LOCUS       gnlProkkaCANMOLPM_366  10826 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CANMOLPM_366.
ACCESSION   gnlProkkaCANMOLPM_366
VERSION     gnlProkkaCANMOLPM_366
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 02:51:37
            Original ID  :: gnl|Prokka|CANMOLPM_366
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10826
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10826
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7163:8752]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7164..8752
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..10826
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10826
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             complement(2..2140)
                     /locus_tag="ctg366_1"
                     /transl_table=11
                     /translation="MTEITKSTEAKKDEMQVEKEKLESVKRADAAVKTMHDFTSPEVLY
                     KELINSVLKYHPSTDISMIEKAYKVASEAHEGQKRKSGEPYIIHPLCVAIILADLELDK
                     ETIVAGLLHDAVEDTWMTYEEVEKEFGSEVALLVDGVTKLGQLSYSADKVEVQAENLRK
                     MFLAMAKDIRVILIKLADRLHNMRTLQYMRPEKQQEKARETMDIYAPIAMRLGISKIKV
                     ELDDLSLKYLKPDVYYDLVHKVALRKSEREQFVGAIVKEVKKHMDDANIKAQVDGRVKH
                     FFSIYKKMVNQDKTIDQIYDLFAVRILVDTVKDCYAALGVIHEMYKPIPGRFKDYIAMP
                     KPNMYQSLHTTLIGPNGQPFEIQIRTYEMHRTAEYGIAAHWKYKESSDGKAPVGKSEEE
                     KLNWLRQILEWQRDMSDNKEFMSLLKNDLDLFADSVYCFTPQGDVKTLPSGSTPVDFAY
                     SVHSAVGNKMVGARVNGKLVPIEYEIKNGDRIEIITSQNSQGPSRDWLKLVKSTQAKNK
                     INQWFKKELKEDNILKGKEMLAQYARAKGFKIANYTKTQYLEAVLRKYGFRDWDSVLAA
                     IGHGGLKEGQVFNKLVEAYDKENKKNLTDEQVLEAASETQEKLHIAKSKSGIVVKGIHD
                     VAVRFSKCCNPIPGDEIVGFVTRGRGITIHRTDCVNVLNMSETDRTRLIEAEWQQPDTK
                     EKEKYMAEIQVYANNRTGL"
     CDS             complement(2178..2702)
                     /locus_tag="ctg366_2"
                     /transl_table=11
                     /translation="MKKIEDYVLSIPDFPEPGIIFRDITSVLQDADGLQLAIDSMQDCL
                     KDIDVDVIAGTESRGFIFGVPIAYNLHKPFVPIRKKGKLPRETVSVSYDLEYGSAEIEM
                     HKDSIKPGQKVVIVDDLIATGGTIEAAIKLVEQLGGEVVKVVFLMELAGLKGRERLNGY
                     DVASVICYDGK"
     CDS             complement(2850..4562)
                     /locus_tag="ctg366_3"
                     /transl_table=11
                     /translation="MEKWVIAAKRADFNQIGQQFHIDPVIARLIRNRDVIGEDKIREYL
                     SGTVQELPSPWLMKDMEKAVDILEKKISQKAKVRIIGDYDIDGVTSTYILMKGLARIGA
                     DVDTYIPDRVADGYGIHAHLIERAETDRIDTIVTCDNGIAAAAEIQMAKDKGMTVIITD
                     HHEVPYREEKGERQMVLPPADAILNPKQYDCPYPNKNLCGAVVAFKYIAALYERFGVPA
                     EELEDYYELAAIATVGDVMDLQGENRILVKEGLYRLKNTKNQGLQELIRANSLEDAKIT
                     AYHIGFVLGPCINASGRLDTAARSLALLNAKTKEEAARLAGDLTALNQSRKALTEKGKE
                     EAIRIIETTELKNDRVLVVYLPDCHESLAGIIAGRIREKYHRPAFVLTGGETSAKGSGR
                     SIESYSMYEELVKCADLMIQFGGHPMAAGLSIEEKNIEEFRRRLNVNCTLTDEELRPKI
