LOCUS       c00075_gnlPro..        15196 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FPNDBBIJ_75.
ACCESSION   c00075_gnlPro..
VERSION     c00075_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 01:20:15
            Original ID  :: gnl|Prokka|FPNDBBIJ_75
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15196
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15196
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[184:5196]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      185..5196
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15196
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15196
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             185..1501
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_1"
                     /sec_met_domain="SLBB (E-value: 1.6e-17, bitscore: 54.0,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.7e-49, bitscore:
                     158.4, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 4.2e-42, bitscore: 133.1,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.3e-05, bitscore: 14.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGILTFKGGVHPYDGKELSKNSPVVKYLPKGDMVYPLSQHIGAPA
                     AAIVQKGDHVLAGQKIADAAGFVSSPIHSSVSGTVKGIEPRLTATGSMVNSIIIENDQQ
                     YESVEFTPARLEDLSKEEILARIKEGGVVGMGGAGFPTHVKLAPKEPDKIDHILVNGAE
                     CEPYLTSDYRRMLDDSEKLIEGLRVMLKLFDNAKGYICIEDNKPDCIAKLKEMVKDIPR
                     IEVAELMTKYPQGGERFLIKAVTDREINSAMLPADAGCVVDNVDTVIAVYEAVILGKPV
                     MDRIVTVTGQGIKNPQNFDVLSGTDMAELIEAAGGLTDNVSKVISGGPMMGFAMYDTHV
                     PCIKTSSACLCLEKDDVADAEQTACINCGRCVGVCPGHVIPARLATFAEHGDMKSFQKF
                     DGMECCECGCCSYICPAKRPLTQMIKSMRKMVLASRKKK"
     CDS             1517..2494
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_2"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 9.1e-121,
                     bitscore: 393.4, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQMLHVSSNPHVRDKMTTSKIMQLVALALLPTTLFGIYNFGLRA
                     LLVVVITVASSVFFEWIYDKLMHKKNTITDFSAVVTGLLLALNMPASIPLWMPVLGSAF
                     AIIVVKQLFGGLGQNFMNPALAGRCFLMISFAGKMTDFAVSDSFRGVVDTVSGATPLAA
                     LKQNGFTDSSVSVLHMFIGDIQGTIGETSALAILIGAAILLVFKVIDLKIPLTYIGSFA
                     VFVILYMLGTGKGFDVNYLFSHIFGGGLMLGAWFMATDYVTTPITPRGQYVYGVCLGVL
                     TAVFRLFGGSAEGVSYAIIFCNLLVPMIERVTRHPAFGKGGKKA"
     CDS             2491..3099
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_3"
                     /sec_met_domain="FMN_bind (E-value: 1.9e-20, bitscore:
                     64.1, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNRIIKDTIAITVITLVAGLALGVVQDITADPIAKQEAQAKQDA
                     YKAVFADADSFETVDVDADAMQSYLDENGYAAQSIDETMLAKDASGNELGYAFTVTTSE
                     GYGGDIQFAMGIQDDGTLNGISILSIGETAGLGMRANTDAFKDQFKDKNVDKFEYTKTG
                     ATADDQIDALSGATITTNAMTNGVNAGLCAFQYEKGGNQ"
     CDS             3099..3809
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_4"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.3e-72, bitscore:
                     232.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPNTPAERLYNGIIKENPTFVLMLGMCPTLAITTSATNGIGMGL
                     TTTVILAASNLMISLLRNFIPDRVRMPAFIVVVASFVTVVQLLLQGFIPSLYDSLGIYI
                     PLIVVNCIILGRAEAYASKNKPIASLFDGIGMGLGFTLSITCIGAVRELIGAGSLFGHQ
                     ILPLADAAAGKAGYEPITIFILAPGAFFVLAALSALQNKFKIGAAKRGIDPSNPDCGGS
                     CAACGNTMCKGKRG"
     CDS             3816..4391
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_5"
                     /sec_met_domain="Rnf-Nqr (E-value: 7.4e-63, bitscore:
                     202.5, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKELLIILVSSAIVNNVVLSQFLGLCPFLGVSKSVETAAGMGGAI
