LOCUS       c00130_gnlPro..         9871 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|POEEIKGN_130.
ACCESSION   c00130_gnlPro..
VERSION     c00130_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 00:38:36
            Original ID  :: gnl|Prokka|POEEIKGN_130
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9871
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9871
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[108:3357]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      109..3357
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..9871
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9871
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(3..161)
                     /locus_tag="ctg130_1"
                     /transl_table=11
                     /translation="VRLSDISDTKTLRAGFPDICRAIKEKETDMEVTEKNRTKYRMPGE
                     FEPHEGCV"
     CDS             complement(109..1230)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg130_2"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.6e-15,
                     bitscore: 46.4, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TAQLKKFKDVCTRASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             complement(1220..2500)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg130_3"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 3.1e-44, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 1.4e-36,
                     bitscore: 114.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKVDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             complement(2497..3357)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg130_4"
                     /sec_met_domain="Spermine_synth (E-value: 2.5e-54,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 3.7e-16,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             complement(3360..4817)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg130_5"
                     /sec_met_domain="OKR_DC_1_C (E-value: 2e-14, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 8.8e-127,
                     bitscore: 412.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLINNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEYLQVLKGGI"
     CDS             6107..7792
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg130_6"
                     /sec_met_domain="FTHFS (E-value: 3.5e-276, bitscore: 905.7,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             complement(7901..9325)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg130_7"
                     /sec_met_domain="Lyase_1 (E-value: 1.9e-95, bitscore:
                     308.9, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 7e-23, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             9441..9869
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     60.1; E-value: 5.2e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg130_8"
                     /sec_met_domain="LysR_substrate (E-value: 1.1e-14,
                     bitscore: 43.3, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 6.7e-20, bitscore: 60.1,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLV"