                     VIDVPMPVSYITKELVEQISLLEPFGKGNTKPVFAQKNLRVLDHSIIGKNKNVVKLKLL
                     DPQGISVEGIYFGEAEDFVNFIREKDSISVTYYPEINRFRGRESLQIIIQNYC"
     CDS             complement(4644..7052)
                     /locus_tag="ctg366_4"
                     /transl_table=11
                     /translation="MKKSKGIVVLLLTLILTVFFCFTAAVGIGPTGTGAAKHINTGLDL
                     AGGVSITYQAKESNPTSEEMSDTIYKLQKRVEQYSTEAQVYQEGSDRITVEIPGVTDAD
                     TILNDLGKPGSLYFITKEDADGNQNFTTGQDGYVLSRTMDEIKESGSVVLEGSDVADAQ
                     GGAIQNQNTSAKEYVVSLTLTSDGENSGKTKFAEATKNNVGKQIAIVYDNNIISAPNVN
                     EEISGGKAQISGMSDLEEAQNLASYIRIGSLGLELEELRSSVVAAQLGEEAISTSVLAG
                     AIGLIIVIIFMIIAYRVPGVVAGIALILYTSLMLITLNAFDITLTLPGIAGIILGIGMA
                     VDANVIIYARIREEIGAGVSVRNSIKSGFSKAFSAIFDGNITTLIAAFVLMWLGSGTVK
                     GFAYTLALGIVISMFTALVVSRLIVNALYAVGVRDPKFYGSAKERKAVDFLGKKKVFFA
                     ISIILILCGPAAMFANSQAGNKALNYSLEFSGGTSTTVTFNEDMDIKTIDSEVTPVVEE
                     VTGDKNVQPTKVVGTNQVVIKTRSLNQSEREALQSALVEKFGVDDSTISTESISSTVSS
                     EMRRDAIVAVIVATICMLLYIWFRFKDIRFASSAVLALLHDVLVVLAFYAIARVSVGNT
                     FIACMLTIVGYSINATIVIFDRIRENLHSGSREKLAEIVNTSITQTLTRSIYTSFTTFV
                     MVAVLYIMGVSSIREFAAPLMVGVLVGAYSSVCITGALWYVMKKKFAGKGQPAIAAASA
                     SAKSSSKPKKARDVSQKDPTQPKKKNRKRVAERLAAEEAAKKQQNDDAE"
     CDS             complement(7164..8531)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg366_5"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 9.2e-30,
                     bitscore: 92.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.3e-17, bitscore: 51.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 5.4e-15, bitscore: 45.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.4e-20, bitscore:
                     62.7, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLIHRYKSNGFNIVLDINSGCIHLVDEVTYEVLPYLEEGLGTEA
                     IAEKLENKYNREDIETSVRECNKLKEDGMLFTKDVYENVIEEFSNNRQTVVKALCLHIA
                     HDCNLACRYCFAEEGEYHGRRALMSYEVGKKALDFLIANSGSRKNLEVDFFGGEPLMNW
                     QVVKDLVKYGREQEKLHNKKFRFTLTTNGVLLNDEVMEFCNKEMGNVVLSVDGRKEVHD
                     YMRPFRKGAGSYDLIMPKFQKFAESRNQDKYYVRGTFTHHNLDFSKDVLHLADLGFKQI
                     SVEPVVAADTEEYAIREEDIPQIMEEYDTLAKEMIKREKEGKGFNFFHFMIDLTGGPCV
                     YKRLSGCGSGTEYLAVTPWGDFYPCHQFVGEEQYLMGNVDEGITKPEIQKEFGGCNVYT
                     KKDCKDCFARFYCSGGCAANAFHFQGDIKGNYEIGCELQRKRVECAIMIKAALACD"
     CDS             complement(8612..8752)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg366_6"
                     /sec_met_domain="TIGR03973 (E-value: 1.9e-28, bitscore:
                     87.3, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 2.4e-28, bitscore: 87.0,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHIKTLNTKNLQNTVKKGGCGECQTSCQSACKTSCTVGNQSCEQ
                     K"