                     IFVITLSSFVTGIIYNAILVPTNLTYLQTIVFILLIAALVQFVEMFLKKTMPSLYQALG
                     VYLPLITTNCAVLGVALTNVQKEYNVLQGTVNGFATAVGFTISIVLMAGIREKIAYNDI
                     PKSFQGFPTVLLTAGLMAIAFFGFSGLI"
     CDS             4405..5196
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1020:4Fe-4S binding domain (Score: 31.8; E-value:
                     2.7e-10)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_6"
                     /sec_met_domain="Fer4_7 (E-value: 1.6e-10, bitscore: 32.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 8.1e-08, bitscore: 22.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 2.6e-16, bitscore: 49.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.2e-05, bitscore: 15.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIGAIIAATVLVAAVGLFIGVFLGVAGKKFAVEVDEKEVAVREA
                     LPGNNCGGCGYPGCDGLAAAIAKGEAPVNGCPVGGEPVGKVIAAIMGQEVVETTRQVAY
                     VKCAGTCEKTKDNYEYTGVEDCEMMAFIPGGGAKSCTYGCLGFGSCVKACPFGAIDVVN
                     GVAVVDKEACKACGKCVAKCPKHLIELVPYEQTTFVQCSSHAKGKAVTSACEVGCIGCK
                     KCEKTCPNGAITVDNFCAHIDYSKCTNCGACKEVCPRHIIQ"
     CDS             5345..5953
                     /locus_tag="ctg75_7"
                     /transl_table=11
                     /translation="MIAFVHGMAVDMTESSVVVEAGGIGYEIYMTGADLSEIRMGEDVK
                     VHTYFSVREDAMKLYGFRAKDDLQMFKLLLGVNGVGPKAALGVLAGITADELRFAILSD
                     DVKTLSKAPGIGKKTAQKLILELKDKMKLEDAFEFKLAHEQERAAVGAGGVSDGRQEAV
                     EALVALGYSSADALRAVRKVTDVPPDDVEGLLKAALKNF"
     CDS             6033..7037
                     /locus_tag="ctg75_8"
                     /transl_table=11
                     /translation="MEKRIITTDVTEEDFSLEGNLRPQTLDDYIGQEKTKSTLKVYIEA
                     AKQRHDALDHVLFYGPPGLGKTTLSGIIANEMGVHMKVTSGPAIEKPGEMAAILNNLQE
                     GDILFVDEIHRLNRQVEEVLYPAMEDYAIDIMIGKGASARSIRLDLPKFTLVGATTRAG
                     LLSAPLRDRFGVMHHLEFYTHEELKTIIIRSAQVLGVEIDEKGAAEIAKRSRGTPRLAN
                     RLLKRVRDFAQVKYDGRITYDVACFALNLLEVDQYGLDKIDRRILQTMIVNFQGGPVGL
                     ETLAAAIGEDSGTLEDVYEPYLLQNGFLNRTPRGRMASALAYEHLGYQMPEKN"
     CDS             7172..7579
                     /locus_tag="ctg75_9"
                     /transl_table=11
                     /translation="MAVKNTAKVIIGGKIITLGGYESEEYFQKVASYINKKMDELSAMP
                     GYSRQPMETKHTLISLNITDDYFKAKKQAEVFEQDLQQKDQEMYDLKHELISLRMQIEE
                     AQKHEQEALEQKSLLEGKNKELEKQIDELLK"
     CDS             7708..9903
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_10"
                     /sec_met_domain="Peptidase_U32 (E-value: 2.3e-82, bitscore:
                     266.4, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRREEIELLAPAGSYEGFEAAIGAGADAVYVGGAAFGARAYAKNF
                     GEEELLRAIDTAHIHGRKLYLTVNTLLKNRELSEQLYDYLLPYYKEGMDAVIVQDMGVF
                     KMIREMFPGMHLHASTQMTVTGPEGMKFLEEQGASRVVTARELSLEEIRRMHETSPIEI
                     ESFIHGALCYSYSGQCLMSSILGGRSGNRGRCAQPCRLPYQTALCCGENGRRSEKRKAQ
                     ELCPLSLKDISTIEILPQILEAGVTSLKIEGRMKQPGYTAGVTSVYRKYLDLLFEKGAE
                     NYRVAEEDKRYLLDLFNRGGSCTGYYQMQNGPSMMAFSNEKKTGDVSPVLRKKKEKIQG
                     TFILFPGSPAILDVSCRGIHGFASVGEVQYAQNQPLTEERIRSQMEKLGNTEYEWENLE
                     IQMDENIFIPMKMLNEARREALESLENELLKPYKREKNNGKKRLSEDAGRKADSLKQKN
                     LPIYISCEEKSTALALYKREGIHGMYLNADAMEVCLDDCVSRGMEMYLSLPHIMRGEMP
                     RELLTRIREWMDRGMTGFLVRNLETFAVLRKAGLAEKCVLDHSMYTWNDEAADFWKEQK
                     VLRNTVPLELNEGEIRHRDNRDSEMLIYGYLPLMISAQCVHKNLYGCNHKEEGVTLKDR
                     YDKEFTAKCICNPWKTENTDFCIPCYNIIYNSIPYGLLKEKSQIDRLGVSSLRLAFTIE
                     KPQDAVKIYEEFRAVYRDGKNPPKREYTKGHFKRGAE"