ORIGIN
        1 accacacaac cctcatgagg ctcaaattct ccgggcatac gatattttgt tctgttcttc
       61 tctgtaactt ccatgtctgt ctccttttct ttgatagccc ggcagatatc aggaaagccg
      121 gctcttaaag tcttcgtatc cgaaatgtct gataacctca cactctccgt cctcatgcat
      181 aaccgcaata tccggcagcg gcataccgtt aaatgtatta ttcttcacca tagaataaat
      241 cgccatatcc ataaaataca gcttgtcccc gatccggatc tctctgtcaa aggaataatc
      301 tccgatcaca tctcctgcca ggcaggtgca ggaagataag cggtaggtat atgccttctc
      361 ccctgcttcc ccgctgtcct taagaggcgg acgatagggc atctccagca catccggcat
      421 atggcaggct gcagaagcat ccaaaatcag cgttctgatc tcattttcca caatgtccat
      481 aacctctgtc accagatatc cggcattcag ggcaacagcc tccccgggct ccagataaat
      541 atccagatca taggtttcct tcatatgctg aatacatttt tccaggagct ttacatcata
      601 atcctctctg gtaatgtgat gtccgccgcc catattcaac caggaaacct cagacagaaa
      661 ttctccaaac ttctcctcta ctgcctgcaa tgttttctcc aggtcatctg cattctgttc
      721 gcagagcgta tggaaatgca gtccgtcgat ccatttcaga cattccccgt caaagttctc
      781 tctggtaacc cccagcctgg aacccggcgc acagggatca tagattgcat gatccccctg
      841 agtggagcat tccggattaa tacggagtcc cagactggct ctggtacaca catctttaaa
      901 tttcttcagc tgtgctgtgg aattaaagat aatatggtca cagatccgat ccagttcctc
      961 tatatcttct gtacggtaag caggggaaaa aacatgattc tctttcccca tctcttcata
     1021 tccaagcctt gcctcaaaca gaccgctggc agtggtacct gccagatatt ttccgatcat
     1081 gggatacaga gcaaagccgg aaaacgcttt ctgcgccaga aggatcttac acccggtatc
     1141 ctcctggact tttttcaaaa tctccagatt ctcccgcatc ttcttctcat cgatcacata
     1201 gcagggagtt tgcagttgat caatcttcat tggctttcca gacctttacc agttcaggat
     1261 cttcgcagac tttccatgga agtccccatt tgttcagtgc ttccatatat ggatccggat
     1321 caaattcttc cacattaaat acacccggct tcttccactg tccggtcact accatcatgg
     1381 aaccgatcat agccggaaca cctgttgtat aggagattgc ttgggattcc acctctttat
     1441 agcattcctg atgatcacat acattataaa tataaatact tttctctttt ccgtccttaa
     1501 cacctgtgaa aatacagcca atatttgttt tacccactgt tctcggaccc agagatgcag
     1561 gatccggcag aagagctttc aaaaactgga tcggcacgat ctcctgtcca ttaaattcca
     1621 caggtgcggt ggaaagcatt cctacatttt ccagacattt catatgtgtc agatagctct
     1681 gtccgaatgt cataaagaaa cggatcctct gtactcccgg aatatttttt gccagtgatt
     1741 caatctcttc atgatgaaga agatacatat ccttctttcc tacctcaggg aaatcgtaga
     1801 cagatttaaa ttccataggc tctgtttcta cccaatgtcc gtcttcccag taggaaccat
     1861 ttgcggaaac ctctcgaaga ttgatctccg ggttaaagtt tgtggcaaaa ggatatccat
     1921 gatcaccgcc gttacagtcc agaatatcaa tggtatggat ttcatcaaaa taatgcttca
     1981 gggcataggc actaaataca ctggtaacac ccggatcaaa accggttccc agaagagcag
     2041 tcagtcctgc ttccttaaat ttctcatcat aagcccactg ccaggaataa tcgaaatatg
     2101 cagtaaagcc tttttcttta catctctttt cgtagattgc acgccatgtg ggatcttctg
     2161 tatcctctgc ttcataattg gcagtatcaa tataatccgc accggcttcc agacatgcat
     2221 ccatgatggt aagatcctga tatggaagtg ccacattcag gacagcatcc ggcttatagg
     2281 ctctgatcaa ttctgcgacc tctgctgcat tatccgcatc tacctttgct gtctcaattt
     2341 ttgtcttcgt tgtactttca atcttctctt tgagtgcatc gcatttttcc tttgtcctgc
     2401 ttgcgatcat aatctctgta aaaacatcgc tgttctgaca gcatttgcga attgccactg