     CDS             complement(8826..9176)
                     /locus_tag="ctg366_7"
                     /transl_table=11
                     /translation="MKVRAILKSLLFAYALTGVALLLLALVLFAFDLGETAVDAGIIII
                     YVLACFMGGFMAGKIVRKDKYLWGVITGLAYYVLLLTVSVMAKGGWDMSAAHAVTTFFM
                     CTGGGTLGGMLS"
     CDS             complement(9226..10734)
                     /locus_tag="ctg366_8"
                     /transl_table=11
                     /translation="MSNNINRIRKNKLKGTGIFAAAALTAALIAGNNIPGVTRQVSAAE
                     SQENTVSSLIPDNITLDKPVELADVELPATEYGTFEWADGSFVPVQRVQSCEVLLIPAE
                     GQDLSHVDGWDPESGAVVGYINVIVNSITDGDNVDKTEGAGKTDPTENADPTETPETSS
                     EKPAAEENADTDNKEDKESKSDQDNKTDTDNEENKIEEDKTDNKNNKDNNSNADKTDKD
                     TETTGKLEPADDMTQDKEDTKKDDEDGADDNIFDNPVLPDDKDDRPTDAEDSLSDEEKE
                     ERAALNHTCDGITVSGVNLPWYVQFRVSSGDSYQFTNESDAMIFQSYEFELWDLKNNTE
                     YEIPNGDYISVTVPVKSGYQYTIEHLLDNGATETIIPSVENGIMVFSTHSFSPFGIAGS
                     RQLVGPDAGNDTDDTDAVTPAPASSDSQSSDSGKNNTVSMNDSSDSNNGSSSDQNDNST
                     ENKAVKNNNTVNTGDTTSIMPFVILFVAAAVIAGVAVFIKKRKK"
ORIGIN
        1 gaagccctgt acggttattt gcataaacct gaatctcagc catatacttc tctttttcct
       61 tggtatcagg ctgctgccac tctgcctcga tcagtcgggt cctgtctgtc tcagacatat
      121 tcagcacatt gacacaatct gtacgatgaa ttgtgatccc acgtcctctt gtaacaaaac
      181 ctacaatctc atcacccggg attggattac agcacttgga aaaacggact gccacatcat
      241 ggattccttt taccacaatg ccgctcttac tcttggcaat gtgaagcttt tcctgtgtct
      301 cagaagcagc ctcaagaacc tgctcatctg tcagattctt cttattttcc ttatcatatg
      361 cctccaccag cttattgaaa acctgacctt ctttcaatcc gccatgacca attgcagcaa
      421 gtactgaatc ccagtccctg aaaccatatt tacgcaaaac agcctccaga tactgggttt
      481 ttgtataatt tgcgatctta aatccctttg cacgcgcata ctgcgcaagc atctccttgc
      541 ccttaaggat attatcttct tttaattcct tcttgaacca ctggttaatc ttgttctttg
      601 cctgagtact cttaaccagt ttcagccagt cgcggcttgg tccctgagaa ttctgtgaag
      661 taatgatttc aatacggtcg ccgtttttga tctcatattc aatcggaacc agcttaccgt
      721 taactctggc acctaccatc ttatttccga ctgcactgtg aacactgtac gcaaaatcca
      781 ccggtgtaga accgcttgga agtgttttaa catctccctg tggagtgaaa cagtaaacac
      841 tgtccgcaaa aagatccagg tcattcttca gaagactcat gaattctttg ttatcagaca
      901 tgtctctctg ccattccaga atctgacgca gccagttcag tttctcttcc tcactcttac
      961 ctacaggagc ctttccgtca gacgactcct tatatttcca gtgtgcagcg ataccatatt
     1021 ctgcagttct gtgcatttca taagtacgga tctggatttc aaagggctgt ccgttgggtc
     1081 cgatcaatgt ggtatgcaat gactgataca tattgggttt cggcatggca atataatctt
     1141 taaaccgtcc cggaattggc ttatacatct catggatcac accaagggca gcataacaat
     1201 ccttcactgt atctacaaga atacggacag caaataaatc ataaatctga tcaatagtct
     1261 tatcctgatt taccatcttc ttgtagatgc tgaaaaagtg ttttacacgt ccgtccacct
     1321 gcgccttaat attggcatca tccatatgtt tcttaacttc ttttacaatc gcacctacaa
     1381 actgttctct ctcgctttta cgcagggcaa ccttatgcac caggtcataa tatacatccg
