEPVAMALRKCPNLVIVPSDFELYDKCSRAFKAICASFA
                     PVMESFSIDEVFLDMTGTSLIYPDPVAAAHELKGKIHRELGFTVNVGISTNKLLAKMAS
                     DFQKPDRVHTLFPDEIPEKMWPLPIRNLLFLGKASEQKLLNQGIRTIGDLARERASNVQ
                     YWLGEKTGHQLWQYARGIDDSPVKAVPDEAKGFSVETTFNDDITSIEQVFPILLEQCDV
                     LATRMRRKDKKCNCISVTFRTLDFRNRSHQTKLENATDLTDEIYINATRLFKEFWKGQP
                     LRLIGVALTGLTDGTYEQMSLFEDTENKERHRKLDAAMDEIRMKFGNDKITRASIMNSN
                     ARIGRKAKAQMKNEKTEEP"
     CDS             5268..5981
                     /locus_tag="ctg67_4"
                     /transl_table=11
                     /translation="MYLSDIHTHSIASGHGTTCTISDMAKAASKKGLKLLGISDHGPGT
                     LASGTSSYFRSLPFYPRKRFGIDILYGVELNILDSAGHTDLSDELLNNLDYAIISMHRQ
                     NYRSGSVSQNTEAYINAMKHPAVKILGHCDDTHFPVDYETLARAALRENVIFEINEASL
                     APGGYRGDTKANAARILYLCQKYQLPVILSSDSHGKEHVGDFTYAEEFVHQLMFPETLI
                     FNNQLPRLKVFLQTR"
     CDS             6183..6542
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg67_5"
                     /sec_met_domain="ALS_ss_C (E-value: 4e-23, bitscore: 70.7,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIATVSDDKTFEQIKKQLNRMIEVIKVIDFTDVFVRMKEILYIK
                     VFNCSREDKAELFQIAETFKAKVIDYGKDSLLLEFVQTAIKNDAVVKLIKEEFHRIEVV
                     RGGSVGIESISMMER"
     CDS             6891..7529
                     /locus_tag="ctg67_6"
                     /transl_table=11
                     /translation="MNTTTTTTTTAATKRSSTLYMVELAMMIAIILLMSFTPLGYLRTP
                     GLSITLLTIPVAVGAIILGPKGGAVCGLAFGATSFYMAVTGSSAFAAALFNINPFGTFI
                     VCIVARVLEGWITGLIFAALYKSPAKKFSYYVASLACPLLNTFFFMGFLCLFFYNTDYI
                     QGIVSSLGVSNPVVFVAAFVGVQGLIEAGFCFVVGSIVSKALSVALKRA"
     CDS             7654..8619
                     /locus_tag="ctg67_7"
                     /transl_table=11
                     /translation="MSLLKEISITDLSNLRIGHASDYNAQTGVTVLYFPLGAKVGCDIS
                     GGGPASRETPLTSPVTADNPINAIVLSGGSAYGLAAADGVMNYLESQNIGYNTGAALVP
                     LVCQSCIYDLSYGDPKIRPTAKMGEEACRQAFAGTDARTGNIGAGTGATVGKLYGMKQS
                     MKSGLGIAAVSVGNFQMAAIVVVNALGDIFSPQNGQKIAGLKTPDRSGFLDSVHELYRF
                     MTPHDQFTGNTTIGAVITNGAFSKAELNKIASMTRCAYARCINPVATMADGDSIYAASI
                     GDVSVDINMAGTLAAEVMAQAIQNAIHTSRIQDEEFLKYV"
     CDS             complement(9032..10216)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 76.1; E-value: 7.9e-24)"
                     /gene_kind="transport"
                     /locus_tag="ctg67_8"
                     /sec_met_domain="MFS_1 (E-value: 1e-24, bitscore: 76.1,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTNYNRTVQACFIGYVVQAIVNNFVPLLFLTFQGSYGISLQKIT
