LOCUS       c00121_gnlPro..        15092 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NODIPJOO_121.
ACCESSION   c00121_gnlPro..
VERSION     c00121_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 01:32:02
            Original ID  :: gnl|Prokka|NODIPJOO_121
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15092
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15092
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[80:5092]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      81..5092
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15092
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15092
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             81..1397
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_1"
                     /sec_met_domain="SLBB (E-value: 1.7e-17, bitscore: 54.0,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.9e-49, bitscore:
                     158.4, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 4.5e-42, bitscore: 133.1,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.9e-05, bitscore: 14.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGILTFKGGVHPYDGKELSKNSPVVKYLPKGDMVYPLSQHIGAPA
                     AAIVQKGDHVLAGQKIADAAGFVSSPIHSSVSGTVKGIEPRLTATGSMVNSIIIENDQQ
                     YESVEFTPARLEDLSKEEILARIKEGGVVGMGGAGFPTHVKLAPKEPDKIDHILVNGAE
                     CEPYLTSDYRRMLDDSEKLIEGLRVMLKLFDNAKGYICIEDNKPDCIAKLKEMVKDIPR
                     IEVAELMTKYPQGGERFLIKAVTDREINSAMLPADAGCVVDNVDTVIAVYEAVILGKPV
                     MDRIVTVTGQGIKNPQNFDVLSGTDMAELIEAAGGLTDNVSKVISGGPMMGFAMYDTHV
                     PCIKTSSACLCLEKDDVADAEQTACINCGRCVGVCPGHVIPARLATFAEHGDMKSFQKF
                     DGMECCECGCCSYICPAKRPLTQMIKSMRKMVLASRKKK"
     CDS             1413..2390
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_2"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 9.8e-121,
                     bitscore: 393.4, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQMLHVSSNPHVRDKMTTSKIMQLVALALLPTTLFGIYNFGLRA
                     LLVVVITVASSVFFEWIYDKLMHKKNTITDFSAVVTGLLLALNMPASIPLWMPVLGSAF
                     AIIVVKQLFGGLGQNFMNPALAGRCFLMISFAGKMTDFAVSDSFRGVVDTVSGATPLAA
                     LKQNGFTDSSVSVLHMFIGDIQGTIGETSALAILIGAAILLVFKVIDLKIPLTYIGSFA
                     VFVILYMLGTGKGFDVNYLFSHIFGGGLMLGAWFMATDYVTTPITPRGQYVYGVCLGVL
                     TAVFRLFGGSAEGVSYAIIFCNLLVPMIERVTRHPAFGKGGKKA"
     CDS             2387..2995
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_3"
                     /sec_met_domain="FMN_bind (E-value: 2.1e-20, bitscore:
                     64.1, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNRIIKDTIAITVITLVAGLALGVVQDITADPIAKQEAQAKQDA
                     YKAVFADADSFETVDVDADAMQSYLDENGYAAQSIDETMLAKDASGNELGYAFTVTTSE
                     GYGGDIQFAMGIQDDGTLNGISILSIGETAGLGMRANTDAFKDQFKDKNVDKFEYTKTG
                     ATADDQIDALSGATITTNAMTNGVNAGLCAFQYEKGGNQ"
     CDS             2995..3705
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_4"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.5e-72, bitscore:
                     232.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPNTPAERLYNGIIKENPTFVLMLGMCPTLAITTSATNGIGMGL
                     TTTVILAASNLMISLLRNFIPDRVRMPAFIVVVASFVTVVQLLLQGFIPSLYDSLGIYI
                     PLIVVNCIILGRAEAYASKNKPIASLFDGIGMGLGFTLSITCIGAVRELIGAGSLFGHQ
                     ILPLADAAAGKAGYEPITIFILAPGAFFVLAALSALQNKFKIGAAKRGIDPSNPDCGGS
                     CAACGNTMCKGKRG"
     CDS             3712..4287
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_5"
                     /sec_met_domain="Rnf-Nqr (E-value: 7.9e-63, bitscore:
                     202.5, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKELLIILVSSAIVNNVVLSQFLGLCPFLGVSKSVETAAGMGGAI