     1441 gcttaaggta tttcagcgac aggtcatcca gctctacctt tatcttggaa atacccagac
     1501 gcatggcaat aggagcataa atatccatgg tctctctggc cttttcctgc tgcttttcag
     1561 gacgcatata ctgtaaggta cgcatattat gaagacggtc tgcaagcttg atcagaataa
     1621 ctctgatatc cttagccatg gcaagaaaca tctttctgag gttctctgcc tgaacttcta
     1681 ctttatccgc agaataagat aactgtccca gcttggtaac accatccaca agaagtgcaa
     1741 cctctgaacc aaattccttc tccacttcct cataggtcat ccaggtatct tcaactgcat
     1801 catgaagaag acctgcaact atcgtttctt tgtcaagttc cagatctgcc agaatgatgg
     1861 caacacacaa aggatgaatg atatatggct ctccagactt tctcttctgt ccttcatgag
     1921 cttcacttgc aaccttatat gccttctcta tcatggaaat atctgttgat ggatgatact
     1981 tcagaacact gtttatcagt tctttataaa gcacctccgg acttgtaaaa tcatgcatgg
     2041 tctttactgc cgcatctgct ctctttacag attccagctt ctctttttca acctgcattt
     2101 catctttttt tgcttctgta ctttttgtta tctctgtcat atgctcccac ctgcctgtcc
     2161 tgcacaatca gctgtgccta tttaccatca taacaaatta cggacgctac atcataccca
     2221 ttcagtcttt cgcgtccctt taaacctgca agttccatga gaaatacaac cttgacaacc
     2281 tcaccgccaa gctgttccac cagcttgatc gctgcttcga tcgtaccgcc tgttgcgatc
     2341 agatcatcaa cgataaccac tttctgacct ggttttatgg aatctttatg catttcaatc
     2401 tctgcactgc catattccag atcatagctt acagatactg tttcgcgggg aagtttgcct
     2461 tttttacgaa tcggtacaaa tggtttatga agattatatg cgatcggtac accaaagata
     2521 aagcctctgg actctgttcc tgcaatcacg tccacatcta tatccttaag gcagtcctgc
     2581 atggagtcga tggccaactg caggccatcc gcatcctgca gaacacttgt aatatctctg
     2641 aaaataatcc ccggttcagg aaaatccggt atacttaata cataatcttc aattttcttc
     2701 attttatttc tcctccagtg tgtgttatat tgctgttcgc tcataaatat tttatagtat
     2761 atcacctttt tatttcagaa tcaagttact gttaagccct gacatttgta tttccaggct
     2821 taccggcggt tacaaaccaa gcggtaatat taacagtaat tctgaataat gatctgaaga
     2881 ctctctcgtc ccctgaatct gttgatctcc ggataataag taacagaaat actgtctttt
     2941 tccctgataa agttcacaaa atcctctgct tctccgaaat aaatgccttc cactgaaatc
     3001 ccctgcggat cgagaagttt taattttact acatttttat ttttcccgat aatactgtga
     3061 tcaagcactc tgagattttt ctgcgcaaag accggttttg tattcccttt tccaaagggc
     3121 tccaaaagcg aaatctgttc taccagttct tttgtaatat aagacacagg catcggcacg
     3181 tcaatcacga tcttaggacg caattcttcg tccgtcaacg tacagttgac attgagacgt
     3241 ctccggaatt cttctatatt tttttcttct atagaaagac ctgctgccat cggatgacct
     3301 ccaaactgta tcatcaggtc tgcacatttt accagttctt catacataga gtaactttct
     3361 attgatcttc cgcttccttt tgcacttgtc tcaccgcccg tcaatacaaa ggcaggcctg
     3421 tgatattttt ccctgatcct gcctgctata ataccggcaa gactttcatg acaatccgga
     3481 agataaacta ccagtactct gtcatttttc agctctgtag tctctatgat ccggattgcc
     3541 tcttcttttc ctttctcagt gagagctttt cggctctgat taagagctgt aagatctccg
     3601 gcaagccttg ctgcttcttc ctttgttttt gcattgagaa gtgcaagaga acgggcagct
     3661 gtgtccagtc tgccactggc attgatacat ggtcccagca caaatccgat atgataagct
     3721 gtgattttag catcttccag agaatttgct cggatcagtt cctgcaatcc ttgatttttg