                     LLVTFNFGIQLLVDLASIGFVDRIGYRASMILAHAMAAAGLILLTVLPECLGDPFVGLL
                     IAVMIYAIGGGLLEVLVSPVVEACPTDNKEKAMSLLHSFYCWGHVGVVLLSTLFFRICG
                     IANWKYMALVWALIPIANGIFFTRVPIAPLLDEGEKGLTMGELFKKKIFWVLMLMMLCA
                     GASEQAVSQWASTLAEKSFGINKTIGDLAGPMAFAILMGSSRAFYGKFGDKINLERFMQ
                     YSAVLCMVSYLMIAFIPVPALGILGCAVCGLSVGIMWPGTFSMAAASVKRGGTALFALL
                     ALAGDVGCSSGPTYVGMISGALNDNLKLGIFAALIFPVLMIMGIKMIGSLQKYD"
ORIGIN
        1 gaatcaactc ctttcaataa tattctactc taatatattg taaaactcaa catgtgctta
       61 tatgatttta taatttatat ttacctgtta ataaccttaa aaacatattt attatttatt
      121 ttttatatca gaaatataga aatctgtcaa ttacattact gttcactccg ttctcagtaa
      181 cgtagccaaa attcattcag gaacataaat tttacagcaa ttatccaaaa cccggttgac
      241 aatttcctct ctataaatgt ataatgtaac ccaagaaaac atttgtccac cctattcgga
      301 caatgaatat ccctatatca gccaaatgcc atgacaggga ggagtacaca accccgggaa
      361 gcacagagag aaagcggtcg gtgcgagctt tcgtgaacga attgtggaag tagcccccga
      421 gcagtgaacc aaaccgcata tccagtcaga tgatccatag atccggacag acatgccaag
      481 tagacttcaa cgtcagttcc acgttacagg aacacagtat atcagtactg acaaagtgca
      541 gagccagact ctgaatacag gtggtaccgc ggaaacattt tcgccctggg caaacaagcc
      601 cagggcgttt tttactatat tcagaattgt gggagctgct ttacagcgtt ctcagcagaa
      661 tcagcgcagc gccattctgc ccctgtatca gccaatacac agctcagaaa tttatttgtt
      721 tggtgtgcat ttgcaggagt cgtgtagatc ttagtgcctg gaaatctgcg ttgttcagaa
      781 aaatctcact gtctgagcgc agcgagtttg agatttttct gaacgctttt agcagatttt
      841 cagacactta gatctactag gctccgaaac cgcacaccaa acaaataaat ttctgagcgt
      901 cctatacaca tacacaaagg aggtttacca aaatatgaaa caaatatccg gcaacaaact
      961 cttagtcaaa gccttaaaag aagaaggcgt agaatacctc ttcggctacc ccggagcctg
     1021 taccatcgac atcagtgatg aactctacaa acaggacgat gtcaaaatca tcctcccccg
     1081 tcacgaacag gcccttgtcc acgaagcaga cgcctacgcc agaaccaccg gcaaagtcgg
     1141 cgtatgtctg gtaaccagcg gtcccggagc aaccaacctt gtaacaggac ttgcaaccgc
     1201 caactatgac agcgtacctc ttgtatgctt caccggccag gtagcccgcc acctcatcgg
     1261 caacgatgca tttcaggaag tagacatcgt aggaatcacc agaagcatca ccaaatacgg
     1321 cgttaccgtc cgcagacgtg aagacctggg acgtatcatc aaagaagcct tctacattgc
     1381 ccgcaccggc cgtccggggc ctgtccttat cgaccttcca aaggacgtaa tggcagaact
     1441 cggcagcgct gaatatccta aaaatgtaaa tatccgcgga tacaagccca acacagatgt
     1501 ccacatcggc cagctcaaac gtgccatcaa acttttaaat aaagcaaaac gtcccttatt
     1561 cctggcaggc ggcggtgtag taatctcccg cgcccatgaa attttccggg aagtagtgga
     1621 aaagacaaaa gtaccggttg tcacaaccgt aatgggaaaa ggctctatcc ccacagacca
     1681 tccgctctat atcggaaacc ttggcatgca tggtgcctat gcagcaaata tggcagtcag