                     IFVITLSSFVTGIIYNAILVPTNLTYLQTIVFILLIAALVQFVEMFLKKTMPSLYQALG
                     VYLPLITTNCAVLGVALTNVQKEYNVLQGTVNGFATAVGFTISIVLMAGIREKIAYNDI
                     PKSFQGFPTVLLTAGLMAIAFFGFSGLI"
     CDS             4301..5092
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1020:4Fe-4S binding domain (Score: 31.8; E-value:
                     2.7e-10)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_6"
                     /sec_met_domain="Fer4_7 (E-value: 1.8e-10, bitscore: 32.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 8.7e-08, bitscore: 22.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 2.8e-16, bitscore: 49.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.5e-05, bitscore: 15.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIGAIIAATVLVAAVGLFIGVFLGVAGKKFAVEVDEKEVAVREA
                     LPGNNCGGCGYPGCDGLAAAIAKGEAPVNGCPVGGEPVGKVIAAIMGQEVVETTRQVAY
                     VKCAGTCEKTKDNYEYTGVEDCEMMAFIPGGGAKSCTYGCLGFGSCVKACPFGAIDVVN
                     GVAVVDKEACKACGKCVAKCPKHLIELVPYEQTTFVQCSSHAKGKAVTSACEVGCIGCK
                     KCEKTCPNGAITVDNFCAHIDYSKCTNCGACKEVCPRHIIQ"
     CDS             5241..5849
                     /locus_tag="ctg121_7"
                     /transl_table=11
                     /translation="MIAFVHGMAVDMTESSVVVEAGGIGYEIYMTGADLSEIRMGEDVK
                     VHTYFSVREDAMKLYGFRAKDDLQMFKLLLGVNGVGPKAALGVLAGITADELRFAILSD
                     DVKTLSKAPGIGKKTAQKLILELKDKMKLEDAFEFKLAHEQERAAVGAGGVSDGRQEAV
                     EALVALGYSSADALRAVRKVTDVPPDDVEGLLKAALKNF"
     CDS             5929..6933
                     /locus_tag="ctg121_8"
                     /transl_table=11
                     /translation="MEKRIITTDVTEEDFSLEGNLRPQTLDDYIGQEKTKSTLKVYIEA
                     AKQRHDALDHVLFYGPPGLGKTTLSGIIANEMGVHMKVTSGPAIEKPGEMAAILNNLQE
                     GDILFVDEIHRLNRQVEEVLYPAMEDYAIDIMIGKGASARSIRLDLPKFTLVGATTRAG
                     LLSAPLRDRFGVMHHLEFYTHEELKTIIIRSAQVLGVEIDEKGAAEIAKRSRGTPRLAN
                     RLLKRVRDFAQVKYDGRITYDVACFALNLLEVDQYGLDKIDRRILQTMIVNFQGGPVGL
                     ETLAAAIGEDSGTLEDVYEPYLLQNGFLNRTPRGRMASALAYEHLGYQMPEKN"
     CDS             7068..7475
                     /locus_tag="ctg121_9"
                     /transl_table=11
                     /translation="MAVKNTAKVIIGGKIITLGGYESEEYFQKVASYINKKMDELSAMP
                     GYSRQPMETKHTLISLNITDDYFKAKKQAEVFEQDLQQKDQEMYDLKHELISLRMQIEE
                     AQKHEQEALEQKSLLEGKNKELEKQIDELLK"
     CDS             7604..9799
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg121_10"
                     /sec_met_domain="Peptidase_U32 (E-value: 2.4e-82, bitscore:
                     266.4, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRREEIELLAPAGSYEGFEAAIGAGADAVYVGGAAFGARAYAKNF
                     GEEELLRAIDTAHIHGRKLYLTVNTLLKNRELSEQLYDYLLPYYKEGMDAVIVQDMGVF
                     KMIREMFPGMHLHASTQMTVTGPEGMKFLEEQGASRVVTARELSLEEIRRMHETSPIEI
                     ESFIHGALCYSYSGQCLMSSILGGRSGNRGRCAQPCRLPYQTALCCGENGRRSEKRKAQ
                     ELCPLSLKDISTIEILPQILEAGVTSLKIEGRMKQPGYTAGVTSVYRKYLDLLFEKGAE
                     NYRVAEEDKRYLLDLFNRGGSCTGYYQMQNGPSMMAFSNEKKTGDVSPVLRKKKEKIQG
                     TFILFPGSPAILDVSCRGIHGFASVGEVQYAQNQPLTEERIRSQMEKLGNTEYEWENLE
                     IQMDENIFIPMKMLNEARREALESLENELLKPYKREKNNGKKRLSEDAGRKADSLKQKN
                     LPIYISCEEKSTALALYKREGIHGMYLNADAMEVCLDDCVSRGMEMYLSLPHIMRGEMP
                     RELLTRIREWMDRGMTGFLVRNLETFAVLRKAGLAEKCVLDHSMYTWNDEAADFWKEQK
                     VLRNTVPLELNEGEIRHRDNRDSEMLIYGYLPLMISAQCVHKNLYGCNHKEEGVTLKDR
                     YDKEFTAKCICNPWKTENTDFCIPCYNIIYNSIPYGLLKEKSQIDRLGVSSLRLAFTIE