     CDS             9909..11282
                     /locus_tag="ctg75_11"
                     /transl_table=11
                     /translation="MINVIVELSKYVILTLMVIYTFHCFYLVKQQSEEERNESLRQQLM
                     LIFFMDFTAFLVIYLKTGKFQVVLFYIEMMAFFAGIQILYRIFYKKASILLLNNMCMLL
                     SVGFIMLCRLDVSTATRQLVIVAGVNVVALIVPVLIRKMKFLKDLTWVYAGIGIVLLAA
                     VFVLAKTSYGAKLSLMGIQPSEAIKITFVFFMAALLRKGADFSKVIQATVVAGLHVGIL
                     VLSRDLGSAVIFFAAYLVMIYVASRNVGYLALGLAGGSAGAVVAYHLFGHVRQRVTAWK
                     DPMAVYQNEGYQIVQSLFAIGTGGWFGMGLCQGSPEKIPVVKNDFIFSAICEELGGIFA
                     ICLILVCMSFFLMIVNIALKIKKPFYKLIALGLGTEYAFQVFLTIGGATKFIPMTGVTL
                     PLVSYGGSSVACTVLMLAIIQGLYILREDEDEEIERYRRKGTAQRVEEAPEAQSTGDF"
     CDS             11242..12693
                     /locus_tag="ctg75_12"
                     /transl_table=11
                     /translation="LKKRQKRKAREISEKRRPRNREYTLVSCFFVLIFVSMIGYLIYFN
                     YAKSDDFINSPYNTRQDTFSDRVVRGKIISADGQVLAQTNVYEDGTEERTYPYANMFAH
                     VVGYDTNGKSGLESEANFQLLTSHEFFLNQMKNEFKNQKNTGDSVITTLNADLQSTAYN
                     ALGDRRGAVVAIEPSTGKILVEMSRPDFDPNTISQNWDTLVNDSNDSSLLNRATNGAYP
                     PGSTFKVVTALDYFRTKGSLEGFSYLCEGSITREDHTIRCYGGTVHGQEDFYSAFANSC
                     NSAFAEIGTMLGGSSLKKTAEDLLFNKSLPLSSYKKSTFTLNGKSSVAEVMQTAIGQGN
                     TLVSPMHMALITSAIANGGELMKPYLIDSVVSSDGETVKTTEPESYKRLMTTNESNILG
                     KLMKGVVENGTASALNGRGYTVAGKTGSAEFDENGSSHSWFIGYSNVDDPDLVVAIIVE
                     NGGTGSEAAVPIAEQIFDAYYYDKQ"
     CDS             12874..13329
                     /locus_tag="ctg75_13"
                     /transl_table=11
                     /translation="MIEATSCGGVVIHRGKILTLYKSYRNRYEGWVLPKGTVEPGETHE
                     QTALREVMEEAGVRATIVKYIGKSQYNFTVPEDVVSKEVHWYLMTADNYHSKPQREEFF
                     VDSGYYKFHEIYHLLRFSNEKQIVERAYQEYLEMRSNGLWGKQHKYY"
     CDS             13434..13745
                     /locus_tag="ctg75_14"
                     /transl_table=11
                     /translation="MLKWQENFLAGESVKDPEKIKKKLNSGKPVLGIYLLTLSENPVNL
                     MDIIPAAMLIQKSFYGICPKIIGMAKGKEEALEMVRSLIDEMYRETGTFATAEYIENR"
     CDS             13750..14778
                     /locus_tag="ctg75_15"
                     /transl_table=11
                     /translation="MLHILWLILKFILIILGILLGLLLLAVLLVLFCPVRYKASAVKAE
                     GGWKQTEGEGIVSWLFHGISLRAEWKDQQMEISFHLFGIPVDKLLKKRKEKRDITKKSG
                     KNPEKSGAEKVSVSGIDGNREEEHKKSVVDHPKSENMETEDLKTDRNSASDTSADTERI
                     RNSQISGQQELNADDTDRNSLKKRQFFIKRIYDRIRNIFQSIRTKLQNIRRTFGKIKKN
                     VSWWKAFIEHPRVTAARKLVWKHGKFLLKHIFPTRIEGQVTFSFEDPALTGAALAVLGM
                     TIPFHKNCIQINPRFDSENYLYGNIRAKGRIYGFVPVRAAVSIYFNKNIKYVIKRWKTR
                     RA"
     CDS             14781..15152
                     /locus_tag="ctg75_16"
                     /transl_table=11
                     /translation="MANENNFKETVNSLFKGMDSFISAKTVVGEAIHVGDTIILPLMDV
                     SFGVGAGAFSGEKKDNGGGGMAGKMTPCAVLVIQNGTTKLVNVKNQDGLTKILDMVPDF
                     VDRFTSGKGDEESVGESEK"
ORIGIN
        1 gttaataatt tttcctttct gaaattgttt ttaattatac acaagaaaat gaaatttggg
       61 tagtgctttt tttgaaaaaa tggtttatat tataaacagg ttgataaaaa tgtacaaaaa
      121 agtatatgga ttttatcaaa aatagagcac tttggtggtg cttaatataa aaggagggaa
      181 cgaaatggga attttaacct ttaagggtgg tgttcatcct tatgacggaa aagaattatc
      241 caagaacagt ccggtagtga aatatctgcc aaagggagat atggtatatc ctctttccca
      301 gcatatcggt gctccggctg cagcgatagt tcagaaggga gaccatgtgc tcgcaggaca
      361 gaagatcgca gatgctgcgg ggtttgtctc atcaccgatc cattcgtctg tttccggtac