     1741 caactgcgat gtgctgttct ccatcggaac cagattcaat gacagaatca ccggaaaact
     1801 tcatgaattt gcaccacatg cccagattat ccacattgat attgatacag catccatttc
     1861 ccgaaacatt caggtggata tccccattgt tgctgatgca aaagaggcta tcaccaaaat
     1921 gaacgaatac gtccaggaat gttcaacgga caagtggctt aacctgatca aaaactggaa
     1981 agaagagcat ccgcttaaaa tgcgtccaaa tgatctttta agtccgatgg atatcctgaa
     2041 agagatcaac gaacaatttg agaacagtat tatcgtaaca gatgtaggac agcatcagat
     2101 gcttgtctcc cagtatgcgg aaatcacaga gggcaaacag atgatcatgt ccggtggtct
     2161 gggaacaatg ggctatggtc ttccaggcgg catcggagcc aaaatcggaa accctgacag
     2221 accggtcatc gttatctccg gtgacggcgg tgtgcagatg aacattcagg agcttgcaac
     2281 tgcagttctg gaggagcttc cggttatcct gtgtatcttt aacaatgagt atcttggaat
     2341 ggtacgccag tggcagaagc ttttctacgg caaacgctat gctatgacca atctgcgcgc
     2401 aggagcactt tcccgccgca ctgaaggcat ggaatatcca cagtacacac cggatttcat
     2461 cagacttgca gagagctaca gggcaaaagg aatccgtgtc acaaaaaaag aggaaattgc
     2521 agcagccttc gaggaagcaa aaaagaacac aaaggcacct acagtaattg aattcatcat
     2581 tgaccctgag gaaatggttt atcctatgat caaaccaggc ggaactctag aagatatgat
     2641 tatggactgt tgatcaggag gaaaattatt atggataaag gaatgaaaaa aagatggatt
     2701 tctctctatg ttgagaacca ggtaggtgtt ctgtccaaaa tctccggact tttctccgga
     2761 aaaagctaca atctggacag tcttactgta ggaaccaccg aggaccccac agtatctcga
     2821 atgacgatcg caactgtcag tgatgatgaa acttttgagc agatcaaaaa acagttgaac
     2881 cgtatgatcg aggttattaa ggttattgat ttcacagacg tatttgtccg catgaaagag
     2941 attctgtata ttaaggtttt taactgttcc aaagaagata aggttgaact gtttcagatt
     3001 gccgaaacct tcaaggcaaa ggtcattgac tatggcaaag acagcctgct cctggaattt
     3061 gtccagacag caaccaagaa tgacgcagta gtgaaactga tcaaggaaga atttcacaga
     3121 attgaagtgg tacgtggagg aagtgtagga atcgaatcta tcagtatgat ggaacgataa
     3181 aactttttct gaaattttta taaagggagg attgtcgcat tgttcttaat gctcagtcct
     3241 ctctttactt acggttcttc cgtcttttcg tttttcatct gtgctttcgc ttttcgccca
     3301 atccgtgcat tgctgttcat aatactggca cgggtgatct tatcatttcc aaatttcatc
     3361 cggatctcat ccatagctgc atccagcttt ctgtggcgtt ctttattttc tgtatcttca
     3421 aacagagaca tctgttcata agtgccatct gtaaggcctg tcagtgccac accaatcaga
     3481 cgtagcggct gtcctttcca gaattcttta aaaagtcttg tagcatttat ataaatttca
     3541 tctgtaagat ctgtagcatt ttccagcttt gtctggtgtg aacggtttct gaaatccaaa
     3601 gtacggaaag tcacggaaat acagttgcat ttcttatctt ttctgcgcat tctggttgcc
     3661 agaacatcac actgctccaa aagtatggga aacacctgct ctatggaagt aatatcatcg
     3721 ttaaaagtag tttccacgct gaaacctttt gcctcatcag gcactgcttt tacaggggaa
     3781 tcatcgatac ctctggcata ttgccatagc tgatgtcccg ttttttcccc aagccagtac
     3841 tgcacattgg atgctctttc tcttgccaga tcaccgatgg tacggattcc ctgattcaga