     2461 aagctacccc accacatccg attaccaata atctgctcat aaactgtttt cctcctcttc
     2521 cagtaaatct tctacatatt ttggaagcat aaatgctcct ctgtgaaggt ttgttgtata
     2581 ataccatgtt tctatattaa gattatcaaa cctctccggc ctgaaatctt ccagtggatg
     2641 atatttcttt gatgcaaatc caaaaagcca gtatcccgag ggacaggtag ggatatgtgc
     2701 ctgataaacc ctgctcaccg gaaatgaccg gaaaaccttt ctgtgcatct ttctgcattc
     2761 cacctcatcc tcatcataaa aaggacttcc atgctgataa accatgattc cgtcatctct
     2821 gagagcctta taacagcttc cgtagaattc ctttgtaaaa agtccctctg tatgtcccaa
     2881 cggatctgtg gaatcattga tgatcaggtc atatctggcc tttttattcc gcaggaaccg
     2941 aaggccgtct tcataataaa tgttgactct ctcatccttc agtccctggg caatatccgg
     3001 aaacatctcc gcacatacat ccacaaacat tttatcggat tccaccacat caatgctctc
     3061 aatctgtgga taatggatca gttctctggc aactccaccg tcaccgccgc cgatgatcag
     3121 aacatttttt acattgggat gtactgtcat tggcacatgc gtgaccattt catcataaat
     3181 aaattcatct ttatcagaga atacgatctc accgtccaga gccacaaatc ttccaaattc
     3241 ttcagactca aacacatcga ttctctgaaa ttcactttcc cctgaaaata actgtcggtt
     3301 aatccggaca gaaagcttta catttcctgt atggaactcg gaataccata attccatgat
     3361 cagatacccc ctttcagaac ctgaagatat tctaccttcg gatcctccat tccctgcatg
     3421 gaacagcctt tgtctcttgc ataaagaatg tattctacaa tttcctgtgt caccatttct
     3481 ccaggagcaa gaatcgggat tcccggagga taacacataa caaattcacc gctgatcctg
     3541 cctgccgcct gttccatggg cagagattct ttctccgcat aaaatgcctg ctgtggagac
     3601 gccaccactg caggtgcgat atattccccg gaaagcatac ctgtgctgtc cttcttatac
     3661 agacgttcaa tatcagccaa tgcccctacc agtctctcaa tatcctgaag cctgtctcca
     3721 atggaaatgt aagccagaat attacagata tctccaaact cgatctgaat atcatattca
     3781 tctctgagaa gatcataaac ttcaatacct gccagcccat ttcccagtgt ataaatggag
     3841 agttttgtaa catcaaaatc aaaaacactg gttccattga tcagatccat accatatgca
     3901 taataaccgc cgatctcatt gatctcctct ctggcatact gcgccatccc tgcaaccttt
     3961 tcaaaggatt cctctcccct gagtgccaga tttcttctgg agatatccag actggacaac
     4021 agaagataag aagcgcttgt ggtctgagtc agattgatga tctggcgcac tttctctgca
     4081 ttcatactct tattcaaaag cagcagcgaa ctctgtgtca gacttccgcc ggatttgtgc
     4141 atggaaactg ccgccatgtc agcacctgcc gccattccgg atacaggaag gtttctgccg
     4201 aaataaagat gggttccatg agcctcatct gccagcacct tcattcctct tgcatgagcc
     4261 ttctttacga tagtccgcag atccgaacag attccataat aggtagggtt atttataaga
     4321 actgccaccg catccggatt ctcatccata gccttttcca cctgactgac ttccatgcca
     4381 agggaaatgc ccagctgcgc attcacctcc gggtttacat aaaccggaat tgcaccgcac
     4441 agtaccaggg cattgatggc acttttatgt acatttcgcg gcagaatgat cttatcccct
     4501 gccttgcaga cagacaggat catgctctgc actgcagatg tggttcctcc taccataagg
     4561 aatgcatgcg ctgcgccaaa agcatctgct gcaagctcct ccgcttctct gatcaccgaa
     4621 accgggtggc agagattgtc cagcggcttc atagaattaa catccagccc cacacatttc
     4681 tctcccagca actgtgcaag ctccggattt cctcttcctc ttttatgtcc cggcacatca
     4741 aagggaacga ctctcttctt tcggaaacgt tccagtgctt catatatggg cgcatgctgt
     4801 tgtctttcat aatccatttg acatgttcct cttttcctgt cgtcatgtac cggcaaatat
     4861 agttctatca ttcagcaatt gtatactgcc tcaaaccggc acaatgattc aattatttct