      421 ggtaaaagga atcgaaccgc gcctgacagc aacaggttct atggtcaatt ccattatcat
      481 tgagaatgac cagcagtatg aaagtgtgga atttactcct gcacgtctgg aagatctttc
      541 gaaagaggag attttggcga gaattaaaga aggcggagta gtgggaatgg gtggcgccgg
      601 attccccaca catgtaaagc ttgcgccaaa ggaaccggac aagatcgatc atatccttgt
      661 aaacggtgcc gagtgtgaac cctatcttac cagtgactac agaagaatgc tggatgactc
      721 tgagaagctg atcgagggct taagagttat gctgaagctc tttgacaatg cgaagggata
      781 tatctgtatt gaggataaca agcctgactg tattgcgaaa ctgaaagaaa tggtaaaaga
      841 tattccacgt attgaagtag cagagctgat gaccaagtac ccacagggtg gtgagcgttt
      901 cctgatcaag gctgtcacag acagagagat caactctgcc atgcttccgg cagatgcagg
      961 atgcgtagtt gacaacgtag ataccgtaat tgctgtttat gaagccgtta tccttggaaa
     1021 acctgttatg gaccgtatcg tgacagtaac aggacagggg attaagaatc cgcagaactt
     1081 tgatgttctt tccggaacag atatggcaga gcttatagaa gctgccggcg gactgacaga
     1141 caatgtatcc aaagtaattt caggtggtcc tatgatggga tttgccatgt atgacactca
     1201 tgtaccatgt attaagacaa gctccgcatg tctctgcctg gagaaggatg atgtggcaga
     1261 tgccgaacag actgcatgca ttaactgcgg cagatgtgta ggagtctgtc ccggccatgt
     1321 cattcctgca agacttgcaa cctttgcaga gcatggtgac atgaagagct tccagaaatt
     1381 tgatggtatg gagtgctgcg aatgtggctg ctgcagttat atctgccctg ccaaacgtcc
     1441 gctgacccag atgatcaaat ctatgcgtaa gatggttctg gcaagccgta agaaaaagta
     1501 aaagggggac atcgtaatgg atcagatgtt acatgtatca tccaatcccc atgtccggga
     1561 taagatgaca acaagcaaaa tcatgcagct tgtggcactg gcgcttctgc cgaccacact
     1621 gtttggaatt tataattttg gccttcgcgc cttactggta gtagtgatca ccgtcgcttc
     1681 cagtgtattc tttgagtgga tttatgacaa gctgatgcat aagaagaaca caattacaga
     1741 cttcagtgca gttgttacag gtttattact tgcattaaat atgcctgcat caattccgct
     1801 ctggatgcct gtacttggca gtgcatttgc gatcatcgtt gtaaaacagc tcttcggtgg
     1861 tctgggacag aacttcatga acccggcact tgcaggaaga tgtttcctga tgatctcttt
     1921 cgcaggaaag atgacagatt tcgcagtaag cgacagcttc agaggtgtgg tagatactgt
     1981 atccggtgca actcctctgg cagctctgaa acagaatgga tttacagaca gttctgtatc
     2041 tgtattacat atgtttatcg gtgatatcca gggaactatc ggtgagactt ctgcccttgc
     2101 gatcctgatc ggagcagcaa tccttctggt tttcaaggtg atcgatctga agattccgct
     2161 tacctatatt ggaagtttcg cagtatttgt aatcctttac atgcttggaa caggcaaggg
     2221 atttgacgtg aactatctgt tcagccacat cttcggcggt ggtcttatgc ttggtgcatg
     2281 gtttatggct acagactatg tcacaacacc gatcacacca agaggacagt atgtatacgg
     2341 tgtctgtctt ggtgtactga ctgcggtctt ccgtctcttc ggcggttccg cagagggcgt
     2401 atcctatgcg atcattttct gcaacctgtt agttccgatg atcgaacgtg tgactcgtca
     2461 cccggcattt gggaaagggg gcaaaaaggc atgagtaaca gaattatcaa agataccata
     2521 gccattacag tgatcacact ggtggcagga cttgcccttg gtgtagtcca ggatattacg
     2581 gcagatccta ttgcaaagca ggaagcacag gcgaaacagg atgcgtataa ggcagtattt
     2641 gcagatgcgg acagctttga gacagtggat gtggatgcgg atgccatgca gtcttatctg
     2701 gatgagaacg gatatgcagc acagtccata gatgagacta tgcttgccaa ggatgcttca
     2761 ggcaatgaac tgggatatgc atttacagta accacttccg agggttacgg cggagatatc
     2821 cagtttgcaa tgggtatcca ggatgacggt accttaaatg gaatttccat tctttctatc
     2881 ggtgagaccg caggtcttgg tatgagagca aacacagatg catttaagga tcagttcaaa
     2941 gataagaacg tagacaaatt tgaatataca aagaccggtg ccacagcgga tgatcagatc
     3001 gatgcgttaa gtggtgccac tattacaacg aatgccatga caaacggtgt taatgccgga
     3061 ttatgtgcat tccagtatga gaaaggggga aatcagtgat gaaaccaaac acacctgctg
     3121 aacgtttata taacggaatc atcaaagaaa atcctacctt tgtactgatg cttggtatgt
     3181 gtcctacact ggctatcacc acatctgcaa ccaatggtat cggaatggga cttactacaa
     3241 cagtgatcct tgcagcatcc aacttaatga tctctcttct gagaaacttt attccggaca
     3301 gagtgcgtat gcctgcattt atcgtagttg ttgcttcctt tgtaacagtt gtacagcttc
     3361 ttttacaggg atttatccca agtctgtatg actcccttgg aatctatatt cctctgatcg