     3901 agcttctgct cggaagcttt tcccagaaac agcagattac ggataggaag aggccacatt
     3961 ttctccggga tttcatccgg gaacagagtg tgtactctgt ccggcttttg aaaatctgat
     4021 gccatctttg ccaaaagctt attggtagaa attcctacat ttactgtaaa tcccagctct
     4081 ctgtgaatct tgcctttcag ctcatgagca gcagctacag ggtcaggata gatcagagaa
     4141 gtacctgtca tatccagaaa tacctcatca atggaaaaag attccatcac aggtgcaaag
     4201 gaagcacaga ttgctttaaa tgcccgggaa catttatcgt ataattcaaa atcactggga
     4261 acgatcacca gattgggaca tttccgaaga gccatggcta ctggctcgcc ggtctggatc
     4321 ccgtattttt ttgcagggat agatttggca accacgatac ctgtccgttt ctttggatct
     4381 cctcctacac aggaaggaat ttctctgaga tccggcagcc cctggctcac ccttctggct
     4441 gattcccagg aaagaaatgc actgttgaca tcaatatgaa aaattaatcg ttccgtactt
     4501 ttcactgttc ttcctccaat atatgaattg cgctcttcat atctgatgat ttcattttac
     4561 cctgatctgc tctccagggt aagaacctcg tttgtccaaa aaagtgtctt tatttacatc
     4621 atcttgtctg agctgttact gtatttatat ttgtttgatt tcactctgct atcagagttt
     4681 tgaacaacaa cgccgcactt gccatacggc agtgcggcgt ctgtatttcg ctaccggtca
     4741 cattgttccc ggtaactttt tttacttaat tctgaggatt aatttcctct cgatatatac
     4801 ttttctatta gtcataaagg ttaggagcaa tttcttcgct gtccatattt gtggaatcat
     4861 accagtatcc agttcagcct ccagccattc ataagagaat tccgggaatg tctgatgttt
     4921 gaaatttttc catgttactc ctttctcatg aagtaactgt ctacacataa gcaaacagtg
     4981 ctatcgctgt cattgatcag caataagccc ccgtgttttc atatagttcc attatacctt
     5041 ctcattttcc cgaagtcaac ataatttaac atgtatcagc cgtttatttg tgttgctttt
     5101 tatttgattt ttgttgtatt tcagttgttt ttattttgtt tcctcattga catttaaatc
     5161 ctcatctgtc atacttgaat ataacgaatg taccatcaaa cagcagcttt gcatcttccg
     5221 taaggctctt atcatatata gaaaccgctc tggaaaggag acaaacaatg tatctttctg
     5281 acatccacac acattctatc gccagcggtc acggaaccac ctgtaccatc tctgacatgg
     5341 caaaagcagc cagcaaaaaa ggactgaaac tccttgggat ttctgaccac ggcccgggaa
     5401 ctctggcttc cggaacttct tcttatttca gaagccttcc tttttatccc agaaaaagat
     5461 tcggcataga tattctttac ggagttgaac taaacatcct ggacagtgca ggacatacag
     5521 atctgtcaga tgaactgctg aacaacctgg attacgctat catcagtatg catcggcaga
     5581 actaccgttc aggctctgta tctcagaata cagaagctta catcaatgca atgaaacatc
     5641 ctgctgtaaa aatactcggc cactgcgacg atacacattt ccctgtagat tatgaaacgc
     5701 tggcaagagc agctttacgg gaaaatgtta tttttgaaat aaacgaagct tccctcgcac
     5761 ccggaggata tcggggagac acaaaagcca atgccgccag aatcctgtat ctctgtcaga
     5821 aatatcagct tcctgttatt ttgtccagcg acagccacgg aaaagaacat gttggagatt
     5881 tcacctatgc cgaagaattc gttcaccagc tcatgtttcc ggaaactctt atctttaaca
     5941 accaacttcc cagattaaaa gttttccttc agacacgtta aaagaatgtt cctcaaaggg
     6001 acattctttt attttatgca ttgttttttg cattgtgtta ttttgtttat tttctataat