                     KPQDAVKIYEEFRAVYRDGKNPPKREYTKGHFKRGAE"
     CDS             9805..11178
                     /locus_tag="ctg121_11"
                     /transl_table=11
                     /translation="MINVIVELSKYVILTLMVIYTFHCFYLVKQQSEEERNESLRQQLM
                     LIFFMDFTAFLVIYLKTGKFQVVLFYIEMMAFFAGIQILYRIFYKKASILLLNNMCMLL
                     SVGFIMLCRLDVSTATRQLVIVAGVNVVALIVPVLIRKMKFLKDLTWVYAGIGIVLLAA
                     VFVLAKTSYGAKLSLMGIQPSEAIKITFVFFMAALLRKGADFSKVIQATVVAGLHVGIL
                     VLSRDLGSAVIFFAAYLVMIYVASRNVGYLALGLAGGSAGAVVAYHLFGHVRQRVTAWK
                     DPMAVYQNEGYQIVQSLFAIGTGGWFGMGLCQGSPEKIPVVKNDFIFSAICEELGGIFA
                     ICLILVCMSFFLMIVNIALKIKKPFYKLIALGLGTEYAFQVFLTIGGATKFIPMTGVTL
                     PLVSYGGSSVACTVLMLAIIQGLYILREDEDEEIERYRRKGTAQRVEEAPEAQSTGDF"
     CDS             11138..12589
                     /locus_tag="ctg121_12"
                     /transl_table=11
                     /translation="LKKRQKRKAREISEKRRPRNREYTLVSCFFVLIFVSMIGYLIYFN
                     YAKSDDFINSPYNTRQDTFSDRVVRGKIISADGQVLAQTNVYEDGTEERTYPYANMFAH
                     VVGYDTNGKSGLESEANFQLLTSHEFFLNQMKNEFKNQKNTGDSVITTLNADLQSTAYN
                     ALGDRRGAVVAIEPSTGKILVEMSRPDFDPNTISQNWDTLVNDSNDSSLLNRATNGAYP
                     PGSTFKVVTALDYFRTKGSLEGFSYLCEGSITREDHTIRCYGGTVHGQEDFYSAFANSC
                     NSAFAEIGTMLGGSSLKKTAEDLLFNKSLPLSSYKKSTFTLNGKSSVAEVMQTAIGQGN
                     TLVSPMHMALITSAIANGGELMKPYLIDSVVSSDGETVKTTEPESYKRLMTTNESNILG
                     KLMKGVVENGTASALNGRGYTVAGKTGSAEFDENGSSHSWFIGYSNVDDPDLVVAIIVE
                     NGGTGSEAAVPIAEQIFDAYYYDKQ"
     CDS             12770..13225
                     /locus_tag="ctg121_13"
                     /transl_table=11
                     /translation="MIEATSCGGVVIHRGKILTLYKSYRNRYEGWVLPKGTVEPGETHE
                     QTALREVMEEAGVRATIVKYIGKSQYNFTVPEDVVSKEVHWYLMTADNYHSKPQREEFF
                     VDSGYYKFHEIYHLLRFSNEKQIVERAYQEYLEMRSNGLWGKQHKYY"
     CDS             13330..13641
                     /locus_tag="ctg121_14"
                     /transl_table=11
                     /translation="MLKWQENFLAGESVKDPEKIKKKLNSGKPVLGIYLLTLSENPVNL
                     MDIIPAAMLIQKSFYGICPKIIGMAKGKEEALEMVRSLIDEMYRETGTFATAEYIENR"
     CDS             13646..14674
                     /locus_tag="ctg121_15"
                     /transl_table=11
                     /translation="MLHILWLILKFILIILGILLGLLLLAVLLVLFCPVRYKASAVKAE
                     GGWKQTEGEGIVSWLFHGISLRAEWKDQQMEISFHLFGIPVDKLLKKRKEKRDITKKSG
                     KNPEKSGAEKVSVSGIDGNREEEHKKSVVDHPKSENMETEDLKTDRNSASDTSADTERI
                     RNSQISGQQELNADDTDRNSLKKRQFFIKRIYDRIRNIFQSIRTKLQNIRRTFGKIKKN
                     VSWWKAFIEHPRVTAARKLVWKHGKFLLKHIFPTRIEGQVTFSFEDPALTGAALAVLGM
                     TIPFHKNCIQINPRFDSENYLYGNIRAKGRIYGFVPVRAAVSIYFNKNIKYVIKRWKTR
                     RA"
     CDS             14677..15048
                     /locus_tag="ctg121_16"
                     /transl_table=11
                     /translation="MANENNFKETVNSLFKGMDSFISAKTVVGEAIHVGDTIILPLMDV
                     SFGVGAGAFSGEKKDNGGGGMAGKMTPCAVLVIQNGTTKLVNVKNQDGLTKILDMVPDF
                     VDRFTSGKGDEESVGESEK"
ORIGIN
        1 taaaaatgta caaaaaagta tatggatttt atcaaaaata gagcactttg gtggtgctta
       61 atataaaagg agggaacgaa atgggaattt taacctttaa gggtggtgtt catccttatg
      121 acggaaaaga attatccaag aacagtccgg tagtgaaata tctgccaaag ggagatatgg
      181 tatatcctct ttcccagcat atcggtgctc cggctgcagc gatagttcag aagggagacc
      241 atgtgctcgc aggacagaag atcgcagatg ctgcggggtt tgtctcatca ccgatccatt
      301 cgtctgtttc cggtacggta aaaggaatcg aaccgcgcct gacagcaaca ggttctatgg
      361 tcaattccat tatcattgag aatgaccagc agtatgaaag tgtggaattt actcctgcac