     3421 tggttaactg tatcatcctt ggacgtgcag aagcatatgc atccaagaat aaaccgattg
     3481 cctctctgtt tgatggtatt ggtatgggtc ttggatttac cttaagtatc acctgtatcg
     3541 gtgcagtacg tgagctgatc ggcgcaggtt ctctgttcgg acatcagatc cttcctctgg
     3601 cagatgctgc agcaggtaag gctggttatg aaccgatcac aatctttatc ctggcacccg
     3661 gagcattctt tgttctggca gcgctttctg cattacagaa caaattcaaa atcggtgcag
     3721 ccaaacgtgg cattgatcca agtaatcctg attgcggcgg aagctgtgca gcctgtggca
     3781 ataccatgtg taagggaaaa agggggtaat ggattatgaa agaacttttg atcatacttg
     3841 taagctcagc gattgtaaat aacgtagtcc tcagccagtt ccttggcctc tgtcctttcc
     3901 ttggtgtttc caagagtgtt gagacagcag ccggcatggg cggtgcgatc atcttcgtta
     3961 ttacactgtc atcttttgtg acaggtatta tttacaatgc tatcctggtt cctacgaacc
     4021 tgacttatct gcagactatc gtattcatcc tgctgatcgc ggcgctggta cagtttgtag
     4081 agatgtttct taagaagaca atgccttccc tgtatcaggc acttggtgtg tatcttccac
     4141 tgatcacaac aaactgtgcg gttcttggcg ttgcccttac aaacgtgcag aaagagtata
     4201 atgttcttca gggaacagtg aacggatttg caacagcagt gggctttact atttccatcg
     4261 tgctgatggc tggtatccgt gagaaaatcg catacaatga cattccaaaa tccttccagg
     4321 gattccctac agttctgctg acagccggac tgatggcaat tgccttcttc ggattttcag
     4381 gactgattta aggaggggac tggtatgaat ataggagcaa ttatcgcggc aactgtactg
     4441 gttgcggcag taggcctttt tatcggtgtt ttccttggcg ttgccggtaa gaagtttgct
     4501 gtggaagtgg atgagaagga agttgctgtt cgtgaggcgc ttcccggtaa taactgcggt
     4561 ggctgtggtt atcccggctg tgatggtctg gcagcagcga tcgccaaagg tgaggcacct
     4621 gtaaatggat gtccggtagg cggtgagcct gtcggaaaag taatcgcagc gatcatggga
     4681 caggaagttg tggagactac ccgtcaggtg gcgtatgtga agtgtgcggg tacctgtgag
     4741 aagacgaagg ataattatga gtatacaggt gtggaagact gtgagatgat ggctttcatt
     4801 cccggtggcg gtgcgaagtc ctgtacttat ggatgccttg gttttggaag ctgcgtgaag
     4861 gcctgtccgt ttggggcgat tgatgttgtg aacggtgtgg cggttgttga taaggaggct
     4921 tgtaaggcct gcggtaagtg tgttgccaag tgtccgaagc atctgatcga gcttgtgccc
     4981 tatgagcaga ctacgtttgt gcagtgtagt tctcatgcga aaggtaaggc tgttacttct
     5041 gcgtgtgagg ttggctgtat cggatgtaag aagtgtgaga agacttgccc gaatggggcg
     5101 attacggttg ataatttctg tgcgcatatt gattatagta agtgtacgaa ttgtggggct
     5161 tgtaaagagg tttgtccgag acatattatt cagtaatggg agaaagaact gctgtgtgaa
     5221 ggcatggcgg ttcttttttt tcgattaagg cgcgcgaaca atatacgcga atatatgttt
     5281 gcgttatgag gtggtatgtg gtatgatgaa tcggaagtga tgaatttggg acggaggatg
     5341 tatcatgatt gcgtttgttc atggaatggc tgtggatatg actgagagct cggtggttgt
     5401 tgaggccggg gggattggtt atgagatata tatgacgggg gcagatttgt ctgagattcg
     5461 tatgggggag gatgtgaagg tccatactta ttttagtgtg agagaggatg ccatgaagct
     5521 gtatgggttt agggctaagg atgatctgca gatgtttaag ctgcttcttg gcgtgaatgg
     5581 tgtggggccg aaggctgcgc tgggggttct ggcggggatt acggcggatg aattgaggtt
     5641 tgcaattctt tcggatgatg tgaagacgtt gtcgaaggct ccgggtatcg ggaagaagac
     5701 ggctcagaag ctgattcttg agctgaagga taagatgaag ctggaggatg cgtttgaatt
     5761 taagctggct catgagcagg agagggcagc agtgggagcc ggtggggttt cggatggcag
     5821 gcaggaagct gttgaggctc tggttgcgct gggatacagc agtgcggatg cgcttcgtgc
     5881 ggtgcgtaag gttacggatg tgccgccgga tgatgtggaa ggtcttttga aggctgcact
     5941 gaagaatttt taactgaagc aggactttac gctctggtag attggattgc ctgtattgtt
     6001 atagaattgt tataggttag gatgggtaac agatggagaa acgtattata actacggatg
     6061 tgacggagga ggatttttct ctggagggga atctccggcc gcagacgttg gatgattata
     6121 ttggtcagga gaagaccaag agtactttga aggtttatat agaggctgcg aagcagaggc
     6181 atgatgcatt ggatcatgtt ttgttttatg gtcctccggg gcttggtaag actactcttt
     6241 cggggattat tgccaatgag atgggggttc atatgaaggt gacttccggg ccggctattg
     6301 agaagccggg ggagatggct gcgatcctta ataatctgca ggagggagat attctgtttg