     3781 gtatttttca gacggtacag tccttctttt accagaatcc tgttctctcc ctgaagatcc
     3841 ataacatctc ctactgttgc aatagccgcc agttcataat aatcttccag ctcctctgcc
     3901 ggaacaccaa atctctcgta aagtgctgca atatatttaa aggccaccac tgccccacac
     3961 aggtttttat tcgggtatgg acaatcatat tgtttcggat tcaaaatcgc atctgccggc
     4021 ggaagcacca tctggcgttc tcccttttcc tccctgtaag gaacctcatg atgatctgta
     4081 ataatcactg tcattccctt atcctttgcc atctggattt cagcagccgc agcaattcca
     4141 ttatcacagg tcacgatcgt atcgatccgg tccgtttccg ctctttctat aagatgtgca
     4201 tgaatcccat atccgtctgc aactctgtcc ggaatataag tatccacatc tgctccgatc
     4261 ctcgcaaggc ctttcattaa aatgtatgta gaggtcacac catcaatatc ataatcacca
     4321 ataatacgga cttttgcttt ctgcgatatt tttttctcca ggatatctac agctttttcc
     4381 atatccttca tcagccaggg agaaggaagc tcttgtactg ttcctgacag atactctctt
     4441 atcttatctt ctccgatcac atctctgttc ctgatcagtc tcgcaatcac cggatcaata
     4501 tgaaactgtt gaccgatctg gttaaaatct gctctttttg ctgctattac ccatttctcc
     4561 atatattttc tctcctcata aaaatatccc ggagttttac cccgggatat ttctgtctgc
     4621 ctgtttttca gacaattatt gttttattca gcatcatcat tctgctgttt tttagctgct
     4681 tcttcggcag ccagccgttc agctactctt tttctgtttt tcttctttgg ctgagtcgga
     4741 tctttctgtg atacatcacg tgctttcttc ggctttgaag aggactttgc agatgcggaa
     4801 gctgcagcaa ttgccggctg tccttttcct gcaaatttct ttttcatcac ataccacaac
     4861 gcacctgtaa tacatacaga agaatatgca ccgacaagaa caccaaccat cagaggtgct
     4921 gcaaattcac ggatagaaga aacacccatg atataaagaa cagctaccat aacaaaagtt
     4981 gtaaaagagg tataaatact tcttgtaaga gtctgagtga tacttgtgtt tacaatttct
     5041 gccagttttt ctctggaacc actgtgaagg ttctcacgta tacggtcaaa aataacgatt
     5101 gtagcattga tagaataacc tacgatcgta agcatgcagg caataaatgt attaccgaca
     5161 gatactctgg caatagcata gaatgcaagt acaaccagaa catcatgcag aagcgccaat
     5221 accgcactgc ttgcaaaacg gatgtcttta aatctgaacc agatataaag aagcatacag
     5281 attgtagcta ctataacggc tacgatcgca tcacgacgca tttcactact tactgtagaa
     5341 gaaatacttt ctgtggaaat cgtgctgtca tctacaccaa atttctcaac cagtgcactc
     5401 tgcagagctt cacgttcgct ctgattcaga gaacgtgtct tgatcacaac ctgatttgtt
     5461 ccgactacct ttgtaggctg aacattttta tctcctgtca cctcttctac aacaggagtt
     5521 acttcagaat caatggtctt aatatccata tcttcattaa atgtaacagt tgtagaagta
     5581 ccgcctgaga actcaaggct gtaatttaac gctttgtttc ctgcctgcga attagcaaac
     5641 atcgctgccg gcccgcagag gatcaggata atggaaatag caaaaaatac tttcttcttt
     5701 ccaaggaaat caactgcctt acgttctttt gcagatccgt agaatttcgg atcacgtaca
     5761 ccaactgcat aaagtgcatt tacaatcagt ctggatacaa ccagtgctgt aaacatggag
     5821 atcacgatac caagggcaag tgtataagca aatcccttaa cagtacctga accaagccac
     5881 atcagcacaa aggctgcgat cagtgttgta atatttccat caaagattgc agagaaagct
     5941 ttgctgaaac cggacttaat agaattcctt actgaaactc ctgcaccaat ttcctctctg
     6001 attcgggcat aaataataac attggcatcc accgccatac cgataccaag gataataccc
     6061 gcaatacccg gaagagtaag agtaatatca aaggcattca gcgtgatcag cattaatgat