     4921 ctatatattc aagtcgaacg catgtgagac acatcctcgc aaagcgttta tctccaacca
     4981 tatcctttat atttgctata tctgcacaaa aaaagaagca gataagttca ttcaccatct
     5041 gcttctctca tgatctatag aatttctcag gctctgtctc tttatatact aaccggattt
     5101 cccgtataaa tccgtctgta tcctgtgcct gttcccgtat tctgaaatat tcatgactgc
     5161 tgtcgtcttc aatcgctggc aaatatatgc tatgctctta ttgaccgttt cacaagatga
     5221 tgtgtgctta cgcactgatt attataaagt aatcaactta taaaatttga gcttctaact
     5281 caatcaataa tgtggtgtct cccacccggc aactgccccg cctgtccgta tggcttaaca
     5341 ttcagaaact gtctctgaat gtgagcaaat atttgcatga aaacgatagt gtcttttcat
     5401 actaaagatg agaataacat atcttctgaa ctgttgtcaa ttccattttc catattttgc
     5461 actagagcgt gtctgaaaaa ggctttctgc aagatgtgcg tcacaatttg agggatattt
     5521 tgccctgatg agggcgccgt agcgggctac ggcaactgaa ttcgggtgaa atatcccgca
     5581 aagtgggggc gtgcagattg cgggaatgat ttttcagaca cgctctagct ttacccgctt
     5641 tttatatttt cttcatttat cagggaaaac tgtgtttatt ttttaacaat ttctttcctt
     5701 gagaaaacgt attttctttc attaccaggg attacgattc tcttctctta tcaatttgca
     5761 caacttttat ccagtttact cacatttttt gacgtttcaa caaaaatttt cttgacattt
     5821 ttttctcaaa atgatatatt gtattcatca attgaaagaa ccttcgagta ctgacggaaa
     5881 gagtggagtg caaaccacgt ggagtcggag gtttgtggga gccgaccgtc tgggcagtat
     5941 ttgaaatatt cagatactgg ccttttttta taactttcag ggcagaaatc aggaatacca
     6001 ggcagaccgg ccaatacttc tttcaattaa taattgttgc tgatcgcgga gtgaacagca
     6061 acagaagttt ttcatgttat gcggaaacga aaggagaaaa acaattatgg gattcaaatc
     6121 agacattgaa attgcacagg aatgcgagat gcttccaatt actcagatcg cagagaaagc
     6181 aggtattgac gacaaatatc tggagcagta cggaaaatac aaagcaaaaa tcgactacaa
     6241 tcttctgaaa gaaagtgata agaaggatgg aaaattaatc ctcgttacag ctatcaaccc
     6301 aactccagca ggagaaggta aaactactac tactgtaggt cttgcagatg gtatgcagag
     6361 acttggcaag agtgttatgg tagctcttcg tgagccatcc ttaggaccgg tattcggtgt
     6421 aaaaggtggt gcagcaggcg gcggatatgc acaggttgtt cctatggaag atattaacct
     6481 tcacttcaca ggtgacttcc atgccattgg cgcagctaac aacttactgg cagctatgat
     6541 cgataaccat atcttccagg gcaatgcatt aaacatcgac ccacgtaaga tcacatggag
     6601 aagatgtgta gatatgaacg accgtcagct tcgtaacgta gtagatggtc ttggcggaaa
     6661 gacaaacggt atgcctcgtg aagacggata cgacatcaca gttgcatctg aaatcatggc
     6721 agttctctgt cttgcaagcg acatcaaaga cctgaaagaa agattatcca agatcatcat
     6781 cggatataca tacggaaaag tttccgagca gaaacctgta acagcaggtg accttcacgc
     6841 agaaggcgct atgacagccc tgttaaaaga tgctctgaaa ccaaaccttg tacagactct
     6901 ggaacacgtt cctgcaatcg tacatggcgg accattcgca aacatcgctc atggatgtaa
     6961 ctctgtaaca gctacaaaga tggctatgaa gcttgctgat tatgcaatca cagaagctgg
     7021 tttcggtgct gaccttggtg ctgagaaatt ccttgatatc aaatgccgta tggctggttt
     7081 aaaaccaagc gcagttgtaa tcgtagctac agtacgtgcc ctgaaataca acggcggcgt
     7141 tgctaaagct gaccttaaca atgaaaacct ggaagctctt gaaaaaggta tcccgaacct
     7201 gttaaaacac gtttccaaca tcaaaaacgt atacaaactt ccatgtgttg ttgctatcaa
     7261 cgcattccct acagatacaa aagcagagct tgactttgta gaagctaaat gtaaagaact
     7321 gggcgttaac gttgctcttt ctgaagtatg ggcaaaaggc ggcgaaggcg gaatcaaact