     6361 tggatgagat ccaccgcctg aacaggcagg tggaggaggt cctttatcct gctatggagg
     6421 attatgctat tgatattatg atcgggaagg gagcttctgc caggtctata cgtctggatc
     6481 tgccgaagtt tacactggtg ggggcgacta ccagggcagg acttttgtct gcacctcttc
     6541 gtgaccgttt tggtgtgatg catcatctgg agttttatac tcatgaggag cttaagacga
     6601 tcatcatccg ttctgctcag gttcttggag tggagattga tgagaagggt gcggctgaga
     6661 ttgccaagag atccagggga actccgaggc ttgccaaccg tctgctgaag agggttcgtg
     6721 attttgcgca ggtgaagtat gatggacgga ttacttatga tgtggcgtgt tttgcgctga
     6781 atcttctgga agtggatcag tatggtctgg ataagattga cagaaggatt cttcagacta
     6841 tgatcgtgaa ttttcagggt ggtcctgtgg gactggagac tctggctgcg gcgatagggg
     6901 aggattccgg tacgctggag gatgtgtatg agccttatct gctgcagaat ggattcctga
     6961 accgtacgcc gagaggacgt atggcatcgg cgcttgcgta tgagcatctg ggctatcaga
     7021 tgccggagaa aaactgaagt taagggcgta aaaatataaa aaagtaaaag ttttttaaaa
     7081 attcctatac atttcgactg ctttcgagta taatgaagta aatgtccggg gttccgggca
     7141 gattgaagga agatacagga ggctcgtacg gatggcggtc aaaaatacag caaaggtaat
     7201 cataggtggt aagattatta cgctgggagg ctatgaatcg gaagaatatt ttcagaaagt
     7261 agcatcctat ataaataaaa agatggatga gttaagtgct atgccgggtt acagcagaca
     7321 gcccatggag accaagcata cacttatcag cctgaatatt acagatgact attttaaggc
     7381 aaagaaacag gcggaggttt ttgaacagga tttacagcag aaggatcagg agatgtatga
     7441 tctgaagcat gagctgatct cgcttcgtat gcagattgag gaagcgcaga agcatgaaca
     7501 ggaagccctg gaacagaaga gccttctgga gggaaagaat aaggaactgg aaaagcagat
     7561 tgatgagctg ctgaaataac agagggggga ttacttcggt gatttcccct ttatgatttg
     7621 tttcatatgt attcgatttg aatattatag caatgctcat aaataatgca tttaagatga
     7681 ctgttataga aaacgtgagg tatagaattg agaagagaag agattgaact tctggcacct
     7741 gccggttcct atgagggatt tgaggcagcg atcggtgcag gtgcagatgc ggtttatgta
     7801 gggggagcag cctttggcgc gcgggcctat gcgaagaatt tcggagagga agagcttttg
     7861 cgtgccattg atactgctca tatccatggc aggaaacttt atctgacagt gaatacgctg
     7921 ttgaagaaca gggaactgtc tgaacagttg tatgattatc tgcttccata ttataaggaa
     7981 ggtatggatg cggtgatcgt tcaggatatg ggtgtgttta agatgatcag ggagatgttt
     8041 ccgggtatgc atcttcatgc cagcacgcag atgactgtga caggtccgga ggggatgaag
     8101 tttctggaag aacagggtgc ttccagagtg gtaactgcca gagaactttc ccttgaggaa
     8161 atccggagga tgcatgagac aagtcctatc gagattgaat cttttatcca tggagcttta
     8221 tgttacagtt attcgggaca gtgcctgatg agcagtatcc tgggtggaag aagcggtaac
     8281 agaggaaggt gtgcacagcc ttgccgtctg ccttaccaga cagcgctttg ttgcggggaa
     8341 aatggcagac ggtcagagaa aaggaaagcg caagaactat gtcctctgag tctgaaggat
     8401 atttctacga tagagattct tccgcagatt ctggaggctg gtgttacttc tcttaagata
     8461 gagggcagga tgaagcagcc gggatataca gcaggggtaa cttctgtata tcggaagtac
     8521 ctggatcttc tttttgagaa gggagctgag aattacaggg tagcagagga ggataagaga
     8581 tatctgctgg atctgtttaa caggggaggt tcctgtaccg gttattatca gatgcagaat
     8641 ggtccgtcca tgatggcatt cagcaatgag aagaaaacag gagatgtcag tcctgtatta
     8701 agaaaaaaga aagaaaaaat tcagggaaca ttcattcttt ttccgggaag tcctgctata
     8761 ctggatgtgt catgcagggg aatccatgga tttgcgtctg tgggtgaggt acagtatgcg
     8821 cagaaccagc cgctgacaga ggagcgcatc cgttcacaga tggagaagct tggaaataca
     8881 gaatatgagt gggaaaatct ggaaatccag atggatgaga atatttttat cccgatgaaa
     8941 atgctgaatg aggcgagaag agaggcactg gaatctctgg aaaatgaatt gctcaaacca
     9001 tataagagag aaaaaaataa tgggaagaaa cgcttatcag aggatgccgg aagaaaagca
     9061 gattcgctaa agcagaaaaa tcttccgatt tatatttcct gtgaagaaaa atccactgca
     9121 ctggcgttat ataaaagaga ggggatacat ggaatgtatc tgaacgctga tgccatggag
     9181 gtctgcctgg atgactgtgt aagcagagga atggagatgt atctgtctct tccgcatatt
     9241 atgagaggtg agatgccccg ggagcttctc accaggatca gagagtggat ggacagagga