     6061 ttcttgtcaa aaaagacgac attttagtac attttaatta acaaaactca cttaaccatt
     6121 tacatatctc gtgatagatc agtcttactg taggaaccac cgaggatcct acagtatccc
     6181 gaatgactat cgcaacagtc agcgatgata aaacctttga acagatcaaa aaacaattaa
     6241 accgcatgat cgaggttatc aaggtaatcg acttcacaga tgtatttgtc agaatgaaag
     6301 aaattctcta catcaaggtt ttcaactgct ccagggaaga taaagcagag ctgtttcaaa
     6361 ttgcagaaac cttcaaggca aaagtcattg actacggcaa agacagcctg cttctggaat
     6421 ttgtccagac agccatcaag aatgatgcag ttgtcaaact gatcaaggaa gaattccaca
     6481 gaatcgaagt agtacgtggt ggaagtgtgg gaattgaatc catcagcatg atggaacgct
     6541 aaatctcata atcaatattt tttacaggat atagaaacac ctctatattc tgtatttatt
     6601 ttcaaacata ctataaaata ttgcagtttt taatcaaatg tgttattgtt tacgagagcg
     6661 ttattcgaaa gaaaatgcat ctgatttcca catctgacag tctggtggat aaagtcatcc
     6721 acttcacagt ctggttaaat ttgtgaggcg acctgtaagg cgtctacaca ccggaaattt
     6781 ttcttttgtt ctgatgcata tttttcataa cgcctgatcc ccatactcta aactgtctga
     6841 aaagcagggg acgcattgcg ccgttttatc agaccaaaag gagaattcat atgaacacaa
     6901 caacaaccac tacaacaacg gctgcaacaa aaagaagcag cactctttac atggtagagc
     6961 tggctatgat gatcgccatt attctgctca tgtcctttac cccgctgggc taccttcgta
     7021 ctcccggctt atccatcact cttctcacca tcccggtagc tgtaggagct atcatcctcg
     7081 gaccgaaagg tggtgctgta tgcggacttg ctttcggtgc aaccagcttc tatatggctg
     7141 tcacaggaag ttcagctttc gctgctgcac tttttaacat taatccattt ggcactttta
     7201 ttgtatgtat cgtggcacgt gtgctggaag gatggatcac aggacttatt ttcgcagcat
     7261 tatataaatc accggcgaag aaattttcct attacgttgc ttcactggca tgcccgttac
     7321 tgaatacttt cttcttcatg ggctttttat gtctcttctt ctacaacaca gattacattc
     7381 agggtattgt ttccagtctt ggagtaagca atcctgttgt cttcgttgct gcttttgtgg
     7441 gcgttcaggg actgatcgaa gcgggcttct gctttgtagt gggaagcatc gtttccaagg
     7501 cactttctgt ggcactgaaa cgtgcataat ctttaaaaga acagccgttt accaaacaac
     7561 cctgactaca ttgtcactgt agtcaggatt tttttatccg gcacatttaa agcaggaacc
     7621 ctacctgatt cggttaatac aaaggagatt tttatgtcat tattaaaaga gatttctatt
     7681 acagatcttt caaatttacg catcggtcat gcttccgatt ataatgccca gaccggggta
     7741 accgttcttt acttcccact gggtgcaaaa gttggctgtg atatcagcgg tggcggtcct
     7801 gcttccaggg aaactcctct cacctctcct gtcactgccg acaatcccat caatgctatt
     7861 gtcttgtccg gaggttctgc ctatggactg gctgctgctg acggtgtgat gaactatctg
     7921 gaatcacaaa atatcggtta taacaccggt gcagccctgg ttcctcttgt atgccagtcc
     7981 tgtatctatg acctctctta cggagatcct aaaatacgtc caactgcaaa aatgggcgaa
     8041 gaagcctgcc gtcaggcatt tgcaggaaca gatgccagaa ccgggaatat cggcgcaggt
     8101 accggtgcaa ctgtgggaaa actttacggt atgaaacaat ccatgaagtc aggtcttggt
     8161 attgccgctg tatcagtggg aaatttccag atggccgcaa ttgtcgttgt caatgcactg