     7381 tgcagaagaa gttatccgtc ttgttgaaga accaaacgac ttctcctatg catatgaact
     7441 ggaaggttct atcgaagaca aactgaacca gatcgttcag aaagtatatg gcggtaagaa
     7501 agtagttctg acagctaacg ctcagaaaca ggcgaaacag ttagaagctc ttggctttgg
     7561 caactgcccg atctgtgtag ctaagacaca gtacagctta acagatgacc agactaaact
     7621 gggtgctcct actgacttcg aagttacagt acgtaacctg aagatttccg ctggtgcagg
     7681 atttatcgta gctcttacag gcgagatcat gacaatgcca ggtcttccta aagttccggc
     7741 tgctgaaaga atcgatgtag acgagacagg taagatcaca gggctgttct aatccggttg
     7801 aaatcaatcg aataattcaa aaatataaaa atcatattta tatatgatat gtgtccagac
     7861 gattttacag gcgggaagat tttcccgcct gtttttttct ttattttttt ataagataat
     7921 cttttccgga aataccaggt tccgtcatat ggatcggatc cagaatgcga ttaagttcat
     7981 cctcgtccat aagcttttct ttcagaatca gacttcttac agattcgcct gtcttaattg
     8041 ccttttttgc aatatccgca gccttctgat atccaagatg ggggctgatt gcagtgataa
     8101 tacctacact gttttctacc agataacggc atctttcttc atttgccgta attcctacaa
     8161 tacaattatc taccaatgtc tggactgcat agccaagagt atcgatagac tgaaacatgc
     8221 aatagaaaat aatcggctca aacgcattta attccagctg accagcctct gcagccatgg
     8281 taatggtaac atcattacca ataatattaa aagcaacttg attcactact tcaggaataa
     8341 ccggattaac tttacctggc ataatagagg aaccattctg ttttgccgga agattaatct
     8401 ccccaaaacc agtacgtgga ccggaggaca tcagacggag atcatttgac attttggaaa
     8461 gagttaccgc acatgctttc acagcaccgg aaacggctac aaatggatcc agattctgag
     8521 tggaatcaat cagatcaaaa gcctgtataa agtccattcc cgatatttca gtgagatttg
     8581 gaacaattct tctcagatag ccctcatctg cattaattcc tgttccaata gcagtacctc
     8641 ccatattaag agtccgcatt tcatccattg ctttatccat tctgtggata tcacgcatga
     8701 ttgctaccga atatgcctta aattcctgtc ccagacgaat tggtactgca tcctgcatct
     8761 gtgtacgccc catttttatt atgtgatcaa actctgtagc tttttcatta agagcatcat
     8821 agaggcgaag aagctgtttt ttcagattct gcaacaaacg aagagaagtc attttaccgg
     8881 cagtaggaat aacgtcattg gtagactgtc cacaattcac atcatcgtta ggatttataa
     8941 ttgtataatc gccttttttt cctcccagta tctcaatcgc gcgatttgca attacttcat
     9001 tggcattcat atttaaagat gtgccagctc ctccctgaac aggatccaca ataaattcat
     9061 tatggaattt tcctgaaaca atttcatcac atgcctggac aatcgcctgt gcttttttct
     9121 tctcaagaag ccccacctca caattggtta tcgctgctgc tttttttatg tatgcaagac
     9181 tgttaataat ttccggatgc atattcagcc ccgtaatgtg gaaattttca gccgcacgta
     9241 aggattgtac tccataatat acatcttccg gaatatcctt tacaccaata gaatcccttt
     9301 ctacacgata gtctgttttt ttcatagtta ttcgccctcc catgtatttg ccctcattat
     9361 atatctctgc tataatataa tcaaatacat atatttttat aaaatatata gtgtttaaat
     9421 tatatatcgg aggagtttat atgtttcagg gaatggaata catctatgag gtctacaagg
     9481 aaaaaagctt ttccaaagct gctgctgctc ttttcatttc gcagccttct ttaagcgcca
     9541 atgtaaaacg tgtggaaaac cgtattggct atcctatttt tgatcgaagt accaaacctt
     9601 tacagttaac tgaagtcgga aaacattata tacaggctgt tgaaaaagtc atggatattg
     9661 aaaataatct cgaaaactac ctactggatc tgggaaatct caaaacagga actcttaatg
     9721 taggtggcag taactttttt tcttcgtgga ttctgcctcc ccttattgct gatttttccc
     9781 aaaaattccc ccatgttcaa atttctcttg tagaagaaag tacagcaaag ctatcccagt
     9841 ttctccaggc cggaaagtta gatctggtaa t
//