      421 gtctggaaga tctttcgaaa gaggagattt tggcgagaat taaagaaggc ggagtagtgg
      481 gaatgggtgg cgccggattc cccacacatg taaagcttgc gccaaaggaa ccggacaaga
      541 tcgatcatat ccttgtaaac ggtgccgagt gtgaacccta tcttaccagt gactacagaa
      601 gaatgctgga tgactctgag aagctgatcg agggcttaag agttatgctg aagctctttg
      661 acaatgcgaa gggatatatc tgtattgagg ataacaagcc tgactgtatt gcgaaactga
      721 aagaaatggt aaaagatatt ccacgtattg aagtagcaga gctgatgacc aagtacccac
      781 agggtggtga gcgtttcctg atcaaggctg tcacagacag agagatcaac tctgccatgc
      841 ttccggcaga tgcaggatgc gtagttgaca acgtagatac cgtaattgct gtttatgaag
      901 ccgttatcct tggaaaacct gttatggacc gtatcgtgac agtaacagga caggggatta
      961 agaatccgca gaactttgat gttctttccg gaacagatat ggcagagctt atagaagctg
     1021 ccggcggact gacagacaat gtatccaaag taatttcagg tggtcctatg atgggatttg
     1081 ccatgtatga cactcatgta ccatgtatta agacaagctc cgcatgtctc tgcctggaga
     1141 aggatgatgt ggcagatgcc gaacagactg catgcattaa ctgcggcaga tgtgtaggag
     1201 tctgtcccgg ccatgtcatt cctgcaagac ttgcaacctt tgcagagcat ggtgacatga
     1261 agagcttcca gaaatttgat ggtatggagt gctgcgaatg tggctgctgc agttatatct
     1321 gccctgccaa acgtccgctg acccagatga tcaaatctat gcgtaagatg gttctggcaa
     1381 gccgtaagaa aaagtaaaag ggggacatcg taatggatca gatgttacat gtatcatcca
     1441 atccccatgt ccgggataag atgacaacaa gcaaaatcat gcagcttgtg gcactggcgc
     1501 ttctgccgac cacactgttt ggaatttata attttggcct tcgcgcctta ctggtagtag
     1561 tgatcaccgt cgcttccagt gtattctttg agtggattta tgacaagctg atgcataaga
     1621 agaacacaat tacagacttc agtgcagttg ttacaggttt attacttgca ttaaatatgc
     1681 ctgcatcaat tccgctctgg atgcctgtac ttggcagtgc atttgcgatc atcgttgtaa
     1741 aacagctctt cggtggtctg ggacagaact tcatgaaccc ggcacttgca ggaagatgtt
     1801 tcctgatgat ctctttcgca ggaaagatga cagatttcgc agtaagcgac agcttcagag
     1861 gtgtggtaga tactgtatcc ggtgcaactc ctctggcagc tctgaaacag aatggattta
     1921 cagacagttc tgtatctgta ttacatatgt ttatcggtga tatccaggga actatcggtg
     1981 agacttctgc ccttgcgatc ctgatcggag cagcaatcct tctggttttc aaggtgatcg
     2041 atctgaagat tccgcttacc tatattggaa gtttcgcagt atttgtaatc ctttacatgc
     2101 ttggaacagg caagggattt gacgtgaact atctgttcag ccacatcttc ggcggtggtc
     2161 ttatgcttgg tgcatggttt atggctacag actatgtcac aacaccgatc acaccaagag
     2221 gacagtatgt atacggtgtc tgtcttggtg tactgactgc ggtcttccgt ctcttcggcg
     2281 gttccgcaga gggcgtatcc tatgcgatca ttttctgcaa cctgttagtt ccgatgatcg
     2341 aacgtgtgac tcgtcacccg gcatttggga aagggggcaa aaaggcatga gtaacagaat
     2401 tatcaaagat accatagcca ttacagtgat cacactggtg gcaggacttg cccttggtgt
     2461 agtccaggat attacggcag atcctattgc aaagcaggaa gcacaggcga aacaggatgc
     2521 gtataaggca gtatttgcag atgcggacag ctttgagaca gtggatgtgg atgcggatgc
     2581 catgcagtct tatctggatg agaacggata tgcagcacag tccatagatg agactatgct
     2641 tgccaaggat gcttcaggca atgaactggg atatgcattt acagtaacca cttccgaggg
     2701 ttacggcgga gatatccagt ttgcaatggg tatccaggat gacggtacct taaatggaat
     2761 ttccattctt tctatcggtg agaccgcagg tcttggtatg agagcaaaca cagatgcatt
     2821 taaggatcag ttcaaagata agaacgtaga caaatttgaa tatacaaaga ccggtgccac
     2881 agcggatgat cagatcgatg cgttaagtgg tgccactatt acaacgaatg ccatgacaaa
     2941 cggtgttaat gccggattat gtgcattcca gtatgagaaa gggggaaatc agtgatgaaa
     3001 ccaaacacac ctgctgaacg tttatataac ggaatcatca aagaaaatcc tacctttgta
     3061 ctgatgcttg gtatgtgtcc tacactggct atcaccacat ctgcaaccaa tggtatcgga
     3121 atgggactta ctacaacagt gatccttgca gcatccaact taatgatctc tcttctgaga
     3181 aactttattc cggacagagt gcgtatgcct gcatttatcg tagttgttgc ttcctttgta
     3241 acagttgtac agcttctttt acagggattt atcccaagtc tgtatgactc ccttggaatc
     3301 tatattcctc tgatcgtggt taactgtatc atccttggac gtgcagaagc atatgcatcc