     6121 gtataaagaa tcagtgcgat acctgcaact acaccaggta cgcggtatgc aatgatcata
     6181 aagataataa cgatgatcag accgatcgca cctgcaagaa cacttgtaga gattgcttct
     6241 tcaccaagct gtgcagctac aacactggaa cgaagttctt ccagttccag tcccagagaa
     6301 ccgatacgga tataagaagc aaggttctgt gcttcttcca ggtcagacat tccgctgatc
     6361 tgtgcttttc cgccggaaat ctcttcattt acattcggag cactgataat gttattgtca
     6421 tagacgatag cgatctgctt gcctacatta ttctttgtag cttctgcaaa ttttgtttta
     6481 ccactgtttt ctccatcaga agtaagagta agacttacca catattcctt tgcacttgtg
     6541 ttctgattct ggatcgcacc accctgggca tctgctacat cagaaccttc cagaacaaca
     6601 cttccggatt ccttgatctc atccatagtt ctggagagaa catatccatc ctgtcctgta
     6661 gtaaagttct ggtttccgtc agcatcttct tttgtgatga aatacaggga acctggttta
     6721 cccagatcat tcaaaatagt atctgcatct gtaacaccag gaatttcaac tgtaatacgg
     6781 tctgatcctt cctggtatac ctgagcctca gtactgtact gctctacacg cttctgaagc
     6841 ttgtagatcg tatctgacat ctcttcgctt gtcggattgc tttccttagc ctggtaggta
     6901 atgctgacac caccggcaag atcaagaccc gtgttgatat gttttgctgc accggttccg
     6961 gtaggaccga tacctacggc tgcagtaaag caaaagaaca cagtcaggat cagtgtcaga
     7021 agcagcacta cgattccttt acttttcttc atagttcttt tcccttcttg attttttgtc
     7081 cgcggtcatg ttcatccgcc tgccagccat tttctgttat gataacagcc gacggcggta
     7141 tcagtcagac agattactgc ccactaatca catgccagtg cggcttttat catgatggcg
     7201 cactccacac gttttctctg gagttcgcat ccgatttcat aattgccttt gatatctccc
     7261 tggaaatgga atgcatttgc cgcacatccg ccactacagt agaaacgtgc gaagcagtct
     7321 ttgcagtctt tctttgtgta aacgttgcat ccgccgaatt ccttctggat ttccggcttt
     7381 gtgatgcctt cgtctacatt tcccatgaga tactgttctt caccaacaaa ctggtgacat
     7441 gggtaaaaat caccccaggg tgttacagcc aggtactctg ttcctgaacc gcagcctgac
     7501 agtctcttgt atacacaagg gccacctgta aggtcgatca taaaatggaa gaagttaaat
     7561 ccttttccct ctttctctct tttaatcatt tcttttgcaa gagtatcata ctcttccatg
     7621 atctggggga tatcctcctc gcggatcgca tattcctccg tatcagccgc aactacaggc
     7681 tctacagaaa tctgtttgaa tccaagatct gccagatgaa gcacatcctt ggagaaatca
     7741 agattatggt gggtaaaagt acctcttaca taatacttgt cctgatttct ggattctgca
     7801 aacttctgga acttcggcat gatcaggtca tagcttcctg caccttttct gaatggacgc
     7861 atgtaatcat gtacttcctt acgtccgtcc acactcagta caacgttgcc catctcttta
     7921 ttgcagaatt ccattacttc atcattcaga agaactccgt ttgtcgttaa agtgaaacgg
     7981 aatttcttat tgtgaagctt ttcctgctct ctgccatatt ttaccagatc ttttacaacc
     8041 tgccagttca tcagcggctc gccgccaaag aaatctactt ccaggttttt tctggaaccg
     8101 gagttcgcga tcaggaaatc aagagctttt ttgccgactt cataggacat aagagctctt
     8161 ctgccatgat attcgccttc ttcggcaaaa caataacggc aggccagatt gcagtcatga
     8221 gcaatgtgca ggcacaatgc ttttacaacg gtctgccggt tatttgaaaa ttcttcaatt
     8281 acattctcat aaacatcttt tgtaaaaagc attccatctt ctttcagctt attacattct
     8341 cttacagatg tctcaatatc ttctctgtta tatttgtttt ccagtttctc tgcaatagct
     8401 tctgtgccaa ggccctcttc cagatatgga agaacctcat atgtaacctc atctaccaga