     9301 atgacaggat ttctggtaag aaatctggag acttttgcag ttctgcgaaa ggcaggtctg
     9361 gctgagaaat gtgttctgga tcacagtatg tatacatgga atgatgaagc tgctgatttc
     9421 tggaaagagc agaaagtcct cagaaatacg gtaccgcttg agctgaacga aggggaaatc
     9481 cgccacagag ataaccggga cagcgagatg ctgatctacg gatatctgcc tcttatgata
     9541 tcggcccagt gtgtgcataa aaatctttac ggatgtaatc ataaggaaga aggggtaact
     9601 ttaaaagacc gttacgataa agaatttacg gcgaaatgta tatgtaaccc atggaaaact
     9661 gagaatacag atttctgtat accctgctat aatatcattt acaacagtat cccttacggc
     9721 ctgttgaaag agaaatcaca gatagacaga cttggtgtct cttccctgag acttgcattt
     9781 accattgaga agcctcagga tgcggtgaag atatatgaag agttcagagc tgtttatcgt
     9841 gatgggaaga atcctccgaa acgggaatat acaaagggac attttaaaag aggagccgag
     9901 taaggcatat gattaatgta attgtagaat tatccaagta tgtgatcctt accctgatgg
     9961 tgatttatac ctttcactgt ttctatctgg tgaaacagca gagtgaggag gagagaaacg
    10021 aatcgctgcg ccagcagctg atgcttatct tttttatgga tttcactgcg tttctggtca
    10081 tctacctgaa gacaggtaag tttcaggtcg tgttgtttta tatcgaaatg atggcatttt
    10141 ttgcgggaat ccagattttg tacaggattt tttataagaa agcatcgatt ttactgctca
    10201 acaatatgtg catgcttctc agcgtaggat ttattatgct gtgcagactg gatgtttcca
    10261 cagctaccag acagctggtg atcgtggcag gcgtaaatgt ggtggcattg atcgtacctg
    10321 tcctgatcag gaagatgaaa tttctcaagg acctgacatg ggtttatgcg ggaatcggaa
    10381 tcgttttgct ggcggcggta tttgtgcttg caaagacaag ctatggagca aaactttcct
    10441 tgatgggaat ccagccttca gaggcgataa agattacatt tgtgttcttt atggcggcat
    10501 tgctgagaaa aggtgctgat ttttcaaaag tgatccaggc tacggtagtg gcgggactgc
    10561 atgtggggat tcttgtactt tccagagacc ttggaagtgc agtgatcttc tttgcggcat
    10621 atcttgtgat gatttatgtg gcatccagaa atgtgggata tctggcactt ggtcttgcag
    10681 gcggatctgc aggggcagtt gtcgcatatc atctgtttgg ccatgtgcgt cagagagtga
    10741 cagcctggaa ggatcccatg gcggtatatc agaatgaagg ataccagatc gtccagtcac
    10801 tgtttgccat tggaaccggc ggatggtttg gaatgggatt gtgtcagggt tcgcctgaga
    10861 agatccctgt tgtcaagaat gactttatat tcagtgcaat ctgtgaggaa ctgggtggga
    10921 tttttgcaat ctgcctgatc ctggtatgta tgagtttctt tttgatgatc gtaaatattg
    10981 cgcttaagat taagaaacca ttctacaaac tgatcgcact tggacttggt acggaatatg
    11041 catttcaggt atttctgaca attggcggag caacgaaatt tatccctatg acaggtgtaa
    11101 ctcttcctct ggtcagctat ggaggaagtt ctgtcgcgtg tacagtactg atgctggcga
    11161 tcattcaggg attgtatatt ttgagagaag atgaggacga agaaattgag agatatcgaa
    11221 gaaaaggaac ggcgcagaga gttgaagaag cgccagaagc gcaaagcacg ggagatttct
    11281 gaaaagagaa ggccccgtaa cagagagtat acactggtat cctgcttttt tgtgctgatc
    11341 tttgtcagta tgatcggata tctgatctac tttaattatg caaagagcga tgattttatc
    11401 aatagtccct ataatacaag gcaggatact ttttcagaca gggttgtaag aggtaagatc
    11461 atatctgcag atgggcaggt gcttgcccag accaatgttt acgaagacgg aacagaggaa
    11521 cgtacttatc cctatgcaaa tatgttcgct catgtagtcg gatatgacac taatggaaaa
    11581 agcggactgg aatcagaggc gaacttccag cttctgactt ctcatgaatt tttcctgaac
    11641 cagatgaaaa atgagtttaa gaatcagaaa aatacgggtg attctgtgat cacgacgtta
    11701 aacgcagatc ttcagtcaac tgcctataat gcacttggtg acaggagagg ggcggttgtt
    11761 gccatagaac cctctacagg taagattctg gtggaaatga gcagaccgga ctttgacccg
    11821 aatactattt cccagaactg ggacacactg gtgaatgatt ccaatgacag cagtctgttg
    11881 aacagagcta caaacggagc ctatcctccg ggatctacat ttaaggtggt aactgccctg
    11941 gactatttca gaaccaaggg cagtctggag ggattttcct atctctgtga gggaagtatt
    12001 accagagaag atcacacgat caggtgctat ggcggaactg ttcatggaca ggaagatttt
    12061 tacagtgctt ttgccaattc ctgtaacagt gcatttgcag agatcggaac catgctcgga
    12121 ggcagttctc tgaaaaaaac agccgaggat cttcttttta ataagagtct tccgctttct
    12181 tcctataaaa agagtacttt tacattaaat ggaaaatctt ctgttgcaga ggttatgcag