     3361 aagaataaac cgattgcctc tctgtttgat ggtattggta tgggtcttgg atttacctta
     3421 agtatcacct gtatcggtgc agtacgtgag ctgatcggcg caggttctct gttcggacat
     3481 cagatccttc ctctggcaga tgctgcagca ggtaaggctg gttatgaacc gatcacaatc
     3541 tttatcctgg cacccggagc attctttgtt ctggcagcgc tttctgcatt acagaacaaa
     3601 ttcaaaatcg gtgcagccaa acgtggcatt gatccaagta atcctgattg cggcggaagc
     3661 tgtgcagcct gtggcaatac catgtgtaag ggaaaaaggg ggtaatggat tatgaaagaa
     3721 cttttgatca tacttgtaag ctcagcgatt gtaaataacg tagtcctcag ccagttcctt
     3781 ggcctctgtc ctttccttgg tgtttccaag agtgttgaga cagcagccgg catgggcggt
     3841 gcgatcatct tcgttattac actgtcatct tttgtgacag gtattattta caatgctatc
     3901 ctggttccta cgaacctgac ttatctgcag actatcgtat tcatcctgct gatcgcggcg
     3961 ctggtacagt ttgtagagat gtttcttaag aagacaatgc cttccctgta tcaggcactt
     4021 ggtgtgtatc ttccactgat cacaacaaac tgtgcggttc ttggcgttgc ccttacaaac
     4081 gtgcagaaag agtataatgt tcttcaggga acagtgaacg gatttgcaac agcagtgggc
     4141 tttactattt ccatcgtgct gatggctggt atccgtgaga aaatcgcata caatgacatt
     4201 ccaaaatcct tccagggatt ccctacagtt ctgctgacag ccggactgat ggcaattgcc
     4261 ttcttcggat tttcaggact gatttaagga ggggactggt atgaatatag gagcaattat
     4321 cgcggcaact gtactggttg cggcagtagg cctttttatc ggtgttttcc ttggcgttgc
     4381 cggtaagaag tttgctgtgg aagtggatga gaaggaagtt gctgttcgtg aggcgcttcc
     4441 cggtaataac tgcggtggct gtggttatcc cggctgtgat ggtctggcag cagcgatcgc
     4501 caaaggtgag gcacctgtaa atggatgtcc ggtaggcggt gagcctgtcg gaaaagtaat
     4561 cgcagcgatc atgggacagg aagttgtgga gactacccgt caggtggcgt atgtgaagtg
     4621 tgcgggtacc tgtgagaaga cgaaggataa ttatgagtat acaggtgtgg aagactgtga
     4681 gatgatggct ttcattcccg gtggcggtgc gaagtcctgt acttatggat gccttggttt
     4741 tggaagctgc gtgaaggcct gtccgtttgg ggcgattgat gttgtgaacg gtgtggcggt
     4801 tgttgataag gaggcttgta aggcctgcgg taagtgtgtt gccaagtgtc cgaagcatct
     4861 gatcgagctt gtgccctatg agcagactac gtttgtgcag tgtagttctc atgcgaaagg
     4921 taaggctgtt acttctgcgt gtgaggttgg ctgtatcgga tgtaagaagt gtgagaagac
     4981 ttgcccgaat ggggcgatta cggttgataa tttctgtgcg catattgatt atagtaagtg
     5041 tacgaattgt ggggcttgta aagaggtttg tccgagacat attattcagt aatgggagaa
     5101 agaactgctg tgtgaaggca tggcggttct tttttttcga ttaaggcgcg cgaacaatat
     5161 acgcgaatat atgtttgcgt tatgaggtgg tatgtggtat gatgaatcgg aagtgatgaa
     5221 tttgggacgg aggatgtatc atgattgcgt ttgttcatgg aatggctgtg gatatgactg
     5281 agagctcggt ggttgttgag gccgggggga ttggttatga gatatatatg acgggggcag
     5341 atttgtctga gattcgtatg ggggaggatg tgaaggtcca tacttatttt agtgtgagag
     5401 aggatgccat gaagctgtat gggtttaggg ctaaggatga tctgcagatg tttaagctgc
     5461 ttcttggcgt gaatggtgtg gggccgaagg ctgcgctggg ggttctggcg gggattacgg
     5521 cggatgaatt gaggtttgca attctttcgg atgatgtgaa gacgttgtcg aaggctccgg
     5581 gtatcgggaa gaagacggct cagaagctga ttcttgagct gaaggataag atgaagctgg
     5641 aggatgcgtt tgaatttaag ctggctcatg agcaggagag ggcagcagtg ggagccggtg
     5701 gggtttcgga tggcaggcag gaagctgttg aggctctggt tgcgctggga tacagcagtg
     5761 cggatgcgct tcgtgcggtg cgtaaggtta cggatgtgcc gccggatgat gtggaaggtc
     5821 ttttgaaggc tgcactgaag aatttttaac tgaagcagga ctttacgctc tggtagattg
     5881 gattgcctgt attgttatag aattgttata ggttaggatg ggtaacagat ggagaaacgt
     5941 attataacta cggatgtgac ggaggaggat ttttctctgg aggggaatct ccggccgcag
     6001 acgttggatg attatattgg tcaggagaag accaagagta ctttgaaggt ttatatagag
     6061 gctgcgaagc agaggcatga tgcattggat catgttttgt tttatggtcc tccggggctt
     6121 ggtaagacta ctctttcggg gattattgcc aatgagatgg gggttcatat gaaggtgact
     6181 tccgggccgg ctattgagaa gccgggggag atggctgcga tccttaataa tctgcaggag
     6241 ggagatattc tgtttgtgga tgagatccac cgcctgaaca ggcaggtgga ggaggtcctt