     8461 tggatgcatc cactgttgat atccagtaca atattaaagc cattgctttt ataacggtga
     8521 atcagactca ttttactaaa atcctttcta agcgtaagat aagcagcgga ataaaagttc
     8581 cgctgcttat ctcatttctc catagctgat cttatttctg ctcgcagctc tggtttccta
     8641 ctgtacagga agttttacat gcggactggc aggaagtctg gcactcgcca catccacctt
     8701 tttttacagt gttctgtaaa ttctttgtat tcagggtttt gatatgttcc ataactctat
     8761 cctccttatg taattatatt cttggcatag tatatcatat atcttctcat tttaaaagct
     8821 tttttttacg acagcattcc acccagtgtt ccaccgcctg tgcacataaa aaatgttgta
     8881 actgcatgag ctgcactcat atcccagccg ccttttgcca taacagagac agtcaacagt
     8941 aatacatagt aagccagacc tgtgataaca ccccacagat atttgtcttt acgcacaatt
     9001 ttgccggcca taaagcctcc catgaaacat gcaagtacat aaattataat aatccccgca
     9061 tctacagctg tttctcccag atcaaaagca aacagtacca gggccaaaag cagtaatgcc
     9121 actcctgtta atgcatatgc aaataatagt gatttcaaaa ttgctctgac tttcattgct
     9181 tcccctcctg ttaaactata tgggggagga atcagtgtta ttcttttatt tctttctctt
     9241 ttttataaat acagccacac cggcgatcac tgcagctgcc acaaacagta tcacaaacgg
     9301 cataattgat gttgtatctc cggtatttac tgtattgtta tttttcacag ctttattttc
     9361 cgttgaatta tcattctgat cagaagaaga accattattg ctgtcagaac tgtcattcat
     9421 agatactgta ttgttctttc cggaatcaga actctgactg tcggaggaag ccggtgcagg
     9481 agttaccgca tctgtgtcgt ccgtatcatt ccccgcatca ggtcctacta attgtctgct
     9541 tcctgcaatt ccaaatggac tgaaagaatg tgtgctgaat accataatac cattctctac
     9601 actcggaata atcgtctcag ttgccccgtt gtccaggaga tgttcgatag tatactgata
     9661 tccggatttt accggcacag tgacactgat ataatctcca ttagggatct catattctgt
     9721 attattctta agatcccaga gttcaaattc atatgactgg aaaatcattg catctgattc
     9781 attggtaaac tgatagctgt caccgcttga aactctgaac tgtacatacc atggaagatt
     9841 aactccactt actgtaatac cgtcgcaggt atgattaagt gcagccctct cttctttttc
     9901 ttcatcagaa agagaatcct ctgcatctgt aggacggtca tccttatcgt ccggcagaac
     9961 aggattatca aagatattat catctgcgcc atcttcatca tctttcttcg tatcttcttt
    10021 atcctgtgtc atatcatctg caggttccag cttaccggta gtttctgtat ctttatccgt
    10081 cttatctgca ttgctgttat tatctttgtt gtttttatta tctgttttat cttcttcaat
    10141 cttattctct tcattgtctg tatcagtttt attatcctga tctgatttac tttccttatc
    10201 ttctttattg tctgtatcag cgttttcttc tgcggcaggt ttttctgacg aagtttcagg
    10261 cgtttctgtt ggatctgcat tttcggttgg atctgtttta cctgcgcctt ctgtcttatc
    10321 aacattatca ccatccgtaa tactgttcac tattacattg atgtaaccga caaccgcgcc
    10381 gctctccgga tcccatccat ccacatggct taaatcctgc ccttcggccg gtataagaag
    10441 tacctcacag ctctgtacac gttgtacagg aacgaaactt ccatctgccc attcaaaagt
    10501 tccatattcc gttgccggaa gttctacatc cgcaagttct acaggcttat caagcgtgat
    10561 gttgtccgga atcagagaag acacagtatt ctcctgtgac tcagccgcac tgacctgtct
    10621 tgttacaccc ggtatattat ttcctgcaat caaagccgct gttaaagccg ctgccgcaaa
    10681 aatacccgtt ccttttaatt tattttttct tattctattt atattattgg acatatcgca
    10741 cctctatatt tatattcgat tcttatgttt cctgataatc atttttttac tttcagccaa
    10801 atatcagttc tctttttacg taatac
//