    12241 actgccatcg gacagggtaa tacgttggta tcacctatgc atatggcgct gattaccagt
    12301 gcaatcgcca atggcgggga gctcatgaag ccttatctca ttgattctgt tgtaagttca
    12361 gacggagaga cagtgaagac aacagagccg gagagctata aacgtctgat gacaacaaat
    12421 gagtcgaata tccttggaaa gcttatgaaa ggtgttgtgg aaaacggaac cgcatcggct
    12481 ctgaacggaa gaggatatac agtggcaggc aagaccggat cagcggaatt tgatgagaat
    12541 ggttccagtc attcctggtt tatcggttat tccaacgtgg atgatccgga tctggtagtt
    12601 gcgatcattg ttgagaatgg cggtaccgga agtgaagcag cagtgcccat cgcagagcag
    12661 atatttgatg cgtattatta tgataagcaa taataaattc catgttgcag gcaatcggga
    12721 atgaatcttg actacgttac tgtgaacgca gttaaaatta actaattaat cgttaatatg
    12781 ttatgaaatg atatttatag cttgcgggtt tggaaaaaaa gagatatact atactcagtt
    12841 tataatacca cgcaaaacag gagggattgc attatgatag aagcaacgag ctgtggcggt
    12901 gtggtaattc atcggggtaa gattcttact ttgtataaat cttacaggaa ccgttatgag
    12961 ggctgggtat tgccgaaagg aacagtggaa ccaggcgaaa cgcatgaaca gacagcattg
    13021 cgggaagtga tggaagaggc tggagtgcgt gcgaccattg tgaaatacat cggaaagagc
    13081 caatataact ttaccgttcc ggaggacgtg gtttccaaag aggtacactg gtatcttatg
    13141 actgcggata attatcatag taagccccag agagaggagt tttttgtaga ttccggatat
    13201 tataaatttc atgagatcta tcatctgctg aggttttcaa acgagaagca gatcgtagag
    13261 cgtgcttatc aggaatatct ggagatgaga agcaatggac tctggggaaa acagcataag
    13321 tattattaac gagagaacag ggctgtgttt ttttgcaacg cagcccggtt taaattttgg
    13381 agaaaatgga aatactgtaa ctgaagtgtt atagaaacgg gagagggtgt aagatgctga
    13441 aatggcagga gaattttctt gcaggggaat ctgtaaagga tcctgagaag ataaaaaaga
    13501 aactgaacag cggaaaaccg gttctgggca tttatctcct tactctgtca gagaatcctg
    13561 tgaatctgat ggatattatt cctgcagcaa tgctgataca gaagagcttt tatggaatct
    13621 gtccgaagat cataggaatg gcgaagggca aagaggaagc cctggagatg gtgcgaagtc
    13681 tgatcgatga aatgtacagg gaaacgggaa ccttcgcaac agctgaatat atagaaaaca
    13741 ggtgagaata tgttacatat tttatggctg atccttaaat ttatactgat catcctggga
    13801 attctgctgg gccttctttt actggcagtt cttcttgtac tgttctgtcc tgtaagatat
    13861 aaggcatcag ctgtcaaggc agaaggtggc tggaaacaga cagagggaga gggtatcgta
    13921 agctggctgt ttcatgggat ttcgctgaga gcggaatgga aagatcagca gatggagata
    13981 tcctttcatc tgtttggaat tcccgtagac aagttgttga aaaaacggaa ggagaagagg
    14041 gatataacaa agaaatccgg gaaaaatccg gagaaatccg gcgcagaaaa ggtatctgta
    14101 tccggcatag acggaaacag ggaagaagag cataaaaaat cagtggttga tcacccgaaa
    14161 tcagagaata tggagactga ggatctgaaa acagacagaa attcagcttc agatacatct
    14221 gctgatacag agaggatcag aaacagtcag atatccggac agcaggaact gaatgcagat
    14281 gatacagatc ggaatagtct aaagaagagg cagtttttta taaaaaggat ctatgaccgg
    14341 atccgaaata tatttcagtc gattcgtaca aaactgcaaa atatccgcag gacattcggg
    14401 aagattaaga agaatgtgtc ctggtggaag gcgtttatag aacatcccag agtgacagct
    14461 gccagaaagc ttgtatggaa acatggaaaa tttttgctta agcatatttt tcctacaagg
    14521 atagaagggc aggttacttt ttcttttgaa gatccggcgc tgacaggtgc ggcacttgct
    14581 gtacttggga tgacaattcc atttcacaaa aactgtatac agatcaatcc ccgttttgac
    14641 agtgagaatt atctatatgg aaacatcagg gcaaaaggca ggatctacgg atttgttcct
    14701 gtgcgggcag cagtgagtat ttatttcaat aaaaatataa aatacgttat aaaacgttgg
    14761 aaaaccagga gggcatgacc atggcaaatg aaaacaattt taaagaaacc gtaaattcat
    14821 tattcaaggg aatggacagt tttatttctg cgaaaacagt ggtaggagag gcaatccatg
    14881 taggcgatac gatcattctt cctctgatgg atgtatcttt cggtgtaggt gccggtgctt
    14941 tttcaggaga gaagaaggat aacggcggcg gcggaatggc aggaaagatg actccctgtg
    15001 cagtgcttgt gatccagaat ggaacaacaa agctggtcaa tgtgaaaaat caggatggtc
    15061 tcaccaagat ccttgatatg gttccggatt ttgtagatcg ttttacctcc ggaaaaggtg
    15121 acgaagaatc tgtcggcgaa tcagaaaaat aatttttgca tagactatag caaaccgatg
    15181 aaaaaggtgc agaaga
//