     6301 tatcctgcta tggaggatta tgctattgat attatgatcg ggaagggagc ttctgccagg
     6361 tctatacgtc tggatctgcc gaagtttaca ctggtggggg cgactaccag ggcaggactt
     6421 ttgtctgcac ctcttcgtga ccgttttggt gtgatgcatc atctggagtt ttatactcat
     6481 gaggagctta agacgatcat catccgttct gctcaggttc ttggagtgga gattgatgag
     6541 aagggtgcgg ctgagattgc caagagatcc aggggaactc cgaggcttgc caaccgtctg
     6601 ctgaagaggg ttcgtgattt tgcgcaggtg aagtatgatg gacggattac ttatgatgtg
     6661 gcgtgttttg cgctgaatct tctggaagtg gatcagtatg gtctggataa gattgacaga
     6721 aggattcttc agactatgat cgtgaatttt cagggtggtc ctgtgggact ggagactctg
     6781 gctgcggcga taggggagga ttccggtacg ctggaggatg tgtatgagcc ttatctgctg
     6841 cagaatggat tcctgaaccg tacgccgaga ggacgtatgg catcggcgct tgcgtatgag
     6901 catctgggct atcagatgcc ggagaaaaac tgaagttaag ggcgtaaaaa tataaaaaag
     6961 taaaagtttt ttaaaaattc ctatacattt cgactgcttt cgagtataat gaagtaaatg
     7021 tccggggttc cgggcagatt gaaggaagat acaggaggct cgtacggatg gcggtcaaaa
     7081 atacagcaaa ggtaatcata ggtggtaaga ttattacgct gggaggctat gaatcggaag
     7141 aatattttca gaaagtagca tcctatataa ataaaaagat ggatgagtta agtgctatgc
     7201 cgggttacag cagacagccc atggagacca agcatacact tatcagcctg aatattacag
     7261 atgactattt taaggcaaag aaacaggcgg aggtttttga acaggattta cagcagaagg
     7321 atcaggagat gtatgatctg aagcatgagc tgatctcgct tcgtatgcag attgaggaag
     7381 cgcagaagca tgaacaggaa gccctggaac agaagagcct tctggaggga aagaataagg
     7441 aactggaaaa gcagattgat gagctgctga aataacagag gggggattac ttcggtgatt
     7501 tcccctttat gatttgtttc atatgtattc gatttgaata ttatagcaat gctcataaat
     7561 aatgcattta agatgactgt tatagaaaac gtgaggtata gaattgagaa gagaagagat
     7621 tgaacttctg gcacctgccg gttcctatga gggatttgag gcagcgatcg gtgcaggtgc
     7681 agatgcggtt tatgtagggg gagcagcctt tggcgcgcgg gcctatgcga agaatttcgg
     7741 agaggaagag cttttgcgtg ccattgatac tgctcatatc catggcagga aactttatct
     7801 gacagtgaat acgctgttga agaacaggga actgtctgaa cagttgtatg attatctgct
     7861 tccatattat aaggaaggta tggatgcggt gatcgttcag gatatgggtg tgtttaagat
     7921 gatcagggag atgtttccgg gtatgcatct tcatgccagc acgcagatga ctgtgacagg
     7981 tccggagggg atgaagtttc tggaagaaca gggtgcttcc agagtggtaa ctgccagaga
     8041 actttccctt gaggaaatcc ggaggatgca tgagacaagt cctatcgaga ttgaatcttt
     8101 tatccatgga gctttatgtt acagttattc gggacagtgc ctgatgagca gtatcctggg
     8161 tggaagaagc ggtaacagag gaaggtgtgc acagccttgc cgtctgcctt accagacagc
     8221 gctttgttgc ggggaaaatg gcagacggtc agagaaaagg aaagcgcaag aactatgtcc
     8281 tctgagtctg aaggatattt ctacgataga gattcttccg cagattctgg aggctggtgt
     8341 tacttctctt aagatagagg gcaggatgaa gcagccggga tatacagcag gggtaacttc
     8401 tgtatatcgg aagtacctgg atcttctttt tgagaaggga gctgagaatt acagggtagc
     8461 agaggaggat aagagatatc tgctggatct gtttaacagg ggaggttcct gtaccggtta
     8521 ttatcagatg cagaatggtc cgtccatgat ggcattcagc aatgagaaga aaacaggaga
     8581 tgtcagtcct gtattaagaa aaaagaaaga aaaaattcag ggaacattca ttctttttcc
     8641 gggaagtcct gctatactgg atgtgtcatg caggggaatc catggatttg cgtctgtggg
     8701 tgaggtacag tatgcgcaga accagccgct gacagaggag cgcatccgtt cacagatgga
     8761 gaagcttgga aatacagaat atgagtggga aaatctggaa atccagatgg atgagaatat
     8821 ttttatcccg atgaaaatgc tgaatgaggc gagaagagag gcactggaat ctctggaaaa
     8881 tgaattgctc aaaccatata agagagaaaa aaataatggg aagaaacgct tatcagagga
     8941 tgccggaaga aaagcagatt cgctaaagca gaaaaatctt ccgatttata tttcctgtga
     9001 agaaaaatcc actgcactgg cgttatataa aagagagggg atacatggaa tgtatctgaa
     9061 cgctgatgcc atggaggtct gcctggatga ctgtgtaagc agaggaatgg agatgtatct
     9121 gtctcttccg catattatga gaggtgagat gccccgggag cttctcacca ggatcagaga
     9181 gtggatggac agaggaatga caggatttct ggtaagaaat ctggagactt ttgcagttct