     8221 ggagatatct ttagtccaca aaatggtcag aaaatcgcag ggctgaaaac gcctgacaga
     8281 agcgggtttc tggatagtgt ccacgaatta taccgcttta tgacacctca tgaccagttt
     8341 accggcaata ccaccatcgg ggctgtgatc accaatgggg cattttcaaa ggctgaactg
     8401 aataaaattg cctctatgac ccgctgtgcc tatgccagat gcatcaatcc tgtagcaact
     8461 atggctgacg gcgattccat ctatgctgcc agcattggcg atgtttctgt agatatcaat
     8521 atggcaggaa ctctcgccgc agaagtcatg gctcaggcta tccaaaatgc catccatact
     8581 tcccggatcc aggatgaaga atttttgaaa tatgtataac agtccgctat aaaagcgcag
     8641 agaaaaagta tcatctctgc gcttttattc ttcctgtctg tcttcatttt tcatctgtgc
     8701 tctggttttt ctccaagcca gagctgtaca tttgcttccc gttcccttgc cagatcacca
     8761 atagtacgga ttccctgatt cagaagcttc tgctcggagg cttttcccag aaataacagg
     8821 ttacggacag gaagtggcca cattttctcc ggtatttcgt ccgggaacag cgtgtgtact
     8881 ctgtccgttt ctttggatct cctcccacac aggagggaat ctccctgaga tccggcagcc
     8941 cctggcttac acttctggct gactcccagg aaagaaatgc gctgtttaca tcaatatgaa
     9001 aaattaatcg ttccatactt tttaatatat ctcaatcata tttttgcaga cttccaatca
     9061 tcttaatccc cattatcatc aacacaggga aaatcagtgc cgcaaagatt ccaagtttca
     9121 gattatcatt cagtgctcct gaaatcatcc ccacataggt tggtccggat gagcatccca
     9181 catctccagc aagggcaagg agggcaaaca gggctgttcc gccacgcttt actgaggcag
     9241 ccgccatgct gaaggttccc ggccacataa tacctacaga cagaccgcaa accgcacatc
     9301 caaggattcc caacgcaggt accgggataa atgcgatcat cagataggaa accatgcaca
     9361 gaactgcact gtattgcata aagcgttcca gattgatttt atctccaaat ttcccataaa
     9421 atgcccttga gcttcccata agaattgcaa acgccatggg acctgccaga tccccgatag
     9481 ttttattgat tccaaagctt ttctcagcca gagtagaagc ccactggctt accgcctgct
     9541 cactggctcc tgcacagagc atcattaaca tcagaaccca gaagattttt ttcttaaaaa
     9601 gctctcccat agtcagcccc ttttcaccct catccagcag tggagcaatg ggaactctgg
     9661 taaaaaagat tccatttgca atgggaatca atgcccacac cagcgccata tatttccagt
     9721 ttgcaatccc gcaaatacga aagaataatg tagaaagaag taccactccc acatgtcccc
     9781 aacagtaaaa ggaatgaagg agactcattg ctttttcctt attatctgta gggcaggctt
     9841 ccaccacagg acttaccagc acctccagca atccgcctcc gatggcatag atcataactg
     9901 caatgagaag tcccacaaac ggatctccca ggcactccgg caatactgtg agcaaaatca
     9961 gacctgcagc cgccattgca tgtgccagga tcatagatgc acgataacct attctgtcca
    10021 caaatccaat cgatgccaga tctaccagca actggatccc gaaattaaaa gtaaccagaa
    10081 gtgtgatctt ctgcagcgaa atcccgtaac tgccctgaaa tgtcagaaac agcagaggaa
    10141 cgaaattgtt cacaatggcc tgcactacat atccgataaa acaggcctgc actgttctgt
    10201 tgtaatttgt tttcatccga tgttatatcc tccaatctga aatttattaa gctgacatca
    10261 ttcagacatt gatccaccaa acttctatat ctccacagtt ctaatagatt tctatccgtc
    10321 aataatgaca gtgtatcaca gattctctcc
//