     9241 gcgaaaggca ggtctggctg agaaatgtgt tctggatcac agtatgtata catggaatga
     9301 tgaagctgct gatttctgga aagagcagaa agtcctcaga aatacggtac cgcttgagct
     9361 gaacgaaggg gaaatccgcc acagagataa ccgggacagc gagatgctga tctacggata
     9421 tctgcctctt atgatatcgg cccagtgtgt gcataaaaat ctttacggat gtaatcataa
     9481 ggaagaaggg gtaactttaa aagaccgtta cgataaagaa tttacggcga aatgtatatg
     9541 taacccatgg aaaactgaga atacagattt ctgtataccc tgctataata tcatttacaa
     9601 cagtatccct tacggcctgt tgaaagagaa atcacagata gacagacttg gtgtctcttc
     9661 cctgagactt gcatttacca ttgagaagcc tcaggatgcg gtgaagatat atgaagagtt
     9721 cagagctgtt tatcgtgatg ggaagaatcc tccgaaacgg gaatatacaa agggacattt
     9781 taaaagagga gccgagtaag gcatatgatt aatgtaattg tagaattatc caagtatgtg
     9841 atccttaccc tgatggtgat ttataccttt cactgtttct atctggtgaa acagcagagt
     9901 gaggaggaga gaaacgaatc gctgcgccag cagctgatgc ttatcttttt tatggatttc
     9961 actgcgtttc tggtcatcta cctgaagaca ggtaagtttc aggtcgtgtt gttttatatc
    10021 gaaatgatgg cattttttgc gggaatccag attttgtaca ggatttttta taagaaagca
    10081 tcgattttac tgctcaacaa tatgtgcatg cttctcagcg taggatttat tatgctgtgc
    10141 agactggatg tttccacagc taccagacag ctggtgatcg tggcaggcgt aaatgtggtg
    10201 gcattgatcg tacctgtcct gatcaggaag atgaaatttc tcaaggacct gacatgggtt
    10261 tatgcgggaa tcggaatcgt tttgctggcg gcggtatttg tgcttgcaaa gacaagctat
    10321 ggagcaaaac tttccttgat gggaatccag ccttcagagg cgataaagat tacatttgtg
    10381 ttctttatgg cggcattgct gagaaaaggt gctgattttt caaaagtgat ccaggctacg
    10441 gtagtggcgg gactgcatgt ggggattctt gtactttcca gagaccttgg aagtgcagtg
    10501 atcttctttg cggcatatct tgtgatgatt tatgtggcat ccagaaatgt gggatatctg
    10561 gcacttggtc ttgcaggcgg atctgcaggg gcagttgtcg catatcatct gtttggccat
    10621 gtgcgtcaga gagtgacagc ctggaaggat cccatggcgg tatatcagaa tgaaggatac
    10681 cagatcgtcc agtcactgtt tgccattgga accggcggat ggtttggaat gggattgtgt
    10741 cagggttcgc ctgagaagat ccctgttgtc aagaatgact ttatattcag tgcaatctgt
    10801 gaggaactgg gtgggatttt tgcaatctgc ctgatcctgg tatgtatgag tttctttttg
    10861 atgatcgtaa atattgcgct taagattaag aaaccattct acaaactgat cgcacttgga
    10921 cttggtacgg aatatgcatt tcaggtattt ctgacaattg gcggagcaac gaaatttatc
    10981 cctatgacag gtgtaactct tcctctggtc agctatggag gaagttctgt cgcgtgtaca
    11041 gtactgatgc tggcgatcat tcagggattg tatattttga gagaagatga ggacgaagaa
    11101 attgagagat atcgaagaaa aggaacggcg cagagagttg aagaagcgcc agaagcgcaa
    11161 agcacgggag atttctgaaa agagaaggcc ccgtaacaga gagtatacac tggtatcctg
    11221 cttttttgtg ctgatctttg tcagtatgat cggatatctg atctacttta attatgcaaa
    11281 gagcgatgat tttatcaata gtccctataa tacaaggcag gatacttttt cagacagggt
    11341 tgtaagaggt aagatcatat ctgcagatgg gcaggtgctt gcccagacca atgtttacga
    11401 agacggaaca gaggaacgta cttatcccta tgcaaatatg ttcgctcatg tagtcggata
    11461 tgacactaat ggaaaaagcg gactggaatc agaggcgaac ttccagcttc tgacttctca
    11521 tgaatttttc ctgaaccaga tgaaaaatga gtttaagaat cagaaaaata cgggtgattc
    11581 tgtgatcacg acgttaaacg cagatcttca gtcaactgcc tataatgcac ttggtgacag
    11641 gagaggggcg gttgttgcca tagaaccctc tacaggtaag attctggtgg aaatgagcag
    11701 accggacttt gacccgaata ctatttccca gaactgggac acactggtga atgattccaa
    11761 tgacagcagt ctgttgaaca gagctacaaa cggagcctat cctccgggat ctacatttaa
    11821 ggtggtaact gccctggact atttcagaac caagggcagt ctggagggat tttcctatct
    11881 ctgtgaggga agtattacca gagaagatca cacgatcagg tgctatggcg gaactgttca
    11941 tggacaggaa gatttttaca gtgcttttgc caattcctgt aacagtgcat ttgcagagat
    12001 cggaaccatg ctcggaggca gttctctgaa aaaaacagcc gaggatcttc tttttaataa
    12061 gagtcttccg ctttcttcct ataaaaagag tacttttaca ttaaatggaa aatcttctgt
    12121 tgcagaggtt atgcagactg ccatcggaca gggtaatacg ttggtatcac ctatgcatat
    12181 ggcgctgatt accagtgcaa tcgccaatgg cggggagctc atgaagcctt atctcattga
    12241 ttctgttgta agttcagacg gagagacagt gaagacaaca gagccggaga gctataaacg
    12301 tctgatgaca acaaatgagt cgaatatcct tggaaagctt atgaaaggtg ttgtggaaaa
    12361 cggaaccgca tcggctctga acggaagagg atatacagtg gcaggcaaga ccggatcagc
    12421 ggaatttgat gagaatggtt ccagtcattc ctggtttatc ggttattcca acgtggatga
    12481 tccggatctg gtagttgcga tcattgttga gaatggcggt accggaagtg aagcagcagt
    12541 gcccatcgca gagcagatat ttgatgcgta ttattatgat aagcaataat aaattccatg
    12601 ttgcaggcaa tcgggaatga attttgacta cgttactgtg aacggagtga acagtaacta
    12661 attaatcggt aatatgttat gaaatgatat ttatagcttg cgggtttgga aaaaaagaga
    12721 tatactatac tcagtttata ataccacgca aaacaggagg gattgcatta tgatagaagc
    12781 aacgagctgt ggcggtgtgg taattcatcg gggtaagatt cttactttgt ataaatctta
    12841 caggaaccgt tatgagggct gggtattgcc gaaaggaaca gtggaaccag gcgaaacgca
    12901 tgaacagaca gcattgcggg aagtgatgga agaggctgga gtgcgtgcga ccattgtgaa
    12961 atacatcgga aagagccaat ataactttac cgttccggag gacgtggttt ccaaagaggt
    13021 acactggtat cttatgactg cggataatta tcatagtaag ccccagagag aggagttttt
    13081 tgtagattcc ggatattata aatttcatga gatctatcat ctgctgaggt tttcaaacga
    13141 gaagcagatc gtagagcgtg cttatcagga atatctggag atgagaagca atggactctg
    13201 gggaaaacag cataagtatt attaacgaga gaacagggct gtgttttttt gcaacgcagc
    13261 ccggtttaaa ttttggagaa aatggaaata ctgtaactga agtgttatag aaacgggaga
    13321 gggtgtaaga tgctgaaatg gcaggagaat tttcttgcag gggaatctgt aaaggatcct
    13381 gagaagataa aaaagaaact gaacagcgga aaaccggttc tgggcattta tctccttact
    13441 ctgtcagaga atcctgtgaa tctgatggat attattcctg cagcaatgct gatacagaag
    13501 agcttttatg gaatctgtcc gaagatcata ggaatggcga agggcaaaga ggaagccctg
    13561 gagatggtgc gaagtctgat cgatgaaatg tacagggaaa cgggaacctt cgcaacagct
    13621 gaatatatag aaaacaggtg agaatatgtt acatatttta tggctgatcc ttaaatttat
    13681 actgatcatc ctgggaattc tgctgggcct tcttttactg gcagttcttc ttgtactgtt
    13741 ctgtcctgta agatataagg catcagctgt caaggcagaa ggtggctgga aacagacaga
    13801 gggagagggt atcgtaagct ggctgtttca tgggatttcg ctgagagcgg aatggaaaga
    13861 tcagcagatg gagatatcct ttcatctgtt tggaattccc gtagacaagt tgttgaaaaa
    13921 acggaaggag aagagggata taacaaagaa atccgggaaa aatccggaga aatccggcgc
    13981 agaaaaggta tctgtatccg gcatagacgg aaacagggaa gaagagcata aaaaatcagt
    14041 ggttgatcac ccgaaatcag agaatatgga gactgaggat ctgaaaacag acagaaattc
    14101 agcttcagat acatctgctg atacagagag gatcagaaac agtcagatat ccggacagca
    14161 ggaactgaat gcagatgata cagatcggaa tagtctaaag aagaggcagt tttttataaa
    14221 aaggatctat gaccggatcc gaaatatatt tcagtcgatt cgtacaaaac tgcaaaatat
    14281 ccgcaggaca ttcgggaaga ttaagaagaa tgtgtcctgg tggaaggcgt ttatagaaca
    14341 tcccagagtg acagctgcca gaaagcttgt atggaaacat ggaaaatttt tgcttaagca
    14401 tatttttcct acaaggatag aagggcaggt tactttttct tttgaagatc cggcgctgac
    14461 aggtgcggca cttgctgtac ttgggatgac aattccattt cacaaaaact gtatacagat
    14521 caatccccgt tttgacagtg agaattatct atatggaaac atcagggcaa aaggcaggat
    14581 ctacggattt gttcctgtgc gggcagcagt gagtatttat ttcaataaaa atataaaata
    14641 cgttataaaa cgttggaaaa ccaggagggc atgaccatgg caaatgaaaa caattttaaa
    14701 gaaaccgtaa attcattatt caagggaatg gacagtttta tttctgcgaa aacagtggta
    14761 ggagaggcaa tccatgtagg cgatacgatc attcttcctc tgatggatgt atctttcggt
    14821 gtaggtgccg gtgctttttc aggagagaag aaggataacg gcggcggcgg aatggcagga
    14881 aagatgactc cctgtgcagt gcttgtgatc cagaatggaa caacaaagct ggtcaatgtg
    14941 aaaaatcagg atggtctcac caagatcctt gatatggttc cggattttgt agatcgtttt
    15001 acctccggaa aaggtgacga agaatctgtc ggcgaatcag aaaaataatt tttgcataga
    15061 ctatagcaaa ccgatgaaaa aggtgcagaa ga
//
